Incidental Mutation 'R1907:Dscaml1'
| ID |
214481 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Dscaml1
|
| Ensembl Gene |
ENSMUSG00000032087 |
| Gene Name |
DS cell adhesion molecule like 1 |
| Synonyms |
4921507G06Rik, 4930435C18Rik |
| MMRRC Submission |
039926-MU
|
| Accession Numbers |
|
| Essential gene? |
Possibly non essential
(E-score: 0.416)
|
| Stock # |
R1907 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
|
| Chromosome |
9 |
| Chromosomal Location |
45338735-45665011 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
G to A
at 45651778 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Glycine to Aspartic acid
at position 277
(G277D)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000034592]
|
| AlphaFold |
Q4VA61 |
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000034592
AA Change: A1295T
PolyPhen 2
Score 0.895 (Sensitivity: 0.82; Specificity: 0.94)
|
| SMART Domains |
Protein: ENSMUSP00000034592
Gene: ENSMUSG00000032087
AA Change: A1295T
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
3 |
17 |
N/A |
INTRINSIC |
|
low complexity region
|
28 |
55 |
N/A |
INTRINSIC |
|
IG_like
|
96 |
168 |
1.22e0 |
SMART |
|
IG
|
189 |
277 |
1.15e-3 |
SMART |
|
IGc2
|
296 |
359 |
2.54e-14 |
SMART |
|
IGc2
|
385 |
451 |
8.12e-13 |
SMART |
|
IGc2
|
478 |
550 |
9.55e-10 |
SMART |
|
IGc2
|
575 |
640 |
9.78e-7 |
SMART |
|
IGc2
|
666 |
734 |
5.93e-6 |
SMART |
|
IGc2
|
760 |
832 |
6.75e-10 |
SMART |
|
IG
|
853 |
943 |
1e-3 |
SMART |
|
FN3
|
945 |
1029 |
6.64e-7 |
SMART |
|
FN3
|
1045 |
1133 |
9.46e-12 |
SMART |
|
FN3
|
1148 |
1234 |
3.2e-9 |
SMART |
|
FN3
|
1249 |
1332 |
3.48e-10 |
SMART |
|
IGc2
|
1363 |
1428 |
1.49e-11 |
SMART |
|
FN3
|
1442 |
1522 |
3.42e-9 |
SMART |
|
FN3
|
1537 |
1618 |
2.14e-1 |
SMART |
|
low complexity region
|
1671 |
1683 |
N/A |
INTRINSIC |
|
low complexity region
|
2018 |
2026 |
N/A |
INTRINSIC |
|
low complexity region
|
2035 |
2069 |
N/A |
INTRINSIC |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000215027
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000216685
AA Change: G277D
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| Meta Mutation Damage Score |
0.6467 |
| Coding Region Coverage |
- 1x: 97.5%
- 3x: 97.0%
- 10x: 95.6%
- 20x: 93.4%
|
| Validation Efficiency |
98% (104/106) |
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] The protein encoded by this gene is a member of the Ig superfamily of cell adhesion molecules and is involved in neuronal differentiation. The encoded membrane-bound protein localizes to the cell surface, where it forms aggregates that repel neuronal processes of the same cell type. [provided by RefSeq, Sep 2016]
PHENOTYPE: Mice homozygous for a gene trapped allele exhibit impaired self-avoidance in multiple cell types in the retina. [provided by MGI curators]
|
| Allele List at MGI |
All alleles(4) : Gene trapped(4) |
| Other mutations in this stock |
Total: 104 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Abca4 |
C |
A |
3: 121,862,661 (GRCm39) |
S206R |
probably damaging |
Het |
| Abcc6 |
G |
T |
7: 45,663,593 (GRCm39) |
A357E |
probably benign |
Het |
| Abhd13 |
T |
A |
8: 10,038,170 (GRCm39) |
C256S |
probably benign |
Het |
| Actrt3 |
A |
G |
3: 30,652,716 (GRCm39) |
V126A |
probably damaging |
Het |
| Adgrv1 |
A |
G |
13: 81,740,670 (GRCm39) |
|
probably benign |
Het |
| Alyref2 |
A |
G |
1: 171,331,838 (GRCm39) |
D205G |
probably damaging |
Het |
| Amigo3 |
G |
A |
9: 107,930,835 (GRCm39) |
R86Q |
probably benign |
Het |
| Ankrd50 |
G |
C |
3: 38,508,201 (GRCm39) |
P1389A |
probably damaging |
Het |
| Aoah |
A |
G |
13: 21,094,264 (GRCm39) |
D183G |
probably damaging |
Het |
| Arap3 |
A |
T |
18: 38,129,724 (GRCm39) |
S146T |
probably benign |
Het |
| Atp2c2 |
T |
C |
8: 120,476,615 (GRCm39) |
|
probably benign |
Het |
| Atp8b2 |
C |
T |
3: 89,853,583 (GRCm39) |
V682M |
probably benign |
Het |
| Cacna1i |
T |
C |
15: 80,259,465 (GRCm39) |
I1245T |
probably damaging |
Het |
| Card14 |
A |
G |
11: 119,222,085 (GRCm39) |
N460S |
probably benign |
Het |
| Ceacam5 |
A |
G |
7: 17,486,309 (GRCm39) |
D602G |
possibly damaging |
Het |
| Cecr2 |
T |
A |
6: 120,738,121 (GRCm39) |
H921Q |
probably benign |
Het |
| Cyb5d1 |
T |
C |
11: 69,285,566 (GRCm39) |
D115G |
probably benign |
Het |
| Dbp |
C |
T |
7: 45,357,744 (GRCm39) |
T67I |
possibly damaging |
Het |
| Dennd5b |
C |
T |
6: 148,943,074 (GRCm39) |
V601I |
probably benign |
Het |
| Dnah11 |
G |
A |
12: 118,091,291 (GRCm39) |
A947V |
possibly damaging |
Het |
| Dpysl3 |
T |
A |
18: 43,571,193 (GRCm39) |
D27V |
probably damaging |
Het |
| Drd1 |
A |
T |
13: 54,207,271 (GRCm39) |
D307E |
possibly damaging |
Het |
| Eif4g3 |
C |
T |
4: 137,885,726 (GRCm39) |
R842W |
probably damaging |
Het |
| Enam |
C |
T |
5: 88,652,481 (GRCm39) |
T1330I |
possibly damaging |
Het |
| Fabp6 |
T |
C |
11: 43,486,994 (GRCm39) |
|
probably null |
Het |
| Fcsk |
A |
T |
8: 111,620,010 (GRCm39) |
L289* |
probably null |
Het |
| Fhip1a |
T |
C |
3: 85,579,940 (GRCm39) |
D755G |
probably benign |
Het |
| Fsip2 |
C |
T |
2: 82,813,772 (GRCm39) |
P3364S |
possibly damaging |
Het |
| Gad1 |
C |
T |
2: 70,409,482 (GRCm39) |
S191F |
possibly damaging |
Het |
| Gcm1 |
A |
C |
9: 77,972,055 (GRCm39) |
N332T |
probably benign |
Het |
| Gin1 |
G |
A |
1: 97,703,172 (GRCm39) |
|
probably benign |
Het |
| Gpr25 |
T |
C |
1: 136,188,538 (GRCm39) |
D25G |
probably benign |
Het |
| Gstm4 |
T |
C |
3: 107,948,593 (GRCm39) |
T172A |
probably benign |
Het |
| Hnrnpll |
A |
G |
17: 80,342,758 (GRCm39) |
|
probably null |
Het |
| Il12rb2 |
T |
A |
6: 67,272,270 (GRCm39) |
K339* |
probably null |
Het |
| Inpp1 |
A |
G |
1: 52,828,829 (GRCm39) |
*397Q |
probably null |
Het |
| Kcp |
G |
T |
6: 29,497,834 (GRCm39) |
|
probably benign |
Het |
| Kdm1b |
G |
A |
13: 47,217,596 (GRCm39) |
V352I |
probably benign |
Het |
| Klhdc2 |
G |
T |
12: 69,343,734 (GRCm39) |
|
probably benign |
Het |
| Krt75 |
T |
A |
15: 101,481,801 (GRCm39) |
T156S |
possibly damaging |
Het |
| Lag3 |
T |
A |
6: 124,886,450 (GRCm39) |
I168F |
possibly damaging |
Het |
| Lama4 |
T |
G |
10: 38,948,754 (GRCm39) |
V839G |
probably benign |
Het |
| Lmtk2 |
G |
T |
5: 144,111,928 (GRCm39) |
V883L |
probably benign |
Het |
| Lrrc37a |
C |
A |
11: 103,347,982 (GRCm39) |
K2904N |
unknown |
Het |
| Macf1 |
A |
T |
4: 123,266,192 (GRCm39) |
I4775N |
probably damaging |
Het |
| Map2k3 |
T |
G |
11: 60,823,055 (GRCm39) |
S3A |
possibly damaging |
Het |
| Mast1 |
G |
A |
8: 85,642,895 (GRCm39) |
R967C |
probably damaging |
Het |
| Mettl2 |
T |
G |
11: 105,017,666 (GRCm39) |
S59A |
probably benign |
Het |
| Mtr |
G |
A |
13: 12,240,418 (GRCm39) |
T530I |
probably damaging |
Het |
| Myo7b |
A |
T |
18: 32,110,052 (GRCm39) |
C1137S |
possibly damaging |
Het |
| Nacad |
T |
A |
11: 6,552,540 (GRCm39) |
H217L |
probably benign |
Het |
| Ncstn |
A |
T |
1: 171,899,710 (GRCm39) |
V324E |
probably damaging |
Het |
| Ndufaf7 |
C |
A |
17: 79,249,546 (GRCm39) |
H148N |
possibly damaging |
Het |
| Or10a49 |
T |
A |
7: 108,467,705 (GRCm39) |
I219F |
possibly damaging |
Het |
| Or52a24 |
T |
A |
7: 103,381,190 (GRCm39) |
I19N |
probably damaging |
Het |
| Or52n2b |
G |
A |
7: 104,566,272 (GRCm39) |
T77I |
probably damaging |
Het |
| Or7g12 |
T |
C |
9: 18,899,737 (GRCm39) |
I151T |
possibly damaging |
Het |
| Or8b12 |
T |
G |
9: 37,657,729 (GRCm39) |
L100V |
probably benign |
Het |
| Or8k17 |
T |
C |
2: 86,066,454 (GRCm39) |
K242E |
possibly damaging |
Het |
| Pcdh20 |
T |
C |
14: 88,706,140 (GRCm39) |
I387V |
probably benign |
Het |
| Pclo |
A |
G |
5: 14,728,525 (GRCm39) |
|
probably benign |
Het |
| Pcp2 |
G |
A |
8: 3,674,904 (GRCm39) |
|
probably benign |
Het |
| Pde1a |
T |
A |
2: 79,698,651 (GRCm39) |
D393V |
probably damaging |
Het |
| Pias4 |
T |
C |
10: 80,990,197 (GRCm39) |
D421G |
possibly damaging |
Het |
| Pign |
T |
C |
1: 105,565,940 (GRCm39) |
T362A |
possibly damaging |
Het |
| Pik3c2g |
A |
C |
6: 139,789,768 (GRCm39) |
K304Q |
probably damaging |
Het |
| Pkd2 |
T |
A |
5: 104,634,672 (GRCm39) |
W568R |
probably damaging |
Het |
| Pld2 |
T |
A |
11: 70,435,010 (GRCm39) |
I306N |
probably damaging |
Het |
| Plppr3 |
T |
C |
10: 79,709,903 (GRCm39) |
K9R |
probably damaging |
Het |
| Pramel11 |
T |
A |
4: 143,622,061 (GRCm39) |
R431S |
possibly damaging |
Het |
| Psme4 |
T |
C |
11: 30,760,922 (GRCm39) |
V397A |
probably damaging |
Het |
| Ptbp2 |
A |
T |
3: 119,555,398 (GRCm39) |
S23R |
probably damaging |
Het |
| Ptpn13 |
A |
G |
5: 103,728,575 (GRCm39) |
D2074G |
probably null |
Het |
| Rab34 |
T |
A |
11: 78,082,081 (GRCm39) |
L166H |
probably damaging |
Het |
| Rabgap1l |
T |
A |
1: 160,472,880 (GRCm39) |
R519S |
probably benign |
Het |
| Rasa1 |
A |
T |
13: 85,374,691 (GRCm39) |
L218* |
probably null |
Het |
| Reln |
A |
G |
5: 22,249,960 (GRCm39) |
|
probably null |
Het |
| Rer1 |
T |
C |
4: 155,162,956 (GRCm39) |
D94G |
possibly damaging |
Het |
| Rhpn1 |
T |
C |
15: 75,583,673 (GRCm39) |
V386A |
probably benign |
Het |
| Samd3 |
T |
A |
10: 26,147,754 (GRCm39) |
C476* |
probably null |
Het |
| Sdk2 |
C |
T |
11: 113,729,472 (GRCm39) |
|
silent |
Het |
| Sipa1l3 |
A |
G |
7: 29,038,592 (GRCm39) |
S352P |
possibly damaging |
Het |
| Slc27a2 |
A |
G |
2: 126,428,262 (GRCm39) |
Y549C |
probably benign |
Het |
| Slc7a9 |
A |
G |
7: 35,149,279 (GRCm39) |
T7A |
probably benign |
Het |
| Slco4c1 |
C |
T |
1: 96,770,224 (GRCm39) |
G280D |
probably damaging |
Het |
| Snx19 |
T |
A |
9: 30,344,872 (GRCm39) |
V657E |
probably damaging |
Het |
| Spata31d1c |
A |
G |
13: 65,183,690 (GRCm39) |
M411V |
probably benign |
Het |
| Spice1 |
T |
A |
16: 44,178,193 (GRCm39) |
L72* |
probably null |
Het |
| Stard9 |
G |
T |
2: 120,544,293 (GRCm39) |
V4471L |
probably damaging |
Het |
| Syt14 |
A |
G |
1: 192,584,143 (GRCm39) |
L707P |
probably damaging |
Het |
| Tab1 |
T |
C |
15: 80,037,869 (GRCm39) |
I234T |
probably damaging |
Het |
| Tas2r107 |
T |
C |
6: 131,636,951 (GRCm39) |
M33V |
probably benign |
Het |
| Tbx4 |
T |
A |
11: 85,805,349 (GRCm39) |
S479R |
possibly damaging |
Het |
| Tssk5 |
C |
T |
15: 76,257,093 (GRCm39) |
R263Q |
probably benign |
Het |
| Ttn |
T |
C |
2: 76,701,200 (GRCm39) |
|
probably benign |
Het |
| Ugt2b5 |
T |
A |
5: 87,287,489 (GRCm39) |
Q226L |
probably benign |
Het |
| Ush2a |
C |
T |
1: 188,447,261 (GRCm39) |
S2483L |
probably benign |
Het |
| Wdr95 |
A |
G |
5: 149,475,891 (GRCm39) |
Y63C |
probably damaging |
Het |
| Xirp2 |
A |
G |
2: 67,346,700 (GRCm39) |
I2980M |
probably damaging |
Het |
| Yeats4 |
G |
A |
10: 117,051,636 (GRCm39) |
T207I |
probably benign |
Het |
| Ythdc1 |
A |
G |
5: 86,978,489 (GRCm39) |
R561G |
probably damaging |
Het |
| Zbtb14 |
G |
A |
17: 69,694,385 (GRCm39) |
E28K |
possibly damaging |
Het |
| Zfp931 |
A |
T |
2: 177,711,684 (GRCm39) |
L21Q |
probably damaging |
Het |
| Zyg11b |
A |
C |
4: 108,112,423 (GRCm39) |
M415R |
probably damaging |
Het |
|
| Other mutations in Dscaml1 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00418:Dscaml1
|
APN |
9 |
45,581,498 (GRCm39) |
nonsense |
probably null |
|
|
IGL00497:Dscaml1
|
APN |
9 |
45,663,536 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL00895:Dscaml1
|
APN |
9 |
45,662,551 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL01011:Dscaml1
|
APN |
9 |
45,594,970 (GRCm39) |
missense |
possibly damaging |
0.76 |
|
IGL01086:Dscaml1
|
APN |
9 |
45,613,960 (GRCm39) |
splice site |
probably benign |
|
|
IGL01125:Dscaml1
|
APN |
9 |
45,660,930 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
IGL01132:Dscaml1
|
APN |
9 |
45,663,626 (GRCm39) |
nonsense |
probably null |
|
|
IGL01356:Dscaml1
|
APN |
9 |
45,658,155 (GRCm39) |
missense |
probably benign |
0.03 |
|
IGL01459:Dscaml1
|
APN |
9 |
45,653,981 (GRCm39) |
nonsense |
probably null |
|
|
IGL01552:Dscaml1
|
APN |
9 |
45,359,206 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02033:Dscaml1
|
APN |
9 |
45,595,080 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02044:Dscaml1
|
APN |
9 |
45,658,241 (GRCm39) |
nonsense |
probably null |
|
|
IGL02095:Dscaml1
|
APN |
9 |
45,359,001 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02166:Dscaml1
|
APN |
9 |
45,594,999 (GRCm39) |
missense |
probably damaging |
0.98 |
|
IGL02262:Dscaml1
|
APN |
9 |
45,643,378 (GRCm39) |
missense |
probably benign |
0.44 |
|
IGL02262:Dscaml1
|
APN |
9 |
45,656,414 (GRCm39) |
missense |
probably benign |
|
|
IGL02340:Dscaml1
|
APN |
9 |
45,581,474 (GRCm39) |
missense |
possibly damaging |
0.66 |
|
IGL02604:Dscaml1
|
APN |
9 |
45,655,626 (GRCm39) |
unclassified |
probably benign |
|
|
IGL02619:Dscaml1
|
APN |
9 |
45,359,094 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02805:Dscaml1
|
APN |
9 |
45,359,195 (GRCm39) |
missense |
probably damaging |
0.98 |
|
IGL03409:Dscaml1
|
APN |
9 |
45,581,401 (GRCm39) |
missense |
probably damaging |
1.00 |
|
D3080:Dscaml1
|
UTSW |
9 |
45,595,623 (GRCm39) |
missense |
probably benign |
0.44 |
|
IGL03050:Dscaml1
|
UTSW |
9 |
45,654,297 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0149:Dscaml1
|
UTSW |
9 |
45,653,978 (GRCm39) |
nonsense |
probably null |
|
|
R0582:Dscaml1
|
UTSW |
9 |
45,579,562 (GRCm39) |
missense |
possibly damaging |
0.77 |
|
R0629:Dscaml1
|
UTSW |
9 |
45,632,716 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R0632:Dscaml1
|
UTSW |
9 |
45,643,432 (GRCm39) |
missense |
probably benign |
0.06 |
|
R0815:Dscaml1
|
UTSW |
9 |
45,656,372 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1162:Dscaml1
|
UTSW |
9 |
45,663,647 (GRCm39) |
splice site |
probably benign |
|
|
R1449:Dscaml1
|
UTSW |
9 |
45,653,521 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R1474:Dscaml1
|
UTSW |
9 |
45,596,519 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1481:Dscaml1
|
UTSW |
9 |
45,583,941 (GRCm39) |
missense |
probably benign |
0.01 |
|
R1533:Dscaml1
|
UTSW |
9 |
45,361,882 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1542:Dscaml1
|
UTSW |
9 |
45,660,738 (GRCm39) |
missense |
possibly damaging |
0.84 |
|
R1572:Dscaml1
|
UTSW |
9 |
45,632,631 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1627:Dscaml1
|
UTSW |
9 |
45,664,445 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1634:Dscaml1
|
UTSW |
9 |
45,584,047 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1713:Dscaml1
|
UTSW |
9 |
45,663,988 (GRCm39) |
missense |
possibly damaging |
0.49 |
|
R1777:Dscaml1
|
UTSW |
9 |
45,595,054 (GRCm39) |
missense |
possibly damaging |
0.58 |
|
R1812:Dscaml1
|
UTSW |
9 |
45,662,584 (GRCm39) |
critical splice donor site |
probably null |
|
|
R1834:Dscaml1
|
UTSW |
9 |
45,594,930 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1953:Dscaml1
|
UTSW |
9 |
45,581,522 (GRCm39) |
missense |
probably benign |
0.01 |
|
R2056:Dscaml1
|
UTSW |
9 |
45,661,430 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R2193:Dscaml1
|
UTSW |
9 |
45,596,532 (GRCm39) |
missense |
probably benign |
0.21 |
|
R2497:Dscaml1
|
UTSW |
9 |
45,656,376 (GRCm39) |
missense |
probably benign |
0.00 |
|
R3768:Dscaml1
|
UTSW |
9 |
45,643,435 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R3891:Dscaml1
|
UTSW |
9 |
45,628,782 (GRCm39) |
missense |
possibly damaging |
0.84 |
|
R4110:Dscaml1
|
UTSW |
9 |
45,643,366 (GRCm39) |
missense |
probably benign |
0.07 |
|
R4706:Dscaml1
|
UTSW |
9 |
45,361,878 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4716:Dscaml1
|
UTSW |
9 |
45,361,890 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4719:Dscaml1
|
UTSW |
9 |
45,583,993 (GRCm39) |
missense |
probably benign |
0.13 |
|
R4770:Dscaml1
|
UTSW |
9 |
45,581,404 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4924:Dscaml1
|
UTSW |
9 |
45,656,487 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5167:Dscaml1
|
UTSW |
9 |
45,628,730 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5346:Dscaml1
|
UTSW |
9 |
45,361,857 (GRCm39) |
missense |
possibly damaging |
0.63 |
|
R5737:Dscaml1
|
UTSW |
9 |
45,656,483 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5977:Dscaml1
|
UTSW |
9 |
45,632,596 (GRCm39) |
missense |
probably benign |
0.19 |
|
R6073:Dscaml1
|
UTSW |
9 |
45,361,881 (GRCm39) |
missense |
probably benign |
0.22 |
|
R6276:Dscaml1
|
UTSW |
9 |
45,579,458 (GRCm39) |
missense |
possibly damaging |
0.62 |
|
R6415:Dscaml1
|
UTSW |
9 |
45,594,975 (GRCm39) |
nonsense |
probably null |
|
|
R6527:Dscaml1
|
UTSW |
9 |
45,623,482 (GRCm39) |
nonsense |
probably null |
|
|
R6582:Dscaml1
|
UTSW |
9 |
45,664,104 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6655:Dscaml1
|
UTSW |
9 |
45,658,235 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6772:Dscaml1
|
UTSW |
9 |
45,621,609 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6799:Dscaml1
|
UTSW |
9 |
45,361,881 (GRCm39) |
missense |
probably benign |
0.22 |
|
R6892:Dscaml1
|
UTSW |
9 |
45,595,128 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6918:Dscaml1
|
UTSW |
9 |
45,341,805 (GRCm39) |
missense |
probably benign |
|
|
R6967:Dscaml1
|
UTSW |
9 |
45,585,821 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R7214:Dscaml1
|
UTSW |
9 |
45,581,437 (GRCm39) |
missense |
probably benign |
0.01 |
|
R7286:Dscaml1
|
UTSW |
9 |
45,654,044 (GRCm39) |
critical splice donor site |
probably null |
|
|
R7315:Dscaml1
|
UTSW |
9 |
45,656,423 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7338:Dscaml1
|
UTSW |
9 |
45,585,802 (GRCm39) |
missense |
probably benign |
0.12 |
|
R7343:Dscaml1
|
UTSW |
9 |
45,664,214 (GRCm39) |
missense |
probably benign |
|
|
R7395:Dscaml1
|
UTSW |
9 |
45,613,703 (GRCm39) |
missense |
possibly damaging |
0.73 |
|
R7439:Dscaml1
|
UTSW |
9 |
45,621,624 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R7484:Dscaml1
|
UTSW |
9 |
45,660,744 (GRCm39) |
splice site |
probably null |
|
|
R7545:Dscaml1
|
UTSW |
9 |
45,596,681 (GRCm39) |
missense |
probably benign |
0.11 |
|
R7979:Dscaml1
|
UTSW |
9 |
45,595,029 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8005:Dscaml1
|
UTSW |
9 |
45,628,808 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8181:Dscaml1
|
UTSW |
9 |
45,658,140 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
R8262:Dscaml1
|
UTSW |
9 |
45,658,438 (GRCm39) |
intron |
probably benign |
|
|
R8428:Dscaml1
|
UTSW |
9 |
45,653,884 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8725:Dscaml1
|
UTSW |
9 |
45,341,759 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8727:Dscaml1
|
UTSW |
9 |
45,341,759 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8796:Dscaml1
|
UTSW |
9 |
45,359,026 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8840:Dscaml1
|
UTSW |
9 |
45,634,718 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9291:Dscaml1
|
UTSW |
9 |
45,359,251 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9394:Dscaml1
|
UTSW |
9 |
45,661,354 (GRCm39) |
missense |
possibly damaging |
0.64 |
|
R9610:Dscaml1
|
UTSW |
9 |
45,579,522 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R9611:Dscaml1
|
UTSW |
9 |
45,579,522 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R9653:Dscaml1
|
UTSW |
9 |
45,643,466 (GRCm39) |
critical splice donor site |
probably null |
|
|
R9699:Dscaml1
|
UTSW |
9 |
45,654,315 (GRCm39) |
missense |
probably damaging |
0.97 |
|
X0058:Dscaml1
|
UTSW |
9 |
45,663,426 (GRCm39) |
missense |
probably benign |
0.00 |
|
Z1177:Dscaml1
|
UTSW |
9 |
45,584,089 (GRCm39) |
missense |
probably damaging |
0.98 |
|
| Predicted Primers |
PCR Primer
(F):5'- ACTGCAGGACTAGCTCCATC -3'
(R):5'- AGGAGCCAGAATTCTGCAAATG -3'
Sequencing Primer
(F):5'- ATCAGCTCCCGGGGTTGAG -3'
(R):5'- TGGAAGCTTCTATCAGACCCTAGG -3'
|
| Posted On |
2014-07-14 |
Incidental Mutation