Incidental Mutation 'R2016:Kif13a'
| ID |
223085 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Kif13a
|
| Ensembl Gene |
ENSMUSG00000021375 |
| Gene Name |
kinesin family member 13A |
| Synonyms |
4930505I07Rik, N-3 kinesin |
| MMRRC Submission |
040025-MU
|
| Accession Numbers |
|
| Essential gene? |
Possibly non essential
(E-score: 0.264)
|
| Stock # |
R2016 (G1)
|
| Quality Score |
225 |
|
Status
|
Not validated
|
| Chromosome |
13 |
| Chromosomal Location |
46902563-47083343 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to C
at 46964275 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Aspartic acid to Glycine
at position 475
(D475G)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000055304
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000056978]
[ENSMUST00000225591]
|
| AlphaFold |
no structure available at present |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000056978
AA Change: D475G
PolyPhen 2
Score 0.134 (Sensitivity: 0.92; Specificity: 0.86)
|
| SMART Domains |
Protein: ENSMUSP00000055304
Gene: ENSMUSG00000021375
AA Change: D475G
| Domain | Start | End | E-Value | Type |
|---|
|
KISc
|
3 |
360 |
2.69e-175 |
SMART |
|
low complexity region
|
368 |
381 |
N/A |
INTRINSIC |
|
low complexity region
|
391 |
406 |
N/A |
INTRINSIC |
|
FHA
|
469 |
519 |
7.16e-2 |
SMART |
|
coiled coil region
|
605 |
639 |
N/A |
INTRINSIC |
|
coiled coil region
|
664 |
704 |
N/A |
INTRINSIC |
|
Pfam:KIF1B
|
748 |
792 |
1.7e-19 |
PFAM |
|
low complexity region
|
840 |
854 |
N/A |
INTRINSIC |
|
low complexity region
|
903 |
915 |
N/A |
INTRINSIC |
|
Pfam:DUF3694
|
1003 |
1270 |
2.2e-39 |
PFAM |
|
low complexity region
|
1401 |
1412 |
N/A |
INTRINSIC |
|
low complexity region
|
1475 |
1492 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000225591
AA Change: D412G
PolyPhen 2
Score 0.005 (Sensitivity: 0.97; Specificity: 0.74)
|
| Coding Region Coverage |
- 1x: 99.1%
- 3x: 98.5%
- 10x: 97.0%
- 20x: 94.5%
|
| Validation Efficiency |
|
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a member of the kinesin family of microtubule-based motor proteins that function in the positioning of endosomes. This family member can direct mannose-6-phosphate receptor-containing vesicles from the trans-Golgi network to the plasma membrane, and it is necessary for the steady-state distribution of late endosomes/lysosomes. It is also required for the translocation of FYVE-CENT and TTC19 from the centrosome to the midbody during cytokinesis, and it plays a role in melanosome maturation. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Aug 2011]
PHENOTYPE: Mice homozygous for a knock-out allele exhibit increased anxiety. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 82 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 1700025C18Rik |
T |
C |
2: 164,920,946 (GRCm39) |
D29G |
unknown |
Het |
| Abca13 |
A |
T |
11: 9,240,619 (GRCm39) |
L827F |
probably damaging |
Het |
| Abca8a |
A |
G |
11: 109,961,213 (GRCm39) |
F570L |
probably damaging |
Het |
| Adck1 |
T |
A |
12: 88,427,862 (GRCm39) |
I493N |
probably damaging |
Het |
| Adra2c |
T |
C |
5: 35,437,656 (GRCm39) |
C143R |
probably damaging |
Het |
| Afg2a |
T |
C |
3: 37,632,911 (GRCm39) |
V839A |
possibly damaging |
Het |
| Akap13 |
C |
T |
7: 75,354,279 (GRCm39) |
T1800M |
probably damaging |
Het |
| Angpt2 |
T |
C |
8: 18,755,747 (GRCm39) |
N240S |
probably damaging |
Het |
| Apob |
G |
A |
12: 8,057,751 (GRCm39) |
D2078N |
possibly damaging |
Het |
| Atp8b1 |
T |
C |
18: 64,673,405 (GRCm39) |
N989S |
probably damaging |
Het |
| B3gnt2 |
T |
C |
11: 22,786,621 (GRCm39) |
D189G |
probably damaging |
Het |
| Bcam |
G |
A |
7: 19,494,274 (GRCm39) |
T374M |
probably benign |
Het |
| Blm |
T |
C |
7: 80,155,674 (GRCm39) |
D335G |
probably benign |
Het |
| Cbfa2t2 |
T |
C |
2: 154,359,727 (GRCm39) |
L264P |
probably damaging |
Het |
| Col4a2 |
T |
C |
8: 11,495,086 (GRCm39) |
F1515L |
probably benign |
Het |
| Csf2ra |
T |
G |
19: 61,215,331 (GRCm39) |
M95L |
probably benign |
Het |
| Cyp2c70 |
T |
A |
19: 40,152,856 (GRCm39) |
T300S |
possibly damaging |
Het |
| Cyp4f15 |
A |
T |
17: 32,921,133 (GRCm39) |
H440L |
probably damaging |
Het |
| Dcaf1 |
T |
A |
9: 106,716,287 (GRCm39) |
D360E |
probably benign |
Het |
| Ddr2 |
T |
C |
1: 169,812,537 (GRCm39) |
M652V |
probably damaging |
Het |
| Dnah2 |
T |
A |
11: 69,327,896 (GRCm39) |
I3370F |
probably damaging |
Het |
| Dpysl5 |
G |
A |
5: 30,948,941 (GRCm39) |
D399N |
probably damaging |
Het |
| Efemp1 |
G |
T |
11: 28,871,613 (GRCm39) |
R376L |
probably damaging |
Het |
| Efl1 |
A |
C |
7: 82,402,917 (GRCm39) |
D673A |
probably damaging |
Het |
| Eid1 |
A |
G |
2: 125,515,121 (GRCm39) |
M4V |
probably benign |
Het |
| Emc10 |
G |
A |
7: 44,142,616 (GRCm39) |
R109W |
probably damaging |
Het |
| Emilin3 |
G |
A |
2: 160,751,530 (GRCm39) |
R170C |
possibly damaging |
Het |
| Erap1 |
T |
C |
13: 74,812,270 (GRCm39) |
W362R |
probably damaging |
Het |
| Fam234a |
A |
G |
17: 26,437,290 (GRCm39) |
F91L |
probably benign |
Het |
| Flnc |
G |
A |
6: 29,443,796 (GRCm39) |
|
probably null |
Het |
| Fsip2 |
A |
G |
2: 82,813,076 (GRCm39) |
K3132E |
possibly damaging |
Het |
| Garin5b |
A |
T |
7: 4,762,397 (GRCm39) |
I244N |
probably damaging |
Het |
| Gm10608 |
CAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGA |
CAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGA |
9: 118,989,784 (GRCm39) |
|
probably benign |
Het |
| Gnl3 |
A |
G |
14: 30,738,326 (GRCm39) |
|
probably null |
Het |
| Has1 |
A |
T |
17: 18,068,532 (GRCm39) |
I274N |
probably damaging |
Het |
| Ift70a1 |
A |
G |
2: 75,811,801 (GRCm39) |
L94P |
probably benign |
Het |
| Itsn1 |
T |
C |
16: 91,702,389 (GRCm39) |
|
probably null |
Het |
| Kcnh8 |
GAGACCAACGAGCAGCTGATGCTTCAGA |
GAGA |
17: 53,032,934 (GRCm39) |
74 |
probably benign |
Het |
| Klhl20 |
A |
T |
1: 160,930,608 (GRCm39) |
M298K |
probably damaging |
Het |
| Kynu |
G |
T |
2: 43,494,289 (GRCm39) |
G241* |
probably null |
Het |
| Lrif1 |
G |
T |
3: 106,639,522 (GRCm39) |
L202F |
possibly damaging |
Het |
| Lrp5 |
T |
C |
19: 3,660,056 (GRCm39) |
K1003E |
probably benign |
Het |
| Mamdc2 |
T |
C |
19: 23,311,393 (GRCm39) |
D487G |
probably damaging |
Het |
| Mapk8ip1 |
A |
G |
2: 92,221,379 (GRCm39) |
|
probably null |
Het |
| Mettl25 |
T |
A |
10: 105,633,167 (GRCm39) |
E425D |
probably benign |
Het |
| Midn |
G |
T |
10: 79,985,949 (GRCm39) |
R13L |
possibly damaging |
Het |
| Mtmr9 |
T |
C |
14: 63,777,713 (GRCm39) |
Y136C |
possibly damaging |
Het |
| Mylk |
G |
A |
16: 34,817,187 (GRCm39) |
V61M |
probably damaging |
Het |
| Nalcn |
T |
C |
14: 123,831,993 (GRCm39) |
|
probably null |
Het |
| Nle1 |
G |
T |
11: 82,796,373 (GRCm39) |
P166Q |
probably damaging |
Het |
| Nr4a3 |
G |
A |
4: 48,083,252 (GRCm39) |
C595Y |
probably damaging |
Het |
| Or10d4 |
A |
G |
9: 39,580,851 (GRCm39) |
Y166C |
probably damaging |
Het |
| Or4g7 |
G |
T |
2: 111,309,532 (GRCm39) |
M134I |
probably benign |
Het |
| Or4l15 |
A |
G |
14: 50,197,959 (GRCm39) |
I190T |
probably benign |
Het |
| Or5w1b |
C |
T |
2: 87,476,396 (GRCm39) |
V24M |
probably benign |
Het |
| Or8b1 |
A |
T |
9: 38,399,309 (GRCm39) |
|
probably null |
Het |
| Pds5a |
T |
A |
5: 65,805,350 (GRCm39) |
|
probably null |
Het |
| Pitpnm1 |
T |
C |
19: 4,161,873 (GRCm39) |
V955A |
probably benign |
Het |
| Plcb1 |
T |
A |
2: 135,204,340 (GRCm39) |
I898N |
possibly damaging |
Het |
| Plcl2 |
G |
A |
17: 50,913,722 (GRCm39) |
V244M |
probably damaging |
Het |
| Plk1 |
A |
G |
7: 121,761,663 (GRCm39) |
K257R |
probably damaging |
Het |
| Prkcg |
A |
T |
7: 3,372,066 (GRCm39) |
T460S |
probably damaging |
Het |
| Prl7d1 |
G |
A |
13: 27,894,156 (GRCm39) |
H138Y |
probably damaging |
Het |
| Prss35 |
A |
G |
9: 86,637,565 (GRCm39) |
S112G |
probably benign |
Het |
| Ptprj |
C |
T |
2: 90,294,958 (GRCm39) |
V417M |
probably damaging |
Het |
| Pwwp2b |
A |
T |
7: 138,836,067 (GRCm39) |
I503F |
possibly damaging |
Het |
| Rasgrp2 |
T |
C |
19: 6,463,195 (GRCm39) |
V498A |
probably benign |
Het |
| Sall1 |
A |
G |
8: 89,755,037 (GRCm39) |
V1314A |
probably benign |
Het |
| Sema6c |
A |
G |
3: 95,078,545 (GRCm39) |
I549V |
probably benign |
Het |
| Slc17a1 |
A |
G |
13: 24,062,522 (GRCm39) |
S230G |
probably benign |
Het |
| Slc5a4a |
T |
G |
10: 75,989,414 (GRCm39) |
F106V |
probably benign |
Het |
| Stat6 |
T |
C |
10: 127,486,665 (GRCm39) |
L147P |
probably damaging |
Het |
| Taar7d |
T |
A |
10: 23,903,642 (GRCm39) |
S175T |
probably benign |
Het |
| Tasor2 |
A |
T |
13: 3,626,770 (GRCm39) |
I1060K |
probably benign |
Het |
| Tmem132b |
A |
G |
5: 125,700,080 (GRCm39) |
Q206R |
probably benign |
Het |
| Tmem229a |
T |
C |
6: 24,955,061 (GRCm39) |
D231G |
probably benign |
Het |
| Trim66 |
A |
G |
7: 109,071,439 (GRCm39) |
|
probably null |
Het |
| Ttll9 |
A |
T |
2: 152,844,214 (GRCm39) |
E374V |
probably damaging |
Het |
| Vmn2r69 |
A |
T |
7: 85,056,493 (GRCm39) |
D548E |
probably damaging |
Het |
| Zcchc2 |
T |
A |
1: 105,931,851 (GRCm39) |
|
probably null |
Het |
| Zfp282 |
T |
A |
6: 47,874,721 (GRCm39) |
|
probably null |
Het |
| Zfp352 |
A |
G |
4: 90,113,408 (GRCm39) |
E516G |
probably benign |
Het |
|
| Other mutations in Kif13a |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL01084:Kif13a
|
APN |
13 |
46,904,110 (GRCm39) |
splice site |
probably benign |
|
|
IGL01433:Kif13a
|
APN |
13 |
46,926,384 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01528:Kif13a
|
APN |
13 |
47,018,313 (GRCm39) |
splice site |
probably benign |
|
|
IGL01536:Kif13a
|
APN |
13 |
46,905,765 (GRCm39) |
missense |
probably damaging |
0.96 |
|
IGL01620:Kif13a
|
APN |
13 |
47,018,296 (GRCm39) |
missense |
probably benign |
|
|
IGL02020:Kif13a
|
APN |
13 |
46,947,495 (GRCm39) |
missense |
probably benign |
0.05 |
|
IGL02142:Kif13a
|
APN |
13 |
46,925,011 (GRCm39) |
missense |
probably benign |
0.04 |
|
IGL02375:Kif13a
|
APN |
13 |
46,978,698 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02407:Kif13a
|
APN |
13 |
46,938,769 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL02476:Kif13a
|
APN |
13 |
46,938,772 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03038:Kif13a
|
APN |
13 |
46,926,314 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03053:Kif13a
|
APN |
13 |
46,905,564 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL03366:Kif13a
|
APN |
13 |
46,918,099 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0025:Kif13a
|
UTSW |
13 |
46,939,987 (GRCm39) |
critical splice donor site |
probably null |
|
|
R0106:Kif13a
|
UTSW |
13 |
46,978,823 (GRCm39) |
splice site |
probably benign |
|
|
R0106:Kif13a
|
UTSW |
13 |
46,978,823 (GRCm39) |
splice site |
probably benign |
|
|
R0135:Kif13a
|
UTSW |
13 |
46,947,419 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0137:Kif13a
|
UTSW |
13 |
46,918,079 (GRCm39) |
missense |
probably benign |
0.38 |
|
R0243:Kif13a
|
UTSW |
13 |
46,944,827 (GRCm39) |
missense |
probably benign |
0.24 |
|
R0346:Kif13a
|
UTSW |
13 |
46,967,695 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R0403:Kif13a
|
UTSW |
13 |
46,944,877 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0492:Kif13a
|
UTSW |
13 |
46,966,218 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R0607:Kif13a
|
UTSW |
13 |
46,956,187 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R0631:Kif13a
|
UTSW |
13 |
46,932,364 (GRCm39) |
unclassified |
probably benign |
|
|
R0654:Kif13a
|
UTSW |
13 |
46,966,218 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R0697:Kif13a
|
UTSW |
13 |
47,001,813 (GRCm39) |
missense |
probably benign |
0.19 |
|
R0699:Kif13a
|
UTSW |
13 |
46,952,689 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R0715:Kif13a
|
UTSW |
13 |
46,966,299 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R0834:Kif13a
|
UTSW |
13 |
46,967,712 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R0903:Kif13a
|
UTSW |
13 |
47,082,735 (GRCm39) |
missense |
possibly damaging |
0.75 |
|
R1419:Kif13a
|
UTSW |
13 |
46,978,711 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1428:Kif13a
|
UTSW |
13 |
46,944,987 (GRCm39) |
splice site |
probably benign |
|
|
R1449:Kif13a
|
UTSW |
13 |
46,966,212 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1463:Kif13a
|
UTSW |
13 |
47,083,088 (GRCm39) |
missense |
possibly damaging |
0.75 |
|
R1541:Kif13a
|
UTSW |
13 |
46,962,689 (GRCm39) |
missense |
probably benign |
|
|
R1579:Kif13a
|
UTSW |
13 |
46,906,332 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R1582:Kif13a
|
UTSW |
13 |
46,947,398 (GRCm39) |
missense |
probably benign |
0.03 |
|
R1644:Kif13a
|
UTSW |
13 |
46,947,398 (GRCm39) |
missense |
probably benign |
0.31 |
|
R1752:Kif13a
|
UTSW |
13 |
46,951,885 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1755:Kif13a
|
UTSW |
13 |
46,927,154 (GRCm39) |
missense |
possibly damaging |
0.50 |
|
R1755:Kif13a
|
UTSW |
13 |
46,906,089 (GRCm39) |
missense |
possibly damaging |
0.73 |
|
R1858:Kif13a
|
UTSW |
13 |
47,018,314 (GRCm39) |
splice site |
probably benign |
|
|
R1891:Kif13a
|
UTSW |
13 |
47,082,695 (GRCm39) |
missense |
possibly damaging |
0.63 |
|
R1902:Kif13a
|
UTSW |
13 |
46,941,638 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1928:Kif13a
|
UTSW |
13 |
46,966,221 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1960:Kif13a
|
UTSW |
13 |
47,018,314 (GRCm39) |
splice site |
probably benign |
|
|
R1961:Kif13a
|
UTSW |
13 |
47,018,314 (GRCm39) |
splice site |
probably benign |
|
|
R2139:Kif13a
|
UTSW |
13 |
46,905,945 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R2174:Kif13a
|
UTSW |
13 |
46,922,652 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R2407:Kif13a
|
UTSW |
13 |
46,930,573 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2504:Kif13a
|
UTSW |
13 |
46,967,676 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3122:Kif13a
|
UTSW |
13 |
46,918,072 (GRCm39) |
splice site |
probably benign |
|
|
R3499:Kif13a
|
UTSW |
13 |
46,978,815 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3905:Kif13a
|
UTSW |
13 |
46,956,166 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4474:Kif13a
|
UTSW |
13 |
46,967,631 (GRCm39) |
splice site |
probably null |
|
|
R4771:Kif13a
|
UTSW |
13 |
46,978,687 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4838:Kif13a
|
UTSW |
13 |
46,980,224 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4924:Kif13a
|
UTSW |
13 |
47,083,075 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4931:Kif13a
|
UTSW |
13 |
46,962,531 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R4980:Kif13a
|
UTSW |
13 |
46,906,222 (GRCm39) |
missense |
possibly damaging |
0.76 |
|
R4992:Kif13a
|
UTSW |
13 |
46,930,639 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R5047:Kif13a
|
UTSW |
13 |
46,941,561 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5054:Kif13a
|
UTSW |
13 |
46,956,122 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5141:Kif13a
|
UTSW |
13 |
46,906,197 (GRCm39) |
missense |
probably benign |
|
|
R5329:Kif13a
|
UTSW |
13 |
46,928,877 (GRCm39) |
critical splice donor site |
probably null |
|
|
R5429:Kif13a
|
UTSW |
13 |
46,926,245 (GRCm39) |
critical splice donor site |
probably null |
|
|
R5499:Kif13a
|
UTSW |
13 |
46,986,212 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5509:Kif13a
|
UTSW |
13 |
46,905,591 (GRCm39) |
missense |
probably benign |
0.13 |
|
R5594:Kif13a
|
UTSW |
13 |
46,906,338 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5921:Kif13a
|
UTSW |
13 |
46,978,776 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5964:Kif13a
|
UTSW |
13 |
46,925,000 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6115:Kif13a
|
UTSW |
13 |
46,954,789 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6317:Kif13a
|
UTSW |
13 |
46,980,233 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6318:Kif13a
|
UTSW |
13 |
46,968,683 (GRCm39) |
splice site |
probably null |
|
|
R6393:Kif13a
|
UTSW |
13 |
46,905,931 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R6394:Kif13a
|
UTSW |
13 |
46,905,931 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R6395:Kif13a
|
UTSW |
13 |
46,905,931 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R6735:Kif13a
|
UTSW |
13 |
46,906,222 (GRCm39) |
missense |
possibly damaging |
0.76 |
|
R7037:Kif13a
|
UTSW |
13 |
46,905,931 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R7038:Kif13a
|
UTSW |
13 |
46,905,931 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R7039:Kif13a
|
UTSW |
13 |
46,905,931 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R7237:Kif13a
|
UTSW |
13 |
46,962,632 (GRCm39) |
critical splice donor site |
probably null |
|
|
R7285:Kif13a
|
UTSW |
13 |
46,905,931 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R7286:Kif13a
|
UTSW |
13 |
46,905,931 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R7287:Kif13a
|
UTSW |
13 |
46,905,931 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R7341:Kif13a
|
UTSW |
13 |
46,980,221 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7693:Kif13a
|
UTSW |
13 |
46,904,089 (GRCm39) |
missense |
probably benign |
0.01 |
|
R7761:Kif13a
|
UTSW |
13 |
46,951,955 (GRCm39) |
missense |
probably benign |
|
|
R8098:Kif13a
|
UTSW |
13 |
46,968,780 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8171:Kif13a
|
UTSW |
13 |
46,932,444 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8271:Kif13a
|
UTSW |
13 |
46,906,057 (GRCm39) |
missense |
probably benign |
0.01 |
|
R8806:Kif13a
|
UTSW |
13 |
46,914,813 (GRCm39) |
missense |
possibly damaging |
0.49 |
|
R8871:Kif13a
|
UTSW |
13 |
46,984,279 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8877:Kif13a
|
UTSW |
13 |
46,954,921 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R8906:Kif13a
|
UTSW |
13 |
46,927,154 (GRCm39) |
missense |
probably benign |
0.17 |
|
R9028:Kif13a
|
UTSW |
13 |
46,951,841 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9058:Kif13a
|
UTSW |
13 |
46,944,941 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9062:Kif13a
|
UTSW |
13 |
46,941,536 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R9070:Kif13a
|
UTSW |
13 |
46,905,934 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9083:Kif13a
|
UTSW |
13 |
46,966,263 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9250:Kif13a
|
UTSW |
13 |
46,928,909 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9328:Kif13a
|
UTSW |
13 |
46,951,838 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9360:Kif13a
|
UTSW |
13 |
46,962,472 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9369:Kif13a
|
UTSW |
13 |
46,940,099 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9589:Kif13a
|
UTSW |
13 |
46,956,020 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9749:Kif13a
|
UTSW |
13 |
46,914,227 (GRCm39) |
missense |
probably damaging |
0.96 |
|
X0013:Kif13a
|
UTSW |
13 |
47,082,746 (GRCm39) |
missense |
possibly damaging |
0.49 |
|
| Predicted Primers |
PCR Primer
(F):5'- TCTTACTTTGACATAACTGCAATAAGC -3'
(R):5'- AATGTTTGAAGGTAAGCTTTTGGC -3'
Sequencing Primer
(F):5'- CAATAAGCAAGGGGAAAGGGCC -3'
(R):5'- ATGCCGTTATCCGATGAGAC -3'
|
| Posted On |
2014-08-25 |
Incidental Mutation