Incidental Mutation 'R0671:Mroh2a'
| ID |
216137 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Mroh2a
|
| Ensembl Gene |
ENSMUSG00000079429 |
| Gene Name |
maestro heat-like repeat family member 2A |
| Synonyms |
ENSMUSG00000044873, Heatr7b1, OTTMUSG00000020804 |
| MMRRC Submission |
038856-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably essential
(E-score: 0.937)
|
| Stock # |
R0671 (G1)
|
| Quality Score |
33 |
|
Status
|
Validated
|
| Chromosome |
1 |
| Chromosomal Location |
88154713-88190011 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
C to A
at 88170142 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Alanine to Aspartic acid
at position 685
(A685D)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000108755
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000061013]
[ENSMUST00000113130]
|
| AlphaFold |
D3Z750 |
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000061013
AA Change: A688D
PolyPhen 2
Score 0.721 (Sensitivity: 0.86; Specificity: 0.92)
|
| SMART Domains |
Protein: ENSMUSP00000130508
Gene: ENSMUSG00000079429
AA Change: A688D
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
9 |
26 |
N/A |
INTRINSIC |
|
low complexity region
|
99 |
112 |
N/A |
INTRINSIC |
|
low complexity region
|
1235 |
1248 |
N/A |
INTRINSIC |
|
SCOP:d1jdha_
|
1371 |
1669 |
9e-8 |
SMART |
|
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000113130
AA Change: A685D
PolyPhen 2
Score 0.769 (Sensitivity: 0.85; Specificity: 0.92)
|
| SMART Domains |
Protein: ENSMUSP00000108755
Gene: ENSMUSG00000079429
AA Change: A685D
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
9 |
26 |
N/A |
INTRINSIC |
|
low complexity region
|
99 |
112 |
N/A |
INTRINSIC |
|
low complexity region
|
1232 |
1245 |
N/A |
INTRINSIC |
|
SCOP:d1gw5a_
|
1446 |
1671 |
6e-6 |
SMART |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000142632
|
| Meta Mutation Damage Score |
0.2131 |
| Coding Region Coverage |
- 1x: 99.4%
- 3x: 98.9%
- 10x: 97.7%
- 20x: 96.1%
|
| Validation Efficiency |
99% (125/126) |
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a HEAT-domain-containing protein. The function of the encoded protein has not been characterized. [provided by RefSeq, Aug 2016]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 115 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 1700067K01Rik |
T |
C |
8: 84,729,637 (GRCm39) |
|
probably benign |
Het |
| A530064D06Rik |
G |
A |
17: 48,473,824 (GRCm39) |
T31I |
probably benign |
Het |
| Abca17 |
A |
G |
17: 24,500,223 (GRCm39) |
F1323L |
probably benign |
Het |
| Abcf3 |
T |
A |
16: 20,369,237 (GRCm39) |
N206K |
probably damaging |
Het |
| Adam10 |
A |
G |
9: 70,673,223 (GRCm39) |
|
probably benign |
Het |
| Adamtsl3 |
A |
T |
7: 82,172,390 (GRCm39) |
Q451L |
probably damaging |
Het |
| Adgrl3 |
T |
A |
5: 81,708,752 (GRCm39) |
I413N |
probably benign |
Het |
| Asb18 |
G |
T |
1: 89,920,893 (GRCm39) |
A128E |
probably damaging |
Het |
| Atf7ip2 |
T |
C |
16: 10,059,743 (GRCm39) |
S428P |
possibly damaging |
Het |
| Atp8b5 |
G |
T |
4: 43,291,672 (GRCm39) |
C15F |
possibly damaging |
Het |
| Bahcc1 |
A |
G |
11: 120,178,146 (GRCm39) |
E2235G |
probably damaging |
Het |
| Blnk |
G |
T |
19: 40,926,111 (GRCm39) |
S330* |
probably null |
Het |
| Bpnt1 |
T |
G |
1: 185,088,808 (GRCm39) |
N319K |
probably benign |
Het |
| Brip1 |
G |
A |
11: 86,043,493 (GRCm39) |
T357I |
possibly damaging |
Het |
| Cadm1 |
T |
A |
9: 47,725,104 (GRCm39) |
D288E |
probably benign |
Het |
| Calcoco2 |
A |
G |
11: 95,998,354 (GRCm39) |
V23A |
probably damaging |
Het |
| Cand2 |
G |
A |
6: 115,780,766 (GRCm39) |
E1217K |
probably damaging |
Het |
| Ccdc154 |
G |
T |
17: 25,386,259 (GRCm39) |
|
probably benign |
Het |
| Cdk12 |
T |
C |
11: 98,120,935 (GRCm39) |
|
probably benign |
Het |
| Clec4a3 |
A |
G |
6: 122,930,993 (GRCm39) |
|
probably null |
Het |
| Cpne2 |
T |
A |
8: 95,274,970 (GRCm39) |
|
probably benign |
Het |
| Cyfip1 |
T |
C |
7: 55,573,710 (GRCm39) |
|
probably null |
Het |
| Cyp26c1 |
A |
G |
19: 37,675,009 (GRCm39) |
H110R |
probably damaging |
Het |
| Cyp2j13 |
A |
G |
4: 95,959,932 (GRCm39) |
Y75H |
probably damaging |
Het |
| Defb43 |
T |
A |
14: 63,249,287 (GRCm39) |
V10D |
probably damaging |
Het |
| Dhx36 |
G |
A |
3: 62,401,162 (GRCm39) |
S368L |
possibly damaging |
Het |
| Dock6 |
G |
A |
9: 21,715,923 (GRCm39) |
|
probably benign |
Het |
| Elp2 |
T |
C |
18: 24,745,499 (GRCm39) |
|
probably benign |
Het |
| Emilin3 |
A |
G |
2: 160,750,249 (GRCm39) |
L453P |
probably damaging |
Het |
| Eml6 |
A |
T |
11: 29,755,065 (GRCm39) |
D903E |
probably benign |
Het |
| Ep300 |
T |
C |
15: 81,500,335 (GRCm39) |
|
probably benign |
Het |
| Ep400 |
G |
A |
5: 110,836,062 (GRCm39) |
T1899M |
unknown |
Het |
| Fancg |
A |
G |
4: 43,002,998 (GRCm39) |
S620P |
probably benign |
Het |
| Fbxo42 |
G |
A |
4: 140,922,550 (GRCm39) |
V239M |
probably damaging |
Het |
| Fermt2 |
T |
C |
14: 45,706,776 (GRCm39) |
D340G |
probably benign |
Het |
| Filip1 |
A |
T |
9: 79,726,672 (GRCm39) |
V649E |
probably damaging |
Het |
| Fut8 |
G |
A |
12: 77,521,791 (GRCm39) |
E477K |
probably damaging |
Het |
| Gbp3 |
G |
A |
3: 142,271,151 (GRCm39) |
G185D |
probably benign |
Het |
| Gclc |
G |
T |
9: 77,694,080 (GRCm39) |
D345Y |
probably damaging |
Het |
| Gfus |
A |
G |
15: 75,800,807 (GRCm39) |
V27A |
possibly damaging |
Het |
| Gkn2 |
A |
G |
6: 87,352,800 (GRCm39) |
D43G |
possibly damaging |
Het |
| Gnptab |
A |
G |
10: 88,279,166 (GRCm39) |
|
probably benign |
Het |
| Greb1l |
C |
T |
18: 10,474,303 (GRCm39) |
T206I |
probably damaging |
Het |
| Grk4 |
A |
G |
5: 34,905,611 (GRCm39) |
N452S |
probably benign |
Het |
| Hcn2 |
G |
C |
10: 79,570,066 (GRCm39) |
|
probably null |
Het |
| Hpn |
T |
C |
7: 30,808,585 (GRCm39) |
K76E |
possibly damaging |
Het |
| Hspg2 |
A |
G |
4: 137,280,591 (GRCm39) |
D3268G |
probably damaging |
Het |
| Immt |
A |
T |
6: 71,848,541 (GRCm39) |
Q467L |
possibly damaging |
Het |
| Kalrn |
T |
C |
16: 33,936,778 (GRCm39) |
S1636G |
probably benign |
Het |
| Kcnh8 |
T |
A |
17: 53,285,141 (GRCm39) |
L1037* |
probably null |
Het |
| Klhl33 |
T |
C |
14: 51,129,851 (GRCm39) |
T548A |
probably damaging |
Het |
| Klri2 |
T |
C |
6: 129,717,171 (GRCm39) |
I71V |
probably benign |
Het |
| Kmt2c |
A |
T |
5: 25,609,363 (GRCm39) |
C254S |
probably damaging |
Het |
| Lama3 |
T |
C |
18: 12,610,647 (GRCm39) |
I1170T |
possibly damaging |
Het |
| Med12l |
A |
G |
3: 59,172,350 (GRCm39) |
Q1702R |
probably damaging |
Het |
| Mga |
A |
T |
2: 119,750,391 (GRCm39) |
|
probably null |
Het |
| Mis18a |
A |
T |
16: 90,517,561 (GRCm39) |
I172K |
possibly damaging |
Het |
| Mrgpre |
T |
C |
7: 143,335,254 (GRCm39) |
D83G |
probably benign |
Het |
| Mrpl39 |
T |
C |
16: 84,531,282 (GRCm39) |
|
probably benign |
Het |
| Mrrf |
C |
T |
2: 36,043,710 (GRCm39) |
A149V |
probably benign |
Het |
| Mycbp2 |
A |
T |
14: 103,432,024 (GRCm39) |
M2338K |
possibly damaging |
Het |
| Myo18b |
T |
C |
5: 112,840,632 (GRCm39) |
Q2387R |
probably benign |
Het |
| N4bp2 |
T |
C |
5: 65,964,780 (GRCm39) |
I943T |
probably damaging |
Het |
| Ncapd3 |
T |
A |
9: 26,998,773 (GRCm39) |
N1254K |
probably benign |
Het |
| Ncoa1 |
A |
T |
12: 4,299,758 (GRCm39) |
|
probably null |
Het |
| Ncor2 |
C |
T |
5: 125,126,451 (GRCm39) |
A136T |
probably benign |
Het |
| Opa1 |
T |
C |
16: 29,421,025 (GRCm39) |
|
probably benign |
Het |
| Or13a25 |
A |
G |
7: 140,247,590 (GRCm39) |
D123G |
probably damaging |
Het |
| Or5p59 |
C |
A |
7: 107,703,363 (GRCm39) |
Y282* |
probably null |
Het |
| Or8b39 |
T |
A |
9: 37,996,423 (GRCm39) |
M97K |
possibly damaging |
Het |
| Or9e1 |
T |
A |
11: 58,732,681 (GRCm39) |
I247N |
possibly damaging |
Het |
| Pcdhb4 |
T |
C |
18: 37,440,795 (GRCm39) |
M35T |
probably benign |
Het |
| Per3 |
T |
C |
4: 151,113,288 (GRCm39) |
I347V |
probably benign |
Het |
| Pex13 |
G |
A |
11: 23,615,831 (GRCm39) |
P5L |
possibly damaging |
Het |
| Phkb |
T |
A |
8: 86,602,322 (GRCm39) |
W38R |
probably damaging |
Het |
| Plekhf1 |
A |
T |
7: 37,920,826 (GRCm39) |
D247E |
probably benign |
Het |
| Plxnb2 |
A |
G |
15: 89,042,184 (GRCm39) |
S1607P |
probably benign |
Het |
| Plxnc1 |
T |
A |
10: 94,635,194 (GRCm39) |
H1344L |
possibly damaging |
Het |
| Potefam1 |
A |
C |
2: 111,034,482 (GRCm39) |
V350G |
possibly damaging |
Het |
| Ptk7 |
T |
G |
17: 46,901,238 (GRCm39) |
N196H |
possibly damaging |
Het |
| Rab27a |
G |
T |
9: 72,982,715 (GRCm39) |
D7Y |
probably damaging |
Het |
| Rars2 |
T |
A |
4: 34,630,505 (GRCm39) |
C82* |
probably null |
Het |
| Rccd1 |
A |
T |
7: 79,969,965 (GRCm39) |
|
probably benign |
Het |
| Riiad1 |
T |
C |
3: 94,379,546 (GRCm39) |
I56V |
possibly damaging |
Het |
| Rnase4 |
A |
G |
14: 51,342,507 (GRCm39) |
E77G |
probably damaging |
Het |
| Rnf126 |
A |
T |
10: 79,597,441 (GRCm39) |
I157N |
possibly damaging |
Het |
| Rnf207 |
T |
C |
4: 152,391,925 (GRCm39) |
R623G |
probably benign |
Het |
| Rpusd1 |
T |
G |
17: 25,947,498 (GRCm39) |
F62V |
possibly damaging |
Het |
| Rxfp1 |
T |
C |
3: 79,570,600 (GRCm39) |
|
probably null |
Het |
| Scfd1 |
A |
T |
12: 51,459,411 (GRCm39) |
Q324L |
probably benign |
Het |
| Skint3 |
G |
T |
4: 112,112,974 (GRCm39) |
E195* |
probably null |
Het |
| Slc7a10 |
A |
T |
7: 34,896,758 (GRCm39) |
T165S |
probably benign |
Het |
| Smagp |
A |
G |
15: 100,519,733 (GRCm39) |
I97T |
probably damaging |
Het |
| Sostdc1 |
A |
G |
12: 36,367,340 (GRCm39) |
H172R |
probably damaging |
Het |
| Spast |
A |
G |
17: 74,646,446 (GRCm39) |
|
probably benign |
Het |
| Sspo |
G |
T |
6: 48,467,325 (GRCm39) |
|
probably benign |
Het |
| Ston2 |
C |
T |
12: 91,707,240 (GRCm39) |
|
probably null |
Het |
| Tas2r103 |
T |
G |
6: 133,013,313 (GRCm39) |
E251A |
probably benign |
Het |
| Tbc1d2b |
A |
T |
9: 90,104,558 (GRCm39) |
|
probably benign |
Het |
| Telo2 |
G |
A |
17: 25,332,139 (GRCm39) |
P143L |
probably benign |
Het |
| Tgfbi |
A |
T |
13: 56,786,539 (GRCm39) |
Y674F |
probably null |
Het |
| Tha1 |
T |
A |
11: 117,763,983 (GRCm39) |
|
probably benign |
Het |
| Timp4 |
T |
A |
6: 115,226,814 (GRCm39) |
S110C |
probably damaging |
Het |
| Tlr6 |
T |
C |
5: 65,111,935 (GRCm39) |
K324R |
probably benign |
Het |
| Tnip3 |
A |
G |
6: 65,574,347 (GRCm39) |
E137G |
probably damaging |
Het |
| Top6bl |
A |
G |
19: 4,676,216 (GRCm39) |
S639P |
probably damaging |
Het |
| Trak1 |
T |
C |
9: 121,278,021 (GRCm39) |
|
probably null |
Het |
| Trim47 |
A |
G |
11: 115,999,178 (GRCm39) |
S233P |
probably benign |
Het |
| Tspoap1 |
A |
T |
11: 87,653,635 (GRCm39) |
E155V |
probably damaging |
Het |
| Uggt1 |
A |
T |
1: 36,194,209 (GRCm39) |
L1343Q |
probably damaging |
Het |
| Utp14b |
T |
C |
1: 78,642,452 (GRCm39) |
S117P |
probably benign |
Het |
| Vmn1r124 |
A |
T |
7: 20,994,436 (GRCm39) |
V36D |
probably damaging |
Het |
| Wdr27 |
T |
C |
17: 15,148,658 (GRCm39) |
T112A |
probably benign |
Het |
| Wdr90 |
T |
C |
17: 26,065,367 (GRCm39) |
T1630A |
probably benign |
Het |
| Zfp352 |
A |
G |
4: 90,112,156 (GRCm39) |
T99A |
probably benign |
Het |
|
| Other mutations in Mroh2a |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00990:Mroh2a
|
APN |
1 |
88,172,692 (GRCm39) |
missense |
probably benign |
0.03 |
|
IGL00990:Mroh2a
|
APN |
1 |
88,161,842 (GRCm39) |
missense |
possibly damaging |
0.76 |
|
IGL00990:Mroh2a
|
APN |
1 |
88,158,468 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL03097:Mroh2a
|
UTSW |
1 |
88,163,098 (GRCm39) |
missense |
probably benign |
0.30 |
|
R0032:Mroh2a
|
UTSW |
1 |
88,183,888 (GRCm39) |
frame shift |
probably null |
|
|
R0068:Mroh2a
|
UTSW |
1 |
88,183,888 (GRCm39) |
frame shift |
probably null |
|
|
R0139:Mroh2a
|
UTSW |
1 |
88,185,524 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0197:Mroh2a
|
UTSW |
1 |
88,173,764 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0242:Mroh2a
|
UTSW |
1 |
88,170,142 (GRCm39) |
missense |
possibly damaging |
0.77 |
|
R0322:Mroh2a
|
UTSW |
1 |
88,158,402 (GRCm39) |
nonsense |
probably null |
|
|
R0374:Mroh2a
|
UTSW |
1 |
88,170,142 (GRCm39) |
missense |
possibly damaging |
0.77 |
|
R0387:Mroh2a
|
UTSW |
1 |
88,173,764 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0412:Mroh2a
|
UTSW |
1 |
88,162,938 (GRCm39) |
missense |
probably benign |
0.01 |
|
R0536:Mroh2a
|
UTSW |
1 |
88,186,386 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0548:Mroh2a
|
UTSW |
1 |
88,170,142 (GRCm39) |
missense |
possibly damaging |
0.77 |
|
R0580:Mroh2a
|
UTSW |
1 |
88,171,672 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0581:Mroh2a
|
UTSW |
1 |
88,183,888 (GRCm39) |
frame shift |
probably null |
|
|
R0583:Mroh2a
|
UTSW |
1 |
88,183,888 (GRCm39) |
frame shift |
probably null |
|
|
R0613:Mroh2a
|
UTSW |
1 |
88,171,672 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0652:Mroh2a
|
UTSW |
1 |
88,158,402 (GRCm39) |
nonsense |
probably null |
|
|
R0657:Mroh2a
|
UTSW |
1 |
88,183,287 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0659:Mroh2a
|
UTSW |
1 |
88,170,142 (GRCm39) |
missense |
possibly damaging |
0.77 |
|
R0659:Mroh2a
|
UTSW |
1 |
88,178,064 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0675:Mroh2a
|
UTSW |
1 |
88,178,064 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0675:Mroh2a
|
UTSW |
1 |
88,156,102 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0689:Mroh2a
|
UTSW |
1 |
88,158,402 (GRCm39) |
nonsense |
probably null |
|
|
R0689:Mroh2a
|
UTSW |
1 |
88,186,386 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0735:Mroh2a
|
UTSW |
1 |
88,171,672 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0761:Mroh2a
|
UTSW |
1 |
88,171,672 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0766:Mroh2a
|
UTSW |
1 |
88,158,402 (GRCm39) |
nonsense |
probably null |
|
|
R0845:Mroh2a
|
UTSW |
1 |
88,186,386 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0853:Mroh2a
|
UTSW |
1 |
88,186,386 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0959:Mroh2a
|
UTSW |
1 |
88,159,979 (GRCm39) |
frame shift |
probably null |
|
|
R0960:Mroh2a
|
UTSW |
1 |
88,170,142 (GRCm39) |
missense |
possibly damaging |
0.77 |
|
R1004:Mroh2a
|
UTSW |
1 |
88,170,142 (GRCm39) |
missense |
possibly damaging |
0.77 |
|
R1013:Mroh2a
|
UTSW |
1 |
88,162,334 (GRCm39) |
critical splice donor site |
probably null |
|
|
R1028:Mroh2a
|
UTSW |
1 |
88,163,098 (GRCm39) |
missense |
probably benign |
0.30 |
|
R1268:Mroh2a
|
UTSW |
1 |
88,158,402 (GRCm39) |
nonsense |
probably null |
|
|
R1281:Mroh2a
|
UTSW |
1 |
88,183,889 (GRCm39) |
frame shift |
probably null |
|
|
R1414:Mroh2a
|
UTSW |
1 |
88,186,386 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1439:Mroh2a
|
UTSW |
1 |
88,185,524 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1441:Mroh2a
|
UTSW |
1 |
88,169,353 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R1442:Mroh2a
|
UTSW |
1 |
88,160,075 (GRCm39) |
splice site |
probably benign |
|
|
R1442:Mroh2a
|
UTSW |
1 |
88,170,142 (GRCm39) |
missense |
possibly damaging |
0.77 |
|
R1465:Mroh2a
|
UTSW |
1 |
88,185,524 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1662:Mroh2a
|
UTSW |
1 |
88,169,340 (GRCm39) |
missense |
probably benign |
0.07 |
|
R1686:Mroh2a
|
UTSW |
1 |
88,158,402 (GRCm39) |
nonsense |
probably null |
|
|
R1686:Mroh2a
|
UTSW |
1 |
88,162,334 (GRCm39) |
critical splice donor site |
probably null |
|
|
R1780:Mroh2a
|
UTSW |
1 |
88,158,402 (GRCm39) |
nonsense |
probably null |
|
|
R1846:Mroh2a
|
UTSW |
1 |
88,186,386 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1899:Mroh2a
|
UTSW |
1 |
88,163,098 (GRCm39) |
missense |
probably benign |
0.30 |
|
R1958:Mroh2a
|
UTSW |
1 |
88,165,213 (GRCm39) |
nonsense |
probably null |
|
|
R2122:Mroh2a
|
UTSW |
1 |
88,184,476 (GRCm39) |
missense |
probably benign |
0.37 |
|
R2248:Mroh2a
|
UTSW |
1 |
88,184,476 (GRCm39) |
missense |
probably benign |
0.37 |
|
R2306:Mroh2a
|
UTSW |
1 |
88,186,386 (GRCm39) |
missense |
probably benign |
0.00 |
|
R2869:Mroh2a
|
UTSW |
1 |
88,159,979 (GRCm39) |
frame shift |
probably null |
|
|
R2870:Mroh2a
|
UTSW |
1 |
88,159,979 (GRCm39) |
frame shift |
probably null |
|
|
R2871:Mroh2a
|
UTSW |
1 |
88,183,287 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2872:Mroh2a
|
UTSW |
1 |
88,159,979 (GRCm39) |
frame shift |
probably null |
|
|
R3408:Mroh2a
|
UTSW |
1 |
88,159,979 (GRCm39) |
frame shift |
probably null |
|
|
R3608:Mroh2a
|
UTSW |
1 |
88,172,717 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3730:Mroh2a
|
UTSW |
1 |
88,159,979 (GRCm39) |
frame shift |
probably null |
|
|
R3937:Mroh2a
|
UTSW |
1 |
88,186,386 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4022:Mroh2a
|
UTSW |
1 |
88,173,764 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4049:Mroh2a
|
UTSW |
1 |
88,186,386 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4133:Mroh2a
|
UTSW |
1 |
88,182,687 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R4361:Mroh2a
|
UTSW |
1 |
88,182,687 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R4392:Mroh2a
|
UTSW |
1 |
88,187,311 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4401:Mroh2a
|
UTSW |
1 |
88,182,657 (GRCm39) |
missense |
possibly damaging |
0.72 |
|
R4402:Mroh2a
|
UTSW |
1 |
88,182,657 (GRCm39) |
missense |
possibly damaging |
0.72 |
|
R4575:Mroh2a
|
UTSW |
1 |
88,186,386 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4625:Mroh2a
|
UTSW |
1 |
88,182,687 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R4631:Mroh2a
|
UTSW |
1 |
88,186,386 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4665:Mroh2a
|
UTSW |
1 |
88,169,340 (GRCm39) |
missense |
probably benign |
0.07 |
|
R4701:Mroh2a
|
UTSW |
1 |
88,162,334 (GRCm39) |
critical splice donor site |
probably null |
|
|
R4701:Mroh2a
|
UTSW |
1 |
88,169,340 (GRCm39) |
missense |
probably benign |
0.07 |
|
R4771:Mroh2a
|
UTSW |
1 |
88,179,087 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4795:Mroh2a
|
UTSW |
1 |
88,186,386 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4839:Mroh2a
|
UTSW |
1 |
88,165,666 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4873:Mroh2a
|
UTSW |
1 |
88,182,657 (GRCm39) |
missense |
possibly damaging |
0.72 |
|
R4875:Mroh2a
|
UTSW |
1 |
88,182,657 (GRCm39) |
missense |
possibly damaging |
0.72 |
|
R4896:Mroh2a
|
UTSW |
1 |
88,184,476 (GRCm39) |
missense |
probably benign |
0.37 |
|
R5007:Mroh2a
|
UTSW |
1 |
88,159,979 (GRCm39) |
frame shift |
probably null |
|
|
R5031:Mroh2a
|
UTSW |
1 |
88,159,979 (GRCm39) |
frame shift |
probably null |
|
|
R5062:Mroh2a
|
UTSW |
1 |
88,159,979 (GRCm39) |
frame shift |
probably null |
|
|
R5301:Mroh2a
|
UTSW |
1 |
88,186,386 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5367:Mroh2a
|
UTSW |
1 |
88,182,687 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R5371:Mroh2a
|
UTSW |
1 |
88,186,386 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5446:Mroh2a
|
UTSW |
1 |
88,182,687 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R5484:Mroh2a
|
UTSW |
1 |
88,186,386 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5506:Mroh2a
|
UTSW |
1 |
88,186,386 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5561:Mroh2a
|
UTSW |
1 |
88,159,979 (GRCm39) |
frame shift |
probably null |
|
|
R5615:Mroh2a
|
UTSW |
1 |
88,159,979 (GRCm39) |
frame shift |
probably null |
|
|
R5825:Mroh2a
|
UTSW |
1 |
88,158,402 (GRCm39) |
nonsense |
probably null |
|
|
R5891:Mroh2a
|
UTSW |
1 |
88,169,337 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R5906:Mroh2a
|
UTSW |
1 |
88,186,386 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5928:Mroh2a
|
UTSW |
1 |
88,169,340 (GRCm39) |
missense |
probably benign |
0.07 |
|
R6004:Mroh2a
|
UTSW |
1 |
88,176,377 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6035:Mroh2a
|
UTSW |
1 |
88,158,390 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6064:Mroh2a
|
UTSW |
1 |
88,159,979 (GRCm39) |
frame shift |
probably null |
|
|
R6074:Mroh2a
|
UTSW |
1 |
88,186,386 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6091:Mroh2a
|
UTSW |
1 |
88,159,979 (GRCm39) |
frame shift |
probably null |
|
|
R6127:Mroh2a
|
UTSW |
1 |
88,162,334 (GRCm39) |
critical splice donor site |
probably null |
|
|
R6234:Mroh2a
|
UTSW |
1 |
88,184,476 (GRCm39) |
missense |
probably benign |
0.37 |
|
R6234:Mroh2a
|
UTSW |
1 |
88,162,334 (GRCm39) |
critical splice donor site |
probably null |
|
|
R6244:Mroh2a
|
UTSW |
1 |
88,184,476 (GRCm39) |
missense |
probably benign |
0.37 |
|
R6464:Mroh2a
|
UTSW |
1 |
88,185,524 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6465:Mroh2a
|
UTSW |
1 |
88,159,979 (GRCm39) |
frame shift |
probably null |
|
|
R6575:Mroh2a
|
UTSW |
1 |
88,159,979 (GRCm39) |
frame shift |
probably null |
|
|
R6809:Mroh2a
|
UTSW |
1 |
88,162,938 (GRCm39) |
missense |
probably benign |
0.01 |
|
R6819:Mroh2a
|
UTSW |
1 |
88,170,142 (GRCm39) |
missense |
possibly damaging |
0.77 |
|
R6854:Mroh2a
|
UTSW |
1 |
88,171,672 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6860:Mroh2a
|
UTSW |
1 |
88,182,657 (GRCm39) |
missense |
possibly damaging |
0.72 |
|
R7126:Mroh2a
|
UTSW |
1 |
88,182,657 (GRCm39) |
missense |
possibly damaging |
0.72 |
|
R7818:Mroh2a
|
UTSW |
1 |
88,162,334 (GRCm39) |
critical splice donor site |
probably null |
|
|
R8350:Mroh2a
|
UTSW |
1 |
88,171,805 (GRCm39) |
splice site |
probably null |
|
|
R9414:Mroh2a
|
UTSW |
1 |
88,179,096 (GRCm39) |
missense |
probably benign |
0.26 |
|
RF024:Mroh2a
|
UTSW |
1 |
88,170,207 (GRCm39) |
missense |
probably damaging |
1.00 |
|
V5622:Mroh2a
|
UTSW |
1 |
88,154,813 (GRCm39) |
start gained |
probably benign |
|
|
V8831:Mroh2a
|
UTSW |
1 |
88,183,889 (GRCm39) |
frame shift |
probably null |
|
|
X0027:Mroh2a
|
UTSW |
1 |
88,176,335 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
X0028:Mroh2a
|
UTSW |
1 |
88,183,888 (GRCm39) |
frame shift |
probably null |
|
|
X0028:Mroh2a
|
UTSW |
1 |
88,159,979 (GRCm39) |
frame shift |
probably null |
|
|
X0033:Mroh2a
|
UTSW |
1 |
88,183,888 (GRCm39) |
frame shift |
probably null |
|
|
X0034:Mroh2a
|
UTSW |
1 |
88,183,888 (GRCm39) |
frame shift |
probably null |
|
|
X0034:Mroh2a
|
UTSW |
1 |
88,160,014 (GRCm39) |
missense |
probably damaging |
1.00 |
|
X0034:Mroh2a
|
UTSW |
1 |
88,159,979 (GRCm39) |
frame shift |
probably null |
|
|
X0039:Mroh2a
|
UTSW |
1 |
88,159,979 (GRCm39) |
frame shift |
probably null |
|
|
X0057:Mroh2a
|
UTSW |
1 |
88,183,888 (GRCm39) |
frame shift |
probably null |
|
|
X0057:Mroh2a
|
UTSW |
1 |
88,183,377 (GRCm39) |
missense |
probably benign |
0.25 |
|
X0057:Mroh2a
|
UTSW |
1 |
88,159,979 (GRCm39) |
frame shift |
probably null |
|
|
X0063:Mroh2a
|
UTSW |
1 |
88,159,979 (GRCm39) |
frame shift |
probably null |
|
|
Z1188:Mroh2a
|
UTSW |
1 |
88,162,938 (GRCm39) |
missense |
probably benign |
0.01 |
|
Z1190:Mroh2a
|
UTSW |
1 |
88,159,979 (GRCm39) |
frame shift |
probably null |
|
|
Z1192:Mroh2a
|
UTSW |
1 |
88,162,938 (GRCm39) |
missense |
probably benign |
0.01 |
|
| Predicted Primers |
PCR Primer
(F):5'- ACTCCCAGGTTTGTGGGTAGGAAC -3'
(R):5'- AAAGCACAGGATGACGCCCTTCAG -3'
Sequencing Primer
(F):5'- TAGGAAAGGATTTGGCCTTCAC -3'
(R):5'- ACGCCCTTCAGGGAAGC -3'
|
| Posted On |
2014-07-25 |
Incidental Mutation