Incidental Mutation 'R1934:Abcb5'
| ID |
215723 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Abcb5
|
| Ensembl Gene |
ENSMUSG00000072791 |
| Gene Name |
ATP-binding cassette, sub-family B member 5 |
| Synonyms |
9230106F14Rik |
| MMRRC Submission |
039952-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.131)
|
| Stock # |
R1934 (G1)
|
| Quality Score |
225 |
|
Status
|
Not validated
|
| Chromosome |
12 |
| Chromosomal Location |
118831559-118930156 bp(-) (GRCm39) |
| Type of Mutation |
splice site (6 bp from exon) |
| DNA Base Change (assembly) |
A to G
at 118871235 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000046177
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000035515]
|
| AlphaFold |
B5X0E4 |
| Predicted Effect |
probably null
Transcript: ENSMUST00000035515
|
| SMART Domains |
Protein: ENSMUSP00000046177
Gene: ENSMUSG00000072791
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:ABC_membrane
|
49 |
338 |
1.9e-74 |
PFAM |
|
AAA
|
414 |
606 |
2.1e-19 |
SMART |
|
Pfam:ABC_membrane
|
693 |
967 |
7.3e-59 |
PFAM |
|
Blast:AAA
|
969 |
1040 |
2e-11 |
BLAST |
|
AAA
|
1043 |
1231 |
8.26e-18 |
SMART |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000100982
|
| Coding Region Coverage |
- 1x: 97.5%
- 3x: 96.9%
- 10x: 95.3%
- 20x: 92.5%
|
| Validation Efficiency |
|
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] ABCB5 belongs to the ATP-binding cassette (ABC) transporter superfamily of integral membrane proteins. These proteins participate in ATP-dependent transmembrane transport of structurally diverse molecules ranging from small ions, sugars, and peptides to more complex organic molecules (Chen et al., 2005 [PubMed 15760339]).[supplied by OMIM, Mar 2008]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 100 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| A2m |
T |
C |
6: 121,626,792 (GRCm39) |
L548P |
probably damaging |
Het |
| Abca6 |
A |
G |
11: 110,100,909 (GRCm39) |
|
probably null |
Het |
| Acacb |
G |
A |
5: 114,336,343 (GRCm39) |
A686T |
probably benign |
Het |
| Acot6 |
T |
C |
12: 84,153,367 (GRCm39) |
V203A |
probably benign |
Het |
| Adam25 |
A |
T |
8: 41,207,922 (GRCm39) |
Y396F |
probably benign |
Het |
| Adamts9 |
A |
G |
6: 92,920,102 (GRCm39) |
L12P |
possibly damaging |
Het |
| Adamtsl2 |
A |
T |
2: 26,979,605 (GRCm39) |
D258V |
probably damaging |
Het |
| Aox4 |
G |
A |
1: 58,285,095 (GRCm39) |
V616I |
probably benign |
Het |
| Ap1m1 |
A |
G |
8: 73,009,637 (GRCm39) |
I382V |
probably damaging |
Het |
| Arhgef2 |
G |
A |
3: 88,537,098 (GRCm39) |
R8Q |
probably damaging |
Het |
| Arhgef37 |
T |
G |
18: 61,657,014 (GRCm39) |
E17A |
probably benign |
Het |
| Arhgef7 |
C |
A |
8: 11,858,713 (GRCm39) |
|
probably null |
Het |
| Arih1 |
T |
C |
9: 59,302,215 (GRCm39) |
D431G |
probably damaging |
Het |
| Astn2 |
C |
T |
4: 65,353,426 (GRCm39) |
V1115M |
probably damaging |
Het |
| Atg7 |
T |
A |
6: 114,678,196 (GRCm39) |
M280K |
probably damaging |
Het |
| Birc2 |
T |
C |
9: 7,854,500 (GRCm39) |
T397A |
possibly damaging |
Het |
| Ccdc110 |
A |
G |
8: 46,396,287 (GRCm39) |
N726S |
probably damaging |
Het |
| Cdadc1 |
A |
T |
14: 59,827,309 (GRCm39) |
S121T |
possibly damaging |
Het |
| Cdh16 |
A |
G |
8: 105,344,595 (GRCm39) |
V7A |
possibly damaging |
Het |
| Cenpb |
A |
G |
2: 131,021,184 (GRCm39) |
S205P |
probably benign |
Het |
| Chsy1 |
T |
C |
7: 65,821,991 (GRCm39) |
V742A |
probably damaging |
Het |
| Col12a1 |
G |
A |
9: 79,511,804 (GRCm39) |
R133* |
probably null |
Het |
| Col18a1 |
A |
C |
10: 76,948,578 (GRCm39) |
S311R |
possibly damaging |
Het |
| Col9a3 |
G |
A |
2: 180,248,927 (GRCm39) |
V260M |
probably damaging |
Het |
| Coq2 |
T |
A |
5: 100,809,731 (GRCm39) |
R17S |
probably damaging |
Het |
| Ctf1 |
A |
G |
7: 127,311,936 (GRCm39) |
R4G |
probably damaging |
Het |
| Cwc27 |
T |
C |
13: 104,768,184 (GRCm39) |
D437G |
probably benign |
Het |
| Cyp4f14 |
T |
C |
17: 33,125,289 (GRCm39) |
N430D |
probably damaging |
Het |
| Dars2 |
A |
G |
1: 160,890,811 (GRCm39) |
|
probably null |
Het |
| Dgkz |
A |
T |
2: 91,767,449 (GRCm39) |
M848K |
possibly damaging |
Het |
| Dnhd1 |
T |
G |
7: 105,357,789 (GRCm39) |
V3208G |
probably benign |
Het |
| Dsg1b |
A |
G |
18: 20,528,963 (GRCm39) |
Y233C |
probably damaging |
Het |
| Edem3 |
A |
T |
1: 151,680,034 (GRCm39) |
D460V |
probably damaging |
Het |
| Ednra |
A |
G |
8: 78,415,747 (GRCm39) |
S167P |
possibly damaging |
Het |
| Eif3m |
A |
T |
2: 104,831,624 (GRCm39) |
V180D |
probably damaging |
Het |
| Fam217a |
T |
A |
13: 35,094,864 (GRCm39) |
R207S |
probably damaging |
Het |
| Fcgbp |
G |
A |
7: 27,806,518 (GRCm39) |
G2162D |
probably damaging |
Het |
| Fhod3 |
A |
T |
18: 25,223,335 (GRCm39) |
I894F |
probably benign |
Het |
| Fpgs |
A |
T |
2: 32,577,993 (GRCm39) |
I143N |
probably damaging |
Het |
| Fpr-rs6 |
A |
G |
17: 20,403,152 (GRCm39) |
S70P |
probably benign |
Het |
| Frs2 |
T |
C |
10: 116,914,806 (GRCm39) |
M38V |
probably damaging |
Het |
| Fsip2 |
A |
G |
2: 82,810,902 (GRCm39) |
N2407S |
possibly damaging |
Het |
| Gabrg2 |
T |
A |
11: 41,811,297 (GRCm39) |
T283S |
probably benign |
Het |
| Gas2l1 |
T |
A |
11: 5,011,408 (GRCm39) |
T474S |
probably benign |
Het |
| Gli1 |
A |
T |
10: 127,167,108 (GRCm39) |
M715K |
possibly damaging |
Het |
| Glra3 |
G |
T |
8: 56,393,942 (GRCm39) |
A18S |
probably benign |
Het |
| Gm5800 |
T |
A |
14: 51,949,396 (GRCm39) |
N183I |
possibly damaging |
Het |
| Gm8674 |
T |
A |
13: 50,055,471 (GRCm39) |
|
noncoding transcript |
Het |
| Gnat3 |
A |
T |
5: 18,224,508 (GRCm39) |
I303F |
possibly damaging |
Het |
| Grin2d |
C |
T |
7: 45,506,251 (GRCm39) |
V547M |
probably damaging |
Het |
| Grpr |
C |
A |
X: 162,332,137 (GRCm39) |
V53L |
probably benign |
Het |
| Heatr5b |
T |
C |
17: 79,103,347 (GRCm39) |
I1169V |
possibly damaging |
Het |
| Icam5 |
A |
G |
9: 20,946,082 (GRCm39) |
T305A |
probably benign |
Het |
| Itga11 |
T |
A |
9: 62,651,796 (GRCm39) |
N309K |
probably damaging |
Het |
| Itgb6 |
T |
C |
2: 60,499,493 (GRCm39) |
D100G |
probably benign |
Het |
| Kdm3b |
A |
G |
18: 34,946,597 (GRCm39) |
K862R |
probably benign |
Het |
| Kif7 |
T |
C |
7: 79,361,286 (GRCm39) |
D135G |
probably benign |
Het |
| Lrp4 |
A |
G |
2: 91,310,777 (GRCm39) |
D606G |
probably damaging |
Het |
| Lrrtm1 |
A |
T |
6: 77,221,949 (GRCm39) |
|
probably null |
Het |
| Metap1d |
A |
T |
2: 71,352,927 (GRCm39) |
H252L |
possibly damaging |
Het |
| Mfhas1 |
A |
G |
8: 36,058,251 (GRCm39) |
K909E |
possibly damaging |
Het |
| Mrgprh |
C |
T |
17: 13,095,838 (GRCm39) |
T26I |
probably damaging |
Het |
| Myo15b |
T |
C |
11: 115,754,310 (GRCm39) |
S937P |
probably benign |
Het |
| Neto2 |
A |
T |
8: 86,397,033 (GRCm39) |
I73N |
possibly damaging |
Het |
| Nod2 |
T |
C |
8: 89,390,347 (GRCm39) |
I196T |
probably benign |
Het |
| Nvl |
T |
G |
1: 180,926,693 (GRCm39) |
T788P |
probably damaging |
Het |
| Or13a25 |
C |
A |
7: 140,247,951 (GRCm39) |
C243* |
probably null |
Het |
| Or2h2 |
A |
T |
17: 37,396,906 (GRCm39) |
D50E |
possibly damaging |
Het |
| Pax3 |
G |
A |
1: 78,080,117 (GRCm39) |
T423I |
possibly damaging |
Het |
| Pde4dip |
A |
G |
3: 97,600,007 (GRCm39) |
V2403A |
possibly damaging |
Het |
| Phip |
C |
T |
9: 82,785,235 (GRCm39) |
V827I |
probably benign |
Het |
| Plcb3 |
A |
G |
19: 6,941,977 (GRCm39) |
F285L |
probably damaging |
Het |
| Pnp2 |
A |
G |
14: 51,193,675 (GRCm39) |
I16V |
probably benign |
Het |
| Pola2 |
A |
G |
19: 6,003,769 (GRCm39) |
L202P |
probably damaging |
Het |
| Ppfia1 |
A |
T |
7: 144,058,847 (GRCm39) |
N651K |
probably benign |
Het |
| Prss53 |
T |
C |
7: 127,485,920 (GRCm39) |
|
probably null |
Het |
| Rasgrf1 |
G |
T |
9: 89,835,966 (GRCm39) |
Q231H |
probably damaging |
Het |
| Rasgrf2 |
A |
T |
13: 92,131,825 (GRCm39) |
|
probably null |
Het |
| Rccd1 |
T |
A |
7: 79,970,272 (GRCm39) |
N115I |
possibly damaging |
Het |
| Rpgrip1 |
A |
T |
14: 52,352,101 (GRCm39) |
T26S |
possibly damaging |
Het |
| Rpn1 |
T |
A |
6: 88,070,841 (GRCm39) |
V237E |
probably damaging |
Het |
| Sema4f |
G |
T |
6: 82,907,908 (GRCm39) |
P180Q |
probably damaging |
Het |
| Slc36a4 |
T |
C |
9: 15,632,085 (GRCm39) |
V87A |
probably damaging |
Het |
| Slc5a4b |
A |
T |
10: 75,917,307 (GRCm39) |
V243E |
possibly damaging |
Het |
| Sos2 |
T |
G |
12: 69,695,315 (GRCm39) |
I141L |
probably damaging |
Het |
| Srbd1 |
A |
G |
17: 86,410,321 (GRCm39) |
V537A |
probably damaging |
Het |
| Sugp1 |
A |
G |
8: 70,509,225 (GRCm39) |
E166G |
possibly damaging |
Het |
| Tktl2 |
G |
A |
8: 66,964,999 (GRCm39) |
V186M |
probably damaging |
Het |
| Tshr |
T |
C |
12: 91,503,955 (GRCm39) |
S298P |
probably damaging |
Het |
| Tspan14 |
T |
C |
14: 40,656,209 (GRCm39) |
Y6C |
probably damaging |
Het |
| Ttn |
A |
T |
2: 76,577,384 (GRCm39) |
V24503E |
probably damaging |
Het |
| Vcan |
T |
A |
13: 89,851,045 (GRCm39) |
N1305I |
probably damaging |
Het |
| Vmn2r81 |
A |
G |
10: 79,083,628 (GRCm39) |
M1V |
probably null |
Het |
| Vps39 |
A |
T |
2: 120,148,558 (GRCm39) |
V873E |
probably damaging |
Het |
| Vstm2a |
A |
T |
11: 16,359,734 (GRCm39) |
D270V |
unknown |
Het |
| Wdr24 |
A |
T |
17: 26,043,240 (GRCm39) |
M21L |
possibly damaging |
Het |
| Wee1 |
A |
G |
7: 109,721,698 (GRCm39) |
T48A |
probably benign |
Het |
| Zfp369 |
T |
C |
13: 65,444,965 (GRCm39) |
C703R |
probably damaging |
Het |
| Zfp532 |
A |
T |
18: 65,818,682 (GRCm39) |
D1114V |
probably damaging |
Het |
| Zfp758 |
A |
G |
17: 22,592,633 (GRCm39) |
T46A |
probably damaging |
Het |
|
| Other mutations in Abcb5 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00090:Abcb5
|
APN |
12 |
118,854,345 (GRCm39) |
missense |
probably benign |
0.03 |
|
IGL00092:Abcb5
|
APN |
12 |
118,892,430 (GRCm39) |
missense |
probably benign |
0.09 |
|
IGL00503:Abcb5
|
APN |
12 |
118,871,336 (GRCm39) |
missense |
probably benign |
0.02 |
|
IGL00776:Abcb5
|
APN |
12 |
118,883,589 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01116:Abcb5
|
APN |
12 |
118,849,911 (GRCm39) |
missense |
probably benign |
|
|
IGL01302:Abcb5
|
APN |
12 |
118,881,935 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01403:Abcb5
|
APN |
12 |
118,836,602 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01453:Abcb5
|
APN |
12 |
118,831,705 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01541:Abcb5
|
APN |
12 |
118,875,169 (GRCm39) |
missense |
probably benign |
0.03 |
|
IGL01784:Abcb5
|
APN |
12 |
118,854,399 (GRCm39) |
missense |
probably benign |
0.14 |
|
IGL01967:Abcb5
|
APN |
12 |
118,831,707 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01987:Abcb5
|
APN |
12 |
118,891,093 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02104:Abcb5
|
APN |
12 |
118,904,415 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02161:Abcb5
|
APN |
12 |
118,838,490 (GRCm39) |
missense |
probably benign |
|
|
IGL02292:Abcb5
|
APN |
12 |
118,881,932 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02381:Abcb5
|
APN |
12 |
118,904,413 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02544:Abcb5
|
APN |
12 |
118,870,003 (GRCm39) |
splice site |
probably benign |
|
|
IGL02685:Abcb5
|
APN |
12 |
118,869,682 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL02824:Abcb5
|
APN |
12 |
118,854,420 (GRCm39) |
missense |
probably benign |
0.05 |
|
IGL02876:Abcb5
|
APN |
12 |
118,883,576 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02929:Abcb5
|
APN |
12 |
118,908,674 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL03030:Abcb5
|
APN |
12 |
118,904,104 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
IGL03062:Abcb5
|
APN |
12 |
118,899,822 (GRCm39) |
missense |
probably benign |
0.43 |
|
IGL03200:Abcb5
|
APN |
12 |
118,928,989 (GRCm39) |
splice site |
probably benign |
|
|
IGL03407:Abcb5
|
APN |
12 |
118,904,111 (GRCm39) |
missense |
probably benign |
0.01 |
|
alphabet
|
UTSW |
12 |
118,854,353 (GRCm39) |
missense |
possibly damaging |
0.67 |
|
google
|
UTSW |
12 |
118,831,665 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
F5770:Abcb5
|
UTSW |
12 |
118,849,914 (GRCm39) |
missense |
probably benign |
0.07 |
|
PIT4366001:Abcb5
|
UTSW |
12 |
118,899,833 (GRCm39) |
missense |
probably damaging |
1.00 |
|
PIT4434001:Abcb5
|
UTSW |
12 |
118,854,422 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0078:Abcb5
|
UTSW |
12 |
118,891,129 (GRCm39) |
missense |
probably benign |
|
|
R0219:Abcb5
|
UTSW |
12 |
118,849,885 (GRCm39) |
splice site |
probably benign |
|
|
R0312:Abcb5
|
UTSW |
12 |
118,836,572 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0347:Abcb5
|
UTSW |
12 |
118,928,986 (GRCm39) |
splice site |
probably benign |
|
|
R0359:Abcb5
|
UTSW |
12 |
118,904,067 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0433:Abcb5
|
UTSW |
12 |
118,841,545 (GRCm39) |
missense |
probably benign |
0.03 |
|
R0582:Abcb5
|
UTSW |
12 |
118,904,147 (GRCm39) |
missense |
probably benign |
0.40 |
|
R0815:Abcb5
|
UTSW |
12 |
118,865,184 (GRCm39) |
splice site |
probably benign |
|
|
R0900:Abcb5
|
UTSW |
12 |
118,904,359 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0942:Abcb5
|
UTSW |
12 |
118,869,933 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R0988:Abcb5
|
UTSW |
12 |
118,896,310 (GRCm39) |
missense |
probably benign |
0.36 |
|
R1125:Abcb5
|
UTSW |
12 |
118,875,282 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
R1437:Abcb5
|
UTSW |
12 |
118,838,497 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1469:Abcb5
|
UTSW |
12 |
118,831,681 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R1469:Abcb5
|
UTSW |
12 |
118,831,681 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R1678:Abcb5
|
UTSW |
12 |
118,929,064 (GRCm39) |
start gained |
probably benign |
|
|
R1726:Abcb5
|
UTSW |
12 |
118,871,267 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R1726:Abcb5
|
UTSW |
12 |
118,838,536 (GRCm39) |
splice site |
probably null |
|
|
R1836:Abcb5
|
UTSW |
12 |
118,831,696 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R1976:Abcb5
|
UTSW |
12 |
118,854,417 (GRCm39) |
missense |
probably benign |
|
|
R2005:Abcb5
|
UTSW |
12 |
118,841,562 (GRCm39) |
missense |
probably benign |
0.15 |
|
R2068:Abcb5
|
UTSW |
12 |
118,904,303 (GRCm39) |
nonsense |
probably null |
|
|
R2181:Abcb5
|
UTSW |
12 |
118,831,681 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R2191:Abcb5
|
UTSW |
12 |
118,831,691 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3690:Abcb5
|
UTSW |
12 |
118,836,668 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3746:Abcb5
|
UTSW |
12 |
118,838,355 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R3825:Abcb5
|
UTSW |
12 |
118,865,087 (GRCm39) |
splice site |
probably null |
|
|
R3919:Abcb5
|
UTSW |
12 |
118,854,353 (GRCm39) |
missense |
possibly damaging |
0.67 |
|
R4049:Abcb5
|
UTSW |
12 |
118,832,404 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4409:Abcb5
|
UTSW |
12 |
118,836,657 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R4606:Abcb5
|
UTSW |
12 |
118,896,345 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R4705:Abcb5
|
UTSW |
12 |
118,929,040 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R4954:Abcb5
|
UTSW |
12 |
118,875,169 (GRCm39) |
missense |
probably benign |
0.03 |
|
R4966:Abcb5
|
UTSW |
12 |
118,850,626 (GRCm39) |
intron |
probably benign |
|
|
R5169:Abcb5
|
UTSW |
12 |
118,841,552 (GRCm39) |
nonsense |
probably null |
|
|
R5327:Abcb5
|
UTSW |
12 |
118,875,278 (GRCm39) |
missense |
probably benign |
0.01 |
|
R5333:Abcb5
|
UTSW |
12 |
118,831,677 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5366:Abcb5
|
UTSW |
12 |
118,831,665 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R5373:Abcb5
|
UTSW |
12 |
118,850,912 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5399:Abcb5
|
UTSW |
12 |
118,875,234 (GRCm39) |
missense |
probably benign |
|
|
R5416:Abcb5
|
UTSW |
12 |
118,871,331 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5447:Abcb5
|
UTSW |
12 |
118,891,061 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5474:Abcb5
|
UTSW |
12 |
118,904,425 (GRCm39) |
missense |
probably null |
1.00 |
|
R5566:Abcb5
|
UTSW |
12 |
118,899,702 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5685:Abcb5
|
UTSW |
12 |
118,896,348 (GRCm39) |
splice site |
probably null |
|
|
R5691:Abcb5
|
UTSW |
12 |
118,890,970 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5742:Abcb5
|
UTSW |
12 |
118,881,992 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R5852:Abcb5
|
UTSW |
12 |
118,891,139 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5917:Abcb5
|
UTSW |
12 |
118,832,516 (GRCm39) |
nonsense |
probably null |
|
|
R5994:Abcb5
|
UTSW |
12 |
118,928,995 (GRCm39) |
critical splice donor site |
probably null |
|
|
R6295:Abcb5
|
UTSW |
12 |
118,838,379 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6455:Abcb5
|
UTSW |
12 |
118,854,284 (GRCm39) |
critical splice donor site |
probably null |
|
|
R6609:Abcb5
|
UTSW |
12 |
118,892,497 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6753:Abcb5
|
UTSW |
12 |
118,908,641 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
R6818:Abcb5
|
UTSW |
12 |
118,865,089 (GRCm39) |
splice site |
probably null |
|
|
R6870:Abcb5
|
UTSW |
12 |
118,929,000 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
R6944:Abcb5
|
UTSW |
12 |
118,875,265 (GRCm39) |
missense |
probably benign |
0.06 |
|
R6957:Abcb5
|
UTSW |
12 |
118,871,270 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6984:Abcb5
|
UTSW |
12 |
118,891,012 (GRCm39) |
missense |
possibly damaging |
0.47 |
|
R7021:Abcb5
|
UTSW |
12 |
118,895,660 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7061:Abcb5
|
UTSW |
12 |
118,841,509 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7175:Abcb5
|
UTSW |
12 |
118,831,611 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7239:Abcb5
|
UTSW |
12 |
118,892,460 (GRCm39) |
missense |
probably benign |
0.19 |
|
R7267:Abcb5
|
UTSW |
12 |
118,916,205 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7303:Abcb5
|
UTSW |
12 |
118,875,295 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R7396:Abcb5
|
UTSW |
12 |
118,831,609 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7605:Abcb5
|
UTSW |
12 |
118,881,899 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7989:Abcb5
|
UTSW |
12 |
118,875,278 (GRCm39) |
missense |
probably benign |
0.01 |
|
R8177:Abcb5
|
UTSW |
12 |
118,836,525 (GRCm39) |
missense |
possibly damaging |
0.65 |
|
R8296:Abcb5
|
UTSW |
12 |
118,838,467 (GRCm39) |
missense |
probably benign |
0.01 |
|
R8544:Abcb5
|
UTSW |
12 |
118,832,461 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8558:Abcb5
|
UTSW |
12 |
118,841,566 (GRCm39) |
missense |
probably benign |
0.07 |
|
R8790:Abcb5
|
UTSW |
12 |
118,831,620 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R9003:Abcb5
|
UTSW |
12 |
118,850,013 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R9038:Abcb5
|
UTSW |
12 |
118,895,651 (GRCm39) |
missense |
probably benign |
|
|
R9410:Abcb5
|
UTSW |
12 |
118,869,703 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9497:Abcb5
|
UTSW |
12 |
118,899,850 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R9666:Abcb5
|
UTSW |
12 |
118,838,422 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R9682:Abcb5
|
UTSW |
12 |
118,896,328 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9756:Abcb5
|
UTSW |
12 |
118,881,873 (GRCm39) |
missense |
probably damaging |
0.98 |
|
V7580:Abcb5
|
UTSW |
12 |
118,849,914 (GRCm39) |
missense |
probably benign |
0.07 |
|
Z1176:Abcb5
|
UTSW |
12 |
118,882,007 (GRCm39) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- TAACAGACATGGTCCATCTCCTG -3'
(R):5'- ATAGGTTCCAGTGCACTTCCG -3'
Sequencing Primer
(F):5'- GTCCATCTCCTGGGCTCAG -3'
(R):5'- CCATAATACCCTCAGACTGATGTTG -3'
|
| Posted On |
2014-07-14 |
Incidental Mutation