Incidental Mutation 'R0153:Adgre1'
| ID |
22878 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Adgre1
|
| Ensembl Gene |
ENSMUSG00000004730 |
| Gene Name |
adhesion G protein-coupled receptor E1 |
| Synonyms |
DD7A5-7, EGF-TM7, Emr1, Ly71, F4/80, TM7LN3 |
| MMRRC Submission |
038436-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.188)
|
| Stock # |
R0153 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
(trace)
|
| Chromosome |
17 |
| Chromosomal Location |
57665691-57790527 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to A
at 57750939 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Serine to Threonine
at position 538
(S538T)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000083971
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000004850]
[ENSMUST00000086763]
|
| AlphaFold |
Q61549 |
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000004850
AA Change: S538T
PolyPhen 2
Score 0.921 (Sensitivity: 0.81; Specificity: 0.94)
|
| SMART Domains |
Protein: ENSMUSP00000004850
Gene: ENSMUSG00000004730
AA Change: S538T
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
19 |
32 |
N/A |
INTRINSIC |
|
EGF
|
35 |
80 |
1.43e-1 |
SMART |
|
EGF_CA
|
81 |
122 |
3.59e-7 |
SMART |
|
EGF_CA
|
133 |
172 |
4.56e-9 |
SMART |
|
EGF_CA
|
173 |
221 |
1.29e-8 |
SMART |
|
EGF_CA
|
222 |
271 |
2.31e-10 |
SMART |
|
EGF_CA
|
272 |
318 |
1.06e-9 |
SMART |
|
EGF_CA
|
319 |
367 |
1.18e-7 |
SMART |
|
GPS
|
591 |
641 |
2.57e-19 |
SMART |
|
Pfam:7tm_2
|
644 |
885 |
2.1e-63 |
PFAM |
|
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000086763
AA Change: S538T
PolyPhen 2
Score 0.921 (Sensitivity: 0.81; Specificity: 0.94)
|
| SMART Domains |
Protein: ENSMUSP00000083971
Gene: ENSMUSG00000004730
AA Change: S538T
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
19 |
32 |
N/A |
INTRINSIC |
|
EGF
|
35 |
80 |
1.43e-1 |
SMART |
|
EGF_CA
|
81 |
122 |
3.59e-7 |
SMART |
|
EGF_CA
|
133 |
172 |
4.56e-9 |
SMART |
|
EGF_CA
|
173 |
221 |
1.29e-8 |
SMART |
|
EGF_CA
|
222 |
271 |
2.31e-10 |
SMART |
|
EGF_CA
|
272 |
318 |
1.06e-9 |
SMART |
|
EGF_CA
|
319 |
367 |
1.18e-7 |
SMART |
|
GPS
|
591 |
641 |
2.57e-19 |
SMART |
|
Pfam:7tm_2
|
644 |
885 |
2.1e-63 |
PFAM |
|
| Meta Mutation Damage Score |
0.1501 |
| Coding Region Coverage |
- 1x: 98.9%
- 3x: 98.0%
- 10x: 95.5%
- 20x: 90.1%
|
| Validation Efficiency |
97% (99/102) |
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a protein that has a domain resembling seven transmembrane G protein-coupled hormone receptors (7TM receptors) at its C-terminus. The N-terminus of the encoded protein has six EGF-like modules, separated from the transmembrane segments by a serine/threonine-rich domain, a feature reminiscent of mucin-like, single-span, integral membrane glycoproteins with adhesive properties. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012]
PHENOTYPE: Homozygous null mice fail to develop peripheral tolerance after inoculation with antigen because of a lack of efferent regulatory T cell development. [provided by MGI curators]
|
| Allele List at MGI |
All alleles(4) : Targeted(3) Chemically induced(1)
|
| Other mutations in this stock |
Total: 85 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Abcb9 |
T |
C |
5: 124,218,119 (GRCm39) |
M406V |
probably benign |
Het |
| Adar |
T |
C |
3: 89,638,121 (GRCm39) |
S2P |
probably benign |
Het |
| Alms1 |
T |
A |
6: 85,618,363 (GRCm39) |
I2803N |
possibly damaging |
Het |
| Amn1 |
G |
T |
6: 149,090,091 (GRCm39) |
|
probably benign |
Het |
| Arid1b |
G |
A |
17: 5,393,207 (GRCm39) |
A2246T |
probably damaging |
Het |
| BC024139 |
T |
C |
15: 76,005,947 (GRCm39) |
E418G |
probably damaging |
Het |
| Bok |
A |
G |
1: 93,614,239 (GRCm39) |
D24G |
probably damaging |
Het |
| Cabp2 |
T |
C |
19: 4,134,913 (GRCm39) |
|
probably benign |
Het |
| Ccdc141 |
C |
A |
2: 76,995,582 (GRCm39) |
|
probably benign |
Het |
| Ccdc178 |
T |
C |
18: 22,283,492 (GRCm39) |
T13A |
probably benign |
Het |
| Ccdc42 |
G |
T |
11: 68,478,476 (GRCm39) |
V33F |
possibly damaging |
Het |
| Clcn7 |
G |
A |
17: 25,368,176 (GRCm39) |
|
probably benign |
Het |
| Cluh |
A |
G |
11: 74,548,176 (GRCm39) |
|
probably benign |
Het |
| Cr1l |
A |
T |
1: 194,797,164 (GRCm39) |
|
probably benign |
Het |
| Cracdl |
A |
G |
1: 37,663,720 (GRCm39) |
V726A |
probably benign |
Het |
| Csnk1g3 |
T |
A |
18: 54,051,861 (GRCm39) |
|
probably benign |
Het |
| Depdc5 |
T |
C |
5: 33,091,281 (GRCm39) |
|
probably benign |
Het |
| Dgkh |
A |
C |
14: 78,807,569 (GRCm39) |
Y1149* |
probably null |
Het |
| Dipk2a |
G |
T |
9: 94,406,533 (GRCm39) |
D291E |
probably benign |
Het |
| Dnai1 |
A |
G |
4: 41,635,162 (GRCm39) |
|
probably benign |
Het |
| Dync2i1 |
A |
G |
12: 116,196,256 (GRCm39) |
V497A |
probably benign |
Het |
| Efcab2 |
A |
G |
1: 178,302,451 (GRCm39) |
E65G |
possibly damaging |
Het |
| Eif4a3l1 |
A |
T |
6: 136,305,842 (GRCm39) |
D101V |
probably damaging |
Het |
| Eno1b |
T |
C |
18: 48,180,806 (GRCm39) |
I328T |
probably benign |
Het |
| Fgfr4 |
A |
G |
13: 55,309,198 (GRCm39) |
|
probably benign |
Het |
| Garin5b |
A |
T |
7: 4,773,286 (GRCm39) |
L177Q |
probably damaging |
Het |
| Gm10720 |
A |
C |
9: 3,015,787 (GRCm39) |
S44R |
probably null |
Het |
| Gm17535 |
T |
A |
9: 3,035,786 (GRCm39) |
L218H |
probably benign |
Het |
| Gm6471 |
A |
T |
7: 142,385,368 (GRCm39) |
|
noncoding transcript |
Het |
| Hnrnpm |
C |
T |
17: 33,865,489 (GRCm39) |
R724Q |
probably damaging |
Het |
| Homer1 |
C |
T |
13: 93,528,254 (GRCm39) |
T117I |
possibly damaging |
Het |
| Hoxd4 |
A |
T |
2: 74,557,801 (GRCm39) |
Q60L |
probably damaging |
Het |
| Ift172 |
T |
C |
5: 31,417,968 (GRCm39) |
R1274G |
probably benign |
Het |
| Ino80d |
A |
G |
1: 63,097,477 (GRCm39) |
S806P |
probably damaging |
Het |
| Itga10 |
T |
C |
3: 96,561,016 (GRCm39) |
V627A |
probably benign |
Het |
| Itgb2l |
A |
G |
16: 96,238,569 (GRCm39) |
Y77H |
possibly damaging |
Het |
| Kel |
A |
T |
6: 41,678,877 (GRCm39) |
H195Q |
probably benign |
Het |
| Klhdc7a |
A |
G |
4: 139,694,582 (GRCm39) |
S122P |
possibly damaging |
Het |
| Krt71 |
T |
A |
15: 101,643,141 (GRCm39) |
I456F |
possibly damaging |
Het |
| Lats1 |
T |
A |
10: 7,567,339 (GRCm39) |
S37T |
probably damaging |
Het |
| Lrp1b |
T |
A |
2: 41,013,031 (GRCm39) |
H1858L |
possibly damaging |
Het |
| Matk |
A |
T |
10: 81,098,676 (GRCm39) |
T461S |
probably benign |
Het |
| Meikin |
A |
G |
11: 54,300,468 (GRCm39) |
|
probably benign |
Het |
| Muc6 |
T |
C |
7: 141,214,029 (GRCm39) |
Q2832R |
possibly damaging |
Het |
| Myo10 |
T |
C |
15: 25,781,324 (GRCm39) |
F194L |
possibly damaging |
Het |
| Nbas |
G |
A |
12: 13,323,877 (GRCm39) |
|
probably benign |
Het |
| Nme4 |
A |
G |
17: 26,312,831 (GRCm39) |
|
probably null |
Het |
| Or13p8 |
A |
T |
4: 118,583,530 (GRCm39) |
I29F |
possibly damaging |
Het |
| Or4c112 |
T |
A |
2: 88,853,540 (GRCm39) |
N269I |
probably benign |
Het |
| Or5w13 |
A |
G |
2: 87,523,948 (GRCm39) |
S93P |
probably benign |
Het |
| Or7g32 |
T |
A |
9: 19,408,233 (GRCm39) |
L63H |
probably damaging |
Het |
| Or8g34 |
T |
C |
9: 39,372,967 (GRCm39) |
V80A |
probably damaging |
Het |
| Pacsin2 |
T |
C |
15: 83,261,862 (GRCm39) |
Q473R |
probably benign |
Het |
| Patz1 |
A |
G |
11: 3,243,288 (GRCm39) |
H427R |
probably damaging |
Het |
| Pkp3 |
A |
G |
7: 140,663,256 (GRCm39) |
Y367C |
probably damaging |
Het |
| Prdm2 |
G |
A |
4: 142,860,338 (GRCm39) |
P984L |
possibly damaging |
Het |
| Rev3l |
T |
A |
10: 39,750,124 (GRCm39) |
C3091* |
probably null |
Het |
| Rims4 |
C |
T |
2: 163,705,849 (GRCm39) |
V262M |
possibly damaging |
Het |
| Rpl5 |
T |
C |
5: 108,052,623 (GRCm39) |
F140L |
probably benign |
Het |
| Sec24a |
A |
C |
11: 51,591,653 (GRCm39) |
I1014M |
probably benign |
Het |
| Serpinb11 |
A |
G |
1: 107,299,933 (GRCm39) |
H93R |
probably benign |
Het |
| Shank2 |
C |
A |
7: 143,623,872 (GRCm39) |
H286N |
probably benign |
Het |
| Sipa1l2 |
G |
T |
8: 126,148,637 (GRCm39) |
Q1651K |
probably damaging |
Het |
| Slc17a3 |
C |
T |
13: 24,039,841 (GRCm39) |
S293F |
probably damaging |
Het |
| Slc30a5 |
A |
T |
13: 100,963,002 (GRCm39) |
F75L |
possibly damaging |
Het |
| Slco1a1 |
G |
T |
6: 141,856,427 (GRCm39) |
|
probably benign |
Het |
| Smg5 |
C |
T |
3: 88,261,179 (GRCm39) |
|
probably benign |
Het |
| Snapc1 |
C |
T |
12: 74,021,806 (GRCm39) |
R81C |
probably damaging |
Het |
| Taf8 |
A |
T |
17: 47,809,177 (GRCm39) |
|
probably benign |
Het |
| Tars3 |
A |
G |
7: 65,333,829 (GRCm39) |
D617G |
probably damaging |
Het |
| Tbc1d5 |
A |
T |
17: 51,291,715 (GRCm39) |
|
probably benign |
Het |
| Tfcp2 |
C |
G |
15: 100,412,708 (GRCm39) |
E315Q |
probably damaging |
Het |
| Tmf1 |
A |
T |
6: 97,147,345 (GRCm39) |
S540R |
probably damaging |
Het |
| Tmprss4 |
T |
C |
9: 45,095,634 (GRCm39) |
Q70R |
probably benign |
Het |
| Trip13 |
G |
T |
13: 74,068,183 (GRCm39) |
A266E |
possibly damaging |
Het |
| Ttc24 |
T |
A |
3: 87,982,234 (GRCm39) |
|
probably benign |
Het |
| Ttll5 |
T |
A |
12: 85,878,740 (GRCm39) |
I49N |
probably damaging |
Het |
| Tut7 |
G |
A |
13: 59,930,150 (GRCm39) |
R962* |
probably null |
Het |
| Ube2ql1 |
A |
T |
13: 69,886,711 (GRCm39) |
M250K |
possibly damaging |
Het |
| Vmn1r87 |
A |
T |
7: 12,866,211 (GRCm39) |
D25E |
probably damaging |
Het |
| Vmn2r84 |
A |
G |
10: 130,227,877 (GRCm39) |
Y120H |
probably benign |
Het |
| Wdr6 |
G |
A |
9: 108,452,441 (GRCm39) |
R481C |
probably damaging |
Het |
| Zdhhc17 |
A |
T |
10: 110,790,955 (GRCm39) |
Y371* |
probably null |
Het |
| Zfp292 |
T |
C |
4: 34,811,185 (GRCm39) |
N620D |
probably benign |
Het |
| Zfp932 |
T |
A |
5: 110,154,834 (GRCm39) |
Y11N |
probably benign |
Het |
|
| Other mutations in Adgre1 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00090:Adgre1
|
APN |
17 |
57,757,055 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL00966:Adgre1
|
APN |
17 |
57,726,335 (GRCm39) |
missense |
probably benign |
0.04 |
|
IGL01680:Adgre1
|
APN |
17 |
57,709,620 (GRCm39) |
missense |
unknown |
|
|
IGL01724:Adgre1
|
APN |
17 |
57,751,064 (GRCm39) |
nonsense |
probably null |
|
|
IGL02172:Adgre1
|
APN |
17 |
57,785,879 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02260:Adgre1
|
APN |
17 |
57,754,891 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL02272:Adgre1
|
APN |
17 |
57,757,021 (GRCm39) |
nonsense |
probably null |
|
|
IGL02336:Adgre1
|
APN |
17 |
57,718,024 (GRCm39) |
nonsense |
probably null |
|
|
IGL02346:Adgre1
|
APN |
17 |
57,750,919 (GRCm39) |
missense |
probably benign |
0.15 |
|
IGL02398:Adgre1
|
APN |
17 |
57,709,824 (GRCm39) |
nonsense |
probably null |
|
|
IGL02618:Adgre1
|
APN |
17 |
57,751,021 (GRCm39) |
missense |
possibly damaging |
0.66 |
|
IGL02690:Adgre1
|
APN |
17 |
57,787,921 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02936:Adgre1
|
APN |
17 |
57,785,833 (GRCm39) |
missense |
probably benign |
0.26 |
|
IGL03112:Adgre1
|
APN |
17 |
57,755,029 (GRCm39) |
splice site |
probably null |
|
|
IGL03350:Adgre1
|
APN |
17 |
57,708,908 (GRCm39) |
missense |
probably benign |
0.16 |
|
F480
|
UTSW |
17 |
57,751,063 (GRCm39) |
missense |
probably damaging |
1.00 |
|
lomax
|
UTSW |
17 |
57,709,811 (GRCm39) |
missense |
unknown |
|
|
Onion
|
UTSW |
17 |
57,709,841 (GRCm39) |
nonsense |
probably null |
|
|
Scallion
|
UTSW |
17 |
57,708,977 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R0049:Adgre1
|
UTSW |
17 |
57,709,841 (GRCm39) |
nonsense |
probably null |
|
|
R0277:Adgre1
|
UTSW |
17 |
57,751,060 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0278:Adgre1
|
UTSW |
17 |
57,754,872 (GRCm39) |
missense |
probably benign |
0.07 |
|
R0323:Adgre1
|
UTSW |
17 |
57,751,060 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0389:Adgre1
|
UTSW |
17 |
57,713,839 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
R0492:Adgre1
|
UTSW |
17 |
57,709,742 (GRCm39) |
missense |
unknown |
|
|
R0621:Adgre1
|
UTSW |
17 |
57,748,359 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R0647:Adgre1
|
UTSW |
17 |
57,718,003 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1310:Adgre1
|
UTSW |
17 |
57,754,936 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1601:Adgre1
|
UTSW |
17 |
57,748,353 (GRCm39) |
missense |
probably benign |
0.01 |
|
R1689:Adgre1
|
UTSW |
17 |
57,756,921 (GRCm39) |
missense |
probably benign |
0.31 |
|
R1708:Adgre1
|
UTSW |
17 |
57,708,974 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R1796:Adgre1
|
UTSW |
17 |
57,748,350 (GRCm39) |
missense |
probably benign |
0.43 |
|
R1839:Adgre1
|
UTSW |
17 |
57,748,299 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1860:Adgre1
|
UTSW |
17 |
57,748,363 (GRCm39) |
missense |
probably benign |
0.00 |
|
R2165:Adgre1
|
UTSW |
17 |
57,726,338 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R2219:Adgre1
|
UTSW |
17 |
57,708,912 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R2519:Adgre1
|
UTSW |
17 |
57,717,956 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3874:Adgre1
|
UTSW |
17 |
57,708,925 (GRCm39) |
missense |
probably benign |
0.08 |
|
R3911:Adgre1
|
UTSW |
17 |
57,754,860 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4190:Adgre1
|
UTSW |
17 |
57,709,811 (GRCm39) |
missense |
unknown |
|
|
R4439:Adgre1
|
UTSW |
17 |
57,754,954 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4513:Adgre1
|
UTSW |
17 |
57,717,947 (GRCm39) |
missense |
probably benign |
0.34 |
|
R4529:Adgre1
|
UTSW |
17 |
57,727,519 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R4543:Adgre1
|
UTSW |
17 |
57,713,874 (GRCm39) |
missense |
probably benign |
0.07 |
|
R4610:Adgre1
|
UTSW |
17 |
57,757,073 (GRCm39) |
missense |
possibly damaging |
0.50 |
|
R4665:Adgre1
|
UTSW |
17 |
57,787,947 (GRCm39) |
missense |
probably benign |
0.20 |
|
R4911:Adgre1
|
UTSW |
17 |
57,754,832 (GRCm39) |
missense |
possibly damaging |
0.57 |
|
R4928:Adgre1
|
UTSW |
17 |
57,751,064 (GRCm39) |
nonsense |
probably null |
|
|
R4942:Adgre1
|
UTSW |
17 |
57,713,903 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4946:Adgre1
|
UTSW |
17 |
57,750,918 (GRCm39) |
missense |
probably benign |
0.33 |
|
R4953:Adgre1
|
UTSW |
17 |
57,748,321 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5107:Adgre1
|
UTSW |
17 |
57,708,977 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R5366:Adgre1
|
UTSW |
17 |
57,709,817 (GRCm39) |
missense |
probably benign |
0.39 |
|
R5590:Adgre1
|
UTSW |
17 |
57,752,034 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5619:Adgre1
|
UTSW |
17 |
57,727,437 (GRCm39) |
missense |
probably benign |
0.15 |
|
R5699:Adgre1
|
UTSW |
17 |
57,788,007 (GRCm39) |
missense |
probably benign |
0.43 |
|
R5734:Adgre1
|
UTSW |
17 |
57,750,990 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5860:Adgre1
|
UTSW |
17 |
57,752,034 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6039:Adgre1
|
UTSW |
17 |
57,713,859 (GRCm39) |
missense |
probably benign |
0.28 |
|
R6039:Adgre1
|
UTSW |
17 |
57,713,859 (GRCm39) |
missense |
probably benign |
0.28 |
|
R6149:Adgre1
|
UTSW |
17 |
57,752,018 (GRCm39) |
missense |
probably benign |
0.08 |
|
R6478:Adgre1
|
UTSW |
17 |
57,708,955 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
R6709:Adgre1
|
UTSW |
17 |
57,713,917 (GRCm39) |
missense |
probably benign |
0.10 |
|
R6864:Adgre1
|
UTSW |
17 |
57,785,879 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6945:Adgre1
|
UTSW |
17 |
57,727,399 (GRCm39) |
missense |
probably benign |
0.39 |
|
R6945:Adgre1
|
UTSW |
17 |
57,717,844 (GRCm39) |
missense |
probably benign |
0.01 |
|
R6988:Adgre1
|
UTSW |
17 |
57,715,445 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7019:Adgre1
|
UTSW |
17 |
57,717,945 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R7154:Adgre1
|
UTSW |
17 |
57,751,087 (GRCm39) |
splice site |
probably null |
|
|
R7347:Adgre1
|
UTSW |
17 |
57,727,441 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7459:Adgre1
|
UTSW |
17 |
57,756,933 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7709:Adgre1
|
UTSW |
17 |
57,709,519 (GRCm39) |
missense |
unknown |
|
|
R7939:Adgre1
|
UTSW |
17 |
57,756,938 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R7977:Adgre1
|
UTSW |
17 |
57,754,987 (GRCm39) |
missense |
possibly damaging |
0.54 |
|
R7987:Adgre1
|
UTSW |
17 |
57,754,987 (GRCm39) |
missense |
possibly damaging |
0.54 |
|
R8187:Adgre1
|
UTSW |
17 |
57,727,349 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8210:Adgre1
|
UTSW |
17 |
57,752,061 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R8223:Adgre1
|
UTSW |
17 |
57,668,692 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8344:Adgre1
|
UTSW |
17 |
57,715,459 (GRCm39) |
missense |
probably benign |
0.12 |
|
R8698:Adgre1
|
UTSW |
17 |
57,709,003 (GRCm39) |
missense |
probably benign |
0.05 |
|
R9236:Adgre1
|
UTSW |
17 |
57,709,782 (GRCm39) |
nonsense |
probably null |
|
|
R9262:Adgre1
|
UTSW |
17 |
57,754,941 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9303:Adgre1
|
UTSW |
17 |
57,748,275 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9305:Adgre1
|
UTSW |
17 |
57,748,275 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9605:Adgre1
|
UTSW |
17 |
57,718,083 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9661:Adgre1
|
UTSW |
17 |
57,748,368 (GRCm39) |
missense |
possibly damaging |
0.70 |
|
R9678:Adgre1
|
UTSW |
17 |
57,750,997 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R9751:Adgre1
|
UTSW |
17 |
57,757,101 (GRCm39) |
missense |
probably null |
0.06 |
|
R9785:Adgre1
|
UTSW |
17 |
57,785,930 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1176:Adgre1
|
UTSW |
17 |
57,668,729 (GRCm39) |
missense |
possibly damaging |
0.76 |
|
Z1177:Adgre1
|
UTSW |
17 |
57,726,374 (GRCm39) |
missense |
probably damaging |
0.96 |
|
| Predicted Primers |
PCR Primer
(F):5'- ATGTTGCTCCACAGGCCATTGG -3'
(R):5'- AACCTGGATGTGCTGGAGGGTATAG -3'
Sequencing Primer
(F):5'- GCCTCAACTGATCTGAAAATTCTTGG -3'
(R):5'- TAGATAATAGGCTTGGAGAAGTCCTC -3'
|
| Posted On |
2013-04-16 |
Incidental Mutation