Incidental Mutation 'R2006:Tdrd6'
| ID |
225633 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Tdrd6
|
| Ensembl Gene |
ENSMUSG00000040140 |
| Gene Name |
tudor domain containing 6 |
| Synonyms |
|
| MMRRC Submission |
040015-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R2006 (G1)
|
| Quality Score |
225 |
|
Status
|
Not validated
|
| Chromosome |
17 |
| Chromosomal Location |
43926226-43941190 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to G
at 43939546 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Phenylalanine to Leucine
at position 501
(F501L)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000131277
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000045717]
[ENSMUST00000168073]
|
| AlphaFold |
no structure available at present |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000045717
AA Change: F501L
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000035338
Gene: ENSMUSG00000040140
AA Change: F501L
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:TUDOR
|
14 |
133 |
9.9e-9 |
PFAM |
|
low complexity region
|
166 |
187 |
N/A |
INTRINSIC |
|
TUDOR
|
308 |
366 |
1.14e-2 |
SMART |
|
low complexity region
|
452 |
463 |
N/A |
INTRINSIC |
|
TUDOR
|
541 |
597 |
2.68e-8 |
SMART |
|
TUDOR
|
817 |
877 |
2.56e-5 |
SMART |
|
TUDOR
|
1037 |
1090 |
5.36e-8 |
SMART |
|
TUDOR
|
1357 |
1415 |
2.19e-13 |
SMART |
|
TUDOR
|
1569 |
1628 |
3.1e-13 |
SMART |
|
low complexity region
|
1826 |
1842 |
N/A |
INTRINSIC |
|
low complexity region
|
1866 |
1876 |
N/A |
INTRINSIC |
|
TUDOR
|
2026 |
2083 |
9.45e-1 |
SMART |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000168073
AA Change: F501L
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000131277
Gene: ENSMUSG00000040140
AA Change: F501L
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:TUDOR
|
12 |
133 |
7.2e-9 |
PFAM |
|
low complexity region
|
166 |
187 |
N/A |
INTRINSIC |
|
TUDOR
|
308 |
366 |
1.14e-2 |
SMART |
|
low complexity region
|
452 |
463 |
N/A |
INTRINSIC |
|
TUDOR
|
541 |
597 |
2.68e-8 |
SMART |
|
TUDOR
|
817 |
877 |
2.56e-5 |
SMART |
|
TUDOR
|
1037 |
1090 |
5.36e-8 |
SMART |
|
TUDOR
|
1357 |
1415 |
2.19e-13 |
SMART |
|
TUDOR
|
1569 |
1628 |
3.1e-13 |
SMART |
|
low complexity region
|
1826 |
1842 |
N/A |
INTRINSIC |
|
low complexity region
|
1866 |
1876 |
N/A |
INTRINSIC |
|
TUDOR
|
2027 |
2084 |
9.45e-1 |
SMART |
|
| Coding Region Coverage |
- 1x: 99.2%
- 3x: 98.5%
- 10x: 96.9%
- 20x: 94.2%
|
| Validation Efficiency |
|
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a tudor domain-containing protein and component of the chromatoid body, a type of ribonucleoprotein granule present in male germ cells. Studies in rodents have demonstrated a role for the encoded protein in spermiogenesis and the nonsense mediated decay (NMD) pathway. This protein is a major autoantigen in human patients with autoimmune polyendocrine syndrome type 1 (APS1). [provided by RefSeq, Oct 2016]
PHENOTYPE: Mice homozygous for a null allele exhibit male fertility associated with arrested spermatogenesis. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 97 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Abca5 |
A |
T |
11: 110,204,275 (GRCm39) |
F333L |
probably benign |
Het |
| Abcc2 |
T |
A |
19: 43,793,500 (GRCm39) |
F384Y |
probably damaging |
Het |
| Acr |
C |
T |
15: 89,458,404 (GRCm39) |
P362S |
probably benign |
Het |
| Acss3 |
T |
C |
10: 106,798,871 (GRCm39) |
D484G |
possibly damaging |
Het |
| Actrt1 |
A |
G |
X: 45,418,593 (GRCm39) |
T203A |
probably benign |
Het |
| Agtpbp1 |
A |
T |
13: 59,648,135 (GRCm39) |
C562S |
probably benign |
Het |
| Ahnak |
A |
G |
19: 8,984,439 (GRCm39) |
K1908E |
probably damaging |
Het |
| Amph |
G |
A |
13: 19,326,198 (GRCm39) |
V643M |
probably damaging |
Het |
| Apaf1 |
A |
T |
10: 90,897,634 (GRCm39) |
I283N |
probably damaging |
Het |
| Bbx |
G |
A |
16: 50,044,758 (GRCm39) |
T493M |
possibly damaging |
Het |
| Best2 |
C |
T |
8: 85,739,818 (GRCm39) |
|
probably null |
Het |
| C4bp |
C |
A |
1: 130,575,769 (GRCm39) |
E75* |
probably null |
Het |
| Calr3 |
A |
T |
8: 73,188,695 (GRCm39) |
V144D |
probably damaging |
Het |
| Capn1 |
C |
T |
19: 6,041,613 (GRCm39) |
G632D |
probably damaging |
Het |
| Catsper2 |
C |
A |
2: 121,236,838 (GRCm39) |
E270* |
probably null |
Het |
| Ccdc110 |
A |
T |
8: 46,396,349 (GRCm39) |
I747F |
probably damaging |
Het |
| Ccdc15 |
T |
A |
9: 37,226,768 (GRCm39) |
D389V |
possibly damaging |
Het |
| Cd226 |
A |
G |
18: 89,265,435 (GRCm39) |
I125V |
probably benign |
Het |
| Crb2 |
A |
T |
2: 37,673,446 (GRCm39) |
D114V |
probably damaging |
Het |
| Crebbp |
TTGCTGCTGCTGCTGCTG |
TTGCTGCTGCTGCTG |
16: 3,902,617 (GRCm39) |
|
probably benign |
Het |
| Crebrf |
T |
C |
17: 26,961,857 (GRCm39) |
V318A |
possibly damaging |
Het |
| Dab1 |
T |
C |
4: 104,462,522 (GRCm39) |
I32T |
probably damaging |
Het |
| Daw1 |
T |
C |
1: 83,169,066 (GRCm39) |
V181A |
probably damaging |
Het |
| Dlg2 |
G |
A |
7: 91,614,825 (GRCm39) |
E255K |
possibly damaging |
Het |
| Dnah10 |
T |
A |
5: 124,906,651 (GRCm39) |
D4170E |
possibly damaging |
Het |
| Dnah12 |
A |
G |
14: 26,536,416 (GRCm39) |
T2111A |
possibly damaging |
Het |
| Dock10 |
T |
C |
1: 80,527,506 (GRCm39) |
Y1081C |
possibly damaging |
Het |
| Dscam |
T |
C |
16: 96,621,112 (GRCm39) |
Y532C |
probably damaging |
Het |
| Fam83c |
T |
C |
2: 155,672,223 (GRCm39) |
D404G |
probably benign |
Het |
| Fam83g |
A |
G |
11: 61,593,801 (GRCm39) |
N445S |
possibly damaging |
Het |
| Ghr |
C |
T |
15: 3,357,464 (GRCm39) |
C268Y |
probably damaging |
Het |
| Gm8444 |
T |
C |
15: 81,727,775 (GRCm39) |
|
probably benign |
Het |
| Gp6 |
T |
A |
7: 4,387,988 (GRCm39) |
K160N |
probably benign |
Het |
| Grm3 |
T |
C |
5: 9,639,793 (GRCm39) |
Y84C |
possibly damaging |
Het |
| Gtf3c2 |
C |
A |
5: 31,325,440 (GRCm39) |
G450C |
probably damaging |
Het |
| Icosl |
A |
T |
10: 77,907,787 (GRCm39) |
M116L |
possibly damaging |
Het |
| Il31ra |
T |
G |
13: 112,666,890 (GRCm39) |
Y396S |
probably damaging |
Het |
| Insig1 |
A |
G |
5: 28,276,464 (GRCm39) |
N10S |
probably benign |
Het |
| Kcnh2 |
C |
A |
5: 24,531,568 (GRCm39) |
G448C |
probably damaging |
Het |
| L1td1 |
C |
T |
4: 98,621,726 (GRCm39) |
S96L |
possibly damaging |
Het |
| Mapre3 |
A |
T |
5: 31,019,168 (GRCm39) |
N4I |
probably damaging |
Het |
| Mblac2 |
T |
A |
13: 81,859,860 (GRCm39) |
D70E |
probably benign |
Het |
| Mki67 |
T |
A |
7: 135,300,238 (GRCm39) |
K1599* |
probably null |
Het |
| Mpg |
A |
G |
11: 32,181,840 (GRCm39) |
I283V |
probably benign |
Het |
| Mrtfb |
G |
T |
16: 13,199,440 (GRCm39) |
E98* |
probably null |
Het |
| Mybpc1 |
C |
A |
10: 88,381,921 (GRCm39) |
A576S |
probably damaging |
Het |
| Myo1h |
T |
G |
5: 114,499,140 (GRCm39) |
V129G |
probably damaging |
Het |
| Nars1 |
A |
T |
18: 64,638,099 (GRCm39) |
V285E |
probably damaging |
Het |
| Nbas |
T |
A |
12: 13,464,742 (GRCm39) |
|
probably null |
Het |
| Neb |
T |
C |
2: 52,089,456 (GRCm39) |
D5172G |
probably null |
Het |
| Npbwr1 |
T |
A |
1: 5,986,570 (GRCm39) |
S315C |
probably damaging |
Het |
| Nyap1 |
T |
C |
5: 137,733,953 (GRCm39) |
H360R |
possibly damaging |
Het |
| Nyx |
A |
G |
X: 13,352,974 (GRCm39) |
E276G |
probably damaging |
Het |
| Or10ag59 |
T |
A |
2: 87,405,536 (GRCm39) |
M36K |
probably benign |
Het |
| Or1e1 |
G |
T |
11: 73,245,518 (GRCm39) |
C313F |
probably benign |
Het |
| Or2l13b |
A |
G |
16: 19,349,455 (GRCm39) |
Y72H |
probably benign |
Het |
| Or2w6 |
T |
C |
13: 21,842,642 (GRCm39) |
T284A |
possibly damaging |
Het |
| Or4c1 |
A |
G |
2: 89,133,160 (GRCm39) |
Y259H |
possibly damaging |
Het |
| Or4c118 |
A |
T |
2: 88,975,241 (GRCm39) |
V42E |
probably benign |
Het |
| Or5v1b |
C |
T |
17: 37,841,597 (GRCm39) |
S243F |
probably damaging |
Het |
| Or7e174 |
A |
T |
9: 20,012,165 (GRCm39) |
M37L |
probably benign |
Het |
| Or7g16 |
G |
A |
9: 18,726,801 (GRCm39) |
S263L |
probably benign |
Het |
| Or8g23 |
T |
A |
9: 38,971,729 (GRCm39) |
T78S |
probably damaging |
Het |
| Paf1 |
C |
A |
7: 28,095,193 (GRCm39) |
|
probably null |
Het |
| Pcsk5 |
T |
C |
19: 17,455,280 (GRCm39) |
D1050G |
probably benign |
Het |
| Pgap1 |
A |
G |
1: 54,590,220 (GRCm39) |
S73P |
possibly damaging |
Het |
| Phtf1 |
G |
A |
3: 103,911,799 (GRCm39) |
|
probably null |
Het |
| Pik3c2b |
G |
T |
1: 132,994,282 (GRCm39) |
R82L |
probably damaging |
Het |
| Pik3ca |
T |
C |
3: 32,504,206 (GRCm39) |
L632P |
probably damaging |
Het |
| Plau |
G |
T |
14: 20,888,760 (GRCm39) |
|
probably null |
Het |
| Pld4 |
A |
T |
12: 112,734,923 (GRCm39) |
Q460L |
possibly damaging |
Het |
| Prdm2 |
T |
A |
4: 142,858,447 (GRCm39) |
Q1614H |
possibly damaging |
Het |
| Ptprq |
C |
T |
10: 107,502,407 (GRCm39) |
G837D |
probably damaging |
Het |
| Rad9b |
A |
G |
5: 122,477,842 (GRCm39) |
V178A |
possibly damaging |
Het |
| Rfc1 |
G |
T |
5: 65,468,397 (GRCm39) |
Y105* |
probably null |
Het |
| Sardh |
G |
A |
2: 27,118,351 (GRCm39) |
R460C |
probably damaging |
Het |
| Scn5a |
C |
A |
9: 119,365,546 (GRCm39) |
R367L |
probably damaging |
Het |
| Sdcbp |
A |
T |
4: 6,386,536 (GRCm39) |
I137L |
probably benign |
Het |
| Shmt2 |
A |
G |
10: 127,355,029 (GRCm39) |
V273A |
probably benign |
Het |
| Slc5a9 |
G |
T |
4: 111,737,423 (GRCm39) |
P612H |
probably benign |
Het |
| Slitrk4 |
TTGT |
TT |
X: 63,314,294 (GRCm39) |
|
probably null |
Het |
| Slitrk4 |
TG |
T |
X: 63,314,295 (GRCm39) |
|
probably null |
Het |
| Spata1 |
A |
T |
3: 146,199,438 (GRCm39) |
S9T |
probably benign |
Het |
| Syn3 |
T |
C |
10: 85,909,097 (GRCm39) |
T328A |
probably benign |
Het |
| Tekt5 |
T |
C |
16: 10,213,070 (GRCm39) |
I72V |
probably benign |
Het |
| Ticrr |
T |
C |
7: 79,343,821 (GRCm39) |
S1229P |
possibly damaging |
Het |
| Tlr6 |
T |
C |
5: 65,110,748 (GRCm39) |
S720G |
probably damaging |
Het |
| Tmem156 |
T |
A |
5: 65,237,294 (GRCm39) |
D87V |
probably damaging |
Het |
| Togaram1 |
T |
A |
12: 65,065,914 (GRCm39) |
D1639E |
probably damaging |
Het |
| Ucn2 |
A |
G |
9: 108,815,430 (GRCm39) |
K64R |
probably benign |
Het |
| Vmn2r57 |
T |
A |
7: 41,098,001 (GRCm39) |
Y22F |
probably benign |
Het |
| Vwa1 |
T |
C |
4: 155,855,307 (GRCm39) |
T269A |
probably benign |
Het |
| Washc5 |
A |
G |
15: 59,213,004 (GRCm39) |
L892P |
possibly damaging |
Het |
| Wdr20 |
T |
C |
12: 110,760,002 (GRCm39) |
V296A |
probably damaging |
Het |
| Xxylt1 |
A |
T |
16: 30,869,586 (GRCm39) |
H171Q |
probably damaging |
Het |
| Yju2 |
C |
T |
17: 56,271,543 (GRCm39) |
Q155* |
probably null |
Het |
| Zfp275 |
A |
G |
X: 72,396,841 (GRCm39) |
T118A |
possibly damaging |
Het |
|
| Other mutations in Tdrd6 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00571:Tdrd6
|
APN |
17 |
43,939,051 (GRCm39) |
missense |
probably damaging |
0.96 |
|
IGL00844:Tdrd6
|
APN |
17 |
43,928,087 (GRCm39) |
missense |
probably benign |
|
|
IGL00845:Tdrd6
|
APN |
17 |
43,937,607 (GRCm39) |
missense |
probably benign |
0.06 |
|
IGL01558:Tdrd6
|
APN |
17 |
43,936,659 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01558:Tdrd6
|
APN |
17 |
43,935,657 (GRCm39) |
missense |
probably benign |
0.02 |
|
IGL01575:Tdrd6
|
APN |
17 |
43,938,871 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL01812:Tdrd6
|
APN |
17 |
43,936,065 (GRCm39) |
missense |
probably benign |
0.10 |
|
IGL02013:Tdrd6
|
APN |
17 |
43,936,837 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL02067:Tdrd6
|
APN |
17 |
43,939,100 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02112:Tdrd6
|
APN |
17 |
43,940,242 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02159:Tdrd6
|
APN |
17 |
43,939,281 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02226:Tdrd6
|
APN |
17 |
43,938,093 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02416:Tdrd6
|
APN |
17 |
43,935,629 (GRCm39) |
missense |
probably benign |
0.39 |
|
IGL02577:Tdrd6
|
APN |
17 |
43,937,728 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL02631:Tdrd6
|
APN |
17 |
43,937,110 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02738:Tdrd6
|
APN |
17 |
43,931,337 (GRCm39) |
missense |
probably benign |
0.06 |
|
IGL02792:Tdrd6
|
APN |
17 |
43,935,918 (GRCm39) |
missense |
probably benign |
|
|
IGL02929:Tdrd6
|
APN |
17 |
43,940,604 (GRCm39) |
missense |
possibly damaging |
0.61 |
|
IGL02934:Tdrd6
|
APN |
17 |
43,938,778 (GRCm39) |
missense |
probably benign |
0.42 |
|
IGL02954:Tdrd6
|
APN |
17 |
43,938,153 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
IGL02969:Tdrd6
|
APN |
17 |
43,938,440 (GRCm39) |
missense |
probably damaging |
0.98 |
|
IGL03006:Tdrd6
|
APN |
17 |
43,936,323 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03155:Tdrd6
|
APN |
17 |
43,936,398 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03219:Tdrd6
|
APN |
17 |
43,938,855 (GRCm39) |
missense |
probably benign |
0.04 |
|
IGL03372:Tdrd6
|
APN |
17 |
43,936,459 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Edward
|
UTSW |
17 |
43,938,106 (GRCm39) |
missense |
probably damaging |
1.00 |
|
eliza
|
UTSW |
17 |
43,939,053 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
Elizabeth
|
UTSW |
17 |
43,935,095 (GRCm39) |
missense |
probably benign |
0.00 |
|
henry
|
UTSW |
17 |
43,939,050 (GRCm39) |
missense |
probably damaging |
0.99 |
|
BB001:Tdrd6
|
UTSW |
17 |
43,938,697 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
BB011:Tdrd6
|
UTSW |
17 |
43,938,697 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
G1citation:Tdrd6
|
UTSW |
17 |
43,938,106 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0030:Tdrd6
|
UTSW |
17 |
43,937,482 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
R0057:Tdrd6
|
UTSW |
17 |
43,928,052 (GRCm39) |
splice site |
probably benign |
|
|
R0090:Tdrd6
|
UTSW |
17 |
43,939,132 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0270:Tdrd6
|
UTSW |
17 |
43,935,199 (GRCm39) |
missense |
probably benign |
|
|
R0463:Tdrd6
|
UTSW |
17 |
43,936,452 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0594:Tdrd6
|
UTSW |
17 |
43,940,274 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0650:Tdrd6
|
UTSW |
17 |
43,939,050 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1226:Tdrd6
|
UTSW |
17 |
43,937,523 (GRCm39) |
missense |
possibly damaging |
0.63 |
|
R1309:Tdrd6
|
UTSW |
17 |
43,937,512 (GRCm39) |
missense |
probably benign |
|
|
R1483:Tdrd6
|
UTSW |
17 |
43,938,498 (GRCm39) |
missense |
probably benign |
0.31 |
|
R1561:Tdrd6
|
UTSW |
17 |
43,936,515 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R1574:Tdrd6
|
UTSW |
17 |
43,936,515 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R1647:Tdrd6
|
UTSW |
17 |
43,938,000 (GRCm39) |
missense |
possibly damaging |
0.49 |
|
R1648:Tdrd6
|
UTSW |
17 |
43,938,000 (GRCm39) |
missense |
possibly damaging |
0.49 |
|
R1723:Tdrd6
|
UTSW |
17 |
43,939,218 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R1786:Tdrd6
|
UTSW |
17 |
43,935,724 (GRCm39) |
missense |
probably benign |
0.01 |
|
R1819:Tdrd6
|
UTSW |
17 |
43,937,442 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1836:Tdrd6
|
UTSW |
17 |
43,936,480 (GRCm39) |
missense |
probably benign |
0.03 |
|
R1892:Tdrd6
|
UTSW |
17 |
43,935,696 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1911:Tdrd6
|
UTSW |
17 |
43,937,979 (GRCm39) |
missense |
probably benign |
0.21 |
|
R1936:Tdrd6
|
UTSW |
17 |
43,937,358 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R2005:Tdrd6
|
UTSW |
17 |
43,939,546 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2132:Tdrd6
|
UTSW |
17 |
43,935,724 (GRCm39) |
missense |
probably benign |
0.01 |
|
R2133:Tdrd6
|
UTSW |
17 |
43,935,724 (GRCm39) |
missense |
probably benign |
0.01 |
|
R3010:Tdrd6
|
UTSW |
17 |
43,938,933 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4225:Tdrd6
|
UTSW |
17 |
43,936,864 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4448:Tdrd6
|
UTSW |
17 |
43,940,626 (GRCm39) |
missense |
probably benign |
0.26 |
|
R4449:Tdrd6
|
UTSW |
17 |
43,940,626 (GRCm39) |
missense |
probably benign |
0.26 |
|
R4531:Tdrd6
|
UTSW |
17 |
43,939,645 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R4624:Tdrd6
|
UTSW |
17 |
43,936,881 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4665:Tdrd6
|
UTSW |
17 |
43,935,007 (GRCm39) |
missense |
probably benign |
|
|
R4676:Tdrd6
|
UTSW |
17 |
43,938,501 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R4785:Tdrd6
|
UTSW |
17 |
43,936,467 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4912:Tdrd6
|
UTSW |
17 |
43,935,218 (GRCm39) |
missense |
probably benign |
0.34 |
|
R5134:Tdrd6
|
UTSW |
17 |
43,937,101 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5145:Tdrd6
|
UTSW |
17 |
43,936,966 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R5623:Tdrd6
|
UTSW |
17 |
43,940,224 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5712:Tdrd6
|
UTSW |
17 |
43,937,299 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5897:Tdrd6
|
UTSW |
17 |
43,935,768 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R5913:Tdrd6
|
UTSW |
17 |
43,939,302 (GRCm39) |
missense |
possibly damaging |
0.73 |
|
R6142:Tdrd6
|
UTSW |
17 |
43,940,373 (GRCm39) |
missense |
probably benign |
0.01 |
|
R6181:Tdrd6
|
UTSW |
17 |
43,939,788 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6195:Tdrd6
|
UTSW |
17 |
43,940,643 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6233:Tdrd6
|
UTSW |
17 |
43,940,643 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6289:Tdrd6
|
UTSW |
17 |
43,935,411 (GRCm39) |
missense |
probably benign |
0.01 |
|
R6315:Tdrd6
|
UTSW |
17 |
43,937,229 (GRCm39) |
missense |
probably benign |
0.02 |
|
R6578:Tdrd6
|
UTSW |
17 |
43,939,852 (GRCm39) |
missense |
possibly damaging |
0.65 |
|
R6645:Tdrd6
|
UTSW |
17 |
43,935,423 (GRCm39) |
missense |
probably benign |
0.10 |
|
R6822:Tdrd6
|
UTSW |
17 |
43,938,106 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7000:Tdrd6
|
UTSW |
17 |
43,938,599 (GRCm39) |
missense |
probably benign |
0.28 |
|
R7075:Tdrd6
|
UTSW |
17 |
43,936,065 (GRCm39) |
missense |
probably benign |
0.10 |
|
R7107:Tdrd6
|
UTSW |
17 |
43,935,095 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7381:Tdrd6
|
UTSW |
17 |
43,936,984 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7458:Tdrd6
|
UTSW |
17 |
43,935,937 (GRCm39) |
missense |
probably benign |
0.02 |
|
R7461:Tdrd6
|
UTSW |
17 |
43,938,817 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7505:Tdrd6
|
UTSW |
17 |
43,938,570 (GRCm39) |
missense |
not run |
|
|
R7583:Tdrd6
|
UTSW |
17 |
43,935,129 (GRCm39) |
missense |
probably benign |
0.29 |
|
R7613:Tdrd6
|
UTSW |
17 |
43,938,817 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7723:Tdrd6
|
UTSW |
17 |
43,936,851 (GRCm39) |
missense |
probably benign |
0.09 |
|
R7759:Tdrd6
|
UTSW |
17 |
43,935,730 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7924:Tdrd6
|
UTSW |
17 |
43,938,697 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R8002:Tdrd6
|
UTSW |
17 |
43,940,710 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R8134:Tdrd6
|
UTSW |
17 |
43,937,064 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8231:Tdrd6
|
UTSW |
17 |
43,933,026 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8242:Tdrd6
|
UTSW |
17 |
43,939,821 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8542:Tdrd6
|
UTSW |
17 |
43,935,783 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8713:Tdrd6
|
UTSW |
17 |
43,935,910 (GRCm39) |
missense |
probably benign |
0.28 |
|
R9100:Tdrd6
|
UTSW |
17 |
43,936,305 (GRCm39) |
missense |
possibly damaging |
0.76 |
|
R9201:Tdrd6
|
UTSW |
17 |
43,936,561 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9222:Tdrd6
|
UTSW |
17 |
43,939,231 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9369:Tdrd6
|
UTSW |
17 |
43,936,217 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9373:Tdrd6
|
UTSW |
17 |
43,939,053 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R9384:Tdrd6
|
UTSW |
17 |
43,937,783 (GRCm39) |
missense |
probably benign |
0.26 |
|
R9448:Tdrd6
|
UTSW |
17 |
43,936,567 (GRCm39) |
missense |
probably benign |
|
|
R9534:Tdrd6
|
UTSW |
17 |
43,936,510 (GRCm39) |
missense |
probably benign |
0.19 |
|
R9613:Tdrd6
|
UTSW |
17 |
43,939,518 (GRCm39) |
missense |
probably damaging |
0.99 |
|
X0065:Tdrd6
|
UTSW |
17 |
43,936,884 (GRCm39) |
missense |
probably damaging |
0.99 |
|
X0065:Tdrd6
|
UTSW |
17 |
43,936,044 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
Z1088:Tdrd6
|
UTSW |
17 |
43,937,409 (GRCm39) |
missense |
probably benign |
0.23 |
|
Z1177:Tdrd6
|
UTSW |
17 |
43,938,078 (GRCm39) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- TTGCTGTCTAATCGGGTGAC -3'
(R):5'- TACAATCCTGTTGCCTGGC -3'
Sequencing Primer
(F):5'- GCTCGGTAATAGCCATTTTCTTTC -3'
(R):5'- CTGACTGGTTTCTTCAGAGCCAG -3'
|
| Posted On |
2014-08-25 |
Incidental Mutation