Incidental Mutation 'R1968:Mon2'
| ID |
219257 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Mon2
|
| Ensembl Gene |
ENSMUSG00000034602 |
| Gene Name |
MON2 homolog, regulator of endosome to Golgi trafficking |
| Synonyms |
2610528O22Rik, SF21 |
| MMRRC Submission |
039981-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably essential
(E-score: 0.898)
|
| Stock # |
R1968 (G1)
|
| Quality Score |
225 |
|
Status
|
Not validated
|
| Chromosome |
10 |
| Chromosomal Location |
122827965-122912410 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to G
at 122845470 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Tyrosine to Histidine
at position 1413
(Y1413H)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000131052
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000037557]
[ENSMUST00000073792]
[ENSMUST00000170935]
|
| AlphaFold |
Q80TL7 |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000037557
AA Change: Y1412H
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000037568
Gene: ENSMUSG00000034602
AA Change: Y1412H
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
119 |
138 |
N/A |
INTRINSIC |
|
low complexity region
|
164 |
176 |
N/A |
INTRINSIC |
|
Pfam:Sec7_N
|
208 |
294 |
6.5e-16 |
PFAM |
|
Pfam:Sec7_N
|
299 |
385 |
2.6e-16 |
PFAM |
|
low complexity region
|
405 |
438 |
N/A |
INTRINSIC |
|
low complexity region
|
558 |
575 |
N/A |
INTRINSIC |
|
low complexity region
|
615 |
627 |
N/A |
INTRINSIC |
|
Pfam:DUF1981
|
844 |
929 |
2.4e-21 |
PFAM |
|
low complexity region
|
984 |
1001 |
N/A |
INTRINSIC |
|
low complexity region
|
1182 |
1193 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000073792
AA Change: Y1419H
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000073462
Gene: ENSMUSG00000034602
AA Change: Y1419H
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:DCB
|
8 |
184 |
3e-72 |
PFAM |
|
Pfam:Sec7_N
|
211 |
384 |
3.1e-58 |
PFAM |
|
low complexity region
|
405 |
438 |
N/A |
INTRINSIC |
|
low complexity region
|
558 |
575 |
N/A |
INTRINSIC |
|
low complexity region
|
615 |
627 |
N/A |
INTRINSIC |
|
Pfam:DUF1981
|
848 |
929 |
6.6e-20 |
PFAM |
|
Pfam:Mon2_C
|
932 |
1706 |
N/A |
PFAM |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000170935
AA Change: Y1413H
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000131052
Gene: ENSMUSG00000034602
AA Change: Y1413H
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
119 |
138 |
N/A |
INTRINSIC |
|
low complexity region
|
164 |
176 |
N/A |
INTRINSIC |
|
Pfam:Sec7_N
|
208 |
294 |
6.5e-16 |
PFAM |
|
Pfam:Sec7_N
|
299 |
385 |
2.6e-16 |
PFAM |
|
low complexity region
|
405 |
438 |
N/A |
INTRINSIC |
|
low complexity region
|
559 |
576 |
N/A |
INTRINSIC |
|
low complexity region
|
616 |
628 |
N/A |
INTRINSIC |
|
Pfam:DUF1981
|
845 |
930 |
8.1e-22 |
PFAM |
|
low complexity region
|
985 |
1002 |
N/A |
INTRINSIC |
|
low complexity region
|
1183 |
1194 |
N/A |
INTRINSIC |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000218735
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000219241
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000222536
|
| Coding Region Coverage |
- 1x: 99.2%
- 3x: 98.5%
- 10x: 96.8%
- 20x: 94.2%
|
| Validation Efficiency |
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 95 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Aadacl4fm4 |
A |
G |
4: 144,397,193 (GRCm39) |
Y180H |
possibly damaging |
Het |
| Abcc10 |
A |
T |
17: 46,633,125 (GRCm39) |
L528Q |
probably damaging |
Het |
| Adam18 |
T |
A |
8: 25,136,463 (GRCm39) |
T353S |
probably benign |
Het |
| Aldh1a3 |
A |
G |
7: 66,061,248 (GRCm39) |
|
probably null |
Het |
| Aldh3b2 |
T |
A |
19: 4,030,705 (GRCm39) |
M390K |
probably benign |
Het |
| Arhgap45 |
T |
C |
10: 79,863,536 (GRCm39) |
I793T |
probably damaging |
Het |
| Arsb |
A |
G |
13: 93,944,067 (GRCm39) |
M253V |
probably benign |
Het |
| Atcay |
T |
C |
10: 81,048,312 (GRCm39) |
D258G |
possibly damaging |
Het |
| Atf1 |
G |
T |
15: 100,152,395 (GRCm39) |
|
probably null |
Het |
| Atp1a4 |
C |
T |
1: 172,067,731 (GRCm39) |
E511K |
probably benign |
Het |
| Atp8a1 |
A |
G |
5: 67,825,000 (GRCm39) |
V777A |
probably benign |
Het |
| Baz1a |
T |
C |
12: 54,947,122 (GRCm39) |
T1173A |
possibly damaging |
Het |
| Bdh2 |
A |
T |
3: 134,991,370 (GRCm39) |
D15V |
probably benign |
Het |
| Cacna1e |
T |
C |
1: 154,576,240 (GRCm39) |
Y69C |
probably damaging |
Het |
| Caskin2 |
A |
G |
11: 115,694,440 (GRCm39) |
L387P |
probably benign |
Het |
| Cat |
T |
C |
2: 103,315,334 (GRCm39) |
E17G |
probably benign |
Het |
| Ccdc15 |
T |
C |
9: 37,259,091 (GRCm39) |
I54M |
probably benign |
Het |
| Ccn1 |
T |
C |
3: 145,353,965 (GRCm39) |
Y275C |
probably damaging |
Het |
| Cdhr1 |
T |
G |
14: 36,801,682 (GRCm39) |
I754L |
probably benign |
Het |
| Cep120 |
G |
A |
18: 53,856,313 (GRCm39) |
T368I |
probably benign |
Het |
| Cep126 |
C |
A |
9: 8,100,909 (GRCm39) |
D542Y |
probably damaging |
Het |
| Cep135 |
T |
C |
5: 76,772,594 (GRCm39) |
S660P |
possibly damaging |
Het |
| Cfap70 |
A |
T |
14: 20,470,879 (GRCm39) |
S455R |
possibly damaging |
Het |
| Chd8 |
A |
G |
14: 52,458,450 (GRCm39) |
M886T |
probably damaging |
Het |
| Ckap5 |
T |
C |
2: 91,416,688 (GRCm39) |
S1098P |
probably benign |
Het |
| Clec4e |
A |
T |
6: 123,260,533 (GRCm39) |
I204N |
probably damaging |
Het |
| Cntnap5c |
G |
A |
17: 58,666,291 (GRCm39) |
R1107H |
probably damaging |
Het |
| Cramp1 |
T |
C |
17: 25,183,913 (GRCm39) |
D1234G |
probably damaging |
Het |
| Csf1r |
A |
T |
18: 61,245,867 (GRCm39) |
I275L |
probably benign |
Het |
| Cyp27a1 |
A |
G |
1: 74,776,435 (GRCm39) |
E457G |
probably benign |
Het |
| Cyp2d11 |
T |
C |
15: 82,273,749 (GRCm39) |
T410A |
probably benign |
Het |
| Cyp2d22 |
G |
C |
15: 82,257,373 (GRCm39) |
T264S |
probably benign |
Het |
| Daam2 |
G |
A |
17: 49,790,088 (GRCm39) |
R390W |
probably damaging |
Het |
| Decr2 |
T |
C |
17: 26,302,053 (GRCm39) |
S226G |
probably benign |
Het |
| Dennd6b |
T |
C |
15: 89,074,544 (GRCm39) |
D91G |
possibly damaging |
Het |
| Dglucy |
T |
C |
12: 100,825,903 (GRCm39) |
V515A |
possibly damaging |
Het |
| Dlg5 |
A |
T |
14: 24,214,187 (GRCm39) |
L734* |
probably null |
Het |
| Dop1b |
A |
G |
16: 93,579,307 (GRCm39) |
N1690D |
probably damaging |
Het |
| Exoc5 |
A |
G |
14: 49,272,347 (GRCm39) |
Y356H |
probably benign |
Het |
| Fut7 |
T |
A |
2: 25,315,738 (GRCm39) |
V332D |
probably benign |
Het |
| Gnas |
T |
C |
2: 174,140,526 (GRCm39) |
S232P |
probably damaging |
Het |
| Gramd4 |
A |
G |
15: 86,017,106 (GRCm39) |
E522G |
probably damaging |
Het |
| Gys1 |
A |
G |
7: 45,092,970 (GRCm39) |
T297A |
probably damaging |
Het |
| Herc4 |
T |
C |
10: 63,109,304 (GRCm39) |
S180P |
probably benign |
Het |
| Hivep3 |
C |
T |
4: 119,953,435 (GRCm39) |
P584S |
possibly damaging |
Het |
| Irag2 |
T |
A |
6: 145,115,499 (GRCm39) |
S310T |
probably damaging |
Het |
| Itpk1 |
G |
T |
12: 102,641,729 (GRCm39) |
|
probably null |
Het |
| Jmjd1c |
A |
T |
10: 67,061,219 (GRCm39) |
S1191C |
probably damaging |
Het |
| Lima1 |
T |
C |
15: 99,717,565 (GRCm39) |
N147S |
probably benign |
Het |
| Map4k5 |
G |
A |
12: 69,865,266 (GRCm39) |
T506I |
probably damaging |
Het |
| Mat1a |
A |
T |
14: 40,832,991 (GRCm39) |
E58V |
probably damaging |
Het |
| Mfsd13a |
T |
C |
19: 46,360,492 (GRCm39) |
L348P |
probably damaging |
Het |
| Mpp3 |
C |
A |
11: 101,909,378 (GRCm39) |
|
probably benign |
Het |
| Mpp4 |
T |
A |
1: 59,183,961 (GRCm39) |
I260F |
probably damaging |
Het |
| Myocd |
C |
A |
11: 65,091,733 (GRCm39) |
G70C |
probably damaging |
Het |
| Nckap1 |
C |
T |
2: 80,348,286 (GRCm39) |
S889N |
probably benign |
Het |
| Nckap5 |
T |
A |
1: 125,942,367 (GRCm39) |
D209V |
probably damaging |
Het |
| Nlrp9a |
A |
G |
7: 26,264,366 (GRCm39) |
K707R |
probably benign |
Het |
| Npr3 |
A |
G |
15: 11,905,055 (GRCm39) |
L224S |
probably benign |
Het |
| Or5m9b |
T |
A |
2: 85,905,549 (GRCm39) |
L155Q |
probably damaging |
Het |
| Or5w20 |
T |
A |
2: 87,727,383 (GRCm39) |
V280E |
probably damaging |
Het |
| Or6c74 |
A |
G |
10: 129,869,602 (GRCm39) |
S36G |
probably damaging |
Het |
| Otof |
C |
T |
5: 30,545,998 (GRCm39) |
D467N |
probably damaging |
Het |
| Paxx |
T |
C |
2: 25,350,640 (GRCm39) |
|
probably benign |
Het |
| Pcmt1 |
G |
A |
10: 7,516,474 (GRCm39) |
R179* |
probably null |
Het |
| Phkb |
T |
A |
8: 86,697,580 (GRCm39) |
V463D |
probably benign |
Het |
| Prkcq |
T |
C |
2: 11,250,208 (GRCm39) |
V175A |
probably damaging |
Het |
| Rasl11b |
T |
G |
5: 74,356,797 (GRCm39) |
I58S |
probably damaging |
Het |
| Rb1cc1 |
A |
T |
1: 6,318,419 (GRCm39) |
|
probably null |
Het |
| Reck |
T |
A |
4: 43,913,771 (GRCm39) |
|
probably null |
Het |
| Riox1 |
G |
T |
12: 83,998,156 (GRCm39) |
D231Y |
probably damaging |
Het |
| Rlf |
T |
A |
4: 121,005,617 (GRCm39) |
N1231I |
probably damaging |
Het |
| Rpn1 |
A |
G |
6: 88,072,530 (GRCm39) |
D291G |
possibly damaging |
Het |
| Samsn1 |
C |
T |
16: 75,742,461 (GRCm39) |
|
noncoding transcript |
Het |
| Scara5 |
T |
C |
14: 65,927,249 (GRCm39) |
C49R |
possibly damaging |
Het |
| Serpini1 |
A |
G |
3: 75,521,785 (GRCm39) |
D92G |
probably benign |
Het |
| Setdb2 |
A |
T |
14: 59,656,858 (GRCm39) |
L153Q |
probably damaging |
Het |
| Sh3rf3 |
C |
T |
10: 58,649,809 (GRCm39) |
T138M |
probably benign |
Het |
| Shkbp1 |
C |
T |
7: 27,054,825 (GRCm39) |
|
probably null |
Het |
| Slc22a29 |
G |
A |
19: 8,195,707 (GRCm39) |
P111S |
probably benign |
Het |
| Smarca1 |
A |
G |
X: 46,941,564 (GRCm39) |
V618A |
probably damaging |
Het |
| Spef2 |
T |
A |
15: 9,609,602 (GRCm39) |
M1308L |
probably damaging |
Het |
| Spink5 |
A |
G |
18: 44,123,775 (GRCm39) |
N354S |
probably benign |
Het |
| Srrm2 |
T |
C |
17: 24,040,465 (GRCm39) |
S2370P |
probably damaging |
Het |
| Ssxb3 |
A |
T |
X: 8,454,905 (GRCm39) |
I28N |
probably damaging |
Het |
| Sucla2 |
A |
G |
14: 73,831,119 (GRCm39) |
T411A |
probably damaging |
Het |
| Tex38 |
A |
C |
4: 115,637,537 (GRCm39) |
S89A |
probably benign |
Het |
| Tjp2 |
A |
T |
19: 24,088,437 (GRCm39) |
D723E |
probably damaging |
Het |
| Tln2 |
A |
T |
9: 67,163,183 (GRCm39) |
N1121K |
probably damaging |
Het |
| Tti1 |
T |
C |
2: 157,850,966 (GRCm39) |
E91G |
possibly damaging |
Het |
| Wbp2 |
A |
T |
11: 115,973,191 (GRCm39) |
M72K |
possibly damaging |
Het |
| Wdfy4 |
C |
A |
14: 32,828,001 (GRCm39) |
C1062F |
possibly damaging |
Het |
| Wiz |
A |
G |
17: 32,578,346 (GRCm39) |
Y389H |
probably damaging |
Het |
| Zcchc3 |
T |
C |
2: 152,256,012 (GRCm39) |
K229R |
probably damaging |
Het |
| Zmat3 |
C |
A |
3: 32,415,131 (GRCm39) |
D60Y |
probably damaging |
Het |
|
| Other mutations in Mon2 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00497:Mon2
|
APN |
10 |
122,862,204 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01072:Mon2
|
APN |
10 |
122,846,444 (GRCm39) |
nonsense |
probably null |
|
|
IGL02080:Mon2
|
APN |
10 |
122,888,095 (GRCm39) |
missense |
probably damaging |
0.98 |
|
IGL02157:Mon2
|
APN |
10 |
122,849,377 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02419:Mon2
|
APN |
10 |
122,852,352 (GRCm39) |
missense |
probably benign |
0.05 |
|
IGL02498:Mon2
|
APN |
10 |
122,870,235 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL02638:Mon2
|
APN |
10 |
122,859,844 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02664:Mon2
|
APN |
10 |
122,845,401 (GRCm39) |
splice site |
probably benign |
|
|
IGL02690:Mon2
|
APN |
10 |
122,845,532 (GRCm39) |
missense |
possibly damaging |
0.67 |
|
IGL02878:Mon2
|
APN |
10 |
122,842,896 (GRCm39) |
missense |
probably benign |
0.09 |
|
IGL03092:Mon2
|
APN |
10 |
122,854,005 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03103:Mon2
|
APN |
10 |
122,866,008 (GRCm39) |
splice site |
probably benign |
|
|
IGL03208:Mon2
|
APN |
10 |
122,853,974 (GRCm39) |
splice site |
probably benign |
|
|
R0010:Mon2
|
UTSW |
10 |
122,868,599 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0016:Mon2
|
UTSW |
10 |
122,871,451 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R0016:Mon2
|
UTSW |
10 |
122,871,451 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R0027:Mon2
|
UTSW |
10 |
122,871,953 (GRCm39) |
missense |
possibly damaging |
0.66 |
|
R0027:Mon2
|
UTSW |
10 |
122,871,953 (GRCm39) |
missense |
possibly damaging |
0.66 |
|
R0145:Mon2
|
UTSW |
10 |
122,849,417 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R0390:Mon2
|
UTSW |
10 |
122,842,926 (GRCm39) |
missense |
probably null |
0.05 |
|
R0481:Mon2
|
UTSW |
10 |
122,849,301 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R0513:Mon2
|
UTSW |
10 |
122,874,515 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0599:Mon2
|
UTSW |
10 |
122,861,970 (GRCm39) |
splice site |
probably benign |
|
|
R1226:Mon2
|
UTSW |
10 |
122,838,724 (GRCm39) |
missense |
probably benign |
0.17 |
|
R1548:Mon2
|
UTSW |
10 |
122,871,912 (GRCm39) |
splice site |
probably benign |
|
|
R1598:Mon2
|
UTSW |
10 |
122,852,301 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1650:Mon2
|
UTSW |
10 |
122,831,682 (GRCm39) |
missense |
probably benign |
0.45 |
|
R1687:Mon2
|
UTSW |
10 |
122,862,029 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R1721:Mon2
|
UTSW |
10 |
122,867,002 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R1768:Mon2
|
UTSW |
10 |
122,849,668 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1827:Mon2
|
UTSW |
10 |
122,882,216 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R1879:Mon2
|
UTSW |
10 |
122,838,790 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1954:Mon2
|
UTSW |
10 |
122,874,388 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1955:Mon2
|
UTSW |
10 |
122,874,388 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2060:Mon2
|
UTSW |
10 |
122,831,681 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2160:Mon2
|
UTSW |
10 |
122,911,834 (GRCm39) |
nonsense |
probably null |
|
|
R2165:Mon2
|
UTSW |
10 |
122,878,269 (GRCm39) |
splice site |
probably null |
|
|
R3737:Mon2
|
UTSW |
10 |
122,849,280 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3814:Mon2
|
UTSW |
10 |
122,849,470 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R4058:Mon2
|
UTSW |
10 |
122,838,724 (GRCm39) |
missense |
probably benign |
0.17 |
|
R4091:Mon2
|
UTSW |
10 |
122,874,415 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4214:Mon2
|
UTSW |
10 |
122,852,397 (GRCm39) |
missense |
probably benign |
0.03 |
|
R4354:Mon2
|
UTSW |
10 |
122,862,888 (GRCm39) |
missense |
probably benign |
0.02 |
|
R4422:Mon2
|
UTSW |
10 |
122,878,887 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4505:Mon2
|
UTSW |
10 |
122,845,494 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4791:Mon2
|
UTSW |
10 |
122,841,962 (GRCm39) |
missense |
probably benign |
0.01 |
|
R4797:Mon2
|
UTSW |
10 |
122,852,422 (GRCm39) |
missense |
probably benign |
0.45 |
|
R4944:Mon2
|
UTSW |
10 |
122,874,364 (GRCm39) |
critical splice donor site |
probably null |
|
|
R4982:Mon2
|
UTSW |
10 |
122,831,694 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5298:Mon2
|
UTSW |
10 |
122,846,511 (GRCm39) |
missense |
probably benign |
|
|
R5503:Mon2
|
UTSW |
10 |
122,868,550 (GRCm39) |
missense |
possibly damaging |
0.54 |
|
R5653:Mon2
|
UTSW |
10 |
122,861,999 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R5687:Mon2
|
UTSW |
10 |
122,844,144 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5838:Mon2
|
UTSW |
10 |
122,846,397 (GRCm39) |
critical splice donor site |
probably null |
|
|
R6108:Mon2
|
UTSW |
10 |
122,868,600 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6182:Mon2
|
UTSW |
10 |
122,874,564 (GRCm39) |
splice site |
probably null |
|
|
R6355:Mon2
|
UTSW |
10 |
122,858,825 (GRCm39) |
missense |
possibly damaging |
0.58 |
|
R6358:Mon2
|
UTSW |
10 |
122,849,409 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R6548:Mon2
|
UTSW |
10 |
122,871,998 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6557:Mon2
|
UTSW |
10 |
122,852,307 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6649:Mon2
|
UTSW |
10 |
122,874,385 (GRCm39) |
missense |
possibly damaging |
0.46 |
|
R7140:Mon2
|
UTSW |
10 |
122,871,358 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7303:Mon2
|
UTSW |
10 |
122,874,364 (GRCm39) |
critical splice donor site |
probably null |
|
|
R7317:Mon2
|
UTSW |
10 |
122,849,851 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R7355:Mon2
|
UTSW |
10 |
122,845,421 (GRCm39) |
missense |
probably benign |
|
|
R7508:Mon2
|
UTSW |
10 |
122,859,844 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7509:Mon2
|
UTSW |
10 |
122,868,457 (GRCm39) |
missense |
probably benign |
|
|
R7647:Mon2
|
UTSW |
10 |
122,841,931 (GRCm39) |
missense |
probably benign |
|
|
R7720:Mon2
|
UTSW |
10 |
122,868,493 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7799:Mon2
|
UTSW |
10 |
122,878,236 (GRCm39) |
missense |
probably benign |
0.41 |
|
R7801:Mon2
|
UTSW |
10 |
122,895,091 (GRCm39) |
critical splice donor site |
probably null |
|
|
R7823:Mon2
|
UTSW |
10 |
122,868,559 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7985:Mon2
|
UTSW |
10 |
122,852,213 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8310:Mon2
|
UTSW |
10 |
122,838,688 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8810:Mon2
|
UTSW |
10 |
122,845,516 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R8825:Mon2
|
UTSW |
10 |
122,849,776 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8937:Mon2
|
UTSW |
10 |
122,895,110 (GRCm39) |
missense |
probably benign |
|
|
R8978:Mon2
|
UTSW |
10 |
122,871,469 (GRCm39) |
nonsense |
probably null |
|
|
R9011:Mon2
|
UTSW |
10 |
122,862,213 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R9213:Mon2
|
UTSW |
10 |
122,872,016 (GRCm39) |
nonsense |
probably null |
|
|
R9358:Mon2
|
UTSW |
10 |
122,868,452 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9630:Mon2
|
UTSW |
10 |
122,874,415 (GRCm39) |
missense |
probably damaging |
1.00 |
|
X0022:Mon2
|
UTSW |
10 |
122,842,007 (GRCm39) |
missense |
probably benign |
0.07 |
|
| Predicted Primers |
PCR Primer
(F):5'- GCCCTACTACTGAAGTACCCTC -3'
(R):5'- ACCAAGGCCTGAACTTGTAAGG -3'
Sequencing Primer
(F):5'- TGCTTGCCAAATACAATCCATG -3'
(R):5'- TGAACTTGTAAGGAAAAAGAGCTTCC -3'
|
| Posted On |
2014-08-25 |
Incidental Mutation