Incidental Mutation 'R1986:Psme4'
| ID |
220689 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Psme4
|
| Ensembl Gene |
ENSMUSG00000040850 |
| Gene Name |
proteasome (prosome, macropain) activator subunit 4 |
| Synonyms |
|
| MMRRC Submission |
039998-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R1986 (G1)
|
| Quality Score |
225 |
|
Status
|
Not validated
|
| Chromosome |
11 |
| Chromosomal Location |
30721726-30830361 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to C
at 30780352 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Valine to Alanine
at position 840
(V840A)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000045460
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000041231]
|
| AlphaFold |
Q5SSW2 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000041231
AA Change: V840A
PolyPhen 2
Score 0.012 (Sensitivity: 0.96; Specificity: 0.78)
|
| SMART Domains |
Protein: ENSMUSP00000045460
Gene: ENSMUSG00000040850
AA Change: V840A
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
2 |
19 |
N/A |
INTRINSIC |
|
low complexity region
|
122 |
133 |
N/A |
INTRINSIC |
|
Pfam:BLM10_mid
|
330 |
828 |
8.8e-119 |
PFAM |
|
SCOP:d1b3ua_
|
1183 |
1716 |
3e-14 |
SMART |
|
Pfam:DUF3437
|
1756 |
1843 |
5.3e-39 |
PFAM |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000142217
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000150219
|
| Coding Region Coverage |
- 1x: 99.1%
- 3x: 98.4%
- 10x: 96.7%
- 20x: 93.7%
|
| Validation Efficiency |
|
| MGI Phenotype |
PHENOTYPE: Mice homozygous for a knock-out allele show normal repair of DNA double-strand breaks but exhibit significantly reduced male fertility due to defects in spermatogenesis observed in both meiotic spermatocytes and postmeiotic haploid spermatids. [provided by MGI curators]
|
| Allele List at MGI |
All alleles(25) : Targeted, knock-out(1) Gene trapped(24) |
| Other mutations in this stock |
Total: 91 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 1700006A11Rik |
A |
G |
3: 124,212,977 (GRCm39) |
S105P |
probably damaging |
Het |
| 9930111J21Rik2 |
T |
A |
11: 48,910,119 (GRCm39) |
K771N |
possibly damaging |
Het |
| Abcc2 |
A |
G |
19: 43,818,318 (GRCm39) |
E1268G |
probably damaging |
Het |
| Adamts4 |
T |
C |
1: 171,084,244 (GRCm39) |
F574L |
possibly damaging |
Het |
| Adamts9 |
A |
G |
6: 92,773,375 (GRCm39) |
V1165A |
probably benign |
Het |
| Agap2 |
A |
T |
10: 126,918,913 (GRCm39) |
K430* |
probably null |
Het |
| Amn |
G |
T |
12: 111,241,431 (GRCm39) |
G232V |
probably damaging |
Het |
| Ank3 |
A |
G |
10: 69,703,258 (GRCm39) |
E297G |
probably damaging |
Het |
| Arhgap45 |
T |
C |
10: 79,856,530 (GRCm39) |
L26P |
probably damaging |
Het |
| Atp10b |
C |
A |
11: 43,063,595 (GRCm39) |
Q177K |
probably benign |
Het |
| Bbs10 |
A |
T |
10: 111,135,118 (GRCm39) |
D77V |
probably damaging |
Het |
| Bltp2 |
A |
T |
11: 78,165,438 (GRCm39) |
H1318L |
probably damaging |
Het |
| Bpifa1 |
T |
A |
2: 153,986,256 (GRCm39) |
L127Q |
probably damaging |
Het |
| Brinp2 |
T |
C |
1: 158,074,348 (GRCm39) |
N591S |
probably damaging |
Het |
| C2cd2 |
A |
C |
16: 97,671,471 (GRCm39) |
V476G |
probably damaging |
Het |
| C7 |
T |
A |
15: 5,041,494 (GRCm39) |
T471S |
possibly damaging |
Het |
| Cacna1b |
A |
T |
2: 24,538,998 (GRCm39) |
Y1488N |
probably damaging |
Het |
| Cadps2 |
A |
G |
6: 23,323,379 (GRCm39) |
F1001L |
probably damaging |
Het |
| Ccdc188 |
T |
C |
16: 18,036,707 (GRCm39) |
S216P |
probably damaging |
Het |
| Ccdc24 |
A |
G |
4: 117,729,213 (GRCm39) |
L88P |
probably damaging |
Het |
| Dab1 |
T |
C |
4: 104,470,412 (GRCm39) |
I65T |
probably damaging |
Het |
| Dock4 |
A |
T |
12: 40,780,062 (GRCm39) |
D621V |
probably damaging |
Het |
| Drd5 |
A |
T |
5: 38,477,456 (GRCm39) |
M150L |
probably damaging |
Het |
| Eef2k |
T |
A |
7: 120,472,569 (GRCm39) |
M94K |
possibly damaging |
Het |
| Epg5 |
A |
G |
18: 78,025,521 (GRCm39) |
|
probably null |
Het |
| Epsti1 |
T |
C |
14: 78,169,673 (GRCm39) |
|
probably null |
Het |
| Ern2 |
T |
A |
7: 121,770,752 (GRCm39) |
D754V |
probably benign |
Het |
| Fbxo6 |
A |
G |
4: 148,230,552 (GRCm39) |
Y237H |
probably damaging |
Het |
| Fbxw24 |
A |
G |
9: 109,436,124 (GRCm39) |
S303P |
probably damaging |
Het |
| Fpr-rs3 |
A |
T |
17: 20,844,103 (GRCm39) |
|
probably null |
Het |
| Gab1 |
G |
T |
8: 81,493,010 (GRCm39) |
T679K |
probably damaging |
Het |
| Gbp9 |
C |
A |
5: 105,253,590 (GRCm39) |
V42F |
probably damaging |
Het |
| Gbp9 |
A |
T |
5: 105,253,652 (GRCm39) |
V21E |
probably damaging |
Het |
| Gm20821 |
A |
G |
Y: 9,783,927 (GRCm39) |
Q183R |
probably benign |
Het |
| Gpatch11 |
A |
T |
17: 79,151,266 (GRCm39) |
I226F |
probably benign |
Het |
| Hephl1 |
T |
G |
9: 14,965,848 (GRCm39) |
E1035A |
probably damaging |
Het |
| Hspa4l |
T |
C |
3: 40,714,833 (GRCm39) |
V156A |
probably damaging |
Het |
| Ifna13 |
A |
G |
4: 88,562,588 (GRCm39) |
V12A |
probably benign |
Het |
| Il24 |
G |
A |
1: 130,810,268 (GRCm39) |
T196I |
probably benign |
Het |
| Irgm2 |
A |
G |
11: 58,110,384 (GRCm39) |
D37G |
probably benign |
Het |
| Irs1 |
A |
G |
1: 82,266,486 (GRCm39) |
S577P |
probably damaging |
Het |
| Kif21b |
G |
A |
1: 136,075,284 (GRCm39) |
D166N |
probably damaging |
Het |
| Krtap4-16 |
T |
C |
11: 99,742,322 (GRCm39) |
Q26R |
unknown |
Het |
| Lig1 |
T |
A |
7: 13,043,067 (GRCm39) |
Y837* |
probably null |
Het |
| Lrrc69 |
T |
C |
4: 14,708,669 (GRCm39) |
E225G |
possibly damaging |
Het |
| Map3k20 |
C |
T |
2: 72,271,638 (GRCm39) |
Q589* |
probably null |
Het |
| Masp1 |
T |
G |
16: 23,302,211 (GRCm39) |
M347L |
probably benign |
Het |
| Mgat3 |
A |
T |
15: 80,096,390 (GRCm39) |
I406F |
probably benign |
Het |
| Mmp1b |
T |
G |
9: 7,368,577 (GRCm39) |
D425A |
probably benign |
Het |
| Mss51 |
T |
C |
14: 20,533,259 (GRCm39) |
H404R |
probably benign |
Het |
| Myo15b |
A |
T |
11: 115,773,701 (GRCm39) |
H1911L |
probably benign |
Het |
| Nedd4l |
A |
G |
18: 65,276,874 (GRCm39) |
D102G |
probably damaging |
Het |
| Niban3 |
T |
A |
8: 72,056,404 (GRCm39) |
I368N |
possibly damaging |
Het |
| Npc2 |
T |
C |
12: 84,807,523 (GRCm39) |
K112E |
probably benign |
Het |
| Nuggc |
T |
A |
14: 65,879,370 (GRCm39) |
V694E |
probably damaging |
Het |
| Olfm1 |
T |
G |
2: 28,104,718 (GRCm39) |
V157G |
probably benign |
Het |
| Or10h28 |
T |
C |
17: 33,488,489 (GRCm39) |
S264P |
probably benign |
Het |
| Or5p55 |
T |
C |
7: 107,566,877 (GRCm39) |
V91A |
probably benign |
Het |
| Otogl |
T |
A |
10: 107,630,051 (GRCm39) |
|
probably null |
Het |
| Ovgp1 |
G |
A |
3: 105,882,251 (GRCm39) |
C38Y |
probably damaging |
Het |
| Pisd |
A |
T |
5: 32,894,672 (GRCm39) |
S344T |
probably damaging |
Het |
| Ptch1 |
T |
G |
13: 63,672,773 (GRCm39) |
E944A |
probably benign |
Het |
| Rims2 |
T |
A |
15: 39,208,710 (GRCm39) |
M171K |
probably damaging |
Het |
| Rin2 |
T |
A |
2: 145,720,860 (GRCm39) |
M731K |
probably damaging |
Het |
| Scgb1b19 |
T |
C |
7: 32,987,108 (GRCm39) |
|
probably null |
Het |
| Serpina10 |
A |
G |
12: 103,594,514 (GRCm39) |
I235T |
possibly damaging |
Het |
| Setbp1 |
T |
A |
18: 78,901,759 (GRCm39) |
E636V |
probably damaging |
Het |
| Sh3d21 |
C |
T |
4: 126,056,290 (GRCm39) |
E101K |
probably damaging |
Het |
| Ski |
T |
G |
4: 155,306,148 (GRCm39) |
D225A |
probably damaging |
Het |
| Slc28a2b |
A |
G |
2: 122,357,910 (GRCm39) |
T655A |
probably benign |
Het |
| Slc29a3 |
T |
C |
10: 60,559,593 (GRCm39) |
Y187C |
probably damaging |
Het |
| Sort1 |
T |
A |
3: 108,253,043 (GRCm39) |
D494E |
possibly damaging |
Het |
| Sphkap |
A |
T |
1: 83,255,643 (GRCm39) |
L702Q |
probably damaging |
Het |
| Srr |
A |
G |
11: 74,799,545 (GRCm39) |
I285T |
probably damaging |
Het |
| Stam2 |
T |
C |
2: 52,599,638 (GRCm39) |
T257A |
possibly damaging |
Het |
| Suds3 |
A |
T |
5: 117,246,417 (GRCm39) |
N112K |
probably damaging |
Het |
| Tedc2 |
T |
A |
17: 24,435,291 (GRCm39) |
E366V |
probably damaging |
Het |
| Tedc2 |
C |
A |
17: 24,435,292 (GRCm39) |
E366* |
probably null |
Het |
| Tesk2 |
T |
C |
4: 116,608,390 (GRCm39) |
L104P |
probably damaging |
Het |
| Tie1 |
C |
T |
4: 118,336,160 (GRCm39) |
R702H |
probably benign |
Het |
| Tpo |
G |
T |
12: 30,169,465 (GRCm39) |
A90E |
probably damaging |
Het |
| Trim30a |
T |
C |
7: 104,060,672 (GRCm39) |
D368G |
probably damaging |
Het |
| Ugt2a2 |
A |
T |
5: 87,608,438 (GRCm39) |
M633K |
possibly damaging |
Het |
| Vars2 |
A |
G |
17: 35,970,953 (GRCm39) |
W626R |
probably damaging |
Het |
| Vmn2r10 |
A |
T |
5: 109,154,120 (GRCm39) |
Y61* |
probably null |
Het |
| Vmn2r95 |
T |
C |
17: 18,671,805 (GRCm39) |
V514A |
probably benign |
Het |
| Vwa5a |
T |
G |
9: 38,649,110 (GRCm39) |
|
probably benign |
Het |
| Zfp365 |
A |
T |
10: 67,745,686 (GRCm39) |
C31S |
probably damaging |
Het |
| Zfp397 |
A |
T |
18: 24,093,108 (GRCm39) |
I198F |
possibly damaging |
Het |
| Zfp407 |
C |
T |
18: 84,577,898 (GRCm39) |
A1072T |
probably benign |
Het |
| Zfp593 |
T |
C |
4: 133,972,206 (GRCm39) |
E100G |
possibly damaging |
Het |
|
| Other mutations in Psme4 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00228:Psme4
|
APN |
11 |
30,765,710 (GRCm39) |
critical splice donor site |
probably null |
|
|
IGL00401:Psme4
|
APN |
11 |
30,771,079 (GRCm39) |
splice site |
probably benign |
|
|
IGL00475:Psme4
|
APN |
11 |
30,795,252 (GRCm39) |
missense |
probably benign |
0.14 |
|
IGL00576:Psme4
|
APN |
11 |
30,773,145 (GRCm39) |
missense |
possibly damaging |
0.50 |
|
IGL00817:Psme4
|
APN |
11 |
30,770,129 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL01525:Psme4
|
APN |
11 |
30,759,936 (GRCm39) |
splice site |
probably benign |
|
|
IGL01862:Psme4
|
APN |
11 |
30,762,038 (GRCm39) |
nonsense |
probably null |
|
|
IGL02310:Psme4
|
APN |
11 |
30,787,484 (GRCm39) |
missense |
probably benign |
0.06 |
|
IGL02477:Psme4
|
APN |
11 |
30,792,083 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL02545:Psme4
|
APN |
11 |
30,791,586 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
IGL02608:Psme4
|
APN |
11 |
30,770,944 (GRCm39) |
missense |
probably benign |
0.34 |
|
IGL02621:Psme4
|
APN |
11 |
30,798,131 (GRCm39) |
missense |
probably benign |
|
|
IGL02822:Psme4
|
APN |
11 |
30,798,204 (GRCm39) |
unclassified |
probably benign |
|
|
IGL02833:Psme4
|
APN |
11 |
30,800,715 (GRCm39) |
unclassified |
probably benign |
|
|
IGL02964:Psme4
|
APN |
11 |
30,741,095 (GRCm39) |
nonsense |
probably null |
|
|
IGL03273:Psme4
|
APN |
11 |
30,798,130 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03348:Psme4
|
APN |
11 |
30,826,796 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03382:Psme4
|
APN |
11 |
30,757,788 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
H2330:Psme4
|
UTSW |
11 |
30,801,210 (GRCm39) |
missense |
probably benign |
0.17 |
|
PIT4378001:Psme4
|
UTSW |
11 |
30,771,079 (GRCm39) |
splice site |
probably benign |
|
|
R0276:Psme4
|
UTSW |
11 |
30,761,980 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0462:Psme4
|
UTSW |
11 |
30,798,117 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0685:Psme4
|
UTSW |
11 |
30,828,415 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0766:Psme4
|
UTSW |
11 |
30,757,687 (GRCm39) |
splice site |
probably null |
|
|
R0830:Psme4
|
UTSW |
11 |
30,757,797 (GRCm39) |
missense |
possibly damaging |
0.53 |
|
R0940:Psme4
|
UTSW |
11 |
30,765,264 (GRCm39) |
missense |
possibly damaging |
0.53 |
|
R1018:Psme4
|
UTSW |
11 |
30,754,310 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1312:Psme4
|
UTSW |
11 |
30,757,687 (GRCm39) |
splice site |
probably null |
|
|
R1448:Psme4
|
UTSW |
11 |
30,802,744 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1713:Psme4
|
UTSW |
11 |
30,756,310 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1732:Psme4
|
UTSW |
11 |
30,798,105 (GRCm39) |
missense |
probably benign |
0.03 |
|
R1813:Psme4
|
UTSW |
11 |
30,754,353 (GRCm39) |
missense |
probably benign |
0.14 |
|
R1905:Psme4
|
UTSW |
11 |
30,760,922 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1907:Psme4
|
UTSW |
11 |
30,760,922 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1911:Psme4
|
UTSW |
11 |
30,765,658 (GRCm39) |
missense |
probably benign |
0.02 |
|
R1956:Psme4
|
UTSW |
11 |
30,782,424 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1974:Psme4
|
UTSW |
11 |
30,769,011 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1980:Psme4
|
UTSW |
11 |
30,782,615 (GRCm39) |
missense |
possibly damaging |
0.84 |
|
R2046:Psme4
|
UTSW |
11 |
30,767,723 (GRCm39) |
splice site |
probably benign |
|
|
R2142:Psme4
|
UTSW |
11 |
30,770,998 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R2698:Psme4
|
UTSW |
11 |
30,824,282 (GRCm39) |
critical splice donor site |
probably null |
|
|
R2844:Psme4
|
UTSW |
11 |
30,795,173 (GRCm39) |
splice site |
probably benign |
|
|
R3807:Psme4
|
UTSW |
11 |
30,806,027 (GRCm39) |
splice site |
probably null |
|
|
R3876:Psme4
|
UTSW |
11 |
30,806,068 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4420:Psme4
|
UTSW |
11 |
30,762,028 (GRCm39) |
missense |
possibly damaging |
0.67 |
|
R4584:Psme4
|
UTSW |
11 |
30,784,318 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4615:Psme4
|
UTSW |
11 |
30,784,287 (GRCm39) |
missense |
probably benign |
0.02 |
|
R4714:Psme4
|
UTSW |
11 |
30,782,573 (GRCm39) |
missense |
probably benign |
0.02 |
|
R5008:Psme4
|
UTSW |
11 |
30,806,896 (GRCm39) |
intron |
probably benign |
|
|
R5109:Psme4
|
UTSW |
11 |
30,741,095 (GRCm39) |
nonsense |
probably null |
|
|
R5155:Psme4
|
UTSW |
11 |
30,826,806 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5199:Psme4
|
UTSW |
11 |
30,803,272 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5205:Psme4
|
UTSW |
11 |
30,782,666 (GRCm39) |
intron |
probably benign |
|
|
R5452:Psme4
|
UTSW |
11 |
30,741,168 (GRCm39) |
missense |
probably benign |
|
|
R5491:Psme4
|
UTSW |
11 |
30,765,246 (GRCm39) |
missense |
possibly damaging |
0.63 |
|
R5685:Psme4
|
UTSW |
11 |
30,759,837 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5764:Psme4
|
UTSW |
11 |
30,722,364 (GRCm39) |
intron |
probably benign |
|
|
R5853:Psme4
|
UTSW |
11 |
30,741,234 (GRCm39) |
critical splice donor site |
probably null |
|
|
R5865:Psme4
|
UTSW |
11 |
30,741,993 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R5903:Psme4
|
UTSW |
11 |
30,791,589 (GRCm39) |
missense |
probably benign |
0.28 |
|
R5927:Psme4
|
UTSW |
11 |
30,754,294 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
R6004:Psme4
|
UTSW |
11 |
30,806,896 (GRCm39) |
intron |
probably benign |
|
|
R6102:Psme4
|
UTSW |
11 |
30,815,567 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6247:Psme4
|
UTSW |
11 |
30,803,245 (GRCm39) |
missense |
possibly damaging |
0.60 |
|
R6527:Psme4
|
UTSW |
11 |
30,782,175 (GRCm39) |
missense |
probably benign |
|
|
R6750:Psme4
|
UTSW |
11 |
30,803,203 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6885:Psme4
|
UTSW |
11 |
30,784,307 (GRCm39) |
nonsense |
probably null |
|
|
R6939:Psme4
|
UTSW |
11 |
30,787,291 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6945:Psme4
|
UTSW |
11 |
30,787,437 (GRCm39) |
missense |
probably benign |
0.06 |
|
R7029:Psme4
|
UTSW |
11 |
30,722,474 (GRCm39) |
intron |
probably benign |
|
|
R7049:Psme4
|
UTSW |
11 |
30,763,904 (GRCm39) |
splice site |
probably null |
|
|
R7098:Psme4
|
UTSW |
11 |
30,800,661 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7107:Psme4
|
UTSW |
11 |
30,798,105 (GRCm39) |
missense |
probably benign |
0.03 |
|
R7223:Psme4
|
UTSW |
11 |
30,824,226 (GRCm39) |
missense |
probably benign |
0.33 |
|
R7319:Psme4
|
UTSW |
11 |
30,757,790 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7375:Psme4
|
UTSW |
11 |
30,722,700 (GRCm39) |
splice site |
probably null |
|
|
R7410:Psme4
|
UTSW |
11 |
30,765,279 (GRCm39) |
nonsense |
probably null |
|
|
R7469:Psme4
|
UTSW |
11 |
30,752,837 (GRCm39) |
missense |
probably benign |
0.20 |
|
R7651:Psme4
|
UTSW |
11 |
30,787,334 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R7679:Psme4
|
UTSW |
11 |
30,828,425 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7681:Psme4
|
UTSW |
11 |
30,741,975 (GRCm39) |
missense |
possibly damaging |
0.63 |
|
R7822:Psme4
|
UTSW |
11 |
30,824,245 (GRCm39) |
missense |
probably benign |
|
|
R8013:Psme4
|
UTSW |
11 |
30,754,320 (GRCm39) |
missense |
probably benign |
0.06 |
|
R8130:Psme4
|
UTSW |
11 |
30,792,026 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8323:Psme4
|
UTSW |
11 |
30,793,532 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8330:Psme4
|
UTSW |
11 |
30,793,583 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8363:Psme4
|
UTSW |
11 |
30,762,139 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8491:Psme4
|
UTSW |
11 |
30,722,161 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R8690:Psme4
|
UTSW |
11 |
30,787,319 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8696:Psme4
|
UTSW |
11 |
30,759,896 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8743:Psme4
|
UTSW |
11 |
30,828,467 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8998:Psme4
|
UTSW |
11 |
30,788,957 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
R9241:Psme4
|
UTSW |
11 |
30,815,576 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9657:Psme4
|
UTSW |
11 |
30,788,980 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9736:Psme4
|
UTSW |
11 |
30,797,411 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9744:Psme4
|
UTSW |
11 |
30,765,294 (GRCm39) |
critical splice donor site |
probably null |
|
|
R9746:Psme4
|
UTSW |
11 |
30,826,868 (GRCm39) |
nonsense |
probably null |
|
|
V5088:Psme4
|
UTSW |
11 |
30,801,210 (GRCm39) |
missense |
probably benign |
0.17 |
|
X0063:Psme4
|
UTSW |
11 |
30,782,600 (GRCm39) |
missense |
possibly damaging |
0.66 |
|
Z1176:Psme4
|
UTSW |
11 |
30,793,522 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
Z1177:Psme4
|
UTSW |
11 |
30,762,138 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1177:Psme4
|
UTSW |
11 |
30,756,311 (GRCm39) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- TGATACAGCAGCATTAATCTTCAGAAG -3'
(R):5'- TGGACCCAATTTCTATGATTTACTGTC -3'
Sequencing Primer
(F):5'- GACTAGAAATTTGTTACAGGGT -3'
(R):5'- TCTAGAAGCATTAGGCCAGCCTTG -3'
|
| Posted On |
2014-08-25 |
Incidental Mutation