Mutagenetix > Incidental Mutation

Incidental Mutation 'R2188:Dnah1'

237943

Institutional Source

Beutler Lab

Gene Symbol

Dnah1

Ensembl Gene

ENSMUSG00000019027

Gene Name

dynein, axonemal, heavy chain 1

Synonyms

MDHC7, B230373P09Rik, ferf1, G1-415-19, E030034C22Rik, Dnahc1

MMRRC Submission

040190-MU

Accession Numbers

Essential gene?

Non essential (E-score: 0.000) question?

Stock #

R2188 (G1)

Quality Score

225

Status

Not validated

Chromosome

Chromosomal Location

30982332-31045853 bp(-) (GRCm39)

Type of Mutation

missense

DNA Base Change (assembly)

A to G at 31001121 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Isoleucine to Threonine at position 2408 (I2408T)

Ref Sequence

ENSEMBL: ENSMUSP00000043281 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000048603]

AlphaFold

no structure available at present

Predicted Effect

probably damaging
Transcript: ENSMUST00000048603
AA Change: I2408T

PolyPhen 2 Score 0.983 (Sensitivity: 0.75; Specificity: 0.96)

SMART Domains

Protein: ENSMUSP00000043281
Gene: ENSMUSG00000019027
AA Change: I2408T

Domain	Start	End	E-Value	Type
low complexity region	43	59	N/A	INTRINSIC
Pfam:DHC_N2	998	1404	6.3e-146	PFAM
AAA	1558	1697	6.02e-1	SMART
AAA	1839	2077	4.66e0	SMART
low complexity region	2149	2157	N/A	INTRINSIC
AAA	2204	2353	2.35e-1	SMART
Pfam:AAA_8	2533	2803	7.7e-84	PFAM
Pfam:MT	2815	3165	9.9e-57	PFAM
Pfam:AAA_9	3185	3410	1.1e-93	PFAM
Pfam:Dynein_heavy	3545	4246	2.7e-275	PFAM

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000228755

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000228927

Coding Region Coverage

1x: 99.3%
3x: 98.6%
10x: 97.3%
20x: 95.1%

Validation Efficiency

MGI Phenotype

FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes an inner dynein arm heavy chain that provides structural support between the radial spokes and the outer doublet of the sperm tail. Naturally occurring mutations in this gene are associated with primary ciliary dyskinesia and multiple morphological anomalies of the flagella that result in asthenozoospermia and male infertility. Mice with a homozygous knockout of the orthologous gene are viable but have reduced sperm motility and are infertile. [provided by RefSeq, Feb 2017]
PHENOTYPE: Homozygous mutants are male sterile, and show impaired ciliary and flagellar motility that is also observed in the tracheal cilia. [provided by MGI curators]

Allele List at MGI

Other mutations in this stock

Total: 38 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Abca7	T	C	10: 79,838,367 (GRCm39)	L547P	probably damaging	Het
Arhgap29	A	C	3: 121,784,658 (GRCm39)	D195A	probably damaging	Het
Atad3a	A	T	4: 155,835,976 (GRCm39)	I274N	probably damaging	Het
Ccdc12	G	T	9: 110,485,699 (GRCm39)	K23N	possibly damaging	Het
Ccpg1	A	G	9: 72,920,388 (GRCm39)	T668A	probably benign	Het
Cdc34b	T	C	11: 94,632,998 (GRCm39)	I66T	probably benign	Het
Fam91a1	A	C	15: 58,302,512 (GRCm39)	N284T	probably damaging	Het
Gbp2b	A	T	3: 142,314,040 (GRCm39)	E440V	probably benign	Het
Gm5134	T	C	10: 75,831,670 (GRCm39)	S370P	probably damaging	Het
Hmcn2	G	A	2: 31,309,947 (GRCm39)	A3238T	probably benign	Het
Hmg20a	A	G	9: 56,384,584 (GRCm39)	E118G	possibly damaging	Het
Itprid2	T	C	2: 79,475,267 (GRCm39)	S409P	probably benign	Het
Kdm5a	T	A	6: 120,383,601 (GRCm39)	F781I	possibly damaging	Het
Klk14	G	A	7: 43,341,501 (GRCm39)	C51Y	probably damaging	Het
Kmt2d	A	G	15: 98,737,181 (GRCm39)		probably benign	Het
Lrp1b	T	C	2: 41,298,971 (GRCm39)	T857A	probably benign	Het
Mucl2	T	A	15: 103,927,840 (GRCm39)	N39I	probably damaging	Het
Myl6	A	G	10: 128,328,566 (GRCm39)	I27T	possibly damaging	Het
Ndor1	A	T	2: 25,141,765 (GRCm39)		probably null	Het
Nlrp9a	A	G	7: 26,264,354 (GRCm39)	E758G	probably damaging	Het
Or52h7	G	A	7: 104,213,883 (GRCm39)	A152T	probably benign	Het
Or8u8	A	T	2: 86,011,780 (GRCm39)	I225N	probably damaging	Het
Parp3	G	A	9: 106,353,051 (GRCm39)	R42W	probably damaging	Het
Pik3c2g	A	G	6: 139,798,600 (GRCm39)	I495V	probably damaging	Het
Qrfprl	C	A	6: 65,418,260 (GRCm39)	H143N	probably damaging	Het
Sdsl	C	T	5: 120,596,485 (GRCm39)	G310S	probably damaging	Het
Sec24a	A	G	11: 51,614,411 (GRCm39)	L531P	probably damaging	Het
Slc2a12	C	T	10: 22,540,736 (GRCm39)	S197F	probably benign	Het
Snapc1	T	A	12: 74,017,001 (GRCm39)	I213N	probably damaging	Het
Srpk1	A	T	17: 28,813,163 (GRCm39)	I527N	probably damaging	Het
Steap2	G	T	5: 5,723,643 (GRCm39)	Y412*	probably null	Het
Tbk1	A	C	10: 121,399,836 (GRCm39)	Y329*	probably null	Het
Tekt5	T	C	16: 10,176,189 (GRCm39)	E452G	probably damaging	Het
Tmc5	G	T	7: 118,254,178 (GRCm39)	C672F	probably damaging	Het
Trim27	T	C	13: 21,367,987 (GRCm39)	L201S	probably damaging	Het
Vil1	A	C	1: 74,466,724 (GRCm39)	D638A	probably benign	Het
Vmn2r68	TCC	TC	7: 84,870,758 (GRCm39)		probably null	Het
Zfp583	C	T	7: 6,320,610 (GRCm39)	R134H	probably benign	Het

Other mutations in Dnah1

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00090:Dnah1	APN	14	31,009,830 (GRCm39)	missense	probably benign	0.01
IGL00227:Dnah1	APN	14	31,008,853 (GRCm39)	missense	probably damaging	1.00
IGL00491:Dnah1	APN	14	30,983,796 (GRCm39)	missense	probably damaging	1.00
IGL00787:Dnah1	APN	14	31,022,020 (GRCm39)	missense	possibly damaging	0.91
IGL00809:Dnah1	APN	14	31,022,766 (GRCm39)	nonsense	probably null
IGL00911:Dnah1	APN	14	31,026,391 (GRCm39)	splice site	probably null
IGL00949:Dnah1	APN	14	31,029,047 (GRCm39)	missense	probably benign	0.00
IGL00976:Dnah1	APN	14	31,000,095 (GRCm39)	missense	probably damaging	1.00
IGL01484:Dnah1	APN	14	31,021,897 (GRCm39)	missense	probably damaging	0.98
IGL01629:Dnah1	APN	14	31,014,277 (GRCm39)	missense	probably damaging	1.00
IGL01716:Dnah1	APN	14	30,985,335 (GRCm39)	missense	probably benign	0.34
IGL01893:Dnah1	APN	14	30,988,427 (GRCm39)	missense	probably damaging	1.00
IGL01933:Dnah1	APN	14	31,032,872 (GRCm39)	missense	probably benign	0.40
IGL01938:Dnah1	APN	14	31,005,844 (GRCm39)	missense	probably benign
IGL02032:Dnah1	APN	14	30,996,326 (GRCm39)	missense	probably benign
IGL02052:Dnah1	APN	14	30,990,743 (GRCm39)	missense	probably damaging	0.99
IGL02097:Dnah1	APN	14	31,026,958 (GRCm39)	missense	possibly damaging	0.92
IGL02127:Dnah1	APN	14	31,026,885 (GRCm39)	missense	probably benign	0.00
IGL02143:Dnah1	APN	14	31,005,246 (GRCm39)	missense	probably damaging	1.00
IGL02158:Dnah1	APN	14	31,022,924 (GRCm39)	missense	probably benign	0.00
IGL02442:Dnah1	APN	14	31,009,835 (GRCm39)	missense	probably damaging	1.00
IGL02525:Dnah1	APN	14	31,027,790 (GRCm39)	missense	probably benign	0.05
IGL02558:Dnah1	APN	14	30,996,336 (GRCm39)	missense	possibly damaging	0.96
IGL02633:Dnah1	APN	14	31,006,772 (GRCm39)	missense	probably benign	0.05
IGL02720:Dnah1	APN	14	30,984,177 (GRCm39)	missense	probably damaging	0.96
IGL02728:Dnah1	APN	14	31,005,955 (GRCm39)	missense	probably benign	0.44
IGL02738:Dnah1	APN	14	31,014,597 (GRCm39)	missense	probably benign	0.27
IGL02863:Dnah1	APN	14	31,017,250 (GRCm39)	missense	probably damaging	0.99
IGL02944:Dnah1	APN	14	31,022,828 (GRCm39)	missense	possibly damaging	0.88
IGL03110:Dnah1	APN	14	30,988,674 (GRCm39)	missense	probably benign	0.40
IGL03201:Dnah1	APN	14	31,022,906 (GRCm39)	missense	probably benign	0.13
IGL03215:Dnah1	APN	14	30,996,348 (GRCm39)	missense	probably damaging	1.00
IGL03230:Dnah1	APN	14	30,992,023 (GRCm39)	missense	probably damaging	1.00
IGL03248:Dnah1	APN	14	30,991,846 (GRCm39)	missense	probably damaging	1.00
IGL03267:Dnah1	APN	14	31,008,545 (GRCm39)	missense	probably benign	0.00
IGL03299:Dnah1	APN	14	31,037,079 (GRCm39)	nonsense	probably null
IGL03301:Dnah1	APN	14	31,014,649 (GRCm39)	missense	probably damaging	1.00
ergonomic	UTSW	14	31,022,705 (GRCm39)	missense	possibly damaging	0.91
Faraday	UTSW	14	31,032,839 (GRCm39)	missense	probably null	0.05
K3955:Dnah1	UTSW	14	30,988,416 (GRCm39)	missense	probably benign
PIT1430001:Dnah1	UTSW	14	30,984,537 (GRCm39)	missense	probably damaging	1.00
PIT4382001:Dnah1	UTSW	14	31,006,412 (GRCm39)	missense	probably damaging	1.00
R0043:Dnah1	UTSW	14	30,996,362 (GRCm39)	missense	probably damaging	0.97
R0092:Dnah1	UTSW	14	30,993,566 (GRCm39)	missense	probably benign	0.00
R0100:Dnah1	UTSW	14	30,984,109 (GRCm39)	critical splice donor site	probably null
R0100:Dnah1	UTSW	14	30,984,109 (GRCm39)	critical splice donor site	probably null
R0101:Dnah1	UTSW	14	31,005,856 (GRCm39)	missense	probably damaging	1.00
R0119:Dnah1	UTSW	14	30,998,115 (GRCm39)	missense	probably damaging	1.00
R0136:Dnah1	UTSW	14	30,998,115 (GRCm39)	missense	probably damaging	1.00
R0144:Dnah1	UTSW	14	30,989,831 (GRCm39)	splice site	probably benign
R0279:Dnah1	UTSW	14	31,024,332 (GRCm39)	missense	possibly damaging	0.94
R0299:Dnah1	UTSW	14	30,998,115 (GRCm39)	missense	probably damaging	1.00
R0316:Dnah1	UTSW	14	31,000,108 (GRCm39)	missense	probably benign	0.00
R0739:Dnah1	UTSW	14	30,987,872 (GRCm39)	nonsense	probably null
R0789:Dnah1	UTSW	14	31,026,548 (GRCm39)	missense	probably benign
R0826:Dnah1	UTSW	14	31,025,864 (GRCm39)	missense	probably benign	0.02
R1102:Dnah1	UTSW	14	31,018,414 (GRCm39)	nonsense	probably null
R1116:Dnah1	UTSW	14	31,029,824 (GRCm39)	missense	probably benign	0.13
R1229:Dnah1	UTSW	14	31,032,808 (GRCm39)	missense	probably benign	0.11
R1447:Dnah1	UTSW	14	31,028,855 (GRCm39)	missense	probably benign	0.06
R1449:Dnah1	UTSW	14	30,985,908 (GRCm39)	missense	probably damaging	1.00
R1462:Dnah1	UTSW	14	30,990,738 (GRCm39)	splice site	probably benign
R1482:Dnah1	UTSW	14	31,016,831 (GRCm39)	missense	probably damaging	1.00
R1500:Dnah1	UTSW	14	31,038,715 (GRCm39)	missense	probably benign
R1512:Dnah1	UTSW	14	31,014,994 (GRCm39)	missense	probably damaging	1.00
R1591:Dnah1	UTSW	14	30,994,289 (GRCm39)	missense	probably benign	0.01
R1598:Dnah1	UTSW	14	31,023,219 (GRCm39)	missense	probably benign	0.07
R1644:Dnah1	UTSW	14	31,024,249 (GRCm39)	splice site	probably benign
R1672:Dnah1	UTSW	14	30,998,157 (GRCm39)	missense	probably damaging	1.00
R1713:Dnah1	UTSW	14	31,001,139 (GRCm39)	missense	probably damaging	1.00
R1769:Dnah1	UTSW	14	31,032,839 (GRCm39)	missense	probably null	0.05
R1796:Dnah1	UTSW	14	30,983,050 (GRCm39)	missense	probably benign	0.00
R1902:Dnah1	UTSW	14	31,041,716 (GRCm39)	missense	probably damaging	0.99
R1903:Dnah1	UTSW	14	31,041,716 (GRCm39)	missense	probably damaging	0.99
R1905:Dnah1	UTSW	14	30,986,587 (GRCm39)	missense	probably benign	0.06
R1908:Dnah1	UTSW	14	30,984,515 (GRCm39)	missense	probably damaging	1.00
R1972:Dnah1	UTSW	14	30,987,348 (GRCm39)	nonsense	probably null
R1973:Dnah1	UTSW	14	30,987,348 (GRCm39)	nonsense	probably null
R2004:Dnah1	UTSW	14	31,023,813 (GRCm39)	missense	possibly damaging	0.79
R2051:Dnah1	UTSW	14	31,001,080 (GRCm39)	missense	probably damaging	1.00
R2062:Dnah1	UTSW	14	30,993,086 (GRCm39)	missense	probably damaging	1.00
R2240:Dnah1	UTSW	14	31,021,931 (GRCm39)	missense	probably benign	0.00
R2862:Dnah1	UTSW	14	31,006,719 (GRCm39)	missense	probably benign	0.21
R2894:Dnah1	UTSW	14	31,020,718 (GRCm39)	missense	possibly damaging	0.67
R3120:Dnah1	UTSW	14	30,988,779 (GRCm39)	nonsense	probably null
R3410:Dnah1	UTSW	14	30,991,774 (GRCm39)	missense	possibly damaging	0.55
R3411:Dnah1	UTSW	14	30,991,774 (GRCm39)	missense	possibly damaging	0.55
R3435:Dnah1	UTSW	14	31,038,631 (GRCm39)	missense	probably damaging	0.96
R3615:Dnah1	UTSW	14	31,037,105 (GRCm39)	missense	possibly damaging	0.92
R3616:Dnah1	UTSW	14	31,037,105 (GRCm39)	missense	possibly damaging	0.92
R3741:Dnah1	UTSW	14	30,987,424 (GRCm39)	splice site	probably benign
R3805:Dnah1	UTSW	14	31,016,720 (GRCm39)	missense	possibly damaging	0.67
R3894:Dnah1	UTSW	14	31,028,985 (GRCm39)	missense	probably benign
R4007:Dnah1	UTSW	14	31,025,741 (GRCm39)	splice site	probably benign
R4201:Dnah1	UTSW	14	30,984,227 (GRCm39)	missense	probably benign	0.00
R4232:Dnah1	UTSW	14	31,026,873 (GRCm39)	missense	probably benign
R4372:Dnah1	UTSW	14	31,026,879 (GRCm39)	missense	probably damaging	1.00
R4391:Dnah1	UTSW	14	31,016,792 (GRCm39)	missense	probably damaging	1.00
R4423:Dnah1	UTSW	14	31,006,718 (GRCm39)	missense	probably benign	0.00
R4526:Dnah1	UTSW	14	31,007,955 (GRCm39)	missense	probably benign	0.05
R4650:Dnah1	UTSW	14	31,006,844 (GRCm39)	splice site	probably null
R4723:Dnah1	UTSW	14	30,994,899 (GRCm39)	missense	probably damaging	1.00
R4748:Dnah1	UTSW	14	31,041,902 (GRCm39)	missense	probably benign
R4783:Dnah1	UTSW	14	30,985,436 (GRCm39)	missense	probably damaging	1.00
R4784:Dnah1	UTSW	14	30,985,436 (GRCm39)	missense	probably damaging	1.00
R4785:Dnah1	UTSW	14	30,985,436 (GRCm39)	missense	probably damaging	1.00
R4843:Dnah1	UTSW	14	30,986,920 (GRCm39)	missense	probably damaging	1.00
R4879:Dnah1	UTSW	14	31,022,705 (GRCm39)	missense	possibly damaging	0.91
R4897:Dnah1	UTSW	14	30,989,496 (GRCm39)	missense	probably damaging	1.00
R4911:Dnah1	UTSW	14	31,017,280 (GRCm39)	missense	probably damaging	1.00
R4985:Dnah1	UTSW	14	31,008,855 (GRCm39)	missense	probably null	1.00
R5070:Dnah1	UTSW	14	31,004,375 (GRCm39)	missense	probably benign	0.05
R5128:Dnah1	UTSW	14	31,018,152 (GRCm39)	splice site	probably null
R5409:Dnah1	UTSW	14	30,985,212 (GRCm39)	missense	probably damaging	1.00
R5436:Dnah1	UTSW	14	31,038,704 (GRCm39)	missense	probably benign
R5481:Dnah1	UTSW	14	31,030,828 (GRCm39)	missense	possibly damaging	0.55
R5550:Dnah1	UTSW	14	31,038,665 (GRCm39)	missense	probably benign	0.00
R5555:Dnah1	UTSW	14	31,012,776 (GRCm39)	missense	probably damaging	0.99
R5566:Dnah1	UTSW	14	30,996,323 (GRCm39)	missense	probably benign	0.35
R5623:Dnah1	UTSW	14	31,007,980 (GRCm39)	missense	possibly damaging	0.62
R5701:Dnah1	UTSW	14	30,996,001 (GRCm39)	missense	probably damaging	1.00
R5751:Dnah1	UTSW	14	31,032,863 (GRCm39)	missense	probably benign	0.00
R5823:Dnah1	UTSW	14	30,988,375 (GRCm39)	missense	possibly damaging	0.92
R6030:Dnah1	UTSW	14	30,989,984 (GRCm39)	missense	probably damaging	1.00
R6030:Dnah1	UTSW	14	30,989,984 (GRCm39)	missense	probably damaging	1.00
R6090:Dnah1	UTSW	14	30,991,382 (GRCm39)	missense	possibly damaging	0.83
R6139:Dnah1	UTSW	14	31,007,984 (GRCm39)	missense	probably benign	0.02
R6145:Dnah1	UTSW	14	31,022,927 (GRCm39)	missense	probably benign	0.07
R6306:Dnah1	UTSW	14	31,026,544 (GRCm39)	missense	probably damaging	0.97
R6376:Dnah1	UTSW	14	30,997,565 (GRCm39)	missense	probably damaging	1.00
R6451:Dnah1	UTSW	14	31,022,765 (GRCm39)	missense	probably benign	0.08
R6549:Dnah1	UTSW	14	30,991,340 (GRCm39)	missense	probably damaging	1.00
R6748:Dnah1	UTSW	14	31,021,945 (GRCm39)	missense	probably damaging	0.99
R6826:Dnah1	UTSW	14	31,008,247 (GRCm39)	missense	probably benign	0.00
R6870:Dnah1	UTSW	14	30,993,018 (GRCm39)	nonsense	probably null
R6932:Dnah1	UTSW	14	31,009,733 (GRCm39)	missense	probably damaging	1.00
R6944:Dnah1	UTSW	14	30,990,861 (GRCm39)	missense	probably damaging	1.00
R7033:Dnah1	UTSW	14	30,986,882 (GRCm39)	missense	probably damaging	1.00
R7078:Dnah1	UTSW	14	31,019,067 (GRCm39)	missense	probably damaging	1.00
R7133:Dnah1	UTSW	14	31,008,033 (GRCm39)	missense	probably benign
R7136:Dnah1	UTSW	14	31,020,613 (GRCm39)	missense	probably damaging	1.00
R7203:Dnah1	UTSW	14	30,996,339 (GRCm39)	missense	probably benign
R7241:Dnah1	UTSW	14	30,986,896 (GRCm39)	missense	probably benign	0.00
R7260:Dnah1	UTSW	14	30,991,343 (GRCm39)	missense	probably damaging	1.00
R7264:Dnah1	UTSW	14	30,991,851 (GRCm39)	missense	probably benign
R7291:Dnah1	UTSW	14	31,020,662 (GRCm39)	missense	probably damaging	1.00
R7293:Dnah1	UTSW	14	31,009,820 (GRCm39)	missense	probably damaging	1.00
R7300:Dnah1	UTSW	14	30,991,798 (GRCm39)	missense	probably benign	0.05
R7319:Dnah1	UTSW	14	31,018,551 (GRCm39)	missense	probably benign	0.02
R7323:Dnah1	UTSW	14	31,020,664 (GRCm39)	missense	probably damaging	1.00
R7472:Dnah1	UTSW	14	31,022,748 (GRCm39)	missense	possibly damaging	0.80
R7472:Dnah1	UTSW	14	30,983,547 (GRCm39)	missense	probably damaging	1.00
R7499:Dnah1	UTSW	14	31,037,079 (GRCm39)	nonsense	probably null
R7526:Dnah1	UTSW	14	31,009,833 (GRCm39)	missense	possibly damaging	0.49
R7560:Dnah1	UTSW	14	31,026,940 (GRCm39)	missense	probably benign
R7574:Dnah1	UTSW	14	31,041,865 (GRCm39)	missense	probably benign	0.00
R7617:Dnah1	UTSW	14	31,006,739 (GRCm39)	missense	possibly damaging	0.80
R7620:Dnah1	UTSW	14	31,025,863 (GRCm39)	missense	possibly damaging	0.47
R7692:Dnah1	UTSW	14	31,014,295 (GRCm39)	missense	probably benign	0.00
R7702:Dnah1	UTSW	14	31,032,866 (GRCm39)	missense	probably benign
R7786:Dnah1	UTSW	14	30,984,478 (GRCm39)	missense	probably damaging	1.00
R7984:Dnah1	UTSW	14	30,989,772 (GRCm39)	missense	probably damaging	1.00
R8002:Dnah1	UTSW	14	31,020,679 (GRCm39)	missense	probably damaging	1.00
R8022:Dnah1	UTSW	14	30,986,971 (GRCm39)	missense	probably damaging	1.00
R8032:Dnah1	UTSW	14	30,993,505 (GRCm39)	missense	probably damaging	1.00
R8099:Dnah1	UTSW	14	31,024,321 (GRCm39)	missense	probably benign	0.00
R8171:Dnah1	UTSW	14	31,019,067 (GRCm39)	missense	probably damaging	1.00
R8263:Dnah1	UTSW	14	31,015,134 (GRCm39)	missense	probably damaging	1.00
R8274:Dnah1	UTSW	14	31,017,531 (GRCm39)	missense	probably benign	0.00
R8345:Dnah1	UTSW	14	30,986,551 (GRCm39)	missense	probably damaging	1.00
R8348:Dnah1	UTSW	14	31,015,682 (GRCm39)	missense	probably damaging	1.00
R8353:Dnah1	UTSW	14	31,005,159 (GRCm39)	missense	probably benign
R8356:Dnah1	UTSW	14	30,994,972 (GRCm39)	missense	probably benign	0.00
R8376:Dnah1	UTSW	14	31,023,303 (GRCm39)	missense	probably damaging	1.00
R8448:Dnah1	UTSW	14	31,015,682 (GRCm39)	missense	probably damaging	1.00
R8461:Dnah1	UTSW	14	31,027,915 (GRCm39)	missense	probably benign	0.00
R8534:Dnah1	UTSW	14	31,023,805 (GRCm39)	missense	probably benign	0.16
R8544:Dnah1	UTSW	14	30,990,861 (GRCm39)	missense	probably damaging	1.00
R8679:Dnah1	UTSW	14	30,989,767 (GRCm39)	missense	possibly damaging	0.77
R8716:Dnah1	UTSW	14	30,989,941 (GRCm39)	critical splice donor site	probably benign
R8750:Dnah1	UTSW	14	31,026,924 (GRCm39)	missense	probably benign	0.30
R8790:Dnah1	UTSW	14	31,018,232 (GRCm39)	missense	possibly damaging	0.89
R8808:Dnah1	UTSW	14	31,008,771 (GRCm39)	missense	probably benign
R8821:Dnah1	UTSW	14	31,018,455 (GRCm39)	missense	probably benign
R8887:Dnah1	UTSW	14	31,032,997 (GRCm39)	missense	probably damaging	1.00
R8948:Dnah1	UTSW	14	31,012,396 (GRCm39)	missense	probably damaging	1.00
R8950:Dnah1	UTSW	14	31,012,396 (GRCm39)	missense	probably damaging	1.00
R8955:Dnah1	UTSW	14	31,007,950 (GRCm39)	missense	probably benign
R8987:Dnah1	UTSW	14	31,033,704 (GRCm39)	missense	possibly damaging	0.93
R8998:Dnah1	UTSW	14	31,018,235 (GRCm39)	missense	probably benign	0.12
R8999:Dnah1	UTSW	14	31,018,235 (GRCm39)	missense	probably benign	0.12
R9015:Dnah1	UTSW	14	30,986,316 (GRCm39)	missense	probably damaging	0.96
R9031:Dnah1	UTSW	14	31,001,128 (GRCm39)	missense	probably benign
R9088:Dnah1	UTSW	14	30,987,970 (GRCm39)	missense	probably benign	0.04
R9096:Dnah1	UTSW	14	30,983,027 (GRCm39)	missense	probably damaging	0.99
R9117:Dnah1	UTSW	14	31,033,581 (GRCm39)	splice site	probably benign
R9157:Dnah1	UTSW	14	30,987,970 (GRCm39)	missense	probably damaging	0.97
R9296:Dnah1	UTSW	14	30,996,011 (GRCm39)	critical splice acceptor site	probably null
R9313:Dnah1	UTSW	14	30,987,970 (GRCm39)	missense	probably damaging	0.97
R9325:Dnah1	UTSW	14	30,998,160 (GRCm39)	missense	possibly damaging	0.69
R9352:Dnah1	UTSW	14	31,038,620 (GRCm39)	missense	probably benign	0.00
R9411:Dnah1	UTSW	14	31,018,256 (GRCm39)	missense	probably damaging	1.00
R9429:Dnah1	UTSW	14	30,997,499 (GRCm39)	nonsense	probably null
R9452:Dnah1	UTSW	14	31,018,448 (GRCm39)	missense	probably benign	0.35
R9562:Dnah1	UTSW	14	30,986,394 (GRCm39)	missense	probably damaging	1.00
R9565:Dnah1	UTSW	14	30,986,394 (GRCm39)	missense	probably damaging	1.00
R9616:Dnah1	UTSW	14	31,026,400 (GRCm39)	missense	probably null	0.20
R9621:Dnah1	UTSW	14	31,016,772 (GRCm39)	missense	probably damaging	1.00
R9677:Dnah1	UTSW	14	31,029,821 (GRCm39)	missense	probably benign	0.00
R9723:Dnah1	UTSW	14	30,987,946 (GRCm39)	missense	probably damaging	1.00
R9758:Dnah1	UTSW	14	30,985,395 (GRCm39)	missense	probably damaging	0.98
RF006:Dnah1	UTSW	14	31,029,832 (GRCm39)	missense	probably benign	0.08
Z1088:Dnah1	UTSW	14	31,026,768 (GRCm39)	missense	probably benign	0.17

Predicted Primers

PCR Primer
(F):5'- AGAGGGAAATGGCCTCTGCTAG -3'
(R):5'- GCCTAAGGCTATGGAATAGGTG -3'

Sequencing Primer
(F):5'- CCTCTGCTAGGCTACATTAGGG -3'
(R):5'- CTATGGAATAGGTGCTGGGGCC -3'

Posted On

2014-10-02