Incidental Mutation 'R2116:Gcn1'
| ID |
233134 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Gcn1
|
| Ensembl Gene |
ENSMUSG00000041638 |
| Gene Name |
GCN1 activator of EIF2AK4 |
| Synonyms |
Gcn1l1, G431004K08Rik, GCN1L |
| MMRRC Submission |
040120-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably essential
(E-score: 0.948)
|
| Stock # |
R2116 (G1)
|
| Quality Score |
225 |
|
Status
|
Not validated
|
| Chromosome |
5 |
| Chromosomal Location |
115703313-115760713 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to T
at 115736884 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Methionine to Leucine
at position 1276
(M1276L)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000069432
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000064454]
|
| AlphaFold |
E9PVA8 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000064454
AA Change: M1276L
PolyPhen 2
Score 0.351 (Sensitivity: 0.90; Specificity: 0.89)
|
| SMART Domains |
Protein: ENSMUSP00000069432
Gene: ENSMUSG00000041638
AA Change: M1276L
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
64 |
84 |
N/A |
INTRINSIC |
|
low complexity region
|
108 |
117 |
N/A |
INTRINSIC |
|
low complexity region
|
142 |
154 |
N/A |
INTRINSIC |
|
Pfam:DUF3554
|
357 |
705 |
2e-61 |
PFAM |
|
coiled coil region
|
806 |
866 |
N/A |
INTRINSIC |
|
Blast:ARM
|
1028 |
1068 |
6e-11 |
BLAST |
|
coiled coil region
|
1180 |
1203 |
N/A |
INTRINSIC |
|
low complexity region
|
1457 |
1466 |
N/A |
INTRINSIC |
|
low complexity region
|
1501 |
1510 |
N/A |
INTRINSIC |
|
ARM
|
1527 |
1567 |
3.69e1 |
SMART |
|
Blast:ARM
|
1602 |
1644 |
1e-5 |
BLAST |
|
Blast:EZ_HEAT
|
1671 |
1704 |
1e-7 |
BLAST |
|
low complexity region
|
1926 |
1934 |
N/A |
INTRINSIC |
|
low complexity region
|
1956 |
1972 |
N/A |
INTRINSIC |
|
ARM
|
2034 |
2070 |
9.27e1 |
SMART |
|
low complexity region
|
2326 |
2334 |
N/A |
INTRINSIC |
|
ARM
|
2416 |
2455 |
2.16e1 |
SMART |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000151030
AA Change: H877L
|
| Coding Region Coverage |
- 1x: 99.2%
- 3x: 98.6%
- 10x: 97.5%
- 20x: 95.9%
|
| Validation Efficiency |
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 96 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Adamts20 |
A |
G |
15: 94,253,243 (GRCm39) |
C377R |
probably damaging |
Het |
| Adgrv1 |
T |
C |
13: 81,677,132 (GRCm39) |
K1180E |
probably benign |
Het |
| Ankle1 |
A |
G |
8: 71,860,562 (GRCm39) |
T340A |
probably benign |
Het |
| Armc2 |
A |
T |
10: 41,839,663 (GRCm39) |
L434Q |
probably damaging |
Het |
| Ash1l |
C |
T |
3: 88,890,571 (GRCm39) |
L817F |
probably benign |
Het |
| Atm |
C |
T |
9: 53,412,269 (GRCm39) |
E960K |
probably benign |
Het |
| Bend5 |
G |
T |
4: 111,272,436 (GRCm39) |
R22L |
probably benign |
Het |
| Cacng6 |
C |
T |
7: 3,479,020 (GRCm39) |
T133I |
probably damaging |
Het |
| Cep120 |
G |
A |
18: 53,873,208 (GRCm39) |
T41I |
probably damaging |
Het |
| Ciz1 |
T |
C |
2: 32,257,477 (GRCm39) |
L174P |
probably damaging |
Het |
| Cmah |
G |
A |
13: 24,612,880 (GRCm39) |
D26N |
probably benign |
Het |
| Cnot1 |
A |
C |
8: 96,452,781 (GRCm39) |
D2098E |
probably damaging |
Het |
| Cnot10 |
A |
C |
9: 114,455,504 (GRCm39) |
S207R |
probably damaging |
Het |
| Col14a1 |
A |
G |
15: 55,271,160 (GRCm39) |
T638A |
unknown |
Het |
| Coro1a |
T |
C |
7: 126,301,194 (GRCm39) |
E102G |
probably damaging |
Het |
| Ddx27 |
A |
C |
2: 166,869,684 (GRCm39) |
D373A |
probably benign |
Het |
| Defb38 |
A |
T |
8: 19,073,483 (GRCm39) |
Y63* |
probably null |
Het |
| Dhx37 |
A |
G |
5: 125,498,166 (GRCm39) |
V681A |
probably damaging |
Het |
| Dmxl1 |
T |
A |
18: 50,011,884 (GRCm39) |
L1347H |
probably damaging |
Het |
| Dnmt3l |
C |
A |
10: 77,899,130 (GRCm39) |
L110I |
probably damaging |
Het |
| Gfus |
A |
G |
15: 75,797,991 (GRCm39) |
F223S |
probably damaging |
Het |
| Gm10277 |
TC |
T |
11: 77,676,828 (GRCm39) |
|
probably null |
Het |
| Gm12790 |
G |
A |
4: 101,824,848 (GRCm39) |
T140I |
possibly damaging |
Het |
| Golga3 |
A |
T |
5: 110,335,261 (GRCm39) |
M192L |
probably damaging |
Het |
| H2-T22 |
A |
T |
17: 36,349,949 (GRCm39) |
|
probably null |
Het |
| Hectd2 |
C |
A |
19: 36,591,824 (GRCm39) |
T675K |
probably damaging |
Het |
| Hinfp |
T |
C |
9: 44,210,912 (GRCm39) |
N116S |
probably damaging |
Het |
| Hoatz |
A |
G |
9: 51,012,384 (GRCm39) |
S79P |
possibly damaging |
Het |
| Hs6st3 |
T |
A |
14: 120,106,699 (GRCm39) |
L369Q |
probably damaging |
Het |
| Ift74 |
A |
G |
4: 94,515,496 (GRCm39) |
T138A |
probably benign |
Het |
| Ipo7 |
T |
A |
7: 109,650,325 (GRCm39) |
Y792N |
probably damaging |
Het |
| Jak1 |
A |
T |
4: 101,036,872 (GRCm39) |
I256N |
probably damaging |
Het |
| Kcnd2 |
T |
A |
6: 21,216,431 (GRCm39) |
L45Q |
probably damaging |
Het |
| Klhl3 |
A |
T |
13: 58,166,805 (GRCm39) |
V342E |
probably damaging |
Het |
| Krt28 |
A |
C |
11: 99,255,943 (GRCm39) |
S439A |
probably benign |
Het |
| L3mbtl1 |
T |
A |
2: 162,801,990 (GRCm39) |
|
probably null |
Het |
| Lrch1 |
G |
A |
14: 75,022,971 (GRCm39) |
P634L |
probably damaging |
Het |
| Lrp1 |
C |
T |
10: 127,412,362 (GRCm39) |
W1314* |
probably null |
Het |
| Lrwd1 |
T |
A |
5: 136,159,332 (GRCm39) |
Y431F |
probably damaging |
Het |
| Lyst |
A |
G |
13: 13,810,286 (GRCm39) |
E652G |
probably damaging |
Het |
| Mageb3 |
A |
G |
2: 121,785,033 (GRCm39) |
V223A |
probably damaging |
Het |
| Map1b |
G |
T |
13: 99,567,152 (GRCm39) |
S1856R |
unknown |
Het |
| Mecom |
T |
A |
3: 30,019,607 (GRCm39) |
Q759L |
probably damaging |
Het |
| Mfsd6 |
T |
A |
1: 52,700,134 (GRCm39) |
R671S |
probably benign |
Het |
| Mllt10 |
A |
G |
2: 18,167,380 (GRCm39) |
N435S |
probably benign |
Het |
| Mta2 |
T |
C |
19: 8,920,880 (GRCm39) |
I27T |
probably damaging |
Het |
| Ndufab1 |
A |
G |
7: 121,700,987 (GRCm39) |
L20P |
probably benign |
Het |
| Nfatc2ip |
T |
A |
7: 125,984,280 (GRCm39) |
Y371F |
probably damaging |
Het |
| Nhlrc1 |
A |
C |
13: 47,167,661 (GRCm39) |
S199A |
probably benign |
Het |
| Nipa1 |
G |
T |
7: 55,635,273 (GRCm39) |
N113K |
possibly damaging |
Het |
| Nlgn1 |
T |
A |
3: 26,187,414 (GRCm39) |
N157I |
probably damaging |
Het |
| Nlrp1a |
T |
A |
11: 71,005,326 (GRCm39) |
K630* |
probably null |
Het |
| Nmi |
T |
C |
2: 51,838,719 (GRCm39) |
T272A |
probably benign |
Het |
| Nr1i3 |
T |
A |
1: 171,046,163 (GRCm39) |
L181Q |
probably damaging |
Het |
| Nrxn1 |
A |
T |
17: 91,011,705 (GRCm39) |
I308K |
probably damaging |
Het |
| Nup50l |
A |
T |
6: 96,141,841 (GRCm39) |
V401E |
probably damaging |
Het |
| Or14a256 |
T |
C |
7: 86,265,286 (GRCm39) |
D189G |
probably benign |
Het |
| Or52z15 |
T |
C |
7: 103,332,519 (GRCm39) |
I188T |
probably damaging |
Het |
| Or5al7 |
A |
T |
2: 85,993,073 (GRCm39) |
Y73* |
probably null |
Het |
| Or8g50 |
T |
A |
9: 39,648,600 (GRCm39) |
M163K |
probably damaging |
Het |
| Osgin2 |
G |
A |
4: 16,008,648 (GRCm39) |
T51M |
probably damaging |
Het |
| Pkd1l2 |
T |
A |
8: 117,757,461 (GRCm39) |
T1526S |
possibly damaging |
Het |
| Pkhd1l1 |
G |
T |
15: 44,432,878 (GRCm39) |
A3378S |
probably damaging |
Het |
| Plg |
A |
T |
17: 12,603,364 (GRCm39) |
D90V |
probably damaging |
Het |
| Plppr3 |
A |
T |
10: 79,701,572 (GRCm39) |
D423E |
probably benign |
Het |
| Prpf8 |
T |
C |
11: 75,378,547 (GRCm39) |
V66A |
possibly damaging |
Het |
| Psg19 |
A |
T |
7: 18,528,180 (GRCm39) |
Y188N |
probably damaging |
Het |
| Ptgs1 |
C |
A |
2: 36,127,708 (GRCm39) |
S89* |
probably null |
Het |
| Ptx3 |
T |
A |
3: 66,132,187 (GRCm39) |
I236N |
probably damaging |
Het |
| Pygm |
A |
G |
19: 6,436,438 (GRCm39) |
N100S |
probably damaging |
Het |
| Reps1 |
A |
G |
10: 18,000,668 (GRCm39) |
E760G |
probably damaging |
Het |
| Rgs7 |
T |
A |
1: 174,918,639 (GRCm39) |
N235I |
probably damaging |
Het |
| Rgsl1 |
T |
A |
1: 153,693,295 (GRCm39) |
M629L |
probably benign |
Het |
| Rrh |
T |
C |
3: 129,604,336 (GRCm39) |
I288M |
probably damaging |
Het |
| Sctr |
A |
T |
1: 119,959,312 (GRCm39) |
D70V |
probably damaging |
Het |
| Sec11c |
A |
T |
18: 65,933,720 (GRCm39) |
T9S |
probably benign |
Het |
| Spty2d1 |
C |
T |
7: 46,645,933 (GRCm39) |
G570D |
probably damaging |
Het |
| Stx1b |
T |
C |
7: 127,410,077 (GRCm39) |
E153G |
probably damaging |
Het |
| Synm |
G |
A |
7: 67,383,343 (GRCm39) |
R1440W |
probably benign |
Het |
| Tcof1 |
T |
C |
18: 60,965,857 (GRCm39) |
E415G |
possibly damaging |
Het |
| Tgfb1i1 |
G |
A |
7: 127,851,977 (GRCm39) |
R353H |
probably damaging |
Het |
| Thbs3 |
T |
C |
3: 89,126,699 (GRCm39) |
F271S |
probably damaging |
Het |
| Tlr5 |
T |
C |
1: 182,803,194 (GRCm39) |
W833R |
probably damaging |
Het |
| Tmem132b |
A |
G |
5: 125,699,615 (GRCm39) |
E92G |
probably damaging |
Het |
| Tmem221 |
T |
C |
8: 72,010,472 (GRCm39) |
Y133C |
probably damaging |
Het |
| Tmem229b-ps |
A |
G |
10: 53,351,552 (GRCm39) |
|
noncoding transcript |
Het |
| Tnxb |
T |
C |
17: 34,891,201 (GRCm39) |
C515R |
probably damaging |
Het |
| Trp53rka |
T |
A |
2: 165,333,415 (GRCm39) |
N158I |
probably damaging |
Het |
| Usp20 |
T |
A |
2: 30,906,317 (GRCm39) |
C562S |
probably damaging |
Het |
| Usp31 |
C |
T |
7: 121,247,919 (GRCm39) |
V1175M |
probably benign |
Het |
| Veph1 |
G |
T |
3: 65,964,610 (GRCm39) |
N806K |
probably benign |
Het |
| Vmn1r223 |
G |
T |
13: 23,433,832 (GRCm39) |
C142F |
probably damaging |
Het |
| Vmn2r80 |
A |
T |
10: 79,030,558 (GRCm39) |
S795C |
probably benign |
Het |
| Wdr41 |
A |
G |
13: 95,151,537 (GRCm39) |
|
probably null |
Het |
| Zfp617 |
A |
T |
8: 72,686,009 (GRCm39) |
H113L |
probably benign |
Het |
| Zfp715 |
T |
A |
7: 42,947,370 (GRCm39) |
R863S |
possibly damaging |
Het |
|
| Other mutations in Gcn1 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00869:Gcn1
|
APN |
5 |
115,726,202 (GRCm39) |
splice site |
probably benign |
|
|
IGL00974:Gcn1
|
APN |
5 |
115,751,852 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
IGL01566:Gcn1
|
APN |
5 |
115,749,117 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01843:Gcn1
|
APN |
5 |
115,757,759 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01885:Gcn1
|
APN |
5 |
115,714,174 (GRCm39) |
splice site |
probably null |
|
|
IGL02081:Gcn1
|
APN |
5 |
115,723,930 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02118:Gcn1
|
APN |
5 |
115,748,938 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02150:Gcn1
|
APN |
5 |
115,747,927 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02190:Gcn1
|
APN |
5 |
115,752,183 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02219:Gcn1
|
APN |
5 |
115,751,826 (GRCm39) |
missense |
possibly damaging |
0.68 |
|
IGL02507:Gcn1
|
APN |
5 |
115,723,940 (GRCm39) |
missense |
probably benign |
0.11 |
|
IGL02644:Gcn1
|
APN |
5 |
115,713,250 (GRCm39) |
missense |
probably benign |
|
|
IGL02678:Gcn1
|
APN |
5 |
115,751,814 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL02748:Gcn1
|
APN |
5 |
115,748,859 (GRCm39) |
splice site |
probably null |
|
|
IGL02755:Gcn1
|
APN |
5 |
115,742,065 (GRCm39) |
splice site |
probably null |
|
|
IGL02896:Gcn1
|
APN |
5 |
115,757,707 (GRCm39) |
splice site |
probably benign |
|
|
cusp
|
UTSW |
5 |
115,749,119 (GRCm39) |
missense |
probably damaging |
1.00 |
|
farthing
|
UTSW |
5 |
115,714,167 (GRCm39) |
splice site |
probably benign |
|
|
IGL03147:Gcn1
|
UTSW |
5 |
115,748,917 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
R0362:Gcn1
|
UTSW |
5 |
115,714,167 (GRCm39) |
splice site |
probably benign |
|
|
R0540:Gcn1
|
UTSW |
5 |
115,727,015 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0569:Gcn1
|
UTSW |
5 |
115,733,118 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0570:Gcn1
|
UTSW |
5 |
115,730,480 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0584:Gcn1
|
UTSW |
5 |
115,733,074 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0630:Gcn1
|
UTSW |
5 |
115,719,148 (GRCm39) |
missense |
probably benign |
0.06 |
|
R0656:Gcn1
|
UTSW |
5 |
115,727,362 (GRCm39) |
missense |
probably benign |
0.27 |
|
R0801:Gcn1
|
UTSW |
5 |
115,729,065 (GRCm39) |
missense |
probably benign |
0.12 |
|
R0890:Gcn1
|
UTSW |
5 |
115,717,852 (GRCm39) |
missense |
possibly damaging |
0.77 |
|
R1400:Gcn1
|
UTSW |
5 |
115,752,220 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1485:Gcn1
|
UTSW |
5 |
115,712,676 (GRCm39) |
missense |
probably benign |
|
|
R1574:Gcn1
|
UTSW |
5 |
115,753,611 (GRCm39) |
missense |
probably benign |
|
|
R1574:Gcn1
|
UTSW |
5 |
115,753,611 (GRCm39) |
missense |
probably benign |
|
|
R1673:Gcn1
|
UTSW |
5 |
115,720,356 (GRCm39) |
missense |
probably benign |
|
|
R1894:Gcn1
|
UTSW |
5 |
115,727,174 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2114:Gcn1
|
UTSW |
5 |
115,736,884 (GRCm39) |
missense |
probably benign |
0.35 |
|
R2117:Gcn1
|
UTSW |
5 |
115,736,884 (GRCm39) |
missense |
probably benign |
0.35 |
|
R2152:Gcn1
|
UTSW |
5 |
115,747,888 (GRCm39) |
missense |
probably benign |
0.07 |
|
R2162:Gcn1
|
UTSW |
5 |
115,730,191 (GRCm39) |
missense |
probably benign |
0.18 |
|
R2216:Gcn1
|
UTSW |
5 |
115,731,720 (GRCm39) |
missense |
probably benign |
|
|
R2218:Gcn1
|
UTSW |
5 |
115,757,720 (GRCm39) |
missense |
probably benign |
0.04 |
|
R2278:Gcn1
|
UTSW |
5 |
115,749,234 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2280:Gcn1
|
UTSW |
5 |
115,750,789 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3719:Gcn1
|
UTSW |
5 |
115,717,876 (GRCm39) |
missense |
probably benign |
0.03 |
|
R3729:Gcn1
|
UTSW |
5 |
115,721,453 (GRCm39) |
splice site |
probably benign |
|
|
R3833:Gcn1
|
UTSW |
5 |
115,730,191 (GRCm39) |
missense |
probably benign |
0.18 |
|
R3932:Gcn1
|
UTSW |
5 |
115,725,893 (GRCm39) |
missense |
probably benign |
0.11 |
|
R4067:Gcn1
|
UTSW |
5 |
115,737,147 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4152:Gcn1
|
UTSW |
5 |
115,751,413 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R4179:Gcn1
|
UTSW |
5 |
115,726,109 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4292:Gcn1
|
UTSW |
5 |
115,714,207 (GRCm39) |
missense |
possibly damaging |
0.49 |
|
R4350:Gcn1
|
UTSW |
5 |
115,741,389 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4493:Gcn1
|
UTSW |
5 |
115,732,203 (GRCm39) |
missense |
probably benign |
|
|
R4672:Gcn1
|
UTSW |
5 |
115,744,579 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4749:Gcn1
|
UTSW |
5 |
115,752,461 (GRCm39) |
missense |
probably benign |
|
|
R4753:Gcn1
|
UTSW |
5 |
115,754,537 (GRCm39) |
missense |
probably benign |
|
|
R4826:Gcn1
|
UTSW |
5 |
115,731,752 (GRCm39) |
missense |
probably benign |
|
|
R4873:Gcn1
|
UTSW |
5 |
115,714,229 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R4875:Gcn1
|
UTSW |
5 |
115,714,229 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R4932:Gcn1
|
UTSW |
5 |
115,730,203 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4992:Gcn1
|
UTSW |
5 |
115,737,225 (GRCm39) |
missense |
probably benign |
0.29 |
|
R5049:Gcn1
|
UTSW |
5 |
115,744,730 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5211:Gcn1
|
UTSW |
5 |
115,757,371 (GRCm39) |
missense |
probably benign |
0.04 |
|
R5226:Gcn1
|
UTSW |
5 |
115,726,126 (GRCm39) |
missense |
probably benign |
0.01 |
|
R5338:Gcn1
|
UTSW |
5 |
115,721,462 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5914:Gcn1
|
UTSW |
5 |
115,748,194 (GRCm39) |
synonymous |
silent |
|
|
R5932:Gcn1
|
UTSW |
5 |
115,730,435 (GRCm39) |
missense |
possibly damaging |
0.77 |
|
R6422:Gcn1
|
UTSW |
5 |
115,747,603 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6435:Gcn1
|
UTSW |
5 |
115,749,081 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R6607:Gcn1
|
UTSW |
5 |
115,747,537 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R6724:Gcn1
|
UTSW |
5 |
115,747,217 (GRCm39) |
splice site |
probably null |
|
|
R6861:Gcn1
|
UTSW |
5 |
115,749,108 (GRCm39) |
missense |
probably benign |
|
|
R6875:Gcn1
|
UTSW |
5 |
115,726,169 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6910:Gcn1
|
UTSW |
5 |
115,744,597 (GRCm39) |
missense |
probably benign |
0.42 |
|
R6975:Gcn1
|
UTSW |
5 |
115,751,518 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7027:Gcn1
|
UTSW |
5 |
115,754,605 (GRCm39) |
critical splice donor site |
probably null |
|
|
R7038:Gcn1
|
UTSW |
5 |
115,749,203 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7171:Gcn1
|
UTSW |
5 |
115,728,352 (GRCm39) |
missense |
probably benign |
0.02 |
|
R7276:Gcn1
|
UTSW |
5 |
115,749,119 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7456:Gcn1
|
UTSW |
5 |
115,743,005 (GRCm39) |
nonsense |
probably null |
|
|
R7473:Gcn1
|
UTSW |
5 |
115,719,863 (GRCm39) |
missense |
probably benign |
0.09 |
|
R7517:Gcn1
|
UTSW |
5 |
115,757,755 (GRCm39) |
missense |
probably benign |
0.01 |
|
R7714:Gcn1
|
UTSW |
5 |
115,733,359 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R7752:Gcn1
|
UTSW |
5 |
115,753,627 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7812:Gcn1
|
UTSW |
5 |
115,731,751 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R7922:Gcn1
|
UTSW |
5 |
115,752,527 (GRCm39) |
missense |
probably benign |
|
|
R8070:Gcn1
|
UTSW |
5 |
115,727,057 (GRCm39) |
missense |
probably benign |
0.09 |
|
R8218:Gcn1
|
UTSW |
5 |
115,719,588 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8329:Gcn1
|
UTSW |
5 |
115,747,921 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8413:Gcn1
|
UTSW |
5 |
115,717,698 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8795:Gcn1
|
UTSW |
5 |
115,752,454 (GRCm39) |
missense |
probably benign |
0.02 |
|
R8802:Gcn1
|
UTSW |
5 |
115,747,942 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8899:Gcn1
|
UTSW |
5 |
115,717,220 (GRCm39) |
missense |
probably benign |
0.04 |
|
R8946:Gcn1
|
UTSW |
5 |
115,733,404 (GRCm39) |
missense |
probably benign |
0.02 |
|
R8963:Gcn1
|
UTSW |
5 |
115,727,153 (GRCm39) |
missense |
probably benign |
0.25 |
|
R9006:Gcn1
|
UTSW |
5 |
115,719,566 (GRCm39) |
missense |
probably benign |
0.22 |
|
R9163:Gcn1
|
UTSW |
5 |
115,742,944 (GRCm39) |
missense |
probably benign |
|
|
R9177:Gcn1
|
UTSW |
5 |
115,719,867 (GRCm39) |
missense |
probably benign |
0.35 |
|
R9187:Gcn1
|
UTSW |
5 |
115,752,177 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9411:Gcn1
|
UTSW |
5 |
115,733,098 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
R9541:Gcn1
|
UTSW |
5 |
115,754,416 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9574:Gcn1
|
UTSW |
5 |
115,713,341 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R9630:Gcn1
|
UTSW |
5 |
115,741,349 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9651:Gcn1
|
UTSW |
5 |
115,747,665 (GRCm39) |
critical splice donor site |
probably null |
|
|
R9761:Gcn1
|
UTSW |
5 |
115,729,064 (GRCm39) |
missense |
probably benign |
0.05 |
|
R9765:Gcn1
|
UTSW |
5 |
115,735,131 (GRCm39) |
nonsense |
probably null |
|
|
Z1177:Gcn1
|
UTSW |
5 |
115,752,208 (GRCm39) |
missense |
probably damaging |
0.99 |
|
Z1191:Gcn1
|
UTSW |
5 |
115,713,352 (GRCm39) |
missense |
possibly damaging |
0.76 |
|
| Predicted Primers |
PCR Primer
(F):5'- AATTGTCCTCCTTCCACATGGG -3'
(R):5'- CAGCAGTGAGTTGACATTCTCC -3'
Sequencing Primer
(F):5'- CTTCCACATGGGGCGCC -3'
(R):5'- AGTTGACATTCTCCTGCGAAG -3'
|
| Posted On |
2014-09-18 |
Incidental Mutation