Incidental Mutation 'R1958:Mical2'
| ID |
218025 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Mical2
|
| Ensembl Gene |
ENSMUSG00000038244 |
| Gene Name |
microtubule associated monooxygenase, calponin and LIM domain containing 2 |
| Synonyms |
4921517J23Rik, Ebitein1, 5330438E18Rik, Micalcl |
| MMRRC Submission |
039972-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.242)
|
| Stock # |
R1958 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
|
| Chromosome |
7 |
| Chromosomal Location |
111825063-112012313 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to G
at 111980311 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Aspartic acid to Glycine
at position 161
(D161G)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000033033
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000033033]
[ENSMUST00000051308]
[ENSMUST00000106645]
|
| AlphaFold |
Q8BML1
Q9D5U9 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000033033
AA Change: D161G
PolyPhen 2
Score 0.002 (Sensitivity: 0.99; Specificity: 0.30)
|
| SMART Domains |
Protein: ENSMUSP00000033033
Gene: ENSMUSG00000030771
AA Change: D161G
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
8 |
18 |
N/A |
INTRINSIC |
|
low complexity region
|
72 |
100 |
N/A |
INTRINSIC |
|
low complexity region
|
393 |
404 |
N/A |
INTRINSIC |
|
low complexity region
|
415 |
432 |
N/A |
INTRINSIC |
|
low complexity region
|
545 |
562 |
N/A |
INTRINSIC |
|
coiled coil region
|
569 |
597 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000051308
AA Change: D95G
PolyPhen 2
Score 0.001 (Sensitivity: 0.99; Specificity: 0.15)
|
| SMART Domains |
Protein: ENSMUSP00000062443
Gene: ENSMUSG00000030771
AA Change: D95G
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
6 |
34 |
N/A |
INTRINSIC |
|
low complexity region
|
327 |
338 |
N/A |
INTRINSIC |
|
low complexity region
|
349 |
366 |
N/A |
INTRINSIC |
|
low complexity region
|
479 |
496 |
N/A |
INTRINSIC |
|
low complexity region
|
500 |
515 |
N/A |
INTRINSIC |
|
DUF3585
|
526 |
668 |
6.86e-56 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000106645
AA Change: D95G
PolyPhen 2
Score 0.001 (Sensitivity: 0.99; Specificity: 0.15)
|
| SMART Domains |
Protein: ENSMUSP00000102256
Gene: ENSMUSG00000030771
AA Change: D95G
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
6 |
34 |
N/A |
INTRINSIC |
|
low complexity region
|
327 |
338 |
N/A |
INTRINSIC |
|
low complexity region
|
349 |
366 |
N/A |
INTRINSIC |
|
low complexity region
|
479 |
496 |
N/A |
INTRINSIC |
|
low complexity region
|
500 |
515 |
N/A |
INTRINSIC |
|
DUF3585
|
526 |
668 |
6.86e-56 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000213108
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000215412
|
| Predicted Effect |
unknown
Transcript: ENSMUST00000216652
AA Change: D307G
|
| Meta Mutation Damage Score |
0.0898 |
| Coding Region Coverage |
- 1x: 99.2%
- 3x: 98.5%
- 10x: 96.7%
- 20x: 94.0%
|
| Validation Efficiency |
97% (99/102) |
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] The protein encoded by this gene is a monooxygenase that enhances depolymerization of F-actin and is therefore involved in cytoskeletal dynamics. The encoded protein is a regulator of the SRF signaling pathway. Increased expression of this gene has been associated with cancer progression and metastasis. [provided by RefSeq, Oct 2016]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 100 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 4933430I17Rik |
A |
T |
4: 62,457,146 (GRCm39) |
N155I |
probably benign |
Het |
| Abca14 |
A |
G |
7: 119,924,382 (GRCm39) |
Y1678C |
probably damaging |
Het |
| Adamts19 |
A |
T |
18: 59,103,078 (GRCm39) |
R706S |
probably benign |
Het |
| Adipor1 |
T |
C |
1: 134,350,771 (GRCm39) |
S7P |
probably benign |
Het |
| Adss2 |
A |
G |
1: 177,597,544 (GRCm39) |
I372T |
probably damaging |
Het |
| Arhgap15 |
T |
A |
2: 44,133,136 (GRCm39) |
D347E |
possibly damaging |
Het |
| Arnt |
C |
T |
3: 95,355,704 (GRCm39) |
S16L |
possibly damaging |
Het |
| Asb8 |
T |
C |
15: 98,034,097 (GRCm39) |
T153A |
possibly damaging |
Het |
| Aspscr1 |
G |
T |
11: 120,580,034 (GRCm39) |
G191V |
probably null |
Het |
| Atm |
T |
C |
9: 53,382,718 (GRCm39) |
H1957R |
probably damaging |
Het |
| Atp13a5 |
A |
G |
16: 29,133,419 (GRCm39) |
Y411H |
probably damaging |
Het |
| Cadm1 |
T |
G |
9: 47,761,633 (GRCm39) |
I411S |
probably damaging |
Het |
| Cdh23 |
T |
A |
10: 60,246,652 (GRCm39) |
M927L |
probably benign |
Het |
| Cdk15 |
A |
T |
1: 59,383,475 (GRCm39) |
R423W |
probably damaging |
Het |
| Cep250 |
T |
A |
2: 155,818,301 (GRCm39) |
|
probably null |
Het |
| Cfap43 |
T |
A |
19: 47,885,649 (GRCm39) |
Y322F |
probably benign |
Het |
| Cfap54 |
T |
C |
10: 92,833,204 (GRCm39) |
S1141G |
probably benign |
Het |
| Clnk |
T |
C |
5: 38,863,969 (GRCm39) |
Y428C |
possibly damaging |
Het |
| Cnksr1 |
A |
G |
4: 133,955,727 (GRCm39) |
S668P |
probably benign |
Het |
| Cpxm2 |
A |
T |
7: 131,663,876 (GRCm39) |
I349N |
probably damaging |
Het |
| Csmd3 |
A |
G |
15: 47,868,035 (GRCm39) |
|
probably null |
Het |
| Cstdc3 |
T |
C |
16: 36,132,927 (GRCm39) |
L68P |
possibly damaging |
Het |
| Dnmt1 |
C |
T |
9: 20,838,442 (GRCm39) |
R207H |
probably benign |
Het |
| Dph2 |
A |
T |
4: 117,749,041 (GRCm39) |
F5I |
probably damaging |
Het |
| Dst |
T |
A |
1: 34,202,802 (GRCm39) |
F325L |
probably damaging |
Het |
| Edem3 |
T |
C |
1: 151,680,076 (GRCm39) |
L474S |
probably damaging |
Het |
| Emilin1 |
T |
A |
5: 31,075,160 (GRCm39) |
L467Q |
probably benign |
Het |
| Fam170a |
G |
A |
18: 50,415,181 (GRCm39) |
E276K |
probably benign |
Het |
| Farp1 |
A |
T |
14: 121,456,787 (GRCm39) |
|
probably null |
Het |
| Fbrs |
A |
T |
7: 127,085,163 (GRCm39) |
T584S |
possibly damaging |
Het |
| Fbxo22 |
T |
A |
9: 55,116,626 (GRCm39) |
|
probably null |
Het |
| Fhod3 |
T |
G |
18: 25,223,522 (GRCm39) |
L956R |
probably damaging |
Het |
| Fmo4 |
G |
A |
1: 162,631,259 (GRCm39) |
T236I |
probably benign |
Het |
| Foxp4 |
C |
T |
17: 48,186,796 (GRCm39) |
R378Q |
unknown |
Het |
| Gdf10 |
G |
A |
14: 33,654,710 (GRCm39) |
A406T |
probably benign |
Het |
| Gm11444 |
A |
T |
11: 85,738,999 (GRCm39) |
|
probably benign |
Het |
| Gm14443 |
T |
C |
2: 175,011,497 (GRCm39) |
I316M |
probably benign |
Het |
| Has3 |
A |
T |
8: 107,605,435 (GRCm39) |
Y547F |
probably benign |
Het |
| Hdhd2 |
A |
G |
18: 77,052,841 (GRCm39) |
T164A |
probably benign |
Het |
| Hoxb9 |
T |
A |
11: 96,162,880 (GRCm39) |
D171E |
possibly damaging |
Het |
| Hpx |
A |
G |
7: 105,245,603 (GRCm39) |
Y118H |
probably damaging |
Het |
| Iqsec1 |
T |
C |
6: 90,647,441 (GRCm39) |
K858E |
probably damaging |
Het |
| Kifc1 |
G |
A |
17: 34,103,685 (GRCm39) |
R195C |
probably benign |
Het |
| Lama2 |
C |
A |
10: 26,857,594 (GRCm39) |
R3085L |
probably damaging |
Het |
| Lyst |
C |
A |
13: 13,791,203 (GRCm39) |
A22E |
probably damaging |
Het |
| Man2a1 |
T |
C |
17: 65,057,830 (GRCm39) |
F1079L |
probably benign |
Het |
| Marco |
C |
T |
1: 120,412,593 (GRCm39) |
G303R |
probably damaging |
Het |
| Marveld2 |
A |
C |
13: 100,733,858 (GRCm39) |
I536R |
probably damaging |
Het |
| Mcm5 |
A |
G |
8: 75,848,257 (GRCm39) |
D502G |
probably benign |
Het |
| Mdga1 |
A |
T |
17: 30,059,862 (GRCm39) |
L653Q |
probably damaging |
Het |
| Mroh2a |
C |
T |
1: 88,165,213 (GRCm39) |
R445* |
probably null |
Het |
| Mrpl46 |
A |
T |
7: 78,431,146 (GRCm39) |
|
probably null |
Het |
| Nckipsd |
C |
A |
9: 108,691,863 (GRCm39) |
|
probably null |
Het |
| Nek11 |
T |
C |
9: 105,170,916 (GRCm39) |
D373G |
probably benign |
Het |
| Nle1 |
G |
A |
11: 82,795,068 (GRCm39) |
S321F |
probably benign |
Het |
| Noxa1 |
A |
G |
2: 24,980,620 (GRCm39) |
S130P |
probably damaging |
Het |
| Or10a5 |
A |
G |
7: 106,635,478 (GRCm39) |
T39A |
possibly damaging |
Het |
| Or51v14 |
T |
A |
7: 103,260,618 (GRCm39) |
*314L |
probably null |
Het |
| Or5l13 |
A |
T |
2: 87,779,809 (GRCm39) |
L256H |
probably damaging |
Het |
| Or8b39 |
T |
A |
9: 37,996,419 (GRCm39) |
C96S |
probably damaging |
Het |
| Parp3 |
T |
G |
9: 106,352,021 (GRCm39) |
|
probably null |
Het |
| Pask |
A |
T |
1: 93,249,180 (GRCm39) |
I740N |
probably benign |
Het |
| Pelp1 |
A |
G |
11: 70,289,347 (GRCm39) |
F221S |
probably damaging |
Het |
| Pkd1l1 |
T |
G |
11: 8,824,161 (GRCm39) |
K1135Q |
probably benign |
Het |
| Plcl2 |
A |
T |
17: 50,915,109 (GRCm39) |
Q706L |
probably damaging |
Het |
| Psg26 |
T |
C |
7: 18,212,264 (GRCm39) |
T364A |
probably benign |
Het |
| Ptprb |
C |
T |
10: 116,177,441 (GRCm39) |
T1047M |
probably benign |
Het |
| Ptpro |
T |
A |
6: 137,420,592 (GRCm39) |
V1007D |
probably damaging |
Het |
| Rab37 |
C |
T |
11: 115,051,177 (GRCm39) |
A155V |
probably damaging |
Het |
| Rbbp6 |
A |
C |
7: 122,601,168 (GRCm39) |
|
probably benign |
Het |
| Rbmxl2 |
A |
G |
7: 106,809,405 (GRCm39) |
D230G |
probably benign |
Het |
| Rsf1 |
CGGCGGCGGCGGCGGCGGCGGCGGCGGC |
CGGCGGCGGCGGCGGCGGCGGCGGCGGCGGCGGCGGC |
7: 97,229,115 (GRCm39) |
|
probably benign |
Het |
| Sass6 |
G |
T |
3: 116,403,945 (GRCm39) |
K194N |
possibly damaging |
Het |
| Sgpp1 |
T |
G |
12: 75,782,222 (GRCm39) |
D39A |
probably benign |
Het |
| Shank3 |
T |
C |
15: 89,387,351 (GRCm39) |
V198A |
probably damaging |
Het |
| Sin3a |
T |
A |
9: 57,012,893 (GRCm39) |
S591T |
probably damaging |
Het |
| Slc12a6 |
C |
T |
2: 112,185,503 (GRCm39) |
T924I |
possibly damaging |
Het |
| Sln |
T |
A |
9: 53,760,785 (GRCm39) |
I10N |
probably benign |
Het |
| St3gal3 |
A |
T |
4: 117,797,268 (GRCm39) |
M309K |
probably damaging |
Het |
| Syne2 |
T |
A |
12: 76,016,319 (GRCm39) |
D3301E |
probably benign |
Het |
| Tgtp2 |
A |
G |
11: 48,949,919 (GRCm39) |
S218P |
probably damaging |
Het |
| Tha1 |
C |
T |
11: 117,760,179 (GRCm39) |
|
probably benign |
Het |
| Tmem102 |
A |
G |
11: 69,695,225 (GRCm39) |
V249A |
probably benign |
Het |
| Top3b |
G |
A |
16: 16,702,166 (GRCm39) |
E268K |
possibly damaging |
Het |
| Trip4 |
T |
C |
9: 65,746,307 (GRCm39) |
S530G |
possibly damaging |
Het |
| Tut1 |
T |
A |
19: 8,936,677 (GRCm39) |
V167E |
probably damaging |
Het |
| Tut4 |
A |
T |
4: 108,412,903 (GRCm39) |
S1535C |
probably damaging |
Het |
| Ube2u |
A |
T |
4: 100,338,833 (GRCm39) |
M33L |
probably benign |
Het |
| Unc79 |
T |
C |
12: 102,957,621 (GRCm39) |
I12T |
probably damaging |
Het |
| Unc79 |
A |
T |
12: 103,041,178 (GRCm39) |
D737V |
probably benign |
Het |
| Vmn1r26 |
A |
G |
6: 57,985,286 (GRCm39) |
V301A |
probably benign |
Het |
| Vmn1r86 |
A |
G |
7: 12,836,621 (GRCm39) |
V35A |
possibly damaging |
Het |
| Vmn2r98 |
A |
C |
17: 19,286,680 (GRCm39) |
N393H |
possibly damaging |
Het |
| Vps13b |
T |
G |
15: 35,878,835 (GRCm39) |
S2945A |
probably damaging |
Het |
| Whrn |
C |
T |
4: 63,353,666 (GRCm39) |
R367H |
possibly damaging |
Het |
| Zfp235 |
A |
T |
7: 23,839,771 (GRCm39) |
L133F |
probably damaging |
Het |
| Zfp74 |
T |
C |
7: 29,635,136 (GRCm39) |
T191A |
probably benign |
Het |
| Zfp943 |
A |
T |
17: 22,211,979 (GRCm39) |
K355I |
probably damaging |
Het |
| Zranb1 |
T |
G |
7: 132,584,458 (GRCm39) |
S601R |
probably damaging |
Het |
| Zscan29 |
A |
T |
2: 121,000,289 (GRCm39) |
|
probably null |
Het |
|
| Other mutations in Mical2 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00504:Mical2
|
APN |
7 |
111,981,352 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
IGL00886:Mical2
|
APN |
7 |
111,914,279 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL00934:Mical2
|
APN |
7 |
111,948,610 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL00941:Mical2
|
APN |
7 |
111,920,652 (GRCm39) |
splice site |
probably benign |
|
|
IGL01020:Mical2
|
APN |
7 |
111,914,283 (GRCm39) |
splice site |
probably benign |
|
|
IGL01395:Mical2
|
APN |
7 |
111,922,792 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01658:Mical2
|
APN |
7 |
111,914,205 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01775:Mical2
|
APN |
7 |
111,981,269 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
IGL02040:Mical2
|
APN |
7 |
111,910,613 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02051:Mical2
|
APN |
7 |
111,980,597 (GRCm39) |
missense |
probably benign |
0.30 |
|
IGL02388:Mical2
|
APN |
7 |
111,934,620 (GRCm39) |
missense |
probably benign |
|
|
IGL02551:Mical2
|
APN |
7 |
111,923,197 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL02578:Mical2
|
APN |
7 |
111,950,580 (GRCm39) |
missense |
probably benign |
0.05 |
|
IGL02751:Mical2
|
APN |
7 |
111,931,243 (GRCm39) |
missense |
probably benign |
0.11 |
|
IGL03114:Mical2
|
APN |
7 |
111,996,764 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0091:Mical2
|
UTSW |
7 |
111,980,503 (GRCm39) |
missense |
probably benign |
0.05 |
|
R0101:Mical2
|
UTSW |
7 |
111,936,074 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
R0415:Mical2
|
UTSW |
7 |
111,980,235 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0504:Mical2
|
UTSW |
7 |
111,870,524 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0594:Mical2
|
UTSW |
7 |
111,917,657 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R0609:Mical2
|
UTSW |
7 |
111,920,647 (GRCm39) |
splice site |
probably null |
|
|
R0962:Mical2
|
UTSW |
7 |
111,979,624 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1521:Mical2
|
UTSW |
7 |
111,980,817 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1542:Mical2
|
UTSW |
7 |
111,908,675 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1611:Mical2
|
UTSW |
7 |
111,980,671 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1740:Mical2
|
UTSW |
7 |
111,933,043 (GRCm39) |
missense |
probably benign |
|
|
R1815:Mical2
|
UTSW |
7 |
112,012,109 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1855:Mical2
|
UTSW |
7 |
111,944,489 (GRCm39) |
missense |
probably benign |
0.21 |
|
R1962:Mical2
|
UTSW |
7 |
112,012,051 (GRCm39) |
missense |
probably benign |
0.14 |
|
R2086:Mical2
|
UTSW |
7 |
111,917,810 (GRCm39) |
missense |
probably benign |
0.31 |
|
R2136:Mical2
|
UTSW |
7 |
111,870,722 (GRCm39) |
missense |
possibly damaging |
0.72 |
|
R2418:Mical2
|
UTSW |
7 |
111,919,941 (GRCm39) |
critical splice donor site |
probably null |
|
|
R2439:Mical2
|
UTSW |
7 |
111,994,002 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R3053:Mical2
|
UTSW |
7 |
111,910,630 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3979:Mical2
|
UTSW |
7 |
112,006,885 (GRCm39) |
splice site |
probably null |
|
|
R4308:Mical2
|
UTSW |
7 |
111,931,199 (GRCm39) |
missense |
probably benign |
0.27 |
|
R4551:Mical2
|
UTSW |
7 |
111,981,123 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
R4583:Mical2
|
UTSW |
7 |
112,012,154 (GRCm39) |
missense |
probably benign |
0.02 |
|
R4663:Mical2
|
UTSW |
7 |
111,927,884 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
R4868:Mical2
|
UTSW |
7 |
111,917,831 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4902:Mical2
|
UTSW |
7 |
111,936,107 (GRCm39) |
missense |
probably benign |
|
|
R5112:Mical2
|
UTSW |
7 |
111,919,818 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5459:Mical2
|
UTSW |
7 |
111,981,444 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5487:Mical2
|
UTSW |
7 |
111,919,842 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5563:Mical2
|
UTSW |
7 |
111,914,185 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5763:Mical2
|
UTSW |
7 |
111,973,861 (GRCm39) |
critical splice donor site |
probably null |
|
|
R5817:Mical2
|
UTSW |
7 |
111,922,866 (GRCm39) |
missense |
probably benign |
|
|
R5987:Mical2
|
UTSW |
7 |
111,934,155 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6042:Mical2
|
UTSW |
7 |
111,979,619 (GRCm39) |
missense |
probably benign |
0.40 |
|
R6087:Mical2
|
UTSW |
7 |
111,917,692 (GRCm39) |
nonsense |
probably null |
|
|
R6189:Mical2
|
UTSW |
7 |
112,012,087 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6209:Mical2
|
UTSW |
7 |
111,923,293 (GRCm39) |
splice site |
probably null |
|
|
R6311:Mical2
|
UTSW |
7 |
111,922,765 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6319:Mical2
|
UTSW |
7 |
111,927,884 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
R6578:Mical2
|
UTSW |
7 |
111,910,652 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6750:Mical2
|
UTSW |
7 |
111,981,046 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R6782:Mical2
|
UTSW |
7 |
111,945,968 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6798:Mical2
|
UTSW |
7 |
111,975,266 (GRCm39) |
utr 3 prime |
probably benign |
|
|
R7061:Mical2
|
UTSW |
7 |
111,946,008 (GRCm39) |
missense |
probably benign |
0.10 |
|
R7147:Mical2
|
UTSW |
7 |
111,922,810 (GRCm39) |
missense |
possibly damaging |
0.77 |
|
R7260:Mical2
|
UTSW |
7 |
111,919,001 (GRCm39) |
missense |
probably benign |
0.10 |
|
R7266:Mical2
|
UTSW |
7 |
111,902,963 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7347:Mical2
|
UTSW |
7 |
111,981,358 (GRCm39) |
missense |
probably benign |
0.01 |
|
R7391:Mical2
|
UTSW |
7 |
111,919,816 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7724:Mical2
|
UTSW |
7 |
111,922,833 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7747:Mical2
|
UTSW |
7 |
111,933,046 (GRCm39) |
missense |
probably benign |
0.02 |
|
R7783:Mical2
|
UTSW |
7 |
112,012,183 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7818:Mical2
|
UTSW |
7 |
111,944,514 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7824:Mical2
|
UTSW |
7 |
112,006,844 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7995:Mical2
|
UTSW |
7 |
111,980,975 (GRCm39) |
missense |
probably benign |
0.31 |
|
R8022:Mical2
|
UTSW |
7 |
111,902,974 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8429:Mical2
|
UTSW |
7 |
111,944,460 (GRCm39) |
missense |
probably benign |
0.01 |
|
R8505:Mical2
|
UTSW |
7 |
111,919,007 (GRCm39) |
missense |
probably benign |
0.02 |
|
R8532:Mical2
|
UTSW |
7 |
111,917,751 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8830:Mical2
|
UTSW |
7 |
111,980,403 (GRCm39) |
missense |
probably benign |
0.01 |
|
R8862:Mical2
|
UTSW |
7 |
111,910,574 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8906:Mical2
|
UTSW |
7 |
111,980,671 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8988:Mical2
|
UTSW |
7 |
111,910,661 (GRCm39) |
missense |
possibly damaging |
0.63 |
|
R9006:Mical2
|
UTSW |
7 |
111,981,323 (GRCm39) |
missense |
probably benign |
0.13 |
|
R9123:Mical2
|
UTSW |
7 |
111,870,589 (GRCm39) |
missense |
possibly damaging |
0.61 |
|
R9127:Mical2
|
UTSW |
7 |
111,870,589 (GRCm39) |
missense |
possibly damaging |
0.61 |
|
R9128:Mical2
|
UTSW |
7 |
111,870,589 (GRCm39) |
missense |
possibly damaging |
0.61 |
|
R9129:Mical2
|
UTSW |
7 |
111,870,589 (GRCm39) |
missense |
possibly damaging |
0.61 |
|
R9140:Mical2
|
UTSW |
7 |
112,006,826 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9187:Mical2
|
UTSW |
7 |
111,902,797 (GRCm39) |
nonsense |
probably null |
|
|
R9233:Mical2
|
UTSW |
7 |
111,981,399 (GRCm39) |
missense |
probably benign |
0.05 |
|
R9304:Mical2
|
UTSW |
7 |
111,980,974 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R9310:Mical2
|
UTSW |
7 |
111,950,920 (GRCm39) |
missense |
probably benign |
0.45 |
|
R9377:Mical2
|
UTSW |
7 |
111,981,246 (GRCm39) |
missense |
probably benign |
0.10 |
|
R9399:Mical2
|
UTSW |
7 |
111,946,082 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9457:Mical2
|
UTSW |
7 |
112,010,665 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R9500:Mical2
|
UTSW |
7 |
111,936,054 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R9620:Mical2
|
UTSW |
7 |
111,980,403 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9652:Mical2
|
UTSW |
7 |
111,945,996 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9657:Mical2
|
UTSW |
7 |
111,921,806 (GRCm39) |
missense |
probably benign |
0.37 |
|
R9756:Mical2
|
UTSW |
7 |
111,902,928 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9789:Mical2
|
UTSW |
7 |
111,945,996 (GRCm39) |
missense |
probably damaging |
1.00 |
|
RF008:Mical2
|
UTSW |
7 |
111,922,833 (GRCm39) |
missense |
probably damaging |
1.00 |
|
X0062:Mical2
|
UTSW |
7 |
111,946,050 (GRCm39) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- CAATATTTCTGCCCACTCCCATAGG -3'
(R):5'- TCTTTGGACAGCTCTGGTCC -3'
Sequencing Primer
(F):5'- TAGGTGCCAGCTTACAACCTC -3'
(R):5'- AGCTCTGGTCCACCTGGTTG -3'
|
| Posted On |
2014-08-01 |
Incidental Mutation