Mutagenetix > Incidental Mutation

Incidental Mutation 'R2037:Fsip2'

224727

Institutional Source

Beutler Lab

Gene Symbol

Fsip2

Ensembl Gene

ENSMUSG00000075249

Gene Name

fibrous sheath-interacting protein 2

Synonyms

OTTMUSG00000013335

MMRRC Submission

040044-MU

Accession Numbers

Essential gene?

Probably non essential (E-score: 0.123) question?

Stock #

R2037 (G1)

Quality Score

225

Status

Not validated

Chromosome

Chromosomal Location

82773978-82839281 bp(+) (GRCm39)

Type of Mutation

missense

DNA Base Change (assembly)

A to G at 82808856 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Aspartic acid to Glycine at position 1725 (D1725G)

Ref Sequence

ENSEMBL: ENSMUSP00000120314 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000143764]

AlphaFold

no structure available at present

Predicted Effect

probably benign
Transcript: ENSMUST00000132967

SMART Domains

Protein: ENSMUSP00000122350
Gene: ENSMUSG00000075249

Domain	Start	End	E-Value	Type
low complexity region	22	38	N/A	INTRINSIC
low complexity region	79	90	N/A	INTRINSIC
low complexity region	381	392	N/A	INTRINSIC
low complexity region	411	430	N/A	INTRINSIC
low complexity region	735	746	N/A	INTRINSIC
low complexity region	953	962	N/A	INTRINSIC

Predicted Effect

probably damaging
Transcript: ENSMUST00000143764
AA Change: D1725G

PolyPhen 2 Score 0.985 (Sensitivity: 0.74; Specificity: 0.96)

SMART Domains

Protein: ENSMUSP00000120314
Gene: ENSMUSG00000075249
AA Change: D1725G

Domain	Start	End	E-Value	Type
coiled coil region	271	297	N/A	INTRINSIC
low complexity region	544	561	N/A	INTRINSIC
low complexity region	586	597	N/A	INTRINSIC
low complexity region	882	895	N/A	INTRINSIC
low complexity region	925	939	N/A	INTRINSIC
low complexity region	1115	1120	N/A	INTRINSIC
low complexity region	1531	1545	N/A	INTRINSIC
low complexity region	2044	2057	N/A	INTRINSIC
low complexity region	2507	2523	N/A	INTRINSIC
low complexity region	2564	2575	N/A	INTRINSIC
low complexity region	2866	2877	N/A	INTRINSIC
low complexity region	2896	2915	N/A	INTRINSIC
low complexity region	3220	3231	N/A	INTRINSIC
low complexity region	3438	3447	N/A	INTRINSIC
Pfam:FSIP2	4045	4408	3.5e-42	PFAM
Pfam:FSIP2	4375	4613	7.7e-26	PFAM
Pfam:FSIP2	4622	4932	4.3e-17	PFAM
Pfam:FSIP2	4903	5454	7e-27	PFAM
low complexity region	5507	5522	N/A	INTRINSIC
low complexity region	5769	5780	N/A	INTRINSIC
low complexity region	5834	5846	N/A	INTRINSIC
low complexity region	5851	5867	N/A	INTRINSIC
Pfam:FSIP2	5998	6867	N/A	PFAM
low complexity region	6977	6990	N/A	INTRINSIC

Coding Region Coverage

1x: 99.2%
3x: 98.5%
10x: 96.9%
20x: 94.0%

Validation Efficiency

MGI Phenotype

FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a protein associated with the sperm fibrous sheath. Genes encoding most of the fibrous-sheath associated proteins genes are transcribed only during the postmeiotic period of spermatogenesis. The protein encoded by this gene is specific to spermatogenic cells. Copy number variation in this gene may be associated with testicular germ cell tumors. Pseudogenes associated with this gene are reported on chromosomes 2 and X. [provided by RefSeq, Aug 2016]

Allele List at MGI

Other mutations in this stock

Total: 70 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Abca8a	A	T	11: 109,980,810 (GRCm39)		probably null	Het
AI987944	T	C	7: 41,023,815 (GRCm39)	Y391C	probably benign	Het
Ankfn1	A	T	11: 89,346,946 (GRCm39)	S296T	probably benign	Het
Apob	A	G	12: 8,057,488 (GRCm39)	D1957G	probably benign	Het
Baz1a	G	T	12: 54,976,431 (GRCm39)	P415Q	probably damaging	Het
Brca2	T	A	5: 150,464,134 (GRCm39)	H1299Q	probably benign	Het
C7	G	T	15: 5,063,720 (GRCm39)	S227*	probably null	Het
Catsperb	A	T	12: 101,474,221 (GRCm39)	R306S	probably damaging	Het
Cbx3	T	A	6: 51,448,793 (GRCm39)		probably null	Het
Ccnt2	A	G	1: 127,731,136 (GRCm39)	Y671C	probably damaging	Het
Crocc	A	G	4: 140,774,253 (GRCm39)		probably null	Het
Ctr9	G	A	7: 110,646,014 (GRCm39)	V669I	probably benign	Het
Dck	T	G	5: 88,920,576 (GRCm39)	Y99D	probably damaging	Het
Ddx52	T	A	11: 83,835,432 (GRCm39)	D119E	probably benign	Het
Dnah10	A	T	5: 124,823,768 (GRCm39)	K596N	probably benign	Het
Dnah7a	A	T	1: 53,621,741 (GRCm39)	V1128E	probably benign	Het
Dph1	A	T	11: 75,076,679 (GRCm39)		probably null	Het
Enah	G	A	1: 181,749,537 (GRCm39)	P415L	probably damaging	Het
Enthd1	A	G	15: 80,444,550 (GRCm39)	S2P	possibly damaging	Het
Erc1	A	C	6: 119,699,216 (GRCm39)	V802G	possibly damaging	Het
F8	ATCTCTCTC	ATCTCTC	X: 74,366,604 (GRCm39)		probably null	Het
Fam169a	C	A	13: 97,243,600 (GRCm39)	A210E	probably benign	Het
Fcmr	A	G	1: 130,806,070 (GRCm39)	D342G	possibly damaging	Het
Fgfr4	T	G	13: 55,315,702 (GRCm39)	V743G	possibly damaging	Het
Heatr5b	A	T	17: 79,136,934 (GRCm39)	C195*	probably null	Het
Herc2	G	A	7: 55,855,709 (GRCm39)	A3882T	probably damaging	Het
Il20	T	A	1: 130,836,115 (GRCm39)	N143Y	probably damaging	Het
Inpp5b	A	G	4: 124,692,092 (GRCm39)	S892G	probably damaging	Het
Ipo13	A	T	4: 117,761,858 (GRCm39)	Y447*	probably null	Het
Itprid1	A	G	6: 55,874,860 (GRCm39)	N270S	probably benign	Het
Kbtbd12	A	T	6: 88,594,779 (GRCm39)	N350K	probably benign	Het
Kiz	T	C	2: 146,811,880 (GRCm39)	F663S	probably damaging	Het
Matn2	A	G	15: 34,433,263 (GRCm39)	D870G	probably benign	Het
Methig1	C	T	15: 100,251,467 (GRCm39)	A126V	probably benign	Het
Mme	A	G	3: 63,235,681 (GRCm39)	D209G	probably null	Het
Mroh4	A	G	15: 74,481,610 (GRCm39)	F811L	possibly damaging	Het
Myo9b	G	T	8: 71,743,510 (GRCm39)	K190N	probably damaging	Het
Ncf1	T	C	5: 134,258,406 (GRCm39)	I6V	probably damaging	Het
Nmt2	T	C	2: 3,310,618 (GRCm39)	F121L	probably damaging	Het
Nol10	A	G	12: 17,411,152 (GRCm39)	D183G	probably benign	Het
Nsun7	T	C	5: 66,418,429 (GRCm39)	V53A	probably benign	Het
Or10u4	T	C	10: 129,802,009 (GRCm39)	I187V	probably benign	Het
Or8j3	T	C	2: 86,028,176 (GRCm39)	S307G	probably benign	Het
Or8k22	T	C	2: 86,162,774 (GRCm39)	N309D	probably benign	Het
Pappa2	A	T	1: 158,784,214 (GRCm39)	Y265*	probably null	Het
Pigg	G	A	5: 108,486,518 (GRCm39)	A724T	probably damaging	Het
Pik3r4	C	T	9: 105,527,534 (GRCm39)	R296C	probably benign	Het
Pkhd1l1	A	G	15: 44,431,617 (GRCm39)		probably null	Het
Pld4	A	G	12: 112,734,992 (GRCm39)	D483G	probably damaging	Het
Ppip5k1	C	T	2: 121,173,674 (GRCm39)	R399H	probably damaging	Het
Qrfpr	A	T	3: 36,236,806 (GRCm39)	H198Q	probably damaging	Het
Rasgrf2	A	T	13: 92,050,748 (GRCm39)	D883E	probably damaging	Het
Retnlg	T	C	16: 48,694,615 (GRCm39)	C88R	probably damaging	Het
Sin3a	C	T	9: 57,004,109 (GRCm39)	T287I	probably benign	Het
Slc44a1	GCC	GCCCCC	4: 53,563,243 (GRCm39)		probably benign	Het
Sppl2c	G	C	11: 104,077,307 (GRCm39)	V36L	probably benign	Het
Srp72	T	A	5: 77,124,338 (GRCm39)	I68N	probably damaging	Het
Srrm3	T	A	5: 135,883,231 (GRCm39)	S195R	probably damaging	Het
Srrm4	T	A	5: 116,605,887 (GRCm39)		probably benign	Het
Ssb	A	G	2: 69,699,163 (GRCm39)	S199G	probably benign	Het
Sult2a6	T	A	7: 13,988,634 (GRCm39)	Y42F	probably damaging	Het
Syne2	A	G	12: 76,072,343 (GRCm39)	T120A	probably benign	Het
Tas1r1	A	G	4: 152,112,627 (GRCm39)	F809L	probably damaging	Het
Tead3	A	G	17: 28,555,544 (GRCm39)	S117P	probably damaging	Het
Tefm	C	T	11: 80,031,056 (GRCm39)	R60H	probably damaging	Het
Tmem104	G	A	11: 115,092,221 (GRCm39)	R110H	possibly damaging	Het
Tnxb	G	A	17: 34,918,179 (GRCm39)	G2364D	probably damaging	Het
Vmn1r211	T	A	13: 23,036,134 (GRCm39)	I178F	probably damaging	Het
Vmn1r6	A	T	6: 56,980,109 (GRCm39)	Y235F	probably damaging	Het
Xrcc5	C	A	1: 72,385,529 (GRCm39)	T540K	probably benign	Het

Other mutations in Fsip2

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00094:Fsip2	APN	2	82,820,730 (GRCm39)	missense	probably benign	0.18
IGL00557:Fsip2	APN	2	82,821,657 (GRCm39)	missense	possibly damaging	0.53
IGL01343:Fsip2	APN	2	82,830,163 (GRCm39)	missense	possibly damaging	0.53
IGL01387:Fsip2	APN	2	82,823,326 (GRCm39)	missense	possibly damaging	0.71
IGL01523:Fsip2	APN	2	82,807,863 (GRCm39)	missense	probably benign
IGL01554:Fsip2	APN	2	82,807,622 (GRCm39)	missense	possibly damaging	0.68
IGL01650:Fsip2	APN	2	82,821,430 (GRCm39)	missense	probably benign	0.33
IGL01809:Fsip2	APN	2	82,808,691 (GRCm39)	missense	possibly damaging	0.80
IGL01826:Fsip2	APN	2	82,812,983 (GRCm39)	missense	probably benign	0.18
IGL01830:Fsip2	APN	2	82,815,273 (GRCm39)	missense	probably benign
IGL01918:Fsip2	APN	2	82,822,482 (GRCm39)	missense	possibly damaging	0.71
IGL01932:Fsip2	APN	2	82,824,349 (GRCm39)	missense	possibly damaging	0.71
IGL01989:Fsip2	APN	2	82,824,211 (GRCm39)	missense	probably damaging	0.99
IGL02096:Fsip2	APN	2	82,822,204 (GRCm39)	missense	possibly damaging	0.85
IGL02153:Fsip2	APN	2	82,809,065 (GRCm39)	missense	probably benign
IGL02155:Fsip2	APN	2	82,828,696 (GRCm39)	missense	probably benign
IGL02219:Fsip2	APN	2	82,808,174 (GRCm39)	missense	probably benign	0.07
IGL02248:Fsip2	APN	2	82,813,116 (GRCm39)	missense	possibly damaging	0.73
IGL02316:Fsip2	APN	2	82,809,137 (GRCm39)	missense	probably benign
IGL02478:Fsip2	APN	2	82,814,736 (GRCm39)	missense	probably benign	0.00
IGL02504:Fsip2	APN	2	82,809,199 (GRCm39)	missense	possibly damaging	0.83
IGL02572:Fsip2	APN	2	82,822,347 (GRCm39)	missense	probably benign	0.32
IGL02625:Fsip2	APN	2	82,779,836 (GRCm39)	missense	probably benign	0.00
IGL02665:Fsip2	APN	2	82,823,407 (GRCm39)	missense	probably damaging	1.00
IGL02668:Fsip2	APN	2	82,828,662 (GRCm39)	missense	probably benign	0.06
IGL02676:Fsip2	APN	2	82,812,501 (GRCm39)	missense	possibly damaging	0.53
IGL02717:Fsip2	APN	2	82,781,370 (GRCm39)	splice site	probably benign
IGL02805:Fsip2	APN	2	82,823,839 (GRCm39)	missense	probably benign	0.01
IGL02943:Fsip2	APN	2	82,822,701 (GRCm39)	missense	probably benign	0.32
IGL02965:Fsip2	APN	2	82,813,398 (GRCm39)	missense	probably benign	0.33
IGL03001:Fsip2	APN	2	82,820,968 (GRCm39)	intron	probably benign
IGL03076:Fsip2	APN	2	82,812,482 (GRCm39)	missense	possibly damaging	0.96
IGL03229:Fsip2	APN	2	82,808,420 (GRCm39)	missense	possibly damaging	0.86
IGL03353:Fsip2	APN	2	82,807,737 (GRCm39)	missense	possibly damaging	0.85
IGL03401:Fsip2	APN	2	82,820,814 (GRCm39)	missense	probably benign
bubblegum	UTSW	2	82,823,184 (GRCm39)	missense	probably benign	0.16
Dao	UTSW	2	82,823,494 (GRCm39)	missense	probably damaging	0.97
engulf	UTSW	2	82,815,120 (GRCm39)	missense	probably damaging	0.98
envelope	UTSW	2	82,811,085 (GRCm39)	missense	probably benign	0.07
gladius	UTSW	2	82,812,293 (GRCm39)	missense	possibly damaging	0.68
glove	UTSW	2	82,808,738 (GRCm39)	missense	possibly damaging	0.85
Katana	UTSW	2	82,819,860 (GRCm39)	missense	probably benign	0.07
scarf	UTSW	2	82,817,235 (GRCm39)	missense	probably benign
Sock	UTSW	2	82,828,524 (GRCm39)	missense	probably benign	0.00
swaddle	UTSW	2	82,813,772 (GRCm39)	missense	possibly damaging	0.93
wrap	UTSW	2	82,817,164 (GRCm39)	missense	probably benign	0.04
Wrapper	UTSW	2	82,820,430 (GRCm39)	missense	possibly damaging	0.71
D4186:Fsip2	UTSW	2	82,818,756 (GRCm39)	missense	probably benign	0.32
FR4976:Fsip2	UTSW	2	82,814,709 (GRCm39)	critical splice acceptor site	probably benign
FR4976:Fsip2	UTSW	2	82,814,706 (GRCm39)	critical splice acceptor site	probably benign
PIT4382001:Fsip2	UTSW	2	82,821,196 (GRCm39)	missense	possibly damaging	0.86
R0017:Fsip2	UTSW	2	82,822,416 (GRCm39)	missense	probably damaging	0.98
R0017:Fsip2	UTSW	2	82,822,416 (GRCm39)	missense	probably damaging	0.98
R0021:Fsip2	UTSW	2	82,830,201 (GRCm39)	splice site	probably benign
R0054:Fsip2	UTSW	2	82,817,299 (GRCm39)	missense	possibly damaging	0.85
R0054:Fsip2	UTSW	2	82,817,299 (GRCm39)	missense	possibly damaging	0.85
R0054:Fsip2	UTSW	2	82,806,952 (GRCm39)	missense	probably damaging	0.96
R0104:Fsip2	UTSW	2	82,809,317 (GRCm39)	missense	possibly damaging	0.91
R0104:Fsip2	UTSW	2	82,809,317 (GRCm39)	missense	possibly damaging	0.91
R0127:Fsip2	UTSW	2	82,815,269 (GRCm39)	missense	probably benign	0.28
R0131:Fsip2	UTSW	2	82,821,465 (GRCm39)	missense	probably benign
R0149:Fsip2	UTSW	2	82,805,849 (GRCm39)	missense	possibly damaging	0.93
R0167:Fsip2	UTSW	2	82,811,151 (GRCm39)	missense	possibly damaging	0.53
R0190:Fsip2	UTSW	2	82,815,521 (GRCm39)	missense	possibly damaging	0.73
R0323:Fsip2	UTSW	2	82,816,240 (GRCm39)	missense	probably benign	0.33
R0358:Fsip2	UTSW	2	82,813,677 (GRCm39)	missense	possibly damaging	0.56
R0361:Fsip2	UTSW	2	82,805,849 (GRCm39)	missense	possibly damaging	0.93
R0369:Fsip2	UTSW	2	82,814,908 (GRCm39)	missense	probably benign	0.33
R0394:Fsip2	UTSW	2	82,821,419 (GRCm39)	missense	possibly damaging	0.70
R0532:Fsip2	UTSW	2	82,808,129 (GRCm39)	missense	probably benign	0.33
R0595:Fsip2	UTSW	2	82,777,296 (GRCm39)	missense	probably damaging	0.99
R0613:Fsip2	UTSW	2	82,824,139 (GRCm39)	missense	probably damaging	0.99
R0614:Fsip2	UTSW	2	82,807,877 (GRCm39)	missense	probably benign	0.15
R0619:Fsip2	UTSW	2	82,774,484 (GRCm39)	missense	probably damaging	1.00
R0626:Fsip2	UTSW	2	82,819,302 (GRCm39)	missense	probably benign	0.06
R0644:Fsip2	UTSW	2	82,807,241 (GRCm39)	missense	probably benign	0.02
R0661:Fsip2	UTSW	2	82,816,513 (GRCm39)	missense	possibly damaging	0.92
R0680:Fsip2	UTSW	2	82,821,703 (GRCm39)	missense	possibly damaging	0.73
R0688:Fsip2	UTSW	2	82,812,683 (GRCm39)	missense	probably benign	0.18
R0881:Fsip2	UTSW	2	82,816,617 (GRCm39)	missense	possibly damaging	0.52
R0919:Fsip2	UTSW	2	82,815,828 (GRCm39)	missense	possibly damaging	0.53
R0973:Fsip2	UTSW	2	82,807,436 (GRCm39)	missense	probably benign	0.05
R0973:Fsip2	UTSW	2	82,807,436 (GRCm39)	missense	probably benign	0.05
R0974:Fsip2	UTSW	2	82,807,436 (GRCm39)	missense	probably benign	0.05
R0976:Fsip2	UTSW	2	82,828,375 (GRCm39)	missense	possibly damaging	0.92
R1025:Fsip2	UTSW	2	82,819,780 (GRCm39)	nonsense	probably null
R1026:Fsip2	UTSW	2	82,818,805 (GRCm39)	missense	possibly damaging	0.52
R1140:Fsip2	UTSW	2	82,805,378 (GRCm39)	missense	probably damaging	0.99
R1170:Fsip2	UTSW	2	82,821,844 (GRCm39)	missense	possibly damaging	0.72
R1180:Fsip2	UTSW	2	82,805,570 (GRCm39)	missense	probably damaging	0.99
R1188:Fsip2	UTSW	2	82,805,361 (GRCm39)	missense	possibly damaging	0.96
R1226:Fsip2	UTSW	2	82,811,355 (GRCm39)	missense	probably damaging	0.96
R1248:Fsip2	UTSW	2	82,820,107 (GRCm39)	missense	possibly damaging	0.93
R1273:Fsip2	UTSW	2	82,819,752 (GRCm39)	missense	possibly damaging	0.92
R1323:Fsip2	UTSW	2	82,816,096 (GRCm39)	missense	probably damaging	1.00
R1323:Fsip2	UTSW	2	82,816,096 (GRCm39)	missense	probably damaging	1.00
R1356:Fsip2	UTSW	2	82,820,089 (GRCm39)	missense	probably benign	0.38
R1413:Fsip2	UTSW	2	82,818,762 (GRCm39)	missense	possibly damaging	0.93
R1430:Fsip2	UTSW	2	82,828,407 (GRCm39)	missense	possibly damaging	0.71
R1475:Fsip2	UTSW	2	82,817,539 (GRCm39)	missense	probably damaging	0.99
R1489:Fsip2	UTSW	2	82,810,155 (GRCm39)	missense	probably benign
R1520:Fsip2	UTSW	2	82,811,058 (GRCm39)	missense	possibly damaging	0.96
R1543:Fsip2	UTSW	2	82,811,931 (GRCm39)	missense	possibly damaging	0.91
R1581:Fsip2	UTSW	2	82,816,626 (GRCm39)	missense	probably damaging	0.98
R1590:Fsip2	UTSW	2	82,813,131 (GRCm39)	missense	probably benign	0.26
R1646:Fsip2	UTSW	2	82,808,861 (GRCm39)	missense	probably benign	0.07
R1678:Fsip2	UTSW	2	82,816,689 (GRCm39)	missense	probably benign
R1700:Fsip2	UTSW	2	82,822,081 (GRCm39)	missense	probably benign	0.33
R1717:Fsip2	UTSW	2	82,805,289 (GRCm39)	missense	possibly damaging	0.68
R1741:Fsip2	UTSW	2	82,820,256 (GRCm39)	missense	probably benign	0.32
R1760:Fsip2	UTSW	2	82,818,055 (GRCm39)	missense	possibly damaging	0.71
R1760:Fsip2	UTSW	2	82,815,240 (GRCm39)	missense	probably benign	0.07
R1760:Fsip2	UTSW	2	82,830,185 (GRCm39)	missense	possibly damaging	0.85
R1789:Fsip2	UTSW	2	82,807,906 (GRCm39)	missense	probably benign	0.00
R1850:Fsip2	UTSW	2	82,814,933 (GRCm39)	missense	possibly damaging	0.72
R1854:Fsip2	UTSW	2	82,823,601 (GRCm39)	missense	possibly damaging	0.84
R1888:Fsip2	UTSW	2	82,774,504 (GRCm39)	missense	probably benign	0.04
R1888:Fsip2	UTSW	2	82,774,504 (GRCm39)	missense	probably benign	0.04
R1905:Fsip2	UTSW	2	82,813,772 (GRCm39)	missense	possibly damaging	0.93
R1907:Fsip2	UTSW	2	82,813,772 (GRCm39)	missense	possibly damaging	0.93
R1920:Fsip2	UTSW	2	82,817,164 (GRCm39)	missense	probably benign	0.04
R1921:Fsip2	UTSW	2	82,817,164 (GRCm39)	missense	probably benign	0.04
R1921:Fsip2	UTSW	2	82,811,127 (GRCm39)	nonsense	probably null
R1931:Fsip2	UTSW	2	82,817,077 (GRCm39)	missense	probably damaging	0.99
R1934:Fsip2	UTSW	2	82,810,902 (GRCm39)	missense	possibly damaging	0.91
R1959:Fsip2	UTSW	2	82,821,894 (GRCm39)	missense	probably benign
R1965:Fsip2	UTSW	2	82,823,124 (GRCm39)	missense	possibly damaging	0.86
R1966:Fsip2	UTSW	2	82,823,124 (GRCm39)	missense	possibly damaging	0.86
R1983:Fsip2	UTSW	2	82,810,175 (GRCm39)	missense	probably benign
R1988:Fsip2	UTSW	2	82,806,861 (GRCm39)	missense	possibly damaging	0.56
R2016:Fsip2	UTSW	2	82,813,076 (GRCm39)	missense	possibly damaging	0.53
R2017:Fsip2	UTSW	2	82,813,076 (GRCm39)	missense	possibly damaging	0.53
R2026:Fsip2	UTSW	2	82,819,788 (GRCm39)	missense	possibly damaging	0.71
R2034:Fsip2	UTSW	2	82,819,838 (GRCm39)	missense	probably benign	0.43
R2070:Fsip2	UTSW	2	82,806,699 (GRCm39)	missense	probably damaging	0.98
R2072:Fsip2	UTSW	2	82,839,159 (GRCm39)	missense	possibly damaging	0.53
R2075:Fsip2	UTSW	2	82,818,923 (GRCm39)	missense	possibly damaging	0.85
R2143:Fsip2	UTSW	2	82,820,615 (GRCm39)	missense	possibly damaging	0.93
R2207:Fsip2	UTSW	2	82,807,823 (GRCm39)	missense	probably benign	0.02
R2256:Fsip2	UTSW	2	82,793,095 (GRCm39)	missense	probably benign	0.07
R2315:Fsip2	UTSW	2	82,805,437 (GRCm39)	missense	probably benign
R2344:Fsip2	UTSW	2	82,820,257 (GRCm39)	missense	possibly damaging	0.71
R2377:Fsip2	UTSW	2	82,806,593 (GRCm39)	missense	probably benign	0.29
R2403:Fsip2	UTSW	2	82,811,064 (GRCm39)	missense	possibly damaging	0.53
R2441:Fsip2	UTSW	2	82,815,685 (GRCm39)	missense	possibly damaging	0.53
R2504:Fsip2	UTSW	2	82,809,954 (GRCm39)	missense	possibly damaging	0.86
R2510:Fsip2	UTSW	2	82,816,782 (GRCm39)	missense	probably benign
R2511:Fsip2	UTSW	2	82,816,782 (GRCm39)	missense	probably benign
R2511:Fsip2	UTSW	2	82,782,001 (GRCm39)	missense	probably damaging	1.00
R2512:Fsip2	UTSW	2	82,808,511 (GRCm39)	missense	probably benign	0.04
R2568:Fsip2	UTSW	2	82,820,775 (GRCm39)	missense	probably benign	0.14
R2656:Fsip2	UTSW	2	82,809,389 (GRCm39)	missense	possibly damaging	0.83
R2883:Fsip2	UTSW	2	82,821,868 (GRCm39)	missense	possibly damaging	0.86
R3417:Fsip2	UTSW	2	82,816,854 (GRCm39)	missense	possibly damaging	0.51
R3431:Fsip2	UTSW	2	82,822,354 (GRCm39)	missense	possibly damaging	0.85
R3441:Fsip2	UTSW	2	82,817,071 (GRCm39)	missense	probably benign	0.00
R3605:Fsip2	UTSW	2	82,815,253 (GRCm39)	missense	probably benign	0.28
R3620:Fsip2	UTSW	2	82,810,602 (GRCm39)	missense	probably benign	0.00
R3621:Fsip2	UTSW	2	82,810,602 (GRCm39)	missense	probably benign	0.00
R3726:Fsip2	UTSW	2	82,819,311 (GRCm39)	missense	possibly damaging	0.84
R3755:Fsip2	UTSW	2	82,808,561 (GRCm39)	missense	probably benign	0.26
R3789:Fsip2	UTSW	2	82,813,058 (GRCm39)	missense	probably damaging	0.96
R3836:Fsip2	UTSW	2	82,781,290 (GRCm39)	missense	probably damaging	1.00
R3844:Fsip2	UTSW	2	82,819,950 (GRCm39)	missense	possibly damaging	0.52
R3846:Fsip2	UTSW	2	82,816,759 (GRCm39)	missense	possibly damaging	0.52
R3861:Fsip2	UTSW	2	82,815,120 (GRCm39)	missense	probably damaging	0.98
R3981:Fsip2	UTSW	2	82,789,006 (GRCm39)	missense	probably benign	0.08
R4014:Fsip2	UTSW	2	82,813,862 (GRCm39)	missense	probably benign
R4042:Fsip2	UTSW	2	82,813,896 (GRCm39)	missense	probably benign	0.02
R4075:Fsip2	UTSW	2	82,813,245 (GRCm39)	missense	probably benign	0.26
R4154:Fsip2	UTSW	2	82,817,413 (GRCm39)	missense	possibly damaging	0.71
R4210:Fsip2	UTSW	2	82,805,493 (GRCm39)	missense	probably damaging	0.99
R4211:Fsip2	UTSW	2	82,805,493 (GRCm39)	missense	probably damaging	0.99
R4327:Fsip2	UTSW	2	82,817,403 (GRCm39)	missense	probably benign	0.25
R4332:Fsip2	UTSW	2	82,808,201 (GRCm39)	missense	probably benign	0.00
R4440:Fsip2	UTSW	2	82,821,550 (GRCm39)	missense	possibly damaging	0.85
R4454:Fsip2	UTSW	2	82,821,120 (GRCm39)	missense	possibly damaging	0.70
R4455:Fsip2	UTSW	2	82,821,120 (GRCm39)	missense	possibly damaging	0.70
R4457:Fsip2	UTSW	2	82,821,120 (GRCm39)	missense	possibly damaging	0.70
R4458:Fsip2	UTSW	2	82,821,120 (GRCm39)	missense	possibly damaging	0.70
R4540:Fsip2	UTSW	2	82,782,009 (GRCm39)	missense	probably benign
R4549:Fsip2	UTSW	2	82,819,972 (GRCm39)	missense	probably damaging	0.99
R4558:Fsip2	UTSW	2	82,815,297 (GRCm39)	missense	possibly damaging	0.73
R4573:Fsip2	UTSW	2	82,816,510 (GRCm39)	missense	possibly damaging	0.71
R4583:Fsip2	UTSW	2	82,809,017 (GRCm39)	missense	probably benign	0.33
R4618:Fsip2	UTSW	2	82,818,103 (GRCm39)	missense	probably benign
R4700:Fsip2	UTSW	2	82,817,373 (GRCm39)	missense	probably benign	0.32
R4716:Fsip2	UTSW	2	82,805,203 (GRCm39)	missense	probably damaging	0.96
R4739:Fsip2	UTSW	2	82,805,697 (GRCm39)	missense	possibly damaging	0.92
R4749:Fsip2	UTSW	2	82,819,629 (GRCm39)	missense	probably benign	0.06
R4791:Fsip2	UTSW	2	82,812,452 (GRCm39)	missense	possibly damaging	0.53
R4793:Fsip2	UTSW	2	82,818,044 (GRCm39)	nonsense	probably null
R4819:Fsip2	UTSW	2	82,818,786 (GRCm39)	missense	probably benign	0.06
R4832:Fsip2	UTSW	2	82,820,515 (GRCm39)	missense	possibly damaging	0.92
R4840:Fsip2	UTSW	2	82,815,815 (GRCm39)	missense	probably benign	0.26
R4840:Fsip2	UTSW	2	82,779,739 (GRCm39)	missense	probably benign	0.01
R4865:Fsip2	UTSW	2	82,821,295 (GRCm39)	missense	possibly damaging	0.86
R4876:Fsip2	UTSW	2	82,805,202 (GRCm39)	missense	possibly damaging	0.91
R4885:Fsip2	UTSW	2	82,818,438 (GRCm39)	missense	probably benign	0.02
R4911:Fsip2	UTSW	2	82,811,837 (GRCm39)	missense	possibly damaging	0.85
R4918:Fsip2	UTSW	2	82,824,114 (GRCm39)	missense	possibly damaging	0.51
R4936:Fsip2	UTSW	2	82,815,384 (GRCm39)	missense	probably benign	0.18
R4950:Fsip2	UTSW	2	82,807,758 (GRCm39)	missense	probably benign	0.03
R4950:Fsip2	UTSW	2	82,777,276 (GRCm39)	missense	probably damaging	0.97
R4959:Fsip2	UTSW	2	82,815,169 (GRCm39)	missense	probably benign	0.00
R4971:Fsip2	UTSW	2	82,816,222 (GRCm39)	missense	probably benign	0.38
R4973:Fsip2	UTSW	2	82,815,169 (GRCm39)	missense	probably benign	0.00
R4976:Fsip2	UTSW	2	82,818,535 (GRCm39)	missense	probably damaging	0.99
R5022:Fsip2	UTSW	2	82,809,773 (GRCm39)	missense	probably benign	0.33
R5027:Fsip2	UTSW	2	82,819,477 (GRCm39)	missense	possibly damaging	0.71
R5030:Fsip2	UTSW	2	82,818,836 (GRCm39)	missense	possibly damaging	0.85
R5048:Fsip2	UTSW	2	82,823,494 (GRCm39)	missense	probably damaging	0.97
R5096:Fsip2	UTSW	2	82,821,460 (GRCm39)	missense	probably benign	0.00
R5097:Fsip2	UTSW	2	82,822,329 (GRCm39)	missense	probably benign
R5119:Fsip2	UTSW	2	82,818,535 (GRCm39)	missense	probably damaging	0.99
R5138:Fsip2	UTSW	2	82,811,768 (GRCm39)	missense	probably benign	0.12
R5152:Fsip2	UTSW	2	82,808,916 (GRCm39)	missense	probably benign	0.43
R5174:Fsip2	UTSW	2	82,811,085 (GRCm39)	missense	probably benign	0.07
R5193:Fsip2	UTSW	2	82,813,338 (GRCm39)	missense	possibly damaging	0.53
R5245:Fsip2	UTSW	2	82,823,505 (GRCm39)	missense	probably benign	0.02
R5282:Fsip2	UTSW	2	82,808,925 (GRCm39)	missense	possibly damaging	0.61
R5323:Fsip2	UTSW	2	82,818,489 (GRCm39)	missense	possibly damaging	0.71
R5326:Fsip2	UTSW	2	82,812,207 (GRCm39)	missense	possibly damaging	0.84
R5378:Fsip2	UTSW	2	82,820,185 (GRCm39)	missense	possibly damaging	0.71
R5380:Fsip2	UTSW	2	82,805,742 (GRCm39)	missense	possibly damaging	0.91
R5396:Fsip2	UTSW	2	82,821,262 (GRCm39)	missense	probably benign	0.00
R5422:Fsip2	UTSW	2	82,812,572 (GRCm39)	missense	probably benign	0.00
R5481:Fsip2	UTSW	2	82,810,230 (GRCm39)	missense	probably benign	0.26
R5482:Fsip2	UTSW	2	82,815,654 (GRCm39)	missense	possibly damaging	0.80
R5513:Fsip2	UTSW	2	82,815,542 (GRCm39)	missense	possibly damaging	0.72
R5513:Fsip2	UTSW	2	82,781,256 (GRCm39)	missense	probably benign	0.07
R5513:Fsip2	UTSW	2	82,781,252 (GRCm39)	missense	probably damaging	1.00
R5536:Fsip2	UTSW	2	82,817,403 (GRCm39)	missense	probably benign	0.25
R5542:Fsip2	UTSW	2	82,812,207 (GRCm39)	missense	possibly damaging	0.84
R5553:Fsip2	UTSW	2	82,793,090 (GRCm39)	missense	probably benign
R5568:Fsip2	UTSW	2	82,816,908 (GRCm39)	missense	probably benign	0.25
R5581:Fsip2	UTSW	2	82,828,472 (GRCm39)	missense	possibly damaging	0.84
R5664:Fsip2	UTSW	2	82,818,439 (GRCm39)	missense	probably benign	0.05
R5672:Fsip2	UTSW	2	82,817,838 (GRCm39)	nonsense	probably null
R5712:Fsip2	UTSW	2	82,839,192 (GRCm39)	missense	possibly damaging	0.73
R5762:Fsip2	UTSW	2	82,808,260 (GRCm39)	missense	probably benign	0.33
R5772:Fsip2	UTSW	2	82,815,084 (GRCm39)	missense	probably benign
R5881:Fsip2	UTSW	2	82,814,785 (GRCm39)	missense	possibly damaging	0.72
R5919:Fsip2	UTSW	2	82,822,953 (GRCm39)	missense	possibly damaging	0.71
R5920:Fsip2	UTSW	2	82,818,852 (GRCm39)	nonsense	probably null
R5934:Fsip2	UTSW	2	82,817,092 (GRCm39)	missense	possibly damaging	0.86
R5938:Fsip2	UTSW	2	82,807,835 (GRCm39)	missense	probably benign	0.00
R5974:Fsip2	UTSW	2	82,793,657 (GRCm39)	missense	possibly damaging	0.68
R5991:Fsip2	UTSW	2	82,820,812 (GRCm39)	missense	probably benign	0.28
R6019:Fsip2	UTSW	2	82,818,283 (GRCm39)	missense	possibly damaging	0.52
R6020:Fsip2	UTSW	2	82,822,471 (GRCm39)	missense	probably damaging	0.99
R6056:Fsip2	UTSW	2	82,816,017 (GRCm39)	missense	probably benign	0.01
R6057:Fsip2	UTSW	2	82,809,777 (GRCm39)	missense	probably damaging	0.99
R6139:Fsip2	UTSW	2	82,821,388 (GRCm39)	missense	possibly damaging	0.85
R6145:Fsip2	UTSW	2	82,824,112 (GRCm39)	missense	possibly damaging	0.71
R6160:Fsip2	UTSW	2	82,818,289 (GRCm39)	nonsense	probably null
R6161:Fsip2	UTSW	2	82,817,601 (GRCm39)	missense	possibly damaging	0.80
R6166:Fsip2	UTSW	2	82,811,071 (GRCm39)	missense	probably benign	0.00
R6187:Fsip2	UTSW	2	82,812,798 (GRCm39)	missense	probably benign	0.33
R6196:Fsip2	UTSW	2	82,820,227 (GRCm39)	missense	possibly damaging	0.71
R6217:Fsip2	UTSW	2	82,818,762 (GRCm39)	missense	possibly damaging	0.93
R6276:Fsip2	UTSW	2	82,810,785 (GRCm39)	missense	possibly damaging	0.91
R6278:Fsip2	UTSW	2	82,819,242 (GRCm39)	missense	probably benign	0.16
R6349:Fsip2	UTSW	2	82,823,416 (GRCm39)	missense	probably benign	0.05
R6351:Fsip2	UTSW	2	82,823,028 (GRCm39)	missense	possibly damaging	0.51
R6401:Fsip2	UTSW	2	82,820,430 (GRCm39)	missense	possibly damaging	0.71
R6404:Fsip2	UTSW	2	82,820,430 (GRCm39)	missense	possibly damaging	0.71
R6405:Fsip2	UTSW	2	82,820,430 (GRCm39)	missense	possibly damaging	0.71
R6437:Fsip2	UTSW	2	82,813,836 (GRCm39)	missense	possibly damaging	0.73
R6478:Fsip2	UTSW	2	82,820,430 (GRCm39)	missense	possibly damaging	0.71
R6479:Fsip2	UTSW	2	82,820,430 (GRCm39)	missense	possibly damaging	0.71
R6480:Fsip2	UTSW	2	82,820,430 (GRCm39)	missense	possibly damaging	0.71
R6481:Fsip2	UTSW	2	82,820,430 (GRCm39)	missense	possibly damaging	0.71
R6521:Fsip2	UTSW	2	82,820,430 (GRCm39)	missense	possibly damaging	0.71
R6529:Fsip2	UTSW	2	82,812,657 (GRCm39)	missense	probably benign
R6621:Fsip2	UTSW	2	82,820,158 (GRCm39)	missense	possibly damaging	0.93
R6639:Fsip2	UTSW	2	82,813,571 (GRCm39)	missense	possibly damaging	0.85
R6649:Fsip2	UTSW	2	82,798,161 (GRCm39)	missense	possibly damaging	0.83
R6714:Fsip2	UTSW	2	82,820,430 (GRCm39)	missense	possibly damaging	0.71
R6714:Fsip2	UTSW	2	82,809,878 (GRCm39)	missense	probably benign	0.01
R6749:Fsip2	UTSW	2	82,808,738 (GRCm39)	missense	possibly damaging	0.85
R6765:Fsip2	UTSW	2	82,816,776 (GRCm39)	missense	probably benign
R6790:Fsip2	UTSW	2	82,821,283 (GRCm39)	missense	possibly damaging	0.53
R6793:Fsip2	UTSW	2	82,819,838 (GRCm39)	missense	probably benign	0.43
R6795:Fsip2	UTSW	2	82,811,303 (GRCm39)	missense	probably benign	0.08
R6818:Fsip2	UTSW	2	82,815,544 (GRCm39)	missense	probably benign	0.04
R6844:Fsip2	UTSW	2	82,813,969 (GRCm39)	missense	possibly damaging	0.72
R6848:Fsip2	UTSW	2	82,813,131 (GRCm39)	missense	probably benign	0.26
R6945:Fsip2	UTSW	2	82,823,184 (GRCm39)	missense	probably benign	0.16
R6950:Fsip2	UTSW	2	82,816,332 (GRCm39)	missense	probably benign	0.03
R6951:Fsip2	UTSW	2	82,812,293 (GRCm39)	missense	possibly damaging	0.68
R6974:Fsip2	UTSW	2	82,809,061 (GRCm39)	missense	probably damaging	0.96
R6987:Fsip2	UTSW	2	82,778,630 (GRCm39)	nonsense	probably null
R6989:Fsip2	UTSW	2	82,807,298 (GRCm39)	missense	probably benign	0.00
R7001:Fsip2	UTSW	2	82,817,269 (GRCm39)	missense	probably damaging	1.00
R7002:Fsip2	UTSW	2	82,819,687 (GRCm39)	missense	possibly damaging	0.86
R7016:Fsip2	UTSW	2	82,820,979 (GRCm39)	missense	probably benign	0.25
R7066:Fsip2	UTSW	2	82,821,235 (GRCm39)	missense	possibly damaging	0.86
R7067:Fsip2	UTSW	2	82,811,078 (GRCm39)	missense	possibly damaging	0.85
R7077:Fsip2	UTSW	2	82,813,496 (GRCm39)	missense	probably benign	0.18
R7099:Fsip2	UTSW	2	82,817,968 (GRCm39)	missense	probably benign
R7126:Fsip2	UTSW	2	82,813,485 (GRCm39)	missense	possibly damaging	0.53
R7156:Fsip2	UTSW	2	82,813,085 (GRCm39)	missense	probably benign	0.00
R7165:Fsip2	UTSW	2	82,811,541 (GRCm39)	missense	possibly damaging	0.77
R7171:Fsip2	UTSW	2	82,816,571 (GRCm39)	nonsense	probably null
R7189:Fsip2	UTSW	2	82,823,581 (GRCm39)	missense	possibly damaging	0.92
R7217:Fsip2	UTSW	2	82,819,412 (GRCm39)	missense	possibly damaging	0.85
R7222:Fsip2	UTSW	2	82,814,015 (GRCm39)	missense	probably benign
R7228:Fsip2	UTSW	2	82,822,651 (GRCm39)	missense	possibly damaging	0.93
R7238:Fsip2	UTSW	2	82,812,484 (GRCm39)	missense	possibly damaging	0.72
R7244:Fsip2	UTSW	2	82,823,607 (GRCm39)	missense	possibly damaging	0.92
R7251:Fsip2	UTSW	2	82,809,425 (GRCm39)	missense	possibly damaging	0.95
R7259:Fsip2	UTSW	2	82,812,474 (GRCm39)	missense	possibly damaging	0.85
R7291:Fsip2	UTSW	2	82,810,863 (GRCm39)	missense	possibly damaging	0.91
R7316:Fsip2	UTSW	2	82,820,035 (GRCm39)	missense	possibly damaging	0.93
R7323:Fsip2	UTSW	2	82,819,860 (GRCm39)	missense	probably benign	0.07
R7335:Fsip2	UTSW	2	82,813,462 (GRCm39)	missense	probably benign
R7343:Fsip2	UTSW	2	82,809,711 (GRCm39)	missense	probably benign	0.07
R7346:Fsip2	UTSW	2	82,828,524 (GRCm39)	missense	probably benign	0.00
R7389:Fsip2	UTSW	2	82,819,140 (GRCm39)	missense	possibly damaging	0.51
R7391:Fsip2	UTSW	2	82,820,663 (GRCm39)	missense	possibly damaging	0.70
R7397:Fsip2	UTSW	2	82,815,601 (GRCm39)	missense	possibly damaging	0.53
R7426:Fsip2	UTSW	2	82,810,441 (GRCm39)	missense	probably damaging	0.98
R7450:Fsip2	UTSW	2	82,782,024 (GRCm39)	missense	probably benign	0.30
R7538:Fsip2	UTSW	2	82,818,894 (GRCm39)	missense	possibly damaging	0.86
R7542:Fsip2	UTSW	2	82,815,196 (GRCm39)	missense	possibly damaging	0.96
R7549:Fsip2	UTSW	2	82,824,337 (GRCm39)	missense	probably damaging	0.99
R7564:Fsip2	UTSW	2	82,819,361 (GRCm39)	missense	probably benign	0.02
R7565:Fsip2	UTSW	2	82,779,856 (GRCm39)	missense	probably damaging	0.97
R7583:Fsip2	UTSW	2	82,805,585 (GRCm39)	missense	probably benign	0.12
R7641:Fsip2	UTSW	2	82,817,256 (GRCm39)	nonsense	probably null
R7655:Fsip2	UTSW	2	82,807,886 (GRCm39)	missense	possibly damaging	0.91
R7656:Fsip2	UTSW	2	82,807,886 (GRCm39)	missense	possibly damaging	0.91
R7665:Fsip2	UTSW	2	82,812,149 (GRCm39)	missense	probably benign	0.03
R7672:Fsip2	UTSW	2	82,820,455 (GRCm39)	missense	possibly damaging	0.93
R7764:Fsip2	UTSW	2	82,811,252 (GRCm39)	missense	possibly damaging	0.93
R7790:Fsip2	UTSW	2	82,818,723 (GRCm39)	missense	probably benign
R7811:Fsip2	UTSW	2	82,828,797 (GRCm39)	missense	possibly damaging	0.93
R7838:Fsip2	UTSW	2	82,807,044 (GRCm39)	missense	probably benign	0.00
R7873:Fsip2	UTSW	2	82,779,856 (GRCm39)	missense	probably damaging	0.97
R7902:Fsip2	UTSW	2	82,808,168 (GRCm39)	missense	possibly damaging	0.72
R7920:Fsip2	UTSW	2	82,781,365 (GRCm39)	missense	possibly damaging	0.94
R7959:Fsip2	UTSW	2	82,816,120 (GRCm39)	missense	possibly damaging	0.51
R8009:Fsip2	UTSW	2	82,818,793 (GRCm39)	missense	possibly damaging	0.85
R8031:Fsip2	UTSW	2	82,817,235 (GRCm39)	missense	probably benign
R8034:Fsip2	UTSW	2	82,819,699 (GRCm39)	missense	possibly damaging	0.92
R8037:Fsip2	UTSW	2	82,816,322 (GRCm39)	missense	possibly damaging	0.72
R8110:Fsip2	UTSW	2	82,789,017 (GRCm39)	missense	probably benign	0.00
R8117:Fsip2	UTSW	2	82,823,296 (GRCm39)	missense	possibly damaging	0.86
R8138:Fsip2	UTSW	2	82,806,141 (GRCm39)	missense	possibly damaging	0.83
R8175:Fsip2	UTSW	2	82,818,021 (GRCm39)	missense	probably benign	0.16
R8175:Fsip2	UTSW	2	82,815,088 (GRCm39)	missense	probably benign	0.06
R8182:Fsip2	UTSW	2	82,806,951 (GRCm39)	missense	probably damaging	0.99
R8206:Fsip2	UTSW	2	82,820,808 (GRCm39)	missense	possibly damaging	0.85
R8229:Fsip2	UTSW	2	82,808,487 (GRCm39)	missense	possibly damaging	0.63
R8239:Fsip2	UTSW	2	82,819,687 (GRCm39)	missense	possibly damaging	0.71
R8245:Fsip2	UTSW	2	82,811,346 (GRCm39)	missense	possibly damaging	0.79
R8303:Fsip2	UTSW	2	82,818,724 (GRCm39)	missense	probably benign	0.00
R8336:Fsip2	UTSW	2	82,821,099 (GRCm39)	missense	possibly damaging	0.53
R8347:Fsip2	UTSW	2	82,818,198 (GRCm39)	missense	probably benign	0.16
R8351:Fsip2	UTSW	2	82,822,239 (GRCm39)	missense	possibly damaging	0.73
R8352:Fsip2	UTSW	2	82,814,937 (GRCm39)	missense	probably benign
R8419:Fsip2	UTSW	2	82,808,963 (GRCm39)	missense	probably damaging	0.96
R8431:Fsip2	UTSW	2	82,811,910 (GRCm39)	missense	probably damaging	1.00
R8439:Fsip2	UTSW	2	82,807,430 (GRCm39)	missense	probably benign	0.24
R8452:Fsip2	UTSW	2	82,814,937 (GRCm39)	missense	probably benign
R8459:Fsip2	UTSW	2	82,810,022 (GRCm39)	missense	possibly damaging	0.95
R8465:Fsip2	UTSW	2	82,810,284 (GRCm39)	missense	probably benign	0.26
R8473:Fsip2	UTSW	2	82,777,336 (GRCm39)	missense	probably damaging	0.99
R8703:Fsip2	UTSW	2	82,821,871 (GRCm39)	missense	probably damaging	0.98
R8711:Fsip2	UTSW	2	82,815,246 (GRCm39)	missense	possibly damaging	0.53
R8713:Fsip2	UTSW	2	82,811,453 (GRCm39)	missense	probably damaging	1.00
R8789:Fsip2	UTSW	2	82,815,822 (GRCm39)	missense	possibly damaging	0.73
R8805:Fsip2	UTSW	2	82,813,453 (GRCm39)	missense	possibly damaging	0.46
R8840:Fsip2	UTSW	2	82,821,606 (GRCm39)	missense	probably benign	0.03
R8855:Fsip2	UTSW	2	82,810,521 (GRCm39)	missense	probably benign	0.04
R8866:Fsip2	UTSW	2	82,810,521 (GRCm39)	missense	probably benign	0.04
R8875:Fsip2	UTSW	2	82,820,782 (GRCm39)	missense	possibly damaging	0.95
R8883:Fsip2	UTSW	2	82,809,524 (GRCm39)	missense	possibly damaging	0.68
R8903:Fsip2	UTSW	2	82,807,681 (GRCm39)	missense	possibly damaging	0.83
R8907:Fsip2	UTSW	2	82,816,984 (GRCm39)	missense	probably benign	0.20
R8912:Fsip2	UTSW	2	82,810,938 (GRCm39)	missense	probably benign
R8926:Fsip2	UTSW	2	82,823,927 (GRCm39)	missense	possibly damaging	0.84
R8991:Fsip2	UTSW	2	82,815,370 (GRCm39)	missense	probably benign	0.33
R9014:Fsip2	UTSW	2	82,806,898 (GRCm39)	missense	probably benign	0.32
R9014:Fsip2	UTSW	2	82,817,075 (GRCm39)	missense	possibly damaging	0.71
R9039:Fsip2	UTSW	2	82,828,545 (GRCm39)	missense	probably benign	0.32
R9054:Fsip2	UTSW	2	82,806,180 (GRCm39)	missense	possibly damaging	0.68
R9114:Fsip2	UTSW	2	82,807,301 (GRCm39)	missense	probably benign	0.00
R9124:Fsip2	UTSW	2	82,816,103 (GRCm39)	missense	probably benign	0.00
R9131:Fsip2	UTSW	2	82,813,170 (GRCm39)	missense	probably benign
R9149:Fsip2	UTSW	2	82,812,374 (GRCm39)	missense	possibly damaging	0.86
R9180:Fsip2	UTSW	2	82,815,574 (GRCm39)	missense	possibly damaging	0.96
R9192:Fsip2	UTSW	2	82,817,844 (GRCm39)	missense	probably benign	0.06
R9216:Fsip2	UTSW	2	82,820,425 (GRCm39)	missense	probably damaging	0.99
R9218:Fsip2	UTSW	2	82,823,062 (GRCm39)	missense	probably damaging	0.97
R9222:Fsip2	UTSW	2	82,815,958 (GRCm39)	missense	probably benign	0.00
R9262:Fsip2	UTSW	2	82,807,662 (GRCm39)	missense	probably benign	0.00
R9340:Fsip2	UTSW	2	82,818,604 (GRCm39)	missense	possibly damaging	0.71
R9342:Fsip2	UTSW	2	82,818,747 (GRCm39)	missense	possibly damaging	0.71
R9368:Fsip2	UTSW	2	82,811,039 (GRCm39)	missense	possibly damaging	0.68
R9372:Fsip2	UTSW	2	82,822,756 (GRCm39)	missense	possibly damaging	0.71
R9385:Fsip2	UTSW	2	82,819,793 (GRCm39)	missense	possibly damaging	0.84
R9432:Fsip2	UTSW	2	82,805,907 (GRCm39)	missense	probably damaging	0.98
R9434:Fsip2	UTSW	2	82,816,702 (GRCm39)	missense	possibly damaging	0.71
R9445:Fsip2	UTSW	2	82,806,132 (GRCm39)	missense	probably damaging	0.99
R9472:Fsip2	UTSW	2	82,817,285 (GRCm39)	missense	possibly damaging	0.85
R9496:Fsip2	UTSW	2	82,793,062 (GRCm39)	missense	probably benign
R9523:Fsip2	UTSW	2	82,807,972 (GRCm39)	missense	probably damaging	0.99
R9567:Fsip2	UTSW	2	82,798,173 (GRCm39)	missense	probably benign
R9636:Fsip2	UTSW	2	82,820,563 (GRCm39)	missense	possibly damaging	0.52
R9643:Fsip2	UTSW	2	82,821,984 (GRCm39)	missense	possibly damaging	0.53
R9680:Fsip2	UTSW	2	82,819,272 (GRCm39)	missense	probably benign	0.32
R9695:Fsip2	UTSW	2	82,806,226 (GRCm39)	missense	probably benign
R9705:Fsip2	UTSW	2	82,823,634 (GRCm39)	missense	probably benign
R9739:Fsip2	UTSW	2	82,823,896 (GRCm39)	missense	possibly damaging	0.71
R9751:Fsip2	UTSW	2	82,818,241 (GRCm39)	missense	probably benign	0.00
R9761:Fsip2	UTSW	2	82,821,994 (GRCm39)	missense	probably benign	0.00
R9798:Fsip2	UTSW	2	82,810,225 (GRCm39)	nonsense	probably null
RF003:Fsip2	UTSW	2	82,821,865 (GRCm39)	missense	probably benign	0.02
RF005:Fsip2	UTSW	2	82,822,876 (GRCm39)	missense	probably benign	0.04
RF008:Fsip2	UTSW	2	82,808,184 (GRCm39)	missense	probably benign
RF028:Fsip2	UTSW	2	82,824,352 (GRCm39)	frame shift	probably null
RF029:Fsip2	UTSW	2	82,824,352 (GRCm39)	frame shift	probably null
RF036:Fsip2	UTSW	2	82,814,707 (GRCm39)	critical splice acceptor site	probably benign
RF038:Fsip2	UTSW	2	82,824,352 (GRCm39)	frame shift	probably null
RF062:Fsip2	UTSW	2	82,814,707 (GRCm39)	critical splice acceptor site	probably benign
X0018:Fsip2	UTSW	2	82,812,851 (GRCm39)	nonsense	probably null
X0020:Fsip2	UTSW	2	82,781,364 (GRCm39)	missense	probably damaging	1.00
X0025:Fsip2	UTSW	2	82,785,290 (GRCm39)	missense	possibly damaging	0.70
X0027:Fsip2	UTSW	2	82,807,122 (GRCm39)	missense	probably benign	0.35
X0066:Fsip2	UTSW	2	82,817,807 (GRCm39)	missense	possibly damaging	0.51
Z1088:Fsip2	UTSW	2	82,818,978 (GRCm39)	missense	possibly damaging	0.85
Z1088:Fsip2	UTSW	2	82,817,997 (GRCm39)	missense	possibly damaging	0.86
Z1088:Fsip2	UTSW	2	82,805,792 (GRCm39)	missense	probably damaging	0.96
Z1176:Fsip2	UTSW	2	82,820,009 (GRCm39)	missense	probably benign	0.02
Z1177:Fsip2	UTSW	2	82,814,868 (GRCm39)	missense	probably damaging	0.98
Z1177:Fsip2	UTSW	2	82,777,304 (GRCm39)	missense	probably damaging	0.99
Z1177:Fsip2	UTSW	2	82,817,547 (GRCm39)	missense	possibly damaging	0.71

Predicted Primers

PCR Primer
(F):5'- ATGAACCCACCCGATTGTAAG -3'
(R):5'- CCACTAAAATGGGCACGTGAG -3'

Sequencing Primer
(F):5'- CACCCGATTGTAAGACAGATAAAAAG -3'
(R):5'- CGTGAGAGTGAAAACACATTTAATTG -3'

Posted On

2014-08-25