Mutagenetix > Incidental Mutation

Incidental Mutation 'R2155:Igsf10'

234689

Institutional Source

Beutler Lab

Gene Symbol

Igsf10

Ensembl Gene

ENSMUSG00000036334

Gene Name

immunoglobulin superfamily, member 10

Synonyms

6530405F15Rik, CMF608, Adlican2

MMRRC Submission

040158-MU

Accession Numbers

Essential gene?

Probably non essential (E-score: 0.193) question?

Stock #

R2155 (G1)

Quality Score

225

Status

Not validated

Chromosome

Chromosomal Location

59224156-59251815 bp(-) (GRCm39)

Type of Mutation

missense

DNA Base Change (assembly)

G to T at 59239101 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Threonine to Lysine at position 360 (T360K)

Ref Sequence

ENSEMBL: ENSMUSP00000141391 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000039419] [ENSMUST00000193455] [ENSMUST00000194546]

AlphaFold

Q3V1M1

Predicted Effect

probably damaging
Transcript: ENSMUST00000039419
AA Change: T360K

PolyPhen 2 Score 0.996 (Sensitivity: 0.55; Specificity: 0.98)

SMART Domains

Protein: ENSMUSP00000037246
Gene: ENSMUSG00000036334
AA Change: T360K

Domain	Start	End	E-Value	Type
signal peptide	1	25	N/A	INTRINSIC
LRRNT	28	61	3.24e-4	SMART
LRR	57	79	9.24e1	SMART
LRR	80	103	2.02e-1	SMART
LRR	104	127	7.16e0	SMART
LRR_TYP	128	151	1.2e-3	SMART
LRR	152	175	1.25e-1	SMART
LRR	188	207	2.33e2	SMART
LRRCT	219	280	4.19e-4	SMART
IGc2	488	558	2.34e-4	SMART
IGc2	586	652	7.88e-11	SMART
low complexity region	917	930	N/A	INTRINSIC
low complexity region	1175	1185	N/A	INTRINSIC
low complexity region	1245	1263	N/A	INTRINSIC
low complexity region	1311	1321	N/A	INTRINSIC
low complexity region	1449	1465	N/A	INTRINSIC
IGc2	1632	1701	7.69e-14	SMART
IGc2	1729	1798	5.07e-14	SMART
IGc2	1826	1895	2.19e-9	SMART
IGc2	1925	1994	4.59e-12	SMART
IGc2	2022	2097	1.33e-8	SMART
IGc2	2125	2191	2.96e-15	SMART
IGc2	2223	2291	2.03e-4	SMART
IGc2	2321	2389	9.99e-13	SMART
IGc2	2416	2484	3.03e-12	SMART
IGc2	2512	2583	7.76e-10	SMART

Predicted Effect

probably damaging
Transcript: ENSMUST00000193455
AA Change: T360K

PolyPhen 2 Score 0.996 (Sensitivity: 0.55; Specificity: 0.98)

SMART Domains

Protein: ENSMUSP00000141971
Gene: ENSMUSG00000036334
AA Change: T360K

Domain	Start	End	E-Value	Type
signal peptide	1	25	N/A	INTRINSIC
LRRNT	28	61	3.24e-4	SMART
LRR	57	79	9.24e1	SMART
LRR	80	103	2.02e-1	SMART
LRR	104	127	7.16e0	SMART
LRR_TYP	128	151	1.2e-3	SMART
LRR	152	175	1.25e-1	SMART
LRR	188	207	2.33e2	SMART
LRRCT	219	280	4.19e-4	SMART
IGc2	488	558	2.34e-4	SMART
IGc2	586	652	7.88e-11	SMART
low complexity region	917	930	N/A	INTRINSIC
low complexity region	1175	1185	N/A	INTRINSIC
low complexity region	1245	1263	N/A	INTRINSIC
low complexity region	1311	1321	N/A	INTRINSIC
low complexity region	1449	1465	N/A	INTRINSIC
IGc2	1632	1701	7.69e-14	SMART
IGc2	1729	1798	5.07e-14	SMART
IGc2	1826	1895	2.19e-9	SMART
IGc2	1925	1994	4.59e-12	SMART
IGc2	2022	2097	1.33e-8	SMART
IGc2	2125	2191	2.96e-15	SMART
IGc2	2223	2291	2.03e-4	SMART
IGc2	2321	2389	9.99e-13	SMART
IGc2	2416	2484	3.03e-12	SMART
IGc2	2512	2583	7.76e-10	SMART

Predicted Effect

probably damaging
Transcript: ENSMUST00000194546
AA Change: T360K

PolyPhen 2 Score 0.996 (Sensitivity: 0.55; Specificity: 0.98)

SMART Domains

Protein: ENSMUSP00000141391
Gene: ENSMUSG00000036334
AA Change: T360K

Domain	Start	End	E-Value	Type
signal peptide	1	25	N/A	INTRINSIC
LRRNT	28	61	3.24e-4	SMART
LRR	57	79	9.24e1	SMART
LRR	80	103	2.02e-1	SMART
LRR	104	127	7.16e0	SMART
LRR_TYP	128	151	1.2e-3	SMART
LRR	152	175	1.25e-1	SMART
LRR	188	207	2.33e2	SMART
LRRCT	219	280	4.19e-4	SMART
IGc2	488	558	2.34e-4	SMART
IGc2	586	652	7.88e-11	SMART
low complexity region	917	930	N/A	INTRINSIC
low complexity region	1175	1185	N/A	INTRINSIC
low complexity region	1245	1263	N/A	INTRINSIC
low complexity region	1311	1321	N/A	INTRINSIC
low complexity region	1449	1465	N/A	INTRINSIC
IGc2	1632	1701	7.69e-14	SMART
IGc2	1729	1798	5.07e-14	SMART
IGc2	1826	1895	2.19e-9	SMART
IGc2	1925	1994	4.59e-12	SMART
IGc2	2022	2097	1.33e-8	SMART
IGc2	2125	2191	2.96e-15	SMART
IGc2	2223	2291	2.03e-4	SMART
IGc2	2321	2389	9.99e-13	SMART
IGc2	2416	2484	3.03e-12	SMART
IGc2	2512	2583	7.76e-10	SMART

Coding Region Coverage

1x: 99.2%
3x: 98.6%
10x: 97.4%
20x: 95.4%

Validation Efficiency

Allele List at MGI

All alleles(2) : Targeted, other(2)

Other mutations in this stock

Total: 89 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
2610318N02Rik	A	G	16: 16,939,260 (GRCm39)	L41P	probably damaging	Het
Aff4	C	T	11: 53,290,446 (GRCm39)	L469F	probably damaging	Het
AI182371	G	A	2: 34,975,366 (GRCm39)	H288Y	probably benign	Het
AK157302	A	T	13: 21,679,827 (GRCm39)	K118*	probably null	Het
Arhgef2	G	A	3: 88,543,351 (GRCm39)	R454Q	probably damaging	Het
Asb17	C	T	3: 153,550,322 (GRCm39)	T118M	probably damaging	Het
Atp7b	A	G	8: 22,503,600 (GRCm39)	V718A	possibly damaging	Het
Cdca2	A	G	14: 67,952,287 (GRCm39)	L28S	probably damaging	Het
Cdh20	G	T	1: 109,976,594 (GRCm39)	L86F	probably damaging	Het
Cela2a	A	T	4: 141,545,350 (GRCm39)		probably null	Het
Cers3	T	A	7: 66,433,162 (GRCm39)	Y160N	probably damaging	Het
Chmp2b	A	G	16: 65,343,877 (GRCm39)	V56A	probably benign	Het
Cryl1	A	G	14: 57,635,880 (GRCm39)	V9A	unknown	Het
Dmbt1	A	T	7: 130,699,305 (GRCm39)	H978L	possibly damaging	Het
Dnm1	C	T	2: 32,204,949 (GRCm39)	V673M	probably damaging	Het
Dtx4	T	A	19: 12,462,646 (GRCm39)	K378*	probably null	Het
Extl1	A	T	4: 134,090,491 (GRCm39)	M328K	possibly damaging	Het
Fcgbp	T	C	7: 27,806,628 (GRCm39)	S2199P	probably benign	Het
Glis3	G	T	19: 28,508,702 (GRCm39)	N427K	probably benign	Het
Hdac7	T	C	15: 97,691,944 (GRCm39)	K810E	probably benign	Het
Hesx1	A	G	14: 26,723,434 (GRCm39)	E88G	probably benign	Het
Hmcn2	A	T	2: 31,350,361 (GRCm39)	Q5086L	possibly damaging	Het
Ier3	A	G	17: 36,133,101 (GRCm39)	T128A	probably benign	Het
Ilkap	A	C	1: 91,312,345 (GRCm39)	C2G	possibly damaging	Het
Itih1	A	G	14: 30,660,028 (GRCm39)	F231S	probably damaging	Het
Jrkl	A	T	9: 13,244,913 (GRCm39)	Y249*	probably null	Het
Kat6a	AGAGGAGGAGGAGGAGGAGGAGGAG	AGAGGAGGAGGAGGAGGAGGAG	8: 23,425,663 (GRCm39)		probably benign	Het
Katnal2	A	T	18: 77,098,637 (GRCm39)	S184R	probably benign	Het
Kcnh5	T	A	12: 74,945,230 (GRCm39)		probably null	Het
Kcnj11	G	T	7: 45,748,781 (GRCm39)	L181I	probably damaging	Het
Klhl2	T	C	8: 65,202,804 (GRCm39)	T465A	probably benign	Het
Krt90	T	A	15: 101,471,046 (GRCm39)	Y72F	probably benign	Het
Lig4	G	A	8: 10,022,766 (GRCm39)	T338I	probably benign	Het
Lrrc37	T	C	11: 103,511,285 (GRCm39)	T228A	unknown	Het
Magel2	T	C	7: 62,030,540 (GRCm39)	V1148A	unknown	Het
Mak	C	A	13: 41,186,020 (GRCm39)	E549D	probably benign	Het
Marf1	G	T	16: 13,950,293 (GRCm39)	S1001Y	probably damaging	Het
Mcoln1	G	A	8: 3,561,787 (GRCm39)	V446I	probably damaging	Het
Meig1	T	C	2: 3,410,290 (GRCm39)	N70S	probably benign	Het
Mfsd14a	G	A	3: 116,441,479 (GRCm39)	T108I	probably damaging	Het
Mocs1	G	A	17: 49,761,386 (GRCm39)	M493I	probably damaging	Het
Mrpl11	C	A	19: 5,012,497 (GRCm39)	A26E	probably damaging	Het
Myh6	A	T	14: 55,191,251 (GRCm39)	D863E	probably benign	Het
Myom2	T	A	8: 15,134,555 (GRCm39)	Y453N	probably damaging	Het
Nhlh1	A	G	1: 171,881,524 (GRCm39)	I114T	probably damaging	Het
Odr4	A	G	1: 150,258,086 (GRCm39)	V183A	possibly damaging	Het
Or12j4	A	C	7: 140,046,504 (GRCm39)	H130P	probably benign	Het
Or2y3	G	T	17: 38,393,071 (GRCm39)	P266Q	probably damaging	Het
Or4k5	A	T	14: 50,386,154 (GRCm39)	M59K	probably damaging	Het
Or5k17	G	T	16: 58,746,486 (GRCm39)	F149L	probably benign	Het
Or5p80	C	G	7: 108,229,984 (GRCm39)	P262A	probably damaging	Het
Pclo	T	C	5: 14,764,309 (GRCm39)	S976P	probably benign	Het
Pde3a	G	A	6: 141,429,640 (GRCm39)	E734K	possibly damaging	Het
Pdzd2	A	T	15: 12,375,879 (GRCm39)	S1419T	probably benign	Het
Pdzd8	T	A	19: 59,288,853 (GRCm39)	Y849F	probably damaging	Het
Phldb3	A	G	7: 24,312,070 (GRCm39)	E128G	probably damaging	Het
Polg	A	G	7: 79,111,468 (GRCm39)	I261T	possibly damaging	Het
Ppp1r35	T	C	5: 137,778,267 (GRCm39)	M254T	probably benign	Het
Ppp3ca	G	T	3: 136,596,211 (GRCm39)	R292M	possibly damaging	Het
Ptk7	T	A	17: 46,890,543 (GRCm39)	T430S	probably benign	Het
Ptrh1	T	A	2: 32,667,040 (GRCm39)	N144K	possibly damaging	Het
Rbfox1	A	G	16: 7,111,946 (GRCm39)	T211A	possibly damaging	Het
Rbpjl	A	G	2: 164,256,343 (GRCm39)	D443G	possibly damaging	Het
Rcc1	A	G	4: 132,065,360 (GRCm39)		probably null	Het
Rimbp2	G	T	5: 128,865,229 (GRCm39)	S706R	probably damaging	Het
Rsph10b	G	C	5: 143,898,074 (GRCm39)	E96D	probably benign	Het
Scn10a	A	T	9: 119,438,514 (GRCm39)	I1784K	probably benign	Het
Sfxn2	A	G	19: 46,579,985 (GRCm39)		probably null	Het
Slamf6	T	A	1: 171,765,575 (GRCm39)	L233Q	probably damaging	Het
Slc17a5	A	T	9: 78,484,455 (GRCm39)	Y102N	probably damaging	Het
Slc25a53	T	C	X: 135,884,216 (GRCm39)	T42A	probably damaging	Het
Slco1a8	T	C	6: 141,926,670 (GRCm39)	D552G	probably damaging	Het
Smg7	G	A	1: 152,716,064 (GRCm39)	T1057I	possibly damaging	Het
Speer2	T	A	16: 69,657,485 (GRCm39)	T53S	possibly damaging	Het
Srm	A	C	4: 148,676,948 (GRCm39)	I100L	probably benign	Het
Stoml3	A	C	3: 53,415,008 (GRCm39)	N267H	probably damaging	Het
Thsd7a	A	C	6: 12,379,632 (GRCm39)	C931G	probably damaging	Het
Tlr11	A	G	14: 50,598,139 (GRCm39)	I42V	probably benign	Het
Tmigd1	T	C	11: 76,800,999 (GRCm39)	V162A	probably benign	Het
Tmx3	A	G	18: 90,528,505 (GRCm39)		probably null	Het
Topors	T	A	4: 40,262,790 (GRCm39)	R165W	possibly damaging	Het
Ttc17	A	T	2: 94,196,987 (GRCm39)	S453R	possibly damaging	Het
Vmn1r49	G	T	6: 90,049,441 (GRCm39)	T187N	probably damaging	Het
Zbtb49	A	T	5: 38,371,464 (GRCm39)	V139E	possibly damaging	Het
Zfp11	T	C	5: 129,734,216 (GRCm39)	H415R	probably damaging	Het
Zfp677	A	T	17: 21,617,970 (GRCm39)	K342N	probably benign	Het
Zfp979	A	C	4: 147,697,915 (GRCm39)	C265G	possibly damaging	Het
Zfpl1	T	C	19: 6,134,459 (GRCm39)	R9G	probably damaging	Het
Zkscan8	A	T	13: 21,704,759 (GRCm39)	C321*	probably null	Het

Other mutations in Igsf10

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00773:Igsf10	APN	3	59,238,960 (GRCm39)	missense	probably benign	0.03
IGL00790:Igsf10	APN	3	59,226,938 (GRCm39)	missense	probably damaging	1.00
IGL00916:Igsf10	APN	3	59,238,548 (GRCm39)	missense	probably damaging	0.97
IGL00928:Igsf10	APN	3	59,238,018 (GRCm39)	missense	probably benign	0.00
IGL01066:Igsf10	APN	3	59,235,203 (GRCm39)	critical splice donor site	probably null
IGL01107:Igsf10	APN	3	59,238,945 (GRCm39)	missense	probably damaging	1.00
IGL01420:Igsf10	APN	3	59,227,071 (GRCm39)	missense	probably benign	0.02
IGL01533:Igsf10	APN	3	59,226,651 (GRCm39)	missense	probably damaging	0.98
IGL01537:Igsf10	APN	3	59,237,452 (GRCm39)	missense	probably benign	0.00
IGL01676:Igsf10	APN	3	59,236,756 (GRCm39)	missense	probably benign	0.17
IGL01676:Igsf10	APN	3	59,233,432 (GRCm39)	missense	probably benign	0.06
IGL01960:Igsf10	APN	3	59,226,158 (GRCm39)	missense	probably benign	0.00
IGL02123:Igsf10	APN	3	59,226,081 (GRCm39)	missense	probably damaging	0.97
IGL02198:Igsf10	APN	3	59,233,399 (GRCm39)	missense	possibly damaging	0.95
IGL02268:Igsf10	APN	3	59,238,573 (GRCm39)	nonsense	probably null
IGL02313:Igsf10	APN	3	59,238,111 (GRCm39)	missense	probably benign	0.01
IGL02368:Igsf10	APN	3	59,235,652 (GRCm39)	missense	probably benign
IGL02494:Igsf10	APN	3	59,235,427 (GRCm39)	missense	probably damaging	0.98
IGL02549:Igsf10	APN	3	59,236,662 (GRCm39)	missense	probably benign	0.03
IGL02616:Igsf10	APN	3	59,226,027 (GRCm39)	missense	probably benign	0.06
IGL02957:Igsf10	APN	3	59,238,285 (GRCm39)	missense	probably damaging	1.00
IGL03067:Igsf10	APN	3	59,226,339 (GRCm39)	missense	probably benign	0.25
IGL03104:Igsf10	APN	3	59,226,905 (GRCm39)	missense	probably damaging	1.00
IGL03124:Igsf10	APN	3	59,227,086 (GRCm39)	missense	probably benign	0.01
IGL03212:Igsf10	APN	3	59,235,586 (GRCm39)	missense	probably benign	0.09
IGL03347:Igsf10	APN	3	59,239,321 (GRCm39)	missense	possibly damaging	0.94
IGL03357:Igsf10	APN	3	59,243,632 (GRCm39)	missense	probably benign	0.35
F6893:Igsf10	UTSW	3	59,238,481 (GRCm39)	missense	probably damaging	1.00
FR4449:Igsf10	UTSW	3	59,226,531 (GRCm39)	missense	probably damaging	1.00
PIT1430001:Igsf10	UTSW	3	59,235,579 (GRCm39)	missense	probably benign	0.06
PIT4402001:Igsf10	UTSW	3	59,233,000 (GRCm39)	missense	probably benign	0.00
PIT4810001:Igsf10	UTSW	3	59,225,903 (GRCm39)	missense	probably damaging	1.00
R0068:Igsf10	UTSW	3	59,238,045 (GRCm39)	missense	probably damaging	0.98
R0095:Igsf10	UTSW	3	59,238,617 (GRCm39)	nonsense	probably null
R0095:Igsf10	UTSW	3	59,238,617 (GRCm39)	nonsense	probably null
R0112:Igsf10	UTSW	3	59,233,429 (GRCm39)	missense	probably benign	0.00
R0141:Igsf10	UTSW	3	59,238,253 (GRCm39)	missense	probably damaging	1.00
R0538:Igsf10	UTSW	3	59,227,527 (GRCm39)	missense	probably damaging	0.99
R0551:Igsf10	UTSW	3	59,236,089 (GRCm39)	missense	probably benign	0.01
R0556:Igsf10	UTSW	3	59,236,296 (GRCm39)	missense	probably benign	0.02
R0582:Igsf10	UTSW	3	59,227,188 (GRCm39)	missense	probably benign	0.00
R0630:Igsf10	UTSW	3	59,233,483 (GRCm39)	missense	probably damaging	1.00
R0675:Igsf10	UTSW	3	59,236,015 (GRCm39)	missense	probably benign	0.14
R0948:Igsf10	UTSW	3	59,238,525 (GRCm39)	missense	probably damaging	1.00
R1252:Igsf10	UTSW	3	59,239,269 (GRCm39)	missense	probably benign	0.03
R1412:Igsf10	UTSW	3	59,235,196 (GRCm39)	splice site	probably benign
R1473:Igsf10	UTSW	3	59,226,188 (GRCm39)	missense	probably damaging	1.00
R1585:Igsf10	UTSW	3	59,237,838 (GRCm39)	missense	probably damaging	1.00
R1650:Igsf10	UTSW	3	59,233,583 (GRCm39)	missense	probably damaging	1.00
R1660:Igsf10	UTSW	3	59,238,706 (GRCm39)	missense	probably damaging	1.00
R1671:Igsf10	UTSW	3	59,235,921 (GRCm39)	nonsense	probably null
R1748:Igsf10	UTSW	3	59,226,514 (GRCm39)	missense	probably damaging	1.00
R1758:Igsf10	UTSW	3	59,236,617 (GRCm39)	missense	probably benign	0.09
R1856:Igsf10	UTSW	3	59,238,693 (GRCm39)	missense	possibly damaging	0.63
R1912:Igsf10	UTSW	3	59,236,993 (GRCm39)	missense	probably benign	0.40
R2148:Igsf10	UTSW	3	59,243,998 (GRCm39)	missense	possibly damaging	0.77
R2509:Igsf10	UTSW	3	59,239,287 (GRCm39)	missense	probably damaging	1.00
R2511:Igsf10	UTSW	3	59,239,287 (GRCm39)	missense	probably damaging	1.00
R2680:Igsf10	UTSW	3	59,232,875 (GRCm39)	missense	probably benign	0.14
R2913:Igsf10	UTSW	3	59,239,157 (GRCm39)	missense	possibly damaging	0.70
R2927:Igsf10	UTSW	3	59,236,848 (GRCm39)	missense	probably benign
R3547:Igsf10	UTSW	3	59,243,935 (GRCm39)	missense	probably damaging	1.00
R3547:Igsf10	UTSW	3	59,237,962 (GRCm39)	missense	probably benign	0.02
R3548:Igsf10	UTSW	3	59,243,935 (GRCm39)	missense	probably damaging	1.00
R3620:Igsf10	UTSW	3	59,243,752 (GRCm39)	missense	probably damaging	1.00
R3732:Igsf10	UTSW	3	59,233,135 (GRCm39)	missense	probably benign	0.29
R3743:Igsf10	UTSW	3	59,233,546 (GRCm39)	missense	possibly damaging	0.69
R3973:Igsf10	UTSW	3	59,239,345 (GRCm39)	missense	probably damaging	1.00
R4005:Igsf10	UTSW	3	59,235,981 (GRCm39)	missense	probably benign	0.00
R4184:Igsf10	UTSW	3	59,227,152 (GRCm39)	missense	probably damaging	1.00
R4302:Igsf10	UTSW	3	59,226,171 (GRCm39)	missense	probably damaging	1.00
R4404:Igsf10	UTSW	3	59,236,972 (GRCm39)	missense	probably benign	0.04
R4575:Igsf10	UTSW	3	59,237,521 (GRCm39)	missense	probably benign
R4676:Igsf10	UTSW	3	59,233,370 (GRCm39)	missense	probably benign	0.23
R4700:Igsf10	UTSW	3	59,227,751 (GRCm39)	missense	probably damaging	0.99
R4765:Igsf10	UTSW	3	59,237,126 (GRCm39)	missense	probably benign	0.01
R4986:Igsf10	UTSW	3	59,236,027 (GRCm39)	missense	probably benign	0.24
R5012:Igsf10	UTSW	3	59,226,143 (GRCm39)	missense	probably damaging	1.00
R5070:Igsf10	UTSW	3	59,235,714 (GRCm39)	missense	probably benign	0.02
R5083:Igsf10	UTSW	3	59,233,694 (GRCm39)	missense	probably damaging	1.00
R5336:Igsf10	UTSW	3	59,227,553 (GRCm39)	missense	probably damaging	1.00
R5462:Igsf10	UTSW	3	59,233,175 (GRCm39)	missense	probably damaging	1.00
R5648:Igsf10	UTSW	3	59,235,574 (GRCm39)	missense	probably benign	0.01
R5810:Igsf10	UTSW	3	59,226,492 (GRCm39)	missense	probably damaging	1.00
R5871:Igsf10	UTSW	3	59,237,832 (GRCm39)	missense	possibly damaging	0.83
R5880:Igsf10	UTSW	3	59,238,252 (GRCm39)	missense	probably damaging	1.00
R5935:Igsf10	UTSW	3	59,235,578 (GRCm39)	missense	probably benign	0.12
R5979:Igsf10	UTSW	3	59,243,894 (GRCm39)	missense	probably damaging	1.00
R6145:Igsf10	UTSW	3	59,239,077 (GRCm39)	missense	possibly damaging	0.83
R6222:Igsf10	UTSW	3	59,226,336 (GRCm39)	missense	possibly damaging	0.90
R6224:Igsf10	UTSW	3	59,232,931 (GRCm39)	missense	probably damaging	1.00
R6264:Igsf10	UTSW	3	59,235,928 (GRCm39)	missense	possibly damaging	0.88
R6283:Igsf10	UTSW	3	59,226,870 (GRCm39)	missense	probably damaging	1.00
R6336:Igsf10	UTSW	3	59,237,760 (GRCm39)	missense	probably benign	0.00
R6490:Igsf10	UTSW	3	59,236,992 (GRCm39)	missense	probably benign	0.06
R6785:Igsf10	UTSW	3	59,226,665 (GRCm39)	missense	probably damaging	1.00
R6873:Igsf10	UTSW	3	59,235,865 (GRCm39)	missense	probably benign
R6889:Igsf10	UTSW	3	59,239,354 (GRCm39)	missense	probably benign
R7024:Igsf10	UTSW	3	59,239,122 (GRCm39)	missense	probably benign	0.00
R7056:Igsf10	UTSW	3	59,238,501 (GRCm39)	missense	probably damaging	1.00
R7128:Igsf10	UTSW	3	59,236,326 (GRCm39)	missense	probably benign
R7251:Igsf10	UTSW	3	59,226,875 (GRCm39)	missense	probably damaging	1.00
R7313:Igsf10	UTSW	3	59,236,837 (GRCm39)	missense	probably benign	0.05
R7340:Igsf10	UTSW	3	59,233,189 (GRCm39)	missense	probably damaging	1.00
R7447:Igsf10	UTSW	3	59,239,222 (GRCm39)	missense	probably benign	0.39
R7506:Igsf10	UTSW	3	59,226,775 (GRCm39)	missense	probably damaging	1.00
R7678:Igsf10	UTSW	3	59,226,761 (GRCm39)	missense	possibly damaging	0.81
R7695:Igsf10	UTSW	3	59,233,612 (GRCm39)	missense	probably damaging	1.00
R7709:Igsf10	UTSW	3	59,238,964 (GRCm39)	missense	probably damaging	0.96
R7749:Igsf10	UTSW	3	59,236,549 (GRCm39)	missense	possibly damaging	0.88
R7808:Igsf10	UTSW	3	59,235,489 (GRCm39)	missense	probably benign	0.00
R7850:Igsf10	UTSW	3	59,227,053 (GRCm39)	missense	probably benign	0.33
R7879:Igsf10	UTSW	3	59,238,145 (GRCm39)	missense	probably damaging	1.00
R7886:Igsf10	UTSW	3	59,235,748 (GRCm39)	missense	probably benign	0.01
R7891:Igsf10	UTSW	3	59,235,832 (GRCm39)	nonsense	probably null
R7946:Igsf10	UTSW	3	59,227,125 (GRCm39)	missense	possibly damaging	0.69
R7948:Igsf10	UTSW	3	59,239,279 (GRCm39)	missense	probably benign	0.02
R8004:Igsf10	UTSW	3	59,237,130 (GRCm39)	missense	probably benign	0.01
R8096:Igsf10	UTSW	3	59,236,380 (GRCm39)	missense	probably damaging	0.98
R8141:Igsf10	UTSW	3	59,237,949 (GRCm39)	missense	probably damaging	0.96
R8183:Igsf10	UTSW	3	59,238,036 (GRCm39)	missense	probably benign	0.04
R8203:Igsf10	UTSW	3	59,236,254 (GRCm39)	missense	probably benign	0.11
R8325:Igsf10	UTSW	3	59,225,954 (GRCm39)	missense	probably damaging	0.96
R8350:Igsf10	UTSW	3	59,238,949 (GRCm39)	missense	probably damaging	1.00
R8387:Igsf10	UTSW	3	59,236,564 (GRCm39)	missense	probably damaging	1.00
R8488:Igsf10	UTSW	3	59,227,431 (GRCm39)	missense	probably damaging	1.00
R8697:Igsf10	UTSW	3	59,226,308 (GRCm39)	missense	probably benign	0.02
R8786:Igsf10	UTSW	3	59,238,063 (GRCm39)	missense	probably benign	0.25
R8804:Igsf10	UTSW	3	59,243,876 (GRCm39)	missense	probably damaging	1.00
R8886:Igsf10	UTSW	3	59,237,410 (GRCm39)	missense	probably benign	0.00
R8902:Igsf10	UTSW	3	59,243,633 (GRCm39)	missense	probably benign	0.00
R8906:Igsf10	UTSW	3	59,233,739 (GRCm39)	missense	probably benign	0.01
R8917:Igsf10	UTSW	3	59,226,888 (GRCm39)	missense	possibly damaging	0.69
R9051:Igsf10	UTSW	3	59,236,668 (GRCm39)	missense	probably benign	0.00
R9178:Igsf10	UTSW	3	59,233,480 (GRCm39)	missense	possibly damaging	0.69
R9228:Igsf10	UTSW	3	59,243,843 (GRCm39)	missense	probably damaging	1.00
R9230:Igsf10	UTSW	3	59,243,843 (GRCm39)	missense	probably damaging	1.00
R9231:Igsf10	UTSW	3	59,243,843 (GRCm39)	missense	probably damaging	1.00
R9232:Igsf10	UTSW	3	59,243,843 (GRCm39)	missense	probably damaging	1.00
R9417:Igsf10	UTSW	3	59,236,526 (GRCm39)	missense	possibly damaging	0.94
R9609:Igsf10	UTSW	3	59,226,869 (GRCm39)	missense	probably damaging	1.00
R9631:Igsf10	UTSW	3	59,237,904 (GRCm39)	missense	probably damaging	1.00
R9689:Igsf10	UTSW	3	59,233,624 (GRCm39)	missense	probably damaging	1.00
R9762:Igsf10	UTSW	3	59,237,106 (GRCm39)	missense	probably damaging	1.00
R9770:Igsf10	UTSW	3	59,227,199 (GRCm39)	missense	probably benign	0.07
R9798:Igsf10	UTSW	3	59,239,126 (GRCm39)	missense	probably damaging	1.00
Z1088:Igsf10	UTSW	3	59,237,359 (GRCm39)	missense	possibly damaging	0.59
Z1177:Igsf10	UTSW	3	59,237,026 (GRCm39)	nonsense	probably null

Predicted Primers

PCR Primer
(F):5'- CAGTTCTGTTGAGCTGCAGG -3'
(R):5'- CCGTCTCACCTCAAGATTTCATAG -3'

Sequencing Primer
(F):5'- GGATCTGCTTTGAAATCAGCC -3'
(R):5'- AGATTTCATAGAACCTTTTGGCTCC -3'

Posted On

2014-10-01