Mutagenetix > Incidental Mutation

Incidental Mutation 'R2326:Gm5600'

244916

Institutional Source

Beutler Lab

Gene Symbol

Gm5600

Ensembl Gene

ENSMUSG00000073862

Gene Name

predicted gene 5600

Synonyms

ENSMUSG00000073862

MMRRC Submission

040317-MU

Accession Numbers

Essential gene?

Probably non essential (E-score: 0.128) question?

Stock #

R2326 (G1)

Quality Score

225

Status

Validated

Chromosome

Chromosomal Location

113305331-113310238 bp(-) (GRCm39)

Type of Mutation

exon

DNA Base Change (assembly)

G to T at 113307041 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Gene Model

predicted gene model for transcript(s):

AlphaFold

no structure available at present

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000098100

SMART Domains

Protein: ENSMUSP00000095704
Gene: ENSMUSG00000073862

Domain	Start	End	E-Value	Type
low complexity region	78	91	N/A	INTRINSIC

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000211589

Meta Mutation Damage Score

0.0869

Coding Region Coverage

1x: 99.2%
3x: 98.6%
10x: 97.3%
20x: 95.0%

Validation Efficiency

100% (31/31)

Allele List at MGI

Other mutations in this stock

Total: 28 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Bglap3	G	C	3: 88,276,819 (GRCm39)		probably benign	Het
Cdh3	A	G	8: 107,237,940 (GRCm39)	T45A	probably benign	Het
Cdyl2	A	G	8: 117,350,537 (GRCm39)	V198A	probably benign	Het
Crygs	C	T	16: 22,624,301 (GRCm39)	G102D	possibly damaging	Het
Cyp7a1	A	T	4: 6,268,396 (GRCm39)	I443K	probably benign	Het
Dazap1	T	A	10: 80,120,067 (GRCm39)	M234K	possibly damaging	Het
Dnmt1	A	T	9: 20,835,442 (GRCm39)		probably benign	Het
Dusp8	A	G	7: 141,643,800 (GRCm39)	Y38H	probably damaging	Het
Ewsr1	A	G	11: 5,041,857 (GRCm39)		probably null	Het
Fem1b	T	C	9: 62,704,285 (GRCm39)	H325R	probably damaging	Het
Flrt3	C	A	2: 140,503,311 (GRCm39)	V106F	possibly damaging	Het
Foxp2	T	A	6: 15,409,938 (GRCm39)	S513T	possibly damaging	Het
Haspin	A	G	11: 73,026,911 (GRCm39)	I726T	probably benign	Het
Lama4	T	A	10: 38,918,563 (GRCm39)		probably null	Het
Lrrc7	A	T	3: 157,876,298 (GRCm39)	H597Q	probably damaging	Het
Mrc2	G	A	11: 105,239,257 (GRCm39)		probably null	Het
Plcb4	C	T	2: 135,781,893 (GRCm39)	T238M	probably damaging	Het
Plekhd1	A	G	12: 80,768,873 (GRCm39)		probably null	Het
Prph	C	G	15: 98,953,163 (GRCm39)		probably benign	Het
Rassf2	C	T	2: 131,842,352 (GRCm39)		probably null	Het
Saal1	A	G	7: 46,342,235 (GRCm39)	F403L	probably benign	Het
Serpina3a	C	T	12: 104,082,758 (GRCm39)	T177I	probably benign	Het
Slc23a2	C	T	2: 131,936,115 (GRCm39)	E52K	possibly damaging	Het
Stab2	T	A	10: 86,790,338 (GRCm39)		probably null	Het
Syne3	T	A	12: 104,935,493 (GRCm39)	E95V	probably damaging	Het
Vmn1r58	G	T	7: 5,413,939 (GRCm39)	T97N	probably damaging	Het
Vmn2r61	T	G	7: 41,916,287 (GRCm39)	L300W	probably damaging	Het
Vps13a	T	C	19: 16,720,421 (GRCm39)	E388G	possibly damaging	Het

Other mutations in Gm5600

Allele	Source	Chr	Coord	Type	Predicted Effect
IGL01896:Gm5600	APN	7	113,307,221 (GRCm39)	exon	noncoding transcript
R0007:Gm5600	UTSW	7	113,307,010 (GRCm39)	exon	noncoding transcript
R5613:Gm5600	UTSW	7	113,307,293 (GRCm39)	exon	noncoding transcript
R5921:Gm5600	UTSW	7	113,307,413 (GRCm39)	exon	noncoding transcript

Predicted Primers

PCR Primer
(F):5'- AACCTATAGCTGCCTCCAGGAC -3'
(R):5'- TAAACTGTGGGCTGCTTTGC -3'

Sequencing Primer
(F):5'- TCCAGGACCAGTGCTTTAGAATC -3'
(R):5'- GAATGCTAGACCTCACCTGAGTCTG -3'

Posted On

2014-10-30