Incidental Mutation 'R2130:A2ml1'
| ID |
227948 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
A2ml1
|
| Ensembl Gene |
ENSMUSG00000047228 |
| Gene Name |
alpha-2-macroglobulin like 1 |
| Synonyms |
BC048546, Ovos2 |
| MMRRC Submission |
040133-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R2130 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
|
| Chromosome |
6 |
| Chromosomal Location |
128516784-128558571 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to A
at 128553223 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Asparagine to Isoleucine
at position 178
(N178I)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000059426
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000060574]
|
| AlphaFold |
Q3UU35 |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000060574
AA Change: N178I
PolyPhen 2
Score 0.996 (Sensitivity: 0.55; Specificity: 0.98)
|
| SMART Domains |
Protein: ENSMUSP00000059426
Gene: ENSMUSG00000047228
AA Change: N178I
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
42 |
58 |
N/A |
INTRINSIC |
|
Pfam:A2M_N
|
120 |
213 |
6.3e-17 |
PFAM |
|
A2M_N_2
|
448 |
594 |
2.95e-37 |
SMART |
|
A2M
|
736 |
826 |
2.11e-33 |
SMART |
|
Pfam:Thiol-ester_cl
|
959 |
988 |
3.1e-17 |
PFAM |
|
Pfam:A2M_comp
|
1008 |
1255 |
2.3e-71 |
PFAM |
|
A2M_recep
|
1361 |
1447 |
1.22e-29 |
SMART |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000203129
|
| Meta Mutation Damage Score |
0.6467 |
| Coding Region Coverage |
- 1x: 99.2%
- 3x: 98.7%
- 10x: 97.5%
- 20x: 95.9%
|
| Validation Efficiency |
94% (94/100) |
| Allele List at MGI |
All alleles(2) : Gene trapped(2)
|
| Other mutations in this stock |
Total: 97 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Aadacl2fm3 |
T |
C |
3: 59,772,769 (GRCm39) |
V91A |
probably damaging |
Het |
| Adgrl2 |
T |
C |
3: 148,596,124 (GRCm39) |
I71V |
probably damaging |
Het |
| Adgrv1 |
T |
C |
13: 81,729,846 (GRCm39) |
T212A |
possibly damaging |
Het |
| Aopep |
T |
A |
13: 63,357,963 (GRCm39) |
C656S |
probably benign |
Het |
| Aox3 |
A |
G |
1: 58,209,002 (GRCm39) |
H845R |
probably damaging |
Het |
| Apaf1 |
A |
T |
10: 90,896,027 (GRCm39) |
Y348* |
probably null |
Het |
| Apobr |
A |
G |
7: 126,186,378 (GRCm39) |
T630A |
probably benign |
Het |
| Arhgap23 |
A |
G |
11: 97,342,387 (GRCm39) |
D223G |
possibly damaging |
Het |
| Asic1 |
A |
T |
15: 99,569,756 (GRCm39) |
T26S |
possibly damaging |
Het |
| Atp13a2 |
T |
A |
4: 140,732,327 (GRCm39) |
M864K |
probably damaging |
Het |
| Atrnl1 |
G |
A |
19: 57,643,426 (GRCm39) |
G438D |
probably damaging |
Het |
| Bbc3 |
T |
C |
7: 16,046,268 (GRCm39) |
V68A |
possibly damaging |
Het |
| Birc6 |
T |
C |
17: 74,966,149 (GRCm39) |
|
probably benign |
Het |
| Btnl9 |
A |
G |
11: 49,071,523 (GRCm39) |
F100S |
probably damaging |
Het |
| Castor2 |
G |
A |
5: 134,164,992 (GRCm39) |
C187Y |
probably damaging |
Het |
| Ccpg1 |
A |
G |
9: 72,920,440 (GRCm39) |
N685S |
probably damaging |
Het |
| Ces3b |
T |
A |
8: 105,819,607 (GRCm39) |
|
probably null |
Het |
| Cfhr2 |
T |
G |
1: 139,758,893 (GRCm39) |
R52S |
probably benign |
Het |
| Clhc1 |
A |
G |
11: 29,507,663 (GRCm39) |
I126V |
probably benign |
Het |
| Crocc |
T |
C |
4: 140,756,413 (GRCm39) |
I1071V |
probably benign |
Het |
| Dbt |
T |
A |
3: 116,332,773 (GRCm39) |
D16E |
probably damaging |
Het |
| Dnajc8 |
T |
C |
4: 132,271,370 (GRCm39) |
S62P |
possibly damaging |
Het |
| Dpyd |
T |
C |
3: 118,468,217 (GRCm39) |
V77A |
probably benign |
Het |
| Dram2 |
T |
A |
3: 106,478,076 (GRCm39) |
M136K |
possibly damaging |
Het |
| Dtx2 |
T |
A |
5: 136,040,894 (GRCm39) |
F100I |
probably damaging |
Het |
| Dync2h1 |
A |
T |
9: 7,011,253 (GRCm39) |
W3654R |
probably damaging |
Het |
| Fbxw10 |
T |
A |
11: 62,750,683 (GRCm39) |
I422N |
probably damaging |
Het |
| Fgf17 |
T |
C |
14: 70,875,927 (GRCm39) |
R102G |
probably damaging |
Het |
| Gm28040 |
AGTG |
AGTGGCACCTTTGGTG |
1: 133,255,059 (GRCm39) |
|
probably benign |
Het |
| Gm6578 |
C |
A |
6: 12,100,186 (GRCm39) |
|
noncoding transcript |
Het |
| Gm8374 |
T |
C |
14: 18,537,078 (GRCm39) |
T49A |
probably damaging |
Het |
| Gm9797 |
G |
T |
10: 11,485,113 (GRCm39) |
|
noncoding transcript |
Het |
| Golga3 |
T |
C |
5: 110,350,805 (GRCm39) |
|
probably null |
Het |
| Golim4 |
A |
T |
3: 75,815,456 (GRCm39) |
V116D |
probably damaging |
Het |
| Igfn1 |
AGGG |
AGG |
1: 135,902,590 (GRCm39) |
|
probably benign |
Het |
| Insrr |
G |
A |
3: 87,717,879 (GRCm39) |
|
probably null |
Het |
| Ipo9 |
ATCCTCCTCCTCCTCCTC |
ATCCTCCTCCTCCTCCTCCTC |
1: 135,314,006 (GRCm39) |
|
probably benign |
Het |
| Ipo9 |
A |
G |
1: 135,329,988 (GRCm39) |
V484A |
probably benign |
Het |
| Isoc2b |
A |
T |
7: 4,854,438 (GRCm39) |
I31N |
probably damaging |
Het |
| Kif5c |
T |
A |
2: 49,648,817 (GRCm39) |
|
probably benign |
Het |
| Krtap16-1 |
A |
T |
11: 99,876,602 (GRCm39) |
C267* |
probably null |
Het |
| Lamc2 |
T |
A |
1: 153,002,870 (GRCm39) |
D1037V |
probably damaging |
Het |
| Lhfpl2 |
A |
G |
13: 94,328,557 (GRCm39) |
D206G |
possibly damaging |
Het |
| Lmtk2 |
C |
T |
5: 144,111,806 (GRCm39) |
T842I |
possibly damaging |
Het |
| Mgat2 |
T |
C |
12: 69,232,068 (GRCm39) |
F214S |
probably damaging |
Het |
| Mki67 |
T |
A |
7: 135,305,970 (GRCm39) |
|
probably null |
Het |
| Mpo |
A |
G |
11: 87,688,187 (GRCm39) |
D282G |
possibly damaging |
Het |
| Myh10 |
A |
G |
11: 68,698,115 (GRCm39) |
|
probably benign |
Het |
| Myo15b |
G |
A |
11: 115,762,469 (GRCm39) |
V1229I |
probably benign |
Het |
| Nfatc2ip |
A |
G |
7: 125,989,634 (GRCm39) |
V250A |
probably benign |
Het |
| Niban2 |
A |
G |
2: 32,813,659 (GRCm39) |
K624R |
probably benign |
Het |
| Nrp1 |
A |
T |
8: 129,224,997 (GRCm39) |
E782D |
probably damaging |
Het |
| Olfml3 |
T |
A |
3: 103,643,185 (GRCm39) |
M399L |
probably benign |
Het |
| Optc |
A |
T |
1: 133,831,534 (GRCm39) |
|
probably null |
Het |
| Or1j13 |
A |
G |
2: 36,370,059 (GRCm39) |
S28P |
possibly damaging |
Het |
| Or2f1 |
C |
A |
6: 42,721,069 (GRCm39) |
L33M |
possibly damaging |
Het |
| Or56a5 |
T |
A |
7: 104,792,757 (GRCm39) |
I254F |
probably benign |
Het |
| Plekha6 |
C |
A |
1: 133,207,103 (GRCm39) |
|
probably null |
Het |
| Prelp |
C |
T |
1: 133,842,869 (GRCm39) |
R92K |
probably benign |
Het |
| Psph |
T |
A |
5: 129,864,603 (GRCm39) |
|
probably null |
Het |
| Ptpro |
A |
G |
6: 137,388,114 (GRCm39) |
|
probably null |
Het |
| Pzp |
T |
C |
6: 128,468,124 (GRCm39) |
|
probably null |
Het |
| Qrich2 |
C |
T |
11: 116,339,243 (GRCm39) |
|
probably benign |
Het |
| Ren1 |
C |
G |
1: 133,278,516 (GRCm39) |
|
probably null |
Het |
| Rfwd3 |
A |
T |
8: 112,024,034 (GRCm39) |
V96E |
probably benign |
Het |
| Rnf17 |
T |
C |
14: 56,730,811 (GRCm39) |
V1205A |
probably damaging |
Het |
| Ro60 |
T |
C |
1: 143,635,772 (GRCm39) |
D458G |
probably benign |
Het |
| Senp1 |
T |
A |
15: 97,973,848 (GRCm39) |
T132S |
probably benign |
Het |
| Sgo2b |
T |
C |
8: 64,380,181 (GRCm39) |
R884G |
probably benign |
Het |
| Slc10a5 |
G |
T |
3: 10,400,278 (GRCm39) |
D127E |
probably benign |
Het |
| Slc25a35 |
T |
G |
11: 68,859,791 (GRCm39) |
S101R |
possibly damaging |
Het |
| Slc6a13 |
T |
C |
6: 121,302,000 (GRCm39) |
L194P |
possibly damaging |
Het |
| Snw1 |
T |
G |
12: 87,499,473 (GRCm39) |
|
probably benign |
Het |
| Sort1 |
T |
A |
3: 108,259,002 (GRCm39) |
F678Y |
probably benign |
Het |
| Srsf12 |
C |
T |
4: 33,225,764 (GRCm39) |
|
probably benign |
Het |
| Ssxa1 |
T |
A |
X: 20,985,581 (GRCm39) |
|
probably benign |
Het |
| Stard13 |
T |
C |
5: 150,968,633 (GRCm39) |
Y879C |
probably damaging |
Het |
| Syt2 |
ACTCTCTCT |
ACTCTCTCTCT |
1: 134,674,479 (GRCm39) |
|
probably benign |
Het |
| Tacr3 |
T |
C |
3: 134,637,941 (GRCm39) |
V366A |
probably benign |
Het |
| Tasor |
T |
A |
14: 27,168,345 (GRCm39) |
Y296N |
probably damaging |
Het |
| Tasor |
A |
G |
14: 27,198,571 (GRCm39) |
N1301S |
possibly damaging |
Het |
| Tecpr1 |
T |
A |
5: 144,145,463 (GRCm39) |
T595S |
probably benign |
Het |
| Tjp3 |
T |
A |
10: 81,113,888 (GRCm39) |
M457L |
possibly damaging |
Het |
| Tkfc |
A |
G |
19: 10,573,405 (GRCm39) |
I279T |
probably damaging |
Het |
| Tmem98 |
A |
G |
11: 80,708,348 (GRCm39) |
E106G |
probably damaging |
Het |
| Tnnt2 |
TG |
TGG |
1: 135,774,499 (GRCm39) |
|
probably benign |
Het |
| Trim41 |
C |
A |
11: 48,698,419 (GRCm39) |
G516W |
probably damaging |
Het |
| Ttn |
T |
C |
2: 76,572,861 (GRCm39) |
T24265A |
possibly damaging |
Het |
| Usp37 |
A |
G |
1: 74,500,815 (GRCm39) |
V582A |
probably damaging |
Het |
| Vps13b |
T |
A |
15: 35,671,546 (GRCm39) |
I1683N |
probably benign |
Het |
| Vps13d |
C |
T |
4: 144,882,671 (GRCm39) |
R968H |
probably benign |
Het |
| Vps35l |
T |
C |
7: 118,393,798 (GRCm39) |
Y516H |
probably damaging |
Het |
| Vwf |
C |
T |
6: 125,634,020 (GRCm39) |
T166I |
probably damaging |
Het |
| Zfp280d |
T |
C |
9: 72,215,287 (GRCm39) |
F133L |
probably damaging |
Het |
| Zfp459 |
A |
T |
13: 67,556,395 (GRCm39) |
H229Q |
probably benign |
Het |
| Zfyve26 |
T |
A |
12: 79,315,208 (GRCm39) |
I1423F |
possibly damaging |
Het |
| Zmynd19 |
T |
A |
2: 24,842,648 (GRCm39) |
Y15* |
probably null |
Het |
|
| Other mutations in A2ml1 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00513:A2ml1
|
APN |
6 |
128,555,119 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
IGL00596:A2ml1
|
APN |
6 |
128,547,030 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL00912:A2ml1
|
APN |
6 |
128,529,270 (GRCm39) |
missense |
probably benign |
0.04 |
|
IGL01320:A2ml1
|
APN |
6 |
128,552,551 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL01470:A2ml1
|
APN |
6 |
128,557,375 (GRCm39) |
missense |
probably damaging |
0.96 |
|
IGL01576:A2ml1
|
APN |
6 |
128,531,293 (GRCm39) |
splice site |
probably benign |
|
|
IGL01761:A2ml1
|
APN |
6 |
128,523,300 (GRCm39) |
missense |
possibly damaging |
0.61 |
|
IGL01792:A2ml1
|
APN |
6 |
128,537,642 (GRCm39) |
missense |
probably benign |
0.04 |
|
IGL01843:A2ml1
|
APN |
6 |
128,530,301 (GRCm39) |
splice site |
probably benign |
|
|
IGL01946:A2ml1
|
APN |
6 |
128,547,442 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
IGL02016:A2ml1
|
APN |
6 |
128,535,298 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02170:A2ml1
|
APN |
6 |
128,524,173 (GRCm39) |
missense |
possibly damaging |
0.58 |
|
IGL02269:A2ml1
|
APN |
6 |
128,530,301 (GRCm39) |
splice site |
probably benign |
|
|
IGL02589:A2ml1
|
APN |
6 |
128,558,463 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL02959:A2ml1
|
APN |
6 |
128,544,023 (GRCm39) |
missense |
probably benign |
0.04 |
|
IGL02970:A2ml1
|
APN |
6 |
128,546,942 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03206:A2ml1
|
APN |
6 |
128,530,239 (GRCm39) |
missense |
possibly damaging |
0.50 |
|
IGL03298:A2ml1
|
APN |
6 |
128,520,923 (GRCm39) |
missense |
probably benign |
0.00 |
|
1mM(1):A2ml1
|
UTSW |
6 |
128,557,923 (GRCm39) |
missense |
probably benign |
0.02 |
|
R0055:A2ml1
|
UTSW |
6 |
128,547,057 (GRCm39) |
splice site |
probably benign |
|
|
R0055:A2ml1
|
UTSW |
6 |
128,547,057 (GRCm39) |
splice site |
probably benign |
|
|
R0069:A2ml1
|
UTSW |
6 |
128,538,525 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0069:A2ml1
|
UTSW |
6 |
128,538,525 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0128:A2ml1
|
UTSW |
6 |
128,552,602 (GRCm39) |
splice site |
probably benign |
|
|
R0299:A2ml1
|
UTSW |
6 |
128,530,195 (GRCm39) |
splice site |
probably benign |
|
|
R0523:A2ml1
|
UTSW |
6 |
128,535,289 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R0565:A2ml1
|
UTSW |
6 |
128,545,706 (GRCm39) |
nonsense |
probably null |
|
|
R0599:A2ml1
|
UTSW |
6 |
128,529,208 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0626:A2ml1
|
UTSW |
6 |
128,527,736 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0732:A2ml1
|
UTSW |
6 |
128,523,411 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0880:A2ml1
|
UTSW |
6 |
128,537,609 (GRCm39) |
missense |
possibly damaging |
0.49 |
|
R1070:A2ml1
|
UTSW |
6 |
128,520,263 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1166:A2ml1
|
UTSW |
6 |
128,547,880 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1278:A2ml1
|
UTSW |
6 |
128,535,470 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1421:A2ml1
|
UTSW |
6 |
128,520,923 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1536:A2ml1
|
UTSW |
6 |
128,524,196 (GRCm39) |
nonsense |
probably null |
|
|
R1786:A2ml1
|
UTSW |
6 |
128,553,223 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1808:A2ml1
|
UTSW |
6 |
128,520,262 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1813:A2ml1
|
UTSW |
6 |
128,543,236 (GRCm39) |
missense |
probably benign |
0.34 |
|
R1863:A2ml1
|
UTSW |
6 |
128,527,746 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R2007:A2ml1
|
UTSW |
6 |
128,519,855 (GRCm39) |
missense |
probably benign |
0.13 |
|
R2062:A2ml1
|
UTSW |
6 |
128,529,271 (GRCm39) |
missense |
probably benign |
0.08 |
|
R2127:A2ml1
|
UTSW |
6 |
128,535,400 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2131:A2ml1
|
UTSW |
6 |
128,553,223 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2201:A2ml1
|
UTSW |
6 |
128,524,268 (GRCm39) |
missense |
probably null |
0.34 |
|
R2319:A2ml1
|
UTSW |
6 |
128,557,349 (GRCm39) |
missense |
probably benign |
0.01 |
|
R2321:A2ml1
|
UTSW |
6 |
128,557,349 (GRCm39) |
missense |
probably benign |
0.01 |
|
R2322:A2ml1
|
UTSW |
6 |
128,557,349 (GRCm39) |
missense |
probably benign |
0.01 |
|
R2369:A2ml1
|
UTSW |
6 |
128,557,349 (GRCm39) |
missense |
probably benign |
0.01 |
|
R2370:A2ml1
|
UTSW |
6 |
128,557,349 (GRCm39) |
missense |
probably benign |
0.01 |
|
R2371:A2ml1
|
UTSW |
6 |
128,557,349 (GRCm39) |
missense |
probably benign |
0.01 |
|
R2372:A2ml1
|
UTSW |
6 |
128,557,349 (GRCm39) |
missense |
probably benign |
0.01 |
|
R2375:A2ml1
|
UTSW |
6 |
128,557,349 (GRCm39) |
missense |
probably benign |
0.01 |
|
R2893:A2ml1
|
UTSW |
6 |
128,557,349 (GRCm39) |
missense |
probably benign |
0.01 |
|
R2894:A2ml1
|
UTSW |
6 |
128,557,349 (GRCm39) |
missense |
probably benign |
0.01 |
|
R3438:A2ml1
|
UTSW |
6 |
128,557,349 (GRCm39) |
missense |
probably benign |
0.01 |
|
R3615:A2ml1
|
UTSW |
6 |
128,535,257 (GRCm39) |
missense |
probably benign |
0.07 |
|
R3616:A2ml1
|
UTSW |
6 |
128,535,257 (GRCm39) |
missense |
probably benign |
0.07 |
|
R3773:A2ml1
|
UTSW |
6 |
128,532,046 (GRCm39) |
missense |
probably benign |
0.02 |
|
R3785:A2ml1
|
UTSW |
6 |
128,521,887 (GRCm39) |
critical splice donor site |
probably null |
|
|
R3803:A2ml1
|
UTSW |
6 |
128,522,033 (GRCm39) |
missense |
probably benign |
0.17 |
|
R3824:A2ml1
|
UTSW |
6 |
128,545,726 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R3878:A2ml1
|
UTSW |
6 |
128,531,324 (GRCm39) |
missense |
probably benign |
0.05 |
|
R4176:A2ml1
|
UTSW |
6 |
128,522,000 (GRCm39) |
missense |
possibly damaging |
0.68 |
|
R4229:A2ml1
|
UTSW |
6 |
128,557,349 (GRCm39) |
missense |
probably benign |
0.01 |
|
R4230:A2ml1
|
UTSW |
6 |
128,557,349 (GRCm39) |
missense |
probably benign |
0.01 |
|
R4348:A2ml1
|
UTSW |
6 |
128,557,349 (GRCm39) |
missense |
probably benign |
0.01 |
|
R4351:A2ml1
|
UTSW |
6 |
128,557,349 (GRCm39) |
missense |
probably benign |
0.01 |
|
R4352:A2ml1
|
UTSW |
6 |
128,557,349 (GRCm39) |
missense |
probably benign |
0.01 |
|
R4353:A2ml1
|
UTSW |
6 |
128,557,349 (GRCm39) |
missense |
probably benign |
0.01 |
|
R4427:A2ml1
|
UTSW |
6 |
128,522,009 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4971:A2ml1
|
UTSW |
6 |
128,524,190 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R5014:A2ml1
|
UTSW |
6 |
128,520,896 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5369:A2ml1
|
UTSW |
6 |
128,545,796 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R5532:A2ml1
|
UTSW |
6 |
128,530,293 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R5860:A2ml1
|
UTSW |
6 |
128,518,024 (GRCm39) |
missense |
probably benign |
0.15 |
|
R5872:A2ml1
|
UTSW |
6 |
128,538,489 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5926:A2ml1
|
UTSW |
6 |
128,537,608 (GRCm39) |
missense |
probably benign |
|
|
R5977:A2ml1
|
UTSW |
6 |
128,558,085 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5980:A2ml1
|
UTSW |
6 |
128,544,018 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
R6014:A2ml1
|
UTSW |
6 |
128,548,948 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6032:A2ml1
|
UTSW |
6 |
128,526,799 (GRCm39) |
nonsense |
probably null |
|
|
R6032:A2ml1
|
UTSW |
6 |
128,526,799 (GRCm39) |
nonsense |
probably null |
|
|
R6061:A2ml1
|
UTSW |
6 |
128,545,675 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6327:A2ml1
|
UTSW |
6 |
128,535,655 (GRCm39) |
splice site |
probably null |
|
|
R6331:A2ml1
|
UTSW |
6 |
128,529,199 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R6465:A2ml1
|
UTSW |
6 |
128,518,041 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6640:A2ml1
|
UTSW |
6 |
128,530,248 (GRCm39) |
missense |
probably benign |
0.41 |
|
R6792:A2ml1
|
UTSW |
6 |
128,523,292 (GRCm39) |
nonsense |
probably null |
|
|
R6793:A2ml1
|
UTSW |
6 |
128,523,292 (GRCm39) |
nonsense |
probably null |
|
|
R7207:A2ml1
|
UTSW |
6 |
128,527,734 (GRCm39) |
missense |
probably benign |
0.04 |
|
R7378:A2ml1
|
UTSW |
6 |
128,523,210 (GRCm39) |
critical splice donor site |
probably null |
|
|
R7556:A2ml1
|
UTSW |
6 |
128,546,927 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8010:A2ml1
|
UTSW |
6 |
128,557,303 (GRCm39) |
missense |
probably benign |
0.08 |
|
R8017:A2ml1
|
UTSW |
6 |
128,558,410 (GRCm39) |
critical splice donor site |
probably null |
|
|
R8019:A2ml1
|
UTSW |
6 |
128,558,410 (GRCm39) |
critical splice donor site |
probably null |
|
|
R8035:A2ml1
|
UTSW |
6 |
128,530,243 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8094:A2ml1
|
UTSW |
6 |
128,549,045 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8144:A2ml1
|
UTSW |
6 |
128,546,962 (GRCm39) |
missense |
possibly damaging |
0.84 |
|
R8365:A2ml1
|
UTSW |
6 |
128,557,918 (GRCm39) |
nonsense |
probably null |
|
|
R8382:A2ml1
|
UTSW |
6 |
128,537,645 (GRCm39) |
missense |
probably benign |
0.01 |
|
R8388:A2ml1
|
UTSW |
6 |
128,548,937 (GRCm39) |
missense |
probably benign |
0.03 |
|
R8717:A2ml1
|
UTSW |
6 |
128,543,958 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8947:A2ml1
|
UTSW |
6 |
128,529,219 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8970:A2ml1
|
UTSW |
6 |
128,545,726 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9025:A2ml1
|
UTSW |
6 |
128,534,545 (GRCm39) |
missense |
possibly damaging |
0.49 |
|
R9083:A2ml1
|
UTSW |
6 |
128,534,524 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R9129:A2ml1
|
UTSW |
6 |
128,523,223 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9145:A2ml1
|
UTSW |
6 |
128,536,032 (GRCm39) |
missense |
probably benign |
|
|
R9165:A2ml1
|
UTSW |
6 |
128,537,632 (GRCm39) |
missense |
probably benign |
|
|
R9285:A2ml1
|
UTSW |
6 |
128,526,756 (GRCm39) |
missense |
probably benign |
|
|
R9408:A2ml1
|
UTSW |
6 |
128,522,030 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R9486:A2ml1
|
UTSW |
6 |
128,546,942 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9781:A2ml1
|
UTSW |
6 |
128,519,860 (GRCm39) |
missense |
probably benign |
0.01 |
|
RF014:A2ml1
|
UTSW |
6 |
128,547,031 (GRCm39) |
missense |
probably damaging |
0.96 |
|
X0063:A2ml1
|
UTSW |
6 |
128,548,975 (GRCm39) |
missense |
probably benign |
|
|
Z1176:A2ml1
|
UTSW |
6 |
128,548,940 (GRCm39) |
missense |
probably benign |
0.09 |
|
Z1177:A2ml1
|
UTSW |
6 |
128,552,570 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
Z1177:A2ml1
|
UTSW |
6 |
128,538,579 (GRCm39) |
nonsense |
probably null |
|
|
Z1177:A2ml1
|
UTSW |
6 |
128,522,039 (GRCm39) |
missense |
probably benign |
|
|
| Predicted Primers |
PCR Primer
(F):5'- AAACCATTGCGTTCTGTTGC -3'
(R):5'- TTGGGGAGCACTATTCTGGAC -3'
Sequencing Primer
(F):5'- CTTTGAACTTGTGTGTAGGAGAATC -3'
(R):5'- GGGAGCACTATTCTGGACTAATTATG -3'
|
| Posted On |
2014-09-17 |
Incidental Mutation