Incidental Mutation 'R1964:Magi3'
| ID |
217071 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Magi3
|
| Ensembl Gene |
ENSMUSG00000052539 |
| Gene Name |
membrane associated guanylate kinase, WW and PDZ domain containing 3 |
| Synonyms |
4732496O19Rik, 6530407C02Rik |
| MMRRC Submission |
039977-MU
|
| Accession Numbers |
|
| Essential gene? |
Possibly non essential
(E-score: 0.435)
|
| Stock # |
R1964 (G1)
|
| Quality Score |
180 |
|
Status
|
Not validated
|
| Chromosome |
3 |
| Chromosomal Location |
103920575-104127690 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to G
at 103927718 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Valine to Alanine
at position 1023
(V1023A)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000113713
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000064371]
[ENSMUST00000121198]
[ENSMUST00000122303]
[ENSMUST00000145727]
|
| AlphaFold |
no structure available at present |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000064371
AA Change: V1023A
PolyPhen 2
Score 0.989 (Sensitivity: 0.72; Specificity: 0.97)
|
| SMART Domains |
Protein: ENSMUSP00000067932
Gene: ENSMUSG00000052539
AA Change: V1023A
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
2 |
14 |
N/A |
INTRINSIC |
|
PDZ
|
27 |
108 |
1.94e-1 |
SMART |
|
GuKc
|
114 |
281 |
8.56e-10 |
SMART |
|
WW
|
297 |
329 |
9.14e-12 |
SMART |
|
WW
|
343 |
375 |
2.47e-8 |
SMART |
|
PDZ
|
421 |
497 |
1.48e-17 |
SMART |
|
PDZ
|
589 |
659 |
3.07e-10 |
SMART |
|
low complexity region
|
664 |
674 |
N/A |
INTRINSIC |
|
low complexity region
|
683 |
698 |
N/A |
INTRINSIC |
|
PDZ
|
737 |
813 |
1.34e-15 |
SMART |
|
PDZ
|
861 |
939 |
7.65e-20 |
SMART |
|
PDZ
|
1030 |
1104 |
1.55e-20 |
SMART |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000121198
AA Change: V1023A
PolyPhen 2
Score 0.989 (Sensitivity: 0.72; Specificity: 0.97)
|
| SMART Domains |
Protein: ENSMUSP00000112934
Gene: ENSMUSG00000052539
AA Change: V1023A
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
2 |
14 |
N/A |
INTRINSIC |
|
PDZ
|
27 |
108 |
1.94e-1 |
SMART |
|
GuKc
|
114 |
281 |
8.56e-10 |
SMART |
|
WW
|
297 |
329 |
9.14e-12 |
SMART |
|
WW
|
343 |
375 |
2.47e-8 |
SMART |
|
PDZ
|
421 |
497 |
1.48e-17 |
SMART |
|
PDZ
|
589 |
659 |
3.07e-10 |
SMART |
|
low complexity region
|
664 |
674 |
N/A |
INTRINSIC |
|
low complexity region
|
683 |
698 |
N/A |
INTRINSIC |
|
PDZ
|
737 |
813 |
1.34e-15 |
SMART |
|
PDZ
|
861 |
939 |
7.65e-20 |
SMART |
|
PDZ
|
1030 |
1104 |
1.55e-20 |
SMART |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000122303
AA Change: V1023A
PolyPhen 2
Score 0.989 (Sensitivity: 0.72; Specificity: 0.97)
|
| SMART Domains |
Protein: ENSMUSP00000113713
Gene: ENSMUSG00000052539
AA Change: V1023A
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
2 |
14 |
N/A |
INTRINSIC |
|
PDZ
|
27 |
108 |
1.94e-1 |
SMART |
|
GuKc
|
114 |
281 |
8.56e-10 |
SMART |
|
WW
|
297 |
329 |
9.14e-12 |
SMART |
|
WW
|
343 |
375 |
2.47e-8 |
SMART |
|
PDZ
|
421 |
497 |
1.48e-17 |
SMART |
|
PDZ
|
589 |
659 |
3.07e-10 |
SMART |
|
low complexity region
|
664 |
674 |
N/A |
INTRINSIC |
|
low complexity region
|
683 |
698 |
N/A |
INTRINSIC |
|
PDZ
|
737 |
813 |
1.34e-15 |
SMART |
|
PDZ
|
861 |
939 |
7.65e-20 |
SMART |
|
PDZ
|
1030 |
1104 |
1.55e-20 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000145727
|
| SMART Domains |
Protein: ENSMUSP00000114722
Gene: ENSMUSG00000058388
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:Phtf-FEM1B_bdg
|
3 |
158 |
1.6e-88 |
PFAM |
|
low complexity region
|
170 |
181 |
N/A |
INTRINSIC |
|
low complexity region
|
347 |
370 |
N/A |
INTRINSIC |
|
transmembrane domain
|
473 |
492 |
N/A |
INTRINSIC |
|
transmembrane domain
|
512 |
534 |
N/A |
INTRINSIC |
|
transmembrane domain
|
610 |
632 |
N/A |
INTRINSIC |
|
transmembrane domain
|
647 |
664 |
N/A |
INTRINSIC |
|
| Coding Region Coverage |
- 1x: 99.1%
- 3x: 98.5%
- 10x: 96.8%
- 20x: 94.1%
|
| Validation Efficiency |
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 96 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 1700010I14Rik |
C |
T |
17: 9,211,324 (GRCm39) |
H158Y |
probably damaging |
Het |
| 1810009J06Rik |
T |
A |
6: 40,945,141 (GRCm39) |
C207S |
probably damaging |
Het |
| Aadac |
T |
A |
3: 59,944,759 (GRCm39) |
|
probably null |
Het |
| Abca6 |
T |
A |
11: 110,075,502 (GRCm39) |
I1330F |
probably damaging |
Het |
| Adar |
A |
T |
3: 89,653,202 (GRCm39) |
S263C |
probably benign |
Het |
| Adra2b |
T |
C |
2: 127,205,734 (GRCm39) |
Y84H |
probably damaging |
Het |
| Arnt2 |
A |
T |
7: 83,992,997 (GRCm39) |
V181E |
possibly damaging |
Het |
| Atg7 |
T |
C |
6: 114,683,191 (GRCm39) |
L418P |
probably damaging |
Het |
| Atp2c1 |
A |
G |
9: 105,323,322 (GRCm39) |
L181P |
probably damaging |
Het |
| Awat2 |
G |
A |
X: 99,448,165 (GRCm39) |
P148S |
probably damaging |
Het |
| Birc6 |
A |
G |
17: 74,941,880 (GRCm39) |
M2737V |
possibly damaging |
Het |
| Ccdc81 |
A |
G |
7: 89,535,361 (GRCm39) |
C292R |
probably benign |
Het |
| Cd14 |
T |
A |
18: 36,859,392 (GRCm39) |
E21V |
probably damaging |
Het |
| Cdc14b |
A |
C |
13: 64,363,351 (GRCm39) |
C303W |
probably damaging |
Het |
| Cdh23 |
T |
C |
10: 60,221,001 (GRCm39) |
I1248V |
probably benign |
Het |
| Ceacam1 |
T |
C |
7: 25,174,133 (GRCm39) |
D174G |
probably benign |
Het |
| Cgas |
T |
G |
9: 78,344,737 (GRCm39) |
Y228S |
probably damaging |
Het |
| Chd7 |
A |
G |
4: 8,865,978 (GRCm39) |
M717V |
probably damaging |
Het |
| Cib1 |
T |
C |
7: 79,882,120 (GRCm39) |
T20A |
possibly damaging |
Het |
| Clec4d |
A |
G |
6: 123,239,319 (GRCm39) |
K9R |
probably benign |
Het |
| Cntnap1 |
C |
A |
11: 101,068,850 (GRCm39) |
S131* |
probably null |
Het |
| Crybg1 |
T |
C |
10: 43,834,326 (GRCm39) |
K1581R |
probably damaging |
Het |
| Csf2 |
T |
G |
11: 54,139,284 (GRCm39) |
T100P |
probably benign |
Het |
| Csrp2 |
T |
A |
10: 110,767,894 (GRCm39) |
D26E |
probably benign |
Het |
| Cul1 |
T |
C |
6: 47,479,505 (GRCm39) |
V257A |
probably damaging |
Het |
| Cul4a |
G |
A |
8: 13,186,406 (GRCm39) |
M505I |
possibly damaging |
Het |
| Cul4a |
T |
C |
8: 13,186,854 (GRCm39) |
M530T |
probably benign |
Het |
| Dcp2 |
T |
C |
18: 44,529,038 (GRCm39) |
M51T |
possibly damaging |
Het |
| Ddx60 |
T |
A |
8: 62,401,903 (GRCm39) |
C260S |
probably benign |
Het |
| Dennd2c |
G |
A |
3: 103,073,807 (GRCm39) |
R851H |
probably damaging |
Het |
| Dnah11 |
T |
C |
12: 118,106,027 (GRCm39) |
E625G |
possibly damaging |
Het |
| Edem1 |
T |
C |
6: 108,821,908 (GRCm39) |
W322R |
probably benign |
Het |
| Egflam |
T |
C |
15: 7,276,586 (GRCm39) |
T527A |
probably damaging |
Het |
| Ephb1 |
T |
A |
9: 101,848,322 (GRCm39) |
M659L |
possibly damaging |
Het |
| Fbxl2 |
A |
G |
9: 113,818,237 (GRCm39) |
I203T |
probably benign |
Het |
| Gabbr1 |
G |
A |
17: 37,359,351 (GRCm39) |
G109R |
probably damaging |
Het |
| Gabra2 |
T |
C |
5: 71,171,793 (GRCm39) |
I148V |
possibly damaging |
Het |
| Golga1 |
A |
G |
2: 38,937,099 (GRCm39) |
V161A |
probably benign |
Het |
| Gps2 |
T |
G |
11: 69,807,246 (GRCm39) |
S301A |
probably benign |
Het |
| H2-D1 |
T |
C |
17: 35,482,595 (GRCm39) |
L105P |
probably benign |
Het |
| Igdcc4 |
T |
C |
9: 65,030,051 (GRCm39) |
V367A |
probably benign |
Het |
| Igkv4-69 |
T |
G |
6: 69,260,782 (GRCm39) |
Y115S |
probably benign |
Het |
| Itga5 |
A |
G |
15: 103,262,741 (GRCm39) |
L309P |
probably damaging |
Het |
| Itih1 |
A |
G |
14: 30,651,580 (GRCm39) |
Y871H |
probably damaging |
Het |
| Itpr2 |
T |
A |
6: 146,013,191 (GRCm39) |
N2662I |
probably damaging |
Het |
| Kctd19 |
T |
A |
8: 106,115,102 (GRCm39) |
E486D |
probably damaging |
Het |
| Kif5b |
C |
T |
18: 6,209,059 (GRCm39) |
R901Q |
possibly damaging |
Het |
| Kmt2a |
G |
A |
9: 44,731,941 (GRCm39) |
S2792F |
probably benign |
Het |
| Mapk9 |
C |
A |
11: 49,745,160 (GRCm39) |
R25S |
probably null |
Het |
| Memo1 |
T |
C |
17: 74,552,003 (GRCm39) |
T98A |
possibly damaging |
Het |
| Mill2 |
A |
G |
7: 18,590,529 (GRCm39) |
K203R |
probably damaging |
Het |
| Mios |
T |
A |
6: 8,215,798 (GRCm39) |
H331Q |
probably damaging |
Het |
| Muc6 |
G |
T |
7: 141,226,329 (GRCm39) |
S1566* |
probably null |
Het |
| Muc6 |
A |
G |
7: 141,226,330 (GRCm39) |
|
probably benign |
Het |
| Napsa |
T |
C |
7: 44,231,109 (GRCm39) |
F113L |
probably benign |
Het |
| Or5ac16 |
T |
A |
16: 59,022,271 (GRCm39) |
I173F |
possibly damaging |
Het |
| Or9m1 |
A |
G |
2: 87,734,011 (GRCm39) |
V3A |
probably benign |
Het |
| Oscp1 |
T |
G |
4: 125,977,415 (GRCm39) |
V226G |
possibly damaging |
Het |
| Osgin2 |
G |
T |
4: 15,998,358 (GRCm39) |
S421R |
probably damaging |
Het |
| Pclaf |
A |
G |
9: 65,800,677 (GRCm39) |
N50D |
probably damaging |
Het |
| Pdgfc |
A |
T |
3: 81,082,292 (GRCm39) |
I162F |
probably benign |
Het |
| Plag1 |
T |
C |
4: 3,903,956 (GRCm39) |
T412A |
probably benign |
Het |
| Pogz |
A |
T |
3: 94,785,504 (GRCm39) |
T820S |
probably benign |
Het |
| Ptpn9 |
T |
A |
9: 56,967,196 (GRCm39) |
V473D |
probably damaging |
Het |
| Qdpr |
A |
T |
5: 45,596,660 (GRCm39) |
M66K |
possibly damaging |
Het |
| Qrich1 |
A |
G |
9: 108,411,621 (GRCm39) |
N382S |
possibly damaging |
Het |
| Rbbp8 |
T |
C |
18: 11,875,736 (GRCm39) |
V883A |
possibly damaging |
Het |
| Rgl1 |
T |
A |
1: 152,424,855 (GRCm39) |
I375F |
probably damaging |
Het |
| Rif1 |
C |
T |
2: 51,988,421 (GRCm39) |
T720I |
probably benign |
Het |
| Rilp |
A |
T |
11: 75,401,328 (GRCm39) |
Q95L |
probably benign |
Het |
| Rnf169 |
T |
A |
7: 99,574,732 (GRCm39) |
N621I |
probably damaging |
Het |
| Rps27a |
T |
C |
11: 29,497,229 (GRCm39) |
K27R |
probably null |
Het |
| Sar1a |
T |
C |
10: 61,520,947 (GRCm39) |
V54A |
probably benign |
Het |
| Sash1 |
T |
A |
10: 8,605,477 (GRCm39) |
H971L |
probably benign |
Het |
| Sdk2 |
G |
A |
11: 113,671,843 (GRCm39) |
Q2102* |
probably null |
Het |
| Serpina1e |
T |
A |
12: 103,917,466 (GRCm39) |
I68F |
probably damaging |
Het |
| Serpinb9e |
A |
C |
13: 33,437,474 (GRCm39) |
Q119P |
probably benign |
Het |
| Sh3tc2 |
A |
T |
18: 62,124,226 (GRCm39) |
K965* |
probably null |
Het |
| Slc16a1 |
A |
T |
3: 104,556,782 (GRCm39) |
S56C |
probably damaging |
Het |
| Slc26a11 |
T |
A |
11: 119,271,020 (GRCm39) |
L563Q |
possibly damaging |
Het |
| Smarca2 |
G |
T |
19: 26,650,124 (GRCm39) |
E24* |
probably null |
Het |
| Smgc |
G |
A |
15: 91,744,468 (GRCm39) |
G239D |
probably damaging |
Het |
| Sos2 |
A |
T |
12: 69,663,636 (GRCm39) |
M616K |
possibly damaging |
Het |
| Tet1 |
T |
A |
10: 62,648,726 (GRCm39) |
D1902V |
possibly damaging |
Het |
| Thap2 |
C |
T |
10: 115,220,152 (GRCm39) |
C10Y |
probably damaging |
Het |
| Tln2 |
T |
C |
9: 67,249,417 (GRCm39) |
D890G |
probably benign |
Het |
| Tor2a |
G |
A |
2: 32,648,716 (GRCm39) |
G62D |
probably damaging |
Het |
| Ubqln5 |
A |
T |
7: 103,778,095 (GRCm39) |
V243E |
possibly damaging |
Het |
| Utrn |
A |
T |
10: 12,560,181 (GRCm39) |
D1369E |
probably damaging |
Het |
| Vcan |
A |
G |
13: 89,840,861 (GRCm39) |
V1561A |
probably benign |
Het |
| Vmn1r70 |
T |
C |
7: 10,367,737 (GRCm39) |
F56S |
possibly damaging |
Het |
| Vmn2r25 |
A |
G |
6: 123,800,254 (GRCm39) |
L696S |
possibly damaging |
Het |
| Washc2 |
A |
G |
6: 116,185,948 (GRCm39) |
T53A |
probably damaging |
Het |
| Wnk1 |
T |
A |
6: 119,911,343 (GRCm39) |
T2417S |
possibly damaging |
Het |
| Zbtb49 |
A |
T |
5: 38,361,105 (GRCm39) |
C12* |
probably null |
Het |
| Zfp472 |
C |
A |
17: 33,196,848 (GRCm39) |
P308T |
possibly damaging |
Het |
|
| Other mutations in Magi3 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00429:Magi3
|
APN |
3 |
103,922,294 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL00933:Magi3
|
APN |
3 |
103,923,163 (GRCm39) |
missense |
probably benign |
|
|
IGL01151:Magi3
|
APN |
3 |
103,958,690 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01674:Magi3
|
APN |
3 |
104,013,037 (GRCm39) |
splice site |
probably benign |
|
|
IGL01790:Magi3
|
APN |
3 |
103,992,560 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01903:Magi3
|
APN |
3 |
103,958,526 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
IGL01939:Magi3
|
APN |
3 |
103,961,778 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL02142:Magi3
|
APN |
3 |
103,923,219 (GRCm39) |
missense |
probably benign |
0.32 |
|
IGL02183:Magi3
|
APN |
3 |
103,992,663 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL02887:Magi3
|
APN |
3 |
104,002,473 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03071:Magi3
|
APN |
3 |
103,923,202 (GRCm39) |
missense |
possibly damaging |
0.51 |
|
IGL03085:Magi3
|
APN |
3 |
103,922,655 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
IGL03192:Magi3
|
APN |
3 |
103,950,562 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03204:Magi3
|
APN |
3 |
104,013,151 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03227:Magi3
|
APN |
3 |
103,958,435 (GRCm39) |
missense |
probably benign |
|
|
IGL03388:Magi3
|
APN |
3 |
103,923,157 (GRCm39) |
missense |
probably benign |
0.30 |
|
PIT4280001:Magi3
|
UTSW |
3 |
103,961,668 (GRCm39) |
missense |
probably damaging |
1.00 |
|
PIT4504001:Magi3
|
UTSW |
3 |
103,922,842 (GRCm39) |
missense |
probably benign |
0.05 |
|
R0092:Magi3
|
UTSW |
3 |
103,958,280 (GRCm39) |
nonsense |
probably null |
|
|
R0514:Magi3
|
UTSW |
3 |
103,922,338 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0569:Magi3
|
UTSW |
3 |
103,923,358 (GRCm39) |
missense |
probably benign |
0.43 |
|
R0608:Magi3
|
UTSW |
3 |
103,924,873 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0920:Magi3
|
UTSW |
3 |
103,941,507 (GRCm39) |
splice site |
probably null |
|
|
R1173:Magi3
|
UTSW |
3 |
103,968,946 (GRCm39) |
critical splice donor site |
probably null |
|
|
R1256:Magi3
|
UTSW |
3 |
103,935,126 (GRCm39) |
missense |
probably benign |
0.08 |
|
R1391:Magi3
|
UTSW |
3 |
103,922,374 (GRCm39) |
nonsense |
probably null |
|
|
R1559:Magi3
|
UTSW |
3 |
103,954,169 (GRCm39) |
splice site |
probably benign |
|
|
R1568:Magi3
|
UTSW |
3 |
103,996,843 (GRCm39) |
missense |
probably benign |
0.02 |
|
R1631:Magi3
|
UTSW |
3 |
103,958,493 (GRCm39) |
missense |
probably benign |
0.05 |
|
R1747:Magi3
|
UTSW |
3 |
103,941,489 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
R1930:Magi3
|
UTSW |
3 |
103,996,920 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2151:Magi3
|
UTSW |
3 |
103,992,554 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2151:Magi3
|
UTSW |
3 |
103,954,198 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2266:Magi3
|
UTSW |
3 |
103,928,382 (GRCm39) |
intron |
probably benign |
|
|
R2267:Magi3
|
UTSW |
3 |
103,928,382 (GRCm39) |
intron |
probably benign |
|
|
R2268:Magi3
|
UTSW |
3 |
103,928,382 (GRCm39) |
intron |
probably benign |
|
|
R2519:Magi3
|
UTSW |
3 |
103,923,081 (GRCm39) |
missense |
probably benign |
0.00 |
|
R3104:Magi3
|
UTSW |
3 |
103,958,636 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R3105:Magi3
|
UTSW |
3 |
103,958,636 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R3619:Magi3
|
UTSW |
3 |
103,961,721 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4158:Magi3
|
UTSW |
3 |
103,958,277 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4160:Magi3
|
UTSW |
3 |
103,958,277 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4284:Magi3
|
UTSW |
3 |
103,923,184 (GRCm39) |
nonsense |
probably null |
|
|
R4285:Magi3
|
UTSW |
3 |
103,923,184 (GRCm39) |
nonsense |
probably null |
|
|
R4397:Magi3
|
UTSW |
3 |
104,127,030 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4512:Magi3
|
UTSW |
3 |
103,996,871 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4676:Magi3
|
UTSW |
3 |
103,923,141 (GRCm39) |
missense |
probably benign |
|
|
R4758:Magi3
|
UTSW |
3 |
103,922,637 (GRCm39) |
missense |
probably benign |
0.01 |
|
R4940:Magi3
|
UTSW |
3 |
103,958,708 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5039:Magi3
|
UTSW |
3 |
104,013,107 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5160:Magi3
|
UTSW |
3 |
103,935,224 (GRCm39) |
missense |
possibly damaging |
0.46 |
|
R5422:Magi3
|
UTSW |
3 |
103,958,684 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5509:Magi3
|
UTSW |
3 |
103,922,818 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5839:Magi3
|
UTSW |
3 |
104,127,047 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5924:Magi3
|
UTSW |
3 |
103,961,854 (GRCm39) |
splice site |
probably null |
|
|
R6018:Magi3
|
UTSW |
3 |
104,013,128 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6189:Magi3
|
UTSW |
3 |
103,958,181 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6235:Magi3
|
UTSW |
3 |
103,923,384 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6244:Magi3
|
UTSW |
3 |
103,923,013 (GRCm39) |
missense |
probably benign |
0.16 |
|
R6258:Magi3
|
UTSW |
3 |
103,996,912 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6358:Magi3
|
UTSW |
3 |
103,958,268 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6534:Magi3
|
UTSW |
3 |
103,992,536 (GRCm39) |
missense |
possibly damaging |
0.75 |
|
R6806:Magi3
|
UTSW |
3 |
103,954,285 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R6816:Magi3
|
UTSW |
3 |
103,997,227 (GRCm39) |
splice site |
probably null |
|
|
R6897:Magi3
|
UTSW |
3 |
103,996,873 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7011:Magi3
|
UTSW |
3 |
104,013,070 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7039:Magi3
|
UTSW |
3 |
103,958,699 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7196:Magi3
|
UTSW |
3 |
103,956,484 (GRCm39) |
missense |
probably benign |
0.01 |
|
R7237:Magi3
|
UTSW |
3 |
103,935,227 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7285:Magi3
|
UTSW |
3 |
103,941,430 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7709:Magi3
|
UTSW |
3 |
103,941,354 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7724:Magi3
|
UTSW |
3 |
103,923,243 (GRCm39) |
missense |
probably benign |
0.04 |
|
R7797:Magi3
|
UTSW |
3 |
103,958,618 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7950:Magi3
|
UTSW |
3 |
103,924,005 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8140:Magi3
|
UTSW |
3 |
103,941,402 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8204:Magi3
|
UTSW |
3 |
103,958,502 (GRCm39) |
missense |
probably benign |
|
|
R8229:Magi3
|
UTSW |
3 |
103,923,018 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8229:Magi3
|
UTSW |
3 |
103,923,017 (GRCm39) |
missense |
possibly damaging |
0.79 |
|
R8260:Magi3
|
UTSW |
3 |
103,922,625 (GRCm39) |
missense |
probably benign |
0.01 |
|
R8348:Magi3
|
UTSW |
3 |
103,958,531 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8368:Magi3
|
UTSW |
3 |
104,002,379 (GRCm39) |
critical splice donor site |
probably null |
|
|
R8543:Magi3
|
UTSW |
3 |
104,126,984 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R8762:Magi3
|
UTSW |
3 |
103,958,169 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8826:Magi3
|
UTSW |
3 |
103,992,662 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8847:Magi3
|
UTSW |
3 |
103,922,334 (GRCm39) |
missense |
probably benign |
0.09 |
|
R8892:Magi3
|
UTSW |
3 |
103,958,141 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8939:Magi3
|
UTSW |
3 |
103,996,748 (GRCm39) |
intron |
probably benign |
|
|
R9090:Magi3
|
UTSW |
3 |
103,923,264 (GRCm39) |
missense |
possibly damaging |
0.68 |
|
R9187:Magi3
|
UTSW |
3 |
103,923,073 (GRCm39) |
missense |
possibly damaging |
0.76 |
|
R9271:Magi3
|
UTSW |
3 |
103,923,264 (GRCm39) |
missense |
possibly damaging |
0.68 |
|
R9433:Magi3
|
UTSW |
3 |
103,922,473 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9439:Magi3
|
UTSW |
3 |
103,922,473 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9557:Magi3
|
UTSW |
3 |
103,924,933 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9557:Magi3
|
UTSW |
3 |
103,922,473 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9697:Magi3
|
UTSW |
3 |
103,956,458 (GRCm39) |
critical splice donor site |
probably null |
|
|
R9796:Magi3
|
UTSW |
3 |
103,928,291 (GRCm39) |
missense |
probably benign |
|
|
X0026:Magi3
|
UTSW |
3 |
103,927,736 (GRCm39) |
missense |
probably benign |
0.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- TGTAAGGGGTTTCTGCATTCCC -3'
(R):5'- TTTATGACAGTTAAGTAGCAGCCC -3'
Sequencing Primer
(F):5'- TCTAGAACTTTCCAGCCTAGAGG -3'
(R):5'- GCCCCAGCTAGCATTCC -3'
|
| Posted On |
2014-08-01 |
Incidental Mutation