Incidental Mutation 'R0153:Arid1b'
| ID |
22872 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Arid1b
|
| Ensembl Gene |
ENSMUSG00000069729 |
| Gene Name |
AT-rich interaction domain 1B |
| Synonyms |
9330189K18Rik, B230217J03Rik |
| MMRRC Submission |
038436-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably essential
(E-score: 0.813)
|
| Stock # |
R0153 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
(trace)
|
| Chromosome |
17 |
| Chromosomal Location |
5044607-5397931 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
G to A
at 5393207 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Alanine to Threonine
at position 2246
(A2246T)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000156119
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000092723]
[ENSMUST00000115797]
[ENSMUST00000115799]
[ENSMUST00000232180]
|
| AlphaFold |
E9Q4N7 |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000092723
AA Change: A2193T
PolyPhen 2
Score 0.999 (Sensitivity: 0.14; Specificity: 0.99)
|
| SMART Domains |
Protein: ENSMUSP00000090398
Gene: ENSMUSG00000069729
AA Change: A2193T
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
2 |
51 |
N/A |
INTRINSIC |
|
low complexity region
|
69 |
132 |
N/A |
INTRINSIC |
|
low complexity region
|
139 |
150 |
N/A |
INTRINSIC |
|
low complexity region
|
201 |
224 |
N/A |
INTRINSIC |
|
low complexity region
|
232 |
247 |
N/A |
INTRINSIC |
|
low complexity region
|
257 |
276 |
N/A |
INTRINSIC |
|
low complexity region
|
301 |
371 |
N/A |
INTRINSIC |
|
low complexity region
|
379 |
407 |
N/A |
INTRINSIC |
|
low complexity region
|
438 |
476 |
N/A |
INTRINSIC |
|
low complexity region
|
485 |
499 |
N/A |
INTRINSIC |
|
low complexity region
|
538 |
558 |
N/A |
INTRINSIC |
|
low complexity region
|
574 |
591 |
N/A |
INTRINSIC |
|
low complexity region
|
596 |
611 |
N/A |
INTRINSIC |
|
low complexity region
|
615 |
640 |
N/A |
INTRINSIC |
|
low complexity region
|
691 |
707 |
N/A |
INTRINSIC |
|
low complexity region
|
719 |
740 |
N/A |
INTRINSIC |
|
low complexity region
|
743 |
773 |
N/A |
INTRINSIC |
|
low complexity region
|
805 |
816 |
N/A |
INTRINSIC |
|
low complexity region
|
912 |
930 |
N/A |
INTRINSIC |
|
low complexity region
|
936 |
952 |
N/A |
INTRINSIC |
|
low complexity region
|
974 |
985 |
N/A |
INTRINSIC |
|
low complexity region
|
1036 |
1045 |
N/A |
INTRINSIC |
|
ARID
|
1057 |
1147 |
9.9e-33 |
SMART |
|
BRIGHT
|
1061 |
1152 |
7.62e-41 |
SMART |
|
low complexity region
|
1166 |
1177 |
N/A |
INTRINSIC |
|
low complexity region
|
1257 |
1268 |
N/A |
INTRINSIC |
|
low complexity region
|
1336 |
1364 |
N/A |
INTRINSIC |
|
low complexity region
|
1426 |
1456 |
N/A |
INTRINSIC |
|
low complexity region
|
1473 |
1486 |
N/A |
INTRINSIC |
|
low complexity region
|
1579 |
1595 |
N/A |
INTRINSIC |
|
coiled coil region
|
1724 |
1745 |
N/A |
INTRINSIC |
|
low complexity region
|
1835 |
1843 |
N/A |
INTRINSIC |
|
Pfam:DUF3518
|
1933 |
2189 |
1.5e-152 |
PFAM |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000115797
AA Change: A2194T
PolyPhen 2
Score 0.994 (Sensitivity: 0.69; Specificity: 0.97)
|
| SMART Domains |
Protein: ENSMUSP00000111463
Gene: ENSMUSG00000069729
AA Change: A2194T
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
17 |
80 |
N/A |
INTRINSIC |
|
low complexity region
|
87 |
98 |
N/A |
INTRINSIC |
|
low complexity region
|
149 |
172 |
N/A |
INTRINSIC |
|
low complexity region
|
180 |
195 |
N/A |
INTRINSIC |
|
low complexity region
|
205 |
224 |
N/A |
INTRINSIC |
|
low complexity region
|
249 |
319 |
N/A |
INTRINSIC |
|
low complexity region
|
327 |
355 |
N/A |
INTRINSIC |
|
low complexity region
|
386 |
424 |
N/A |
INTRINSIC |
|
low complexity region
|
433 |
447 |
N/A |
INTRINSIC |
|
low complexity region
|
486 |
506 |
N/A |
INTRINSIC |
|
low complexity region
|
522 |
539 |
N/A |
INTRINSIC |
|
low complexity region
|
544 |
559 |
N/A |
INTRINSIC |
|
low complexity region
|
563 |
588 |
N/A |
INTRINSIC |
|
low complexity region
|
639 |
655 |
N/A |
INTRINSIC |
|
low complexity region
|
667 |
688 |
N/A |
INTRINSIC |
|
low complexity region
|
691 |
721 |
N/A |
INTRINSIC |
|
low complexity region
|
753 |
764 |
N/A |
INTRINSIC |
|
low complexity region
|
860 |
878 |
N/A |
INTRINSIC |
|
low complexity region
|
884 |
900 |
N/A |
INTRINSIC |
|
low complexity region
|
922 |
933 |
N/A |
INTRINSIC |
|
Blast:ARID
|
981 |
1028 |
1e-8 |
BLAST |
|
low complexity region
|
1029 |
1054 |
N/A |
INTRINSIC |
|
ARID
|
1058 |
1148 |
9.9e-33 |
SMART |
|
BRIGHT
|
1062 |
1153 |
7.62e-41 |
SMART |
|
low complexity region
|
1167 |
1178 |
N/A |
INTRINSIC |
|
low complexity region
|
1258 |
1269 |
N/A |
INTRINSIC |
|
low complexity region
|
1337 |
1365 |
N/A |
INTRINSIC |
|
low complexity region
|
1427 |
1457 |
N/A |
INTRINSIC |
|
low complexity region
|
1474 |
1487 |
N/A |
INTRINSIC |
|
low complexity region
|
1580 |
1596 |
N/A |
INTRINSIC |
|
coiled coil region
|
1725 |
1746 |
N/A |
INTRINSIC |
|
low complexity region
|
1836 |
1844 |
N/A |
INTRINSIC |
|
Pfam:DUF3518
|
1935 |
2190 |
6.3e-121 |
PFAM |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000115799
AA Change: A1712T
PolyPhen 2
Score 0.997 (Sensitivity: 0.41; Specificity: 0.98)
|
| SMART Domains |
Protein: ENSMUSP00000111465
Gene: ENSMUSG00000069729
AA Change: A1712T
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
34 |
54 |
N/A |
INTRINSIC |
|
low complexity region
|
70 |
87 |
N/A |
INTRINSIC |
|
low complexity region
|
92 |
107 |
N/A |
INTRINSIC |
|
low complexity region
|
111 |
136 |
N/A |
INTRINSIC |
|
low complexity region
|
187 |
203 |
N/A |
INTRINSIC |
|
low complexity region
|
215 |
236 |
N/A |
INTRINSIC |
|
low complexity region
|
271 |
282 |
N/A |
INTRINSIC |
|
low complexity region
|
378 |
396 |
N/A |
INTRINSIC |
|
low complexity region
|
402 |
418 |
N/A |
INTRINSIC |
|
low complexity region
|
440 |
451 |
N/A |
INTRINSIC |
|
Blast:ARID
|
499 |
546 |
1e-8 |
BLAST |
|
low complexity region
|
547 |
572 |
N/A |
INTRINSIC |
|
ARID
|
576 |
666 |
9.9e-33 |
SMART |
|
BRIGHT
|
580 |
671 |
7.62e-41 |
SMART |
|
low complexity region
|
685 |
696 |
N/A |
INTRINSIC |
|
low complexity region
|
776 |
787 |
N/A |
INTRINSIC |
|
low complexity region
|
855 |
883 |
N/A |
INTRINSIC |
|
low complexity region
|
945 |
975 |
N/A |
INTRINSIC |
|
low complexity region
|
992 |
1005 |
N/A |
INTRINSIC |
|
low complexity region
|
1098 |
1114 |
N/A |
INTRINSIC |
|
coiled coil region
|
1243 |
1264 |
N/A |
INTRINSIC |
|
low complexity region
|
1354 |
1362 |
N/A |
INTRINSIC |
|
Pfam:DUF3518
|
1452 |
1708 |
1.1e-152 |
PFAM |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000232180
AA Change: A2246T
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| Meta Mutation Damage Score |
0.1349 |
| Coding Region Coverage |
- 1x: 98.9%
- 3x: 98.0%
- 10x: 95.5%
- 20x: 90.1%
|
| Validation Efficiency |
97% (99/102) |
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This locus encodes an AT-rich DNA interacting domain-containing protein. The encoded protein is a component of the SWI/SNF chromatin remodeling complex and may play a role in cell-cycle activation. The protein encoded by this locus is similar to AT-rich interactive domain-containing protein 1A. These two proteins function as alternative, mutually exclusive ARID-subunits of the SWI/SNF complex. The associated complexes play opposing roles. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2016]
|
| Allele List at MGI |
All alleles(61) : Targeted(2) Gene trapped(59)
|
| Other mutations in this stock |
Total: 85 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Abcb9 |
T |
C |
5: 124,218,119 (GRCm39) |
M406V |
probably benign |
Het |
| Adar |
T |
C |
3: 89,638,121 (GRCm39) |
S2P |
probably benign |
Het |
| Adgre1 |
T |
A |
17: 57,750,939 (GRCm39) |
S538T |
possibly damaging |
Het |
| Alms1 |
T |
A |
6: 85,618,363 (GRCm39) |
I2803N |
possibly damaging |
Het |
| Amn1 |
G |
T |
6: 149,090,091 (GRCm39) |
|
probably benign |
Het |
| BC024139 |
T |
C |
15: 76,005,947 (GRCm39) |
E418G |
probably damaging |
Het |
| Bok |
A |
G |
1: 93,614,239 (GRCm39) |
D24G |
probably damaging |
Het |
| Cabp2 |
T |
C |
19: 4,134,913 (GRCm39) |
|
probably benign |
Het |
| Ccdc141 |
C |
A |
2: 76,995,582 (GRCm39) |
|
probably benign |
Het |
| Ccdc178 |
T |
C |
18: 22,283,492 (GRCm39) |
T13A |
probably benign |
Het |
| Ccdc42 |
G |
T |
11: 68,478,476 (GRCm39) |
V33F |
possibly damaging |
Het |
| Clcn7 |
G |
A |
17: 25,368,176 (GRCm39) |
|
probably benign |
Het |
| Cluh |
A |
G |
11: 74,548,176 (GRCm39) |
|
probably benign |
Het |
| Cr1l |
A |
T |
1: 194,797,164 (GRCm39) |
|
probably benign |
Het |
| Cracdl |
A |
G |
1: 37,663,720 (GRCm39) |
V726A |
probably benign |
Het |
| Csnk1g3 |
T |
A |
18: 54,051,861 (GRCm39) |
|
probably benign |
Het |
| Depdc5 |
T |
C |
5: 33,091,281 (GRCm39) |
|
probably benign |
Het |
| Dgkh |
A |
C |
14: 78,807,569 (GRCm39) |
Y1149* |
probably null |
Het |
| Dipk2a |
G |
T |
9: 94,406,533 (GRCm39) |
D291E |
probably benign |
Het |
| Dnai1 |
A |
G |
4: 41,635,162 (GRCm39) |
|
probably benign |
Het |
| Dync2i1 |
A |
G |
12: 116,196,256 (GRCm39) |
V497A |
probably benign |
Het |
| Efcab2 |
A |
G |
1: 178,302,451 (GRCm39) |
E65G |
possibly damaging |
Het |
| Eif4a3l1 |
A |
T |
6: 136,305,842 (GRCm39) |
D101V |
probably damaging |
Het |
| Eno1b |
T |
C |
18: 48,180,806 (GRCm39) |
I328T |
probably benign |
Het |
| Fgfr4 |
A |
G |
13: 55,309,198 (GRCm39) |
|
probably benign |
Het |
| Garin5b |
A |
T |
7: 4,773,286 (GRCm39) |
L177Q |
probably damaging |
Het |
| Gm10720 |
A |
C |
9: 3,015,787 (GRCm39) |
S44R |
probably null |
Het |
| Gm17535 |
T |
A |
9: 3,035,786 (GRCm39) |
L218H |
probably benign |
Het |
| Gm6471 |
A |
T |
7: 142,385,368 (GRCm39) |
|
noncoding transcript |
Het |
| Hnrnpm |
C |
T |
17: 33,865,489 (GRCm39) |
R724Q |
probably damaging |
Het |
| Homer1 |
C |
T |
13: 93,528,254 (GRCm39) |
T117I |
possibly damaging |
Het |
| Hoxd4 |
A |
T |
2: 74,557,801 (GRCm39) |
Q60L |
probably damaging |
Het |
| Ift172 |
T |
C |
5: 31,417,968 (GRCm39) |
R1274G |
probably benign |
Het |
| Ino80d |
A |
G |
1: 63,097,477 (GRCm39) |
S806P |
probably damaging |
Het |
| Itga10 |
T |
C |
3: 96,561,016 (GRCm39) |
V627A |
probably benign |
Het |
| Itgb2l |
A |
G |
16: 96,238,569 (GRCm39) |
Y77H |
possibly damaging |
Het |
| Kel |
A |
T |
6: 41,678,877 (GRCm39) |
H195Q |
probably benign |
Het |
| Klhdc7a |
A |
G |
4: 139,694,582 (GRCm39) |
S122P |
possibly damaging |
Het |
| Krt71 |
T |
A |
15: 101,643,141 (GRCm39) |
I456F |
possibly damaging |
Het |
| Lats1 |
T |
A |
10: 7,567,339 (GRCm39) |
S37T |
probably damaging |
Het |
| Lrp1b |
T |
A |
2: 41,013,031 (GRCm39) |
H1858L |
possibly damaging |
Het |
| Matk |
A |
T |
10: 81,098,676 (GRCm39) |
T461S |
probably benign |
Het |
| Meikin |
A |
G |
11: 54,300,468 (GRCm39) |
|
probably benign |
Het |
| Muc6 |
T |
C |
7: 141,214,029 (GRCm39) |
Q2832R |
possibly damaging |
Het |
| Myo10 |
T |
C |
15: 25,781,324 (GRCm39) |
F194L |
possibly damaging |
Het |
| Nbas |
G |
A |
12: 13,323,877 (GRCm39) |
|
probably benign |
Het |
| Nme4 |
A |
G |
17: 26,312,831 (GRCm39) |
|
probably null |
Het |
| Or13p8 |
A |
T |
4: 118,583,530 (GRCm39) |
I29F |
possibly damaging |
Het |
| Or4c112 |
T |
A |
2: 88,853,540 (GRCm39) |
N269I |
probably benign |
Het |
| Or5w13 |
A |
G |
2: 87,523,948 (GRCm39) |
S93P |
probably benign |
Het |
| Or7g32 |
T |
A |
9: 19,408,233 (GRCm39) |
L63H |
probably damaging |
Het |
| Or8g34 |
T |
C |
9: 39,372,967 (GRCm39) |
V80A |
probably damaging |
Het |
| Pacsin2 |
T |
C |
15: 83,261,862 (GRCm39) |
Q473R |
probably benign |
Het |
| Patz1 |
A |
G |
11: 3,243,288 (GRCm39) |
H427R |
probably damaging |
Het |
| Pkp3 |
A |
G |
7: 140,663,256 (GRCm39) |
Y367C |
probably damaging |
Het |
| Prdm2 |
G |
A |
4: 142,860,338 (GRCm39) |
P984L |
possibly damaging |
Het |
| Rev3l |
T |
A |
10: 39,750,124 (GRCm39) |
C3091* |
probably null |
Het |
| Rims4 |
C |
T |
2: 163,705,849 (GRCm39) |
V262M |
possibly damaging |
Het |
| Rpl5 |
T |
C |
5: 108,052,623 (GRCm39) |
F140L |
probably benign |
Het |
| Sec24a |
A |
C |
11: 51,591,653 (GRCm39) |
I1014M |
probably benign |
Het |
| Serpinb11 |
A |
G |
1: 107,299,933 (GRCm39) |
H93R |
probably benign |
Het |
| Shank2 |
C |
A |
7: 143,623,872 (GRCm39) |
H286N |
probably benign |
Het |
| Sipa1l2 |
G |
T |
8: 126,148,637 (GRCm39) |
Q1651K |
probably damaging |
Het |
| Slc17a3 |
C |
T |
13: 24,039,841 (GRCm39) |
S293F |
probably damaging |
Het |
| Slc30a5 |
A |
T |
13: 100,963,002 (GRCm39) |
F75L |
possibly damaging |
Het |
| Slco1a1 |
G |
T |
6: 141,856,427 (GRCm39) |
|
probably benign |
Het |
| Smg5 |
C |
T |
3: 88,261,179 (GRCm39) |
|
probably benign |
Het |
| Snapc1 |
C |
T |
12: 74,021,806 (GRCm39) |
R81C |
probably damaging |
Het |
| Taf8 |
A |
T |
17: 47,809,177 (GRCm39) |
|
probably benign |
Het |
| Tars3 |
A |
G |
7: 65,333,829 (GRCm39) |
D617G |
probably damaging |
Het |
| Tbc1d5 |
A |
T |
17: 51,291,715 (GRCm39) |
|
probably benign |
Het |
| Tfcp2 |
C |
G |
15: 100,412,708 (GRCm39) |
E315Q |
probably damaging |
Het |
| Tmf1 |
A |
T |
6: 97,147,345 (GRCm39) |
S540R |
probably damaging |
Het |
| Tmprss4 |
T |
C |
9: 45,095,634 (GRCm39) |
Q70R |
probably benign |
Het |
| Trip13 |
G |
T |
13: 74,068,183 (GRCm39) |
A266E |
possibly damaging |
Het |
| Ttc24 |
T |
A |
3: 87,982,234 (GRCm39) |
|
probably benign |
Het |
| Ttll5 |
T |
A |
12: 85,878,740 (GRCm39) |
I49N |
probably damaging |
Het |
| Tut7 |
G |
A |
13: 59,930,150 (GRCm39) |
R962* |
probably null |
Het |
| Ube2ql1 |
A |
T |
13: 69,886,711 (GRCm39) |
M250K |
possibly damaging |
Het |
| Vmn1r87 |
A |
T |
7: 12,866,211 (GRCm39) |
D25E |
probably damaging |
Het |
| Vmn2r84 |
A |
G |
10: 130,227,877 (GRCm39) |
Y120H |
probably benign |
Het |
| Wdr6 |
G |
A |
9: 108,452,441 (GRCm39) |
R481C |
probably damaging |
Het |
| Zdhhc17 |
A |
T |
10: 110,790,955 (GRCm39) |
Y371* |
probably null |
Het |
| Zfp292 |
T |
C |
4: 34,811,185 (GRCm39) |
N620D |
probably benign |
Het |
| Zfp932 |
T |
A |
5: 110,154,834 (GRCm39) |
Y11N |
probably benign |
Het |
|
| Other mutations in Arid1b |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00325:Arid1b
|
APN |
17 |
5,387,385 (GRCm39) |
missense |
possibly damaging |
0.77 |
|
IGL00340:Arid1b
|
APN |
17 |
5,371,559 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL00886:Arid1b
|
APN |
17 |
5,177,254 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL01161:Arid1b
|
APN |
17 |
5,392,674 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01391:Arid1b
|
APN |
17 |
5,369,133 (GRCm39) |
splice site |
probably benign |
|
|
IGL01456:Arid1b
|
APN |
17 |
5,341,510 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02152:Arid1b
|
APN |
17 |
5,364,243 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02288:Arid1b
|
APN |
17 |
5,314,315 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
IGL02713:Arid1b
|
APN |
17 |
5,393,286 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02858:Arid1b
|
APN |
17 |
5,392,166 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
IGL02885:Arid1b
|
APN |
17 |
5,392,428 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02989:Arid1b
|
APN |
17 |
5,385,322 (GRCm39) |
missense |
probably damaging |
1.00 |
|
FR4449:Arid1b
|
UTSW |
17 |
5,045,864 (GRCm39) |
small insertion |
probably benign |
|
|
PIT4142001:Arid1b
|
UTSW |
17 |
5,389,518 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0048:Arid1b
|
UTSW |
17 |
5,364,309 (GRCm39) |
critical splice donor site |
probably null |
|
|
R0124:Arid1b
|
UTSW |
17 |
5,389,605 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0465:Arid1b
|
UTSW |
17 |
5,046,535 (GRCm39) |
missense |
possibly damaging |
0.68 |
|
R0825:Arid1b
|
UTSW |
17 |
5,392,453 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1172:Arid1b
|
UTSW |
17 |
5,389,575 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1468:Arid1b
|
UTSW |
17 |
5,293,197 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1468:Arid1b
|
UTSW |
17 |
5,293,197 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1616:Arid1b
|
UTSW |
17 |
5,389,569 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1754:Arid1b
|
UTSW |
17 |
5,329,476 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R1760:Arid1b
|
UTSW |
17 |
5,392,088 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R1812:Arid1b
|
UTSW |
17 |
5,387,304 (GRCm39) |
missense |
probably benign |
0.10 |
|
R1911:Arid1b
|
UTSW |
17 |
5,393,241 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3874:Arid1b
|
UTSW |
17 |
5,386,790 (GRCm39) |
splice site |
probably null |
|
|
R3913:Arid1b
|
UTSW |
17 |
5,392,532 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R3916:Arid1b
|
UTSW |
17 |
5,392,928 (GRCm39) |
missense |
probably benign |
0.25 |
|
R3922:Arid1b
|
UTSW |
17 |
5,393,316 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R4119:Arid1b
|
UTSW |
17 |
5,046,069 (GRCm39) |
unclassified |
probably benign |
|
|
R4290:Arid1b
|
UTSW |
17 |
5,090,938 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4291:Arid1b
|
UTSW |
17 |
5,090,938 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4352:Arid1b
|
UTSW |
17 |
5,147,859 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R4386:Arid1b
|
UTSW |
17 |
5,045,247 (GRCm39) |
unclassified |
probably benign |
|
|
R4458:Arid1b
|
UTSW |
17 |
5,293,191 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4524:Arid1b
|
UTSW |
17 |
5,147,895 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R4622:Arid1b
|
UTSW |
17 |
5,045,325 (GRCm39) |
unclassified |
probably benign |
|
|
R4723:Arid1b
|
UTSW |
17 |
5,387,565 (GRCm39) |
missense |
probably benign |
0.01 |
|
R4782:Arid1b
|
UTSW |
17 |
5,389,496 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4799:Arid1b
|
UTSW |
17 |
5,389,496 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4910:Arid1b
|
UTSW |
17 |
5,392,478 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4946:Arid1b
|
UTSW |
17 |
5,393,118 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5083:Arid1b
|
UTSW |
17 |
5,364,293 (GRCm39) |
missense |
possibly damaging |
0.54 |
|
R5204:Arid1b
|
UTSW |
17 |
5,393,316 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R5347:Arid1b
|
UTSW |
17 |
5,341,332 (GRCm39) |
nonsense |
probably null |
|
|
R5553:Arid1b
|
UTSW |
17 |
5,364,152 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5713:Arid1b
|
UTSW |
17 |
5,387,091 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5820:Arid1b
|
UTSW |
17 |
5,046,529 (GRCm39) |
missense |
possibly damaging |
0.96 |
|
R5992:Arid1b
|
UTSW |
17 |
5,045,231 (GRCm39) |
unclassified |
probably benign |
|
|
R6038:Arid1b
|
UTSW |
17 |
5,386,957 (GRCm39) |
missense |
probably benign |
0.07 |
|
R6038:Arid1b
|
UTSW |
17 |
5,386,957 (GRCm39) |
missense |
probably benign |
0.07 |
|
R6153:Arid1b
|
UTSW |
17 |
5,293,107 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6222:Arid1b
|
UTSW |
17 |
5,377,922 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R6249:Arid1b
|
UTSW |
17 |
5,329,636 (GRCm39) |
missense |
possibly damaging |
0.61 |
|
R6279:Arid1b
|
UTSW |
17 |
5,392,274 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6329:Arid1b
|
UTSW |
17 |
5,387,538 (GRCm39) |
nonsense |
probably null |
|
|
R6368:Arid1b
|
UTSW |
17 |
5,382,808 (GRCm39) |
missense |
possibly damaging |
0.64 |
|
R6466:Arid1b
|
UTSW |
17 |
5,377,953 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6861:Arid1b
|
UTSW |
17 |
5,377,961 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R7008:Arid1b
|
UTSW |
17 |
5,341,254 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7270:Arid1b
|
UTSW |
17 |
5,046,318 (GRCm39) |
missense |
unknown |
|
|
R7514:Arid1b
|
UTSW |
17 |
5,391,989 (GRCm39) |
missense |
probably benign |
0.28 |
|
R7519:Arid1b
|
UTSW |
17 |
5,046,128 (GRCm39) |
small insertion |
probably benign |
|
|
R7519:Arid1b
|
UTSW |
17 |
5,046,119 (GRCm39) |
small insertion |
probably benign |
|
|
R7521:Arid1b
|
UTSW |
17 |
5,392,865 (GRCm39) |
missense |
probably benign |
0.06 |
|
R7521:Arid1b
|
UTSW |
17 |
5,046,119 (GRCm39) |
small insertion |
probably benign |
|
|
R7521:Arid1b
|
UTSW |
17 |
5,046,135 (GRCm39) |
small insertion |
probably benign |
|
|
R7616:Arid1b
|
UTSW |
17 |
5,045,661 (GRCm39) |
missense |
unknown |
|
|
R7654:Arid1b
|
UTSW |
17 |
5,341,360 (GRCm39) |
missense |
possibly damaging |
0.46 |
|
R7711:Arid1b
|
UTSW |
17 |
5,387,095 (GRCm39) |
missense |
probably benign |
0.28 |
|
R7828:Arid1b
|
UTSW |
17 |
5,147,943 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7864:Arid1b
|
UTSW |
17 |
5,392,530 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7998:Arid1b
|
UTSW |
17 |
5,377,959 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8105:Arid1b
|
UTSW |
17 |
5,341,518 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
R8260:Arid1b
|
UTSW |
17 |
5,382,788 (GRCm39) |
missense |
probably benign |
0.03 |
|
R8374:Arid1b
|
UTSW |
17 |
5,392,919 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R8779:Arid1b
|
UTSW |
17 |
5,391,809 (GRCm39) |
missense |
probably benign |
0.03 |
|
R8801:Arid1b
|
UTSW |
17 |
5,387,103 (GRCm39) |
missense |
probably benign |
0.05 |
|
R8894:Arid1b
|
UTSW |
17 |
5,377,668 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R8982:Arid1b
|
UTSW |
17 |
5,293,316 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R9034:Arid1b
|
UTSW |
17 |
5,387,180 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9272:Arid1b
|
UTSW |
17 |
5,386,879 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
R9300:Arid1b
|
UTSW |
17 |
5,293,274 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9332:Arid1b
|
UTSW |
17 |
5,045,584 (GRCm39) |
missense |
unknown |
|
|
R9481:Arid1b
|
UTSW |
17 |
5,369,007 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9493:Arid1b
|
UTSW |
17 |
5,046,423 (GRCm39) |
missense |
unknown |
|
|
R9512:Arid1b
|
UTSW |
17 |
5,391,864 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9548:Arid1b
|
UTSW |
17 |
5,385,262 (GRCm39) |
missense |
probably damaging |
1.00 |
|
RF007:Arid1b
|
UTSW |
17 |
5,045,869 (GRCm39) |
small insertion |
probably benign |
|
|
RF008:Arid1b
|
UTSW |
17 |
5,045,870 (GRCm39) |
small insertion |
probably benign |
|
|
RF008:Arid1b
|
UTSW |
17 |
5,045,869 (GRCm39) |
small insertion |
probably benign |
|
|
RF025:Arid1b
|
UTSW |
17 |
5,045,871 (GRCm39) |
small insertion |
probably benign |
|
|
RF025:Arid1b
|
UTSW |
17 |
5,045,863 (GRCm39) |
small insertion |
probably benign |
|
|
RF028:Arid1b
|
UTSW |
17 |
5,045,873 (GRCm39) |
small insertion |
probably benign |
|
|
RF032:Arid1b
|
UTSW |
17 |
5,045,863 (GRCm39) |
small insertion |
probably benign |
|
|
RF033:Arid1b
|
UTSW |
17 |
5,045,860 (GRCm39) |
small insertion |
probably benign |
|
|
RF041:Arid1b
|
UTSW |
17 |
5,045,870 (GRCm39) |
small insertion |
probably benign |
|
|
RF045:Arid1b
|
UTSW |
17 |
5,045,858 (GRCm39) |
small insertion |
probably benign |
|
|
RF046:Arid1b
|
UTSW |
17 |
5,045,865 (GRCm39) |
small insertion |
probably benign |
|
|
RF058:Arid1b
|
UTSW |
17 |
5,045,858 (GRCm39) |
small insertion |
probably benign |
|
|
X0023:Arid1b
|
UTSW |
17 |
5,392,668 (GRCm39) |
missense |
probably benign |
0.39 |
|
X0027:Arid1b
|
UTSW |
17 |
5,392,647 (GRCm39) |
nonsense |
probably null |
|
|
Z1177:Arid1b
|
UTSW |
17 |
5,046,603 (GRCm39) |
missense |
possibly damaging |
0.70 |
|
| Predicted Primers |
PCR Primer
(F):5'- TTGTGCTGGAGACCCTGTGTAAAC -3'
(R):5'- TCACGGATGTCATAACTGCCCAATC -3'
Sequencing Primer
(F):5'- ACAACGTGGACCTGATCTTG -3'
(R):5'- GATGTCATAACTGCCCAATCTGAAAC -3'
|
| Posted On |
2013-04-16 |
Incidental Mutation