Mutagenetix > Incidental Mutation

Incidental Mutation 'R0057:Zfa-ps'

216074

Institutional Source

Beutler Lab

Gene Symbol

Zfa-ps

Ensembl Gene

ENSMUSG00000049576

Gene Name

zinc finger protein, autosomal, pseudogene

Synonyms

Zfa

MMRRC Submission

038351-MU

Accession Numbers

Essential gene?

Probably non essential (E-score: 0.218) question?

Stock #

R0057 (G1)

Quality Score

Status

Validated

Chromosome

Chromosomal Location

52418416-52421835 bp(-) (GRCm39)

Type of Mutation

exon

DNA Base Change (assembly)

A to T at 52421202 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Gene Model

predicted gene model for transcript(s):

AlphaFold

no structure available at present

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000180526

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000180673

Meta Mutation Damage Score

0.0844

Coding Region Coverage

1x: 99.3%
3x: 98.9%
10x: 97.7%
20x: 95.9%

Validation Efficiency

100% (50/50)

Allele List at MGI

Other mutations in this stock

Total: 28 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Adam23	T	A	1: 63,610,078 (GRCm39)	H693Q	probably damaging	Het
Ap5z1	T	C	5: 142,456,144 (GRCm39)		probably benign	Het
Bloc1s6	T	A	2: 122,586,141 (GRCm39)		probably benign	Het
Caskin1	A	G	17: 24,723,870 (GRCm39)	N886S	probably damaging	Het
Ctse	G	T	1: 131,591,109 (GRCm39)	D97Y	probably damaging	Het
Dcaf11	T	C	14: 55,806,767 (GRCm39)	V490A	probably benign	Het
Dctn1	A	G	6: 83,156,874 (GRCm39)	H7R	probably benign	Het
Dscam	A	C	16: 96,474,936 (GRCm39)	W1209G	probably damaging	Het
Fcsk	C	T	8: 111,620,400 (GRCm39)		probably benign	Het
Gna11	A	G	10: 81,366,774 (GRCm39)	M312T	probably benign	Het
Hacd2	T	A	16: 34,895,997 (GRCm39)	V105D	probably damaging	Het
Htra4	C	A	8: 25,528,824 (GRCm39)	V23L	probably benign	Het
Marf1	C	T	16: 13,960,398 (GRCm39)	A549T	probably damaging	Het
Msh4	C	T	3: 153,575,318 (GRCm39)	A686T	probably benign	Het
Nbas	T	A	12: 13,440,958 (GRCm39)	M1096K	probably benign	Het
Or5m10b	C	A	2: 85,699,597 (GRCm39)	Y220*	probably null	Het
Ppp1r16a	C	T	15: 76,574,999 (GRCm39)		probably benign	Het
Prlr	A	G	15: 10,328,509 (GRCm39)	Y328C	probably damaging	Het
Ros1	C	T	10: 52,056,287 (GRCm39)	V68I	probably benign	Het
Shmt2	G	A	10: 127,356,917 (GRCm39)	T31M	possibly damaging	Het
Snapc1	C	T	12: 74,021,806 (GRCm39)	R81C	probably damaging	Het
Tas2r135	A	G	6: 42,383,354 (GRCm39)	T298A	probably benign	Het
Tmem175	C	T	5: 108,787,428 (GRCm39)	H92Y	probably damaging	Het
Top3a	C	T	11: 60,631,510 (GRCm39)	A951T	probably benign	Het
Trpc4ap	T	C	2: 155,482,406 (GRCm39)	E528G	possibly damaging	Het
Trpm6	T	C	19: 18,764,119 (GRCm39)	C242R	probably benign	Het
Vwa7	G	A	17: 35,243,523 (GRCm39)	S710N	possibly damaging	Het
Zfp770	T	A	2: 114,027,713 (GRCm39)	R119*	probably null	Het

Other mutations in Zfa-ps

Allele	Source	Chr	Coord	Type	Predicted Effect
IGL00960:Zfa-ps	APN	10	52,420,043 (GRCm39)	exon	noncoding transcript
R0057:Zfa-ps	UTSW	10	52,421,202 (GRCm39)	exon	noncoding transcript
R1159:Zfa-ps	UTSW	10	52,419,654 (GRCm39)	exon	noncoding transcript
R2145:Zfa-ps	UTSW	10	52,419,373 (GRCm39)	exon	noncoding transcript
R2290:Zfa-ps	UTSW	10	52,421,112 (GRCm39)	exon	noncoding transcript
R2509:Zfa-ps	UTSW	10	52,420,339 (GRCm39)	exon	noncoding transcript
R3738:Zfa-ps	UTSW	10	52,420,636 (GRCm39)	exon	noncoding transcript
R4035:Zfa-ps	UTSW	10	52,420,636 (GRCm39)	exon	noncoding transcript
R4290:Zfa-ps	UTSW	10	52,419,807 (GRCm39)	exon	noncoding transcript
R4545:Zfa-ps	UTSW	10	52,421,032 (GRCm39)	exon	noncoding transcript
R4862:Zfa-ps	UTSW	10	52,419,192 (GRCm39)	exon	noncoding transcript
R5135:Zfa-ps	UTSW	10	52,419,118 (GRCm39)	exon	noncoding transcript
R5270:Zfa-ps	UTSW	10	52,419,552 (GRCm39)	exon	noncoding transcript

Predicted Primers

PCR Primer
(F):5'- CATGAACCACATGTTCAACGTGACC -3'
(R):5'- TGAAACAGGTGTTCTGGCTGATGAG -3'

Sequencing Primer
(F):5'- CAAGACTCGTTTCGGCATAG -3'
(R):5'- TCTGGCTGATGAGAATTTAAAGGC -3'

Posted On

2014-07-21