Incidental Mutation 'R0139:Mtus1'
| ID |
22185 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Mtus1
|
| Ensembl Gene |
ENSMUSG00000045636 |
| Gene Name |
mitochondrial tumor suppressor 1 |
| Synonyms |
MTSG1, B430305I03Rik, MD44, Atip1 |
| MMRRC Submission |
038424-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.241)
|
| Stock # |
R0139 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
(trace)
|
| Chromosome |
8 |
| Chromosomal Location |
41443951-41586763 bp(-) (GRCm39) |
| Type of Mutation |
splice site |
| DNA Base Change (assembly) |
G to A
at 41469233 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000121605
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000051379]
[ENSMUST00000059115]
[ENSMUST00000093534]
[ENSMUST00000117735]
[ENSMUST00000118835]
[ENSMUST00000131965]
|
| AlphaFold |
no structure available at present |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000051379
|
| SMART Domains |
Protein: ENSMUSP00000053554
Gene: ENSMUSG00000045636
| Domain | Start | End | E-Value | Type |
|---|
|
coiled coil region
|
106 |
168 |
N/A |
INTRINSIC |
|
coiled coil region
|
193 |
375 |
N/A |
INTRINSIC |
|
low complexity region
|
425 |
439 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000059115
|
| SMART Domains |
Protein: ENSMUSP00000059503
Gene: ENSMUSG00000045636
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
524 |
539 |
N/A |
INTRINSIC |
|
coiled coil region
|
876 |
938 |
N/A |
INTRINSIC |
|
SCOP:d1eq1a_
|
1021 |
1156 |
3e-7 |
SMART |
|
low complexity region
|
1195 |
1209 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000093534
|
| SMART Domains |
Protein: ENSMUSP00000091252
Gene: ENSMUSG00000045636
| Domain | Start | End | E-Value | Type |
|---|
|
coiled coil region
|
186 |
248 |
N/A |
INTRINSIC |
|
coiled coil region
|
273 |
455 |
N/A |
INTRINSIC |
|
low complexity region
|
505 |
519 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000117735
|
| SMART Domains |
Protein: ENSMUSP00000113082
Gene: ENSMUSG00000045636
| Domain | Start | End | E-Value | Type |
|---|
|
coiled coil region
|
16 |
74 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000118835
|
| SMART Domains |
Protein: ENSMUSP00000112626
Gene: ENSMUSG00000045636
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
524 |
539 |
N/A |
INTRINSIC |
|
coiled coil region
|
876 |
938 |
N/A |
INTRINSIC |
|
SCOP:d1eq1a_
|
1021 |
1156 |
3e-7 |
SMART |
|
low complexity region
|
1195 |
1209 |
N/A |
INTRINSIC |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000123703
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000127665
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000131965
|
| SMART Domains |
Protein: ENSMUSP00000121605
Gene: ENSMUSG00000045636
| Domain | Start | End | E-Value | Type |
|---|
|
coiled coil region
|
9 |
67 |
N/A |
INTRINSIC |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000152188
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000155626
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000142936
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000155174
|
| Coding Region Coverage |
- 1x: 99.0%
- 3x: 98.1%
- 10x: 95.9%
- 20x: 91.2%
|
| Validation Efficiency |
97% (89/92) |
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a protein which contains a C-terminal domain able to interact with the angiotension II (AT2) receptor and a large coiled-coil region allowing dimerization. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. One of the transcript variants has been shown to encode a mitochondrial protein that acts as a tumor suppressor and partcipates in AT2 signaling pathways. Other variants may encode nuclear or transmembrane proteins but it has not been determined whether they also participate in AT2 signaling pathways. [provided by RefSeq, Jul 2008]
PHENOTYPE: Mice homozygous for a gene trap allele exhibit spontaneous heart hypertrophy and SLE-like lymphoproliferative disease. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 87 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| A230072I06Rik |
C |
T |
8: 12,329,899 (GRCm39) |
S118L |
unknown |
Het |
| Adprs |
A |
G |
4: 126,211,947 (GRCm39) |
Y122H |
probably damaging |
Het |
| Ankrd52 |
T |
C |
10: 128,222,007 (GRCm39) |
S544P |
probably benign |
Het |
| Aopep |
A |
G |
13: 63,338,298 (GRCm39) |
N558S |
probably benign |
Het |
| Arhgef7 |
A |
G |
8: 11,850,503 (GRCm39) |
E111G |
probably damaging |
Het |
| Atp11a |
A |
G |
8: 12,896,054 (GRCm39) |
M755V |
probably benign |
Het |
| Atp2a2 |
A |
G |
5: 122,629,778 (GRCm39) |
I97T |
probably damaging |
Het |
| Bmp3 |
G |
A |
5: 99,027,768 (GRCm39) |
D463N |
possibly damaging |
Het |
| Cacna2d4 |
T |
C |
6: 119,255,230 (GRCm39) |
|
probably benign |
Het |
| Ccdc28a |
G |
A |
10: 18,106,188 (GRCm39) |
S46F |
possibly damaging |
Het |
| Ccdc40 |
G |
A |
11: 119,155,125 (GRCm39) |
G1122S |
probably benign |
Het |
| Cenpw |
T |
G |
10: 30,076,455 (GRCm39) |
T8P |
probably benign |
Het |
| Cfap44 |
G |
C |
16: 44,253,785 (GRCm39) |
G893R |
possibly damaging |
Het |
| Cimap3 |
A |
T |
3: 105,906,886 (GRCm39) |
M171K |
possibly damaging |
Het |
| Cops7a |
A |
T |
6: 124,938,323 (GRCm39) |
C110S |
probably damaging |
Het |
| Cstl1 |
A |
G |
2: 148,597,245 (GRCm39) |
N134S |
probably damaging |
Het |
| Cyp2s1 |
G |
T |
7: 25,511,114 (GRCm39) |
|
probably null |
Het |
| Dio2 |
T |
A |
12: 90,696,617 (GRCm39) |
N124Y |
probably damaging |
Het |
| Ecel1 |
C |
A |
1: 87,082,248 (GRCm39) |
G155V |
possibly damaging |
Het |
| Efr3a |
G |
T |
15: 65,717,830 (GRCm39) |
V337F |
possibly damaging |
Het |
| Eva1b |
A |
C |
4: 126,043,446 (GRCm39) |
H162P |
probably damaging |
Het |
| Exoc5 |
C |
T |
14: 49,273,493 (GRCm39) |
E301K |
probably damaging |
Het |
| F13b |
G |
A |
1: 139,435,941 (GRCm39) |
S249N |
probably damaging |
Het |
| Fam120b |
C |
T |
17: 15,646,446 (GRCm39) |
|
probably benign |
Het |
| Gbf1 |
T |
C |
19: 46,250,231 (GRCm39) |
L396S |
probably damaging |
Het |
| Gck |
T |
A |
11: 5,859,139 (GRCm39) |
K143* |
probably null |
Het |
| Gck |
C |
A |
11: 5,860,370 (GRCm39) |
V91L |
probably damaging |
Het |
| Glt8d2 |
T |
C |
10: 82,496,644 (GRCm39) |
N138S |
probably damaging |
Het |
| Gm4884 |
T |
C |
7: 40,692,387 (GRCm39) |
F119L |
probably benign |
Het |
| Igsf11 |
T |
C |
16: 38,829,240 (GRCm39) |
S45P |
probably damaging |
Het |
| Iho1 |
T |
C |
9: 108,289,695 (GRCm39) |
T176A |
probably damaging |
Het |
| Il10 |
G |
A |
1: 130,950,271 (GRCm39) |
V142M |
probably damaging |
Het |
| Insc |
A |
T |
7: 114,368,237 (GRCm39) |
H9L |
probably damaging |
Het |
| Iqsec1 |
G |
T |
6: 90,786,740 (GRCm39) |
|
probably benign |
Het |
| Katnb1 |
A |
G |
8: 95,825,050 (GRCm39) |
S611G |
possibly damaging |
Het |
| Kcnb1 |
A |
G |
2: 166,947,459 (GRCm39) |
I463T |
possibly damaging |
Het |
| Lao1 |
A |
G |
4: 118,821,399 (GRCm39) |
N90S |
probably benign |
Het |
| Med16 |
T |
A |
10: 79,732,635 (GRCm39) |
M710L |
probably benign |
Het |
| Mroh2a |
G |
C |
1: 88,185,524 (GRCm39) |
E1510D |
probably damaging |
Het |
| Mybpc3 |
A |
G |
2: 90,950,682 (GRCm39) |
|
probably benign |
Het |
| Ndor1 |
C |
T |
2: 25,138,366 (GRCm39) |
V405M |
possibly damaging |
Het |
| Nell2 |
A |
G |
15: 95,330,782 (GRCm39) |
V213A |
probably benign |
Het |
| Nme8 |
T |
C |
13: 19,862,018 (GRCm39) |
I204V |
probably benign |
Het |
| Nup133 |
A |
T |
8: 124,656,082 (GRCm39) |
N466K |
probably benign |
Het |
| Nxt1 |
A |
G |
2: 148,517,390 (GRCm39) |
T44A |
probably benign |
Het |
| Or14c46 |
T |
C |
7: 85,918,187 (GRCm39) |
E270G |
probably benign |
Het |
| Or2ag15 |
A |
T |
7: 106,340,832 (GRCm39) |
I103N |
probably benign |
Het |
| Or2y12 |
C |
T |
11: 49,426,401 (GRCm39) |
L130F |
probably benign |
Het |
| Or4e1 |
T |
C |
14: 52,700,669 (GRCm39) |
T239A |
probably damaging |
Het |
| Or4f7 |
A |
T |
2: 111,644,699 (GRCm39) |
I124K |
possibly damaging |
Het |
| Or7e168 |
C |
T |
9: 19,720,165 (GRCm39) |
L184F |
probably damaging |
Het |
| Pced1a |
T |
C |
2: 130,263,827 (GRCm39) |
K275R |
probably benign |
Het |
| Pdcd11 |
A |
G |
19: 47,099,398 (GRCm39) |
|
probably null |
Het |
| Phldb2 |
A |
C |
16: 45,591,029 (GRCm39) |
|
probably benign |
Het |
| Piwil1 |
C |
A |
5: 128,824,387 (GRCm39) |
S490Y |
probably damaging |
Het |
| Plekhh3 |
T |
C |
11: 101,054,501 (GRCm39) |
|
probably benign |
Het |
| Ppargc1b |
A |
T |
18: 61,449,034 (GRCm39) |
|
probably benign |
Het |
| Psg19 |
C |
T |
7: 18,530,942 (GRCm39) |
V71I |
possibly damaging |
Het |
| Ptk6 |
T |
C |
2: 180,838,724 (GRCm39) |
|
probably benign |
Het |
| Pus7 |
A |
G |
5: 23,983,090 (GRCm39) |
S126P |
probably damaging |
Het |
| Rab6b |
T |
A |
9: 103,017,576 (GRCm39) |
|
probably null |
Het |
| Ranbp3 |
G |
A |
17: 57,016,272 (GRCm39) |
R347Q |
possibly damaging |
Het |
| Sanbr |
A |
T |
11: 23,570,214 (GRCm39) |
|
probably benign |
Het |
| Sbf1 |
A |
T |
15: 89,186,701 (GRCm39) |
L866Q |
probably damaging |
Het |
| Slc25a34 |
A |
G |
4: 141,349,663 (GRCm39) |
V164A |
possibly damaging |
Het |
| Smg1 |
A |
G |
7: 117,751,898 (GRCm39) |
|
probably null |
Het |
| Spin1 |
G |
T |
13: 51,303,048 (GRCm39) |
V214L |
probably benign |
Het |
| Spmip2 |
A |
T |
3: 79,313,142 (GRCm39) |
Y72F |
probably damaging |
Het |
| Sptbn1 |
T |
C |
11: 30,092,289 (GRCm39) |
N492S |
probably benign |
Het |
| Stk-ps2 |
A |
G |
1: 46,068,955 (GRCm39) |
|
noncoding transcript |
Het |
| Taar7f |
T |
C |
10: 23,926,312 (GRCm39) |
I302T |
probably benign |
Het |
| Tdrd1 |
C |
A |
19: 56,831,630 (GRCm39) |
H340Q |
probably benign |
Het |
| Thumpd3 |
A |
G |
6: 113,044,762 (GRCm39) |
D498G |
probably benign |
Het |
| Tpgs2 |
A |
G |
18: 25,282,242 (GRCm39) |
L103P |
probably damaging |
Het |
| Trip10 |
A |
G |
17: 57,568,633 (GRCm39) |
|
probably null |
Het |
| Trip6 |
A |
T |
5: 137,310,436 (GRCm39) |
H269Q |
probably benign |
Het |
| Trmt12 |
T |
C |
15: 58,744,743 (GRCm39) |
V47A |
possibly damaging |
Het |
| Trpm7 |
A |
T |
2: 126,654,691 (GRCm39) |
S1416T |
probably benign |
Het |
| Tsks |
G |
A |
7: 44,603,883 (GRCm39) |
A438T |
probably benign |
Het |
| Ttn |
T |
C |
2: 76,727,630 (GRCm39) |
|
probably benign |
Het |
| Twf2 |
G |
A |
9: 106,090,155 (GRCm39) |
V136M |
possibly damaging |
Het |
| Uty |
A |
C |
Y: 1,197,223 (GRCm39) |
Y115D |
probably damaging |
Het |
| Vcan |
A |
G |
13: 89,839,380 (GRCm39) |
S2055P |
probably damaging |
Het |
| Yes1 |
A |
G |
5: 32,842,039 (GRCm39) |
Q521R |
possibly damaging |
Het |
| Zfp114 |
A |
T |
7: 23,880,685 (GRCm39) |
T344S |
possibly damaging |
Het |
| Zfp661 |
A |
T |
2: 127,420,532 (GRCm39) |
V89D |
possibly damaging |
Het |
| Zfp91 |
A |
T |
19: 12,747,834 (GRCm39) |
Y430N |
probably damaging |
Het |
|
| Other mutations in Mtus1 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00708:Mtus1
|
APN |
8 |
41,537,386 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01377:Mtus1
|
APN |
8 |
41,536,172 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
IGL01472:Mtus1
|
APN |
8 |
41,455,449 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL01995:Mtus1
|
APN |
8 |
41,537,457 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02027:Mtus1
|
APN |
8 |
41,446,638 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02381:Mtus1
|
APN |
8 |
41,536,156 (GRCm39) |
missense |
probably benign |
0.05 |
|
IGL02571:Mtus1
|
APN |
8 |
41,536,519 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
IGL02936:Mtus1
|
APN |
8 |
41,452,554 (GRCm39) |
missense |
possibly damaging |
0.79 |
|
R0116:Mtus1
|
UTSW |
8 |
41,451,514 (GRCm39) |
unclassified |
probably benign |
|
|
R0178:Mtus1
|
UTSW |
8 |
41,455,398 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R0179:Mtus1
|
UTSW |
8 |
41,455,398 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R0220:Mtus1
|
UTSW |
8 |
41,447,609 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0324:Mtus1
|
UTSW |
8 |
41,537,432 (GRCm39) |
missense |
probably benign |
|
|
R0355:Mtus1
|
UTSW |
8 |
41,535,965 (GRCm39) |
missense |
probably benign |
0.02 |
|
R0357:Mtus1
|
UTSW |
8 |
41,536,563 (GRCm39) |
missense |
possibly damaging |
0.71 |
|
R0464:Mtus1
|
UTSW |
8 |
41,455,511 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R0681:Mtus1
|
UTSW |
8 |
41,446,554 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1016:Mtus1
|
UTSW |
8 |
41,503,063 (GRCm39) |
missense |
probably benign |
0.43 |
|
R1570:Mtus1
|
UTSW |
8 |
41,529,278 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1579:Mtus1
|
UTSW |
8 |
41,535,895 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1607:Mtus1
|
UTSW |
8 |
41,468,446 (GRCm39) |
missense |
possibly damaging |
0.58 |
|
R1869:Mtus1
|
UTSW |
8 |
41,529,267 (GRCm39) |
critical splice donor site |
probably null |
|
|
R1888:Mtus1
|
UTSW |
8 |
41,537,362 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R1888:Mtus1
|
UTSW |
8 |
41,537,362 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R1891:Mtus1
|
UTSW |
8 |
41,537,362 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R1894:Mtus1
|
UTSW |
8 |
41,537,362 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R2063:Mtus1
|
UTSW |
8 |
41,535,745 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2111:Mtus1
|
UTSW |
8 |
41,475,608 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2112:Mtus1
|
UTSW |
8 |
41,475,608 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2224:Mtus1
|
UTSW |
8 |
41,535,812 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2226:Mtus1
|
UTSW |
8 |
41,535,812 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2227:Mtus1
|
UTSW |
8 |
41,535,812 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2516:Mtus1
|
UTSW |
8 |
41,535,776 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3414:Mtus1
|
UTSW |
8 |
41,501,100 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3899:Mtus1
|
UTSW |
8 |
41,536,166 (GRCm39) |
missense |
probably benign |
|
|
R4096:Mtus1
|
UTSW |
8 |
41,537,284 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4831:Mtus1
|
UTSW |
8 |
41,536,189 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4850:Mtus1
|
UTSW |
8 |
41,537,507 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
R4916:Mtus1
|
UTSW |
8 |
41,453,838 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4940:Mtus1
|
UTSW |
8 |
41,494,515 (GRCm39) |
missense |
possibly damaging |
0.52 |
|
R4988:Mtus1
|
UTSW |
8 |
41,537,578 (GRCm39) |
missense |
probably benign |
0.05 |
|
R5133:Mtus1
|
UTSW |
8 |
41,536,229 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5468:Mtus1
|
UTSW |
8 |
41,537,615 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5598:Mtus1
|
UTSW |
8 |
41,475,592 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5782:Mtus1
|
UTSW |
8 |
41,535,764 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5860:Mtus1
|
UTSW |
8 |
41,529,303 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5900:Mtus1
|
UTSW |
8 |
41,536,534 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R5943:Mtus1
|
UTSW |
8 |
41,537,302 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6019:Mtus1
|
UTSW |
8 |
41,536,077 (GRCm39) |
missense |
probably benign |
0.33 |
|
R6125:Mtus1
|
UTSW |
8 |
41,537,576 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6197:Mtus1
|
UTSW |
8 |
41,537,074 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R6488:Mtus1
|
UTSW |
8 |
41,494,545 (GRCm39) |
missense |
possibly damaging |
0.52 |
|
R6869:Mtus1
|
UTSW |
8 |
41,535,691 (GRCm39) |
missense |
possibly damaging |
0.71 |
|
R7117:Mtus1
|
UTSW |
8 |
41,536,621 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R7126:Mtus1
|
UTSW |
8 |
41,468,439 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R7213:Mtus1
|
UTSW |
8 |
41,537,524 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7308:Mtus1
|
UTSW |
8 |
41,535,965 (GRCm39) |
missense |
probably benign |
0.02 |
|
R7424:Mtus1
|
UTSW |
8 |
41,475,443 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7481:Mtus1
|
UTSW |
8 |
41,537,652 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7485:Mtus1
|
UTSW |
8 |
41,537,590 (GRCm39) |
missense |
probably benign |
0.37 |
|
R7660:Mtus1
|
UTSW |
8 |
41,469,248 (GRCm39) |
missense |
probably benign |
|
|
R7699:Mtus1
|
UTSW |
8 |
41,537,006 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R7700:Mtus1
|
UTSW |
8 |
41,537,006 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R7709:Mtus1
|
UTSW |
8 |
41,507,687 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
R7791:Mtus1
|
UTSW |
8 |
41,536,417 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
R8196:Mtus1
|
UTSW |
8 |
41,509,689 (GRCm39) |
missense |
probably benign |
|
|
R8463:Mtus1
|
UTSW |
8 |
41,536,271 (GRCm39) |
missense |
probably benign |
0.01 |
|
R8724:Mtus1
|
UTSW |
8 |
41,451,500 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9047:Mtus1
|
UTSW |
8 |
41,536,760 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R9092:Mtus1
|
UTSW |
8 |
41,455,475 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9283:Mtus1
|
UTSW |
8 |
41,536,519 (GRCm39) |
missense |
probably benign |
0.02 |
|
R9313:Mtus1
|
UTSW |
8 |
41,535,923 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9329:Mtus1
|
UTSW |
8 |
41,537,239 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9603:Mtus1
|
UTSW |
8 |
41,536,795 (GRCm39) |
missense |
probably benign |
0.04 |
|
R9711:Mtus1
|
UTSW |
8 |
41,536,222 (GRCm39) |
missense |
probably damaging |
0.99 |
|
| Predicted Primers |
PCR Primer
(F):5'- GCTACACAGCAGTTTCCAAGGACTC -3'
(R):5'- GCAGCAAAATGTGCCTCTCTCCTC -3'
Sequencing Primer
(F):5'- AGCAGTTTCCAAGGACTCTTACATC -3'
(R):5'- TGTCAGGGACTACGTACTGC -3'
|
| Posted On |
2013-04-16 |
Incidental Mutation