Incidental Mutation 'R2152:Gcn1'
| ID |
234372 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Gcn1
|
| Ensembl Gene |
ENSMUSG00000041638 |
| Gene Name |
GCN1 activator of EIF2AK4 |
| Synonyms |
Gcn1l1, G431004K08Rik, GCN1L |
| MMRRC Submission |
040155-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably essential
(E-score: 0.948)
|
| Stock # |
R2152 (G1)
|
| Quality Score |
225 |
|
Status
|
Not validated
|
| Chromosome |
5 |
| Chromosomal Location |
115703313-115760713 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to A
at 115747888 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Isoleucine to Asparagine
at position 1765
(I1765N)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000069432
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000064454]
|
| AlphaFold |
E9PVA8 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000064454
AA Change: I1765N
PolyPhen 2
Score 0.071 (Sensitivity: 0.94; Specificity: 0.84)
|
| SMART Domains |
Protein: ENSMUSP00000069432
Gene: ENSMUSG00000041638
AA Change: I1765N
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
64 |
84 |
N/A |
INTRINSIC |
|
low complexity region
|
108 |
117 |
N/A |
INTRINSIC |
|
low complexity region
|
142 |
154 |
N/A |
INTRINSIC |
|
Pfam:DUF3554
|
357 |
705 |
2e-61 |
PFAM |
|
coiled coil region
|
806 |
866 |
N/A |
INTRINSIC |
|
Blast:ARM
|
1028 |
1068 |
6e-11 |
BLAST |
|
coiled coil region
|
1180 |
1203 |
N/A |
INTRINSIC |
|
low complexity region
|
1457 |
1466 |
N/A |
INTRINSIC |
|
low complexity region
|
1501 |
1510 |
N/A |
INTRINSIC |
|
ARM
|
1527 |
1567 |
3.69e1 |
SMART |
|
Blast:ARM
|
1602 |
1644 |
1e-5 |
BLAST |
|
Blast:EZ_HEAT
|
1671 |
1704 |
1e-7 |
BLAST |
|
low complexity region
|
1926 |
1934 |
N/A |
INTRINSIC |
|
low complexity region
|
1956 |
1972 |
N/A |
INTRINSIC |
|
ARM
|
2034 |
2070 |
9.27e1 |
SMART |
|
low complexity region
|
2326 |
2334 |
N/A |
INTRINSIC |
|
ARM
|
2416 |
2455 |
2.16e1 |
SMART |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000094427
|
| SMART Domains |
Protein: ENSMUSP00000091994
Gene: ENSMUSG00000041638
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:HEAT
|
42 |
72 |
5.8e-5 |
PFAM |
|
low complexity region
|
310 |
318 |
N/A |
INTRINSIC |
|
Pfam:HEAT_EZ
|
326 |
374 |
2.2e-5 |
PFAM |
|
Blast:EZ_HEAT
|
403 |
439 |
1e-15 |
BLAST |
|
Pfam:HEAT_EZ
|
703 |
757 |
1.3e-5 |
PFAM |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000122964
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000139933
|
| Coding Region Coverage |
- 1x: 99.2%
- 3x: 98.6%
- 10x: 97.4%
- 20x: 95.4%
|
| Validation Efficiency |
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 108 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Ackr3 |
A |
T |
1: 90,141,565 (GRCm39) |
Y8F |
probably benign |
Het |
| Acy1 |
T |
C |
9: 106,312,816 (GRCm39) |
E175G |
probably damaging |
Het |
| Add2 |
T |
C |
6: 86,075,580 (GRCm39) |
L243P |
probably damaging |
Het |
| Adsl |
A |
G |
15: 80,851,863 (GRCm39) |
D407G |
probably damaging |
Het |
| Afg3l1 |
T |
G |
8: 124,221,575 (GRCm39) |
I478S |
probably damaging |
Het |
| Aoc1l1 |
T |
A |
6: 48,953,473 (GRCm39) |
I466N |
probably damaging |
Het |
| Arfrp1 |
T |
C |
2: 181,001,487 (GRCm39) |
T108A |
probably benign |
Het |
| Art5 |
A |
G |
7: 101,747,407 (GRCm39) |
L124P |
possibly damaging |
Het |
| Asap2 |
A |
T |
12: 21,162,084 (GRCm39) |
T14S |
probably damaging |
Het |
| Atp2c2 |
A |
G |
8: 120,482,841 (GRCm39) |
N901S |
probably benign |
Het |
| Bbs12 |
G |
T |
3: 37,375,309 (GRCm39) |
E586* |
probably null |
Het |
| Bicd2 |
G |
T |
13: 49,533,052 (GRCm39) |
C546F |
probably damaging |
Het |
| Bid |
A |
T |
6: 120,877,215 (GRCm39) |
L42Q |
probably damaging |
Het |
| Bpifb9a |
A |
G |
2: 154,102,055 (GRCm39) |
K51E |
probably benign |
Het |
| Calcr |
G |
T |
6: 3,687,615 (GRCm39) |
T424K |
probably benign |
Het |
| Cd46 |
A |
G |
1: 194,744,721 (GRCm39) |
I339T |
probably benign |
Het |
| Chek1 |
C |
A |
9: 36,635,279 (GRCm39) |
V35F |
probably damaging |
Het |
| Cntn3 |
A |
G |
6: 102,183,498 (GRCm39) |
I719T |
probably damaging |
Het |
| Cyb5r1 |
T |
C |
1: 134,337,363 (GRCm39) |
I163T |
possibly damaging |
Het |
| Cyp2d26 |
A |
T |
15: 82,676,907 (GRCm39) |
|
probably null |
Het |
| Dclk1 |
A |
G |
3: 55,154,633 (GRCm39) |
Y21C |
probably damaging |
Het |
| Dgcr2 |
G |
A |
16: 17,709,351 (GRCm39) |
|
probably null |
Het |
| Dhx38 |
T |
C |
8: 110,287,306 (GRCm39) |
S221G |
probably benign |
Het |
| Dis3l |
T |
A |
9: 64,214,545 (GRCm39) |
N981I |
probably benign |
Het |
| Dnah3 |
C |
T |
7: 119,551,236 (GRCm39) |
V3028I |
probably benign |
Het |
| Dnah6 |
T |
C |
6: 73,026,149 (GRCm39) |
Y3448C |
probably benign |
Het |
| Dok5 |
G |
A |
2: 170,642,816 (GRCm39) |
G38D |
probably damaging |
Het |
| Epb41l1 |
A |
G |
2: 156,356,048 (GRCm39) |
D528G |
probably damaging |
Het |
| Fat4 |
A |
T |
3: 39,037,544 (GRCm39) |
Y3732F |
probably damaging |
Het |
| Fcsk |
T |
A |
8: 111,615,704 (GRCm39) |
T542S |
probably benign |
Het |
| Fgfr4 |
A |
T |
13: 55,314,777 (GRCm39) |
Y640F |
probably damaging |
Het |
| Foxo6 |
T |
A |
4: 120,125,811 (GRCm39) |
D328V |
probably benign |
Het |
| Foxp1 |
A |
G |
6: 98,993,502 (GRCm39) |
L134P |
probably damaging |
Het |
| Frem2 |
G |
A |
3: 53,424,450 (GRCm39) |
R2996* |
probably null |
Het |
| Garem2 |
T |
C |
5: 30,313,297 (GRCm39) |
S54P |
probably damaging |
Het |
| Gm4787 |
T |
A |
12: 81,423,993 (GRCm39) |
I722F |
probably benign |
Het |
| Gpc6 |
G |
T |
14: 117,163,504 (GRCm39) |
A53S |
probably benign |
Het |
| Gtpbp8 |
A |
G |
16: 44,560,390 (GRCm39) |
|
probably null |
Het |
| H2-Q2 |
T |
C |
17: 35,564,252 (GRCm39) |
|
probably null |
Het |
| Hapln2 |
C |
A |
3: 87,930,920 (GRCm39) |
R157L |
probably benign |
Het |
| Hemgn |
C |
A |
4: 46,396,607 (GRCm39) |
E210* |
probably null |
Het |
| Hpse |
T |
A |
5: 100,839,269 (GRCm39) |
K360* |
probably null |
Het |
| Iqcj |
A |
T |
3: 67,962,643 (GRCm39) |
E68V |
probably damaging |
Het |
| Kat2a |
T |
C |
11: 100,603,172 (GRCm39) |
|
probably benign |
Het |
| Kat6b |
A |
T |
14: 21,718,735 (GRCm39) |
H1138L |
probably benign |
Het |
| Kcnab1 |
A |
T |
3: 65,278,861 (GRCm39) |
I371F |
probably damaging |
Het |
| Klhl30 |
C |
A |
1: 91,285,546 (GRCm39) |
A356D |
probably benign |
Het |
| Klra3 |
G |
C |
6: 130,310,107 (GRCm39) |
R138G |
probably benign |
Het |
| Micu1 |
G |
T |
10: 59,699,110 (GRCm39) |
M468I |
probably benign |
Het |
| Mrc1 |
A |
G |
2: 14,332,675 (GRCm39) |
T1292A |
probably damaging |
Het |
| Myh8 |
G |
A |
11: 67,185,295 (GRCm39) |
E849K |
probably damaging |
Het |
| Myom3 |
G |
T |
4: 135,530,544 (GRCm39) |
R1152L |
probably benign |
Het |
| Nedd4l |
T |
A |
18: 65,343,401 (GRCm39) |
H820Q |
probably damaging |
Het |
| Nlrp4g |
T |
A |
9: 124,353,339 (GRCm38) |
|
noncoding transcript |
Het |
| Oga |
A |
T |
19: 45,746,461 (GRCm39) |
Y779* |
probably null |
Het |
| Or13p5 |
C |
T |
4: 118,592,446 (GRCm39) |
A240V |
possibly damaging |
Het |
| Or1m1 |
T |
C |
9: 18,666,391 (GRCm39) |
D180G |
probably damaging |
Het |
| Or2a51 |
A |
G |
6: 43,179,003 (GRCm39) |
I142V |
probably benign |
Het |
| Or51a39 |
G |
T |
7: 102,362,788 (GRCm39) |
H277Q |
probably benign |
Het |
| Or52j3 |
A |
T |
7: 102,835,847 (GRCm39) |
D13V |
probably benign |
Het |
| Or8b49 |
G |
T |
9: 38,505,707 (GRCm39) |
L63F |
probably damaging |
Het |
| Or8g54 |
A |
T |
9: 39,706,943 (GRCm39) |
I91F |
probably benign |
Het |
| Or9s23 |
T |
C |
1: 92,501,630 (GRCm39) |
S246P |
probably damaging |
Het |
| Otop1 |
T |
A |
5: 38,460,194 (GRCm39) |
M587K |
probably damaging |
Het |
| Pgm5 |
T |
A |
19: 24,812,179 (GRCm39) |
I118F |
probably damaging |
Het |
| Phc2 |
A |
G |
4: 128,638,859 (GRCm39) |
*41W |
probably null |
Het |
| Phf8-ps |
T |
A |
17: 33,285,908 (GRCm39) |
D298V |
probably damaging |
Het |
| Piezo2 |
A |
T |
18: 63,247,112 (GRCm39) |
M532K |
probably damaging |
Het |
| Pjvk |
A |
T |
2: 76,488,713 (GRCm39) |
I295F |
probably benign |
Het |
| Popdc2 |
A |
G |
16: 38,183,482 (GRCm39) |
N155S |
possibly damaging |
Het |
| Ppp4r3a |
G |
T |
12: 101,008,826 (GRCm39) |
N684K |
probably damaging |
Het |
| Prpf4b |
T |
A |
13: 35,084,402 (GRCm39) |
M930K |
probably benign |
Het |
| Ptpn12 |
C |
A |
5: 21,207,466 (GRCm39) |
Q297H |
probably damaging |
Het |
| Ptprz1 |
C |
A |
6: 23,030,670 (GRCm39) |
L1010I |
probably damaging |
Het |
| Rabepk |
A |
T |
2: 34,674,562 (GRCm39) |
D232E |
possibly damaging |
Het |
| Rad51ap2 |
A |
G |
12: 11,507,986 (GRCm39) |
H636R |
probably benign |
Het |
| Rb1 |
T |
C |
14: 73,526,165 (GRCm39) |
T169A |
probably benign |
Het |
| Rcc2 |
T |
C |
4: 140,444,428 (GRCm39) |
L373P |
probably damaging |
Het |
| Rif1 |
GCCACCA |
GCCA |
2: 52,000,336 (GRCm39) |
|
probably benign |
Het |
| Rrbp1 |
A |
G |
2: 143,796,118 (GRCm39) |
L1200P |
possibly damaging |
Het |
| Sdk1 |
A |
G |
5: 141,778,699 (GRCm39) |
N226D |
probably damaging |
Het |
| Selenbp1 |
G |
A |
3: 94,851,441 (GRCm39) |
R398H |
probably damaging |
Het |
| Selenoo |
A |
G |
15: 88,983,485 (GRCm39) |
M509V |
probably benign |
Het |
| Sidt2 |
T |
C |
9: 45,856,638 (GRCm39) |
D477G |
probably damaging |
Het |
| Slc2a5 |
T |
G |
4: 150,210,095 (GRCm39) |
S27A |
probably damaging |
Het |
| Slc30a5 |
A |
T |
13: 100,940,457 (GRCm39) |
H619Q |
probably damaging |
Het |
| Slc5a9 |
A |
G |
4: 111,750,420 (GRCm39) |
I146T |
possibly damaging |
Het |
| Slc6a1 |
G |
T |
6: 114,284,731 (GRCm39) |
G263V |
probably damaging |
Het |
| Slmap |
A |
G |
14: 26,139,402 (GRCm39) |
Y771H |
probably damaging |
Het |
| Snx29 |
A |
G |
16: 11,218,707 (GRCm39) |
D181G |
possibly damaging |
Het |
| Spata31d1c |
G |
A |
13: 65,181,779 (GRCm39) |
|
probably null |
Het |
| Stat5a |
C |
A |
11: 100,764,916 (GRCm39) |
T213N |
probably benign |
Het |
| Stt3a |
A |
T |
9: 36,659,292 (GRCm39) |
V349D |
probably damaging |
Het |
| Tcf20 |
A |
T |
15: 82,739,803 (GRCm39) |
D549E |
probably damaging |
Het |
| Thbs2 |
T |
A |
17: 14,893,471 (GRCm39) |
D903V |
probably damaging |
Het |
| Tln2 |
T |
C |
9: 67,209,842 (GRCm39) |
T432A |
probably damaging |
Het |
| Tmc1 |
A |
T |
19: 20,834,039 (GRCm39) |
N241K |
probably benign |
Het |
| Tmem260 |
G |
T |
14: 48,715,066 (GRCm39) |
R240L |
possibly damaging |
Het |
| Tnfaip6 |
A |
T |
2: 51,933,742 (GRCm39) |
E32D |
probably damaging |
Het |
| Trpa1 |
A |
T |
1: 14,969,625 (GRCm39) |
H381Q |
probably damaging |
Het |
| Tsen2 |
T |
C |
6: 115,524,936 (GRCm39) |
I45T |
possibly damaging |
Het |
| Ttc6 |
G |
A |
12: 57,752,338 (GRCm39) |
V1415I |
probably damaging |
Het |
| Ttll7 |
G |
T |
3: 146,635,944 (GRCm39) |
R426L |
probably damaging |
Het |
| Ttn |
A |
C |
2: 76,570,482 (GRCm39) |
S26804A |
probably damaging |
Het |
| Ubqlnl |
A |
T |
7: 103,797,890 (GRCm39) |
C536S |
probably benign |
Het |
| Vmn2r73 |
A |
G |
7: 85,506,936 (GRCm39) |
V792A |
probably benign |
Het |
| Zfp345 |
T |
C |
2: 150,314,578 (GRCm39) |
T320A |
probably benign |
Het |
| Zfp407 |
T |
C |
18: 84,227,774 (GRCm39) |
D1945G |
possibly damaging |
Het |
|
| Other mutations in Gcn1 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00869:Gcn1
|
APN |
5 |
115,726,202 (GRCm39) |
splice site |
probably benign |
|
|
IGL00974:Gcn1
|
APN |
5 |
115,751,852 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
IGL01566:Gcn1
|
APN |
5 |
115,749,117 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01843:Gcn1
|
APN |
5 |
115,757,759 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01885:Gcn1
|
APN |
5 |
115,714,174 (GRCm39) |
splice site |
probably null |
|
|
IGL02081:Gcn1
|
APN |
5 |
115,723,930 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02118:Gcn1
|
APN |
5 |
115,748,938 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02150:Gcn1
|
APN |
5 |
115,747,927 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02190:Gcn1
|
APN |
5 |
115,752,183 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02219:Gcn1
|
APN |
5 |
115,751,826 (GRCm39) |
missense |
possibly damaging |
0.68 |
|
IGL02507:Gcn1
|
APN |
5 |
115,723,940 (GRCm39) |
missense |
probably benign |
0.11 |
|
IGL02644:Gcn1
|
APN |
5 |
115,713,250 (GRCm39) |
missense |
probably benign |
|
|
IGL02678:Gcn1
|
APN |
5 |
115,751,814 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL02748:Gcn1
|
APN |
5 |
115,748,859 (GRCm39) |
splice site |
probably null |
|
|
IGL02755:Gcn1
|
APN |
5 |
115,742,065 (GRCm39) |
splice site |
probably null |
|
|
IGL02896:Gcn1
|
APN |
5 |
115,757,707 (GRCm39) |
splice site |
probably benign |
|
|
cusp
|
UTSW |
5 |
115,749,119 (GRCm39) |
missense |
probably damaging |
1.00 |
|
farthing
|
UTSW |
5 |
115,714,167 (GRCm39) |
splice site |
probably benign |
|
|
IGL03147:Gcn1
|
UTSW |
5 |
115,748,917 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
R0362:Gcn1
|
UTSW |
5 |
115,714,167 (GRCm39) |
splice site |
probably benign |
|
|
R0540:Gcn1
|
UTSW |
5 |
115,727,015 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0569:Gcn1
|
UTSW |
5 |
115,733,118 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0570:Gcn1
|
UTSW |
5 |
115,730,480 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0584:Gcn1
|
UTSW |
5 |
115,733,074 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0630:Gcn1
|
UTSW |
5 |
115,719,148 (GRCm39) |
missense |
probably benign |
0.06 |
|
R0656:Gcn1
|
UTSW |
5 |
115,727,362 (GRCm39) |
missense |
probably benign |
0.27 |
|
R0801:Gcn1
|
UTSW |
5 |
115,729,065 (GRCm39) |
missense |
probably benign |
0.12 |
|
R0890:Gcn1
|
UTSW |
5 |
115,717,852 (GRCm39) |
missense |
possibly damaging |
0.77 |
|
R1400:Gcn1
|
UTSW |
5 |
115,752,220 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1485:Gcn1
|
UTSW |
5 |
115,712,676 (GRCm39) |
missense |
probably benign |
|
|
R1574:Gcn1
|
UTSW |
5 |
115,753,611 (GRCm39) |
missense |
probably benign |
|
|
R1574:Gcn1
|
UTSW |
5 |
115,753,611 (GRCm39) |
missense |
probably benign |
|
|
R1673:Gcn1
|
UTSW |
5 |
115,720,356 (GRCm39) |
missense |
probably benign |
|
|
R1894:Gcn1
|
UTSW |
5 |
115,727,174 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2114:Gcn1
|
UTSW |
5 |
115,736,884 (GRCm39) |
missense |
probably benign |
0.35 |
|
R2116:Gcn1
|
UTSW |
5 |
115,736,884 (GRCm39) |
missense |
probably benign |
0.35 |
|
R2117:Gcn1
|
UTSW |
5 |
115,736,884 (GRCm39) |
missense |
probably benign |
0.35 |
|
R2162:Gcn1
|
UTSW |
5 |
115,730,191 (GRCm39) |
missense |
probably benign |
0.18 |
|
R2216:Gcn1
|
UTSW |
5 |
115,731,720 (GRCm39) |
missense |
probably benign |
|
|
R2218:Gcn1
|
UTSW |
5 |
115,757,720 (GRCm39) |
missense |
probably benign |
0.04 |
|
R2278:Gcn1
|
UTSW |
5 |
115,749,234 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2280:Gcn1
|
UTSW |
5 |
115,750,789 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3719:Gcn1
|
UTSW |
5 |
115,717,876 (GRCm39) |
missense |
probably benign |
0.03 |
|
R3729:Gcn1
|
UTSW |
5 |
115,721,453 (GRCm39) |
splice site |
probably benign |
|
|
R3833:Gcn1
|
UTSW |
5 |
115,730,191 (GRCm39) |
missense |
probably benign |
0.18 |
|
R3932:Gcn1
|
UTSW |
5 |
115,725,893 (GRCm39) |
missense |
probably benign |
0.11 |
|
R4067:Gcn1
|
UTSW |
5 |
115,737,147 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4152:Gcn1
|
UTSW |
5 |
115,751,413 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R4179:Gcn1
|
UTSW |
5 |
115,726,109 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4292:Gcn1
|
UTSW |
5 |
115,714,207 (GRCm39) |
missense |
possibly damaging |
0.49 |
|
R4350:Gcn1
|
UTSW |
5 |
115,741,389 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4493:Gcn1
|
UTSW |
5 |
115,732,203 (GRCm39) |
missense |
probably benign |
|
|
R4672:Gcn1
|
UTSW |
5 |
115,744,579 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4749:Gcn1
|
UTSW |
5 |
115,752,461 (GRCm39) |
missense |
probably benign |
|
|
R4753:Gcn1
|
UTSW |
5 |
115,754,537 (GRCm39) |
missense |
probably benign |
|
|
R4826:Gcn1
|
UTSW |
5 |
115,731,752 (GRCm39) |
missense |
probably benign |
|
|
R4873:Gcn1
|
UTSW |
5 |
115,714,229 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R4875:Gcn1
|
UTSW |
5 |
115,714,229 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R4932:Gcn1
|
UTSW |
5 |
115,730,203 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4992:Gcn1
|
UTSW |
5 |
115,737,225 (GRCm39) |
missense |
probably benign |
0.29 |
|
R5049:Gcn1
|
UTSW |
5 |
115,744,730 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5211:Gcn1
|
UTSW |
5 |
115,757,371 (GRCm39) |
missense |
probably benign |
0.04 |
|
R5226:Gcn1
|
UTSW |
5 |
115,726,126 (GRCm39) |
missense |
probably benign |
0.01 |
|
R5338:Gcn1
|
UTSW |
5 |
115,721,462 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5914:Gcn1
|
UTSW |
5 |
115,748,194 (GRCm39) |
synonymous |
silent |
|
|
R5932:Gcn1
|
UTSW |
5 |
115,730,435 (GRCm39) |
missense |
possibly damaging |
0.77 |
|
R6422:Gcn1
|
UTSW |
5 |
115,747,603 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6435:Gcn1
|
UTSW |
5 |
115,749,081 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R6607:Gcn1
|
UTSW |
5 |
115,747,537 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R6724:Gcn1
|
UTSW |
5 |
115,747,217 (GRCm39) |
splice site |
probably null |
|
|
R6861:Gcn1
|
UTSW |
5 |
115,749,108 (GRCm39) |
missense |
probably benign |
|
|
R6875:Gcn1
|
UTSW |
5 |
115,726,169 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6910:Gcn1
|
UTSW |
5 |
115,744,597 (GRCm39) |
missense |
probably benign |
0.42 |
|
R6975:Gcn1
|
UTSW |
5 |
115,751,518 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7027:Gcn1
|
UTSW |
5 |
115,754,605 (GRCm39) |
critical splice donor site |
probably null |
|
|
R7038:Gcn1
|
UTSW |
5 |
115,749,203 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7171:Gcn1
|
UTSW |
5 |
115,728,352 (GRCm39) |
missense |
probably benign |
0.02 |
|
R7276:Gcn1
|
UTSW |
5 |
115,749,119 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7456:Gcn1
|
UTSW |
5 |
115,743,005 (GRCm39) |
nonsense |
probably null |
|
|
R7473:Gcn1
|
UTSW |
5 |
115,719,863 (GRCm39) |
missense |
probably benign |
0.09 |
|
R7517:Gcn1
|
UTSW |
5 |
115,757,755 (GRCm39) |
missense |
probably benign |
0.01 |
|
R7714:Gcn1
|
UTSW |
5 |
115,733,359 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R7752:Gcn1
|
UTSW |
5 |
115,753,627 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7812:Gcn1
|
UTSW |
5 |
115,731,751 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R7922:Gcn1
|
UTSW |
5 |
115,752,527 (GRCm39) |
missense |
probably benign |
|
|
R8070:Gcn1
|
UTSW |
5 |
115,727,057 (GRCm39) |
missense |
probably benign |
0.09 |
|
R8218:Gcn1
|
UTSW |
5 |
115,719,588 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8329:Gcn1
|
UTSW |
5 |
115,747,921 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8413:Gcn1
|
UTSW |
5 |
115,717,698 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8795:Gcn1
|
UTSW |
5 |
115,752,454 (GRCm39) |
missense |
probably benign |
0.02 |
|
R8802:Gcn1
|
UTSW |
5 |
115,747,942 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8899:Gcn1
|
UTSW |
5 |
115,717,220 (GRCm39) |
missense |
probably benign |
0.04 |
|
R8946:Gcn1
|
UTSW |
5 |
115,733,404 (GRCm39) |
missense |
probably benign |
0.02 |
|
R8963:Gcn1
|
UTSW |
5 |
115,727,153 (GRCm39) |
missense |
probably benign |
0.25 |
|
R9006:Gcn1
|
UTSW |
5 |
115,719,566 (GRCm39) |
missense |
probably benign |
0.22 |
|
R9163:Gcn1
|
UTSW |
5 |
115,742,944 (GRCm39) |
missense |
probably benign |
|
|
R9177:Gcn1
|
UTSW |
5 |
115,719,867 (GRCm39) |
missense |
probably benign |
0.35 |
|
R9187:Gcn1
|
UTSW |
5 |
115,752,177 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9411:Gcn1
|
UTSW |
5 |
115,733,098 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
R9541:Gcn1
|
UTSW |
5 |
115,754,416 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9574:Gcn1
|
UTSW |
5 |
115,713,341 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R9630:Gcn1
|
UTSW |
5 |
115,741,349 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9651:Gcn1
|
UTSW |
5 |
115,747,665 (GRCm39) |
critical splice donor site |
probably null |
|
|
R9761:Gcn1
|
UTSW |
5 |
115,729,064 (GRCm39) |
missense |
probably benign |
0.05 |
|
R9765:Gcn1
|
UTSW |
5 |
115,735,131 (GRCm39) |
nonsense |
probably null |
|
|
Z1177:Gcn1
|
UTSW |
5 |
115,752,208 (GRCm39) |
missense |
probably damaging |
0.99 |
|
Z1191:Gcn1
|
UTSW |
5 |
115,713,352 (GRCm39) |
missense |
possibly damaging |
0.76 |
|
| Predicted Primers |
PCR Primer
(F):5'- GTCCCATGGCTGATTCCATC -3'
(R):5'- TACATCGAGATGACCCGCTG -3'
Sequencing Primer
(F):5'- ATGGCTGATTCCATCCTTGC -3'
(R):5'- GTTCTCATCAGCCAGAGCCTAG -3'
|
| Posted On |
2014-10-01 |
Incidental Mutation