Incidental Mutation 'R1933:Foxp1'
| ID |
215558 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Foxp1
|
| Ensembl Gene |
ENSMUSG00000030067 |
| Gene Name |
forkhead box P1 |
| Synonyms |
3110052D19Rik, 4932443N09Rik |
| MMRRC Submission |
039951-MU
|
| Accession Numbers |
|
| Essential gene? |
Essential
(E-score: 1.000)
|
| Stock # |
R1933 (G1)
|
| Quality Score |
150 |
|
Status
|
Not validated
|
| Chromosome |
6 |
| Chromosomal Location |
98902299-99499682 bp(-) (GRCm39) |
| Type of Mutation |
small deletion (1 aa in frame mutation) |
| DNA Base Change (assembly) |
TTGCTGCTGCTGCTGCTGCTGCTGTTGCTGCTGCTGCTGTTGCTGCTGCTG to TTGCTGCTGCTGCTGCTGCTGTTGCTGCTGCTGCTGTTGCTGCTGCTG
at 99052926 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000135764
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000074346]
[ENSMUST00000113322]
[ENSMUST00000113324]
[ENSMUST00000113326]
[ENSMUST00000113328]
[ENSMUST00000113329]
[ENSMUST00000175886]
[ENSMUST00000176565]
[ENSMUST00000177208]
[ENSMUST00000177307]
[ENSMUST00000177230]
[ENSMUST00000176632]
[ENSMUST00000176850]
|
| AlphaFold |
P58462 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000074346
|
| SMART Domains |
Protein: ENSMUSP00000073953
Gene: ENSMUSG00000030067
| Domain | Start | End | E-Value | Type |
|---|
|
coiled coil region
|
62 |
113 |
N/A |
INTRINSIC |
|
low complexity region
|
140 |
191 |
N/A |
INTRINSIC |
|
low complexity region
|
200 |
233 |
N/A |
INTRINSIC |
|
low complexity region
|
236 |
250 |
N/A |
INTRINSIC |
|
low complexity region
|
264 |
275 |
N/A |
INTRINSIC |
|
low complexity region
|
317 |
330 |
N/A |
INTRINSIC |
|
ZnF_C2H2
|
334 |
359 |
8.67e-1 |
SMART |
|
low complexity region
|
371 |
383 |
N/A |
INTRINSIC |
|
low complexity region
|
432 |
446 |
N/A |
INTRINSIC |
|
FH
|
491 |
572 |
2.07e-39 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000113322
|
| SMART Domains |
Protein: ENSMUSP00000108948
Gene: ENSMUSG00000030067
| Domain | Start | End | E-Value | Type |
|---|
|
coiled coil region
|
62 |
113 |
N/A |
INTRINSIC |
|
low complexity region
|
140 |
191 |
N/A |
INTRINSIC |
|
low complexity region
|
200 |
233 |
N/A |
INTRINSIC |
|
low complexity region
|
236 |
250 |
N/A |
INTRINSIC |
|
low complexity region
|
264 |
275 |
N/A |
INTRINSIC |
|
low complexity region
|
317 |
330 |
N/A |
INTRINSIC |
|
ZnF_C2H2
|
334 |
359 |
8.67e-1 |
SMART |
|
low complexity region
|
371 |
383 |
N/A |
INTRINSIC |
|
low complexity region
|
432 |
446 |
N/A |
INTRINSIC |
|
FH
|
491 |
572 |
2.07e-39 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000113324
|
| SMART Domains |
Protein: ENSMUSP00000108950
Gene: ENSMUSG00000030067
| Domain | Start | End | E-Value | Type |
|---|
|
coiled coil region
|
62 |
113 |
N/A |
INTRINSIC |
|
low complexity region
|
140 |
192 |
N/A |
INTRINSIC |
|
low complexity region
|
201 |
234 |
N/A |
INTRINSIC |
|
low complexity region
|
237 |
251 |
N/A |
INTRINSIC |
|
low complexity region
|
265 |
276 |
N/A |
INTRINSIC |
|
low complexity region
|
318 |
331 |
N/A |
INTRINSIC |
|
ZnF_C2H2
|
335 |
360 |
8.67e-1 |
SMART |
|
low complexity region
|
372 |
384 |
N/A |
INTRINSIC |
|
low complexity region
|
433 |
447 |
N/A |
INTRINSIC |
|
FH
|
492 |
573 |
2.07e-39 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000113326
|
| SMART Domains |
Protein: ENSMUSP00000108952
Gene: ENSMUSG00000030067
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
108 |
159 |
N/A |
INTRINSIC |
|
low complexity region
|
168 |
201 |
N/A |
INTRINSIC |
|
low complexity region
|
204 |
218 |
N/A |
INTRINSIC |
|
low complexity region
|
232 |
243 |
N/A |
INTRINSIC |
|
low complexity region
|
285 |
298 |
N/A |
INTRINSIC |
|
ZnF_C2H2
|
302 |
327 |
8.67e-1 |
SMART |
|
low complexity region
|
339 |
351 |
N/A |
INTRINSIC |
|
low complexity region
|
400 |
414 |
N/A |
INTRINSIC |
|
FH
|
459 |
540 |
2.07e-39 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000113328
|
| SMART Domains |
Protein: ENSMUSP00000108954
Gene: ENSMUSG00000030067
| Domain | Start | End | E-Value | Type |
|---|
|
coiled coil region
|
62 |
113 |
N/A |
INTRINSIC |
|
low complexity region
|
140 |
191 |
N/A |
INTRINSIC |
|
low complexity region
|
200 |
234 |
N/A |
INTRINSIC |
|
low complexity region
|
237 |
251 |
N/A |
INTRINSIC |
|
low complexity region
|
265 |
276 |
N/A |
INTRINSIC |
|
low complexity region
|
318 |
331 |
N/A |
INTRINSIC |
|
ZnF_C2H2
|
335 |
360 |
8.67e-1 |
SMART |
|
low complexity region
|
372 |
384 |
N/A |
INTRINSIC |
|
low complexity region
|
433 |
447 |
N/A |
INTRINSIC |
|
FH
|
492 |
573 |
2.07e-39 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000113329
|
| SMART Domains |
Protein: ENSMUSP00000108955
Gene: ENSMUSG00000030067
| Domain | Start | End | E-Value | Type |
|---|
|
coiled coil region
|
62 |
113 |
N/A |
INTRINSIC |
|
low complexity region
|
140 |
191 |
N/A |
INTRINSIC |
|
low complexity region
|
200 |
233 |
N/A |
INTRINSIC |
|
low complexity region
|
236 |
250 |
N/A |
INTRINSIC |
|
low complexity region
|
264 |
275 |
N/A |
INTRINSIC |
|
low complexity region
|
317 |
330 |
N/A |
INTRINSIC |
|
ZnF_C2H2
|
334 |
359 |
8.67e-1 |
SMART |
|
low complexity region
|
371 |
383 |
N/A |
INTRINSIC |
|
low complexity region
|
432 |
446 |
N/A |
INTRINSIC |
|
FH
|
491 |
579 |
1.76e-10 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000175886
|
| SMART Domains |
Protein: ENSMUSP00000135517
Gene: ENSMUSG00000030067
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
10 |
62 |
N/A |
INTRINSIC |
|
low complexity region
|
71 |
105 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000176565
|
| SMART Domains |
Protein: ENSMUSP00000135181
Gene: ENSMUSG00000030067
| Domain | Start | End | E-Value | Type |
|---|
|
coiled coil region
|
62 |
113 |
N/A |
INTRINSIC |
|
low complexity region
|
140 |
191 |
N/A |
INTRINSIC |
|
low complexity region
|
200 |
234 |
N/A |
INTRINSIC |
|
low complexity region
|
237 |
251 |
N/A |
INTRINSIC |
|
low complexity region
|
265 |
276 |
N/A |
INTRINSIC |
|
low complexity region
|
318 |
331 |
N/A |
INTRINSIC |
|
ZnF_C2H2
|
335 |
360 |
8.67e-1 |
SMART |
|
low complexity region
|
372 |
384 |
N/A |
INTRINSIC |
|
low complexity region
|
433 |
447 |
N/A |
INTRINSIC |
|
FH
|
491 |
572 |
2.07e-39 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000177208
|
| SMART Domains |
Protein: ENSMUSP00000135187
Gene: ENSMUSG00000030067
| Domain | Start | End | E-Value | Type |
|---|
|
coiled coil region
|
62 |
88 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000177307
|
| SMART Domains |
Protein: ENSMUSP00000135764
Gene: ENSMUSG00000030067
| Domain | Start | End | E-Value | Type |
|---|
|
coiled coil region
|
62 |
113 |
N/A |
INTRINSIC |
|
low complexity region
|
140 |
192 |
N/A |
INTRINSIC |
|
low complexity region
|
201 |
235 |
N/A |
INTRINSIC |
|
low complexity region
|
238 |
252 |
N/A |
INTRINSIC |
|
low complexity region
|
266 |
277 |
N/A |
INTRINSIC |
|
low complexity region
|
319 |
332 |
N/A |
INTRINSIC |
|
ZnF_C2H2
|
336 |
361 |
8.67e-1 |
SMART |
|
low complexity region
|
373 |
385 |
N/A |
INTRINSIC |
|
low complexity region
|
434 |
448 |
N/A |
INTRINSIC |
|
FH
|
492 |
573 |
2.07e-39 |
SMART |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000200105
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000177230
|
| SMART Domains |
Protein: ENSMUSP00000135098
Gene: ENSMUSG00000030067
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
108 |
160 |
N/A |
INTRINSIC |
|
low complexity region
|
169 |
203 |
N/A |
INTRINSIC |
|
low complexity region
|
206 |
220 |
N/A |
INTRINSIC |
|
low complexity region
|
234 |
245 |
N/A |
INTRINSIC |
|
low complexity region
|
287 |
300 |
N/A |
INTRINSIC |
|
ZnF_C2H2
|
304 |
329 |
8.67e-1 |
SMART |
|
low complexity region
|
341 |
353 |
N/A |
INTRINSIC |
|
low complexity region
|
402 |
416 |
N/A |
INTRINSIC |
|
FH
|
461 |
542 |
2.07e-39 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000176632
|
| SMART Domains |
Protein: ENSMUSP00000135635
Gene: ENSMUSG00000030067
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
108 |
159 |
N/A |
INTRINSIC |
|
low complexity region
|
168 |
202 |
N/A |
INTRINSIC |
|
low complexity region
|
205 |
219 |
N/A |
INTRINSIC |
|
low complexity region
|
233 |
244 |
N/A |
INTRINSIC |
|
low complexity region
|
286 |
299 |
N/A |
INTRINSIC |
|
ZnF_C2H2
|
303 |
328 |
8.67e-1 |
SMART |
|
low complexity region
|
340 |
352 |
N/A |
INTRINSIC |
|
low complexity region
|
401 |
415 |
N/A |
INTRINSIC |
|
FH
|
460 |
541 |
2.07e-39 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000176850
|
| SMART Domains |
Protein: ENSMUSP00000135041
Gene: ENSMUSG00000030067
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
108 |
160 |
N/A |
INTRINSIC |
|
low complexity region
|
169 |
203 |
N/A |
INTRINSIC |
|
low complexity region
|
206 |
220 |
N/A |
INTRINSIC |
|
low complexity region
|
234 |
245 |
N/A |
INTRINSIC |
|
low complexity region
|
287 |
300 |
N/A |
INTRINSIC |
|
ZnF_C2H2
|
304 |
329 |
8.67e-1 |
SMART |
|
low complexity region
|
341 |
353 |
N/A |
INTRINSIC |
|
low complexity region
|
402 |
416 |
N/A |
INTRINSIC |
|
FH
|
461 |
542 |
2.07e-39 |
SMART |
|
| Coding Region Coverage |
- 1x: 97.5%
- 3x: 97.0%
- 10x: 95.7%
- 20x: 93.4%
|
| Validation Efficiency |
|
| MGI Phenotype |
PHENOTYPE: Homozygous null mice display embryonic lethality with abnormal outflow tract septation, ventricular septal defects, abnormal cardiac valve morphology, decreased and irregular heart rate, thin ventricular compact zone, and edema. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 78 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Adam25 |
A |
T |
8: 41,207,922 (GRCm39) |
Y396F |
probably benign |
Het |
| Adra2a |
T |
A |
19: 54,034,837 (GRCm39) |
F64L |
probably damaging |
Het |
| Ankrd45 |
A |
T |
1: 160,978,870 (GRCm39) |
N103I |
probably damaging |
Het |
| Arhgef7 |
C |
A |
8: 11,858,713 (GRCm39) |
|
probably null |
Het |
| Bsn |
A |
G |
9: 107,993,643 (GRCm39) |
V703A |
possibly damaging |
Het |
| Btaf1 |
T |
A |
19: 36,950,357 (GRCm39) |
I529K |
probably damaging |
Het |
| Ccdc110 |
A |
G |
8: 46,396,287 (GRCm39) |
N726S |
probably damaging |
Het |
| Ccdc78 |
T |
A |
17: 26,006,044 (GRCm39) |
S71T |
probably damaging |
Het |
| Cct5 |
G |
T |
15: 31,591,154 (GRCm39) |
Q516K |
probably benign |
Het |
| Cd300c2 |
A |
T |
11: 114,891,685 (GRCm39) |
V63E |
probably benign |
Het |
| Cdh16 |
A |
G |
8: 105,344,595 (GRCm39) |
V7A |
possibly damaging |
Het |
| Clec16a |
T |
C |
16: 10,506,403 (GRCm39) |
F710L |
probably damaging |
Het |
| Clpb |
T |
G |
7: 101,428,418 (GRCm39) |
F393V |
probably damaging |
Het |
| Commd9 |
G |
A |
2: 101,731,376 (GRCm39) |
R187H |
probably damaging |
Het |
| Crx |
T |
A |
7: 15,602,301 (GRCm39) |
K126* |
probably null |
Het |
| Dcaf13 |
T |
A |
15: 39,001,483 (GRCm39) |
Y264N |
probably damaging |
Het |
| Dnah12 |
T |
A |
14: 26,455,650 (GRCm39) |
I791N |
probably damaging |
Het |
| Dpy19l1 |
A |
T |
9: 24,345,683 (GRCm39) |
D456E |
probably damaging |
Het |
| Dscam |
A |
G |
16: 96,394,414 (GRCm39) |
S1963P |
probably benign |
Het |
| Efl1 |
C |
T |
7: 82,412,325 (GRCm39) |
Q905* |
probably null |
Het |
| Farsa |
T |
C |
8: 85,587,780 (GRCm39) |
F104L |
probably benign |
Het |
| Fbxl19 |
C |
A |
7: 127,350,101 (GRCm39) |
A231E |
probably benign |
Het |
| Fbxw19 |
A |
T |
9: 109,310,718 (GRCm39) |
N401K |
probably benign |
Het |
| Frem3 |
A |
G |
8: 81,339,519 (GRCm39) |
N604S |
probably benign |
Het |
| Gad1 |
T |
G |
2: 70,417,736 (GRCm39) |
C312G |
possibly damaging |
Het |
| Garem2 |
G |
T |
5: 30,319,860 (GRCm39) |
E441* |
probably null |
Het |
| Glra3 |
G |
T |
8: 56,393,942 (GRCm39) |
A18S |
probably benign |
Het |
| Gm8206 |
A |
T |
14: 6,022,475 (GRCm38) |
M8K |
probably benign |
Het |
| Gpr162 |
G |
A |
6: 124,838,410 (GRCm39) |
S80F |
probably damaging |
Het |
| Grpr |
C |
A |
X: 162,332,137 (GRCm39) |
V53L |
probably benign |
Het |
| Il21 |
C |
T |
3: 37,286,635 (GRCm39) |
R27H |
probably benign |
Het |
| Il21r |
C |
T |
7: 125,228,153 (GRCm39) |
T208I |
possibly damaging |
Het |
| Kcnab2 |
T |
C |
4: 152,520,323 (GRCm39) |
T6A |
possibly damaging |
Het |
| Klra4 |
T |
A |
6: 130,042,207 (GRCm39) |
Q20L |
possibly damaging |
Het |
| Lrrtm1 |
A |
T |
6: 77,221,949 (GRCm39) |
|
probably null |
Het |
| Lrrtm3 |
A |
G |
10: 63,924,292 (GRCm39) |
F292L |
possibly damaging |
Het |
| Mpeg1 |
A |
T |
19: 12,440,011 (GRCm39) |
K490* |
probably null |
Het |
| Myh14 |
C |
T |
7: 44,264,772 (GRCm39) |
M1671I |
probably benign |
Het |
| Nebl |
A |
T |
2: 17,380,103 (GRCm39) |
M757K |
probably damaging |
Het |
| Or51m1 |
G |
T |
7: 103,578,337 (GRCm39) |
M102I |
probably damaging |
Het |
| Or56b1b |
A |
C |
7: 108,164,730 (GRCm39) |
F91V |
possibly damaging |
Het |
| Or5aq1 |
T |
A |
2: 86,966,188 (GRCm39) |
H159L |
probably damaging |
Het |
| Pkhd1l1 |
A |
T |
15: 44,404,280 (GRCm39) |
H2303L |
possibly damaging |
Het |
| Podxl2 |
C |
T |
6: 88,826,587 (GRCm39) |
V240M |
probably benign |
Het |
| Ppp2r5e |
C |
G |
12: 75,516,341 (GRCm39) |
A239P |
probably damaging |
Het |
| Prss53 |
T |
C |
7: 127,485,434 (GRCm39) |
*553W |
probably null |
Het |
| Psma3 |
T |
A |
12: 71,031,468 (GRCm39) |
M43K |
probably benign |
Het |
| Rad50 |
G |
T |
11: 53,570,888 (GRCm39) |
T790K |
probably benign |
Het |
| Rasgrf1 |
G |
T |
9: 89,835,966 (GRCm39) |
Q231H |
probably damaging |
Het |
| Rpn1 |
T |
A |
6: 88,070,841 (GRCm39) |
V237E |
probably damaging |
Het |
| Scn10a |
T |
A |
9: 119,439,064 (GRCm39) |
M1601L |
probably damaging |
Het |
| Sema4f |
G |
T |
6: 82,907,908 (GRCm39) |
P180Q |
probably damaging |
Het |
| Serpinb5 |
A |
G |
1: 106,803,851 (GRCm39) |
E8G |
probably damaging |
Het |
| Sgcg |
C |
T |
14: 61,469,861 (GRCm39) |
V167I |
possibly damaging |
Het |
| Slc25a13 |
C |
T |
6: 6,109,262 (GRCm39) |
V367M |
probably damaging |
Het |
| Spata31 |
T |
C |
13: 65,068,424 (GRCm39) |
S191P |
probably benign |
Het |
| Srbd1 |
A |
G |
17: 86,410,321 (GRCm39) |
V537A |
probably damaging |
Het |
| Srgap1 |
G |
T |
10: 121,761,808 (GRCm39) |
D113E |
possibly damaging |
Het |
| Srl |
A |
G |
16: 4,310,214 (GRCm39) |
I505T |
probably damaging |
Het |
| St14 |
G |
A |
9: 31,017,508 (GRCm39) |
T226I |
probably benign |
Het |
| Stard9 |
T |
A |
2: 120,529,137 (GRCm39) |
I1798N |
possibly damaging |
Het |
| Sugp1 |
A |
G |
8: 70,509,225 (GRCm39) |
E166G |
possibly damaging |
Het |
| Susd1 |
A |
T |
4: 59,351,695 (GRCm39) |
N455K |
possibly damaging |
Het |
| Sytl3 |
T |
A |
17: 7,000,445 (GRCm39) |
V205E |
probably damaging |
Het |
| Tenm4 |
A |
G |
7: 96,544,533 (GRCm39) |
Y2183C |
probably damaging |
Het |
| Tktl2 |
G |
A |
8: 66,964,999 (GRCm39) |
V186M |
probably damaging |
Het |
| Tlcd3b |
T |
A |
7: 126,426,844 (GRCm39) |
|
probably null |
Het |
| Tlr1 |
T |
G |
5: 65,082,781 (GRCm39) |
T599P |
possibly damaging |
Het |
| Trpc6 |
G |
A |
9: 8,656,546 (GRCm39) |
D658N |
probably damaging |
Het |
| Ttc39b |
A |
G |
4: 83,150,957 (GRCm39) |
V546A |
possibly damaging |
Het |
| Ube3c |
T |
C |
5: 29,824,657 (GRCm39) |
Y561H |
probably damaging |
Het |
| Vmn1r29 |
T |
A |
6: 58,284,405 (GRCm39) |
S42T |
probably benign |
Het |
| Vps4a |
T |
C |
8: 107,771,190 (GRCm39) |
V392A |
probably benign |
Het |
| Wdfy4 |
T |
C |
14: 32,855,301 (GRCm39) |
E771G |
probably benign |
Het |
| Whrn |
G |
A |
4: 63,333,876 (GRCm39) |
Q415* |
probably null |
Het |
| Wnt5a |
C |
T |
14: 28,233,802 (GRCm39) |
P10L |
probably benign |
Het |
| Zfhx2 |
T |
C |
14: 55,312,695 (GRCm39) |
|
probably benign |
Het |
| Zfp451 |
T |
C |
1: 33,816,903 (GRCm39) |
K132R |
probably damaging |
Het |
|
| Other mutations in Foxp1 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL02191:Foxp1
|
APN |
6 |
98,922,561 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL02330:Foxp1
|
APN |
6 |
98,922,373 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02869:Foxp1
|
APN |
6 |
98,907,044 (GRCm39) |
utr 3 prime |
probably benign |
|
|
IGL02968:Foxp1
|
APN |
6 |
99,052,822 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Foxy
|
UTSW |
6 |
98,992,471 (GRCm39) |
nonsense |
probably null |
|
|
Moxie
|
UTSW |
6 |
98,992,475 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
Roxie
|
UTSW |
6 |
98,918,595 (GRCm39) |
missense |
unknown |
|
|
R0037:Foxp1
|
UTSW |
6 |
99,139,930 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0063:Foxp1
|
UTSW |
6 |
98,921,684 (GRCm39) |
splice site |
probably benign |
|
|
R0063:Foxp1
|
UTSW |
6 |
98,921,684 (GRCm39) |
splice site |
probably benign |
|
|
R0427:Foxp1
|
UTSW |
6 |
98,907,164 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0601:Foxp1
|
UTSW |
6 |
98,907,083 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1356:Foxp1
|
UTSW |
6 |
98,993,637 (GRCm39) |
splice site |
probably benign |
|
|
R1468:Foxp1
|
UTSW |
6 |
98,955,181 (GRCm39) |
missense |
possibly damaging |
0.62 |
|
R1468:Foxp1
|
UTSW |
6 |
98,955,181 (GRCm39) |
missense |
possibly damaging |
0.62 |
|
R1548:Foxp1
|
UTSW |
6 |
98,922,381 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1696:Foxp1
|
UTSW |
6 |
98,922,663 (GRCm39) |
missense |
probably benign |
0.18 |
|
R2152:Foxp1
|
UTSW |
6 |
98,993,502 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R2338:Foxp1
|
UTSW |
6 |
98,980,254 (GRCm39) |
missense |
possibly damaging |
0.61 |
|
R3896:Foxp1
|
UTSW |
6 |
99,052,897 (GRCm39) |
missense |
probably benign |
0.33 |
|
R5006:Foxp1
|
UTSW |
6 |
99,139,819 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R5143:Foxp1
|
UTSW |
6 |
98,922,493 (GRCm39) |
critical splice donor site |
probably null |
|
|
R5428:Foxp1
|
UTSW |
6 |
98,993,592 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5765:Foxp1
|
UTSW |
6 |
98,992,423 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5816:Foxp1
|
UTSW |
6 |
99,052,926 (GRCm39) |
small deletion |
probably benign |
|
|
R6172:Foxp1
|
UTSW |
6 |
98,992,475 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R6172:Foxp1
|
UTSW |
6 |
98,992,471 (GRCm39) |
nonsense |
probably null |
|
|
R6173:Foxp1
|
UTSW |
6 |
98,992,475 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R6173:Foxp1
|
UTSW |
6 |
98,992,471 (GRCm39) |
nonsense |
probably null |
|
|
R6175:Foxp1
|
UTSW |
6 |
98,943,037 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6776:Foxp1
|
UTSW |
6 |
99,052,926 (GRCm39) |
small deletion |
probably benign |
|
|
R6782:Foxp1
|
UTSW |
6 |
98,907,106 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7229:Foxp1
|
UTSW |
6 |
98,912,373 (GRCm39) |
missense |
unknown |
|
|
R7559:Foxp1
|
UTSW |
6 |
98,922,521 (GRCm39) |
missense |
unknown |
|
|
R7715:Foxp1
|
UTSW |
6 |
98,922,621 (GRCm39) |
missense |
unknown |
|
|
R8007:Foxp1
|
UTSW |
6 |
98,918,595 (GRCm39) |
missense |
unknown |
|
|
R8099:Foxp1
|
UTSW |
6 |
98,922,510 (GRCm39) |
missense |
unknown |
|
|
R8317:Foxp1
|
UTSW |
6 |
99,052,866 (GRCm39) |
small deletion |
probably benign |
|
|
R8408:Foxp1
|
UTSW |
6 |
98,922,543 (GRCm39) |
missense |
unknown |
|
|
R8704:Foxp1
|
UTSW |
6 |
98,993,507 (GRCm39) |
missense |
unknown |
|
|
R8705:Foxp1
|
UTSW |
6 |
98,993,507 (GRCm39) |
missense |
unknown |
|
|
R9014:Foxp1
|
UTSW |
6 |
99,052,866 (GRCm39) |
small deletion |
probably benign |
|
|
R9147:Foxp1
|
UTSW |
6 |
99,052,866 (GRCm39) |
small deletion |
probably benign |
|
|
R9399:Foxp1
|
UTSW |
6 |
99,052,866 (GRCm39) |
small deletion |
probably benign |
|
|
R9604:Foxp1
|
UTSW |
6 |
99,052,926 (GRCm39) |
small deletion |
probably benign |
|
|
X0066:Foxp1
|
UTSW |
6 |
99,052,976 (GRCm39) |
nonsense |
probably null |
|
|
Z1177:Foxp1
|
UTSW |
6 |
98,955,122 (GRCm39) |
missense |
unknown |
|
|
| Predicted Primers |
PCR Primer
(F):5'- ACACATTTTGCGCAAGTTTTCC -3'
(R):5'- GAAGGGGTTTTCCTGAGATCC -3'
Sequencing Primer
(F):5'- GATAATATCCACTTCTGCAAGGC -3'
(R):5'- TGAGATCCACTTCGTGAGGAC -3'
|
| Posted On |
2014-07-14 |
Incidental Mutation