Mutagenetix > Incidental Mutation

Incidental Mutation 'R2155:Pdzd2'

234748

Institutional Source

Beutler Lab

Gene Symbol

Pdzd2

Ensembl Gene

ENSMUSG00000022197

Gene Name

PDZ domain containing 2

Synonyms

Gm21706, A930022H17Rik, Pdzk3, 4930537L06Rik, LOC223364

MMRRC Submission

040158-MU

Accession Numbers

Essential gene?

Probably non essential (E-score: 0.117) question?

Stock #

R2155 (G1)

Quality Score

225

Status

Not validated

Chromosome

Chromosomal Location

12359797-12740010 bp(-) (GRCm39)

Type of Mutation

missense

DNA Base Change (assembly)

A to T at 12375879 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Serine to Threonine at position 1419 (S1419T)

Ref Sequence

ENSEMBL: ENSMUSP00000074788 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000075317]

AlphaFold

no structure available at present

Predicted Effect

probably benign
Transcript: ENSMUST00000075317
AA Change: S1419T

PolyPhen 2 Score 0.428 (Sensitivity: 0.89; Specificity: 0.90)

SMART Domains

Protein: ENSMUSP00000074788
Gene: ENSMUSG00000022197
AA Change: S1419T

Domain	Start	End	E-Value	Type
PDZ	81	179	1.27e-2	SMART
PDZ	342	419	1.51e-18	SMART
PDZ	597	675	5.25e-18	SMART
low complexity region	690	718	N/A	INTRINSIC
PDZ	738	817	1.64e-10	SMART
low complexity region	861	869	N/A	INTRINSIC
low complexity region	969	984	N/A	INTRINSIC
low complexity region	986	1000	N/A	INTRINSIC
low complexity region	1436	1459	N/A	INTRINSIC
low complexity region	1525	1537	N/A	INTRINSIC
low complexity region	1538	1553	N/A	INTRINSIC
low complexity region	1567	1586	N/A	INTRINSIC
low complexity region	2111	2129	N/A	INTRINSIC
low complexity region	2190	2198	N/A	INTRINSIC
low complexity region	2335	2354	N/A	INTRINSIC
low complexity region	2469	2479	N/A	INTRINSIC
PDZ	2589	2666	1.3e-13	SMART
PDZ	2716	2794	9.42e-20	SMART

Coding Region Coverage

1x: 99.2%
3x: 98.6%
10x: 97.4%
20x: 95.4%

Validation Efficiency

MGI Phenotype

FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] The protein encoded by this gene contains six PDZ domains and shares sequence similarity with pro-interleukin-16 (pro-IL-16). Like pro-IL-16, the encoded protein localizes to the endoplasmic reticulum and is thought to be cleaved by a caspase to produce a secreted peptide containing two PDZ domains. In addition, this gene is upregulated in primary prostate tumors and may be involved in the early stages of prostate tumorigenesis. [provided by RefSeq, Dec 2015]
PHENOTYPE: Mice homozygous for a gene trapped allele exhibit normal response to acute and chronic pain. [provided by MGI curators]

Allele List at MGI

Other mutations in this stock

Total: 89 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
2610318N02Rik	A	G	16: 16,939,260 (GRCm39)	L41P	probably damaging	Het
Aff4	C	T	11: 53,290,446 (GRCm39)	L469F	probably damaging	Het
AI182371	G	A	2: 34,975,366 (GRCm39)	H288Y	probably benign	Het
AK157302	A	T	13: 21,679,827 (GRCm39)	K118*	probably null	Het
Arhgef2	G	A	3: 88,543,351 (GRCm39)	R454Q	probably damaging	Het
Asb17	C	T	3: 153,550,322 (GRCm39)	T118M	probably damaging	Het
Atp7b	A	G	8: 22,503,600 (GRCm39)	V718A	possibly damaging	Het
Cdca2	A	G	14: 67,952,287 (GRCm39)	L28S	probably damaging	Het
Cdh20	G	T	1: 109,976,594 (GRCm39)	L86F	probably damaging	Het
Cela2a	A	T	4: 141,545,350 (GRCm39)		probably null	Het
Cers3	T	A	7: 66,433,162 (GRCm39)	Y160N	probably damaging	Het
Chmp2b	A	G	16: 65,343,877 (GRCm39)	V56A	probably benign	Het
Cryl1	A	G	14: 57,635,880 (GRCm39)	V9A	unknown	Het
Dmbt1	A	T	7: 130,699,305 (GRCm39)	H978L	possibly damaging	Het
Dnm1	C	T	2: 32,204,949 (GRCm39)	V673M	probably damaging	Het
Dtx4	T	A	19: 12,462,646 (GRCm39)	K378*	probably null	Het
Extl1	A	T	4: 134,090,491 (GRCm39)	M328K	possibly damaging	Het
Fcgbp	T	C	7: 27,806,628 (GRCm39)	S2199P	probably benign	Het
Glis3	G	T	19: 28,508,702 (GRCm39)	N427K	probably benign	Het
Hdac7	T	C	15: 97,691,944 (GRCm39)	K810E	probably benign	Het
Hesx1	A	G	14: 26,723,434 (GRCm39)	E88G	probably benign	Het
Hmcn2	A	T	2: 31,350,361 (GRCm39)	Q5086L	possibly damaging	Het
Ier3	A	G	17: 36,133,101 (GRCm39)	T128A	probably benign	Het
Igsf10	G	T	3: 59,239,101 (GRCm39)	T360K	probably damaging	Het
Ilkap	A	C	1: 91,312,345 (GRCm39)	C2G	possibly damaging	Het
Itih1	A	G	14: 30,660,028 (GRCm39)	F231S	probably damaging	Het
Jrkl	A	T	9: 13,244,913 (GRCm39)	Y249*	probably null	Het
Kat6a	AGAGGAGGAGGAGGAGGAGGAGGAG	AGAGGAGGAGGAGGAGGAGGAG	8: 23,425,663 (GRCm39)		probably benign	Het
Katnal2	A	T	18: 77,098,637 (GRCm39)	S184R	probably benign	Het
Kcnh5	T	A	12: 74,945,230 (GRCm39)		probably null	Het
Kcnj11	G	T	7: 45,748,781 (GRCm39)	L181I	probably damaging	Het
Klhl2	T	C	8: 65,202,804 (GRCm39)	T465A	probably benign	Het
Krt90	T	A	15: 101,471,046 (GRCm39)	Y72F	probably benign	Het
Lig4	G	A	8: 10,022,766 (GRCm39)	T338I	probably benign	Het
Lrrc37	T	C	11: 103,511,285 (GRCm39)	T228A	unknown	Het
Magel2	T	C	7: 62,030,540 (GRCm39)	V1148A	unknown	Het
Mak	C	A	13: 41,186,020 (GRCm39)	E549D	probably benign	Het
Marf1	G	T	16: 13,950,293 (GRCm39)	S1001Y	probably damaging	Het
Mcoln1	G	A	8: 3,561,787 (GRCm39)	V446I	probably damaging	Het
Meig1	T	C	2: 3,410,290 (GRCm39)	N70S	probably benign	Het
Mfsd14a	G	A	3: 116,441,479 (GRCm39)	T108I	probably damaging	Het
Mocs1	G	A	17: 49,761,386 (GRCm39)	M493I	probably damaging	Het
Mrpl11	C	A	19: 5,012,497 (GRCm39)	A26E	probably damaging	Het
Myh6	A	T	14: 55,191,251 (GRCm39)	D863E	probably benign	Het
Myom2	T	A	8: 15,134,555 (GRCm39)	Y453N	probably damaging	Het
Nhlh1	A	G	1: 171,881,524 (GRCm39)	I114T	probably damaging	Het
Odr4	A	G	1: 150,258,086 (GRCm39)	V183A	possibly damaging	Het
Or12j4	A	C	7: 140,046,504 (GRCm39)	H130P	probably benign	Het
Or2y3	G	T	17: 38,393,071 (GRCm39)	P266Q	probably damaging	Het
Or4k5	A	T	14: 50,386,154 (GRCm39)	M59K	probably damaging	Het
Or5k17	G	T	16: 58,746,486 (GRCm39)	F149L	probably benign	Het
Or5p80	C	G	7: 108,229,984 (GRCm39)	P262A	probably damaging	Het
Pclo	T	C	5: 14,764,309 (GRCm39)	S976P	probably benign	Het
Pde3a	G	A	6: 141,429,640 (GRCm39)	E734K	possibly damaging	Het
Pdzd8	T	A	19: 59,288,853 (GRCm39)	Y849F	probably damaging	Het
Phldb3	A	G	7: 24,312,070 (GRCm39)	E128G	probably damaging	Het
Polg	A	G	7: 79,111,468 (GRCm39)	I261T	possibly damaging	Het
Ppp1r35	T	C	5: 137,778,267 (GRCm39)	M254T	probably benign	Het
Ppp3ca	G	T	3: 136,596,211 (GRCm39)	R292M	possibly damaging	Het
Ptk7	T	A	17: 46,890,543 (GRCm39)	T430S	probably benign	Het
Ptrh1	T	A	2: 32,667,040 (GRCm39)	N144K	possibly damaging	Het
Rbfox1	A	G	16: 7,111,946 (GRCm39)	T211A	possibly damaging	Het
Rbpjl	A	G	2: 164,256,343 (GRCm39)	D443G	possibly damaging	Het
Rcc1	A	G	4: 132,065,360 (GRCm39)		probably null	Het
Rimbp2	G	T	5: 128,865,229 (GRCm39)	S706R	probably damaging	Het
Rsph10b	G	C	5: 143,898,074 (GRCm39)	E96D	probably benign	Het
Scn10a	A	T	9: 119,438,514 (GRCm39)	I1784K	probably benign	Het
Sfxn2	A	G	19: 46,579,985 (GRCm39)		probably null	Het
Slamf6	T	A	1: 171,765,575 (GRCm39)	L233Q	probably damaging	Het
Slc17a5	A	T	9: 78,484,455 (GRCm39)	Y102N	probably damaging	Het
Slc25a53	T	C	X: 135,884,216 (GRCm39)	T42A	probably damaging	Het
Slco1a8	T	C	6: 141,926,670 (GRCm39)	D552G	probably damaging	Het
Smg7	G	A	1: 152,716,064 (GRCm39)	T1057I	possibly damaging	Het
Speer2	T	A	16: 69,657,485 (GRCm39)	T53S	possibly damaging	Het
Srm	A	C	4: 148,676,948 (GRCm39)	I100L	probably benign	Het
Stoml3	A	C	3: 53,415,008 (GRCm39)	N267H	probably damaging	Het
Thsd7a	A	C	6: 12,379,632 (GRCm39)	C931G	probably damaging	Het
Tlr11	A	G	14: 50,598,139 (GRCm39)	I42V	probably benign	Het
Tmigd1	T	C	11: 76,800,999 (GRCm39)	V162A	probably benign	Het
Tmx3	A	G	18: 90,528,505 (GRCm39)		probably null	Het
Topors	T	A	4: 40,262,790 (GRCm39)	R165W	possibly damaging	Het
Ttc17	A	T	2: 94,196,987 (GRCm39)	S453R	possibly damaging	Het
Vmn1r49	G	T	6: 90,049,441 (GRCm39)	T187N	probably damaging	Het
Zbtb49	A	T	5: 38,371,464 (GRCm39)	V139E	possibly damaging	Het
Zfp11	T	C	5: 129,734,216 (GRCm39)	H415R	probably damaging	Het
Zfp677	A	T	17: 21,617,970 (GRCm39)	K342N	probably benign	Het
Zfp979	A	C	4: 147,697,915 (GRCm39)	C265G	possibly damaging	Het
Zfpl1	T	C	19: 6,134,459 (GRCm39)	R9G	probably damaging	Het
Zkscan8	A	T	13: 21,704,759 (GRCm39)	C321*	probably null	Het

Other mutations in Pdzd2

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00159:Pdzd2	APN	15	12,458,069 (GRCm39)	missense	possibly damaging	0.93
IGL00586:Pdzd2	APN	15	12,365,853 (GRCm39)	splice site	probably null
IGL00697:Pdzd2	APN	15	12,373,733 (GRCm39)	missense	possibly damaging	0.81
IGL00721:Pdzd2	APN	15	12,374,498 (GRCm39)	missense	probably benign	0.00
IGL00971:Pdzd2	APN	15	12,374,804 (GRCm39)	missense	probably benign	0.00
IGL01066:Pdzd2	APN	15	12,402,718 (GRCm39)	unclassified	probably benign
IGL01389:Pdzd2	APN	15	12,374,712 (GRCm39)	missense	possibly damaging	0.56
IGL01505:Pdzd2	APN	15	12,458,293 (GRCm39)	missense	probably damaging	1.00
IGL01527:Pdzd2	APN	15	12,445,750 (GRCm39)	missense	probably damaging	1.00
IGL01584:Pdzd2	APN	15	12,592,569 (GRCm39)	missense	probably damaging	1.00
IGL01763:Pdzd2	APN	15	12,372,632 (GRCm39)	missense	probably benign
IGL01915:Pdzd2	APN	15	12,371,725 (GRCm39)	missense	probably damaging	1.00
IGL01947:Pdzd2	APN	15	12,592,440 (GRCm39)	missense	probably damaging	1.00
IGL02058:Pdzd2	APN	15	12,376,382 (GRCm39)	missense	possibly damaging	0.87
IGL02274:Pdzd2	APN	15	12,445,735 (GRCm39)	missense	probably damaging	1.00
IGL02408:Pdzd2	APN	15	12,375,851 (GRCm39)	missense	probably benign	0.00
IGL02600:Pdzd2	APN	15	12,411,105 (GRCm39)	missense	probably damaging	1.00
IGL02637:Pdzd2	APN	15	12,385,720 (GRCm39)	missense	probably benign	0.13
IGL02639:Pdzd2	APN	15	12,592,329 (GRCm39)	missense	probably damaging	1.00
IGL02712:Pdzd2	APN	15	12,376,113 (GRCm39)	missense	probably benign	0.00
IGL02967:Pdzd2	APN	15	12,374,427 (GRCm39)	missense	probably benign	0.04
IGL02992:Pdzd2	APN	15	12,382,708 (GRCm39)	missense	possibly damaging	0.77
IGL03005:Pdzd2	APN	15	12,385,351 (GRCm39)	missense	probably damaging	1.00
IGL03067:Pdzd2	APN	15	12,388,628 (GRCm39)	critical splice donor site	probably null
IGL03335:Pdzd2	APN	15	12,373,850 (GRCm39)	missense	probably benign	0.00
PIT4280001:Pdzd2	UTSW	15	12,399,374 (GRCm39)	missense	probably damaging	1.00
R0022:Pdzd2	UTSW	15	12,371,691 (GRCm39)	missense	possibly damaging	0.94
R0241:Pdzd2	UTSW	15	12,368,027 (GRCm39)	missense	probably damaging	1.00
R0241:Pdzd2	UTSW	15	12,368,027 (GRCm39)	missense	probably damaging	1.00
R0446:Pdzd2	UTSW	15	12,375,110 (GRCm39)	missense	probably benign	0.43
R0462:Pdzd2	UTSW	15	12,592,246 (GRCm39)	missense	probably damaging	1.00
R0562:Pdzd2	UTSW	15	12,592,364 (GRCm39)	missense	probably damaging	1.00
R0589:Pdzd2	UTSW	15	12,376,385 (GRCm39)	missense	probably benign	0.03
R0639:Pdzd2	UTSW	15	12,458,144 (GRCm39)	missense	possibly damaging	0.77
R0925:Pdzd2	UTSW	15	12,399,356 (GRCm39)	missense	probably damaging	1.00
R1015:Pdzd2	UTSW	15	12,374,594 (GRCm39)	missense	probably damaging	1.00
R1054:Pdzd2	UTSW	15	12,371,725 (GRCm39)	missense	probably damaging	1.00
R1070:Pdzd2	UTSW	15	12,390,052 (GRCm39)	critical splice donor site	probably null
R1099:Pdzd2	UTSW	15	12,373,173 (GRCm39)	missense	probably damaging	1.00
R1122:Pdzd2	UTSW	15	12,457,981 (GRCm39)	missense	probably benign	0.25
R1126:Pdzd2	UTSW	15	12,458,306 (GRCm39)	missense	possibly damaging	0.94
R1381:Pdzd2	UTSW	15	12,385,525 (GRCm39)	missense	probably benign	0.02
R1385:Pdzd2	UTSW	15	12,411,108 (GRCm39)	missense	probably benign	0.38
R1513:Pdzd2	UTSW	15	12,373,915 (GRCm39)	missense	possibly damaging	0.88
R1538:Pdzd2	UTSW	15	12,373,047 (GRCm39)	missense	probably damaging	1.00
R1750:Pdzd2	UTSW	15	12,385,950 (GRCm39)	missense	probably damaging	1.00
R1775:Pdzd2	UTSW	15	12,592,546 (GRCm39)	missense	probably damaging	1.00
R1801:Pdzd2	UTSW	15	12,387,740 (GRCm39)	missense	possibly damaging	0.56
R1832:Pdzd2	UTSW	15	12,390,134 (GRCm39)	missense	probably damaging	1.00
R1856:Pdzd2	UTSW	15	12,373,941 (GRCm39)	missense	possibly damaging	0.87
R1870:Pdzd2	UTSW	15	12,457,972 (GRCm39)	missense	probably damaging	1.00
R1879:Pdzd2	UTSW	15	12,373,986 (GRCm39)	missense	possibly damaging	0.61
R2072:Pdzd2	UTSW	15	12,385,905 (GRCm39)	missense	probably damaging	1.00
R2073:Pdzd2	UTSW	15	12,385,905 (GRCm39)	missense	probably damaging	1.00
R2075:Pdzd2	UTSW	15	12,385,905 (GRCm39)	missense	probably damaging	1.00
R2125:Pdzd2	UTSW	15	12,373,676 (GRCm39)	missense	probably benign	0.37
R2142:Pdzd2	UTSW	15	12,406,645 (GRCm39)	missense	probably damaging	1.00
R2282:Pdzd2	UTSW	15	12,373,934 (GRCm39)	missense	possibly damaging	0.95
R2407:Pdzd2	UTSW	15	12,373,247 (GRCm39)	missense	probably damaging	1.00
R3545:Pdzd2	UTSW	15	12,375,557 (GRCm39)	missense	probably benign	0.00
R3878:Pdzd2	UTSW	15	12,376,262 (GRCm39)	missense	probably benign	0.00
R3879:Pdzd2	UTSW	15	12,375,594 (GRCm39)	missense	probably damaging	1.00
R4396:Pdzd2	UTSW	15	12,387,732 (GRCm39)	missense	probably benign	0.36
R4398:Pdzd2	UTSW	15	12,376,061 (GRCm39)	missense	probably benign	0.30
R4491:Pdzd2	UTSW	15	12,385,723 (GRCm39)	missense	possibly damaging	0.75
R4492:Pdzd2	UTSW	15	12,385,723 (GRCm39)	missense	possibly damaging	0.75
R4492:Pdzd2	UTSW	15	12,419,567 (GRCm39)	missense	possibly damaging	0.48
R4656:Pdzd2	UTSW	15	12,385,797 (GRCm39)	missense	probably benign	0.00
R4715:Pdzd2	UTSW	15	12,419,602 (GRCm39)	missense	possibly damaging	0.72
R4803:Pdzd2	UTSW	15	12,374,681 (GRCm39)	missense	probably benign	0.04
R4893:Pdzd2	UTSW	15	12,385,429 (GRCm39)	missense	probably benign	0.00
R4959:Pdzd2	UTSW	15	12,375,734 (GRCm39)	missense	probably damaging	1.00
R4973:Pdzd2	UTSW	15	12,375,734 (GRCm39)	missense	probably damaging	1.00
R5030:Pdzd2	UTSW	15	12,592,494 (GRCm39)	nonsense	probably null
R5174:Pdzd2	UTSW	15	12,372,600 (GRCm39)	missense	probably benign	0.01
R5230:Pdzd2	UTSW	15	12,390,119 (GRCm39)	missense	probably damaging	1.00
R5256:Pdzd2	UTSW	15	12,373,028 (GRCm39)	missense	possibly damaging	0.87
R5268:Pdzd2	UTSW	15	12,592,263 (GRCm39)	missense	probably damaging	1.00
R5488:Pdzd2	UTSW	15	12,382,762 (GRCm39)	missense	probably benign	0.00
R5489:Pdzd2	UTSW	15	12,382,762 (GRCm39)	missense	probably benign	0.00
R5588:Pdzd2	UTSW	15	12,374,367 (GRCm39)	missense	possibly damaging	0.48
R5605:Pdzd2	UTSW	15	12,592,436 (GRCm39)	nonsense	probably null
R5704:Pdzd2	UTSW	15	12,385,761 (GRCm39)	missense	probably benign	0.02
R5858:Pdzd2	UTSW	15	12,442,675 (GRCm39)	missense	probably damaging	0.97
R6048:Pdzd2	UTSW	15	12,592,656 (GRCm39)	splice site	probably null
R6222:Pdzd2	UTSW	15	12,374,652 (GRCm39)	missense	probably damaging	1.00
R6311:Pdzd2	UTSW	15	12,458,274 (GRCm39)	missense	probably damaging	1.00
R6734:Pdzd2	UTSW	15	12,592,551 (GRCm39)	missense	probably damaging	1.00
R6897:Pdzd2	UTSW	15	12,385,951 (GRCm39)	missense	probably damaging	1.00
R6900:Pdzd2	UTSW	15	12,374,123 (GRCm39)	missense	probably benign
R6955:Pdzd2	UTSW	15	12,401,550 (GRCm39)	missense	probably damaging	1.00
R6959:Pdzd2	UTSW	15	12,375,993 (GRCm39)	missense	probably benign	0.17
R6992:Pdzd2	UTSW	15	12,457,945 (GRCm39)	missense	probably damaging	1.00
R7014:Pdzd2	UTSW	15	12,373,061 (GRCm39)	missense	probably benign	0.14
R7014:Pdzd2	UTSW	15	12,372,647 (GRCm39)	missense	probably benign	0.13
R7110:Pdzd2	UTSW	15	12,368,099 (GRCm39)	missense	probably damaging	1.00
R7180:Pdzd2	UTSW	15	12,376,209 (GRCm39)	missense	probably damaging	0.99
R7228:Pdzd2	UTSW	15	12,458,231 (GRCm39)	nonsense	probably null
R7228:Pdzd2	UTSW	15	12,373,059 (GRCm39)	missense	probably benign	0.01
R7317:Pdzd2	UTSW	15	12,592,329 (GRCm39)	missense	probably damaging	1.00
R7322:Pdzd2	UTSW	15	12,437,248 (GRCm39)	missense	probably damaging	1.00
R7349:Pdzd2	UTSW	15	12,399,291 (GRCm39)	missense	probably damaging	1.00
R7600:Pdzd2	UTSW	15	12,372,820 (GRCm39)	missense	probably damaging	1.00
R7663:Pdzd2	UTSW	15	12,373,289 (GRCm39)	missense	probably damaging	1.00
R7712:Pdzd2	UTSW	15	12,407,422 (GRCm39)	missense	probably damaging	1.00
R7716:Pdzd2	UTSW	15	12,373,460 (GRCm39)	missense	possibly damaging	0.63
R7740:Pdzd2	UTSW	15	12,374,102 (GRCm39)	missense	probably benign	0.00
R7748:Pdzd2	UTSW	15	12,385,872 (GRCm39)	missense	possibly damaging	0.60
R8017:Pdzd2	UTSW	15	12,373,122 (GRCm39)	missense	probably damaging	1.00
R8019:Pdzd2	UTSW	15	12,373,122 (GRCm39)	missense	probably damaging	1.00
R8108:Pdzd2	UTSW	15	12,373,592 (GRCm39)	missense	probably benign	0.01
R8109:Pdzd2	UTSW	15	12,373,592 (GRCm39)	missense	probably benign	0.01
R8110:Pdzd2	UTSW	15	12,373,592 (GRCm39)	missense	probably benign	0.01
R8111:Pdzd2	UTSW	15	12,373,592 (GRCm39)	missense	probably benign	0.01
R8145:Pdzd2	UTSW	15	12,407,458 (GRCm39)	missense	probably benign	0.37
R8220:Pdzd2	UTSW	15	12,592,249 (GRCm39)	missense	probably damaging	0.99
R8278:Pdzd2	UTSW	15	12,375,995 (GRCm39)	missense	probably benign
R8768:Pdzd2	UTSW	15	12,437,252 (GRCm39)	missense	probably damaging	1.00
R8879:Pdzd2	UTSW	15	12,402,405 (GRCm39)	missense	probably damaging	1.00
R9019:Pdzd2	UTSW	15	12,375,612 (GRCm39)	missense	probably damaging	1.00
R9030:Pdzd2	UTSW	15	12,374,385 (GRCm39)	missense	probably benign	0.02
R9061:Pdzd2	UTSW	15	12,374,753 (GRCm39)	missense	possibly damaging	0.94
R9302:Pdzd2	UTSW	15	12,374,342 (GRCm39)	missense	possibly damaging	0.61
R9321:Pdzd2	UTSW	15	12,386,023 (GRCm39)	missense	probably benign	0.00
R9421:Pdzd2	UTSW	15	12,375,114 (GRCm39)	missense
R9515:Pdzd2	UTSW	15	12,374,621 (GRCm39)	missense	probably damaging	1.00
R9592:Pdzd2	UTSW	15	12,458,106 (GRCm39)	missense	probably damaging	1.00
R9614:Pdzd2	UTSW	15	12,375,486 (GRCm39)	missense	probably damaging	1.00
R9630:Pdzd2	UTSW	15	12,374,443 (GRCm39)	missense	probably benign	0.37
R9776:Pdzd2	UTSW	15	12,457,909 (GRCm39)	missense	probably benign	0.03
X0057:Pdzd2	UTSW	15	12,411,113 (GRCm39)	missense	probably damaging	1.00
X0063:Pdzd2	UTSW	15	12,368,805 (GRCm39)	missense	possibly damaging	0.77
X0066:Pdzd2	UTSW	15	12,372,942 (GRCm39)	missense	probably benign	0.00

Predicted Primers

PCR Primer
(F):5'- CGTGGAAACTGCTAAAATTTCTGG -3'
(R):5'- AGCTTGAAAGATAGGGCTCTGC -3'

Sequencing Primer
(F):5'- GAAAGTTTTTGTTCCCAGCCAACTG -3'
(R):5'- GCTCTGCTTGAAGAAACAGCGTC -3'

Posted On

2014-10-01