Mutagenetix > Incidental Mutation

Incidental Mutation 'R1981:Baz2b'

222252

Institutional Source

Beutler Lab

Gene Symbol

Baz2b

Ensembl Gene

ENSMUSG00000026987

Gene Name

bromodomain adjacent to zinc finger domain, 2B

Synonyms

D2Ertd794e, 5830435C13Rik

MMRRC Submission

039993-MU

Accession Numbers

Essential gene?

Possibly non essential (E-score: 0.287) question?

Stock #

R1981 (G1)

Quality Score

225

Status

Validated

Chromosome

Chromosomal Location

59729707-60040183 bp(-) (GRCm39)

Type of Mutation

missense

DNA Base Change (assembly)

A to G at 59754024 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Phenylalanine to Leucine at position 1100 (F1100L)

Ref Sequence

ENSEMBL: ENSMUSP00000108169 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000090925] [ENSMUST00000112550] [ENSMUST00000153136]

AlphaFold

A2AUY4

Predicted Effect

possibly damaging
Transcript: ENSMUST00000090925
AA Change: F1100L

PolyPhen 2 Score 0.953 (Sensitivity: 0.79; Specificity: 0.95)

SMART Domains

Protein: ENSMUSP00000088443
Gene: ENSMUSG00000026987
AA Change: F1100L

Domain	Start	End	E-Value	Type
low complexity region	7	46	N/A	INTRINSIC
low complexity region	82	97	N/A	INTRINSIC
low complexity region	147	162	N/A	INTRINSIC
low complexity region	193	244	N/A	INTRINSIC
low complexity region	291	308	N/A	INTRINSIC
low complexity region	366	385	N/A	INTRINSIC
low complexity region	528	540	N/A	INTRINSIC
low complexity region	554	614	N/A	INTRINSIC
low complexity region	628	637	N/A	INTRINSIC
low complexity region	671	685	N/A	INTRINSIC
Pfam:MBD	690	742	1e-12	PFAM
low complexity region	759	774	N/A	INTRINSIC
coiled coil region	814	975	N/A	INTRINSIC
DDT	1004	1069	1.19e-20	SMART
low complexity region	1199	1212	N/A	INTRINSIC
low complexity region	1213	1247	N/A	INTRINSIC
coiled coil region	1251	1286	N/A	INTRINSIC
low complexity region	1320	1337	N/A	INTRINSIC
low complexity region	1503	1524	N/A	INTRINSIC
low complexity region	1569	1582	N/A	INTRINSIC
low complexity region	1585	1605	N/A	INTRINSIC
Blast:BROMO	1802	1843	7e-18	BLAST
PHD	1888	1934	1.71e-12	SMART
low complexity region	1942	1964	N/A	INTRINSIC
low complexity region	1968	1980	N/A	INTRINSIC
BROMO	2013	2121	3.85e-41	SMART

Predicted Effect

possibly damaging
Transcript: ENSMUST00000112550
AA Change: F1100L

PolyPhen 2 Score 0.953 (Sensitivity: 0.79; Specificity: 0.95)

SMART Domains

Protein: ENSMUSP00000108169
Gene: ENSMUSG00000026987
AA Change: F1100L

Domain	Start	End	E-Value	Type
low complexity region	7	46	N/A	INTRINSIC
low complexity region	82	97	N/A	INTRINSIC
low complexity region	147	162	N/A	INTRINSIC
low complexity region	193	244	N/A	INTRINSIC
low complexity region	291	308	N/A	INTRINSIC
low complexity region	366	385	N/A	INTRINSIC
low complexity region	528	540	N/A	INTRINSIC
low complexity region	554	614	N/A	INTRINSIC
low complexity region	628	637	N/A	INTRINSIC
low complexity region	671	685	N/A	INTRINSIC
Pfam:MBD	690	741	3.4e-13	PFAM
low complexity region	759	774	N/A	INTRINSIC
coiled coil region	814	975	N/A	INTRINSIC
DDT	1004	1069	1.19e-20	SMART
low complexity region	1199	1212	N/A	INTRINSIC
low complexity region	1213	1247	N/A	INTRINSIC
coiled coil region	1251	1286	N/A	INTRINSIC
low complexity region	1320	1337	N/A	INTRINSIC
low complexity region	1503	1524	N/A	INTRINSIC
low complexity region	1569	1582	N/A	INTRINSIC
low complexity region	1585	1605	N/A	INTRINSIC
Pfam:WHIM3	1638	1676	5.1e-14	PFAM
Blast:BROMO	1802	1843	7e-18	BLAST
PHD	1888	1934	1.71e-12	SMART
low complexity region	1942	1964	N/A	INTRINSIC
low complexity region	1968	1980	N/A	INTRINSIC
BROMO	2013	2121	3.85e-41	SMART

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000147476

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000152639

Predicted Effect

probably benign
Transcript: ENSMUST00000153136

SMART Domains

Protein: ENSMUSP00000118981
Gene: ENSMUSG00000026987

Domain	Start	End	E-Value	Type
coiled coil region	48	218	N/A	INTRINSIC
Pfam:DDT	247	296	1.6e-13	PFAM

Meta Mutation Damage Score

0.6240

Coding Region Coverage

1x: 99.2%
3x: 98.5%
10x: 96.9%
20x: 94.6%

Validation Efficiency

99% (80/81)

MGI Phenotype

FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene belongs to the bromodomain gene family. Members of this gene family encode proteins that are integral components of chromatin remodeling complexes. The encoded protein showed strong preference for the activating H3K14Ac mark in a histone peptide screen, suggesting a potential role in transcriptional activation. This gene may be associated with susceptibility to sudden cardiac death (SCD). [provided by RefSeq, Aug 2016]

Allele List at MGI

Other mutations in this stock

Total: 80 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Anks1	T	C	17: 28,204,095 (GRCm39)	V181A	probably damaging	Het
Aqp4	T	C	18: 15,526,608 (GRCm39)	D291G	probably damaging	Het
Atad1	G	T	19: 32,673,210 (GRCm39)	D224E	probably benign	Het
Atp1a3	T	G	7: 24,700,400 (GRCm39)	E33A	probably benign	Het
Car7	C	T	8: 105,275,009 (GRCm39)		probably benign	Het
Casp8	C	A	1: 58,868,121 (GRCm39)		probably null	Het
Cdh23	A	T	10: 60,214,530 (GRCm39)	L1495H	probably damaging	Het
Ceacam9	T	G	7: 16,459,232 (GRCm39)	L177R	probably benign	Het
Col16a1	C	G	4: 129,959,236 (GRCm39)	P346A	unknown	Het
Cyp2c29	A	G	19: 39,296,216 (GRCm39)		probably null	Het
Cyp3a13	T	C	5: 137,910,118 (GRCm39)	S139G	probably damaging	Het
Dapk2	A	G	9: 66,176,180 (GRCm39)	H327R	probably benign	Het
Ddx19b	T	C	8: 111,735,975 (GRCm39)	T357A	possibly damaging	Het
Dnah2	A	G	11: 69,365,151 (GRCm39)	Y1944H	probably damaging	Het
Dnai2	T	A	11: 114,623,755 (GRCm39)	V6E	probably damaging	Het
Eipr1	T	C	12: 28,913,024 (GRCm39)	Y242H	probably damaging	Het
Fam149a	T	G	8: 45,834,778 (GRCm39)	D7A	probably damaging	Het
Fam217a	T	A	13: 35,100,737 (GRCm39)	D140V	probably benign	Het
Fat4	G	A	3: 39,045,813 (GRCm39)	C3944Y	probably damaging	Het
Fezf2	G	T	14: 12,344,405 (GRCm38)	P261T	probably benign	Het
Gcsam	A	T	16: 45,440,337 (GRCm39)	T127S	probably damaging	Het
Git2	C	T	5: 114,887,620 (GRCm39)		probably benign	Het
Gm1527	T	C	3: 28,969,984 (GRCm39)		probably null	Het
Gtf3c1	A	G	7: 125,243,444 (GRCm39)	L1720P	possibly damaging	Het
H2-T9	T	A	17: 36,439,614 (GRCm39)	D122V	probably damaging	Het
Hat1	A	G	2: 71,220,321 (GRCm39)	T28A	probably benign	Het
Igf2r	G	A	17: 12,952,790 (GRCm39)	Q219*	probably null	Het
Impdh1	T	A	6: 29,206,450 (GRCm39)	D129V	possibly damaging	Het
Kcnh8	GAGACCAACGAGCAGCTGATGCTTCAGA	GAGA	17: 53,032,934 (GRCm39)	74	probably benign	Het
Ltbp3	A	G	19: 5,808,107 (GRCm39)	Q1250R	probably benign	Het
Mansc4	T	A	6: 146,977,173 (GRCm39)	I148F	probably benign	Het
Mast2	T	C	4: 116,172,037 (GRCm39)	Y569C	probably damaging	Het
Mcoln3	A	T	3: 145,846,345 (GRCm39)	K552*	probably null	Het
Mctp2	T	C	7: 71,814,446 (GRCm39)	Q601R	probably benign	Het
Mei1	A	G	15: 81,987,513 (GRCm39)	N859S	probably benign	Het
Myo19	A	T	11: 84,782,996 (GRCm39)	Q170L	possibly damaging	Het
Myo1h	T	C	5: 114,491,898 (GRCm39)	F676S	probably damaging	Het
Myo9a	A	G	9: 59,801,429 (GRCm39)	T1876A	probably benign	Het
Nav3	G	T	10: 109,554,951 (GRCm39)		probably benign	Het
Ndor1	T	C	2: 25,145,236 (GRCm39)	Y43C	probably damaging	Het
Nlrp1a	A	G	11: 70,989,764 (GRCm39)	V1102A	probably damaging	Het
Nmnat3	T	C	9: 98,292,352 (GRCm39)	I199T	possibly damaging	Het
Nsun7	T	C	5: 66,418,557 (GRCm39)	S96P	probably damaging	Het
Ntng1	A	G	3: 109,842,326 (GRCm39)	V149A	possibly damaging	Het
Oas3	T	C	5: 120,899,900 (GRCm39)		probably benign	Het
Or10v9	T	G	19: 11,832,371 (GRCm39)	Q315H	possibly damaging	Het
Or4k47	T	A	2: 111,451,586 (GRCm39)	I278F	probably benign	Het
Or5bw2	A	G	7: 6,573,557 (GRCm39)	D189G	probably benign	Het
Or6z7	T	C	7: 6,483,931 (GRCm39)	M75V	probably benign	Het
Or8b3	T	C	9: 38,315,031 (GRCm39)	L287P	probably damaging	Het
Or8k53	A	T	2: 86,177,486 (GRCm39)	I208N	possibly damaging	Het
Pax2	G	A	19: 44,806,904 (GRCm39)	D301N	probably damaging	Het
Pcsk4	T	A	10: 80,161,613 (GRCm39)	E176V	probably damaging	Het
Pkhd1	G	A	1: 20,187,284 (GRCm39)	P3675S	probably benign	Het
Plekho2	A	T	9: 65,465,974 (GRCm39)	L138Q	probably damaging	Het
Ppp4r3c1	A	T	X: 88,975,051 (GRCm39)	V382E	probably damaging	Het
Prkcsh	A	G	9: 21,924,164 (GRCm39)	D458G	probably damaging	Het
Prr11	T	A	11: 86,994,116 (GRCm39)	D100V	probably damaging	Het
Qars1	A	G	9: 108,392,227 (GRCm39)	N136D	probably damaging	Het
Rbm15b	A	G	9: 106,758,822 (GRCm39)		probably benign	Het
Rel	C	T	11: 23,692,761 (GRCm39)	G424D	probably benign	Het
Rsrc1	A	G	3: 67,257,338 (GRCm39)	D250G	probably benign	Het
Samt3	A	C	X: 85,090,740 (GRCm39)	M211L	probably benign	Het
Scn2a	C	A	2: 65,520,514 (GRCm39)	N503K	probably damaging	Het
Sh2d6	G	A	6: 72,494,527 (GRCm39)		probably benign	Het
Smg8	T	C	11: 86,976,157 (GRCm39)	T475A	probably benign	Het
Ssxb10	A	G	X: 8,197,258 (GRCm39)	D77G	probably benign	Het
Tbx20	T	A	9: 24,682,209 (GRCm39)	K48N	possibly damaging	Het
Tead1	C	A	7: 112,490,952 (GRCm39)	D231E	probably benign	Het
Ticam1	C	T	17: 56,578,555 (GRCm39)	R180H	probably damaging	Het
Tjp1	A	T	7: 64,962,603 (GRCm39)	F1111L	probably damaging	Het
Tlr11	T	A	14: 50,599,445 (GRCm39)	I477K	possibly damaging	Het
Ttc13	A	G	8: 125,440,926 (GRCm39)		probably null	Het
Ttc17	T	C	2: 94,157,049 (GRCm39)	N411S	probably benign	Het
Usp15	T	A	10: 122,960,946 (GRCm39)		probably benign	Het
Usp18	A	G	6: 121,229,476 (GRCm39)	K32E	probably benign	Het
Vmn1r12	A	T	6: 57,136,646 (GRCm39)	M248L	probably benign	Het
Zbtb14	C	A	17: 69,695,497 (GRCm39)	F398L	probably damaging	Het
Zfp930	T	A	8: 69,680,824 (GRCm39)	L172H	probably damaging	Het
Zfp976	G	A	7: 42,263,046 (GRCm39)	H264Y	probably damaging	Het

Other mutations in Baz2b

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00430:Baz2b	APN	2	59,743,139 (GRCm39)	missense	probably benign	0.02
IGL00476:Baz2b	APN	2	59,744,083 (GRCm39)	missense	probably benign	0.06
IGL00489:Baz2b	APN	2	59,788,019 (GRCm39)	nonsense	probably null
IGL00514:Baz2b	APN	2	59,792,821 (GRCm39)	missense	probably benign	0.11
IGL00678:Baz2b	APN	2	59,836,527 (GRCm39)	missense	unknown
IGL01348:Baz2b	APN	2	59,764,031 (GRCm39)	missense	possibly damaging	0.95
IGL01354:Baz2b	APN	2	59,799,233 (GRCm39)	missense	probably benign	0.18
IGL01924:Baz2b	APN	2	59,765,615 (GRCm39)	missense	probably damaging	1.00
IGL02125:Baz2b	APN	2	59,798,984 (GRCm39)	missense	probably benign	0.12
IGL02314:Baz2b	APN	2	59,792,571 (GRCm39)	missense	probably benign
IGL02370:Baz2b	APN	2	59,753,933 (GRCm39)	missense	possibly damaging	0.77
IGL02473:Baz2b	APN	2	59,790,407 (GRCm39)	missense	probably benign	0.40
IGL02499:Baz2b	APN	2	59,731,840 (GRCm39)	missense	possibly damaging	0.60
IGL02609:Baz2b	APN	2	59,747,713 (GRCm39)	missense	possibly damaging	0.77
IGL02705:Baz2b	APN	2	59,778,604 (GRCm39)	missense	possibly damaging	0.92
IGL02711:Baz2b	APN	2	59,747,849 (GRCm39)	unclassified	probably benign
IGL02716:Baz2b	APN	2	59,792,868 (GRCm39)	missense	possibly damaging	0.53
IGL02724:Baz2b	APN	2	59,807,718 (GRCm39)	missense	possibly damaging	0.70
IGL02750:Baz2b	APN	2	59,799,002 (GRCm39)	missense	possibly damaging	0.73
IGL02869:Baz2b	APN	2	59,807,872 (GRCm39)	missense	probably benign	0.00
IGL02886:Baz2b	APN	2	59,788,087 (GRCm39)	splice site	probably null
IGL02892:Baz2b	APN	2	59,731,080 (GRCm39)	missense	probably damaging	1.00
IGL03132:Baz2b	APN	2	59,738,097 (GRCm39)	splice site	probably benign
IGL03183:Baz2b	APN	2	59,733,640 (GRCm39)	missense	probably benign	0.10
IGL03197:Baz2b	APN	2	59,731,898 (GRCm39)	missense	possibly damaging	0.74
R0054:Baz2b	UTSW	2	59,762,510 (GRCm39)	missense	probably damaging	1.00
R0054:Baz2b	UTSW	2	59,762,510 (GRCm39)	missense	probably damaging	1.00
R0122:Baz2b	UTSW	2	59,743,963 (GRCm39)	splice site	probably null
R0136:Baz2b	UTSW	2	59,732,298 (GRCm39)	missense	probably benign	0.22
R0144:Baz2b	UTSW	2	59,737,839 (GRCm39)	missense	probably damaging	0.98
R0403:Baz2b	UTSW	2	59,799,721 (GRCm39)	missense	possibly damaging	0.70
R0498:Baz2b	UTSW	2	59,732,340 (GRCm39)	unclassified	probably benign
R0528:Baz2b	UTSW	2	59,767,083 (GRCm39)	missense	probably damaging	1.00
R1025:Baz2b	UTSW	2	59,792,826 (GRCm39)	missense	probably benign	0.06
R1470:Baz2b	UTSW	2	59,808,890 (GRCm39)	missense	possibly damaging	0.53
R1470:Baz2b	UTSW	2	59,808,890 (GRCm39)	missense	possibly damaging	0.53
R1510:Baz2b	UTSW	2	59,752,553 (GRCm39)	missense	probably damaging	1.00
R1511:Baz2b	UTSW	2	59,792,368 (GRCm39)	missense	probably benign	0.12
R1514:Baz2b	UTSW	2	59,792,670 (GRCm39)	missense	probably benign	0.13
R1519:Baz2b	UTSW	2	59,778,598 (GRCm39)	missense	possibly damaging	0.50
R1523:Baz2b	UTSW	2	59,798,981 (GRCm39)	missense	possibly damaging	0.47
R1630:Baz2b	UTSW	2	59,836,474 (GRCm39)	missense	unknown
R1641:Baz2b	UTSW	2	59,743,234 (GRCm39)	missense	probably damaging	0.99
R1674:Baz2b	UTSW	2	59,743,336 (GRCm39)	missense	possibly damaging	0.53
R1778:Baz2b	UTSW	2	59,836,480 (GRCm39)	missense	unknown
R1826:Baz2b	UTSW	2	59,799,077 (GRCm39)	missense	probably benign	0.12
R1835:Baz2b	UTSW	2	59,732,163 (GRCm39)	missense	probably benign	0.02
R1954:Baz2b	UTSW	2	59,799,087 (GRCm39)	missense	probably benign	0.12
R2029:Baz2b	UTSW	2	59,743,067 (GRCm39)	unclassified	probably benign
R2567:Baz2b	UTSW	2	59,744,255 (GRCm39)	missense	possibly damaging	0.82
R2842:Baz2b	UTSW	2	59,743,348 (GRCm39)	missense	probably benign	0.27
R2848:Baz2b	UTSW	2	59,755,010 (GRCm39)	missense	possibly damaging	0.64
R3809:Baz2b	UTSW	2	59,799,240 (GRCm39)	missense	probably benign	0.12
R3935:Baz2b	UTSW	2	59,743,105 (GRCm39)	missense	possibly damaging	0.81
R3936:Baz2b	UTSW	2	59,743,105 (GRCm39)	missense	possibly damaging	0.81
R4072:Baz2b	UTSW	2	59,742,917 (GRCm39)	splice site	probably null
R4182:Baz2b	UTSW	2	59,928,801 (GRCm39)	intron	probably benign
R4255:Baz2b	UTSW	2	59,750,916 (GRCm39)	unclassified	probably benign
R4359:Baz2b	UTSW	2	59,731,957 (GRCm39)	missense	possibly damaging	0.87
R4716:Baz2b	UTSW	2	59,799,599 (GRCm39)	missense	probably benign	0.06
R4743:Baz2b	UTSW	2	59,744,255 (GRCm39)	missense	probably benign	0.01
R4772:Baz2b	UTSW	2	59,788,795 (GRCm39)	missense	probably damaging	0.96
R4858:Baz2b	UTSW	2	59,738,087 (GRCm39)	missense	probably benign
R4868:Baz2b	UTSW	2	59,755,226 (GRCm39)	missense	possibly damaging	0.65
R4872:Baz2b	UTSW	2	59,773,103 (GRCm39)	splice site	probably null
R4889:Baz2b	UTSW	2	59,767,070 (GRCm39)	missense	probably damaging	1.00
R4890:Baz2b	UTSW	2	59,756,383 (GRCm39)	missense	probably damaging	0.99
R4914:Baz2b	UTSW	2	59,744,387 (GRCm39)	missense	possibly damaging	0.70
R4915:Baz2b	UTSW	2	59,744,387 (GRCm39)	missense	possibly damaging	0.70
R4918:Baz2b	UTSW	2	59,744,387 (GRCm39)	missense	possibly damaging	0.70
R5027:Baz2b	UTSW	2	59,928,988 (GRCm39)	intron	probably benign
R5031:Baz2b	UTSW	2	59,743,151 (GRCm39)	missense	probably benign	0.00
R5082:Baz2b	UTSW	2	59,731,835 (GRCm39)	nonsense	probably null
R5133:Baz2b	UTSW	2	59,792,368 (GRCm39)	missense	probably benign	0.12
R5276:Baz2b	UTSW	2	59,792,958 (GRCm39)	missense	probably benign	0.40
R5279:Baz2b	UTSW	2	59,762,496 (GRCm39)	missense	probably damaging	1.00
R5294:Baz2b	UTSW	2	59,808,946 (GRCm39)	missense	probably benign	0.11
R5447:Baz2b	UTSW	2	59,744,332 (GRCm39)	missense	probably damaging	0.99
R5903:Baz2b	UTSW	2	59,790,233 (GRCm39)	missense	probably damaging	0.99
R5910:Baz2b	UTSW	2	59,807,770 (GRCm39)	missense	possibly damaging	0.88
R6140:Baz2b	UTSW	2	59,742,871 (GRCm39)	missense	probably damaging	0.99
R6195:Baz2b	UTSW	2	59,737,855 (GRCm39)	missense	possibly damaging	0.89
R6199:Baz2b	UTSW	2	59,809,019 (GRCm39)	missense	probably benign	0.00
R6208:Baz2b	UTSW	2	59,755,150 (GRCm39)	missense	probably damaging	1.00
R6233:Baz2b	UTSW	2	59,737,855 (GRCm39)	missense	possibly damaging	0.89
R6276:Baz2b	UTSW	2	59,778,567 (GRCm39)	missense	probably damaging	1.00
R6324:Baz2b	UTSW	2	59,737,292 (GRCm39)	missense	probably damaging	1.00
R6490:Baz2b	UTSW	2	59,732,073 (GRCm39)	missense	probably damaging	1.00
R6578:Baz2b	UTSW	2	59,799,623 (GRCm39)	missense	possibly damaging	0.47
R6720:Baz2b	UTSW	2	59,755,234 (GRCm39)	missense	probably damaging	1.00
R6760:Baz2b	UTSW	2	59,792,776 (GRCm39)	missense	probably benign	0.40
R6836:Baz2b	UTSW	2	59,747,769 (GRCm39)	missense	probably damaging	1.00
R6859:Baz2b	UTSW	2	59,731,874 (GRCm39)	missense	probably benign	0.01
R6880:Baz2b	UTSW	2	59,743,283 (GRCm39)	missense	probably damaging	0.99
R6916:Baz2b	UTSW	2	59,799,120 (GRCm39)	missense	probably benign
R6978:Baz2b	UTSW	2	59,738,059 (GRCm39)	missense	possibly damaging	0.84
R7037:Baz2b	UTSW	2	59,764,014 (GRCm39)	critical splice donor site	probably null
R7112:Baz2b	UTSW	2	59,792,528 (GRCm39)	missense	possibly damaging	0.53
R7117:Baz2b	UTSW	2	59,742,841 (GRCm39)	missense
R7198:Baz2b	UTSW	2	59,792,550 (GRCm39)	missense	probably benign	0.00
R7270:Baz2b	UTSW	2	59,792,836 (GRCm39)	missense	possibly damaging	0.96
R7282:Baz2b	UTSW	2	59,750,781 (GRCm39)	missense	probably benign	0.17
R7464:Baz2b	UTSW	2	59,807,792 (GRCm39)	missense	possibly damaging	0.53
R7609:Baz2b	UTSW	2	59,792,817 (GRCm39)	missense	probably benign	0.40
R7703:Baz2b	UTSW	2	59,747,769 (GRCm39)	missense	probably damaging	1.00
R7850:Baz2b	UTSW	2	59,767,060 (GRCm39)	missense	probably damaging	0.98
R7851:Baz2b	UTSW	2	59,767,060 (GRCm39)	missense	probably damaging	0.98
R7988:Baz2b	UTSW	2	59,792,485 (GRCm39)	missense	possibly damaging	0.53
R8079:Baz2b	UTSW	2	59,731,112 (GRCm39)	missense	probably damaging	1.00
R8084:Baz2b	UTSW	2	59,792,580 (GRCm39)	missense	probably benign
R8343:Baz2b	UTSW	2	59,731,858 (GRCm39)	missense	probably damaging	1.00
R8348:Baz2b	UTSW	2	59,742,137 (GRCm39)	missense
R8438:Baz2b	UTSW	2	59,747,828 (GRCm39)	nonsense	probably null
R8448:Baz2b	UTSW	2	59,742,137 (GRCm39)	missense
R8511:Baz2b	UTSW	2	59,732,158 (GRCm39)	missense	probably benign
R8893:Baz2b	UTSW	2	59,755,149 (GRCm39)	missense	probably damaging	0.96
R8947:Baz2b	UTSW	2	59,778,583 (GRCm39)	missense	probably benign	0.06
R8998:Baz2b	UTSW	2	59,799,608 (GRCm39)	missense	probably benign	0.02
R9241:Baz2b	UTSW	2	59,743,993 (GRCm39)	missense	probably benign	0.01
R9245:Baz2b	UTSW	2	59,743,331 (GRCm39)	missense	probably benign
R9577:Baz2b	UTSW	2	59,809,031 (GRCm39)	missense	probably benign	0.06
R9581:Baz2b	UTSW	2	59,799,300 (GRCm39)	missense	probably benign
R9601:Baz2b	UTSW	2	59,731,847 (GRCm39)	missense	possibly damaging	0.66
R9613:Baz2b	UTSW	2	59,731,824 (GRCm39)	missense	probably benign	0.09
R9639:Baz2b	UTSW	2	59,731,828 (GRCm39)	missense	probably benign	0.01
X0011:Baz2b	UTSW	2	59,807,705 (GRCm39)	missense	possibly damaging	0.53
X0053:Baz2b	UTSW	2	59,731,019 (GRCm39)	missense	probably damaging	1.00
X0064:Baz2b	UTSW	2	59,799,626 (GRCm39)	missense	probably benign
Z1088:Baz2b	UTSW	2	59,790,359 (GRCm39)	missense	probably damaging	1.00
Z1177:Baz2b	UTSW	2	59,807,864 (GRCm39)	missense	probably benign	0.01
Z1188:Baz2b	UTSW	2	59,807,749 (GRCm39)	missense	probably benign

Predicted Primers

PCR Primer
(F):5'- GCTCTTCAAAACAGGAACGAGC -3'
(R):5'- GCTTAACAAGGGCACAGAAC -3'

Sequencing Primer
(F):5'- GGAACGAGCTCACTTACCTC -3'
(R):5'- TCCACTCCAAATCTGTGATAAAGTC -3'

Posted On

2014-08-25