Incidental Mutation 'R2129:Lrriq1'
| ID |
227860 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Lrriq1
|
| Ensembl Gene |
ENSMUSG00000019892 |
| Gene Name |
leucine-rich repeats and IQ motif containing 1 |
| Synonyms |
Gm1557, LOC380658, 4930503E15Rik |
| MMRRC Submission |
040132-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.073)
|
| Stock # |
R2129 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
|
| Chromosome |
10 |
| Chromosomal Location |
102881892-103072183 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
G to A
at 103050718 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Threonine to Isoleucine
at position 678
(T678I)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000131419
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000020043]
[ENSMUST00000123364]
[ENSMUST00000166240]
|
| AlphaFold |
Q0P5X1 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000020043
AA Change: T678I
PolyPhen 2
Score 0.007 (Sensitivity: 0.96; Specificity: 0.75)
|
| SMART Domains |
Protein: ENSMUSP00000020043
Gene: ENSMUSG00000019892
AA Change: T678I
| Domain | Start | End | E-Value | Type |
|---|
|
coiled coil region
|
11 |
31 |
N/A |
INTRINSIC |
|
low complexity region
|
35 |
48 |
N/A |
INTRINSIC |
|
coiled coil region
|
183 |
286 |
N/A |
INTRINSIC |
|
Blast:IQ
|
290 |
312 |
1e-6 |
BLAST |
|
coiled coil region
|
314 |
390 |
N/A |
INTRINSIC |
|
low complexity region
|
550 |
559 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000123364
|
| SMART Domains |
Protein: ENSMUSP00000119783
Gene: ENSMUSG00000019892
| Domain | Start | End | E-Value | Type |
|---|
|
coiled coil region
|
11 |
31 |
N/A |
INTRINSIC |
|
low complexity region
|
35 |
48 |
N/A |
INTRINSIC |
|
coiled coil region
|
183 |
286 |
N/A |
INTRINSIC |
|
Blast:IQ
|
290 |
312 |
6e-6 |
BLAST |
|
coiled coil region
|
314 |
390 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000166240
AA Change: T678I
PolyPhen 2
Score 0.007 (Sensitivity: 0.96; Specificity: 0.75)
|
| SMART Domains |
Protein: ENSMUSP00000131419
Gene: ENSMUSG00000019892
AA Change: T678I
| Domain | Start | End | E-Value | Type |
|---|
|
coiled coil region
|
11 |
31 |
N/A |
INTRINSIC |
|
low complexity region
|
35 |
48 |
N/A |
INTRINSIC |
|
coiled coil region
|
183 |
286 |
N/A |
INTRINSIC |
|
IQ
|
290 |
312 |
9.78e1 |
SMART |
|
coiled coil region
|
314 |
390 |
N/A |
INTRINSIC |
|
low complexity region
|
550 |
559 |
N/A |
INTRINSIC |
|
LRR
|
873 |
894 |
2.14e1 |
SMART |
|
LRR
|
895 |
917 |
4.45e1 |
SMART |
|
LRR
|
984 |
1005 |
2.03e2 |
SMART |
|
LRR
|
1029 |
1052 |
3.65e0 |
SMART |
|
low complexity region
|
1244 |
1258 |
N/A |
INTRINSIC |
|
IQ
|
1279 |
1301 |
5.61e1 |
SMART |
|
IQ
|
1339 |
1361 |
6.7e-3 |
SMART |
|
low complexity region
|
1369 |
1394 |
N/A |
INTRINSIC |
|
low complexity region
|
1502 |
1518 |
N/A |
INTRINSIC |
|
low complexity region
|
1528 |
1543 |
N/A |
INTRINSIC |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000220380
|
| Meta Mutation Damage Score |
0.0898 |
| Coding Region Coverage |
- 1x: 99.2%
- 3x: 98.6%
- 10x: 97.3%
- 20x: 95.1%
|
| Validation Efficiency |
99% (91/92) |
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 91 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 1700113H08Rik |
A |
G |
10: 87,066,066 (GRCm39) |
E249G |
possibly damaging |
Het |
| 2610028H24Rik |
A |
G |
10: 76,293,349 (GRCm39) |
M136V |
possibly damaging |
Het |
| 4930523C07Rik |
A |
T |
1: 159,902,945 (GRCm39) |
K72* |
probably null |
Het |
| Abhd14a |
A |
T |
9: 106,318,064 (GRCm39) |
L125Q |
probably null |
Het |
| Abhd17b |
T |
A |
19: 21,658,413 (GRCm39) |
|
probably null |
Het |
| Abo |
G |
A |
2: 26,736,586 (GRCm39) |
T61I |
probably benign |
Het |
| Adamts15 |
T |
C |
9: 30,815,799 (GRCm39) |
T686A |
probably benign |
Het |
| Adgrv1 |
A |
T |
13: 81,705,199 (GRCm39) |
F1537Y |
probably damaging |
Het |
| Anxa2 |
A |
T |
9: 69,383,410 (GRCm39) |
Y75F |
possibly damaging |
Het |
| Aqp3 |
T |
A |
4: 41,098,061 (GRCm39) |
I17F |
probably benign |
Het |
| Aspm |
T |
C |
1: 139,385,373 (GRCm39) |
V339A |
probably benign |
Het |
| Bri3bp |
T |
A |
5: 125,528,735 (GRCm39) |
L48* |
probably null |
Het |
| Car7 |
T |
A |
8: 105,275,605 (GRCm39) |
C185S |
possibly damaging |
Het |
| Casp8ap2 |
T |
C |
4: 32,640,142 (GRCm39) |
Y399H |
probably benign |
Het |
| Ces4a |
G |
A |
8: 105,864,729 (GRCm39) |
G69S |
probably damaging |
Het |
| Chst10 |
A |
G |
1: 38,904,776 (GRCm39) |
Y203H |
probably benign |
Het |
| Clca3a1 |
T |
C |
3: 144,722,526 (GRCm39) |
D282G |
probably damaging |
Het |
| Coq3 |
T |
G |
4: 21,900,342 (GRCm39) |
S190A |
probably benign |
Het |
| Crocc |
G |
A |
4: 140,744,407 (GRCm39) |
R1830C |
probably damaging |
Het |
| Cygb |
A |
G |
11: 116,540,668 (GRCm39) |
L106P |
probably damaging |
Het |
| Dab2 |
G |
T |
15: 6,365,864 (GRCm39) |
E87* |
probably null |
Het |
| Dcst1 |
T |
A |
3: 89,264,852 (GRCm39) |
I299F |
probably damaging |
Het |
| Dennd4a |
T |
G |
9: 64,813,256 (GRCm39) |
|
probably null |
Het |
| Depdc7 |
A |
G |
2: 104,558,518 (GRCm39) |
S168P |
probably benign |
Het |
| Dicer1 |
G |
A |
12: 104,688,290 (GRCm39) |
T429I |
probably damaging |
Het |
| Dnah5 |
A |
G |
15: 28,408,467 (GRCm39) |
Q3484R |
probably benign |
Het |
| Dock2 |
T |
C |
11: 34,618,242 (GRCm39) |
M125V |
probably damaging |
Het |
| Dync2h1 |
A |
G |
9: 7,175,289 (GRCm39) |
S107P |
possibly damaging |
Het |
| Emb |
T |
C |
13: 117,404,082 (GRCm39) |
V278A |
probably damaging |
Het |
| Firrm |
T |
C |
1: 163,794,026 (GRCm39) |
Y518C |
probably damaging |
Het |
| Foxk1 |
C |
A |
5: 142,420,943 (GRCm39) |
S189* |
probably null |
Het |
| Galm |
T |
C |
17: 80,490,647 (GRCm39) |
I268T |
probably benign |
Het |
| Gm5581 |
A |
C |
6: 131,145,247 (GRCm39) |
|
noncoding transcript |
Het |
| Gpr6 |
G |
A |
10: 40,947,168 (GRCm39) |
S138L |
possibly damaging |
Het |
| Hesx1 |
C |
A |
14: 26,722,802 (GRCm39) |
H42Q |
possibly damaging |
Het |
| Hsp90b1 |
T |
C |
10: 86,531,570 (GRCm39) |
D421G |
probably damaging |
Het |
| Kctd19 |
T |
C |
8: 106,111,804 (GRCm39) |
T31A |
probably damaging |
Het |
| Kif1b |
G |
A |
4: 149,272,097 (GRCm39) |
S1568L |
possibly damaging |
Het |
| Krtap19-3 |
T |
C |
16: 88,674,863 (GRCm39) |
|
probably benign |
Het |
| Lin28a |
T |
A |
4: 133,745,465 (GRCm39) |
I43F |
probably benign |
Het |
| Macf1 |
A |
G |
4: 123,262,608 (GRCm39) |
|
probably benign |
Het |
| Madcam1 |
A |
G |
10: 79,501,406 (GRCm39) |
E157G |
possibly damaging |
Het |
| Mctp1 |
A |
G |
13: 76,972,941 (GRCm39) |
D648G |
probably damaging |
Het |
| Megf8 |
T |
C |
7: 25,030,140 (GRCm39) |
L425P |
probably damaging |
Het |
| Mospd4 |
A |
G |
18: 46,598,731 (GRCm39) |
|
noncoding transcript |
Het |
| Mybpc1 |
T |
G |
10: 88,387,314 (GRCm39) |
T466P |
probably damaging |
Het |
| Myo10 |
T |
C |
15: 25,781,885 (GRCm39) |
Y1127H |
probably benign |
Het |
| Myo18b |
A |
T |
5: 112,978,944 (GRCm39) |
L1223Q |
probably damaging |
Het |
| Myo9b |
T |
C |
8: 71,786,343 (GRCm39) |
Y670H |
probably damaging |
Het |
| Ndufaf4 |
G |
T |
4: 24,898,608 (GRCm39) |
D55Y |
probably damaging |
Het |
| Neurod2 |
G |
T |
11: 98,218,414 (GRCm39) |
A250E |
possibly damaging |
Het |
| Nherf1 |
A |
T |
11: 115,067,270 (GRCm39) |
I174F |
probably damaging |
Het |
| Nipsnap1 |
C |
A |
11: 4,838,932 (GRCm39) |
N119K |
probably benign |
Het |
| Npffr2 |
A |
T |
5: 89,715,924 (GRCm39) |
I84F |
probably damaging |
Het |
| Or10ab4 |
T |
A |
7: 107,655,111 (GRCm39) |
N307K |
probably benign |
Het |
| Or11h23 |
A |
G |
14: 50,948,093 (GRCm39) |
Y102C |
probably damaging |
Het |
| Or2t48 |
T |
C |
11: 58,420,437 (GRCm39) |
D125G |
probably damaging |
Het |
| Pald1 |
A |
G |
10: 61,184,085 (GRCm39) |
|
probably null |
Het |
| Palld |
T |
C |
8: 62,330,395 (GRCm39) |
S161G |
probably benign |
Het |
| Paqr9 |
T |
A |
9: 95,443,122 (GRCm39) |
F371I |
probably benign |
Het |
| Pear1 |
A |
T |
3: 87,665,666 (GRCm39) |
C120* |
probably null |
Het |
| Pla2g4e |
A |
T |
2: 120,013,292 (GRCm39) |
F343I |
probably damaging |
Het |
| Plxdc2 |
A |
T |
2: 16,516,902 (GRCm39) |
Y61F |
probably benign |
Het |
| Polh |
G |
A |
17: 46,499,014 (GRCm39) |
Q234* |
probably null |
Het |
| Prkce |
T |
A |
17: 86,803,463 (GRCm39) |
M454K |
possibly damaging |
Het |
| Proser1 |
C |
A |
3: 53,385,366 (GRCm39) |
T416K |
probably benign |
Het |
| Prr14l |
G |
T |
5: 32,989,172 (GRCm39) |
|
probably benign |
Het |
| Rabgap1l |
A |
T |
1: 160,566,527 (GRCm39) |
D90E |
probably benign |
Het |
| Rp1l1 |
T |
A |
14: 64,266,415 (GRCm39) |
V667D |
possibly damaging |
Het |
| Rpp40 |
A |
T |
13: 36,082,604 (GRCm39) |
C256* |
probably null |
Het |
| Rps6ka5 |
A |
G |
12: 100,644,797 (GRCm39) |
L51P |
probably damaging |
Het |
| Rtp2 |
C |
T |
16: 23,746,457 (GRCm39) |
C78Y |
probably damaging |
Het |
| Ryr3 |
A |
G |
2: 112,508,715 (GRCm39) |
|
probably benign |
Het |
| Slc10a6 |
A |
G |
5: 103,756,922 (GRCm39) |
Y281H |
probably benign |
Het |
| Slc6a21 |
T |
G |
7: 44,932,197 (GRCm39) |
|
probably null |
Het |
| Smo |
A |
G |
6: 29,757,313 (GRCm39) |
Y476C |
probably damaging |
Het |
| Tacr3 |
A |
T |
3: 134,560,621 (GRCm39) |
T187S |
probably damaging |
Het |
| Tas1r3 |
G |
A |
4: 155,944,927 (GRCm39) |
R765C |
probably damaging |
Het |
| Tasp1 |
T |
C |
2: 139,890,164 (GRCm39) |
K71E |
possibly damaging |
Het |
| Tg |
A |
G |
15: 66,566,743 (GRCm39) |
I1264V |
probably benign |
Het |
| Tmem41a |
T |
C |
16: 21,764,911 (GRCm39) |
|
probably null |
Het |
| Tmem63a |
A |
G |
1: 180,793,105 (GRCm39) |
N459D |
probably benign |
Het |
| Ube2k |
A |
G |
5: 65,752,269 (GRCm39) |
T151A |
probably damaging |
Het |
| Ubr1 |
T |
C |
2: 120,773,034 (GRCm39) |
E402G |
probably benign |
Het |
| Ulk4 |
T |
A |
9: 120,981,248 (GRCm39) |
I897F |
probably benign |
Het |
| Usp30 |
A |
G |
5: 114,249,224 (GRCm39) |
E176G |
probably damaging |
Het |
| Utp20 |
A |
G |
10: 88,649,917 (GRCm39) |
F431S |
probably damaging |
Het |
| Vmn1r206 |
T |
C |
13: 22,804,782 (GRCm39) |
S142G |
probably benign |
Het |
| Wdr17 |
C |
T |
8: 55,085,416 (GRCm39) |
V1236M |
probably damaging |
Het |
| Zbtb32 |
T |
C |
7: 30,290,918 (GRCm39) |
K126E |
possibly damaging |
Het |
| Zeb1 |
A |
T |
18: 5,767,681 (GRCm39) |
S731C |
possibly damaging |
Het |
|
| Other mutations in Lrriq1 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00988:Lrriq1
|
APN |
10 |
102,997,757 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL01523:Lrriq1
|
APN |
10 |
103,053,977 (GRCm39) |
nonsense |
probably null |
|
|
IGL01637:Lrriq1
|
APN |
10 |
103,051,489 (GRCm39) |
missense |
probably benign |
|
|
IGL02019:Lrriq1
|
APN |
10 |
103,014,661 (GRCm39) |
missense |
probably benign |
0.02 |
|
IGL02153:Lrriq1
|
APN |
10 |
103,006,340 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL02341:Lrriq1
|
APN |
10 |
103,060,802 (GRCm39) |
missense |
probably benign |
0.03 |
|
IGL02343:Lrriq1
|
APN |
10 |
103,070,024 (GRCm39) |
splice site |
probably benign |
|
|
IGL02408:Lrriq1
|
APN |
10 |
102,982,142 (GRCm39) |
missense |
probably benign |
0.17 |
|
IGL02431:Lrriq1
|
APN |
10 |
103,036,500 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02540:Lrriq1
|
APN |
10 |
103,050,880 (GRCm39) |
missense |
probably benign |
0.02 |
|
IGL02558:Lrriq1
|
APN |
10 |
102,982,144 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02613:Lrriq1
|
APN |
10 |
102,980,409 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL02642:Lrriq1
|
APN |
10 |
103,057,322 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
IGL03027:Lrriq1
|
APN |
10 |
103,063,057 (GRCm39) |
missense |
probably benign |
0.35 |
|
PIT4362001:Lrriq1
|
UTSW |
10 |
102,907,055 (GRCm39) |
missense |
probably benign |
0.26 |
|
R0050:Lrriq1
|
UTSW |
10 |
102,904,792 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0050:Lrriq1
|
UTSW |
10 |
102,904,792 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0068:Lrriq1
|
UTSW |
10 |
102,899,279 (GRCm39) |
missense |
probably benign |
0.02 |
|
R0068:Lrriq1
|
UTSW |
10 |
102,899,279 (GRCm39) |
missense |
probably benign |
0.02 |
|
R0124:Lrriq1
|
UTSW |
10 |
103,006,281 (GRCm39) |
critical splice donor site |
probably null |
|
|
R0244:Lrriq1
|
UTSW |
10 |
103,051,634 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R0323:Lrriq1
|
UTSW |
10 |
103,057,150 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R0515:Lrriq1
|
UTSW |
10 |
102,904,829 (GRCm39) |
splice site |
probably null |
|
|
R0522:Lrriq1
|
UTSW |
10 |
102,997,638 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0701:Lrriq1
|
UTSW |
10 |
103,069,905 (GRCm39) |
missense |
probably benign |
|
|
R1220:Lrriq1
|
UTSW |
10 |
102,906,990 (GRCm39) |
missense |
probably benign |
0.05 |
|
R1261:Lrriq1
|
UTSW |
10 |
103,069,998 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
R1262:Lrriq1
|
UTSW |
10 |
103,069,998 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
R1451:Lrriq1
|
UTSW |
10 |
103,038,376 (GRCm39) |
splice site |
probably benign |
|
|
R1642:Lrriq1
|
UTSW |
10 |
103,050,317 (GRCm39) |
missense |
probably benign |
0.13 |
|
R1643:Lrriq1
|
UTSW |
10 |
103,050,685 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1647:Lrriq1
|
UTSW |
10 |
103,006,509 (GRCm39) |
nonsense |
probably null |
|
|
R1830:Lrriq1
|
UTSW |
10 |
102,997,620 (GRCm39) |
missense |
probably benign |
|
|
R1843:Lrriq1
|
UTSW |
10 |
103,063,034 (GRCm39) |
splice site |
probably null |
|
|
R2128:Lrriq1
|
UTSW |
10 |
103,050,718 (GRCm39) |
missense |
probably benign |
0.01 |
|
R2199:Lrriq1
|
UTSW |
10 |
102,904,774 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2354:Lrriq1
|
UTSW |
10 |
103,025,848 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2495:Lrriq1
|
UTSW |
10 |
103,038,242 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R2897:Lrriq1
|
UTSW |
10 |
103,063,111 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R2898:Lrriq1
|
UTSW |
10 |
103,063,111 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R2922:Lrriq1
|
UTSW |
10 |
103,050,536 (GRCm39) |
missense |
probably benign |
0.00 |
|
R2939:Lrriq1
|
UTSW |
10 |
102,980,750 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R2965:Lrriq1
|
UTSW |
10 |
103,050,761 (GRCm39) |
missense |
probably benign |
0.07 |
|
R2966:Lrriq1
|
UTSW |
10 |
103,050,761 (GRCm39) |
missense |
probably benign |
0.07 |
|
R3081:Lrriq1
|
UTSW |
10 |
102,980,750 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R3115:Lrriq1
|
UTSW |
10 |
103,006,294 (GRCm39) |
missense |
probably benign |
0.00 |
|
R3745:Lrriq1
|
UTSW |
10 |
103,006,717 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R3813:Lrriq1
|
UTSW |
10 |
103,051,972 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3814:Lrriq1
|
UTSW |
10 |
103,051,972 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3885:Lrriq1
|
UTSW |
10 |
103,051,967 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R4378:Lrriq1
|
UTSW |
10 |
103,038,225 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4632:Lrriq1
|
UTSW |
10 |
103,057,288 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4633:Lrriq1
|
UTSW |
10 |
103,036,424 (GRCm39) |
nonsense |
probably null |
|
|
R4663:Lrriq1
|
UTSW |
10 |
102,899,273 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
R4702:Lrriq1
|
UTSW |
10 |
103,051,610 (GRCm39) |
missense |
possibly damaging |
0.65 |
|
R4793:Lrriq1
|
UTSW |
10 |
103,006,327 (GRCm39) |
missense |
probably benign |
0.25 |
|
R4801:Lrriq1
|
UTSW |
10 |
103,057,179 (GRCm39) |
missense |
probably benign |
0.02 |
|
R4802:Lrriq1
|
UTSW |
10 |
103,057,179 (GRCm39) |
missense |
probably benign |
0.02 |
|
R4815:Lrriq1
|
UTSW |
10 |
102,980,739 (GRCm39) |
missense |
probably benign |
0.10 |
|
R4872:Lrriq1
|
UTSW |
10 |
103,014,649 (GRCm39) |
missense |
possibly damaging |
0.56 |
|
R4877:Lrriq1
|
UTSW |
10 |
103,069,899 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
R4894:Lrriq1
|
UTSW |
10 |
102,997,613 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
R4990:Lrriq1
|
UTSW |
10 |
103,036,420 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4991:Lrriq1
|
UTSW |
10 |
103,036,420 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5011:Lrriq1
|
UTSW |
10 |
103,025,784 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5013:Lrriq1
|
UTSW |
10 |
103,025,784 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5122:Lrriq1
|
UTSW |
10 |
103,023,314 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5282:Lrriq1
|
UTSW |
10 |
103,051,206 (GRCm39) |
missense |
probably benign |
0.01 |
|
R5311:Lrriq1
|
UTSW |
10 |
103,050,448 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5567:Lrriq1
|
UTSW |
10 |
103,006,457 (GRCm39) |
missense |
possibly damaging |
0.56 |
|
R5643:Lrriq1
|
UTSW |
10 |
103,051,301 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5683:Lrriq1
|
UTSW |
10 |
103,009,236 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5916:Lrriq1
|
UTSW |
10 |
103,057,243 (GRCm39) |
nonsense |
probably null |
|
|
R6008:Lrriq1
|
UTSW |
10 |
103,006,325 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6022:Lrriq1
|
UTSW |
10 |
103,051,395 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R6224:Lrriq1
|
UTSW |
10 |
103,051,618 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6254:Lrriq1
|
UTSW |
10 |
103,051,312 (GRCm39) |
missense |
probably benign |
0.15 |
|
R6311:Lrriq1
|
UTSW |
10 |
103,009,254 (GRCm39) |
missense |
probably benign |
0.03 |
|
R6460:Lrriq1
|
UTSW |
10 |
103,036,559 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6502:Lrriq1
|
UTSW |
10 |
103,063,045 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6637:Lrriq1
|
UTSW |
10 |
103,057,293 (GRCm39) |
missense |
probably benign |
0.06 |
|
R6719:Lrriq1
|
UTSW |
10 |
102,906,977 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6736:Lrriq1
|
UTSW |
10 |
103,017,750 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R6928:Lrriq1
|
UTSW |
10 |
103,050,800 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R6991:Lrriq1
|
UTSW |
10 |
103,023,319 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7174:Lrriq1
|
UTSW |
10 |
103,060,826 (GRCm39) |
missense |
probably benign |
|
|
R7241:Lrriq1
|
UTSW |
10 |
103,051,834 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7248:Lrriq1
|
UTSW |
10 |
103,059,611 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R7287:Lrriq1
|
UTSW |
10 |
103,051,877 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7402:Lrriq1
|
UTSW |
10 |
103,057,185 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
R7439:Lrriq1
|
UTSW |
10 |
103,050,380 (GRCm39) |
missense |
probably benign |
0.21 |
|
R7585:Lrriq1
|
UTSW |
10 |
103,050,807 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R7611:Lrriq1
|
UTSW |
10 |
103,036,432 (GRCm39) |
missense |
possibly damaging |
0.54 |
|
R7634:Lrriq1
|
UTSW |
10 |
103,036,462 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7767:Lrriq1
|
UTSW |
10 |
103,051,815 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7809:Lrriq1
|
UTSW |
10 |
103,051,678 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7910:Lrriq1
|
UTSW |
10 |
103,051,055 (GRCm39) |
nonsense |
probably null |
|
|
R8131:Lrriq1
|
UTSW |
10 |
103,051,572 (GRCm39) |
missense |
possibly damaging |
0.57 |
|
R8156:Lrriq1
|
UTSW |
10 |
102,992,196 (GRCm39) |
critical splice donor site |
probably null |
|
|
R8211:Lrriq1
|
UTSW |
10 |
103,006,408 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8304:Lrriq1
|
UTSW |
10 |
103,069,929 (GRCm39) |
missense |
possibly damaging |
0.57 |
|
R8487:Lrriq1
|
UTSW |
10 |
103,050,914 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R8500:Lrriq1
|
UTSW |
10 |
102,882,016 (GRCm39) |
missense |
|
|
|
R9013:Lrriq1
|
UTSW |
10 |
103,050,931 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9099:Lrriq1
|
UTSW |
10 |
103,051,864 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R9155:Lrriq1
|
UTSW |
10 |
103,050,640 (GRCm39) |
missense |
probably benign |
0.03 |
|
R9320:Lrriq1
|
UTSW |
10 |
103,057,144 (GRCm39) |
missense |
probably benign |
|
|
R9384:Lrriq1
|
UTSW |
10 |
103,006,458 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9469:Lrriq1
|
UTSW |
10 |
103,050,761 (GRCm39) |
missense |
probably benign |
0.07 |
|
R9585:Lrriq1
|
UTSW |
10 |
103,051,250 (GRCm39) |
missense |
probably benign |
|
|
R9706:Lrriq1
|
UTSW |
10 |
102,881,902 (GRCm39) |
missense |
|
|
|
R9780:Lrriq1
|
UTSW |
10 |
103,025,824 (GRCm39) |
missense |
probably damaging |
1.00 |
|
X0026:Lrriq1
|
UTSW |
10 |
103,051,565 (GRCm39) |
nonsense |
probably null |
|
|
Z1088:Lrriq1
|
UTSW |
10 |
103,038,307 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1176:Lrriq1
|
UTSW |
10 |
103,069,946 (GRCm39) |
missense |
probably damaging |
0.99 |
|
Z1176:Lrriq1
|
UTSW |
10 |
103,038,221 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1176:Lrriq1
|
UTSW |
10 |
103,038,220 (GRCm39) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- GCTCAAAGATTTCAGCCCAGG -3'
(R):5'- TTTCCATGCAGAAAAGCCTACC -3'
Sequencing Primer
(F):5'- GATTTCAGCCCAGGGTTTAAATG -3'
(R):5'- TGCAGAAAAGCCTACCATCACTG -3'
|
| Posted On |
2014-09-17 |
Incidental Mutation