Incidental Mutation 'R2029:Myh13'
| ID |
221024 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Myh13
|
| Ensembl Gene |
ENSMUSG00000060180 |
| Gene Name |
myosin, heavy polypeptide 13, skeletal muscle |
| Synonyms |
EO Myosin, MyHC-eo, extraocular myosin |
| MMRRC Submission |
040036-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.132)
|
| Stock # |
R2029 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
|
| Chromosome |
11 |
| Chromosomal Location |
67217929-67262413 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to T
at 67252115 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Threonine to Serine
at position 1408
(T1408S)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000137731
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000081911]
[ENSMUST00000108684]
[ENSMUST00000180845]
|
| AlphaFold |
B1AR69 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000081911
AA Change: T1408S
PolyPhen 2
Score 0.027 (Sensitivity: 0.95; Specificity: 0.81)
|
| SMART Domains |
Protein: ENSMUSP00000080584
Gene: ENSMUSG00000060180
AA Change: T1408S
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:Myosin_N
|
35 |
74 |
8e-13 |
PFAM |
|
MYSc
|
80 |
783 |
N/A |
SMART |
|
IQ
|
784 |
806 |
4.6e-1 |
SMART |
|
Pfam:Myosin_tail_1
|
847 |
1928 |
4.6e-159 |
PFAM |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000108684
AA Change: T1408S
PolyPhen 2
Score 0.027 (Sensitivity: 0.95; Specificity: 0.81)
|
| SMART Domains |
Protein: ENSMUSP00000104324
Gene: ENSMUSG00000060180
AA Change: T1408S
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:Myosin_N
|
35 |
76 |
2.8e-14 |
PFAM |
|
MYSc
|
80 |
783 |
N/A |
SMART |
|
IQ
|
784 |
806 |
4.6e-1 |
SMART |
|
low complexity region
|
847 |
858 |
N/A |
INTRINSIC |
|
low complexity region
|
925 |
940 |
N/A |
INTRINSIC |
|
Pfam:Myosin_tail_1
|
1072 |
1930 |
N/A |
PFAM |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000122618
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000180845
AA Change: T1408S
PolyPhen 2
Score 0.027 (Sensitivity: 0.95; Specificity: 0.81)
|
| SMART Domains |
Protein: ENSMUSP00000137731
Gene: ENSMUSG00000060180
AA Change: T1408S
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:Myosin_N
|
35 |
76 |
2.8e-14 |
PFAM |
|
MYSc
|
80 |
783 |
N/A |
SMART |
|
IQ
|
784 |
806 |
4.6e-1 |
SMART |
|
low complexity region
|
847 |
858 |
N/A |
INTRINSIC |
|
low complexity region
|
925 |
940 |
N/A |
INTRINSIC |
|
Pfam:Myosin_tail_1
|
1072 |
1930 |
N/A |
PFAM |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000181027
|
| Meta Mutation Damage Score |
0.1722 |
| Coding Region Coverage |
- 1x: 99.2%
- 3x: 98.5%
- 10x: 96.8%
- 20x: 93.8%
|
| Validation Efficiency |
98% (97/99) |
| Allele List at MGI |
All alleles(4) : Gene trapped(4) |
| Other mutations in this stock |
Total: 100 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Adam18 |
C |
G |
8: 25,140,893 (GRCm39) |
G286A |
probably damaging |
Het |
| Adcy1 |
G |
A |
11: 7,089,142 (GRCm39) |
A519T |
probably benign |
Het |
| Anxa2 |
T |
A |
9: 69,371,762 (GRCm39) |
S2T |
possibly damaging |
Het |
| Ap3m1 |
G |
A |
14: 21,089,217 (GRCm39) |
S261L |
possibly damaging |
Het |
| Baz2b |
A |
T |
2: 59,743,067 (GRCm39) |
|
probably benign |
Het |
| Brdt |
T |
A |
5: 107,507,090 (GRCm39) |
S497T |
probably benign |
Het |
| Cdh11 |
A |
G |
8: 103,406,404 (GRCm39) |
F23S |
probably benign |
Het |
| Cdh16 |
A |
C |
8: 105,344,434 (GRCm39) |
L540R |
probably damaging |
Het |
| Ces5a |
A |
T |
8: 94,261,205 (GRCm39) |
L74Q |
probably damaging |
Het |
| Cfap69 |
A |
G |
5: 5,654,306 (GRCm39) |
S543P |
probably damaging |
Het |
| Cfap74 |
T |
C |
4: 155,526,538 (GRCm39) |
I763T |
possibly damaging |
Het |
| Cma1 |
T |
A |
14: 56,181,191 (GRCm39) |
R58S |
possibly damaging |
Het |
| Csmd3 |
C |
T |
15: 47,701,975 (GRCm39) |
D1599N |
probably damaging |
Het |
| Cyld |
A |
G |
8: 89,471,940 (GRCm39) |
K857R |
probably benign |
Het |
| Cyp3a16 |
T |
C |
5: 145,388,667 (GRCm39) |
D270G |
probably damaging |
Het |
| D1Pas1 |
T |
C |
1: 186,700,286 (GRCm39) |
S72P |
possibly damaging |
Het |
| Ddx3y |
T |
C |
Y: 1,266,389 (GRCm39) |
E331G |
probably benign |
Het |
| Degs1l |
T |
A |
1: 180,882,496 (GRCm39) |
I86K |
probably benign |
Het |
| Dis3l2 |
T |
C |
1: 86,782,189 (GRCm39) |
|
probably benign |
Het |
| Dop1a |
G |
T |
9: 86,403,418 (GRCm39) |
W1539C |
probably damaging |
Het |
| Dop1b |
A |
G |
16: 93,566,323 (GRCm39) |
K917E |
probably benign |
Het |
| Ecpas |
G |
A |
4: 58,844,165 (GRCm39) |
R534* |
probably null |
Het |
| Efcab3 |
T |
C |
11: 104,990,851 (GRCm39) |
I5462T |
probably damaging |
Het |
| Eif1ad15 |
A |
T |
12: 88,288,191 (GRCm39) |
S21T |
unknown |
Het |
| Epo |
A |
G |
5: 137,483,447 (GRCm39) |
|
probably benign |
Het |
| Figla |
T |
A |
6: 85,997,624 (GRCm39) |
|
probably benign |
Het |
| Flvcr1 |
T |
C |
1: 190,753,353 (GRCm39) |
D273G |
probably benign |
Het |
| Fryl |
T |
A |
5: 73,179,465 (GRCm39) |
R304* |
probably null |
Het |
| Gcm1 |
T |
G |
9: 77,972,326 (GRCm39) |
D422E |
possibly damaging |
Het |
| Get3 |
A |
T |
8: 85,746,403 (GRCm39) |
Y148* |
probably null |
Het |
| Ggt6 |
A |
G |
11: 72,328,367 (GRCm39) |
D251G |
possibly damaging |
Het |
| Git2 |
A |
G |
5: 114,904,511 (GRCm39) |
|
probably null |
Het |
| Gm18856 |
A |
T |
13: 14,139,376 (GRCm39) |
|
probably benign |
Het |
| Gm20939 |
T |
A |
17: 95,183,252 (GRCm39) |
|
probably benign |
Het |
| Gpr176 |
A |
G |
2: 118,109,913 (GRCm39) |
Y449H |
probably benign |
Het |
| H2-Eb1 |
A |
G |
17: 34,533,366 (GRCm39) |
E196G |
probably damaging |
Het |
| H2-M10.6 |
A |
G |
17: 37,124,799 (GRCm39) |
T239A |
possibly damaging |
Het |
| Haus5 |
T |
C |
7: 30,358,825 (GRCm39) |
N237S |
possibly damaging |
Het |
| Hectd3 |
T |
C |
4: 116,857,882 (GRCm39) |
M605T |
probably damaging |
Het |
| Hps3 |
T |
C |
3: 20,084,691 (GRCm39) |
I166V |
probably benign |
Het |
| Ighv5-21 |
A |
T |
12: 114,286,434 (GRCm39) |
|
probably benign |
Het |
| Kdm6b |
C |
T |
11: 69,294,418 (GRCm39) |
G1218D |
unknown |
Het |
| Klhl30 |
A |
G |
1: 91,285,636 (GRCm39) |
|
probably null |
Het |
| Kmt2a |
A |
T |
9: 44,729,747 (GRCm39) |
S3523R |
probably benign |
Het |
| Lnpep |
A |
T |
17: 17,788,661 (GRCm39) |
N481K |
probably damaging |
Het |
| Lrp1b |
T |
C |
2: 41,231,861 (GRCm39) |
H1203R |
probably benign |
Het |
| Lrrc8a |
C |
T |
2: 30,146,661 (GRCm39) |
R492W |
probably damaging |
Het |
| Magel2 |
T |
A |
7: 62,030,342 (GRCm39) |
V1082D |
unknown |
Het |
| Memo1 |
A |
C |
17: 74,552,049 (GRCm39) |
H82Q |
probably null |
Het |
| Myh2 |
A |
T |
11: 67,085,451 (GRCm39) |
N1792Y |
possibly damaging |
Het |
| Myo1e |
A |
T |
9: 70,275,969 (GRCm39) |
N728I |
possibly damaging |
Het |
| Myo1e |
T |
C |
9: 70,285,997 (GRCm39) |
|
probably benign |
Het |
| Myo5c |
T |
C |
9: 75,196,337 (GRCm39) |
|
probably benign |
Het |
| Or11l3 |
T |
A |
11: 58,516,319 (GRCm39) |
L184F |
probably damaging |
Het |
| Or1e19 |
A |
G |
11: 73,316,188 (GRCm39) |
V207A |
probably benign |
Het |
| Or2d2b |
T |
C |
7: 106,705,643 (GRCm39) |
I142V |
probably benign |
Het |
| Or4c11c |
T |
A |
2: 88,661,749 (GRCm39) |
M96K |
possibly damaging |
Het |
| Or51g1 |
T |
A |
7: 102,633,478 (GRCm39) |
T298S |
probably damaging |
Het |
| Or52e3 |
T |
C |
7: 102,868,967 (GRCm39) |
F14S |
probably damaging |
Het |
| Parp2 |
C |
T |
14: 51,047,543 (GRCm39) |
A18V |
probably benign |
Het |
| Peli1 |
T |
A |
11: 21,098,110 (GRCm39) |
C282S |
probably damaging |
Het |
| Phf8-ps |
G |
T |
17: 33,286,598 (GRCm39) |
S68* |
probably null |
Het |
| Piezo2 |
T |
C |
18: 63,252,006 (GRCm39) |
M404V |
possibly damaging |
Het |
| Pkn1 |
T |
A |
8: 84,404,592 (GRCm39) |
Q496L |
possibly damaging |
Het |
| Pla2r1 |
A |
T |
2: 60,262,317 (GRCm39) |
F1093L |
probably damaging |
Het |
| Ppp2r3d |
A |
G |
9: 101,022,680 (GRCm39) |
V323A |
probably damaging |
Het |
| Pramel16 |
T |
A |
4: 143,676,453 (GRCm39) |
Y217F |
probably benign |
Het |
| Prg2 |
C |
T |
2: 84,812,342 (GRCm39) |
|
probably benign |
Het |
| Ptprb |
G |
A |
10: 116,182,958 (GRCm39) |
G1545S |
probably benign |
Het |
| Rbm19 |
A |
G |
5: 120,258,307 (GRCm39) |
D174G |
possibly damaging |
Het |
| Rhbdf2 |
T |
A |
11: 116,491,974 (GRCm39) |
T526S |
probably damaging |
Het |
| Rpusd4 |
A |
G |
9: 35,179,310 (GRCm39) |
N42S |
probably benign |
Het |
| Ryr3 |
T |
A |
2: 112,477,361 (GRCm39) |
Q4455L |
possibly damaging |
Het |
| Sema4a |
G |
T |
3: 88,358,668 (GRCm39) |
H30Q |
probably damaging |
Het |
| Skint1 |
G |
A |
4: 111,878,653 (GRCm39) |
|
probably null |
Het |
| Slc1a3 |
A |
G |
15: 8,675,153 (GRCm39) |
V284A |
probably benign |
Het |
| Slc30a9 |
A |
T |
5: 67,497,318 (GRCm39) |
K288* |
probably null |
Het |
| Slc36a1 |
G |
T |
11: 55,119,164 (GRCm39) |
A380S |
probably benign |
Het |
| Slc47a1 |
G |
A |
11: 61,268,833 (GRCm39) |
|
probably benign |
Het |
| Snx19 |
A |
T |
9: 30,340,296 (GRCm39) |
E478V |
probably benign |
Het |
| Spag6 |
T |
C |
2: 18,738,916 (GRCm39) |
|
probably benign |
Het |
| Stag1 |
A |
T |
9: 100,668,740 (GRCm39) |
T223S |
probably damaging |
Het |
| Terb1 |
A |
T |
8: 105,224,732 (GRCm39) |
|
probably benign |
Het |
| Terf1 |
A |
G |
1: 15,876,170 (GRCm39) |
D90G |
possibly damaging |
Het |
| Tex15 |
A |
G |
8: 34,061,302 (GRCm39) |
D518G |
probably damaging |
Het |
| Tmem174 |
T |
A |
13: 98,773,546 (GRCm39) |
M95L |
possibly damaging |
Het |
| Tnnt3 |
GTCCAGGCATCTC |
GTC |
7: 142,066,364 (GRCm39) |
|
probably benign |
Het |
| Usp28 |
A |
G |
9: 48,896,803 (GRCm39) |
D8G |
probably benign |
Het |
| Vmn2r105 |
T |
C |
17: 20,444,840 (GRCm39) |
T551A |
probably damaging |
Het |
| Vmn2r107 |
A |
G |
17: 20,595,549 (GRCm39) |
I701V |
probably benign |
Het |
| Vmn2r13 |
A |
C |
5: 109,339,943 (GRCm39) |
F11V |
probably benign |
Het |
| Vmn2r85 |
G |
C |
10: 130,261,443 (GRCm39) |
S298* |
probably null |
Het |
| Wdr6 |
C |
G |
9: 108,452,554 (GRCm39) |
W443S |
probably damaging |
Het |
| Wipi1 |
A |
G |
11: 109,474,016 (GRCm39) |
V210A |
probably damaging |
Het |
| Zfp317 |
A |
G |
9: 19,556,532 (GRCm39) |
T47A |
probably benign |
Het |
| Zfp61 |
T |
C |
7: 23,991,714 (GRCm39) |
T146A |
probably benign |
Het |
| Zfp964 |
A |
G |
8: 70,116,567 (GRCm39) |
E389G |
unknown |
Het |
| Zfyve16 |
T |
C |
13: 92,640,985 (GRCm39) |
D1253G |
probably damaging |
Het |
| Zpld2 |
T |
C |
4: 133,929,669 (GRCm39) |
K212R |
possibly damaging |
Het |
| Zswim7 |
G |
A |
11: 62,158,299 (GRCm39) |
|
probably benign |
Het |
|
| Other mutations in Myh13 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00497:Myh13
|
APN |
11 |
67,233,314 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL00808:Myh13
|
APN |
11 |
67,225,830 (GRCm39) |
critical splice donor site |
probably null |
|
|
IGL00822:Myh13
|
APN |
11 |
67,252,154 (GRCm39) |
missense |
probably damaging |
0.98 |
|
IGL00823:Myh13
|
APN |
11 |
67,246,773 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL00945:Myh13
|
APN |
11 |
67,238,832 (GRCm39) |
missense |
probably null |
1.00 |
|
IGL01414:Myh13
|
APN |
11 |
67,233,298 (GRCm39) |
missense |
probably benign |
0.02 |
|
IGL01482:Myh13
|
APN |
11 |
67,242,894 (GRCm39) |
missense |
probably benign |
|
|
IGL01523:Myh13
|
APN |
11 |
67,238,769 (GRCm39) |
missense |
possibly damaging |
0.73 |
|
IGL01723:Myh13
|
APN |
11 |
67,260,045 (GRCm39) |
unclassified |
probably benign |
|
|
IGL01997:Myh13
|
APN |
11 |
67,257,992 (GRCm39) |
missense |
probably benign |
0.14 |
|
IGL02369:Myh13
|
APN |
11 |
67,251,100 (GRCm39) |
unclassified |
probably benign |
|
|
IGL02478:Myh13
|
APN |
11 |
67,260,204 (GRCm39) |
missense |
probably benign |
|
|
IGL02663:Myh13
|
APN |
11 |
67,245,753 (GRCm39) |
nonsense |
probably null |
|
|
IGL02851:Myh13
|
APN |
11 |
67,239,742 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
IGL02863:Myh13
|
APN |
11 |
67,223,367 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02929:Myh13
|
APN |
11 |
67,257,991 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02979:Myh13
|
APN |
11 |
67,225,788 (GRCm39) |
missense |
possibly damaging |
0.72 |
|
IGL03065:Myh13
|
APN |
11 |
67,235,679 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL03214:Myh13
|
APN |
11 |
67,244,411 (GRCm39) |
missense |
possibly damaging |
0.79 |
|
IGL03223:Myh13
|
APN |
11 |
67,241,068 (GRCm39) |
missense |
probably benign |
0.39 |
|
IGL03231:Myh13
|
APN |
11 |
67,242,817 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
IGL03407:Myh13
|
APN |
11 |
67,242,978 (GRCm39) |
missense |
probably damaging |
1.00 |
|
3-1:Myh13
|
UTSW |
11 |
67,242,777 (GRCm39) |
splice site |
probably benign |
|
|
P0042:Myh13
|
UTSW |
11 |
67,225,817 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0047:Myh13
|
UTSW |
11 |
67,258,063 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0047:Myh13
|
UTSW |
11 |
67,258,063 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0379:Myh13
|
UTSW |
11 |
67,260,121 (GRCm39) |
unclassified |
probably benign |
|
|
R0496:Myh13
|
UTSW |
11 |
67,239,641 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0584:Myh13
|
UTSW |
11 |
67,251,200 (GRCm39) |
nonsense |
probably null |
|
|
R0595:Myh13
|
UTSW |
11 |
67,235,672 (GRCm39) |
missense |
probably benign |
0.03 |
|
R0621:Myh13
|
UTSW |
11 |
67,232,058 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R0834:Myh13
|
UTSW |
11 |
67,240,436 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
R0893:Myh13
|
UTSW |
11 |
67,225,427 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0964:Myh13
|
UTSW |
11 |
67,235,828 (GRCm39) |
missense |
probably benign |
0.02 |
|
R0973:Myh13
|
UTSW |
11 |
67,223,346 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0973:Myh13
|
UTSW |
11 |
67,223,346 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0974:Myh13
|
UTSW |
11 |
67,223,346 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1028:Myh13
|
UTSW |
11 |
67,247,007 (GRCm39) |
missense |
possibly damaging |
0.71 |
|
R1112:Myh13
|
UTSW |
11 |
67,245,576 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1283:Myh13
|
UTSW |
11 |
67,261,747 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1288:Myh13
|
UTSW |
11 |
67,244,544 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1386:Myh13
|
UTSW |
11 |
67,261,776 (GRCm39) |
missense |
possibly damaging |
0.79 |
|
R1457:Myh13
|
UTSW |
11 |
67,221,872 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R1503:Myh13
|
UTSW |
11 |
67,244,500 (GRCm39) |
missense |
probably benign |
0.43 |
|
R1574:Myh13
|
UTSW |
11 |
67,253,407 (GRCm39) |
unclassified |
probably benign |
|
|
R1673:Myh13
|
UTSW |
11 |
67,242,945 (GRCm39) |
missense |
possibly damaging |
0.79 |
|
R1693:Myh13
|
UTSW |
11 |
67,232,310 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R1763:Myh13
|
UTSW |
11 |
67,225,402 (GRCm39) |
missense |
probably benign |
|
|
R2030:Myh13
|
UTSW |
11 |
67,241,064 (GRCm39) |
missense |
probably benign |
|
|
R2247:Myh13
|
UTSW |
11 |
67,225,384 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R2393:Myh13
|
UTSW |
11 |
67,231,184 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R2395:Myh13
|
UTSW |
11 |
67,255,748 (GRCm39) |
missense |
probably benign |
0.12 |
|
R2884:Myh13
|
UTSW |
11 |
67,228,469 (GRCm39) |
missense |
probably benign |
0.27 |
|
R3696:Myh13
|
UTSW |
11 |
67,235,870 (GRCm39) |
missense |
possibly damaging |
0.55 |
|
R3786:Myh13
|
UTSW |
11 |
67,218,014 (GRCm39) |
missense |
probably benign |
0.01 |
|
R3875:Myh13
|
UTSW |
11 |
67,249,020 (GRCm39) |
missense |
probably benign |
0.26 |
|
R3918:Myh13
|
UTSW |
11 |
67,220,064 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4061:Myh13
|
UTSW |
11 |
67,221,715 (GRCm39) |
missense |
possibly damaging |
0.71 |
|
R4160:Myh13
|
UTSW |
11 |
67,255,636 (GRCm39) |
intron |
probably benign |
|
|
R4183:Myh13
|
UTSW |
11 |
67,240,436 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
R4392:Myh13
|
UTSW |
11 |
67,235,707 (GRCm39) |
splice site |
probably null |
|
|
R4639:Myh13
|
UTSW |
11 |
67,232,377 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R4670:Myh13
|
UTSW |
11 |
67,255,564 (GRCm39) |
nonsense |
probably null |
|
|
R4783:Myh13
|
UTSW |
11 |
67,232,096 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4877:Myh13
|
UTSW |
11 |
67,228,477 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5250:Myh13
|
UTSW |
11 |
67,218,085 (GRCm39) |
nonsense |
probably null |
|
|
R5278:Myh13
|
UTSW |
11 |
67,225,390 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5371:Myh13
|
UTSW |
11 |
67,235,616 (GRCm39) |
splice site |
probably null |
|
|
R5479:Myh13
|
UTSW |
11 |
67,239,648 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R5510:Myh13
|
UTSW |
11 |
67,228,549 (GRCm39) |
missense |
probably benign |
0.05 |
|
R5690:Myh13
|
UTSW |
11 |
67,220,101 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5797:Myh13
|
UTSW |
11 |
67,225,828 (GRCm39) |
missense |
possibly damaging |
0.66 |
|
R5823:Myh13
|
UTSW |
11 |
67,251,294 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5877:Myh13
|
UTSW |
11 |
67,244,484 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
R6041:Myh13
|
UTSW |
11 |
67,255,556 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6175:Myh13
|
UTSW |
11 |
67,245,588 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6244:Myh13
|
UTSW |
11 |
67,253,327 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6454:Myh13
|
UTSW |
11 |
67,241,191 (GRCm39) |
missense |
probably benign |
0.03 |
|
R6617:Myh13
|
UTSW |
11 |
67,252,226 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6707:Myh13
|
UTSW |
11 |
67,241,086 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6747:Myh13
|
UTSW |
11 |
67,241,245 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6823:Myh13
|
UTSW |
11 |
67,246,984 (GRCm39) |
missense |
probably benign |
|
|
R6911:Myh13
|
UTSW |
11 |
67,245,753 (GRCm39) |
nonsense |
probably null |
|
|
R6997:Myh13
|
UTSW |
11 |
67,217,980 (GRCm39) |
nonsense |
probably null |
|
|
R7033:Myh13
|
UTSW |
11 |
67,260,142 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R7145:Myh13
|
UTSW |
11 |
67,245,566 (GRCm39) |
missense |
probably benign |
0.08 |
|
R7232:Myh13
|
UTSW |
11 |
67,239,672 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7428:Myh13
|
UTSW |
11 |
67,223,390 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7448:Myh13
|
UTSW |
11 |
67,255,286 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R7474:Myh13
|
UTSW |
11 |
67,258,537 (GRCm39) |
missense |
|
|
|
R7474:Myh13
|
UTSW |
11 |
67,217,990 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R7766:Myh13
|
UTSW |
11 |
67,249,155 (GRCm39) |
missense |
probably benign |
0.37 |
|
R7809:Myh13
|
UTSW |
11 |
67,241,167 (GRCm39) |
missense |
probably benign |
0.14 |
|
R7813:Myh13
|
UTSW |
11 |
67,218,056 (GRCm39) |
missense |
probably benign |
0.27 |
|
R7953:Myh13
|
UTSW |
11 |
67,231,206 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8085:Myh13
|
UTSW |
11 |
67,225,613 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8397:Myh13
|
UTSW |
11 |
67,241,113 (GRCm39) |
missense |
possibly damaging |
0.62 |
|
R8434:Myh13
|
UTSW |
11 |
67,254,011 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R8490:Myh13
|
UTSW |
11 |
67,255,351 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R8676:Myh13
|
UTSW |
11 |
67,233,311 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8681:Myh13
|
UTSW |
11 |
67,242,960 (GRCm39) |
missense |
possibly damaging |
0.49 |
|
R8777:Myh13
|
UTSW |
11 |
67,252,161 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R8777-TAIL:Myh13
|
UTSW |
11 |
67,252,161 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R8965:Myh13
|
UTSW |
11 |
67,255,432 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9088:Myh13
|
UTSW |
11 |
67,242,885 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9151:Myh13
|
UTSW |
11 |
67,252,149 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9154:Myh13
|
UTSW |
11 |
67,253,318 (GRCm39) |
missense |
probably benign |
|
|
R9182:Myh13
|
UTSW |
11 |
67,228,579 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9332:Myh13
|
UTSW |
11 |
67,254,109 (GRCm39) |
missense |
possibly damaging |
0.57 |
|
R9393:Myh13
|
UTSW |
11 |
67,242,894 (GRCm39) |
missense |
probably benign |
|
|
R9446:Myh13
|
UTSW |
11 |
67,255,325 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9474:Myh13
|
UTSW |
11 |
67,255,712 (GRCm39) |
missense |
|
|
|
R9690:Myh13
|
UTSW |
11 |
67,249,194 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9761:Myh13
|
UTSW |
11 |
67,251,294 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9778:Myh13
|
UTSW |
11 |
67,249,016 (GRCm39) |
missense |
probably damaging |
0.98 |
|
Z1176:Myh13
|
UTSW |
11 |
67,220,121 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
Z1177:Myh13
|
UTSW |
11 |
67,255,417 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
Z1177:Myh13
|
UTSW |
11 |
67,241,278 (GRCm39) |
missense |
possibly damaging |
0.55 |
|
| Predicted Primers |
PCR Primer
(F):5'- ATGTGCACATGACTACACAGGAC -3'
(R):5'- GTGCAGCTTAGAATGCACGTG -3'
Sequencing Primer
(F):5'- GACCCTCCACTCACATCTGGG -3'
(R):5'- GAGGAGACCACCATGTCCATG -3'
|
| Posted On |
2014-08-25 |
Incidental Mutation