Incidental Mutation 'R0135:Ttc3'
| ID |
21913 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Ttc3
|
| Ensembl Gene |
ENSMUSG00000040785 |
| Gene Name |
tetratricopeptide repeat domain 3 |
| Synonyms |
D16Ium21e, TPRD, 2610202A04Rik, D16Ium21 |
| MMRRC Submission |
038420-MU
|
| Accession Numbers |
|
| Essential gene? |
Possibly essential
(E-score: 0.574)
|
| Stock # |
R0135 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
(trace)
|
| Chromosome |
16 |
| Chromosomal Location |
94171479-94270081 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to G
at 94263127 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Asparagine to Aspartic acid
at position 1498
(N1498D)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000156137
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000117648]
[ENSMUST00000154196]
[ENSMUST00000211314]
[ENSMUST00000231569]
[ENSMUST00000232660]
[ENSMUST00000232395]
[ENSMUST00000231915]
|
| AlphaFold |
no structure available at present |
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000117648
AA Change: N1853D
PolyPhen 2
Score 0.873 (Sensitivity: 0.83; Specificity: 0.93)
|
| SMART Domains |
Protein: ENSMUSP00000112801
Gene: ENSMUSG00000040785
AA Change: N1853D
| Domain | Start | End | E-Value | Type |
|---|
|
TPR
|
231 |
264 |
3.61e-2 |
SMART |
|
TPR
|
265 |
298 |
3.32e-1 |
SMART |
|
Blast:TPR
|
300 |
332 |
2e-12 |
BLAST |
|
low complexity region
|
444 |
459 |
N/A |
INTRINSIC |
|
TPR
|
576 |
609 |
2.55e-2 |
SMART |
|
low complexity region
|
720 |
732 |
N/A |
INTRINSIC |
|
coiled coil region
|
765 |
796 |
N/A |
INTRINSIC |
|
low complexity region
|
1018 |
1032 |
N/A |
INTRINSIC |
|
low complexity region
|
1036 |
1050 |
N/A |
INTRINSIC |
|
low complexity region
|
1170 |
1190 |
N/A |
INTRINSIC |
|
low complexity region
|
1248 |
1260 |
N/A |
INTRINSIC |
|
low complexity region
|
1278 |
1291 |
N/A |
INTRINSIC |
|
coiled coil region
|
1472 |
1570 |
N/A |
INTRINSIC |
|
low complexity region
|
1876 |
1887 |
N/A |
INTRINSIC |
|
RING
|
1931 |
1970 |
7e-9 |
SMART |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000129536
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000131429
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000141192
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000154196
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000211314
|
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000231569
AA Change: N1498D
PolyPhen 2
Score 0.921 (Sensitivity: 0.81; Specificity: 0.94)
|
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000232660
AA Change: N1853D
PolyPhen 2
Score 0.873 (Sensitivity: 0.83; Specificity: 0.93)
|
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000232395
AA Change: N1853D
PolyPhen 2
Score 0.873 (Sensitivity: 0.83; Specificity: 0.93)
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000231915
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000232368
|
| Meta Mutation Damage Score |
0.0626 |
| Coding Region Coverage |
- 1x: 99.0%
- 3x: 98.3%
- 10x: 96.5%
- 20x: 93.6%
|
| Validation Efficiency |
100% (80/80) |
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 78 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 4932438H23Rik |
A |
G |
16: 90,852,515 (GRCm39) |
F207S |
probably damaging |
Het |
| Abhd8 |
T |
A |
8: 71,910,718 (GRCm39) |
K363N |
probably benign |
Het |
| Adam11 |
T |
A |
11: 102,667,399 (GRCm39) |
V653E |
probably damaging |
Het |
| Adam18 |
T |
C |
8: 25,155,558 (GRCm39) |
S154G |
possibly damaging |
Het |
| Adamts1 |
T |
C |
16: 85,595,591 (GRCm39) |
|
probably benign |
Het |
| Afm |
G |
T |
5: 90,698,181 (GRCm39) |
V528L |
probably benign |
Het |
| Alox12b |
C |
T |
11: 69,053,574 (GRCm39) |
H145Y |
probably benign |
Het |
| Ankmy2 |
C |
A |
12: 36,220,434 (GRCm39) |
|
probably benign |
Het |
| Aox3 |
G |
A |
1: 58,164,247 (GRCm39) |
|
probably benign |
Het |
| Arhgap28 |
T |
C |
17: 68,171,583 (GRCm39) |
D396G |
probably damaging |
Het |
| B430203G13Rik |
T |
C |
12: 17,974,489 (GRCm39) |
|
noncoding transcript |
Het |
| Bean1 |
C |
T |
8: 104,943,807 (GRCm39) |
P121S |
probably damaging |
Het |
| Bok |
T |
C |
1: 93,614,229 (GRCm39) |
S21P |
probably damaging |
Het |
| Brwd1 |
A |
C |
16: 95,848,304 (GRCm39) |
N572K |
probably damaging |
Het |
| C5ar1 |
A |
T |
7: 15,982,864 (GRCm39) |
V52E |
probably damaging |
Het |
| Cblif |
G |
T |
19: 11,735,118 (GRCm39) |
C246F |
probably damaging |
Het |
| Cdr2l |
C |
A |
11: 115,284,497 (GRCm39) |
P278T |
probably damaging |
Het |
| Cnga4 |
T |
A |
7: 105,056,055 (GRCm39) |
I219N |
probably damaging |
Het |
| Cpne2 |
C |
T |
8: 95,281,553 (GRCm39) |
|
probably benign |
Het |
| D430041D05Rik |
A |
G |
2: 104,085,379 (GRCm39) |
S1057P |
possibly damaging |
Het |
| Def8 |
G |
A |
8: 124,183,234 (GRCm39) |
A278T |
probably damaging |
Het |
| Dgcr2 |
A |
G |
16: 17,676,306 (GRCm39) |
S152P |
probably damaging |
Het |
| Dstyk |
A |
T |
1: 132,390,672 (GRCm39) |
D828V |
probably damaging |
Het |
| Eml2 |
T |
C |
7: 18,937,877 (GRCm39) |
S582P |
probably damaging |
Het |
| Engase |
T |
C |
11: 118,375,304 (GRCm39) |
Y359H |
possibly damaging |
Het |
| Fat3 |
T |
C |
9: 15,918,073 (GRCm39) |
D1450G |
probably damaging |
Het |
| Fbxw8 |
A |
T |
5: 118,208,552 (GRCm39) |
I467N |
probably damaging |
Het |
| Fhdc1 |
A |
T |
3: 84,352,925 (GRCm39) |
Y767N |
probably damaging |
Het |
| Flii |
T |
C |
11: 60,614,204 (GRCm39) |
D105G |
probably damaging |
Het |
| Gaa |
C |
T |
11: 119,169,716 (GRCm39) |
T590I |
probably benign |
Het |
| Gabrr1 |
T |
A |
4: 33,160,224 (GRCm39) |
S303T |
probably damaging |
Het |
| Garre1 |
T |
C |
7: 33,945,382 (GRCm39) |
I499M |
probably damaging |
Het |
| Glp1r |
A |
G |
17: 31,143,551 (GRCm39) |
I196V |
probably benign |
Het |
| Grm6 |
G |
A |
11: 50,744,050 (GRCm39) |
E174K |
probably damaging |
Het |
| Helz2 |
A |
C |
2: 180,874,062 (GRCm39) |
L2144R |
probably damaging |
Het |
| Itpr1 |
A |
T |
6: 108,465,443 (GRCm39) |
|
probably benign |
Het |
| Kcns1 |
A |
T |
2: 164,006,875 (GRCm39) |
S363T |
possibly damaging |
Het |
| Kif13a |
A |
T |
13: 46,947,419 (GRCm39) |
V855E |
probably damaging |
Het |
| Krt42 |
T |
C |
11: 100,153,985 (GRCm39) |
T424A |
possibly damaging |
Het |
| Lct |
A |
T |
1: 128,212,860 (GRCm39) |
F1931Y |
probably damaging |
Het |
| Lrp1b |
A |
T |
2: 41,159,251 (GRCm39) |
V1563E |
probably damaging |
Het |
| Lrrc37 |
C |
A |
11: 103,508,873 (GRCm39) |
|
probably benign |
Het |
| Lzts2 |
T |
C |
19: 45,014,626 (GRCm39) |
|
probably benign |
Het |
| Mamdc4 |
C |
T |
2: 25,456,932 (GRCm39) |
R615Q |
possibly damaging |
Het |
| Mei1 |
C |
T |
15: 81,956,170 (GRCm39) |
Q133* |
probably null |
Het |
| Mif4gd |
T |
C |
11: 115,499,291 (GRCm39) |
E197G |
probably damaging |
Het |
| Ncdn |
A |
T |
4: 126,640,462 (GRCm39) |
S544T |
probably benign |
Het |
| Nfat5 |
C |
T |
8: 108,065,707 (GRCm39) |
R156W |
probably damaging |
Het |
| Or52a5 |
T |
A |
7: 103,426,970 (GRCm39) |
D194V |
probably damaging |
Het |
| Padi6 |
T |
C |
4: 140,464,663 (GRCm39) |
T114A |
probably benign |
Het |
| Pigk |
G |
T |
3: 152,450,343 (GRCm39) |
|
probably benign |
Het |
| Pkd1 |
T |
A |
17: 24,784,045 (GRCm39) |
F197Y |
possibly damaging |
Het |
| Pld5 |
A |
T |
1: 175,798,155 (GRCm39) |
F415I |
probably damaging |
Het |
| Pnpla5 |
A |
G |
15: 83,998,150 (GRCm39) |
L364P |
probably damaging |
Het |
| Prrc2c |
G |
A |
1: 162,543,052 (GRCm39) |
|
probably benign |
Het |
| Rab32 |
C |
T |
10: 10,426,584 (GRCm39) |
D121N |
probably damaging |
Het |
| Rab44 |
A |
T |
17: 29,357,106 (GRCm39) |
T79S |
probably benign |
Het |
| Reln |
G |
T |
5: 22,333,647 (GRCm39) |
N258K |
probably damaging |
Het |
| Retsat |
A |
G |
6: 72,579,755 (GRCm39) |
T177A |
probably damaging |
Het |
| Serpinf2 |
T |
A |
11: 75,327,219 (GRCm39) |
H236L |
probably damaging |
Het |
| Slc26a6 |
A |
T |
9: 108,737,794 (GRCm39) |
|
probably benign |
Het |
| Slitrk1 |
T |
A |
14: 109,149,061 (GRCm39) |
E550V |
probably benign |
Het |
| Smarcd3 |
A |
T |
5: 24,800,497 (GRCm39) |
|
probably benign |
Het |
| Spdye4a |
A |
C |
5: 143,210,857 (GRCm39) |
|
probably null |
Het |
| Susd2 |
C |
T |
10: 75,474,348 (GRCm39) |
G572D |
probably damaging |
Het |
| Tcaf3 |
C |
T |
6: 42,566,692 (GRCm39) |
R799K |
probably benign |
Het |
| Tg |
A |
G |
15: 66,566,719 (GRCm39) |
S1256G |
probably benign |
Het |
| Them4 |
A |
T |
3: 94,230,877 (GRCm39) |
|
probably benign |
Het |
| Tmem210 |
C |
T |
2: 25,178,480 (GRCm39) |
A47V |
probably damaging |
Het |
| Tnfrsf1b |
A |
G |
4: 144,955,616 (GRCm39) |
Y47H |
probably benign |
Het |
| Tnik |
T |
G |
3: 28,661,394 (GRCm39) |
N598K |
possibly damaging |
Het |
| Ttll4 |
C |
A |
1: 74,719,087 (GRCm39) |
H313N |
possibly damaging |
Het |
| Vipr2 |
A |
G |
12: 116,106,447 (GRCm39) |
I348V |
probably benign |
Het |
| Vps13a |
A |
G |
19: 16,758,129 (GRCm39) |
V2A |
probably damaging |
Het |
| Vps72 |
G |
A |
3: 95,026,508 (GRCm39) |
R151K |
probably damaging |
Het |
| Zfp106 |
A |
G |
2: 120,350,968 (GRCm39) |
V1561A |
probably damaging |
Het |
| Zfp658 |
C |
A |
7: 43,223,019 (GRCm39) |
Y431* |
probably null |
Het |
| Zkscan2 |
T |
C |
7: 123,079,864 (GRCm39) |
K698E |
possibly damaging |
Het |
|
| Other mutations in Ttc3 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00944:Ttc3
|
APN |
16 |
94,227,620 (GRCm39) |
splice site |
probably null |
|
|
IGL00979:Ttc3
|
APN |
16 |
94,257,577 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01520:Ttc3
|
APN |
16 |
94,191,066 (GRCm39) |
missense |
probably benign |
0.04 |
|
IGL01663:Ttc3
|
APN |
16 |
94,210,590 (GRCm39) |
critical splice donor site |
probably null |
|
|
IGL01720:Ttc3
|
APN |
16 |
94,186,228 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL01736:Ttc3
|
APN |
16 |
94,243,386 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL02045:Ttc3
|
APN |
16 |
94,210,540 (GRCm39) |
splice site |
probably benign |
|
|
IGL02203:Ttc3
|
APN |
16 |
94,219,457 (GRCm39) |
splice site |
probably benign |
|
|
IGL02327:Ttc3
|
APN |
16 |
94,248,967 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02794:Ttc3
|
APN |
16 |
94,268,785 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02898:Ttc3
|
APN |
16 |
94,220,285 (GRCm39) |
missense |
probably damaging |
1.00 |
|
PIT4378001:Ttc3
|
UTSW |
16 |
94,211,765 (GRCm39) |
missense |
probably benign |
0.01 |
|
R0064:Ttc3
|
UTSW |
16 |
94,223,106 (GRCm39) |
missense |
possibly damaging |
0.79 |
|
R0098:Ttc3
|
UTSW |
16 |
94,191,124 (GRCm39) |
missense |
probably benign |
0.02 |
|
R0112:Ttc3
|
UTSW |
16 |
94,186,181 (GRCm39) |
splice site |
probably benign |
|
|
R0480:Ttc3
|
UTSW |
16 |
94,232,863 (GRCm39) |
nonsense |
probably null |
|
|
R0513:Ttc3
|
UTSW |
16 |
94,227,071 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0532:Ttc3
|
UTSW |
16 |
94,188,189 (GRCm39) |
splice site |
probably benign |
|
|
R0607:Ttc3
|
UTSW |
16 |
94,257,644 (GRCm39) |
nonsense |
probably null |
|
|
R0742:Ttc3
|
UTSW |
16 |
94,260,739 (GRCm39) |
missense |
probably benign |
0.23 |
|
R0905:Ttc3
|
UTSW |
16 |
94,257,648 (GRCm39) |
nonsense |
probably null |
|
|
R1118:Ttc3
|
UTSW |
16 |
94,217,127 (GRCm39) |
splice site |
probably benign |
|
|
R1355:Ttc3
|
UTSW |
16 |
94,219,496 (GRCm39) |
missense |
possibly damaging |
0.46 |
|
R1370:Ttc3
|
UTSW |
16 |
94,219,496 (GRCm39) |
missense |
possibly damaging |
0.46 |
|
R1486:Ttc3
|
UTSW |
16 |
94,248,988 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1598:Ttc3
|
UTSW |
16 |
94,223,156 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1641:Ttc3
|
UTSW |
16 |
94,244,176 (GRCm39) |
missense |
probably benign |
0.19 |
|
R2092:Ttc3
|
UTSW |
16 |
94,243,691 (GRCm39) |
missense |
probably benign |
0.02 |
|
R2232:Ttc3
|
UTSW |
16 |
94,260,831 (GRCm39) |
missense |
probably benign |
0.00 |
|
R2339:Ttc3
|
UTSW |
16 |
94,232,857 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2342:Ttc3
|
UTSW |
16 |
94,232,857 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2842:Ttc3
|
UTSW |
16 |
94,232,857 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3117:Ttc3
|
UTSW |
16 |
94,243,422 (GRCm39) |
missense |
possibly damaging |
0.51 |
|
R4194:Ttc3
|
UTSW |
16 |
94,223,136 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4329:Ttc3
|
UTSW |
16 |
94,267,820 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4431:Ttc3
|
UTSW |
16 |
94,211,817 (GRCm39) |
critical splice donor site |
probably null |
|
|
R4530:Ttc3
|
UTSW |
16 |
94,267,736 (GRCm39) |
intron |
probably benign |
|
|
R4531:Ttc3
|
UTSW |
16 |
94,267,736 (GRCm39) |
intron |
probably benign |
|
|
R4532:Ttc3
|
UTSW |
16 |
94,267,736 (GRCm39) |
intron |
probably benign |
|
|
R4533:Ttc3
|
UTSW |
16 |
94,267,736 (GRCm39) |
intron |
probably benign |
|
|
R4588:Ttc3
|
UTSW |
16 |
94,243,760 (GRCm39) |
missense |
probably benign |
0.01 |
|
R4625:Ttc3
|
UTSW |
16 |
94,189,131 (GRCm39) |
nonsense |
probably null |
|
|
R4676:Ttc3
|
UTSW |
16 |
94,243,620 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4700:Ttc3
|
UTSW |
16 |
94,240,100 (GRCm39) |
splice site |
probably null |
|
|
R4856:Ttc3
|
UTSW |
16 |
94,191,142 (GRCm39) |
missense |
probably benign |
0.32 |
|
R4867:Ttc3
|
UTSW |
16 |
94,255,374 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R4885:Ttc3
|
UTSW |
16 |
94,220,324 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4885:Ttc3
|
UTSW |
16 |
94,227,690 (GRCm39) |
critical splice donor site |
probably null |
|
|
R4899:Ttc3
|
UTSW |
16 |
94,230,314 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4997:Ttc3
|
UTSW |
16 |
94,253,841 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5023:Ttc3
|
UTSW |
16 |
94,230,218 (GRCm39) |
missense |
probably benign |
0.01 |
|
R5105:Ttc3
|
UTSW |
16 |
94,267,793 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R5205:Ttc3
|
UTSW |
16 |
94,248,918 (GRCm39) |
missense |
probably benign |
0.07 |
|
R5287:Ttc3
|
UTSW |
16 |
94,260,703 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5338:Ttc3
|
UTSW |
16 |
94,184,900 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5347:Ttc3
|
UTSW |
16 |
94,230,479 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5403:Ttc3
|
UTSW |
16 |
94,260,703 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5460:Ttc3
|
UTSW |
16 |
94,258,241 (GRCm39) |
missense |
probably benign |
0.32 |
|
R5739:Ttc3
|
UTSW |
16 |
94,240,183 (GRCm39) |
nonsense |
probably null |
|
|
R6242:Ttc3
|
UTSW |
16 |
94,243,554 (GRCm39) |
missense |
probably benign |
0.04 |
|
R6253:Ttc3
|
UTSW |
16 |
94,258,272 (GRCm39) |
critical splice donor site |
probably null |
|
|
R6455:Ttc3
|
UTSW |
16 |
94,219,482 (GRCm39) |
start codon destroyed |
probably null |
0.83 |
|
R6559:Ttc3
|
UTSW |
16 |
94,223,208 (GRCm39) |
critical splice donor site |
probably null |
|
|
R6564:Ttc3
|
UTSW |
16 |
94,243,470 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6932:Ttc3
|
UTSW |
16 |
94,244,312 (GRCm39) |
missense |
probably benign |
|
|
R7331:Ttc3
|
UTSW |
16 |
94,195,218 (GRCm39) |
missense |
probably benign |
0.27 |
|
R7497:Ttc3
|
UTSW |
16 |
94,219,541 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R7610:Ttc3
|
UTSW |
16 |
94,228,697 (GRCm39) |
missense |
probably benign |
0.11 |
|
R7738:Ttc3
|
UTSW |
16 |
94,188,241 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7970:Ttc3
|
UTSW |
16 |
94,258,223 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8052:Ttc3
|
UTSW |
16 |
94,268,848 (GRCm39) |
missense |
probably benign |
0.09 |
|
R8087:Ttc3
|
UTSW |
16 |
94,243,812 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8309:Ttc3
|
UTSW |
16 |
94,267,838 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8320:Ttc3
|
UTSW |
16 |
94,219,535 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8322:Ttc3
|
UTSW |
16 |
94,255,351 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8518:Ttc3
|
UTSW |
16 |
94,258,238 (GRCm39) |
missense |
probably benign |
0.21 |
|
R8670:Ttc3
|
UTSW |
16 |
94,191,067 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8826:Ttc3
|
UTSW |
16 |
94,232,829 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R8868:Ttc3
|
UTSW |
16 |
94,252,002 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8873:Ttc3
|
UTSW |
16 |
94,243,842 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R8940:Ttc3
|
UTSW |
16 |
94,230,358 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R8993:Ttc3
|
UTSW |
16 |
94,228,667 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R9068:Ttc3
|
UTSW |
16 |
94,204,219 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9119:Ttc3
|
UTSW |
16 |
94,192,950 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R9124:Ttc3
|
UTSW |
16 |
94,236,389 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9129:Ttc3
|
UTSW |
16 |
94,185,208 (GRCm39) |
missense |
probably benign |
0.02 |
|
R9189:Ttc3
|
UTSW |
16 |
94,268,831 (GRCm39) |
missense |
possibly damaging |
0.62 |
|
R9217:Ttc3
|
UTSW |
16 |
94,230,467 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
R9490:Ttc3
|
UTSW |
16 |
94,245,360 (GRCm39) |
missense |
probably benign |
|
|
R9564:Ttc3
|
UTSW |
16 |
94,248,918 (GRCm39) |
missense |
probably benign |
0.07 |
|
R9631:Ttc3
|
UTSW |
16 |
94,171,581 (GRCm39) |
intron |
probably benign |
|
|
X0022:Ttc3
|
UTSW |
16 |
94,243,384 (GRCm39) |
missense |
probably benign |
0.00 |
|
Y5378:Ttc3
|
UTSW |
16 |
94,212,988 (GRCm39) |
splice site |
probably null |
|
|
| Predicted Primers |
PCR Primer
(F):5'- TGCTGAAATTCTGCTACCCACAAGG -3'
(R):5'- TCCCATCAAAGAGGAAAACGAGCTG -3'
Sequencing Primer
(F):5'- CCCACAAGGGAAGAGTTATTTTACC -3'
(R):5'- TCTAGCTGATGGTCCAGCAG -3'
|
| Posted On |
2013-04-12 |
Incidental Mutation