Mutagenetix > Incidental Mutation

Incidental Mutation 'R2201:Zfp638'

238654

Institutional Source

Beutler Lab

Gene Symbol

Zfp638

Ensembl Gene

ENSMUSG00000030016

Gene Name

zinc finger protein 638

Synonyms

Np220, Zfml

MMRRC Submission

040203-MU

Accession Numbers

Essential gene?

Probably essential (E-score: 0.862) question?

Stock #

R2201 (G1)

Quality Score

225

Status

Validated

Chromosome

Chromosomal Location

83844050-83963855 bp(+) (GRCm39)

Type of Mutation

missense

DNA Base Change (assembly)

G to C at 83906500 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Aspartic acid to Histidine at position 222 (D222H)

Ref Sequence

ENSEMBL: ENSMUSP00000144989 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000032088] [ENSMUST00000113835] [ENSMUST00000113836] [ENSMUST00000203273] [ENSMUST00000203324] [ENSMUST00000203455] [ENSMUST00000203891] [ENSMUST00000204751] [ENSMUST00000204202] [ENSMUST00000204415]

AlphaFold

no structure available at present

Predicted Effect

probably damaging
Transcript: ENSMUST00000032088
AA Change: D222H

PolyPhen 2 Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)

SMART Domains

Protein: ENSMUSP00000032088
Gene: ENSMUSG00000030016
AA Change: D222H

Domain	Start	End	E-Value	Type
low complexity region	16	35	N/A	INTRINSIC
low complexity region	308	324	N/A	INTRINSIC
ZnF_U1	421	455	5.93e0	SMART
ZnF_C2H2	424	448	1.36e1	SMART
low complexity region	482	523	N/A	INTRINSIC
low complexity region	531	555	N/A	INTRINSIC
low complexity region	618	631	N/A	INTRINSIC
RRM	677	747	2.04e-6	SMART
low complexity region	749	763	N/A	INTRINSIC
low complexity region	781	802	N/A	INTRINSIC
RRM	903	972	9.04e-3	SMART
Blast:RRM_2	1007	1075	4e-25	BLAST
low complexity region	1118	1132	N/A	INTRINSIC
low complexity region	1399	1412	N/A	INTRINSIC
low complexity region	1512	1526	N/A	INTRINSIC
low complexity region	1761	1771	N/A	INTRINSIC
ZnF_U1	1873	1907	2.84e-8	SMART
ZnF_C2H2	1876	1900	2.14e0	SMART

Predicted Effect

probably damaging
Transcript: ENSMUST00000113835
AA Change: D222H

PolyPhen 2 Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)

SMART Domains

Protein: ENSMUSP00000109466
Gene: ENSMUSG00000030016
AA Change: D222H

Domain	Start	End	E-Value	Type
low complexity region	16	35	N/A	INTRINSIC
low complexity region	308	324	N/A	INTRINSIC
ZnF_U1	421	455	5.93e0	SMART
ZnF_C2H2	424	448	1.36e1	SMART
low complexity region	482	523	N/A	INTRINSIC
low complexity region	531	555	N/A	INTRINSIC
low complexity region	618	631	N/A	INTRINSIC
RRM	677	747	2.04e-6	SMART
low complexity region	749	763	N/A	INTRINSIC
low complexity region	781	802	N/A	INTRINSIC
RRM	880	949	9.04e-3	SMART
Blast:RRM_2	984	1052	2e-25	BLAST
low complexity region	1095	1109	N/A	INTRINSIC
ZnF_U1	1218	1252	2.84e-8	SMART
ZnF_C2H2	1221	1245	2.14e0	SMART

Predicted Effect

probably damaging
Transcript: ENSMUST00000113836
AA Change: D222H

PolyPhen 2 Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)

SMART Domains

Protein: ENSMUSP00000109467
Gene: ENSMUSG00000030016
AA Change: D222H

Domain	Start	End	E-Value	Type
low complexity region	16	35	N/A	INTRINSIC
low complexity region	308	324	N/A	INTRINSIC
ZnF_U1	421	455	5.93e0	SMART
ZnF_C2H2	424	448	1.36e1	SMART
low complexity region	482	523	N/A	INTRINSIC
low complexity region	531	555	N/A	INTRINSIC
low complexity region	618	631	N/A	INTRINSIC
RRM	677	747	2.04e-6	SMART
low complexity region	749	763	N/A	INTRINSIC
low complexity region	781	802	N/A	INTRINSIC
RRM	903	972	9.04e-3	SMART
Blast:RRM_2	1007	1075	2e-25	BLAST
low complexity region	1118	1132	N/A	INTRINSIC
ZnF_U1	1222	1256	2.84e-8	SMART
ZnF_C2H2	1225	1249	2.14e0	SMART

Predicted Effect

probably benign
Transcript: ENSMUST00000203273

Predicted Effect

probably damaging
Transcript: ENSMUST00000203324
AA Change: D222H

PolyPhen 2 Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)

SMART Domains

Protein: ENSMUSP00000145124
Gene: ENSMUSG00000030016
AA Change: D222H

Domain	Start	End	E-Value	Type
low complexity region	16	35	N/A	INTRINSIC
low complexity region	308	324	N/A	INTRINSIC
ZnF_U1	421	455	3.5e-2	SMART
ZnF_C2H2	424	448	5.9e-2	SMART
low complexity region	482	523	N/A	INTRINSIC
low complexity region	531	555	N/A	INTRINSIC
low complexity region	618	631	N/A	INTRINSIC
RRM	677	747	9.1e-9	SMART
low complexity region	749	763	N/A	INTRINSIC
low complexity region	781	802	N/A	INTRINSIC
RRM	903	972	3.9e-5	SMART
Blast:RRM_2	1007	1075	2e-25	BLAST
low complexity region	1118	1132	N/A	INTRINSIC
ZnF_U1	1220	1254	1.7e-10	SMART
ZnF_C2H2	1223	1247	8.9e-3	SMART

Predicted Effect

probably damaging
Transcript: ENSMUST00000203455
AA Change: D222H

PolyPhen 2 Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)

SMART Domains

Protein: ENSMUSP00000145047
Gene: ENSMUSG00000030016
AA Change: D222H

Domain	Start	End	E-Value	Type
low complexity region	16	35	N/A	INTRINSIC
low complexity region	308	324	N/A	INTRINSIC
ZnF_C2H2	424	448	1.36e1	SMART
low complexity region	482	523	N/A	INTRINSIC
low complexity region	531	555	N/A	INTRINSIC
low complexity region	618	631	N/A	INTRINSIC
RRM	677	747	2.04e-6	SMART
low complexity region	749	763	N/A	INTRINSIC
low complexity region	781	802	N/A	INTRINSIC
internal_repeat_1	819	891	3.29e-10	PROSPERO

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000203808

Predicted Effect

probably damaging
Transcript: ENSMUST00000203891
AA Change: D222H

PolyPhen 2 Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)

SMART Domains

Protein: ENSMUSP00000144939
Gene: ENSMUSG00000030016
AA Change: D222H

Domain	Start	End	E-Value	Type
low complexity region	16	35	N/A	INTRINSIC
low complexity region	308	324	N/A	INTRINSIC
ZnF_U1	421	455	3.5e-2	SMART
ZnF_C2H2	424	448	5.9e-2	SMART
low complexity region	482	523	N/A	INTRINSIC
low complexity region	531	555	N/A	INTRINSIC
low complexity region	618	631	N/A	INTRINSIC
RRM	677	747	9.1e-9	SMART
low complexity region	749	763	N/A	INTRINSIC
low complexity region	781	802	N/A	INTRINSIC
RRM	903	972	3.9e-5	SMART
Blast:RRM_2	1007	1075	2e-25	BLAST
low complexity region	1118	1132	N/A	INTRINSIC
ZnF_U1	1186	1220	1.7e-10	SMART
ZnF_C2H2	1189	1213	8.9e-3	SMART

Predicted Effect

probably damaging
Transcript: ENSMUST00000204751
AA Change: D222H

PolyPhen 2 Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)

SMART Domains

Protein: ENSMUSP00000144989
Gene: ENSMUSG00000030016
AA Change: D222H

Domain	Start	End	E-Value	Type
low complexity region	16	35	N/A	INTRINSIC
low complexity region	308	324	N/A	INTRINSIC
ZnF_U1	421	455	5.93e0	SMART
ZnF_C2H2	424	448	1.36e1	SMART
low complexity region	482	523	N/A	INTRINSIC
low complexity region	531	555	N/A	INTRINSIC
low complexity region	618	631	N/A	INTRINSIC
RRM	677	747	2.04e-6	SMART
low complexity region	749	763	N/A	INTRINSIC
low complexity region	781	802	N/A	INTRINSIC
RRM	903	972	9.04e-3	SMART
Blast:RRM_2	1007	1075	4e-25	BLAST
low complexity region	1118	1132	N/A	INTRINSIC
low complexity region	1399	1412	N/A	INTRINSIC
low complexity region	1512	1526	N/A	INTRINSIC
low complexity region	1761	1771	N/A	INTRINSIC
ZnF_U1	1873	1907	2.84e-8	SMART
ZnF_C2H2	1876	1900	2.14e0	SMART

Predicted Effect

probably damaging
Transcript: ENSMUST00000204202
AA Change: D222H

PolyPhen 2 Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)

SMART Domains

Protein: ENSMUSP00000145170
Gene: ENSMUSG00000030016
AA Change: D222H

Domain	Start	End	E-Value	Type
low complexity region	16	35	N/A	INTRINSIC
low complexity region	308	324	N/A	INTRINSIC
ZnF_C2H2	424	448	5.9e-2	SMART
low complexity region	482	523	N/A	INTRINSIC
low complexity region	531	555	N/A	INTRINSIC
low complexity region	618	631	N/A	INTRINSIC
RRM	677	747	9.1e-9	SMART
low complexity region	749	763	N/A	INTRINSIC
low complexity region	781	802	N/A	INTRINSIC

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000204110

Predicted Effect

probably benign
Transcript: ENSMUST00000204415

SMART Domains

Protein: ENSMUSP00000145513
Gene: ENSMUSG00000030016

Domain	Start	End	E-Value	Type
low complexity region	2	21	N/A	INTRINSIC
low complexity region	112	131	N/A	INTRINSIC

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000204580

Meta Mutation Damage Score

0.2362

Coding Region Coverage

1x: 99.2%
3x: 98.7%
10x: 97.5%
20x: 95.9%

Validation Efficiency

98% (59/60)

MGI Phenotype

FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] The protein encoded by this gene is a nucleoplasmic protein. It binds cytidine-rich sequences in double-stranded DNA. This protein has three types of domains: MH1, MH2 (repeated three times) and MH3. It is associated with packaging, transferring, or processing transcripts. Multiple alternatively spliced transcript variants have been found for this gene, but the biological validity of some variants has not been determined. [provided by RefSeq, Jul 2008]

Allele List at MGI

Other mutations in this stock

Total: 61 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
A2ml1	A	T	6: 128,524,268 (GRCm39)	N1121K	probably null	Het
Actr10	A	G	12: 71,006,795 (GRCm39)	N351D	probably damaging	Het
Adcy7	G	A	8: 89,044,606 (GRCm39)	A500T	probably damaging	Het
Ankrd35	T	C	3: 96,586,564 (GRCm39)	I80T	possibly damaging	Het
Arap2	G	A	5: 62,864,028 (GRCm39)	T532I	probably damaging	Het
Bag3	AAAGG	AAAGGAAGG	7: 128,147,493 (GRCm39)		probably null	Het
Cc2d2a	T	C	5: 43,841,375 (GRCm39)		probably benign	Het
Cep85l	A	T	10: 53,224,827 (GRCm39)	M254K	probably benign	Het
Clic4	A	G	4: 134,950,850 (GRCm39)	S114P	probably damaging	Het
Ctsj	T	C	13: 61,150,363 (GRCm39)	Y213C	probably damaging	Het
Ddx28	A	G	8: 106,737,206 (GRCm39)	V284A	probably damaging	Het
Dnase2b	T	A	3: 146,290,443 (GRCm39)	D176V	probably damaging	Het
Dsg2	T	A	18: 20,729,111 (GRCm39)	N663K	probably damaging	Het
Dst	T	A	1: 34,235,002 (GRCm39)	S3694T	possibly damaging	Het
Emilin1	T	C	5: 31,073,036 (GRCm39)	S158P	probably benign	Het
Eng	T	C	2: 32,563,752 (GRCm39)		probably benign	Het
Entrep2	T	A	7: 64,409,141 (GRCm39)	M418L	probably benign	Het
Fdxr	C	A	11: 115,161,208 (GRCm39)	V223L	probably benign	Het
Fhip1b	T	C	7: 105,037,398 (GRCm39)	N395S	probably damaging	Het
Frem2	T	A	3: 53,423,994 (GRCm39)	M3148L	probably benign	Het
Hip1	A	T	5: 135,460,584 (GRCm39)	D114E	probably benign	Het
Itga9	T	C	9: 118,706,183 (GRCm39)		probably benign	Het
Kcnt2	T	A	1: 140,437,179 (GRCm39)	N487K	probably damaging	Het
Krt6a	A	G	15: 101,601,606 (GRCm39)	F172L	probably benign	Het
Megf8	C	T	7: 25,040,170 (GRCm39)	R1034W	probably damaging	Het
Muc6	C	T	7: 141,236,075 (GRCm39)	D451N	probably damaging	Het
Myo5a	A	G	9: 75,125,225 (GRCm39)	T1838A	possibly damaging	Het
N4bp2l2	A	T	5: 150,585,073 (GRCm39)	D302E	probably damaging	Het
Nbeal2	T	A	9: 110,459,318 (GRCm39)	I1930F	probably benign	Het
Nhsl3	A	G	4: 129,116,432 (GRCm39)	V732A	probably benign	Het
Npas4	A	T	19: 5,037,392 (GRCm39)	Y301N	probably benign	Het
Nt5m	A	G	11: 59,766,741 (GRCm39)	K211E	probably benign	Het
Pfn4	A	G	12: 4,824,382 (GRCm39)		probably null	Het
Pfpl	A	C	19: 12,407,843 (GRCm39)	D698A	probably benign	Het
Pias1	G	T	9: 62,859,137 (GRCm39)	H124N	possibly damaging	Het
Pja2	A	T	17: 64,618,162 (GRCm39)		probably benign	Het
Polr3e	T	C	7: 120,531,465 (GRCm39)	Y185H	probably benign	Het
Pomc	T	C	12: 4,010,275 (GRCm39)	L172S	probably benign	Het
Rapgef4	A	G	2: 71,875,533 (GRCm39)	T129A	probably damaging	Het
Reep1	T	C	6: 71,750,278 (GRCm39)	S97P	probably damaging	Het
Rttn	T	A	18: 89,029,067 (GRCm39)	I595N	possibly damaging	Het
Sap30	T	C	8: 57,938,506 (GRCm39)		probably null	Het
Slc1a7	T	C	4: 107,850,203 (GRCm39)	Y105H	probably damaging	Het
Slc5a5	C	T	8: 71,345,102 (GRCm39)	M68I	probably damaging	Het
Stab2	T	A	10: 86,776,503 (GRCm39)	Y791F	probably benign	Het
Tdrd1	C	A	19: 56,847,094 (GRCm39)	H912N	probably benign	Het
Tdrd1	C	A	19: 56,847,093 (GRCm39)	S911R	probably benign	Het
Tgm7	A	T	2: 120,929,062 (GRCm39)	F278Y	probably damaging	Het
Tln2	T	C	9: 67,283,039 (GRCm39)	T310A	probably damaging	Het
Tmem256	T	C	11: 69,730,271 (GRCm39)	I93T	probably benign	Het
Trpm2	G	A	10: 77,756,305 (GRCm39)	Q1172*	probably null	Het
Ttll8	A	G	15: 88,818,156 (GRCm39)	V173A	possibly damaging	Het
Ubr5	T	C	15: 38,002,543 (GRCm39)	S1497G	possibly damaging	Het
Ubr7	G	A	12: 102,727,764 (GRCm39)		probably null	Het
Vmn1r37	T	A	6: 66,708,878 (GRCm39)	M1K	probably null	Het
Vmn2r14	A	G	5: 109,366,698 (GRCm39)		probably null	Het
Vmn2r72	T	C	7: 85,387,444 (GRCm39)	I707V	probably benign	Het
Vps8	A	G	16: 21,395,507 (GRCm39)	R1266G	probably damaging	Het
Wdr87-ps	T	A	7: 29,235,950 (GRCm39)		noncoding transcript	Het
Zfhx4	A	G	3: 5,307,349 (GRCm39)	N192D	probably damaging	Het
Zscan29	A	C	2: 120,999,883 (GRCm39)	V106G	probably damaging	Het

Other mutations in Zfp638

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00335:Zfp638	APN	6	83,956,700 (GRCm39)	missense	probably damaging	1.00
IGL00514:Zfp638	APN	6	83,933,680 (GRCm39)	missense	probably damaging	1.00
IGL00705:Zfp638	APN	6	83,954,112 (GRCm39)	missense	probably damaging	1.00
IGL00785:Zfp638	APN	6	83,906,146 (GRCm39)	missense	probably damaging	1.00
IGL01068:Zfp638	APN	6	83,911,976 (GRCm39)	missense	probably damaging	1.00
IGL01084:Zfp638	APN	6	83,921,780 (GRCm39)	missense	probably benign	0.01
IGL01570:Zfp638	APN	6	83,924,829 (GRCm39)	missense	probably damaging	1.00
IGL01758:Zfp638	APN	6	83,956,508 (GRCm39)	missense	probably damaging	0.96
IGL02345:Zfp638	APN	6	83,961,857 (GRCm39)	missense	probably damaging	1.00
IGL02939:Zfp638	APN	6	83,946,214 (GRCm39)	missense	probably damaging	0.98
IGL03007:Zfp638	APN	6	83,961,866 (GRCm39)	missense	probably damaging	1.00
IGL03118:Zfp638	APN	6	83,912,000 (GRCm39)	splice site	probably benign
IGL03135:Zfp638	APN	6	83,919,857 (GRCm39)	missense	probably damaging	1.00
IGL03264:Zfp638	APN	6	83,923,229 (GRCm39)	missense	probably benign	0.04
R0190:Zfp638	UTSW	6	83,905,946 (GRCm39)	missense	probably damaging	1.00
R0200:Zfp638	UTSW	6	83,944,336 (GRCm39)	missense	probably damaging	1.00
R0766:Zfp638	UTSW	6	83,906,023 (GRCm39)	missense	probably damaging	1.00
R0801:Zfp638	UTSW	6	83,949,220 (GRCm39)	unclassified	probably benign
R0938:Zfp638	UTSW	6	83,961,023 (GRCm39)	missense	probably benign	0.16
R1312:Zfp638	UTSW	6	83,906,023 (GRCm39)	missense	probably damaging	1.00
R1458:Zfp638	UTSW	6	83,921,638 (GRCm39)	missense	probably damaging	1.00
R1584:Zfp638	UTSW	6	83,955,047 (GRCm39)	splice site	probably null
R1634:Zfp638	UTSW	6	83,956,894 (GRCm39)	splice site	probably null
R1651:Zfp638	UTSW	6	83,931,719 (GRCm39)	missense	probably benign	0.00
R2079:Zfp638	UTSW	6	83,930,371 (GRCm39)	critical splice donor site	probably null
R2134:Zfp638	UTSW	6	83,905,964 (GRCm39)	missense	probably damaging	1.00
R2142:Zfp638	UTSW	6	83,963,578 (GRCm39)	missense	probably damaging	1.00
R2422:Zfp638	UTSW	6	83,943,421 (GRCm39)	splice site	probably benign
R4353:Zfp638	UTSW	6	83,961,041 (GRCm39)	missense	probably damaging	0.97
R4681:Zfp638	UTSW	6	83,958,719 (GRCm39)	missense	possibly damaging	0.50
R4716:Zfp638	UTSW	6	83,956,544 (GRCm39)	nonsense	probably null
R4807:Zfp638	UTSW	6	83,920,040 (GRCm39)	missense	probably damaging	1.00
R4850:Zfp638	UTSW	6	83,956,457 (GRCm39)	missense	possibly damaging	0.92
R5079:Zfp638	UTSW	6	83,906,438 (GRCm39)	missense	probably benign	0.03
R5236:Zfp638	UTSW	6	83,953,557 (GRCm39)	nonsense	probably null
R5323:Zfp638	UTSW	6	83,939,076 (GRCm39)	missense	probably damaging	0.96
R5426:Zfp638	UTSW	6	83,953,396 (GRCm39)	missense	probably damaging	1.00
R5557:Zfp638	UTSW	6	83,944,345 (GRCm39)	missense	probably damaging	1.00
R5570:Zfp638	UTSW	6	83,956,170 (GRCm39)	missense	probably damaging	1.00
R5614:Zfp638	UTSW	6	83,906,623 (GRCm39)	missense	probably damaging	1.00
R5662:Zfp638	UTSW	6	83,920,111 (GRCm39)	missense	probably damaging	0.97
R5685:Zfp638	UTSW	6	83,906,969 (GRCm39)	missense	probably damaging	1.00
R5689:Zfp638	UTSW	6	83,906,054 (GRCm39)	missense	probably damaging	1.00
R5783:Zfp638	UTSW	6	83,921,829 (GRCm39)	missense	possibly damaging	0.92
R5856:Zfp638	UTSW	6	83,954,047 (GRCm39)	missense	probably damaging	1.00
R6310:Zfp638	UTSW	6	83,844,212 (GRCm39)	missense	possibly damaging	0.90
R6477:Zfp638	UTSW	6	83,942,560 (GRCm39)	missense	probably damaging	1.00
R6557:Zfp638	UTSW	6	83,907,092 (GRCm39)	missense	probably damaging	1.00
R7084:Zfp638	UTSW	6	83,930,108 (GRCm39)	missense	possibly damaging	0.50
R7101:Zfp638	UTSW	6	83,931,708 (GRCm39)	missense	probably benign	0.00
R7141:Zfp638	UTSW	6	83,844,181 (GRCm39)	missense	unknown
R7368:Zfp638	UTSW	6	83,906,437 (GRCm39)	missense	possibly damaging	0.60
R7402:Zfp638	UTSW	6	83,905,670 (GRCm39)	missense	possibly damaging	0.92
R7455:Zfp638	UTSW	6	83,907,127 (GRCm39)	missense	probably damaging	1.00
R7762:Zfp638	UTSW	6	83,953,254 (GRCm39)	missense	probably damaging	1.00
R7773:Zfp638	UTSW	6	83,956,196 (GRCm39)	missense	probably damaging	1.00
R8090:Zfp638	UTSW	6	83,906,801 (GRCm39)	missense	probably damaging	0.99
R8154:Zfp638	UTSW	6	83,954,391 (GRCm39)	missense	probably damaging	1.00
R8161:Zfp638	UTSW	6	83,906,713 (GRCm39)	missense	possibly damaging	0.85
R8327:Zfp638	UTSW	6	83,905,679 (GRCm39)	missense	probably damaging	0.99
R8384:Zfp638	UTSW	6	83,956,747 (GRCm39)	missense	probably benign	0.28
R8703:Zfp638	UTSW	6	83,954,143 (GRCm39)	missense	probably damaging	0.96
R8738:Zfp638	UTSW	6	83,931,745 (GRCm39)	critical splice donor site	probably null
R8865:Zfp638	UTSW	6	83,954,035 (GRCm39)	missense	possibly damaging	0.91
R8874:Zfp638	UTSW	6	83,946,135 (GRCm39)	missense	probably damaging	1.00
R9080:Zfp638	UTSW	6	83,844,155 (GRCm39)	missense	unknown
R9113:Zfp638	UTSW	6	83,953,894 (GRCm39)	missense	probably damaging	0.96
R9574:Zfp638	UTSW	6	83,956,680 (GRCm39)	missense	probably damaging	1.00
R9661:Zfp638	UTSW	6	83,923,320 (GRCm39)	missense	probably damaging	0.99
R9722:Zfp638	UTSW	6	83,923,301 (GRCm39)	missense	probably damaging	1.00
R9745:Zfp638	UTSW	6	83,921,795 (GRCm39)	missense	probably benign	0.27
Z1088:Zfp638	UTSW	6	83,921,793 (GRCm39)	missense	probably damaging	1.00

Predicted Primers

PCR Primer
(F):5'- TAGCCGCTATCCTGATGAACAG -3'
(R):5'- TTGGTTCCACTCTCAACTGG -3'

Sequencing Primer
(F):5'- TATCCTGATGAACAGCTAACTCCTG -3'
(R):5'- AGACTGACTGGAGGACTCACC -3'

Posted On

2014-10-02