Incidental Mutation 'R0606:Atrn'
| ID |
216249 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Atrn
|
| Ensembl Gene |
ENSMUSG00000027312 |
| Gene Name |
attractin |
| Synonyms |
Mgca |
| MMRRC Submission |
038795-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R0606 (G1)
|
| Quality Score |
76 |
|
Status
|
Validated
|
| Chromosome |
2 |
| Chromosomal Location |
130748415-130872253 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to G
at 130748776 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Glutamic Acid to Glycine
at position 99
(E99G)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000028781
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000028781]
[ENSMUST00000146975]
|
| AlphaFold |
Q9WU60 |
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000028781
AA Change: E99G
PolyPhen 2
Score 0.904 (Sensitivity: 0.82; Specificity: 0.94)
|
| SMART Domains |
Protein: ENSMUSP00000028781
Gene: ENSMUSG00000027312
AA Change: E99G
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
2 |
9 |
N/A |
INTRINSIC |
|
low complexity region
|
51 |
97 |
N/A |
INTRINSIC |
|
EGF
|
99 |
129 |
9.85e-5 |
SMART |
|
CUB
|
131 |
247 |
7.85e-18 |
SMART |
|
EGF
|
248 |
282 |
1.47e1 |
SMART |
|
Pfam:Kelch_1
|
339 |
382 |
1.1e-7 |
PFAM |
|
Pfam:Kelch_5
|
389 |
434 |
2.5e-7 |
PFAM |
|
Pfam:Kelch_6
|
390 |
439 |
3.3e-8 |
PFAM |
|
Pfam:Kelch_1
|
553 |
606 |
8.4e-8 |
PFAM |
|
PSI
|
646 |
693 |
7.41e-7 |
SMART |
|
PSI
|
702 |
747 |
8.64e-8 |
SMART |
|
PSI
|
754 |
799 |
2.11e-2 |
SMART |
|
CLECT
|
787 |
918 |
6.14e-20 |
SMART |
|
PSI
|
931 |
982 |
1.11e-5 |
SMART |
|
PSI
|
985 |
1060 |
1.2e-6 |
SMART |
|
EGF_Lam
|
1062 |
1105 |
1.97e-4 |
SMART |
|
EGF_like
|
1108 |
1154 |
3.9e0 |
SMART |
|
transmembrane domain
|
1278 |
1300 |
N/A |
INTRINSIC |
|
low complexity region
|
1310 |
1322 |
N/A |
INTRINSIC |
|
low complexity region
|
1373 |
1385 |
N/A |
INTRINSIC |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000128176
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000133766
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000134964
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000135110
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000146975
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000156982
|
| Meta Mutation Damage Score |
0.0713 |
| Coding Region Coverage |
- 1x: 99.3%
- 3x: 98.8%
- 10x: 97.3%
- 20x: 94.2%
|
| Validation Efficiency |
98% (99/101) |
| MGI Phenotype |
FUNCTION: This gene encodes a widely expressed transmembrane glycoprotein that plays important roles in diverse physiological processes such as regulation of hair pigmentation, monocyte-T cell interaction and control of energy homeostasis. The encoded preproprotein undergoes proteolytic processing to generate a mature, functional protein. Certain mutations in this gene are responsible for the mahogany mouse phenotype of dark brown or black coat on a normally agouti background. Mice with loss-of-function mutations in this gene exhibit black coat color, tremor, adiposity, higher basal metabolic rate, juvenile-onset hypomyelination and age-dependent spongiform neurodegeneration of the central nervous system. [provided by RefSeq, Jul 2016]
PHENOTYPE: Some mutant homozygotes exhibit decreases in phaeomelanin synthesis, body weight, and adiposity; increases in locomotion, and abnormal myelination and vacuolation of the central nervous system resulting in tremors. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 95 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Actl9 |
T |
C |
17: 33,652,572 (GRCm39) |
Y211H |
probably damaging |
Het |
| Actn1 |
A |
T |
12: 80,221,421 (GRCm39) |
|
probably benign |
Het |
| Adtrp |
A |
G |
13: 41,920,881 (GRCm39) |
F197L |
probably damaging |
Het |
| Ankrd11 |
G |
A |
8: 123,619,571 (GRCm39) |
T1406I |
probably benign |
Het |
| Arhgap24 |
A |
T |
5: 103,045,086 (GRCm39) |
R620W |
probably damaging |
Het |
| Atg13 |
A |
G |
2: 91,512,418 (GRCm39) |
Y284H |
probably benign |
Het |
| Cage1 |
A |
T |
13: 38,200,470 (GRCm39) |
|
probably benign |
Het |
| Cblif |
A |
T |
19: 11,729,658 (GRCm39) |
I206F |
possibly damaging |
Het |
| Ccr3 |
T |
A |
9: 123,828,839 (GRCm39) |
M58K |
probably benign |
Het |
| Cdk18 |
G |
T |
1: 132,045,355 (GRCm39) |
|
probably benign |
Het |
| Chst5 |
A |
G |
8: 112,617,551 (GRCm39) |
V23A |
probably benign |
Het |
| Col4a3 |
T |
C |
1: 82,650,307 (GRCm39) |
|
probably benign |
Het |
| Col4a6 |
A |
G |
X: 139,975,219 (GRCm39) |
|
probably benign |
Het |
| Csmd3 |
T |
C |
15: 48,321,058 (GRCm39) |
I251V |
probably benign |
Het |
| Csnk1g3 |
G |
A |
18: 54,050,100 (GRCm39) |
V115M |
probably damaging |
Het |
| Cst7 |
A |
T |
2: 150,412,439 (GRCm39) |
M1L |
probably benign |
Het |
| Cyp4f17 |
A |
T |
17: 32,746,817 (GRCm39) |
D373V |
probably damaging |
Het |
| Dclk2 |
G |
A |
3: 86,813,311 (GRCm39) |
R212W |
probably damaging |
Het |
| Dhrs7b |
T |
G |
11: 60,721,572 (GRCm39) |
|
probably benign |
Het |
| Dhx58 |
T |
A |
11: 100,593,077 (GRCm39) |
H210L |
probably benign |
Het |
| Dnah9 |
T |
C |
11: 65,732,159 (GRCm39) |
Y4249C |
probably damaging |
Het |
| Eif5b |
T |
A |
1: 38,087,974 (GRCm39) |
L990H |
probably damaging |
Het |
| Faap24 |
T |
C |
7: 35,094,388 (GRCm39) |
|
probably benign |
Het |
| Fryl |
T |
A |
5: 73,282,077 (GRCm39) |
H174L |
probably benign |
Het |
| Gabrr1 |
T |
C |
4: 33,132,696 (GRCm39) |
W15R |
probably benign |
Het |
| Gm15446 |
T |
C |
5: 110,091,347 (GRCm39) |
V533A |
probably benign |
Het |
| Gm6760 |
T |
A |
X: 63,195,259 (GRCm39) |
K63* |
probably null |
Het |
| Gne |
C |
T |
4: 44,042,244 (GRCm39) |
E444K |
possibly damaging |
Het |
| Gpr173 |
T |
A |
X: 151,130,036 (GRCm39) |
M146L |
possibly damaging |
Het |
| Hira |
C |
T |
16: 18,753,797 (GRCm39) |
S547L |
probably benign |
Het |
| Hnf1b |
A |
G |
11: 83,754,810 (GRCm39) |
H161R |
probably benign |
Het |
| Hnrnpm |
T |
A |
17: 33,877,364 (GRCm39) |
N53I |
probably damaging |
Het |
| Hs3st5 |
A |
T |
10: 36,708,584 (GRCm39) |
I40F |
probably benign |
Het |
| Hydin |
C |
T |
8: 111,276,430 (GRCm39) |
|
probably benign |
Het |
| Ift172 |
A |
G |
5: 31,411,657 (GRCm39) |
I1607T |
probably damaging |
Het |
| Igfn1 |
T |
C |
1: 135,887,639 (GRCm39) |
Q2475R |
probably damaging |
Het |
| Il6st |
T |
C |
13: 112,640,806 (GRCm39) |
S800P |
possibly damaging |
Het |
| Iqub |
G |
A |
6: 24,501,260 (GRCm39) |
|
probably benign |
Het |
| Itgb1 |
A |
T |
8: 129,448,853 (GRCm39) |
|
probably benign |
Het |
| Kctd21 |
G |
A |
7: 96,996,808 (GRCm39) |
E94K |
probably benign |
Het |
| Kir3dl2 |
A |
G |
X: 135,354,260 (GRCm39) |
V233A |
possibly damaging |
Het |
| Klra2 |
A |
T |
6: 131,197,187 (GRCm39) |
C271S |
probably damaging |
Het |
| Lacc1 |
A |
T |
14: 77,267,061 (GRCm39) |
C401S |
probably damaging |
Het |
| Lmna |
T |
C |
3: 88,389,885 (GRCm39) |
E580G |
probably damaging |
Het |
| Matn2 |
A |
G |
15: 34,345,296 (GRCm39) |
Y101C |
probably damaging |
Het |
| Mrps16 |
G |
A |
14: 20,441,457 (GRCm39) |
R116* |
probably null |
Het |
| Ndrg2 |
G |
T |
14: 52,143,674 (GRCm39) |
R333S |
probably damaging |
Het |
| Nf2 |
A |
G |
11: 4,732,194 (GRCm39) |
I507T |
possibly damaging |
Het |
| Nktr |
A |
G |
9: 121,578,356 (GRCm39) |
|
probably benign |
Het |
| Nkx3-1 |
G |
A |
14: 69,428,455 (GRCm39) |
|
probably benign |
Het |
| Npat |
T |
C |
9: 53,467,781 (GRCm39) |
|
probably null |
Het |
| Nrxn1 |
T |
C |
17: 90,872,801 (GRCm39) |
N1047S |
probably damaging |
Het |
| Nup210 |
A |
T |
6: 91,003,911 (GRCm39) |
I1402N |
possibly damaging |
Het |
| Or5d40 |
G |
T |
2: 88,015,624 (GRCm39) |
M134I |
possibly damaging |
Het |
| Parp14 |
G |
A |
16: 35,677,130 (GRCm39) |
A946V |
probably benign |
Het |
| Pdcl2 |
C |
T |
5: 76,460,328 (GRCm39) |
S182N |
probably benign |
Het |
| Pdia3 |
G |
A |
2: 121,262,858 (GRCm39) |
G275S |
probably damaging |
Het |
| Pla2g4a |
A |
G |
1: 149,716,455 (GRCm39) |
F669L |
probably benign |
Het |
| Plekha8 |
A |
G |
6: 54,606,805 (GRCm39) |
K367E |
probably damaging |
Het |
| Pola1 |
A |
G |
X: 92,531,693 (GRCm39) |
|
probably benign |
Het |
| Ppm1d |
C |
T |
11: 85,236,703 (GRCm39) |
T494I |
probably benign |
Het |
| Pramel16 |
T |
A |
4: 143,676,453 (GRCm39) |
Y217F |
probably benign |
Het |
| Prl6a1 |
A |
T |
13: 27,498,177 (GRCm39) |
|
probably benign |
Het |
| Ptprg |
T |
A |
14: 12,154,131 (GRCm38) |
S617R |
probably benign |
Het |
| R3hdm2 |
G |
A |
10: 127,280,313 (GRCm39) |
G45D |
probably damaging |
Het |
| Rev1 |
T |
A |
1: 38,098,204 (GRCm39) |
R780W |
probably null |
Het |
| Rnf139 |
T |
A |
15: 58,771,676 (GRCm39) |
F567Y |
probably damaging |
Het |
| Scarf1 |
T |
C |
11: 75,405,174 (GRCm39) |
V71A |
probably damaging |
Het |
| Shtn1 |
A |
G |
19: 58,988,372 (GRCm39) |
S438P |
probably damaging |
Het |
| Slc30a3 |
T |
A |
5: 31,246,067 (GRCm39) |
H221L |
probably benign |
Het |
| Smo |
A |
C |
6: 29,753,603 (GRCm39) |
I160L |
possibly damaging |
Het |
| Snapc5 |
A |
T |
9: 64,086,582 (GRCm39) |
|
probably benign |
Het |
| Snf8 |
G |
T |
11: 95,925,799 (GRCm39) |
|
probably benign |
Het |
| Spata31d1a |
T |
C |
13: 59,850,245 (GRCm39) |
S628G |
probably benign |
Het |
| Sphkap |
A |
T |
1: 83,258,145 (GRCm39) |
D199E |
probably damaging |
Het |
| Spring1 |
T |
C |
5: 118,397,154 (GRCm39) |
Y128H |
probably damaging |
Het |
| Stxbp5l |
T |
C |
16: 37,024,883 (GRCm39) |
T572A |
possibly damaging |
Het |
| Thada |
C |
A |
17: 84,723,731 (GRCm39) |
V1108L |
possibly damaging |
Het |
| Tln1 |
T |
C |
4: 43,547,756 (GRCm39) |
Q735R |
probably benign |
Het |
| Trim24 |
G |
A |
6: 37,848,169 (GRCm39) |
E42K |
probably benign |
Het |
| Trnt1 |
T |
A |
6: 106,754,869 (GRCm39) |
|
probably benign |
Het |
| Ttbk2 |
A |
T |
2: 120,604,353 (GRCm39) |
M215K |
probably damaging |
Het |
| Ttc8 |
C |
T |
12: 98,909,718 (GRCm39) |
|
probably benign |
Het |
| Ube3c |
A |
G |
5: 29,795,926 (GRCm39) |
Y105C |
probably damaging |
Het |
| Unc13c |
A |
G |
9: 73,438,265 (GRCm39) |
|
probably benign |
Het |
| Usp36 |
A |
G |
11: 118,153,854 (GRCm39) |
|
probably benign |
Het |
| Vcf2 |
C |
T |
X: 149,181,360 (GRCm39) |
A144T |
probably benign |
Het |
| Vmn2r102 |
T |
C |
17: 19,899,106 (GRCm39) |
S483P |
possibly damaging |
Het |
| Wdr95 |
A |
G |
5: 149,511,595 (GRCm39) |
T432A |
probably damaging |
Het |
| Wnk1 |
G |
T |
6: 119,903,644 (GRCm39) |
P2523H |
probably damaging |
Het |
| Xpo4 |
A |
G |
14: 57,875,665 (GRCm39) |
|
probably benign |
Het |
| Zar1 |
G |
T |
5: 72,737,886 (GRCm39) |
P71Q |
probably damaging |
Het |
| Zbtb41 |
T |
C |
1: 139,351,348 (GRCm39) |
Y154H |
probably benign |
Het |
| Zer1 |
G |
T |
2: 29,994,809 (GRCm39) |
|
probably benign |
Het |
| Zfp454 |
A |
G |
11: 50,765,012 (GRCm39) |
F140S |
probably benign |
Het |
|
| Other mutations in Atrn |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00337:Atrn
|
APN |
2 |
130,799,999 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL00571:Atrn
|
APN |
2 |
130,836,968 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01092:Atrn
|
APN |
2 |
130,789,556 (GRCm39) |
nonsense |
probably null |
|
|
IGL01572:Atrn
|
APN |
2 |
130,844,715 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01924:Atrn
|
APN |
2 |
130,777,485 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02116:Atrn
|
APN |
2 |
130,800,009 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02372:Atrn
|
APN |
2 |
130,844,674 (GRCm39) |
splice site |
probably benign |
|
|
IGL02390:Atrn
|
APN |
2 |
130,862,897 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
IGL02548:Atrn
|
APN |
2 |
130,814,202 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02749:Atrn
|
APN |
2 |
130,789,654 (GRCm39) |
splice site |
probably benign |
|
|
IGL02749:Atrn
|
APN |
2 |
130,812,064 (GRCm39) |
nonsense |
probably null |
|
|
BB010:Atrn
|
UTSW |
2 |
130,836,986 (GRCm39) |
missense |
probably damaging |
1.00 |
|
BB020:Atrn
|
UTSW |
2 |
130,836,986 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0026:Atrn
|
UTSW |
2 |
130,799,840 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0403:Atrn
|
UTSW |
2 |
130,748,779 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0479:Atrn
|
UTSW |
2 |
130,841,085 (GRCm39) |
nonsense |
probably null |
|
|
R0544:Atrn
|
UTSW |
2 |
130,828,746 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0570:Atrn
|
UTSW |
2 |
130,822,054 (GRCm39) |
missense |
probably benign |
0.01 |
|
R0617:Atrn
|
UTSW |
2 |
130,837,005 (GRCm39) |
critical splice donor site |
probably null |
|
|
R0658:Atrn
|
UTSW |
2 |
130,812,147 (GRCm39) |
critical splice donor site |
probably null |
|
|
R1108:Atrn
|
UTSW |
2 |
130,799,834 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1112:Atrn
|
UTSW |
2 |
130,841,081 (GRCm39) |
missense |
probably benign |
0.04 |
|
R1219:Atrn
|
UTSW |
2 |
130,862,927 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R1422:Atrn
|
UTSW |
2 |
130,799,834 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1524:Atrn
|
UTSW |
2 |
130,799,000 (GRCm39) |
missense |
probably benign |
0.15 |
|
R1653:Atrn
|
UTSW |
2 |
130,777,544 (GRCm39) |
missense |
probably benign |
|
|
R1795:Atrn
|
UTSW |
2 |
130,814,208 (GRCm39) |
missense |
probably benign |
|
|
R1807:Atrn
|
UTSW |
2 |
130,824,692 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R1920:Atrn
|
UTSW |
2 |
130,836,971 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1921:Atrn
|
UTSW |
2 |
130,836,971 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1935:Atrn
|
UTSW |
2 |
130,799,955 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1982:Atrn
|
UTSW |
2 |
130,812,142 (GRCm39) |
missense |
probably benign |
|
|
R2000:Atrn
|
UTSW |
2 |
130,777,508 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2143:Atrn
|
UTSW |
2 |
130,799,916 (GRCm39) |
missense |
probably benign |
0.03 |
|
R2336:Atrn
|
UTSW |
2 |
130,799,874 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2679:Atrn
|
UTSW |
2 |
130,803,595 (GRCm39) |
critical splice donor site |
probably null |
|
|
R3426:Atrn
|
UTSW |
2 |
130,862,876 (GRCm39) |
missense |
probably benign |
0.06 |
|
R3909:Atrn
|
UTSW |
2 |
130,836,127 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4077:Atrn
|
UTSW |
2 |
130,806,850 (GRCm39) |
critical splice donor site |
probably null |
|
|
R4162:Atrn
|
UTSW |
2 |
130,836,148 (GRCm39) |
splice site |
probably benign |
|
|
R4195:Atrn
|
UTSW |
2 |
130,775,332 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4364:Atrn
|
UTSW |
2 |
130,812,128 (GRCm39) |
missense |
probably benign |
0.39 |
|
R4465:Atrn
|
UTSW |
2 |
130,802,388 (GRCm39) |
missense |
probably benign |
0.08 |
|
R4510:Atrn
|
UTSW |
2 |
130,777,497 (GRCm39) |
nonsense |
probably null |
|
|
R4511:Atrn
|
UTSW |
2 |
130,777,497 (GRCm39) |
nonsense |
probably null |
|
|
R4527:Atrn
|
UTSW |
2 |
130,815,424 (GRCm39) |
missense |
probably benign |
0.10 |
|
R4586:Atrn
|
UTSW |
2 |
130,823,962 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4592:Atrn
|
UTSW |
2 |
130,841,050 (GRCm39) |
intron |
probably benign |
|
|
R4658:Atrn
|
UTSW |
2 |
130,775,349 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4735:Atrn
|
UTSW |
2 |
130,862,910 (GRCm39) |
missense |
probably benign |
0.06 |
|
R4960:Atrn
|
UTSW |
2 |
130,836,967 (GRCm39) |
nonsense |
probably null |
|
|
R4999:Atrn
|
UTSW |
2 |
130,817,874 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5066:Atrn
|
UTSW |
2 |
130,836,113 (GRCm39) |
missense |
possibly damaging |
0.60 |
|
R5080:Atrn
|
UTSW |
2 |
130,812,044 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R5141:Atrn
|
UTSW |
2 |
130,841,050 (GRCm39) |
intron |
probably benign |
|
|
R5256:Atrn
|
UTSW |
2 |
130,787,939 (GRCm39) |
missense |
probably benign |
0.39 |
|
R5494:Atrn
|
UTSW |
2 |
130,864,995 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5678:Atrn
|
UTSW |
2 |
130,811,936 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R5752:Atrn
|
UTSW |
2 |
130,748,464 (GRCm39) |
unclassified |
probably benign |
|
|
R5931:Atrn
|
UTSW |
2 |
130,775,356 (GRCm39) |
missense |
possibly damaging |
0.56 |
|
R6023:Atrn
|
UTSW |
2 |
130,862,900 (GRCm39) |
missense |
probably benign |
0.25 |
|
R6176:Atrn
|
UTSW |
2 |
130,788,011 (GRCm39) |
missense |
probably benign |
0.31 |
|
R6377:Atrn
|
UTSW |
2 |
130,821,889 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6433:Atrn
|
UTSW |
2 |
130,864,947 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7226:Atrn
|
UTSW |
2 |
130,828,664 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7402:Atrn
|
UTSW |
2 |
130,789,520 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7541:Atrn
|
UTSW |
2 |
130,803,491 (GRCm39) |
missense |
possibly damaging |
0.46 |
|
R7587:Atrn
|
UTSW |
2 |
130,822,034 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7872:Atrn
|
UTSW |
2 |
130,812,147 (GRCm39) |
critical splice donor site |
probably null |
|
|
R7910:Atrn
|
UTSW |
2 |
130,806,807 (GRCm39) |
missense |
probably benign |
0.04 |
|
R7913:Atrn
|
UTSW |
2 |
130,812,131 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7933:Atrn
|
UTSW |
2 |
130,836,986 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8044:Atrn
|
UTSW |
2 |
130,777,449 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8079:Atrn
|
UTSW |
2 |
130,855,561 (GRCm39) |
missense |
probably null |
1.00 |
|
R8093:Atrn
|
UTSW |
2 |
130,817,908 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8203:Atrn
|
UTSW |
2 |
130,802,469 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8234:Atrn
|
UTSW |
2 |
130,864,920 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R8462:Atrn
|
UTSW |
2 |
130,777,504 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8816:Atrn
|
UTSW |
2 |
130,846,494 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8816:Atrn
|
UTSW |
2 |
130,748,798 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8831:Atrn
|
UTSW |
2 |
130,748,521 (GRCm39) |
missense |
probably benign |
0.22 |
|
R8937:Atrn
|
UTSW |
2 |
130,841,157 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9161:Atrn
|
UTSW |
2 |
130,777,470 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9722:Atrn
|
UTSW |
2 |
130,803,536 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9786:Atrn
|
UTSW |
2 |
130,786,809 (GRCm39) |
missense |
probably damaging |
1.00 |
|
RF009:Atrn
|
UTSW |
2 |
130,748,842 (GRCm39) |
missense |
probably benign |
0.12 |
|
X0024:Atrn
|
UTSW |
2 |
130,800,059 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1088:Atrn
|
UTSW |
2 |
130,815,319 (GRCm39) |
missense |
probably benign |
|
|
Z1176:Atrn
|
UTSW |
2 |
130,788,113 (GRCm39) |
missense |
probably benign |
0.27 |
|
Z1177:Atrn
|
UTSW |
2 |
130,787,962 (GRCm39) |
missense |
probably damaging |
0.99 |
|
| Predicted Primers |
PCR Primer
(F):5'- TAGGCGATGTTCATCCGCGCTAAG -3'
(R):5'- AGCCATCATCAAACACAGTGGGG -3'
Sequencing Primer
(F):5'- AAGATggtggcggtggc -3'
(R):5'- ACAGTGGGGCAAATTCTACC -3'
|
| Posted On |
2014-07-31 |
Incidental Mutation