Incidental Mutation 'R1996:Plxnb2'
| ID |
225781 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Plxnb2
|
| Ensembl Gene |
ENSMUSG00000036606 |
| Gene Name |
plexin B2 |
| Synonyms |
1110007H23Rik, Debt |
| MMRRC Submission |
040006-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably essential
(E-score: 0.943)
|
| Stock # |
R1996 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
|
| Chromosome |
15 |
| Chromosomal Location |
89039752-89064960 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
C to T
at 89042971 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Valine to Isoleucine
at position 1473
(V1473I)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000104955
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000060808]
[ENSMUST00000109331]
|
| AlphaFold |
B2RXS4 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000060808
AA Change: V1473I
PolyPhen 2
Score 0.066 (Sensitivity: 0.94; Specificity: 0.84)
|
| SMART Domains |
Protein: ENSMUSP00000051731
Gene: ENSMUSG00000036606
AA Change: V1473I
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
19 |
N/A |
INTRINSIC |
|
Sema
|
34 |
452 |
8.87e-92 |
SMART |
|
PSI
|
470 |
521 |
1.94e-10 |
SMART |
|
PSI
|
616 |
669 |
4.09e-1 |
SMART |
|
PSI
|
761 |
804 |
7.02e-8 |
SMART |
|
IPT
|
805 |
896 |
8.14e-19 |
SMART |
|
IPT
|
897 |
983 |
1.1e-15 |
SMART |
|
IPT
|
985 |
1096 |
5.06e-6 |
SMART |
|
Pfam:Plexin_cytopl
|
1275 |
1809 |
1.6e-225 |
PFAM |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000109331
AA Change: V1473I
PolyPhen 2
Score 0.130 (Sensitivity: 0.93; Specificity: 0.86)
|
| SMART Domains |
Protein: ENSMUSP00000104955
Gene: ENSMUSG00000036606
AA Change: V1473I
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
19 |
N/A |
INTRINSIC |
|
Sema
|
34 |
452 |
8.87e-92 |
SMART |
|
PSI
|
470 |
521 |
1.94e-10 |
SMART |
|
PSI
|
616 |
669 |
4.09e-1 |
SMART |
|
PSI
|
761 |
804 |
7.02e-8 |
SMART |
|
IPT
|
805 |
896 |
8.14e-19 |
SMART |
|
IPT
|
897 |
983 |
1.1e-15 |
SMART |
|
IPT
|
985 |
1096 |
5.06e-6 |
SMART |
|
Pfam:Plexin_cytopl
|
1274 |
1809 |
4.4e-251 |
PFAM |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000139372
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000143014
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000151418
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000197760
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000229966
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000230393
|
| Meta Mutation Damage Score |
0.0898 |
| Coding Region Coverage |
- 1x: 99.2%
- 3x: 98.6%
- 10x: 97.2%
- 20x: 95.0%
|
| Validation Efficiency |
99% (84/85) |
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] Members of the B class of plexins, such as PLXNB2 are transmembrane receptors that participate in axon guidance and cell migration in response to semaphorins (Perrot et al. (2002) [PubMed 12183458]).[supplied by OMIM, Mar 2008]
PHENOTYPE: Homozygotes for a targeted mutation of this gene die perinatally of exencephaly or survive and seem normal despite severe abnormalities in cerebellar layering and foliation; the external granule cell layer is disorganized due to continued proliferation and migration of differentiated granule cells. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 81 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| A2m |
T |
A |
6: 121,646,556 (GRCm39) |
W1069R |
probably damaging |
Het |
| Aaas |
C |
T |
15: 102,248,494 (GRCm39) |
V241I |
probably benign |
Het |
| Abca3 |
A |
G |
17: 24,606,506 (GRCm39) |
E787G |
probably damaging |
Het |
| Abi3bp |
A |
T |
16: 56,491,720 (GRCm39) |
E582D |
possibly damaging |
Het |
| Adam21 |
A |
G |
12: 81,606,376 (GRCm39) |
M462T |
possibly damaging |
Het |
| Alox12e |
T |
C |
11: 70,207,034 (GRCm39) |
T591A |
probably benign |
Het |
| Ankmy2 |
T |
C |
12: 36,243,796 (GRCm39) |
M337T |
probably benign |
Het |
| Antxrl |
A |
G |
14: 33,797,786 (GRCm39) |
N587S |
probably benign |
Het |
| Apol6 |
T |
A |
15: 76,934,956 (GRCm39) |
I75N |
probably benign |
Het |
| Atad2b |
A |
T |
12: 5,040,883 (GRCm39) |
H184L |
probably benign |
Het |
| Atf6b |
A |
T |
17: 34,871,961 (GRCm39) |
|
probably null |
Het |
| B3gnt4 |
G |
A |
5: 123,649,402 (GRCm39) |
V256I |
probably damaging |
Het |
| BC034090 |
C |
T |
1: 155,097,340 (GRCm39) |
|
probably benign |
Het |
| Bend4 |
C |
A |
5: 67,557,527 (GRCm39) |
V430F |
probably damaging |
Het |
| Camkv |
A |
G |
9: 107,824,320 (GRCm39) |
D244G |
probably damaging |
Het |
| Caps2 |
T |
A |
10: 112,039,908 (GRCm39) |
L450Q |
probably damaging |
Het |
| Ccr1 |
T |
A |
9: 123,763,551 (GRCm39) |
K326N |
probably benign |
Het |
| Cep135 |
T |
C |
5: 76,780,113 (GRCm39) |
I815T |
probably benign |
Het |
| Chchd4 |
A |
G |
6: 91,442,116 (GRCm39) |
Y101H |
probably damaging |
Het |
| Copb1 |
G |
C |
7: 113,831,438 (GRCm39) |
A570G |
probably benign |
Het |
| Cpsf2 |
C |
A |
12: 101,964,867 (GRCm39) |
T505K |
probably benign |
Het |
| Cwf19l2 |
A |
G |
9: 3,417,947 (GRCm39) |
R136G |
probably benign |
Het |
| Daxx |
A |
G |
17: 34,132,585 (GRCm39) |
T572A |
possibly damaging |
Het |
| Etaa1 |
C |
A |
11: 17,902,671 (GRCm39) |
D89Y |
probably damaging |
Het |
| Ezhip |
GTCATCATCATCATC |
GTCATCATCATCATCATC |
X: 5,994,645 (GRCm39) |
|
probably benign |
Het |
| Fchsd2 |
T |
C |
7: 100,927,660 (GRCm39) |
F701L |
probably benign |
Het |
| Fstl5 |
A |
T |
3: 76,615,141 (GRCm39) |
H734L |
probably benign |
Het |
| Gabbr1 |
T |
A |
17: 37,380,112 (GRCm39) |
W584R |
probably damaging |
Het |
| Galc |
T |
C |
12: 98,218,285 (GRCm39) |
D189G |
probably damaging |
Het |
| Gm9979 |
T |
C |
13: 40,859,228 (GRCm39) |
|
noncoding transcript |
Het |
| Grin2b |
T |
C |
6: 136,021,209 (GRCm39) |
S31G |
possibly damaging |
Het |
| Gtf2ird1 |
T |
C |
5: 134,405,740 (GRCm39) |
|
probably benign |
Het |
| Hoxc4 |
T |
C |
15: 102,944,183 (GRCm39) |
I187T |
probably damaging |
Het |
| Hsd3b6 |
A |
T |
3: 98,713,597 (GRCm39) |
I234N |
probably damaging |
Het |
| Ifit3b |
T |
C |
19: 34,588,877 (GRCm39) |
C18R |
probably damaging |
Het |
| Igdcc4 |
T |
A |
9: 65,029,101 (GRCm39) |
V246E |
probably damaging |
Het |
| Il1rap |
A |
T |
16: 26,541,243 (GRCm39) |
T495S |
probably benign |
Het |
| Kctd19 |
T |
C |
8: 106,121,932 (GRCm39) |
E205G |
probably null |
Het |
| Kif21a |
A |
T |
15: 90,878,574 (GRCm39) |
C235* |
probably null |
Het |
| Krt16 |
A |
T |
11: 100,139,614 (GRCm39) |
S35T |
unknown |
Het |
| Lamc2 |
T |
C |
1: 153,030,216 (GRCm39) |
D142G |
possibly damaging |
Het |
| Larp4 |
G |
T |
15: 99,882,844 (GRCm39) |
W22L |
probably damaging |
Het |
| Ldlrad1 |
C |
T |
4: 107,072,158 (GRCm39) |
R127* |
probably null |
Het |
| Mamdc2 |
G |
A |
19: 23,341,289 (GRCm39) |
Q229* |
probably null |
Het |
| Mbtd1 |
CT |
CTT |
11: 93,823,222 (GRCm39) |
|
probably null |
Het |
| Msln |
T |
A |
17: 25,973,193 (GRCm39) |
M1L |
possibly damaging |
Het |
| Mtch2 |
T |
C |
2: 90,677,665 (GRCm39) |
V8A |
possibly damaging |
Het |
| Nav3 |
A |
T |
10: 109,689,262 (GRCm39) |
N338K |
probably damaging |
Het |
| Or10x4 |
T |
C |
1: 174,218,983 (GRCm39) |
M116T |
probably damaging |
Het |
| Or51a39 |
A |
G |
7: 102,362,999 (GRCm39) |
L207P |
probably damaging |
Het |
| Or6c5 |
C |
A |
10: 129,074,298 (GRCm39) |
N93K |
possibly damaging |
Het |
| Otof |
A |
G |
5: 30,578,381 (GRCm39) |
V89A |
probably benign |
Het |
| Phka2 |
T |
C |
X: 159,324,411 (GRCm39) |
I255T |
probably benign |
Het |
| Pias2 |
T |
C |
18: 77,216,759 (GRCm39) |
|
probably null |
Het |
| Pja2 |
T |
A |
17: 64,594,639 (GRCm39) |
|
probably null |
Het |
| Pnpt1 |
T |
A |
11: 29,091,679 (GRCm39) |
D363E |
probably benign |
Het |
| Prdm5 |
A |
G |
6: 65,913,072 (GRCm39) |
Y207C |
probably damaging |
Het |
| Rexo5 |
T |
A |
7: 119,423,080 (GRCm39) |
V304E |
probably damaging |
Het |
| Robo1 |
G |
T |
16: 72,767,067 (GRCm39) |
R413L |
probably benign |
Het |
| Rsf1 |
G |
A |
7: 97,313,839 (GRCm39) |
E864K |
probably damaging |
Het |
| Scap |
C |
T |
9: 110,202,039 (GRCm39) |
|
probably benign |
Het |
| Scn8a |
T |
A |
15: 100,922,260 (GRCm39) |
M1311K |
probably damaging |
Het |
| Slc28a2 |
A |
T |
2: 122,286,043 (GRCm39) |
I460F |
probably damaging |
Het |
| Smco1 |
A |
G |
16: 32,092,730 (GRCm39) |
R134G |
probably benign |
Het |
| Spopfm1 |
A |
T |
3: 94,173,018 (GRCm39) |
M9L |
probably benign |
Het |
| Sspo |
A |
G |
6: 48,452,424 (GRCm39) |
E2651G |
possibly damaging |
Het |
| Stab2 |
T |
C |
10: 86,838,895 (GRCm39) |
N57S |
probably damaging |
Het |
| Tenm3 |
C |
A |
8: 48,681,703 (GRCm39) |
Q2642H |
probably damaging |
Het |
| Thsd7b |
G |
T |
1: 129,686,188 (GRCm39) |
E577* |
probably null |
Het |
| Tlr3 |
A |
G |
8: 45,850,734 (GRCm39) |
V721A |
probably benign |
Het |
| Tnik |
A |
G |
3: 28,719,829 (GRCm39) |
I1226V |
probably damaging |
Het |
| Traf3 |
A |
G |
12: 111,227,095 (GRCm39) |
K328E |
probably benign |
Het |
| Tyw1 |
T |
A |
5: 130,291,652 (GRCm39) |
|
probably benign |
Het |
| Vmn1r213 |
T |
G |
13: 23,196,473 (GRCm39) |
V352G |
probably benign |
Het |
| Vmn2r111 |
T |
C |
17: 22,767,062 (GRCm39) |
I812V |
probably benign |
Het |
| Vmn2r26 |
A |
G |
6: 124,038,144 (GRCm39) |
N573S |
probably damaging |
Het |
| Vmn2r45 |
G |
A |
7: 8,475,024 (GRCm39) |
T668I |
probably damaging |
Het |
| Zbtb20 |
T |
A |
16: 43,430,443 (GRCm39) |
V318E |
probably damaging |
Het |
| Zc2hc1c |
A |
G |
12: 85,343,434 (GRCm39) |
R524G |
probably benign |
Het |
| Zc3h18 |
C |
G |
8: 123,134,126 (GRCm39) |
|
probably benign |
Het |
| Zfp618 |
T |
C |
4: 63,049,452 (GRCm39) |
|
probably null |
Het |
|
| Other mutations in Plxnb2 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00546:Plxnb2
|
APN |
15 |
89,046,569 (GRCm39) |
splice site |
probably benign |
|
|
IGL01574:Plxnb2
|
APN |
15 |
89,046,886 (GRCm39) |
splice site |
probably null |
|
|
IGL01695:Plxnb2
|
APN |
15 |
89,041,417 (GRCm39) |
missense |
possibly damaging |
0.96 |
|
IGL01763:Plxnb2
|
APN |
15 |
89,046,184 (GRCm39) |
splice site |
probably null |
|
|
IGL01921:Plxnb2
|
APN |
15 |
89,048,474 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
IGL02129:Plxnb2
|
APN |
15 |
89,044,613 (GRCm39) |
missense |
probably benign |
0.04 |
|
IGL02153:Plxnb2
|
APN |
15 |
89,050,016 (GRCm39) |
nonsense |
probably null |
|
|
IGL02637:Plxnb2
|
APN |
15 |
89,048,260 (GRCm39) |
missense |
possibly damaging |
0.53 |
|
IGL02892:Plxnb2
|
APN |
15 |
89,045,425 (GRCm39) |
critical splice donor site |
probably null |
|
|
IGL03108:Plxnb2
|
APN |
15 |
89,042,234 (GRCm39) |
missense |
probably benign |
0.32 |
|
IGL03115:Plxnb2
|
APN |
15 |
89,046,641 (GRCm39) |
splice site |
probably benign |
|
|
P0040:Plxnb2
|
UTSW |
15 |
89,047,138 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0022:Plxnb2
|
UTSW |
15 |
89,047,479 (GRCm39) |
critical splice donor site |
probably null |
|
|
R0095:Plxnb2
|
UTSW |
15 |
89,049,534 (GRCm39) |
missense |
probably benign |
|
|
R0103:Plxnb2
|
UTSW |
15 |
89,045,972 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R0544:Plxnb2
|
UTSW |
15 |
89,042,816 (GRCm39) |
splice site |
probably benign |
|
|
R0671:Plxnb2
|
UTSW |
15 |
89,042,184 (GRCm39) |
missense |
probably benign |
0.14 |
|
R1279:Plxnb2
|
UTSW |
15 |
89,046,524 (GRCm39) |
missense |
probably benign |
0.02 |
|
R1530:Plxnb2
|
UTSW |
15 |
89,051,395 (GRCm39) |
missense |
probably benign |
|
|
R1542:Plxnb2
|
UTSW |
15 |
89,050,124 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1610:Plxnb2
|
UTSW |
15 |
89,042,696 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1686:Plxnb2
|
UTSW |
15 |
89,046,665 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1702:Plxnb2
|
UTSW |
15 |
89,046,187 (GRCm39) |
critical splice donor site |
probably null |
|
|
R1997:Plxnb2
|
UTSW |
15 |
89,042,971 (GRCm39) |
missense |
probably benign |
0.13 |
|
R2031:Plxnb2
|
UTSW |
15 |
89,047,013 (GRCm39) |
nonsense |
probably null |
|
|
R2049:Plxnb2
|
UTSW |
15 |
89,043,205 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2072:Plxnb2
|
UTSW |
15 |
89,042,654 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2076:Plxnb2
|
UTSW |
15 |
89,042,229 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2140:Plxnb2
|
UTSW |
15 |
89,040,765 (GRCm39) |
missense |
probably benign |
0.04 |
|
R2418:Plxnb2
|
UTSW |
15 |
89,045,272 (GRCm39) |
missense |
possibly damaging |
0.72 |
|
R2419:Plxnb2
|
UTSW |
15 |
89,045,272 (GRCm39) |
missense |
possibly damaging |
0.72 |
|
R3752:Plxnb2
|
UTSW |
15 |
89,041,458 (GRCm39) |
splice site |
probably benign |
|
|
R3825:Plxnb2
|
UTSW |
15 |
89,050,602 (GRCm39) |
missense |
probably benign |
0.05 |
|
R4154:Plxnb2
|
UTSW |
15 |
89,043,845 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R4197:Plxnb2
|
UTSW |
15 |
89,041,221 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4385:Plxnb2
|
UTSW |
15 |
89,044,826 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R4434:Plxnb2
|
UTSW |
15 |
89,047,006 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4678:Plxnb2
|
UTSW |
15 |
89,045,131 (GRCm39) |
missense |
probably benign |
0.37 |
|
R4717:Plxnb2
|
UTSW |
15 |
89,041,622 (GRCm39) |
nonsense |
probably null |
|
|
R4773:Plxnb2
|
UTSW |
15 |
89,051,150 (GRCm39) |
missense |
probably benign |
0.06 |
|
R4905:Plxnb2
|
UTSW |
15 |
89,041,614 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5368:Plxnb2
|
UTSW |
15 |
89,043,796 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R5418:Plxnb2
|
UTSW |
15 |
89,050,694 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5484:Plxnb2
|
UTSW |
15 |
89,048,412 (GRCm39) |
splice site |
probably null |
|
|
R5520:Plxnb2
|
UTSW |
15 |
89,051,746 (GRCm39) |
missense |
possibly damaging |
0.65 |
|
R5566:Plxnb2
|
UTSW |
15 |
89,048,223 (GRCm39) |
missense |
probably benign |
0.05 |
|
R5568:Plxnb2
|
UTSW |
15 |
89,041,638 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5619:Plxnb2
|
UTSW |
15 |
89,047,012 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R5685:Plxnb2
|
UTSW |
15 |
89,051,235 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5688:Plxnb2
|
UTSW |
15 |
89,042,899 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5809:Plxnb2
|
UTSW |
15 |
89,051,774 (GRCm39) |
missense |
possibly damaging |
0.61 |
|
R5813:Plxnb2
|
UTSW |
15 |
89,044,962 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
R5866:Plxnb2
|
UTSW |
15 |
89,051,775 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6016:Plxnb2
|
UTSW |
15 |
89,045,225 (GRCm39) |
missense |
possibly damaging |
0.55 |
|
R6117:Plxnb2
|
UTSW |
15 |
89,042,203 (GRCm39) |
missense |
probably benign |
0.04 |
|
R6187:Plxnb2
|
UTSW |
15 |
89,051,461 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6260:Plxnb2
|
UTSW |
15 |
89,049,494 (GRCm39) |
missense |
probably benign |
0.22 |
|
R6263:Plxnb2
|
UTSW |
15 |
89,046,189 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6269:Plxnb2
|
UTSW |
15 |
89,044,916 (GRCm39) |
missense |
probably benign |
0.18 |
|
R6351:Plxnb2
|
UTSW |
15 |
89,041,973 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R6522:Plxnb2
|
UTSW |
15 |
89,048,629 (GRCm39) |
missense |
probably benign |
0.18 |
|
R6856:Plxnb2
|
UTSW |
15 |
89,048,523 (GRCm39) |
missense |
probably benign |
0.27 |
|
R6930:Plxnb2
|
UTSW |
15 |
89,044,592 (GRCm39) |
missense |
probably benign |
|
|
R7354:Plxnb2
|
UTSW |
15 |
89,049,928 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R7513:Plxnb2
|
UTSW |
15 |
89,042,525 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R7522:Plxnb2
|
UTSW |
15 |
89,045,977 (GRCm39) |
missense |
probably benign |
0.20 |
|
R7730:Plxnb2
|
UTSW |
15 |
89,046,533 (GRCm39) |
missense |
probably benign |
|
|
R7766:Plxnb2
|
UTSW |
15 |
89,045,474 (GRCm39) |
missense |
probably benign |
0.01 |
|
R7781:Plxnb2
|
UTSW |
15 |
89,041,225 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R8126:Plxnb2
|
UTSW |
15 |
89,047,506 (GRCm39) |
missense |
probably benign |
|
|
R8131:Plxnb2
|
UTSW |
15 |
89,042,916 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8372:Plxnb2
|
UTSW |
15 |
89,042,696 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8736:Plxnb2
|
UTSW |
15 |
89,046,261 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8772:Plxnb2
|
UTSW |
15 |
89,046,949 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9022:Plxnb2
|
UTSW |
15 |
89,048,471 (GRCm39) |
missense |
possibly damaging |
0.59 |
|
R9044:Plxnb2
|
UTSW |
15 |
89,044,566 (GRCm39) |
splice site |
probably benign |
|
|
R9253:Plxnb2
|
UTSW |
15 |
89,052,015 (GRCm39) |
missense |
probably benign |
|
|
R9398:Plxnb2
|
UTSW |
15 |
89,045,122 (GRCm39) |
missense |
probably benign |
0.02 |
|
R9562:Plxnb2
|
UTSW |
15 |
89,050,136 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9568:Plxnb2
|
UTSW |
15 |
89,045,160 (GRCm39) |
nonsense |
probably null |
|
|
R9613:Plxnb2
|
UTSW |
15 |
89,048,496 (GRCm39) |
missense |
probably benign |
0.01 |
|
X0027:Plxnb2
|
UTSW |
15 |
89,044,916 (GRCm39) |
missense |
probably benign |
0.18 |
|
Z1177:Plxnb2
|
UTSW |
15 |
89,043,299 (GRCm39) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- ATGCTCTGCTCATTCCCAGG -3'
(R):5'- GAGTATGCGCCTCTGGTAAG -3'
Sequencing Primer
(F):5'- TCTGCTCATTCCCAGGCAGAG -3'
(R):5'- TGGTAAGTCCCCCAGAGC -3'
|
| Posted On |
2014-08-25 |
Incidental Mutation