Incidental Mutation 'R2029:Dop1b'
| ID |
221056 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Dop1b
|
| Ensembl Gene |
ENSMUSG00000022946 |
| Gene Name |
DOP1 leucine zipper like protein B |
| Synonyms |
Dopey2, 0610038M01Rik, 2610510B01Rik |
| MMRRC Submission |
040036-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R2029 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
|
| Chromosome |
16 |
| Chromosomal Location |
93508795-93607476 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to G
at 93566323 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Lysine to Glutamic Acid
at position 917
(K917E)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000154771
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000045004]
[ENSMUST00000227156]
|
| AlphaFold |
Q3UHQ6 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000045004
AA Change: K1035E
PolyPhen 2
Score 0.242 (Sensitivity: 0.91; Specificity: 0.88)
|
| SMART Domains |
Protein: ENSMUSP00000044437
Gene: ENSMUSG00000022946
AA Change: K1035E
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:Dopey_N
|
11 |
308 |
3.9e-104 |
PFAM |
|
low complexity region
|
651 |
666 |
N/A |
INTRINSIC |
|
low complexity region
|
709 |
719 |
N/A |
INTRINSIC |
|
low complexity region
|
747 |
759 |
N/A |
INTRINSIC |
|
low complexity region
|
1186 |
1199 |
N/A |
INTRINSIC |
|
low complexity region
|
1436 |
1451 |
N/A |
INTRINSIC |
|
low complexity region
|
1893 |
1908 |
N/A |
INTRINSIC |
|
| Predicted Effect |
unknown
Transcript: ENSMUST00000226215
AA Change: K245E
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000226535
|
| Predicted Effect |
unknown
Transcript: ENSMUST00000226836
AA Change: K197E
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000227156
AA Change: K917E
PolyPhen 2
Score 0.356 (Sensitivity: 0.90; Specificity: 0.89)
|
| Meta Mutation Damage Score |
0.0898 |
| Coding Region Coverage |
- 1x: 99.2%
- 3x: 98.5%
- 10x: 96.8%
- 20x: 93.8%
|
| Validation Efficiency |
98% (97/99) |
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 100 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Adam18 |
C |
G |
8: 25,140,893 (GRCm39) |
G286A |
probably damaging |
Het |
| Adcy1 |
G |
A |
11: 7,089,142 (GRCm39) |
A519T |
probably benign |
Het |
| Anxa2 |
T |
A |
9: 69,371,762 (GRCm39) |
S2T |
possibly damaging |
Het |
| Ap3m1 |
G |
A |
14: 21,089,217 (GRCm39) |
S261L |
possibly damaging |
Het |
| Baz2b |
A |
T |
2: 59,743,067 (GRCm39) |
|
probably benign |
Het |
| Brdt |
T |
A |
5: 107,507,090 (GRCm39) |
S497T |
probably benign |
Het |
| Cdh11 |
A |
G |
8: 103,406,404 (GRCm39) |
F23S |
probably benign |
Het |
| Cdh16 |
A |
C |
8: 105,344,434 (GRCm39) |
L540R |
probably damaging |
Het |
| Ces5a |
A |
T |
8: 94,261,205 (GRCm39) |
L74Q |
probably damaging |
Het |
| Cfap69 |
A |
G |
5: 5,654,306 (GRCm39) |
S543P |
probably damaging |
Het |
| Cfap74 |
T |
C |
4: 155,526,538 (GRCm39) |
I763T |
possibly damaging |
Het |
| Cma1 |
T |
A |
14: 56,181,191 (GRCm39) |
R58S |
possibly damaging |
Het |
| Csmd3 |
C |
T |
15: 47,701,975 (GRCm39) |
D1599N |
probably damaging |
Het |
| Cyld |
A |
G |
8: 89,471,940 (GRCm39) |
K857R |
probably benign |
Het |
| Cyp3a16 |
T |
C |
5: 145,388,667 (GRCm39) |
D270G |
probably damaging |
Het |
| D1Pas1 |
T |
C |
1: 186,700,286 (GRCm39) |
S72P |
possibly damaging |
Het |
| Ddx3y |
T |
C |
Y: 1,266,389 (GRCm39) |
E331G |
probably benign |
Het |
| Degs1l |
T |
A |
1: 180,882,496 (GRCm39) |
I86K |
probably benign |
Het |
| Dis3l2 |
T |
C |
1: 86,782,189 (GRCm39) |
|
probably benign |
Het |
| Dop1a |
G |
T |
9: 86,403,418 (GRCm39) |
W1539C |
probably damaging |
Het |
| Ecpas |
G |
A |
4: 58,844,165 (GRCm39) |
R534* |
probably null |
Het |
| Efcab3 |
T |
C |
11: 104,990,851 (GRCm39) |
I5462T |
probably damaging |
Het |
| Eif1ad15 |
A |
T |
12: 88,288,191 (GRCm39) |
S21T |
unknown |
Het |
| Epo |
A |
G |
5: 137,483,447 (GRCm39) |
|
probably benign |
Het |
| Figla |
T |
A |
6: 85,997,624 (GRCm39) |
|
probably benign |
Het |
| Flvcr1 |
T |
C |
1: 190,753,353 (GRCm39) |
D273G |
probably benign |
Het |
| Fryl |
T |
A |
5: 73,179,465 (GRCm39) |
R304* |
probably null |
Het |
| Gcm1 |
T |
G |
9: 77,972,326 (GRCm39) |
D422E |
possibly damaging |
Het |
| Get3 |
A |
T |
8: 85,746,403 (GRCm39) |
Y148* |
probably null |
Het |
| Ggt6 |
A |
G |
11: 72,328,367 (GRCm39) |
D251G |
possibly damaging |
Het |
| Git2 |
A |
G |
5: 114,904,511 (GRCm39) |
|
probably null |
Het |
| Gm18856 |
A |
T |
13: 14,139,376 (GRCm39) |
|
probably benign |
Het |
| Gm20939 |
T |
A |
17: 95,183,252 (GRCm39) |
|
probably benign |
Het |
| Gpr176 |
A |
G |
2: 118,109,913 (GRCm39) |
Y449H |
probably benign |
Het |
| H2-Eb1 |
A |
G |
17: 34,533,366 (GRCm39) |
E196G |
probably damaging |
Het |
| H2-M10.6 |
A |
G |
17: 37,124,799 (GRCm39) |
T239A |
possibly damaging |
Het |
| Haus5 |
T |
C |
7: 30,358,825 (GRCm39) |
N237S |
possibly damaging |
Het |
| Hectd3 |
T |
C |
4: 116,857,882 (GRCm39) |
M605T |
probably damaging |
Het |
| Hps3 |
T |
C |
3: 20,084,691 (GRCm39) |
I166V |
probably benign |
Het |
| Ighv5-21 |
A |
T |
12: 114,286,434 (GRCm39) |
|
probably benign |
Het |
| Kdm6b |
C |
T |
11: 69,294,418 (GRCm39) |
G1218D |
unknown |
Het |
| Klhl30 |
A |
G |
1: 91,285,636 (GRCm39) |
|
probably null |
Het |
| Kmt2a |
A |
T |
9: 44,729,747 (GRCm39) |
S3523R |
probably benign |
Het |
| Lnpep |
A |
T |
17: 17,788,661 (GRCm39) |
N481K |
probably damaging |
Het |
| Lrp1b |
T |
C |
2: 41,231,861 (GRCm39) |
H1203R |
probably benign |
Het |
| Lrrc8a |
C |
T |
2: 30,146,661 (GRCm39) |
R492W |
probably damaging |
Het |
| Magel2 |
T |
A |
7: 62,030,342 (GRCm39) |
V1082D |
unknown |
Het |
| Memo1 |
A |
C |
17: 74,552,049 (GRCm39) |
H82Q |
probably null |
Het |
| Myh13 |
A |
T |
11: 67,252,115 (GRCm39) |
T1408S |
probably benign |
Het |
| Myh2 |
A |
T |
11: 67,085,451 (GRCm39) |
N1792Y |
possibly damaging |
Het |
| Myo1e |
A |
T |
9: 70,275,969 (GRCm39) |
N728I |
possibly damaging |
Het |
| Myo1e |
T |
C |
9: 70,285,997 (GRCm39) |
|
probably benign |
Het |
| Myo5c |
T |
C |
9: 75,196,337 (GRCm39) |
|
probably benign |
Het |
| Or11l3 |
T |
A |
11: 58,516,319 (GRCm39) |
L184F |
probably damaging |
Het |
| Or1e19 |
A |
G |
11: 73,316,188 (GRCm39) |
V207A |
probably benign |
Het |
| Or2d2b |
T |
C |
7: 106,705,643 (GRCm39) |
I142V |
probably benign |
Het |
| Or4c11c |
T |
A |
2: 88,661,749 (GRCm39) |
M96K |
possibly damaging |
Het |
| Or51g1 |
T |
A |
7: 102,633,478 (GRCm39) |
T298S |
probably damaging |
Het |
| Or52e3 |
T |
C |
7: 102,868,967 (GRCm39) |
F14S |
probably damaging |
Het |
| Parp2 |
C |
T |
14: 51,047,543 (GRCm39) |
A18V |
probably benign |
Het |
| Peli1 |
T |
A |
11: 21,098,110 (GRCm39) |
C282S |
probably damaging |
Het |
| Phf8-ps |
G |
T |
17: 33,286,598 (GRCm39) |
S68* |
probably null |
Het |
| Piezo2 |
T |
C |
18: 63,252,006 (GRCm39) |
M404V |
possibly damaging |
Het |
| Pkn1 |
T |
A |
8: 84,404,592 (GRCm39) |
Q496L |
possibly damaging |
Het |
| Pla2r1 |
A |
T |
2: 60,262,317 (GRCm39) |
F1093L |
probably damaging |
Het |
| Ppp2r3d |
A |
G |
9: 101,022,680 (GRCm39) |
V323A |
probably damaging |
Het |
| Pramel16 |
T |
A |
4: 143,676,453 (GRCm39) |
Y217F |
probably benign |
Het |
| Prg2 |
C |
T |
2: 84,812,342 (GRCm39) |
|
probably benign |
Het |
| Ptprb |
G |
A |
10: 116,182,958 (GRCm39) |
G1545S |
probably benign |
Het |
| Rbm19 |
A |
G |
5: 120,258,307 (GRCm39) |
D174G |
possibly damaging |
Het |
| Rhbdf2 |
T |
A |
11: 116,491,974 (GRCm39) |
T526S |
probably damaging |
Het |
| Rpusd4 |
A |
G |
9: 35,179,310 (GRCm39) |
N42S |
probably benign |
Het |
| Ryr3 |
T |
A |
2: 112,477,361 (GRCm39) |
Q4455L |
possibly damaging |
Het |
| Sema4a |
G |
T |
3: 88,358,668 (GRCm39) |
H30Q |
probably damaging |
Het |
| Skint1 |
G |
A |
4: 111,878,653 (GRCm39) |
|
probably null |
Het |
| Slc1a3 |
A |
G |
15: 8,675,153 (GRCm39) |
V284A |
probably benign |
Het |
| Slc30a9 |
A |
T |
5: 67,497,318 (GRCm39) |
K288* |
probably null |
Het |
| Slc36a1 |
G |
T |
11: 55,119,164 (GRCm39) |
A380S |
probably benign |
Het |
| Slc47a1 |
G |
A |
11: 61,268,833 (GRCm39) |
|
probably benign |
Het |
| Snx19 |
A |
T |
9: 30,340,296 (GRCm39) |
E478V |
probably benign |
Het |
| Spag6 |
T |
C |
2: 18,738,916 (GRCm39) |
|
probably benign |
Het |
| Stag1 |
A |
T |
9: 100,668,740 (GRCm39) |
T223S |
probably damaging |
Het |
| Terb1 |
A |
T |
8: 105,224,732 (GRCm39) |
|
probably benign |
Het |
| Terf1 |
A |
G |
1: 15,876,170 (GRCm39) |
D90G |
possibly damaging |
Het |
| Tex15 |
A |
G |
8: 34,061,302 (GRCm39) |
D518G |
probably damaging |
Het |
| Tmem174 |
T |
A |
13: 98,773,546 (GRCm39) |
M95L |
possibly damaging |
Het |
| Tnnt3 |
GTCCAGGCATCTC |
GTC |
7: 142,066,364 (GRCm39) |
|
probably benign |
Het |
| Usp28 |
A |
G |
9: 48,896,803 (GRCm39) |
D8G |
probably benign |
Het |
| Vmn2r105 |
T |
C |
17: 20,444,840 (GRCm39) |
T551A |
probably damaging |
Het |
| Vmn2r107 |
A |
G |
17: 20,595,549 (GRCm39) |
I701V |
probably benign |
Het |
| Vmn2r13 |
A |
C |
5: 109,339,943 (GRCm39) |
F11V |
probably benign |
Het |
| Vmn2r85 |
G |
C |
10: 130,261,443 (GRCm39) |
S298* |
probably null |
Het |
| Wdr6 |
C |
G |
9: 108,452,554 (GRCm39) |
W443S |
probably damaging |
Het |
| Wipi1 |
A |
G |
11: 109,474,016 (GRCm39) |
V210A |
probably damaging |
Het |
| Zfp317 |
A |
G |
9: 19,556,532 (GRCm39) |
T47A |
probably benign |
Het |
| Zfp61 |
T |
C |
7: 23,991,714 (GRCm39) |
T146A |
probably benign |
Het |
| Zfp964 |
A |
G |
8: 70,116,567 (GRCm39) |
E389G |
unknown |
Het |
| Zfyve16 |
T |
C |
13: 92,640,985 (GRCm39) |
D1253G |
probably damaging |
Het |
| Zpld2 |
T |
C |
4: 133,929,669 (GRCm39) |
K212R |
possibly damaging |
Het |
| Zswim7 |
G |
A |
11: 62,158,299 (GRCm39) |
|
probably benign |
Het |
|
| Other mutations in Dop1b |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00476:Dop1b
|
APN |
16 |
93,596,914 (GRCm39) |
unclassified |
probably benign |
|
|
IGL00492:Dop1b
|
APN |
16 |
93,577,670 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL00753:Dop1b
|
APN |
16 |
93,566,512 (GRCm39) |
missense |
probably benign |
|
|
IGL00832:Dop1b
|
APN |
16 |
93,560,289 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL00939:Dop1b
|
APN |
16 |
93,570,971 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
IGL01019:Dop1b
|
APN |
16 |
93,607,117 (GRCm39) |
missense |
probably benign |
0.32 |
|
IGL01288:Dop1b
|
APN |
16 |
93,536,181 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
IGL01505:Dop1b
|
APN |
16 |
93,554,004 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
IGL01535:Dop1b
|
APN |
16 |
93,566,846 (GRCm39) |
nonsense |
probably null |
|
|
IGL01696:Dop1b
|
APN |
16 |
93,567,128 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL02077:Dop1b
|
APN |
16 |
93,577,648 (GRCm39) |
missense |
probably damaging |
0.96 |
|
IGL02163:Dop1b
|
APN |
16 |
93,559,315 (GRCm39) |
missense |
possibly damaging |
0.48 |
|
IGL02234:Dop1b
|
APN |
16 |
93,549,039 (GRCm39) |
missense |
probably benign |
|
|
IGL02302:Dop1b
|
APN |
16 |
93,607,005 (GRCm39) |
missense |
probably benign |
0.08 |
|
IGL02485:Dop1b
|
APN |
16 |
93,567,710 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02563:Dop1b
|
APN |
16 |
93,574,293 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL02733:Dop1b
|
APN |
16 |
93,536,079 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
IGL02792:Dop1b
|
APN |
16 |
93,598,460 (GRCm39) |
missense |
possibly damaging |
0.75 |
|
IGL02941:Dop1b
|
APN |
16 |
93,552,361 (GRCm39) |
missense |
probably benign |
0.09 |
|
IGL03143:Dop1b
|
APN |
16 |
93,556,543 (GRCm39) |
missense |
probably benign |
|
|
PIT4519001:Dop1b
|
UTSW |
16 |
93,558,942 (GRCm39) |
missense |
probably benign |
|
|
R0320:Dop1b
|
UTSW |
16 |
93,607,035 (GRCm39) |
missense |
probably benign |
0.02 |
|
R0499:Dop1b
|
UTSW |
16 |
93,567,325 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0501:Dop1b
|
UTSW |
16 |
93,549,750 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0534:Dop1b
|
UTSW |
16 |
93,559,393 (GRCm39) |
missense |
probably benign |
0.04 |
|
R0583:Dop1b
|
UTSW |
16 |
93,552,374 (GRCm39) |
missense |
probably benign |
0.30 |
|
R0626:Dop1b
|
UTSW |
16 |
93,560,844 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0724:Dop1b
|
UTSW |
16 |
93,559,213 (GRCm39) |
missense |
probably benign |
0.01 |
|
R0907:Dop1b
|
UTSW |
16 |
93,598,481 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1263:Dop1b
|
UTSW |
16 |
93,574,274 (GRCm39) |
missense |
probably benign |
|
|
R1378:Dop1b
|
UTSW |
16 |
93,567,280 (GRCm39) |
missense |
probably benign |
|
|
R1572:Dop1b
|
UTSW |
16 |
93,567,041 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1604:Dop1b
|
UTSW |
16 |
93,559,458 (GRCm39) |
missense |
probably benign |
|
|
R1642:Dop1b
|
UTSW |
16 |
93,559,203 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1668:Dop1b
|
UTSW |
16 |
93,562,404 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1669:Dop1b
|
UTSW |
16 |
93,566,548 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1702:Dop1b
|
UTSW |
16 |
93,544,509 (GRCm39) |
missense |
possibly damaging |
0.47 |
|
R1711:Dop1b
|
UTSW |
16 |
93,596,814 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1917:Dop1b
|
UTSW |
16 |
93,513,150 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1968:Dop1b
|
UTSW |
16 |
93,579,307 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1988:Dop1b
|
UTSW |
16 |
93,563,061 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2139:Dop1b
|
UTSW |
16 |
93,567,895 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
R2355:Dop1b
|
UTSW |
16 |
93,567,565 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3609:Dop1b
|
UTSW |
16 |
93,536,220 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3792:Dop1b
|
UTSW |
16 |
93,568,734 (GRCm39) |
missense |
possibly damaging |
0.54 |
|
R4364:Dop1b
|
UTSW |
16 |
93,567,812 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4380:Dop1b
|
UTSW |
16 |
93,513,120 (GRCm39) |
missense |
possibly damaging |
0.53 |
|
R4455:Dop1b
|
UTSW |
16 |
93,563,103 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4779:Dop1b
|
UTSW |
16 |
93,553,969 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4820:Dop1b
|
UTSW |
16 |
93,589,978 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4834:Dop1b
|
UTSW |
16 |
93,536,892 (GRCm39) |
start codon destroyed |
probably null |
0.70 |
|
R4866:Dop1b
|
UTSW |
16 |
93,560,318 (GRCm39) |
critical splice donor site |
probably null |
|
|
R4882:Dop1b
|
UTSW |
16 |
93,549,802 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R4900:Dop1b
|
UTSW |
16 |
93,560,318 (GRCm39) |
critical splice donor site |
probably null |
|
|
R5153:Dop1b
|
UTSW |
16 |
93,570,891 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R5176:Dop1b
|
UTSW |
16 |
93,536,931 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5206:Dop1b
|
UTSW |
16 |
93,598,472 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5320:Dop1b
|
UTSW |
16 |
93,536,874 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5361:Dop1b
|
UTSW |
16 |
93,567,392 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5380:Dop1b
|
UTSW |
16 |
93,560,298 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R5476:Dop1b
|
UTSW |
16 |
93,570,801 (GRCm39) |
splice site |
probably null |
|
|
R5502:Dop1b
|
UTSW |
16 |
93,590,114 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5543:Dop1b
|
UTSW |
16 |
93,595,808 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R5557:Dop1b
|
UTSW |
16 |
93,560,819 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R5901:Dop1b
|
UTSW |
16 |
93,566,639 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
R5907:Dop1b
|
UTSW |
16 |
93,598,469 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6174:Dop1b
|
UTSW |
16 |
93,563,110 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6256:Dop1b
|
UTSW |
16 |
93,604,102 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R6383:Dop1b
|
UTSW |
16 |
93,579,136 (GRCm39) |
missense |
possibly damaging |
0.76 |
|
R6525:Dop1b
|
UTSW |
16 |
93,606,304 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6554:Dop1b
|
UTSW |
16 |
93,557,346 (GRCm39) |
missense |
probably benign |
0.22 |
|
R6823:Dop1b
|
UTSW |
16 |
93,552,373 (GRCm39) |
missense |
possibly damaging |
0.75 |
|
R7036:Dop1b
|
UTSW |
16 |
93,574,378 (GRCm39) |
missense |
probably benign |
0.01 |
|
R7058:Dop1b
|
UTSW |
16 |
93,573,878 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7061:Dop1b
|
UTSW |
16 |
93,558,951 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7209:Dop1b
|
UTSW |
16 |
93,566,733 (GRCm39) |
missense |
probably benign |
|
|
R7214:Dop1b
|
UTSW |
16 |
93,607,023 (GRCm39) |
missense |
possibly damaging |
0.69 |
|
R7232:Dop1b
|
UTSW |
16 |
93,557,373 (GRCm39) |
critical splice donor site |
probably null |
|
|
R7255:Dop1b
|
UTSW |
16 |
93,567,034 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7335:Dop1b
|
UTSW |
16 |
93,544,396 (GRCm39) |
missense |
probably benign |
0.04 |
|
R7535:Dop1b
|
UTSW |
16 |
93,603,249 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7700:Dop1b
|
UTSW |
16 |
93,595,649 (GRCm39) |
splice site |
probably null |
|
|
R7763:Dop1b
|
UTSW |
16 |
93,552,402 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7814:Dop1b
|
UTSW |
16 |
93,596,859 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7839:Dop1b
|
UTSW |
16 |
93,560,829 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7862:Dop1b
|
UTSW |
16 |
93,546,851 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7894:Dop1b
|
UTSW |
16 |
93,607,092 (GRCm39) |
missense |
probably benign |
0.01 |
|
R7952:Dop1b
|
UTSW |
16 |
93,546,848 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R7956:Dop1b
|
UTSW |
16 |
93,567,916 (GRCm39) |
critical splice donor site |
probably null |
|
|
R8033:Dop1b
|
UTSW |
16 |
93,566,371 (GRCm39) |
missense |
probably benign |
|
|
R8061:Dop1b
|
UTSW |
16 |
93,546,884 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8067:Dop1b
|
UTSW |
16 |
93,562,336 (GRCm39) |
nonsense |
probably null |
|
|
R8146:Dop1b
|
UTSW |
16 |
93,546,827 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R8184:Dop1b
|
UTSW |
16 |
93,573,881 (GRCm39) |
missense |
probably benign |
0.13 |
|
R8221:Dop1b
|
UTSW |
16 |
93,546,847 (GRCm39) |
missense |
probably benign |
0.01 |
|
R8263:Dop1b
|
UTSW |
16 |
93,559,083 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
R8329:Dop1b
|
UTSW |
16 |
93,568,675 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8555:Dop1b
|
UTSW |
16 |
93,568,698 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8683:Dop1b
|
UTSW |
16 |
93,570,809 (GRCm39) |
missense |
probably benign |
|
|
R8683:Dop1b
|
UTSW |
16 |
93,568,699 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R8716:Dop1b
|
UTSW |
16 |
93,577,673 (GRCm39) |
nonsense |
probably null |
|
|
R8807:Dop1b
|
UTSW |
16 |
93,558,973 (GRCm39) |
missense |
probably benign |
0.03 |
|
R8840:Dop1b
|
UTSW |
16 |
93,607,005 (GRCm39) |
missense |
probably benign |
0.08 |
|
R8851:Dop1b
|
UTSW |
16 |
93,559,398 (GRCm39) |
missense |
probably benign |
0.39 |
|
R8884:Dop1b
|
UTSW |
16 |
93,556,550 (GRCm39) |
missense |
probably benign |
|
|
R8976:Dop1b
|
UTSW |
16 |
93,558,969 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9219:Dop1b
|
UTSW |
16 |
93,567,184 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9238:Dop1b
|
UTSW |
16 |
93,546,018 (GRCm39) |
missense |
probably benign |
0.14 |
|
R9284:Dop1b
|
UTSW |
16 |
93,557,196 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9289:Dop1b
|
UTSW |
16 |
93,568,681 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9298:Dop1b
|
UTSW |
16 |
93,597,087 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R9338:Dop1b
|
UTSW |
16 |
93,600,448 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9346:Dop1b
|
UTSW |
16 |
93,577,702 (GRCm39) |
critical splice donor site |
probably null |
|
|
R9444:Dop1b
|
UTSW |
16 |
93,607,127 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9500:Dop1b
|
UTSW |
16 |
93,607,171 (GRCm39) |
missense |
probably benign |
|
|
R9601:Dop1b
|
UTSW |
16 |
93,544,531 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
R9793:Dop1b
|
UTSW |
16 |
93,598,503 (GRCm39) |
missense |
probably benign |
0.30 |
|
Z1088:Dop1b
|
UTSW |
16 |
93,560,214 (GRCm39) |
missense |
probably benign |
0.00 |
|
Z1176:Dop1b
|
UTSW |
16 |
93,604,756 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
Z1176:Dop1b
|
UTSW |
16 |
93,600,434 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1176:Dop1b
|
UTSW |
16 |
93,566,469 (GRCm39) |
missense |
probably benign |
0.00 |
|
Z1177:Dop1b
|
UTSW |
16 |
93,560,783 (GRCm39) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- GGACAATTTTACAATGCTCTGTCTC -3'
(R):5'- TCGTGTCTGCAGACTCTGTG -3'
Sequencing Primer
(F):5'- CTGTTTTGCCCATGACTTGATACAG -3'
(R):5'- CCTGTCTGGAAGGTCCACATAGTAG -3'
|
| Posted On |
2014-08-25 |
Incidental Mutation