Incidental Mutation 'R1905:Tanc2'
| ID |
214311 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Tanc2
|
| Ensembl Gene |
ENSMUSG00000053580 |
| Gene Name |
tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 |
| Synonyms |
5730590C14Rik, 3526402J09Rik |
| MMRRC Submission |
039924-MU
|
| Accession Numbers |
|
| Essential gene? |
Essential
(E-score: 1.000)
|
| Stock # |
R1905 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
|
| Chromosome |
11 |
| Chromosomal Location |
105480812-105820130 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
G to A
at 105813689 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Glycine to Aspartic acid
at position 1711
(G1711D)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000097904
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000100330]
|
| AlphaFold |
A2A690 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000089485
|
| SMART Domains |
Protein: ENSMUSP00000086912
Gene: ENSMUSG00000053580
| Domain | Start | End | E-Value | Type |
|---|
|
ANK
|
35 |
63 |
1.16e3 |
SMART |
|
ANK
|
78 |
107 |
3.31e-1 |
SMART |
|
ANK
|
111 |
140 |
7.71e-2 |
SMART |
|
ANK
|
144 |
173 |
6.12e-5 |
SMART |
|
ANK
|
177 |
206 |
8.99e-3 |
SMART |
|
ANK
|
210 |
239 |
5.71e-5 |
SMART |
|
ANK
|
243 |
272 |
2.11e2 |
SMART |
|
Blast:TPR
|
289 |
322 |
3e-14 |
BLAST |
|
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000100330
AA Change: G1711D
PolyPhen 2
Score 0.605 (Sensitivity: 0.87; Specificity: 0.91)
|
| SMART Domains |
Protein: ENSMUSP00000097904
Gene: ENSMUSG00000053580
AA Change: G1711D
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
32 |
50 |
N/A |
INTRINSIC |
|
low complexity region
|
129 |
152 |
N/A |
INTRINSIC |
|
low complexity region
|
362 |
375 |
N/A |
INTRINSIC |
|
low complexity region
|
436 |
447 |
N/A |
INTRINSIC |
|
low complexity region
|
823 |
834 |
N/A |
INTRINSIC |
|
ANK
|
846 |
878 |
2.08e3 |
SMART |
|
ANK
|
882 |
913 |
2.97e2 |
SMART |
|
ANK
|
917 |
946 |
5.75e-1 |
SMART |
|
ANK
|
950 |
979 |
8.62e1 |
SMART |
|
ANK
|
990 |
1018 |
1.16e3 |
SMART |
|
ANK
|
1033 |
1062 |
3.31e-1 |
SMART |
|
ANK
|
1066 |
1095 |
7.71e-2 |
SMART |
|
ANK
|
1099 |
1128 |
6.12e-5 |
SMART |
|
ANK
|
1132 |
1161 |
8.99e-3 |
SMART |
|
ANK
|
1165 |
1194 |
5.71e-5 |
SMART |
|
ANK
|
1198 |
1227 |
2.11e2 |
SMART |
|
TPR
|
1244 |
1277 |
3.89e1 |
SMART |
|
TPR
|
1291 |
1324 |
3.61e-2 |
SMART |
|
TPR
|
1325 |
1358 |
2.82e-4 |
SMART |
|
low complexity region
|
1369 |
1406 |
N/A |
INTRINSIC |
|
low complexity region
|
1533 |
1539 |
N/A |
INTRINSIC |
|
low complexity region
|
1787 |
1802 |
N/A |
INTRINSIC |
|
| Predicted Effect |
unknown
Transcript: ENSMUST00000146162
AA Change: G853D
|
| SMART Domains |
Protein: ENSMUSP00000123674
Gene: ENSMUSG00000053580
AA Change: G853D
| Domain | Start | End | E-Value | Type |
|---|
|
ANK
|
15 |
46 |
2.97e2 |
SMART |
|
ANK
|
50 |
79 |
5.75e-1 |
SMART |
|
ANK
|
83 |
112 |
8.62e1 |
SMART |
|
ANK
|
123 |
151 |
1.16e3 |
SMART |
|
ANK
|
166 |
195 |
3.31e-1 |
SMART |
|
ANK
|
199 |
228 |
7.71e-2 |
SMART |
|
ANK
|
232 |
261 |
6.12e-5 |
SMART |
|
ANK
|
265 |
294 |
8.99e-3 |
SMART |
|
ANK
|
298 |
327 |
5.71e-5 |
SMART |
|
ANK
|
331 |
360 |
3.44e1 |
SMART |
|
TPR
|
387 |
420 |
3.89e1 |
SMART |
|
TPR
|
434 |
467 |
3.61e-2 |
SMART |
|
TPR
|
468 |
501 |
2.82e-4 |
SMART |
|
low complexity region
|
512 |
549 |
N/A |
INTRINSIC |
|
low complexity region
|
676 |
682 |
N/A |
INTRINSIC |
|
low complexity region
|
930 |
945 |
N/A |
INTRINSIC |
|
| Meta Mutation Damage Score |
0.1046 |
| Coding Region Coverage |
- 1x: 97.5%
- 3x: 97.0%
- 10x: 95.5%
- 20x: 93.1%
|
| Validation Efficiency |
99% (90/91) |
| MGI Phenotype |
PHENOTYPE: Mice homozygous for a gene trap vector die prior to E12. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 89 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 4833420G17Rik |
G |
T |
13: 119,606,216 (GRCm39) |
V153L |
possibly damaging |
Het |
| Adamts17 |
T |
A |
7: 66,697,220 (GRCm39) |
C631* |
probably null |
Het |
| Adamts19 |
A |
G |
18: 59,166,017 (GRCm39) |
R1070G |
possibly damaging |
Het |
| Aldh1a1 |
A |
G |
19: 20,595,362 (GRCm39) |
E97G |
probably damaging |
Het |
| Bola2 |
T |
A |
7: 126,295,410 (GRCm39) |
V40E |
probably damaging |
Het |
| Ccar1 |
A |
G |
10: 62,612,437 (GRCm39) |
S243P |
possibly damaging |
Het |
| Cd80 |
A |
T |
16: 38,294,539 (GRCm39) |
I141F |
probably damaging |
Het |
| Ceacam23 |
T |
A |
7: 17,607,477 (GRCm39) |
|
noncoding transcript |
Het |
| Chn2 |
T |
C |
6: 54,263,106 (GRCm39) |
C92R |
probably damaging |
Het |
| Ciao2a |
A |
G |
9: 66,039,929 (GRCm39) |
K82R |
probably benign |
Het |
| Clk1 |
A |
T |
1: 58,461,101 (GRCm39) |
|
probably benign |
Het |
| Clock |
T |
C |
5: 76,414,735 (GRCm39) |
|
probably benign |
Het |
| Cntnap3 |
A |
G |
13: 65,051,578 (GRCm39) |
V26A |
probably benign |
Het |
| Csf3r |
A |
T |
4: 125,936,538 (GRCm39) |
K651N |
probably benign |
Het |
| Cul4a |
T |
C |
8: 13,183,171 (GRCm39) |
M322T |
probably benign |
Het |
| Cx3cl1 |
A |
G |
8: 95,506,687 (GRCm39) |
T231A |
probably benign |
Het |
| Cyp2c68 |
A |
T |
19: 39,724,026 (GRCm39) |
C213S |
probably benign |
Het |
| Dhx16 |
T |
G |
17: 36,199,247 (GRCm39) |
S814A |
probably benign |
Het |
| Dnah1 |
T |
C |
14: 30,986,587 (GRCm39) |
I3659V |
probably benign |
Het |
| Dock6 |
A |
T |
9: 21,740,870 (GRCm39) |
V906D |
probably benign |
Het |
| Ep400 |
G |
A |
5: 110,818,814 (GRCm39) |
T2738I |
probably damaging |
Het |
| Erbb4 |
A |
T |
1: 68,114,569 (GRCm39) |
|
probably benign |
Het |
| Fam135b |
C |
T |
15: 71,404,836 (GRCm39) |
R70H |
probably damaging |
Het |
| Fam13a |
T |
C |
6: 58,930,475 (GRCm39) |
Q479R |
probably damaging |
Het |
| Fcgr4 |
A |
T |
1: 170,856,874 (GRCm39) |
Q247L |
probably damaging |
Het |
| Flnc |
T |
A |
6: 29,459,459 (GRCm39) |
C2520S |
probably damaging |
Het |
| Foxn1 |
A |
G |
11: 78,262,636 (GRCm39) |
|
probably null |
Het |
| Fsip2 |
C |
T |
2: 82,813,772 (GRCm39) |
P3364S |
possibly damaging |
Het |
| Fzd8 |
C |
T |
18: 9,213,803 (GRCm39) |
T295I |
probably damaging |
Het |
| Gm4744 |
G |
A |
6: 40,928,736 (GRCm39) |
|
probably benign |
Het |
| Gm4871 |
G |
T |
5: 144,966,859 (GRCm39) |
A208D |
probably damaging |
Het |
| Gm527 |
A |
G |
12: 64,967,797 (GRCm39) |
N73S |
possibly damaging |
Het |
| Gm5414 |
T |
C |
15: 101,533,075 (GRCm39) |
I451V |
probably damaging |
Het |
| Golm1 |
A |
T |
13: 59,790,065 (GRCm39) |
V245E |
probably benign |
Het |
| Grik1 |
A |
T |
16: 87,693,754 (GRCm39) |
Y879* |
probably null |
Het |
| Grn |
C |
A |
11: 102,327,276 (GRCm39) |
P241Q |
probably damaging |
Het |
| H2-T7 |
T |
C |
17: 36,453,833 (GRCm39) |
|
noncoding transcript |
Het |
| Hjurp |
T |
C |
1: 88,194,338 (GRCm39) |
E190G |
probably benign |
Het |
| Hmcn1 |
A |
C |
1: 150,868,606 (GRCm39) |
I66S |
probably damaging |
Het |
| Hykk |
T |
A |
9: 54,853,667 (GRCm39) |
Y330N |
probably benign |
Het |
| Khdc1c |
A |
G |
1: 21,439,281 (GRCm39) |
N89S |
probably benign |
Het |
| Lcor |
A |
G |
19: 41,572,013 (GRCm39) |
D256G |
possibly damaging |
Het |
| Lrrc72 |
T |
A |
12: 36,258,661 (GRCm39) |
|
probably null |
Het |
| Lyst |
T |
G |
13: 13,808,719 (GRCm39) |
S130A |
probably benign |
Het |
| Mast1 |
G |
A |
8: 85,642,895 (GRCm39) |
R967C |
probably damaging |
Het |
| Mfng |
T |
C |
15: 78,657,286 (GRCm39) |
T63A |
probably damaging |
Het |
| Mre11a |
G |
A |
9: 14,710,923 (GRCm39) |
D206N |
probably benign |
Het |
| Myh10 |
A |
G |
11: 68,662,694 (GRCm39) |
|
probably benign |
Het |
| Myt1 |
A |
G |
2: 181,439,549 (GRCm39) |
D357G |
probably damaging |
Het |
| Nacad |
T |
A |
11: 6,552,540 (GRCm39) |
H217L |
probably benign |
Het |
| Ncoa1 |
A |
G |
12: 4,345,433 (GRCm39) |
V638A |
probably damaging |
Het |
| Nlrp3 |
T |
G |
11: 59,439,862 (GRCm39) |
F480V |
probably damaging |
Het |
| Nos1ap |
A |
G |
1: 170,146,127 (GRCm39) |
W476R |
possibly damaging |
Het |
| Nr1h4 |
T |
A |
10: 89,316,421 (GRCm39) |
T220S |
possibly damaging |
Het |
| Ntf5 |
G |
T |
7: 45,065,176 (GRCm39) |
V103L |
probably damaging |
Het |
| Ntm |
C |
A |
9: 29,090,393 (GRCm39) |
D109Y |
probably damaging |
Het |
| Or7e178 |
C |
T |
9: 20,226,142 (GRCm39) |
E17K |
probably benign |
Het |
| P2rx7 |
G |
A |
5: 122,819,015 (GRCm39) |
C479Y |
probably damaging |
Het |
| Pappa2 |
T |
A |
1: 158,631,073 (GRCm39) |
|
probably null |
Het |
| Pgap1 |
A |
C |
1: 54,551,120 (GRCm39) |
I520R |
probably benign |
Het |
| Pikfyve |
G |
A |
1: 65,231,454 (GRCm39) |
|
probably null |
Het |
| Plekhg3 |
T |
C |
12: 76,622,991 (GRCm39) |
S744P |
probably benign |
Het |
| Pramel6 |
A |
G |
2: 87,339,526 (GRCm39) |
R97G |
probably damaging |
Het |
| Pramel6 |
G |
T |
2: 87,339,527 (GRCm39) |
R97M |
probably damaging |
Het |
| Psme4 |
T |
C |
11: 30,760,922 (GRCm39) |
V397A |
probably damaging |
Het |
| Ptk2b |
T |
C |
14: 66,396,119 (GRCm39) |
D783G |
probably damaging |
Het |
| Ptma-ps1 |
T |
A |
7: 23,763,306 (GRCm39) |
L17* |
probably null |
Het |
| Ralgapa2 |
C |
A |
2: 146,229,621 (GRCm39) |
R1053L |
probably damaging |
Het |
| Sap130 |
C |
T |
18: 31,813,620 (GRCm39) |
P559L |
possibly damaging |
Het |
| Sap30 |
T |
C |
8: 57,940,345 (GRCm39) |
S86G |
probably damaging |
Het |
| Sdk2 |
C |
T |
11: 113,729,472 (GRCm39) |
|
silent |
Het |
| Sema3f |
G |
T |
9: 107,561,575 (GRCm39) |
Q500K |
probably damaging |
Het |
| Serpinb3d |
T |
C |
1: 107,007,014 (GRCm39) |
I231M |
possibly damaging |
Het |
| Sf3a1 |
T |
A |
11: 4,126,678 (GRCm39) |
N563K |
probably benign |
Het |
| Sipa1l3 |
A |
G |
7: 29,038,592 (GRCm39) |
S352P |
possibly damaging |
Het |
| Slc6a12 |
G |
T |
6: 121,324,402 (GRCm39) |
E9* |
probably null |
Het |
| Srebf1 |
T |
C |
11: 60,095,319 (GRCm39) |
D400G |
probably damaging |
Het |
| Swsap1 |
T |
C |
9: 21,867,988 (GRCm39) |
Y87H |
probably damaging |
Het |
| Tas2r107 |
T |
C |
6: 131,636,951 (GRCm39) |
M33V |
probably benign |
Het |
| Tdrd9 |
T |
A |
12: 112,030,061 (GRCm39) |
|
probably benign |
Het |
| Tdrp |
T |
C |
8: 14,004,079 (GRCm39) |
D86G |
probably damaging |
Het |
| Tmem92 |
A |
T |
11: 94,669,501 (GRCm39) |
M106K |
probably benign |
Het |
| Tmf1 |
A |
T |
6: 97,138,440 (GRCm39) |
C764S |
possibly damaging |
Het |
| Ttc21a |
G |
T |
9: 119,795,823 (GRCm39) |
R1219L |
possibly damaging |
Het |
| Ttn |
C |
T |
2: 76,593,792 (GRCm39) |
G18870D |
probably damaging |
Het |
| Tubgcp6 |
T |
C |
15: 88,984,811 (GRCm39) |
Y1732C |
probably damaging |
Het |
| Vmn1r28 |
A |
G |
6: 58,242,912 (GRCm39) |
T252A |
probably benign |
Het |
| Xirp2 |
A |
G |
2: 67,346,700 (GRCm39) |
I2980M |
probably damaging |
Het |
| Zc2hc1c |
A |
G |
12: 85,337,288 (GRCm39) |
D315G |
probably benign |
Het |
|
| Other mutations in Tanc2 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00501:Tanc2
|
APN |
11 |
105,814,046 (GRCm39) |
missense |
probably benign |
0.28 |
|
IGL00688:Tanc2
|
APN |
11 |
105,689,516 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL00709:Tanc2
|
APN |
11 |
105,689,621 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01013:Tanc2
|
APN |
11 |
105,515,891 (GRCm39) |
missense |
probably damaging |
0.96 |
|
IGL01141:Tanc2
|
APN |
11 |
105,777,300 (GRCm39) |
splice site |
probably benign |
|
|
IGL01386:Tanc2
|
APN |
11 |
105,777,207 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL01433:Tanc2
|
APN |
11 |
105,701,348 (GRCm39) |
missense |
possibly damaging |
0.75 |
|
IGL01562:Tanc2
|
APN |
11 |
105,670,895 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL01979:Tanc2
|
APN |
11 |
105,667,746 (GRCm39) |
missense |
probably benign |
|
|
IGL02104:Tanc2
|
APN |
11 |
105,670,959 (GRCm39) |
unclassified |
probably benign |
|
|
IGL02434:Tanc2
|
APN |
11 |
105,670,868 (GRCm39) |
missense |
probably benign |
0.14 |
|
IGL02534:Tanc2
|
APN |
11 |
105,725,994 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02568:Tanc2
|
APN |
11 |
105,667,777 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL03279:Tanc2
|
APN |
11 |
105,803,918 (GRCm39) |
splice site |
probably null |
|
|
R0595:Tanc2
|
UTSW |
11 |
105,605,003 (GRCm39) |
splice site |
probably null |
|
|
R1131:Tanc2
|
UTSW |
11 |
105,725,828 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1320:Tanc2
|
UTSW |
11 |
105,777,270 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1487:Tanc2
|
UTSW |
11 |
105,814,460 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1497:Tanc2
|
UTSW |
11 |
105,812,963 (GRCm39) |
missense |
probably benign |
0.21 |
|
R1692:Tanc2
|
UTSW |
11 |
105,748,326 (GRCm39) |
missense |
probably benign |
|
|
R1712:Tanc2
|
UTSW |
11 |
105,790,606 (GRCm39) |
missense |
probably benign |
|
|
R1793:Tanc2
|
UTSW |
11 |
105,515,859 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R1812:Tanc2
|
UTSW |
11 |
105,777,212 (GRCm39) |
missense |
probably benign |
0.01 |
|
R1959:Tanc2
|
UTSW |
11 |
105,801,121 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1962:Tanc2
|
UTSW |
11 |
105,689,558 (GRCm39) |
missense |
probably benign |
0.14 |
|
R2122:Tanc2
|
UTSW |
11 |
105,786,775 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2174:Tanc2
|
UTSW |
11 |
105,801,135 (GRCm39) |
missense |
probably benign |
0.00 |
|
R2341:Tanc2
|
UTSW |
11 |
105,725,877 (GRCm39) |
missense |
probably benign |
0.09 |
|
R2497:Tanc2
|
UTSW |
11 |
105,564,319 (GRCm39) |
critical splice donor site |
probably null |
|
|
R3438:Tanc2
|
UTSW |
11 |
105,748,401 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R3711:Tanc2
|
UTSW |
11 |
105,689,516 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3765:Tanc2
|
UTSW |
11 |
105,805,796 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3890:Tanc2
|
UTSW |
11 |
105,689,504 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4193:Tanc2
|
UTSW |
11 |
105,804,888 (GRCm39) |
intron |
probably benign |
|
|
R4609:Tanc2
|
UTSW |
11 |
105,801,066 (GRCm39) |
missense |
probably benign |
0.24 |
|
R4674:Tanc2
|
UTSW |
11 |
105,758,306 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4928:Tanc2
|
UTSW |
11 |
105,758,588 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5008:Tanc2
|
UTSW |
11 |
105,515,886 (GRCm39) |
start codon destroyed |
probably null |
0.46 |
|
R5010:Tanc2
|
UTSW |
11 |
105,670,918 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5135:Tanc2
|
UTSW |
11 |
105,748,379 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R5385:Tanc2
|
UTSW |
11 |
105,667,672 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5409:Tanc2
|
UTSW |
11 |
105,758,311 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R5419:Tanc2
|
UTSW |
11 |
105,813,709 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5501:Tanc2
|
UTSW |
11 |
105,805,811 (GRCm39) |
critical splice donor site |
probably null |
|
|
R5590:Tanc2
|
UTSW |
11 |
105,814,132 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5651:Tanc2
|
UTSW |
11 |
105,689,526 (GRCm39) |
missense |
probably benign |
0.44 |
|
R5798:Tanc2
|
UTSW |
11 |
105,812,681 (GRCm39) |
small deletion |
probably benign |
|
|
R5876:Tanc2
|
UTSW |
11 |
105,813,439 (GRCm39) |
missense |
possibly damaging |
0.71 |
|
R5889:Tanc2
|
UTSW |
11 |
105,812,633 (GRCm39) |
missense |
probably benign |
0.23 |
|
R5958:Tanc2
|
UTSW |
11 |
105,731,451 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5999:Tanc2
|
UTSW |
11 |
105,758,543 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6024:Tanc2
|
UTSW |
11 |
105,814,498 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6024:Tanc2
|
UTSW |
11 |
105,758,543 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6025:Tanc2
|
UTSW |
11 |
105,787,373 (GRCm39) |
missense |
possibly damaging |
0.68 |
|
R6025:Tanc2
|
UTSW |
11 |
105,758,543 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6048:Tanc2
|
UTSW |
11 |
105,758,543 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6049:Tanc2
|
UTSW |
11 |
105,758,543 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6185:Tanc2
|
UTSW |
11 |
105,803,865 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6335:Tanc2
|
UTSW |
11 |
105,748,382 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6821:Tanc2
|
UTSW |
11 |
105,777,316 (GRCm39) |
splice site |
probably null |
|
|
R6846:Tanc2
|
UTSW |
11 |
105,689,479 (GRCm39) |
missense |
probably benign |
0.34 |
|
R6857:Tanc2
|
UTSW |
11 |
105,801,114 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
R6904:Tanc2
|
UTSW |
11 |
105,726,056 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R7009:Tanc2
|
UTSW |
11 |
105,731,525 (GRCm39) |
missense |
possibly damaging |
0.47 |
|
R7017:Tanc2
|
UTSW |
11 |
105,813,934 (GRCm39) |
missense |
probably benign |
|
|
R7371:Tanc2
|
UTSW |
11 |
105,689,422 (GRCm39) |
missense |
probably benign |
|
|
R7556:Tanc2
|
UTSW |
11 |
105,799,857 (GRCm39) |
missense |
|
|
|
R7630:Tanc2
|
UTSW |
11 |
105,667,734 (GRCm39) |
missense |
probably benign |
0.04 |
|
R7693:Tanc2
|
UTSW |
11 |
105,814,293 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7757:Tanc2
|
UTSW |
11 |
105,667,684 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
R7807:Tanc2
|
UTSW |
11 |
105,758,480 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7878:Tanc2
|
UTSW |
11 |
105,804,241 (GRCm39) |
missense |
|
|
|
R7895:Tanc2
|
UTSW |
11 |
105,812,651 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7952:Tanc2
|
UTSW |
11 |
105,787,423 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8099:Tanc2
|
UTSW |
11 |
105,754,833 (GRCm39) |
missense |
probably benign |
0.17 |
|
R8117:Tanc2
|
UTSW |
11 |
105,725,988 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8133:Tanc2
|
UTSW |
11 |
105,814,048 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R8422:Tanc2
|
UTSW |
11 |
105,726,014 (GRCm39) |
missense |
probably benign |
0.10 |
|
R8527:Tanc2
|
UTSW |
11 |
105,807,834 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R8542:Tanc2
|
UTSW |
11 |
105,807,834 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R8834:Tanc2
|
UTSW |
11 |
105,807,845 (GRCm39) |
missense |
|
|
|
R8912:Tanc2
|
UTSW |
11 |
105,758,153 (GRCm39) |
missense |
probably benign |
0.01 |
|
R8927:Tanc2
|
UTSW |
11 |
105,701,331 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8928:Tanc2
|
UTSW |
11 |
105,701,331 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8968:Tanc2
|
UTSW |
11 |
105,758,400 (GRCm39) |
missense |
possibly damaging |
0.50 |
|
R9065:Tanc2
|
UTSW |
11 |
105,689,518 (GRCm39) |
nonsense |
probably null |
|
|
R9095:Tanc2
|
UTSW |
11 |
105,758,104 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9108:Tanc2
|
UTSW |
11 |
105,810,580 (GRCm39) |
intron |
probably benign |
|
|
R9131:Tanc2
|
UTSW |
11 |
105,689,603 (GRCm39) |
missense |
probably benign |
|
|
R9294:Tanc2
|
UTSW |
11 |
105,777,284 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9445:Tanc2
|
UTSW |
11 |
105,758,290 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
X0027:Tanc2
|
UTSW |
11 |
105,726,009 (GRCm39) |
missense |
probably benign |
0.26 |
|
| Predicted Primers |
PCR Primer
(F):5'- CATGGGAGTAAGTCAGAGCC -3'
(R):5'- CTATTGCTGGATGGAGAAAAGC -3'
Sequencing Primer
(F):5'- AAGTCAGAGCCGATTGGTTTATCAG -3'
(R):5'- ACTCTGTGAGTGCAGCAGC -3'
|
| Posted On |
2014-07-14 |
Incidental Mutation