Incidental Mutation 'R1996:Abi3bp'
| ID |
225790 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Abi3bp
|
| Ensembl Gene |
ENSMUSG00000035258 |
| Gene Name |
ABI family member 3 binding protein |
| Synonyms |
D930038M13Rik, TARSH, 5033411B22Rik, eratin |
| MMRRC Submission |
040006-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.090)
|
| Stock # |
R1996 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
|
| Chromosome |
16 |
| Chromosomal Location |
56298241-56510498 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to T
at 56491720 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Glutamic Acid to Aspartic acid
at position 582
(E582D)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000156155
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000048471]
[ENSMUST00000096012]
[ENSMUST00000096013]
[ENSMUST00000171000]
[ENSMUST00000231781]
[ENSMUST00000231832]
[ENSMUST00000231870]
|
| AlphaFold |
A0A338P6S8 |
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000048471
AA Change: E877D
PolyPhen 2
Score 0.463 (Sensitivity: 0.89; Specificity: 0.90)
|
| SMART Domains |
Protein: ENSMUSP00000036257
Gene: ENSMUSG00000035258
AA Change: E877D
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
21 |
N/A |
INTRINSIC |
|
FN3
|
114 |
203 |
3.08e-2 |
SMART |
|
low complexity region
|
433 |
446 |
N/A |
INTRINSIC |
|
low complexity region
|
516 |
528 |
N/A |
INTRINSIC |
|
low complexity region
|
579 |
591 |
N/A |
INTRINSIC |
|
low complexity region
|
734 |
747 |
N/A |
INTRINSIC |
|
low complexity region
|
751 |
764 |
N/A |
INTRINSIC |
|
FN3
|
941 |
1024 |
6.29e-8 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000096012
AA Change: E777D
PolyPhen 2
Score 0.080 (Sensitivity: 0.93; Specificity: 0.85)
|
| SMART Domains |
Protein: ENSMUSP00000093711
Gene: ENSMUSG00000035258
AA Change: E777D
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
21 |
N/A |
INTRINSIC |
|
FN3
|
114 |
203 |
3.08e-2 |
SMART |
|
low complexity region
|
433 |
446 |
N/A |
INTRINSIC |
|
low complexity region
|
634 |
647 |
N/A |
INTRINSIC |
|
low complexity region
|
651 |
664 |
N/A |
INTRINSIC |
|
FN3
|
841 |
924 |
6.29e-8 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000096013
AA Change: E813D
PolyPhen 2
Score 0.176 (Sensitivity: 0.92; Specificity: 0.87)
|
| SMART Domains |
Protein: ENSMUSP00000093712
Gene: ENSMUSG00000035258
AA Change: E813D
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
21 |
N/A |
INTRINSIC |
|
FN3
|
114 |
203 |
3.08e-2 |
SMART |
|
low complexity region
|
433 |
446 |
N/A |
INTRINSIC |
|
low complexity region
|
670 |
683 |
N/A |
INTRINSIC |
|
low complexity region
|
687 |
700 |
N/A |
INTRINSIC |
|
FN3
|
877 |
960 |
6.29e-8 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000171000
AA Change: E607D
PolyPhen 2
Score 0.173 (Sensitivity: 0.92; Specificity: 0.87)
|
| SMART Domains |
Protein: ENSMUSP00000128818
Gene: ENSMUSG00000035258
AA Change: E607D
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
21 |
N/A |
INTRINSIC |
|
FN3
|
114 |
203 |
3.08e-2 |
SMART |
|
low complexity region
|
464 |
477 |
N/A |
INTRINSIC |
|
low complexity region
|
481 |
494 |
N/A |
INTRINSIC |
|
FN3
|
671 |
754 |
6.29e-8 |
SMART |
|
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000231781
AA Change: E1335D
PolyPhen 2
Score 0.544 (Sensitivity: 0.88; Specificity: 0.91)
|
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000231832
AA Change: E582D
PolyPhen 2
Score 0.614 (Sensitivity: 0.87; Specificity: 0.91)
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000231870
AA Change: E797D
PolyPhen 2
Score 0.248 (Sensitivity: 0.91; Specificity: 0.88)
|
| Meta Mutation Damage Score |
0.1795 |
| Coding Region Coverage |
- 1x: 99.2%
- 3x: 98.6%
- 10x: 97.2%
- 20x: 95.0%
|
| Validation Efficiency |
99% (84/85) |
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 81 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| A2m |
T |
A |
6: 121,646,556 (GRCm39) |
W1069R |
probably damaging |
Het |
| Aaas |
C |
T |
15: 102,248,494 (GRCm39) |
V241I |
probably benign |
Het |
| Abca3 |
A |
G |
17: 24,606,506 (GRCm39) |
E787G |
probably damaging |
Het |
| Adam21 |
A |
G |
12: 81,606,376 (GRCm39) |
M462T |
possibly damaging |
Het |
| Alox12e |
T |
C |
11: 70,207,034 (GRCm39) |
T591A |
probably benign |
Het |
| Ankmy2 |
T |
C |
12: 36,243,796 (GRCm39) |
M337T |
probably benign |
Het |
| Antxrl |
A |
G |
14: 33,797,786 (GRCm39) |
N587S |
probably benign |
Het |
| Apol6 |
T |
A |
15: 76,934,956 (GRCm39) |
I75N |
probably benign |
Het |
| Atad2b |
A |
T |
12: 5,040,883 (GRCm39) |
H184L |
probably benign |
Het |
| Atf6b |
A |
T |
17: 34,871,961 (GRCm39) |
|
probably null |
Het |
| B3gnt4 |
G |
A |
5: 123,649,402 (GRCm39) |
V256I |
probably damaging |
Het |
| BC034090 |
C |
T |
1: 155,097,340 (GRCm39) |
|
probably benign |
Het |
| Bend4 |
C |
A |
5: 67,557,527 (GRCm39) |
V430F |
probably damaging |
Het |
| Camkv |
A |
G |
9: 107,824,320 (GRCm39) |
D244G |
probably damaging |
Het |
| Caps2 |
T |
A |
10: 112,039,908 (GRCm39) |
L450Q |
probably damaging |
Het |
| Ccr1 |
T |
A |
9: 123,763,551 (GRCm39) |
K326N |
probably benign |
Het |
| Cep135 |
T |
C |
5: 76,780,113 (GRCm39) |
I815T |
probably benign |
Het |
| Chchd4 |
A |
G |
6: 91,442,116 (GRCm39) |
Y101H |
probably damaging |
Het |
| Copb1 |
G |
C |
7: 113,831,438 (GRCm39) |
A570G |
probably benign |
Het |
| Cpsf2 |
C |
A |
12: 101,964,867 (GRCm39) |
T505K |
probably benign |
Het |
| Cwf19l2 |
A |
G |
9: 3,417,947 (GRCm39) |
R136G |
probably benign |
Het |
| Daxx |
A |
G |
17: 34,132,585 (GRCm39) |
T572A |
possibly damaging |
Het |
| Etaa1 |
C |
A |
11: 17,902,671 (GRCm39) |
D89Y |
probably damaging |
Het |
| Ezhip |
GTCATCATCATCATC |
GTCATCATCATCATCATC |
X: 5,994,645 (GRCm39) |
|
probably benign |
Het |
| Fchsd2 |
T |
C |
7: 100,927,660 (GRCm39) |
F701L |
probably benign |
Het |
| Fstl5 |
A |
T |
3: 76,615,141 (GRCm39) |
H734L |
probably benign |
Het |
| Gabbr1 |
T |
A |
17: 37,380,112 (GRCm39) |
W584R |
probably damaging |
Het |
| Galc |
T |
C |
12: 98,218,285 (GRCm39) |
D189G |
probably damaging |
Het |
| Gm9979 |
T |
C |
13: 40,859,228 (GRCm39) |
|
noncoding transcript |
Het |
| Grin2b |
T |
C |
6: 136,021,209 (GRCm39) |
S31G |
possibly damaging |
Het |
| Gtf2ird1 |
T |
C |
5: 134,405,740 (GRCm39) |
|
probably benign |
Het |
| Hoxc4 |
T |
C |
15: 102,944,183 (GRCm39) |
I187T |
probably damaging |
Het |
| Hsd3b6 |
A |
T |
3: 98,713,597 (GRCm39) |
I234N |
probably damaging |
Het |
| Ifit3b |
T |
C |
19: 34,588,877 (GRCm39) |
C18R |
probably damaging |
Het |
| Igdcc4 |
T |
A |
9: 65,029,101 (GRCm39) |
V246E |
probably damaging |
Het |
| Il1rap |
A |
T |
16: 26,541,243 (GRCm39) |
T495S |
probably benign |
Het |
| Kctd19 |
T |
C |
8: 106,121,932 (GRCm39) |
E205G |
probably null |
Het |
| Kif21a |
A |
T |
15: 90,878,574 (GRCm39) |
C235* |
probably null |
Het |
| Krt16 |
A |
T |
11: 100,139,614 (GRCm39) |
S35T |
unknown |
Het |
| Lamc2 |
T |
C |
1: 153,030,216 (GRCm39) |
D142G |
possibly damaging |
Het |
| Larp4 |
G |
T |
15: 99,882,844 (GRCm39) |
W22L |
probably damaging |
Het |
| Ldlrad1 |
C |
T |
4: 107,072,158 (GRCm39) |
R127* |
probably null |
Het |
| Mamdc2 |
G |
A |
19: 23,341,289 (GRCm39) |
Q229* |
probably null |
Het |
| Mbtd1 |
CT |
CTT |
11: 93,823,222 (GRCm39) |
|
probably null |
Het |
| Msln |
T |
A |
17: 25,973,193 (GRCm39) |
M1L |
possibly damaging |
Het |
| Mtch2 |
T |
C |
2: 90,677,665 (GRCm39) |
V8A |
possibly damaging |
Het |
| Nav3 |
A |
T |
10: 109,689,262 (GRCm39) |
N338K |
probably damaging |
Het |
| Or10x4 |
T |
C |
1: 174,218,983 (GRCm39) |
M116T |
probably damaging |
Het |
| Or51a39 |
A |
G |
7: 102,362,999 (GRCm39) |
L207P |
probably damaging |
Het |
| Or6c5 |
C |
A |
10: 129,074,298 (GRCm39) |
N93K |
possibly damaging |
Het |
| Otof |
A |
G |
5: 30,578,381 (GRCm39) |
V89A |
probably benign |
Het |
| Phka2 |
T |
C |
X: 159,324,411 (GRCm39) |
I255T |
probably benign |
Het |
| Pias2 |
T |
C |
18: 77,216,759 (GRCm39) |
|
probably null |
Het |
| Pja2 |
T |
A |
17: 64,594,639 (GRCm39) |
|
probably null |
Het |
| Plxnb2 |
C |
T |
15: 89,042,971 (GRCm39) |
V1473I |
probably benign |
Het |
| Pnpt1 |
T |
A |
11: 29,091,679 (GRCm39) |
D363E |
probably benign |
Het |
| Prdm5 |
A |
G |
6: 65,913,072 (GRCm39) |
Y207C |
probably damaging |
Het |
| Rexo5 |
T |
A |
7: 119,423,080 (GRCm39) |
V304E |
probably damaging |
Het |
| Robo1 |
G |
T |
16: 72,767,067 (GRCm39) |
R413L |
probably benign |
Het |
| Rsf1 |
G |
A |
7: 97,313,839 (GRCm39) |
E864K |
probably damaging |
Het |
| Scap |
C |
T |
9: 110,202,039 (GRCm39) |
|
probably benign |
Het |
| Scn8a |
T |
A |
15: 100,922,260 (GRCm39) |
M1311K |
probably damaging |
Het |
| Slc28a2 |
A |
T |
2: 122,286,043 (GRCm39) |
I460F |
probably damaging |
Het |
| Smco1 |
A |
G |
16: 32,092,730 (GRCm39) |
R134G |
probably benign |
Het |
| Spopfm1 |
A |
T |
3: 94,173,018 (GRCm39) |
M9L |
probably benign |
Het |
| Sspo |
A |
G |
6: 48,452,424 (GRCm39) |
E2651G |
possibly damaging |
Het |
| Stab2 |
T |
C |
10: 86,838,895 (GRCm39) |
N57S |
probably damaging |
Het |
| Tenm3 |
C |
A |
8: 48,681,703 (GRCm39) |
Q2642H |
probably damaging |
Het |
| Thsd7b |
G |
T |
1: 129,686,188 (GRCm39) |
E577* |
probably null |
Het |
| Tlr3 |
A |
G |
8: 45,850,734 (GRCm39) |
V721A |
probably benign |
Het |
| Tnik |
A |
G |
3: 28,719,829 (GRCm39) |
I1226V |
probably damaging |
Het |
| Traf3 |
A |
G |
12: 111,227,095 (GRCm39) |
K328E |
probably benign |
Het |
| Tyw1 |
T |
A |
5: 130,291,652 (GRCm39) |
|
probably benign |
Het |
| Vmn1r213 |
T |
G |
13: 23,196,473 (GRCm39) |
V352G |
probably benign |
Het |
| Vmn2r111 |
T |
C |
17: 22,767,062 (GRCm39) |
I812V |
probably benign |
Het |
| Vmn2r26 |
A |
G |
6: 124,038,144 (GRCm39) |
N573S |
probably damaging |
Het |
| Vmn2r45 |
G |
A |
7: 8,475,024 (GRCm39) |
T668I |
probably damaging |
Het |
| Zbtb20 |
T |
A |
16: 43,430,443 (GRCm39) |
V318E |
probably damaging |
Het |
| Zc2hc1c |
A |
G |
12: 85,343,434 (GRCm39) |
R524G |
probably benign |
Het |
| Zc3h18 |
C |
G |
8: 123,134,126 (GRCm39) |
|
probably benign |
Het |
| Zfp618 |
T |
C |
4: 63,049,452 (GRCm39) |
|
probably null |
Het |
|
| Other mutations in Abi3bp |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00780:Abi3bp
|
APN |
16 |
56,423,168 (GRCm39) |
missense |
probably null |
0.99 |
|
IGL01580:Abi3bp
|
APN |
16 |
56,495,573 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01633:Abi3bp
|
APN |
16 |
56,498,163 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01783:Abi3bp
|
APN |
16 |
56,353,332 (GRCm39) |
critical splice donor site |
probably null |
|
|
IGL01866:Abi3bp
|
APN |
16 |
56,492,336 (GRCm39) |
missense |
probably benign |
0.19 |
|
IGL02022:Abi3bp
|
APN |
16 |
56,412,999 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02086:Abi3bp
|
APN |
16 |
56,462,930 (GRCm39) |
splice site |
probably benign |
|
|
IGL02122:Abi3bp
|
APN |
16 |
56,507,491 (GRCm39) |
splice site |
probably benign |
|
|
IGL02155:Abi3bp
|
APN |
16 |
56,408,327 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL02351:Abi3bp
|
APN |
16 |
56,474,418 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
IGL02358:Abi3bp
|
APN |
16 |
56,474,418 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
IGL02418:Abi3bp
|
APN |
16 |
56,424,479 (GRCm39) |
splice site |
probably benign |
|
|
IGL02559:Abi3bp
|
APN |
16 |
56,507,433 (GRCm39) |
nonsense |
probably null |
|
|
IGL02617:Abi3bp
|
APN |
16 |
56,394,807 (GRCm39) |
nonsense |
probably null |
|
|
IGL02810:Abi3bp
|
APN |
16 |
56,498,138 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03057:Abi3bp
|
APN |
16 |
56,488,754 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
IGL03174:Abi3bp
|
APN |
16 |
56,435,110 (GRCm39) |
missense |
possibly damaging |
0.64 |
|
R0389:Abi3bp
|
UTSW |
16 |
56,491,670 (GRCm39) |
missense |
possibly damaging |
0.79 |
|
R0485:Abi3bp
|
UTSW |
16 |
56,424,375 (GRCm39) |
splice site |
probably null |
|
|
R0557:Abi3bp
|
UTSW |
16 |
56,488,750 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R0616:Abi3bp
|
UTSW |
16 |
56,474,433 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0685:Abi3bp
|
UTSW |
16 |
56,353,316 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R0783:Abi3bp
|
UTSW |
16 |
56,415,601 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R0828:Abi3bp
|
UTSW |
16 |
56,498,193 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0841:Abi3bp
|
UTSW |
16 |
56,488,639 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R1078:Abi3bp
|
UTSW |
16 |
56,474,444 (GRCm39) |
critical splice donor site |
probably null |
|
|
R1101:Abi3bp
|
UTSW |
16 |
56,426,521 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1116:Abi3bp
|
UTSW |
16 |
56,506,792 (GRCm39) |
splice site |
probably benign |
|
|
R1145:Abi3bp
|
UTSW |
16 |
56,488,639 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R1145:Abi3bp
|
UTSW |
16 |
56,488,639 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R1317:Abi3bp
|
UTSW |
16 |
56,488,672 (GRCm39) |
missense |
possibly damaging |
0.79 |
|
R1384:Abi3bp
|
UTSW |
16 |
56,394,862 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1460:Abi3bp
|
UTSW |
16 |
56,382,780 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1730:Abi3bp
|
UTSW |
16 |
56,488,642 (GRCm39) |
missense |
possibly damaging |
0.62 |
|
R1761:Abi3bp
|
UTSW |
16 |
56,488,672 (GRCm39) |
missense |
possibly damaging |
0.79 |
|
R1830:Abi3bp
|
UTSW |
16 |
56,408,348 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1873:Abi3bp
|
UTSW |
16 |
56,394,862 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1875:Abi3bp
|
UTSW |
16 |
56,394,862 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2018:Abi3bp
|
UTSW |
16 |
56,498,159 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2019:Abi3bp
|
UTSW |
16 |
56,498,159 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2035:Abi3bp
|
UTSW |
16 |
56,480,581 (GRCm39) |
missense |
probably benign |
0.21 |
|
R2118:Abi3bp
|
UTSW |
16 |
56,298,227 (GRCm39) |
unclassified |
probably benign |
|
|
R2202:Abi3bp
|
UTSW |
16 |
56,471,088 (GRCm39) |
nonsense |
probably null |
|
|
R2202:Abi3bp
|
UTSW |
16 |
56,433,566 (GRCm39) |
missense |
probably benign |
0.06 |
|
R2203:Abi3bp
|
UTSW |
16 |
56,433,566 (GRCm39) |
missense |
probably benign |
0.06 |
|
R3030:Abi3bp
|
UTSW |
16 |
56,477,682 (GRCm39) |
missense |
possibly damaging |
0.79 |
|
R3952:Abi3bp
|
UTSW |
16 |
56,424,401 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
R4176:Abi3bp
|
UTSW |
16 |
56,472,563 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R4296:Abi3bp
|
UTSW |
16 |
56,488,673 (GRCm39) |
missense |
probably benign |
0.05 |
|
R4301:Abi3bp
|
UTSW |
16 |
56,377,266 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4354:Abi3bp
|
UTSW |
16 |
56,353,314 (GRCm39) |
missense |
probably benign |
0.05 |
|
R4417:Abi3bp
|
UTSW |
16 |
56,474,398 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4716:Abi3bp
|
UTSW |
16 |
56,471,088 (GRCm39) |
nonsense |
probably null |
|
|
R4808:Abi3bp
|
UTSW |
16 |
56,414,879 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R4814:Abi3bp
|
UTSW |
16 |
56,471,116 (GRCm39) |
missense |
probably benign |
0.06 |
|
R5016:Abi3bp
|
UTSW |
16 |
56,491,631 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R5290:Abi3bp
|
UTSW |
16 |
56,462,838 (GRCm39) |
splice site |
probably null |
|
|
R5891:Abi3bp
|
UTSW |
16 |
56,426,496 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5897:Abi3bp
|
UTSW |
16 |
56,425,032 (GRCm39) |
missense |
possibly damaging |
0.53 |
|
R6146:Abi3bp
|
UTSW |
16 |
56,491,628 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6267:Abi3bp
|
UTSW |
16 |
56,414,860 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R6905:Abi3bp
|
UTSW |
16 |
56,394,880 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6908:Abi3bp
|
UTSW |
16 |
56,477,668 (GRCm39) |
missense |
probably benign |
0.01 |
|
R6917:Abi3bp
|
UTSW |
16 |
56,437,684 (GRCm39) |
splice site |
probably null |
|
|
R7071:Abi3bp
|
UTSW |
16 |
56,449,503 (GRCm39) |
nonsense |
probably null |
|
|
R7194:Abi3bp
|
UTSW |
16 |
56,382,734 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7476:Abi3bp
|
UTSW |
16 |
56,435,109 (GRCm39) |
nonsense |
probably null |
|
|
R7554:Abi3bp
|
UTSW |
16 |
56,438,575 (GRCm39) |
splice site |
probably null |
|
|
R7571:Abi3bp
|
UTSW |
16 |
56,451,345 (GRCm39) |
splice site |
probably null |
|
|
R7661:Abi3bp
|
UTSW |
16 |
56,453,263 (GRCm39) |
splice site |
probably null |
|
|
R7662:Abi3bp
|
UTSW |
16 |
56,437,686 (GRCm39) |
splice site |
probably null |
|
|
R7910:Abi3bp
|
UTSW |
16 |
56,498,105 (GRCm39) |
nonsense |
probably null |
|
|
R8121:Abi3bp
|
UTSW |
16 |
56,452,241 (GRCm39) |
missense |
unknown |
|
|
R8781:Abi3bp
|
UTSW |
16 |
56,426,512 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R8790:Abi3bp
|
UTSW |
16 |
56,495,437 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8828:Abi3bp
|
UTSW |
16 |
56,507,455 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9094:Abi3bp
|
UTSW |
16 |
56,456,590 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9135:Abi3bp
|
UTSW |
16 |
56,417,173 (GRCm39) |
missense |
probably benign |
0.21 |
|
R9282:Abi3bp
|
UTSW |
16 |
56,440,867 (GRCm39) |
missense |
unknown |
|
|
R9363:Abi3bp
|
UTSW |
16 |
56,438,575 (GRCm39) |
splice site |
probably null |
|
|
R9464:Abi3bp
|
UTSW |
16 |
56,409,046 (GRCm39) |
missense |
possibly damaging |
0.48 |
|
R9506:Abi3bp
|
UTSW |
16 |
56,437,773 (GRCm39) |
missense |
unknown |
|
|
RF008:Abi3bp
|
UTSW |
16 |
56,447,952 (GRCm39) |
intron |
probably benign |
|
|
RF016:Abi3bp
|
UTSW |
16 |
56,447,950 (GRCm39) |
frame shift |
probably null |
|
|
RF052:Abi3bp
|
UTSW |
16 |
56,447,948 (GRCm39) |
intron |
probably benign |
|
|
RF061:Abi3bp
|
UTSW |
16 |
56,447,950 (GRCm39) |
frame shift |
probably null |
|
|
| Predicted Primers |
PCR Primer
(F):5'- TCAAGAACCAGGTCTTGCGTG -3'
(R):5'- GCGTATTCTGTAACAAGAGGTTGAC -3'
Sequencing Primer
(F):5'- GATCATGCCAAGCCACATGGTG -3'
(R):5'- TCTGTAACAAGAGGTTGACAATAATG -3'
|
| Posted On |
2014-08-25 |
Incidental Mutation