Incidental Mutation 'R2001:Sphkap'
| ID |
225878 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Sphkap
|
| Ensembl Gene |
ENSMUSG00000026163 |
| Gene Name |
SPHK1 interactor, AKAP domain containing |
| Synonyms |
SKIP, A930009L15Rik, 4930544G21Rik |
| MMRRC Submission |
040011-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.074)
|
| Stock # |
R2001 (G1)
|
| Quality Score |
225 |
|
Status
|
Not validated
|
| Chromosome |
1 |
| Chromosomal Location |
83233163-83385853 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to T
at 83254383 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Methionine to Lysine
at position 835
(M835K)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000124384
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000159078]
[ENSMUST00000160953]
|
| AlphaFold |
no structure available at present |
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000053075
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000159078
AA Change: M835K
PolyPhen 2
Score 0.999 (Sensitivity: 0.14; Specificity: 0.99)
|
| SMART Domains |
Protein: ENSMUSP00000124384
Gene: ENSMUSG00000026163
AA Change: M835K
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
303 |
314 |
N/A |
INTRINSIC |
|
SCOP:d1ash__
|
382 |
462 |
5e-3 |
SMART |
|
low complexity region
|
809 |
819 |
N/A |
INTRINSIC |
|
low complexity region
|
854 |
865 |
N/A |
INTRINSIC |
|
low complexity region
|
1202 |
1221 |
N/A |
INTRINSIC |
|
low complexity region
|
1243 |
1254 |
N/A |
INTRINSIC |
|
Pfam:AKAP_110
|
1281 |
1398 |
7.5e-13 |
PFAM |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000160953
AA Change: M1122K
PolyPhen 2
Score 0.996 (Sensitivity: 0.55; Specificity: 0.98)
|
| SMART Domains |
Protein: ENSMUSP00000124872
Gene: ENSMUSG00000026163
AA Change: M1122K
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
590 |
601 |
N/A |
INTRINSIC |
|
SCOP:d1ash__
|
669 |
749 |
6e-3 |
SMART |
|
low complexity region
|
1096 |
1106 |
N/A |
INTRINSIC |
|
low complexity region
|
1141 |
1152 |
N/A |
INTRINSIC |
|
low complexity region
|
1489 |
1508 |
N/A |
INTRINSIC |
|
Pfam:AKAP_110
|
1540 |
1655 |
6.4e-12 |
PFAM |
|
| Coding Region Coverage |
- 1x: 99.2%
- 3x: 98.6%
- 10x: 97.1%
- 20x: 94.6%
|
| Validation Efficiency |
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 96 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 4932414N04Rik |
T |
C |
2: 68,571,800 (GRCm39) |
S559P |
probably benign |
Het |
| A430005L14Rik |
T |
A |
4: 154,044,314 (GRCm39) |
C42S |
probably damaging |
Het |
| Abca13 |
A |
T |
11: 9,223,967 (GRCm39) |
T449S |
probably benign |
Het |
| Acvr1c |
T |
A |
2: 58,205,987 (GRCm39) |
Q41L |
probably benign |
Het |
| Adamts13 |
C |
T |
2: 26,864,002 (GRCm39) |
P60L |
probably benign |
Het |
| Adamts20 |
T |
C |
15: 94,245,599 (GRCm39) |
T568A |
possibly damaging |
Het |
| Ago1 |
T |
C |
4: 126,348,187 (GRCm39) |
I44V |
probably null |
Het |
| Agtpbp1 |
TGAAGATGCATCTTGAGAAGA |
TGAAGA |
13: 59,623,617 (GRCm39) |
|
probably null |
Het |
| Ankrd28 |
A |
T |
14: 31,467,293 (GRCm39) |
V39E |
possibly damaging |
Het |
| Apaf1 |
A |
G |
10: 90,897,676 (GRCm39) |
V269A |
possibly damaging |
Het |
| Astn1 |
A |
G |
1: 158,348,091 (GRCm39) |
N506D |
probably damaging |
Het |
| BC051019 |
G |
A |
7: 109,319,758 (GRCm39) |
Q102* |
probably null |
Het |
| Bpifb5 |
A |
G |
2: 154,075,199 (GRCm39) |
T376A |
possibly damaging |
Het |
| Ccdc121rt1 |
G |
T |
1: 181,338,551 (GRCm39) |
Q134K |
probably benign |
Het |
| Ccl20 |
ATT |
ATTT |
1: 83,095,576 (GRCm39) |
|
probably null |
Het |
| Ccl6 |
G |
T |
11: 83,480,163 (GRCm39) |
P68T |
possibly damaging |
Het |
| Cd300ld |
A |
T |
11: 114,878,156 (GRCm39) |
F119I |
probably benign |
Het |
| Cdk2ap2 |
A |
G |
19: 4,147,903 (GRCm39) |
M57V |
possibly damaging |
Het |
| Cemip2 |
A |
G |
19: 21,779,351 (GRCm39) |
D387G |
probably benign |
Het |
| Chkb |
C |
T |
15: 89,312,969 (GRCm39) |
G36E |
probably damaging |
Het |
| Col11a1 |
A |
G |
3: 113,958,942 (GRCm39) |
|
probably null |
Het |
| Ctla2b |
T |
C |
13: 61,043,881 (GRCm39) |
Y120C |
probably damaging |
Het |
| Ctnnd1 |
T |
C |
2: 84,450,704 (GRCm39) |
N172S |
probably benign |
Het |
| Cyp2a22 |
G |
A |
7: 26,634,197 (GRCm39) |
P319L |
probably damaging |
Het |
| Dcaf12 |
A |
C |
4: 41,302,804 (GRCm39) |
V117G |
probably damaging |
Het |
| Ddx6 |
A |
G |
9: 44,518,831 (GRCm39) |
T48A |
probably benign |
Het |
| Dgki |
T |
C |
6: 36,842,736 (GRCm39) |
D923G |
possibly damaging |
Het |
| Dhx37 |
G |
T |
5: 125,504,528 (GRCm39) |
T345K |
probably damaging |
Het |
| Dhx9 |
A |
T |
1: 153,331,857 (GRCm39) |
Y1370* |
probably null |
Het |
| Dnah7b |
T |
C |
1: 46,181,247 (GRCm39) |
S1045P |
possibly damaging |
Het |
| Dnmbp |
G |
C |
19: 43,838,612 (GRCm39) |
T1071S |
possibly damaging |
Het |
| Dspp |
T |
A |
5: 104,326,425 (GRCm39) |
S929R |
unknown |
Het |
| Dst |
A |
T |
1: 34,223,144 (GRCm39) |
E1625D |
probably damaging |
Het |
| Egflam |
T |
A |
15: 7,272,048 (GRCm39) |
H630L |
probably benign |
Het |
| Elane |
T |
C |
10: 79,723,593 (GRCm39) |
V186A |
possibly damaging |
Het |
| Fam209 |
C |
A |
2: 172,314,689 (GRCm39) |
N59K |
probably benign |
Het |
| Gbe1 |
A |
G |
16: 70,325,814 (GRCm39) |
E617G |
probably damaging |
Het |
| Get3 |
T |
C |
8: 85,751,789 (GRCm39) |
S36G |
probably damaging |
Het |
| Gfra1 |
A |
G |
19: 58,288,707 (GRCm39) |
L246P |
probably damaging |
Het |
| Gria2 |
T |
C |
3: 80,618,112 (GRCm39) |
T308A |
probably benign |
Het |
| Grip2 |
A |
T |
6: 91,756,831 (GRCm39) |
V540D |
probably benign |
Het |
| Hhipl1 |
A |
T |
12: 108,288,118 (GRCm39) |
I575F |
possibly damaging |
Het |
| Hmcn1 |
T |
A |
1: 150,614,364 (GRCm39) |
E1347D |
possibly damaging |
Het |
| Itga2b |
C |
A |
11: 102,358,165 (GRCm39) |
A187S |
probably benign |
Het |
| Kalrn |
C |
A |
16: 33,848,415 (GRCm39) |
R469M |
probably damaging |
Het |
| Kif23 |
A |
T |
9: 61,834,666 (GRCm39) |
C426* |
probably null |
Het |
| Lck |
T |
C |
4: 129,442,730 (GRCm39) |
N475S |
probably benign |
Het |
| Leng8 |
A |
G |
7: 4,148,073 (GRCm39) |
N642S |
probably damaging |
Het |
| Lingo4 |
T |
A |
3: 94,310,382 (GRCm39) |
I440N |
probably damaging |
Het |
| Lrrc4 |
A |
G |
6: 28,830,904 (GRCm39) |
F237S |
probably damaging |
Het |
| Magel2 |
G |
A |
7: 62,028,844 (GRCm39) |
V583I |
unknown |
Het |
| Naip2 |
A |
T |
13: 100,281,096 (GRCm39) |
I1316N |
probably damaging |
Het |
| Naip6 |
C |
T |
13: 100,437,237 (GRCm39) |
G429S |
probably benign |
Het |
| Noct |
C |
T |
3: 51,155,465 (GRCm39) |
R78C |
probably damaging |
Het |
| Npbwr1 |
A |
G |
1: 5,987,394 (GRCm39) |
V40A |
possibly damaging |
Het |
| Nsd2 |
A |
G |
5: 34,000,746 (GRCm39) |
N88D |
probably damaging |
Het |
| Or1e29 |
T |
A |
11: 73,667,539 (GRCm39) |
I205F |
probably benign |
Het |
| Or5ap2 |
T |
A |
2: 85,680,744 (GRCm39) |
V316E |
probably benign |
Het |
| Or6c210 |
T |
A |
10: 129,496,290 (GRCm39) |
I205N |
probably benign |
Het |
| Or8k28 |
T |
C |
2: 86,285,817 (GRCm39) |
H266R |
probably benign |
Het |
| Pak5 |
T |
A |
2: 135,958,557 (GRCm39) |
H177L |
probably benign |
Het |
| Pard3 |
C |
T |
8: 127,791,097 (GRCm39) |
|
probably null |
Het |
| Pde4c |
A |
G |
8: 71,200,007 (GRCm39) |
|
probably null |
Het |
| Pde6h |
T |
A |
6: 136,940,203 (GRCm39) |
I63N |
probably damaging |
Het |
| Phldb2 |
T |
C |
16: 45,594,558 (GRCm39) |
K916E |
possibly damaging |
Het |
| Ppig |
T |
C |
2: 69,571,988 (GRCm39) |
S236P |
unknown |
Het |
| Ptprd |
T |
C |
4: 75,872,359 (GRCm39) |
Y1370C |
probably damaging |
Het |
| Pzp |
T |
C |
6: 128,493,083 (GRCm39) |
T352A |
probably benign |
Het |
| Rab3gap1 |
A |
G |
1: 127,831,456 (GRCm39) |
Y177C |
possibly damaging |
Het |
| Rasgef1a |
G |
A |
6: 118,066,157 (GRCm39) |
V457M |
probably benign |
Het |
| Scel |
A |
T |
14: 103,848,226 (GRCm39) |
T616S |
possibly damaging |
Het |
| Sel1l |
A |
T |
12: 91,793,324 (GRCm39) |
Y228* |
probably null |
Het |
| Sgms1 |
A |
G |
19: 32,137,083 (GRCm39) |
V161A |
possibly damaging |
Het |
| Slfnl1 |
T |
C |
4: 120,390,424 (GRCm39) |
L25P |
probably benign |
Het |
| Smad5 |
A |
G |
13: 56,885,187 (GRCm39) |
T432A |
probably damaging |
Het |
| Sohlh2 |
T |
C |
3: 55,099,762 (GRCm39) |
|
probably null |
Het |
| Sqor |
A |
C |
2: 122,640,018 (GRCm39) |
T174P |
probably damaging |
Het |
| Stkld1 |
T |
C |
2: 26,842,759 (GRCm39) |
V577A |
probably damaging |
Het |
| Sulf2 |
T |
A |
2: 165,922,773 (GRCm39) |
E652D |
probably benign |
Het |
| Sycp2 |
T |
A |
2: 178,019,848 (GRCm39) |
Q556L |
probably benign |
Het |
| Syk |
A |
G |
13: 52,765,274 (GRCm39) |
T134A |
probably benign |
Het |
| Tas2r122 |
T |
A |
6: 132,688,585 (GRCm39) |
I103F |
possibly damaging |
Het |
| Tex10 |
A |
G |
4: 48,451,940 (GRCm39) |
W729R |
probably damaging |
Het |
| Tex261 |
G |
T |
6: 83,750,713 (GRCm39) |
P95T |
probably damaging |
Het |
| Tm2d2 |
T |
C |
8: 25,507,523 (GRCm39) |
S47P |
probably benign |
Het |
| Tmem95 |
A |
G |
11: 69,767,817 (GRCm39) |
S128P |
probably damaging |
Het |
| Tnxb |
G |
A |
17: 34,911,553 (GRCm39) |
A1619T |
possibly damaging |
Het |
| Trappc9 |
A |
G |
15: 72,929,885 (GRCm39) |
I157T |
probably damaging |
Het |
| Unc13c |
T |
A |
9: 73,390,897 (GRCm39) |
|
probably null |
Het |
| Upb1 |
A |
T |
10: 75,265,803 (GRCm39) |
Y210F |
probably damaging |
Het |
| Urb1 |
T |
C |
16: 90,559,232 (GRCm39) |
M1684V |
probably benign |
Het |
| Wnk2 |
G |
A |
13: 49,232,158 (GRCm39) |
P727S |
possibly damaging |
Het |
| Zfp1004 |
T |
A |
2: 150,034,867 (GRCm39) |
M396K |
probably benign |
Het |
| Zfp551 |
A |
T |
7: 12,150,276 (GRCm39) |
S378T |
probably damaging |
Het |
| Zfp598 |
T |
C |
17: 24,888,898 (GRCm39) |
V56A |
possibly damaging |
Het |
| Zfp945 |
C |
T |
17: 23,076,223 (GRCm39) |
|
probably null |
Het |
|
| Other mutations in Sphkap |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00332:Sphkap
|
APN |
1 |
83,258,237 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL00337:Sphkap
|
APN |
1 |
83,317,329 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL00470:Sphkap
|
APN |
1 |
83,255,631 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
IGL00577:Sphkap
|
APN |
1 |
83,256,565 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL00657:Sphkap
|
APN |
1 |
83,254,096 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01868:Sphkap
|
APN |
1 |
83,258,120 (GRCm39) |
splice site |
probably null |
|
|
IGL02101:Sphkap
|
APN |
1 |
83,268,708 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02471:Sphkap
|
APN |
1 |
83,253,897 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02943:Sphkap
|
APN |
1 |
83,254,552 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02945:Sphkap
|
APN |
1 |
83,254,552 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03008:Sphkap
|
APN |
1 |
83,254,552 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03031:Sphkap
|
APN |
1 |
83,254,552 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03059:Sphkap
|
APN |
1 |
83,234,963 (GRCm39) |
missense |
probably damaging |
0.97 |
|
IGL03085:Sphkap
|
APN |
1 |
83,258,075 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
IGL03355:Sphkap
|
APN |
1 |
83,258,224 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03356:Sphkap
|
APN |
1 |
83,254,552 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03368:Sphkap
|
APN |
1 |
83,253,397 (GRCm39) |
missense |
probably benign |
0.14 |
|
R0294:Sphkap
|
UTSW |
1 |
83,255,966 (GRCm39) |
missense |
possibly damaging |
0.72 |
|
R0308:Sphkap
|
UTSW |
1 |
83,254,690 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0478:Sphkap
|
UTSW |
1 |
83,256,432 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0606:Sphkap
|
UTSW |
1 |
83,258,145 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0678:Sphkap
|
UTSW |
1 |
83,256,349 (GRCm39) |
missense |
probably benign |
0.03 |
|
R1216:Sphkap
|
UTSW |
1 |
83,268,698 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1253:Sphkap
|
UTSW |
1 |
83,256,619 (GRCm39) |
missense |
possibly damaging |
0.56 |
|
R1532:Sphkap
|
UTSW |
1 |
83,234,924 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1635:Sphkap
|
UTSW |
1 |
83,256,121 (GRCm39) |
missense |
probably benign |
0.03 |
|
R1655:Sphkap
|
UTSW |
1 |
83,255,236 (GRCm39) |
nonsense |
probably null |
|
|
R1657:Sphkap
|
UTSW |
1 |
83,255,236 (GRCm39) |
nonsense |
probably null |
|
|
R1700:Sphkap
|
UTSW |
1 |
83,255,236 (GRCm39) |
nonsense |
probably null |
|
|
R1701:Sphkap
|
UTSW |
1 |
83,255,236 (GRCm39) |
nonsense |
probably null |
|
|
R1734:Sphkap
|
UTSW |
1 |
83,255,236 (GRCm39) |
nonsense |
probably null |
|
|
R1736:Sphkap
|
UTSW |
1 |
83,255,236 (GRCm39) |
nonsense |
probably null |
|
|
R1743:Sphkap
|
UTSW |
1 |
83,255,236 (GRCm39) |
nonsense |
probably null |
|
|
R1744:Sphkap
|
UTSW |
1 |
83,255,236 (GRCm39) |
nonsense |
probably null |
|
|
R1760:Sphkap
|
UTSW |
1 |
83,255,265 (GRCm39) |
missense |
probably benign |
0.29 |
|
R1893:Sphkap
|
UTSW |
1 |
83,256,687 (GRCm39) |
missense |
probably benign |
0.02 |
|
R1937:Sphkap
|
UTSW |
1 |
83,245,162 (GRCm39) |
nonsense |
probably null |
|
|
R1986:Sphkap
|
UTSW |
1 |
83,255,643 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1993:Sphkap
|
UTSW |
1 |
83,255,236 (GRCm39) |
nonsense |
probably null |
|
|
R1995:Sphkap
|
UTSW |
1 |
83,255,236 (GRCm39) |
nonsense |
probably null |
|
|
R2004:Sphkap
|
UTSW |
1 |
83,255,632 (GRCm39) |
missense |
probably benign |
0.04 |
|
R2111:Sphkap
|
UTSW |
1 |
83,253,602 (GRCm39) |
missense |
probably benign |
0.00 |
|
R2112:Sphkap
|
UTSW |
1 |
83,253,602 (GRCm39) |
missense |
probably benign |
0.00 |
|
R2156:Sphkap
|
UTSW |
1 |
83,255,710 (GRCm39) |
missense |
probably benign |
0.03 |
|
R2182:Sphkap
|
UTSW |
1 |
83,254,405 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2271:Sphkap
|
UTSW |
1 |
83,234,942 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3712:Sphkap
|
UTSW |
1 |
83,254,833 (GRCm39) |
missense |
probably benign |
0.27 |
|
R3919:Sphkap
|
UTSW |
1 |
83,254,179 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3980:Sphkap
|
UTSW |
1 |
83,245,215 (GRCm39) |
splice site |
probably null |
|
|
R4130:Sphkap
|
UTSW |
1 |
83,255,619 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R4539:Sphkap
|
UTSW |
1 |
83,255,514 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4602:Sphkap
|
UTSW |
1 |
83,256,782 (GRCm39) |
nonsense |
probably null |
|
|
R4735:Sphkap
|
UTSW |
1 |
83,256,838 (GRCm39) |
missense |
probably benign |
0.01 |
|
R4793:Sphkap
|
UTSW |
1 |
83,255,805 (GRCm39) |
missense |
possibly damaging |
0.77 |
|
R4849:Sphkap
|
UTSW |
1 |
83,255,105 (GRCm39) |
missense |
probably benign |
0.03 |
|
R4880:Sphkap
|
UTSW |
1 |
83,266,538 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5213:Sphkap
|
UTSW |
1 |
83,258,224 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5277:Sphkap
|
UTSW |
1 |
83,253,885 (GRCm39) |
missense |
probably benign |
0.04 |
|
R5331:Sphkap
|
UTSW |
1 |
83,254,503 (GRCm39) |
missense |
probably benign |
0.08 |
|
R5632:Sphkap
|
UTSW |
1 |
83,256,006 (GRCm39) |
missense |
probably benign |
0.01 |
|
R5647:Sphkap
|
UTSW |
1 |
83,385,720 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R5751:Sphkap
|
UTSW |
1 |
83,253,618 (GRCm39) |
missense |
probably benign |
0.27 |
|
R5935:Sphkap
|
UTSW |
1 |
83,317,320 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5999:Sphkap
|
UTSW |
1 |
83,245,126 (GRCm39) |
missense |
probably benign |
0.02 |
|
R6232:Sphkap
|
UTSW |
1 |
83,258,200 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6318:Sphkap
|
UTSW |
1 |
83,256,099 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6474:Sphkap
|
UTSW |
1 |
83,256,544 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6602:Sphkap
|
UTSW |
1 |
83,253,479 (GRCm39) |
missense |
possibly damaging |
0.75 |
|
R6674:Sphkap
|
UTSW |
1 |
83,255,555 (GRCm39) |
missense |
probably benign |
0.37 |
|
R6716:Sphkap
|
UTSW |
1 |
83,339,949 (GRCm39) |
critical splice donor site |
probably null |
|
|
R6803:Sphkap
|
UTSW |
1 |
83,258,231 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6880:Sphkap
|
UTSW |
1 |
83,234,978 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6941:Sphkap
|
UTSW |
1 |
83,385,811 (GRCm39) |
start gained |
probably benign |
|
|
R7170:Sphkap
|
UTSW |
1 |
83,243,706 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7263:Sphkap
|
UTSW |
1 |
83,254,399 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7422:Sphkap
|
UTSW |
1 |
83,241,547 (GRCm39) |
missense |
probably benign |
0.02 |
|
R7640:Sphkap
|
UTSW |
1 |
83,256,649 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R7722:Sphkap
|
UTSW |
1 |
83,256,642 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7810:Sphkap
|
UTSW |
1 |
83,254,021 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7887:Sphkap
|
UTSW |
1 |
83,255,133 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7974:Sphkap
|
UTSW |
1 |
83,256,683 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7990:Sphkap
|
UTSW |
1 |
83,245,066 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8096:Sphkap
|
UTSW |
1 |
83,255,279 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R8110:Sphkap
|
UTSW |
1 |
83,256,492 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
R8125:Sphkap
|
UTSW |
1 |
83,241,303 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8153:Sphkap
|
UTSW |
1 |
83,255,730 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R8245:Sphkap
|
UTSW |
1 |
83,256,492 (GRCm39) |
missense |
probably benign |
0.14 |
|
R8394:Sphkap
|
UTSW |
1 |
83,253,797 (GRCm39) |
missense |
probably benign |
0.08 |
|
R8443:Sphkap
|
UTSW |
1 |
83,255,953 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8508:Sphkap
|
UTSW |
1 |
83,254,221 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8531:Sphkap
|
UTSW |
1 |
83,254,909 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8673:Sphkap
|
UTSW |
1 |
83,253,561 (GRCm39) |
missense |
probably benign |
0.01 |
|
R8674:Sphkap
|
UTSW |
1 |
83,255,565 (GRCm39) |
missense |
probably benign |
0.04 |
|
R8682:Sphkap
|
UTSW |
1 |
83,256,997 (GRCm39) |
missense |
probably benign |
0.21 |
|
R8837:Sphkap
|
UTSW |
1 |
83,253,384 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
R8857:Sphkap
|
UTSW |
1 |
83,258,288 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8902:Sphkap
|
UTSW |
1 |
83,256,685 (GRCm39) |
missense |
probably benign |
0.21 |
|
R8916:Sphkap
|
UTSW |
1 |
83,255,108 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
R8944:Sphkap
|
UTSW |
1 |
83,256,927 (GRCm39) |
missense |
probably benign |
0.39 |
|
R9154:Sphkap
|
UTSW |
1 |
83,234,982 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9579:Sphkap
|
UTSW |
1 |
83,255,295 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9616:Sphkap
|
UTSW |
1 |
83,254,989 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9781:Sphkap
|
UTSW |
1 |
83,255,772 (GRCm39) |
missense |
possibly damaging |
0.62 |
|
Z1088:Sphkap
|
UTSW |
1 |
83,256,325 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1088:Sphkap
|
UTSW |
1 |
83,254,329 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1176:Sphkap
|
UTSW |
1 |
83,258,163 (GRCm39) |
missense |
possibly damaging |
0.61 |
|
Z1176:Sphkap
|
UTSW |
1 |
83,253,754 (GRCm39) |
nonsense |
probably null |
|
|
Z1177:Sphkap
|
UTSW |
1 |
83,254,152 (GRCm39) |
missense |
probably damaging |
0.96 |
|
| Predicted Primers |
PCR Primer
(F):5'- TCGCGATGTCCCTTAACATG -3'
(R):5'- TCACAGAGTTTTCCATGGTGG -3'
Sequencing Primer
(F):5'- CGATGTCCCTTAACATGTACCTATAG -3'
(R):5'- AAGGCCAGAGTTGTTCCCG -3'
|
| Posted On |
2014-08-25 |
Incidental Mutation