Incidental Mutation 'R2001:Pzp'
| ID |
225929 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Pzp
|
| Ensembl Gene |
ENSMUSG00000030359 |
| Gene Name |
PZP, alpha-2-macroglobulin like |
| Synonyms |
|
| MMRRC Submission |
040011-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.118)
|
| Stock # |
R2001 (G1)
|
| Quality Score |
225 |
|
Status
|
Not validated
|
| Chromosome |
6 |
| Chromosomal Location |
128460530-128503683 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to C
at 128493083 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Threonine to Alanine
at position 352
(T352A)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000107760
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000112132]
|
| AlphaFold |
Q61838 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000032510
AA Change: T352A
PolyPhen 2
Score 0.003 (Sensitivity: 0.98; Specificity: 0.44)
|
| SMART Domains |
Protein: ENSMUSP00000032510
Gene: ENSMUSG00000030359
AA Change: T352A
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
11 |
18 |
N/A |
INTRINSIC |
|
Pfam:A2M_N
|
126 |
219 |
8.8e-22 |
PFAM |
|
low complexity region
|
327 |
338 |
N/A |
INTRINSIC |
|
A2M_N_2
|
458 |
606 |
6.18e-40 |
SMART |
|
A2M
|
750 |
840 |
2.27e-38 |
SMART |
|
Pfam:Thiol-ester_cl
|
973 |
1002 |
5.7e-19 |
PFAM |
|
Pfam:A2M_comp
|
1022 |
1284 |
1.6e-93 |
PFAM |
|
A2M_recep
|
1395 |
1482 |
6.47e-43 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000112132
AA Change: T352A
PolyPhen 2
Score 0.011 (Sensitivity: 0.96; Specificity: 0.78)
|
| SMART Domains |
Protein: ENSMUSP00000107760
Gene: ENSMUSG00000030359
AA Change: T352A
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
11 |
18 |
N/A |
INTRINSIC |
|
Pfam:A2M_N
|
126 |
219 |
3.2e-23 |
PFAM |
|
low complexity region
|
327 |
338 |
N/A |
INTRINSIC |
|
A2M_N_2
|
458 |
606 |
6.18e-40 |
SMART |
|
A2M
|
750 |
840 |
2.27e-38 |
SMART |
|
Pfam:Thiol-ester_cl
|
973 |
1003 |
4e-19 |
PFAM |
|
Pfam:A2M_comp
|
1022 |
1284 |
2.1e-90 |
PFAM |
|
A2M_recep
|
1395 |
1482 |
6.47e-43 |
SMART |
|
| Coding Region Coverage |
- 1x: 99.2%
- 3x: 98.6%
- 10x: 97.1%
- 20x: 94.6%
|
| Validation Efficiency |
|
| MGI Phenotype |
PHENOTYPE: Homozygotes mutant null mice show higher bone mineral density, hypoactivity, and decreased heart rate. Mice homozygous for a different null allele show resistance to the lethal effects of endotoxin, increased susceptibility to diet-induced acute pancreatitis, and altered LPS-induced febrile and cytokine responses. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 96 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 4932414N04Rik |
T |
C |
2: 68,571,800 (GRCm39) |
S559P |
probably benign |
Het |
| A430005L14Rik |
T |
A |
4: 154,044,314 (GRCm39) |
C42S |
probably damaging |
Het |
| Abca13 |
A |
T |
11: 9,223,967 (GRCm39) |
T449S |
probably benign |
Het |
| Acvr1c |
T |
A |
2: 58,205,987 (GRCm39) |
Q41L |
probably benign |
Het |
| Adamts13 |
C |
T |
2: 26,864,002 (GRCm39) |
P60L |
probably benign |
Het |
| Adamts20 |
T |
C |
15: 94,245,599 (GRCm39) |
T568A |
possibly damaging |
Het |
| Ago1 |
T |
C |
4: 126,348,187 (GRCm39) |
I44V |
probably null |
Het |
| Agtpbp1 |
TGAAGATGCATCTTGAGAAGA |
TGAAGA |
13: 59,623,617 (GRCm39) |
|
probably null |
Het |
| Ankrd28 |
A |
T |
14: 31,467,293 (GRCm39) |
V39E |
possibly damaging |
Het |
| Apaf1 |
A |
G |
10: 90,897,676 (GRCm39) |
V269A |
possibly damaging |
Het |
| Astn1 |
A |
G |
1: 158,348,091 (GRCm39) |
N506D |
probably damaging |
Het |
| BC051019 |
G |
A |
7: 109,319,758 (GRCm39) |
Q102* |
probably null |
Het |
| Bpifb5 |
A |
G |
2: 154,075,199 (GRCm39) |
T376A |
possibly damaging |
Het |
| Ccdc121rt1 |
G |
T |
1: 181,338,551 (GRCm39) |
Q134K |
probably benign |
Het |
| Ccl20 |
ATT |
ATTT |
1: 83,095,576 (GRCm39) |
|
probably null |
Het |
| Ccl6 |
G |
T |
11: 83,480,163 (GRCm39) |
P68T |
possibly damaging |
Het |
| Cd300ld |
A |
T |
11: 114,878,156 (GRCm39) |
F119I |
probably benign |
Het |
| Cdk2ap2 |
A |
G |
19: 4,147,903 (GRCm39) |
M57V |
possibly damaging |
Het |
| Cemip2 |
A |
G |
19: 21,779,351 (GRCm39) |
D387G |
probably benign |
Het |
| Chkb |
C |
T |
15: 89,312,969 (GRCm39) |
G36E |
probably damaging |
Het |
| Col11a1 |
A |
G |
3: 113,958,942 (GRCm39) |
|
probably null |
Het |
| Ctla2b |
T |
C |
13: 61,043,881 (GRCm39) |
Y120C |
probably damaging |
Het |
| Ctnnd1 |
T |
C |
2: 84,450,704 (GRCm39) |
N172S |
probably benign |
Het |
| Cyp2a22 |
G |
A |
7: 26,634,197 (GRCm39) |
P319L |
probably damaging |
Het |
| Dcaf12 |
A |
C |
4: 41,302,804 (GRCm39) |
V117G |
probably damaging |
Het |
| Ddx6 |
A |
G |
9: 44,518,831 (GRCm39) |
T48A |
probably benign |
Het |
| Dgki |
T |
C |
6: 36,842,736 (GRCm39) |
D923G |
possibly damaging |
Het |
| Dhx37 |
G |
T |
5: 125,504,528 (GRCm39) |
T345K |
probably damaging |
Het |
| Dhx9 |
A |
T |
1: 153,331,857 (GRCm39) |
Y1370* |
probably null |
Het |
| Dnah7b |
T |
C |
1: 46,181,247 (GRCm39) |
S1045P |
possibly damaging |
Het |
| Dnmbp |
G |
C |
19: 43,838,612 (GRCm39) |
T1071S |
possibly damaging |
Het |
| Dspp |
T |
A |
5: 104,326,425 (GRCm39) |
S929R |
unknown |
Het |
| Dst |
A |
T |
1: 34,223,144 (GRCm39) |
E1625D |
probably damaging |
Het |
| Egflam |
T |
A |
15: 7,272,048 (GRCm39) |
H630L |
probably benign |
Het |
| Elane |
T |
C |
10: 79,723,593 (GRCm39) |
V186A |
possibly damaging |
Het |
| Fam209 |
C |
A |
2: 172,314,689 (GRCm39) |
N59K |
probably benign |
Het |
| Gbe1 |
A |
G |
16: 70,325,814 (GRCm39) |
E617G |
probably damaging |
Het |
| Get3 |
T |
C |
8: 85,751,789 (GRCm39) |
S36G |
probably damaging |
Het |
| Gfra1 |
A |
G |
19: 58,288,707 (GRCm39) |
L246P |
probably damaging |
Het |
| Gria2 |
T |
C |
3: 80,618,112 (GRCm39) |
T308A |
probably benign |
Het |
| Grip2 |
A |
T |
6: 91,756,831 (GRCm39) |
V540D |
probably benign |
Het |
| Hhipl1 |
A |
T |
12: 108,288,118 (GRCm39) |
I575F |
possibly damaging |
Het |
| Hmcn1 |
T |
A |
1: 150,614,364 (GRCm39) |
E1347D |
possibly damaging |
Het |
| Itga2b |
C |
A |
11: 102,358,165 (GRCm39) |
A187S |
probably benign |
Het |
| Kalrn |
C |
A |
16: 33,848,415 (GRCm39) |
R469M |
probably damaging |
Het |
| Kif23 |
A |
T |
9: 61,834,666 (GRCm39) |
C426* |
probably null |
Het |
| Lck |
T |
C |
4: 129,442,730 (GRCm39) |
N475S |
probably benign |
Het |
| Leng8 |
A |
G |
7: 4,148,073 (GRCm39) |
N642S |
probably damaging |
Het |
| Lingo4 |
T |
A |
3: 94,310,382 (GRCm39) |
I440N |
probably damaging |
Het |
| Lrrc4 |
A |
G |
6: 28,830,904 (GRCm39) |
F237S |
probably damaging |
Het |
| Magel2 |
G |
A |
7: 62,028,844 (GRCm39) |
V583I |
unknown |
Het |
| Naip2 |
A |
T |
13: 100,281,096 (GRCm39) |
I1316N |
probably damaging |
Het |
| Naip6 |
C |
T |
13: 100,437,237 (GRCm39) |
G429S |
probably benign |
Het |
| Noct |
C |
T |
3: 51,155,465 (GRCm39) |
R78C |
probably damaging |
Het |
| Npbwr1 |
A |
G |
1: 5,987,394 (GRCm39) |
V40A |
possibly damaging |
Het |
| Nsd2 |
A |
G |
5: 34,000,746 (GRCm39) |
N88D |
probably damaging |
Het |
| Or1e29 |
T |
A |
11: 73,667,539 (GRCm39) |
I205F |
probably benign |
Het |
| Or5ap2 |
T |
A |
2: 85,680,744 (GRCm39) |
V316E |
probably benign |
Het |
| Or6c210 |
T |
A |
10: 129,496,290 (GRCm39) |
I205N |
probably benign |
Het |
| Or8k28 |
T |
C |
2: 86,285,817 (GRCm39) |
H266R |
probably benign |
Het |
| Pak5 |
T |
A |
2: 135,958,557 (GRCm39) |
H177L |
probably benign |
Het |
| Pard3 |
C |
T |
8: 127,791,097 (GRCm39) |
|
probably null |
Het |
| Pde4c |
A |
G |
8: 71,200,007 (GRCm39) |
|
probably null |
Het |
| Pde6h |
T |
A |
6: 136,940,203 (GRCm39) |
I63N |
probably damaging |
Het |
| Phldb2 |
T |
C |
16: 45,594,558 (GRCm39) |
K916E |
possibly damaging |
Het |
| Ppig |
T |
C |
2: 69,571,988 (GRCm39) |
S236P |
unknown |
Het |
| Ptprd |
T |
C |
4: 75,872,359 (GRCm39) |
Y1370C |
probably damaging |
Het |
| Rab3gap1 |
A |
G |
1: 127,831,456 (GRCm39) |
Y177C |
possibly damaging |
Het |
| Rasgef1a |
G |
A |
6: 118,066,157 (GRCm39) |
V457M |
probably benign |
Het |
| Scel |
A |
T |
14: 103,848,226 (GRCm39) |
T616S |
possibly damaging |
Het |
| Sel1l |
A |
T |
12: 91,793,324 (GRCm39) |
Y228* |
probably null |
Het |
| Sgms1 |
A |
G |
19: 32,137,083 (GRCm39) |
V161A |
possibly damaging |
Het |
| Slfnl1 |
T |
C |
4: 120,390,424 (GRCm39) |
L25P |
probably benign |
Het |
| Smad5 |
A |
G |
13: 56,885,187 (GRCm39) |
T432A |
probably damaging |
Het |
| Sohlh2 |
T |
C |
3: 55,099,762 (GRCm39) |
|
probably null |
Het |
| Sphkap |
A |
T |
1: 83,254,383 (GRCm39) |
M835K |
probably damaging |
Het |
| Sqor |
A |
C |
2: 122,640,018 (GRCm39) |
T174P |
probably damaging |
Het |
| Stkld1 |
T |
C |
2: 26,842,759 (GRCm39) |
V577A |
probably damaging |
Het |
| Sulf2 |
T |
A |
2: 165,922,773 (GRCm39) |
E652D |
probably benign |
Het |
| Sycp2 |
T |
A |
2: 178,019,848 (GRCm39) |
Q556L |
probably benign |
Het |
| Syk |
A |
G |
13: 52,765,274 (GRCm39) |
T134A |
probably benign |
Het |
| Tas2r122 |
T |
A |
6: 132,688,585 (GRCm39) |
I103F |
possibly damaging |
Het |
| Tex10 |
A |
G |
4: 48,451,940 (GRCm39) |
W729R |
probably damaging |
Het |
| Tex261 |
G |
T |
6: 83,750,713 (GRCm39) |
P95T |
probably damaging |
Het |
| Tm2d2 |
T |
C |
8: 25,507,523 (GRCm39) |
S47P |
probably benign |
Het |
| Tmem95 |
A |
G |
11: 69,767,817 (GRCm39) |
S128P |
probably damaging |
Het |
| Tnxb |
G |
A |
17: 34,911,553 (GRCm39) |
A1619T |
possibly damaging |
Het |
| Trappc9 |
A |
G |
15: 72,929,885 (GRCm39) |
I157T |
probably damaging |
Het |
| Unc13c |
T |
A |
9: 73,390,897 (GRCm39) |
|
probably null |
Het |
| Upb1 |
A |
T |
10: 75,265,803 (GRCm39) |
Y210F |
probably damaging |
Het |
| Urb1 |
T |
C |
16: 90,559,232 (GRCm39) |
M1684V |
probably benign |
Het |
| Wnk2 |
G |
A |
13: 49,232,158 (GRCm39) |
P727S |
possibly damaging |
Het |
| Zfp1004 |
T |
A |
2: 150,034,867 (GRCm39) |
M396K |
probably benign |
Het |
| Zfp551 |
A |
T |
7: 12,150,276 (GRCm39) |
S378T |
probably damaging |
Het |
| Zfp598 |
T |
C |
17: 24,888,898 (GRCm39) |
V56A |
possibly damaging |
Het |
| Zfp945 |
C |
T |
17: 23,076,223 (GRCm39) |
|
probably null |
Het |
|
| Other mutations in Pzp |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00337:Pzp
|
APN |
6 |
128,493,872 (GRCm39) |
missense |
probably benign |
0.25 |
|
IGL01470:Pzp
|
APN |
6 |
128,498,087 (GRCm39) |
missense |
probably benign |
0.05 |
|
IGL01753:Pzp
|
APN |
6 |
128,479,146 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
IGL01878:Pzp
|
APN |
6 |
128,472,261 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02307:Pzp
|
APN |
6 |
128,466,049 (GRCm39) |
nonsense |
probably null |
|
|
IGL02338:Pzp
|
APN |
6 |
128,463,133 (GRCm39) |
missense |
probably benign |
0.07 |
|
IGL02546:Pzp
|
APN |
6 |
128,471,662 (GRCm39) |
splice site |
probably benign |
|
|
IGL02598:Pzp
|
APN |
6 |
128,464,420 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL02699:Pzp
|
APN |
6 |
128,464,364 (GRCm39) |
critical splice donor site |
probably null |
|
|
lilibet
|
UTSW |
6 |
128,490,736 (GRCm39) |
missense |
probably damaging |
0.99 |
|
P4748:Pzp
|
UTSW |
6 |
128,467,052 (GRCm39) |
missense |
probably damaging |
1.00 |
|
PIT4151001:Pzp
|
UTSW |
6 |
128,502,259 (GRCm39) |
missense |
probably benign |
0.34 |
|
PIT4495001:Pzp
|
UTSW |
6 |
128,479,192 (GRCm39) |
missense |
probably benign |
|
|
R0157:Pzp
|
UTSW |
6 |
128,500,939 (GRCm39) |
nonsense |
probably null |
|
|
R0195:Pzp
|
UTSW |
6 |
128,464,441 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0238:Pzp
|
UTSW |
6 |
128,466,119 (GRCm39) |
splice site |
probably benign |
|
|
R0239:Pzp
|
UTSW |
6 |
128,466,119 (GRCm39) |
splice site |
probably benign |
|
|
R0271:Pzp
|
UTSW |
6 |
128,496,477 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0299:Pzp
|
UTSW |
6 |
128,472,293 (GRCm39) |
splice site |
probably benign |
|
|
R0744:Pzp
|
UTSW |
6 |
128,493,158 (GRCm39) |
unclassified |
probably benign |
|
|
R0968:Pzp
|
UTSW |
6 |
128,502,108 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1037:Pzp
|
UTSW |
6 |
128,496,389 (GRCm39) |
missense |
probably benign |
0.01 |
|
R1074:Pzp
|
UTSW |
6 |
128,464,887 (GRCm39) |
missense |
probably benign |
0.20 |
|
R1469:Pzp
|
UTSW |
6 |
128,489,319 (GRCm39) |
missense |
probably benign |
0.04 |
|
R1469:Pzp
|
UTSW |
6 |
128,489,319 (GRCm39) |
missense |
probably benign |
0.04 |
|
R1579:Pzp
|
UTSW |
6 |
128,500,931 (GRCm39) |
critical splice donor site |
probably null |
|
|
R1646:Pzp
|
UTSW |
6 |
128,480,518 (GRCm39) |
missense |
probably benign |
0.33 |
|
R1770:Pzp
|
UTSW |
6 |
128,462,580 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1777:Pzp
|
UTSW |
6 |
128,467,535 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R1786:Pzp
|
UTSW |
6 |
128,468,124 (GRCm39) |
splice site |
probably null |
|
|
R1854:Pzp
|
UTSW |
6 |
128,479,188 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2060:Pzp
|
UTSW |
6 |
128,460,673 (GRCm39) |
missense |
probably benign |
0.45 |
|
R2081:Pzp
|
UTSW |
6 |
128,496,383 (GRCm39) |
missense |
probably benign |
0.00 |
|
R2130:Pzp
|
UTSW |
6 |
128,468,124 (GRCm39) |
splice site |
probably null |
|
|
R2131:Pzp
|
UTSW |
6 |
128,468,124 (GRCm39) |
splice site |
probably null |
|
|
R2160:Pzp
|
UTSW |
6 |
128,502,239 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2168:Pzp
|
UTSW |
6 |
128,465,010 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R2328:Pzp
|
UTSW |
6 |
128,487,353 (GRCm39) |
missense |
possibly damaging |
0.79 |
|
R2441:Pzp
|
UTSW |
6 |
128,466,731 (GRCm39) |
nonsense |
probably null |
|
|
R2866:Pzp
|
UTSW |
6 |
128,502,227 (GRCm39) |
missense |
possibly damaging |
0.76 |
|
R2869:Pzp
|
UTSW |
6 |
128,462,519 (GRCm39) |
critical splice donor site |
probably null |
|
|
R2869:Pzp
|
UTSW |
6 |
128,462,519 (GRCm39) |
critical splice donor site |
probably null |
|
|
R2870:Pzp
|
UTSW |
6 |
128,462,519 (GRCm39) |
critical splice donor site |
probably null |
|
|
R2870:Pzp
|
UTSW |
6 |
128,462,519 (GRCm39) |
critical splice donor site |
probably null |
|
|
R2873:Pzp
|
UTSW |
6 |
128,462,519 (GRCm39) |
critical splice donor site |
probably null |
|
|
R2876:Pzp
|
UTSW |
6 |
128,468,513 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3404:Pzp
|
UTSW |
6 |
128,490,769 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4452:Pzp
|
UTSW |
6 |
128,468,203 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4461:Pzp
|
UTSW |
6 |
128,501,003 (GRCm39) |
missense |
probably benign |
0.02 |
|
R5103:Pzp
|
UTSW |
6 |
128,479,192 (GRCm39) |
missense |
probably benign |
0.04 |
|
R5193:Pzp
|
UTSW |
6 |
128,479,297 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5425:Pzp
|
UTSW |
6 |
128,466,011 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R5465:Pzp
|
UTSW |
6 |
128,463,924 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5590:Pzp
|
UTSW |
6 |
128,500,759 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5656:Pzp
|
UTSW |
6 |
128,467,035 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5697:Pzp
|
UTSW |
6 |
128,502,152 (GRCm39) |
missense |
probably benign |
0.03 |
|
R5854:Pzp
|
UTSW |
6 |
128,483,832 (GRCm39) |
missense |
probably benign |
0.01 |
|
R5994:Pzp
|
UTSW |
6 |
128,468,560 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6042:Pzp
|
UTSW |
6 |
128,500,977 (GRCm39) |
missense |
possibly damaging |
0.75 |
|
R6054:Pzp
|
UTSW |
6 |
128,490,727 (GRCm39) |
missense |
probably benign |
0.03 |
|
R6153:Pzp
|
UTSW |
6 |
128,465,979 (GRCm39) |
missense |
probably benign |
|
|
R6465:Pzp
|
UTSW |
6 |
128,468,582 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6719:Pzp
|
UTSW |
6 |
128,501,046 (GRCm39) |
missense |
probably benign |
0.17 |
|
R6722:Pzp
|
UTSW |
6 |
128,464,917 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7316:Pzp
|
UTSW |
6 |
128,490,736 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7453:Pzp
|
UTSW |
6 |
128,463,879 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7826:Pzp
|
UTSW |
6 |
128,464,496 (GRCm39) |
missense |
probably benign |
0.38 |
|
R7878:Pzp
|
UTSW |
6 |
128,489,274 (GRCm39) |
missense |
possibly damaging |
0.50 |
|
R7879:Pzp
|
UTSW |
6 |
128,465,979 (GRCm39) |
missense |
probably benign |
|
|
R8113:Pzp
|
UTSW |
6 |
128,490,694 (GRCm39) |
splice site |
probably null |
|
|
R8163:Pzp
|
UTSW |
6 |
128,489,157 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8471:Pzp
|
UTSW |
6 |
128,464,411 (GRCm39) |
missense |
probably benign |
0.14 |
|
R8680:Pzp
|
UTSW |
6 |
128,473,009 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8795:Pzp
|
UTSW |
6 |
128,471,701 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8844:Pzp
|
UTSW |
6 |
128,500,950 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8964:Pzp
|
UTSW |
6 |
128,464,462 (GRCm39) |
missense |
probably benign |
0.05 |
|
R9043:Pzp
|
UTSW |
6 |
128,471,742 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9172:Pzp
|
UTSW |
6 |
128,502,172 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9205:Pzp
|
UTSW |
6 |
128,473,626 (GRCm39) |
missense |
probably benign |
0.02 |
|
R9276:Pzp
|
UTSW |
6 |
128,499,077 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9432:Pzp
|
UTSW |
6 |
128,499,128 (GRCm39) |
missense |
|
|
|
R9444:Pzp
|
UTSW |
6 |
128,487,362 (GRCm39) |
missense |
|
|
|
R9517:Pzp
|
UTSW |
6 |
128,489,117 (GRCm39) |
critical splice donor site |
probably null |
|
|
R9721:Pzp
|
UTSW |
6 |
128,472,154 (GRCm39) |
critical splice donor site |
probably null |
|
|
| Predicted Primers |
PCR Primer
(F):5'- CAAGTGAGAGATCCTGCCTC -3'
(R):5'- TTGTAGCATCCTATAGTAACAGAGG -3'
Sequencing Primer
(F):5'- TCCTGCCTCAATGAATAAGGTAGAG -3'
(R):5'- CATCCTATAGTAACAGAGGAGAGCTG -3'
|
| Posted On |
2014-08-25 |
Incidental Mutation