Mutagenetix > Incidental Mutation

Incidental Mutation 'R2420:Tep1'

249235

Institutional Source

Beutler Lab

Gene Symbol

Tep1

Ensembl Gene

ENSMUSG00000006281

Gene Name

telomerase associated protein 1

Synonyms

Tp1

MMRRC Submission

040382-MU

Accession Numbers

Essential gene?

Non essential (E-score: 0.000) question?

Stock #

R2420 (G1)

Quality Score

225

Status

Not validated

Chromosome

Chromosomal Location

51061516-51108017 bp(-) (GRCm39)

Type of Mutation

missense

DNA Base Change (assembly)

T to A at 51071480 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Histidine to Leucine at position 2055 (H2055L)

Ref Sequence

ENSEMBL: ENSMUSP00000006444 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000006444] [ENSMUST00000227526]

AlphaFold

P97499

Predicted Effect

probably benign
Transcript: ENSMUST00000006444
AA Change: H2055L

PolyPhen 2 Score 0.000 (Sensitivity: 1.00; Specificity: 0.00)

SMART Domains

Protein: ENSMUSP00000006444
Gene: ENSMUSG00000006281
AA Change: H2055L

Domain	Start	End	E-Value	Type
Pfam:TEP1_N	1	29	2.8e-20	PFAM
Pfam:TEP1_N	31	59	1.4e-20	PFAM
Pfam:TEP1_N	61	89	3.1e-20	PFAM
Pfam:TEP1_N	91	119	3e-20	PFAM
low complexity region	195	207	N/A	INTRINSIC
low complexity region	211	229	N/A	INTRINSIC
Pfam:TROVE	230	685	3.2e-136	PFAM
Pfam:DUF4062	909	1020	2.4e-22	PFAM
Pfam:NACHT	1171	1346	9.2e-38	PFAM
low complexity region	1393	1405	N/A	INTRINSIC
low complexity region	1622	1641	N/A	INTRINSIC
WD40	1673	1711	2.98e-1	SMART
WD40	1714	1752	5.33e0	SMART
WD40	1755	1794	1.52e-4	SMART
WD40	1797	1835	3.27e-4	SMART
WD40	1838	1877	3.09e-1	SMART
WD40	1880	1919	2.24e-2	SMART
WD40	1925	1962	4.95e0	SMART
WD40	1968	2003	2.29e1	SMART
WD40	2008	2045	1.72e0	SMART
WD40	2058	2097	3.89e-11	SMART
WD40	2103	2142	3.93e-7	SMART
WD40	2145	2182	4.38e-5	SMART
WD40	2184	2232	1.24e0	SMART
WD40	2235	2273	1.14e-3	SMART
WD40	2275	2315	4.46e-1	SMART
Blast:WD40	2316	2353	4e-12	BLAST
WD40	2546	2583	6.79e-2	SMART

Predicted Effect

probably benign
Transcript: ENSMUST00000226430

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000227193

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000227228

Predicted Effect

probably benign
Transcript: ENSMUST00000227526

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000228562

Coding Region Coverage

1x: 99.1%
3x: 98.4%
10x: 96.9%
20x: 93.6%

Validation Efficiency

MGI Phenotype

FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene product is a component of the ribonucleoprotein complex responsible for telomerase activity which catalyzes the addition of new telomeres on the chromosome ends. The telomerase-associated proteins are conserved from ciliates to humans. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016]
PHENOTYPE: Mice homozygous for a disruption in this gene show no obvious phenotype. No changes are seen in telomerase activity or telomere length. [provided by MGI curators]

Allele List at MGI

Other mutations in this stock

Total: 71 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
6820408C15Rik	A	G	2: 152,270,921 (GRCm39)	K48R	probably damaging	Het
Acsm2	T	C	7: 119,162,857 (GRCm39)	F44L	probably damaging	Het
Actr5	T	C	2: 158,478,001 (GRCm39)	F457S	probably damaging	Het
Adamts3	A	G	5: 89,831,034 (GRCm39)	S1007P	probably damaging	Het
Ahnak	C	T	19: 8,986,620 (GRCm39)	P2635S	possibly damaging	Het
Ankrd17	A	T	5: 90,437,179 (GRCm39)	D555E	possibly damaging	Het
Arhgap29	A	G	3: 121,767,629 (GRCm39)	I24V	probably benign	Het
Atxn2	A	T	5: 121,940,142 (GRCm39)		probably null	Het
Birc6	T	A	17: 74,967,609 (GRCm39)	L301Q	probably damaging	Het
Ccdc137	G	A	11: 120,353,090 (GRCm39)		probably null	Het
Ccdc18	A	C	5: 108,376,454 (GRCm39)	E1298D	probably damaging	Het
Chst9	A	T	18: 15,585,341 (GRCm39)	N407K	probably damaging	Het
Cwf19l2	A	G	9: 3,411,341 (GRCm39)	K73E	possibly damaging	Het
Dhcr24	G	T	4: 106,418,291 (GRCm39)		probably benign	Het
Dnajc21	A	G	15: 10,462,021 (GRCm39)	S127P	probably benign	Het
Egln1	T	C	8: 125,674,985 (GRCm39)	N270S	probably benign	Het
Eme1	A	G	11: 94,536,640 (GRCm39)		probably null	Het
Emilin2	A	G	17: 71,581,274 (GRCm39)	I484T	possibly damaging	Het
Entpd2	T	C	2: 25,289,295 (GRCm39)	I259T	probably benign	Het
Fbp1	T	C	13: 63,019,120 (GRCm39)	K24E	probably benign	Het
Fga	A	T	3: 82,940,461 (GRCm39)	N705I	possibly damaging	Het
Gas1	G	T	13: 60,324,744 (GRCm39)		probably benign	Het
Glrb	A	G	3: 80,767,542 (GRCm39)	I226T	probably damaging	Het
Gm17421	T	A	12: 113,333,107 (GRCm39)		noncoding transcript	Het
Gm44501	A	T	17: 40,889,600 (GRCm39)	H38L	possibly damaging	Het
H2-M10.5	A	G	17: 37,085,891 (GRCm39)	I308V	probably benign	Het
Hjurp	GT	GTT	1: 88,194,246 (GRCm39)		probably null	Het
Jcad	T	C	18: 4,675,952 (GRCm39)	M1238T	probably damaging	Het
Kank1	T	C	19: 25,387,821 (GRCm39)	L498S	probably damaging	Het
Krt10	G	A	11: 99,277,933 (GRCm39)	T338I	possibly damaging	Het
Krt13	A	T	11: 100,010,877 (GRCm39)	L159Q	probably benign	Het
Lama1	A	T	17: 68,057,548 (GRCm39)	M541L	probably benign	Het
Lilra6	A	G	7: 3,917,857 (GRCm39)	Y96H	probably damaging	Het
Ltc4s	A	G	11: 50,128,166 (GRCm39)		probably null	Het
Ly6g6e	G	A	17: 35,297,122 (GRCm39)	R121Q	probably benign	Het
Mfn1	A	G	3: 32,623,664 (GRCm39)	I263V	probably benign	Het
Mmaa	T	A	8: 80,008,061 (GRCm39)	R59W	probably damaging	Het
Mug2	C	A	6: 122,060,419 (GRCm39)	T1385K	probably damaging	Het
Mypn	G	T	10: 63,028,648 (GRCm39)	Y138*	probably null	Het
Nav3	A	C	10: 109,699,674 (GRCm39)	S273R	probably damaging	Het
Ndufaf1	T	C	2: 119,486,218 (GRCm39)	E298G	probably damaging	Het
Or10d5	A	G	9: 39,861,824 (GRCm39)	L81P	possibly damaging	Het
Or4c114	T	C	2: 88,905,336 (GRCm39)	Y33C	possibly damaging	Het
Or4k42	T	C	2: 111,319,602 (GRCm39)		probably null	Het
Or5k15	T	C	16: 58,710,328 (GRCm39)	E85G	probably benign	Het
Or5p51	T	C	7: 107,444,025 (GRCm39)	K305R	probably benign	Het
Pak1	A	T	7: 97,503,686 (GRCm39)	D7V	probably benign	Het
Pax3	A	T	1: 78,173,501 (GRCm39)		probably null	Het
Plekhg1	G	A	10: 3,908,048 (GRCm39)	M988I	probably benign	Het
Prickle1	A	G	15: 93,401,518 (GRCm39)	F322S	probably damaging	Het
Prl8a2	A	G	13: 27,532,896 (GRCm39)	E36G	possibly damaging	Het
Prss45	A	G	9: 110,668,160 (GRCm39)	I118V	possibly damaging	Het
Psd4	T	G	2: 24,291,253 (GRCm39)	V597G	probably damaging	Het
Psmb10	A	G	8: 106,663,934 (GRCm39)	S108P	probably benign	Het
Pttg1ip2	T	C	5: 5,505,912 (GRCm39)	Y123C	probably benign	Het
Shank3	A	T	15: 89,405,413 (GRCm39)	K455*	probably null	Het
Spag17	T	A	3: 99,934,935 (GRCm39)	W714R	probably benign	Het
Synrg	A	G	11: 83,900,050 (GRCm39)	E674G	probably damaging	Het
Terb1	T	C	8: 105,225,227 (GRCm39)	T14A	probably damaging	Het
Tmub2	T	A	11: 102,178,581 (GRCm39)	D161E	probably benign	Het
Ttc23l	CT	CTTGGATT	15: 10,537,648 (GRCm39)		probably benign	Het
Ttc23l	G	A	15: 10,537,652 (GRCm39)	S206L	probably benign	Het
Tyr	T	A	7: 87,078,397 (GRCm39)	I488F	probably benign	Het
Uba6	A	G	5: 86,280,475 (GRCm39)		probably null	Het
Unc13c	T	C	9: 73,838,829 (GRCm39)	Y674C	probably damaging	Het
Vmn2r105	T	A	17: 20,448,097 (GRCm39)	R242S	probably benign	Het
Vmn2r12	A	G	5: 109,234,398 (GRCm39)	Y605H	probably benign	Het
Wnk1	A	G	6: 119,913,328 (GRCm39)		probably null	Het
Zfhx4	C	A	3: 5,455,465 (GRCm39)	A1153E	probably benign	Het
Zfp13	A	C	17: 23,795,186 (GRCm39)	Y462D	probably damaging	Het
Zfp644	A	G	5: 106,785,110 (GRCm39)	M479T	possibly damaging	Het

Other mutations in Tep1

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00482:Tep1	APN	14	51,080,641 (GRCm39)	missense	probably damaging	1.00
IGL00490:Tep1	APN	14	51,070,930 (GRCm39)	missense	probably damaging	0.97
IGL01114:Tep1	APN	14	51,088,096 (GRCm39)	missense	probably damaging	0.98
IGL01294:Tep1	APN	14	51,067,114 (GRCm39)	splice site	probably benign
IGL01902:Tep1	APN	14	51,103,548 (GRCm39)	splice site	probably benign
IGL01910:Tep1	APN	14	51,081,569 (GRCm39)	missense	probably benign	0.06
IGL01925:Tep1	APN	14	51,061,955 (GRCm39)	unclassified	probably benign
IGL01965:Tep1	APN	14	51,100,952 (GRCm39)	splice site	probably benign
IGL02071:Tep1	APN	14	51,071,506 (GRCm39)	missense	possibly damaging	0.93
IGL02124:Tep1	APN	14	51,091,581 (GRCm39)	unclassified	probably benign
IGL02189:Tep1	APN	14	51,064,283 (GRCm39)	missense	probably benign
IGL02252:Tep1	APN	14	51,067,712 (GRCm39)	missense	possibly damaging	0.93
IGL02299:Tep1	APN	14	51,078,128 (GRCm39)	missense	probably damaging	0.99
IGL02343:Tep1	APN	14	51,066,704 (GRCm39)	missense	probably damaging	0.99
IGL02423:Tep1	APN	14	51,082,077 (GRCm39)	missense	possibly damaging	0.53
IGL02537:Tep1	APN	14	51,073,570 (GRCm39)	missense	probably damaging	0.96
IGL02601:Tep1	APN	14	51,070,935 (GRCm39)	nonsense	probably null
IGL02941:Tep1	APN	14	51,103,494 (GRCm39)	missense	probably damaging	0.98
IGL02990:Tep1	APN	14	51,105,703 (GRCm39)	missense	possibly damaging	0.86
IGL03144:Tep1	APN	14	51,081,474 (GRCm39)	splice site	probably benign
IGL03209:Tep1	APN	14	51,078,160 (GRCm39)	splice site	probably benign
R0240_Tep1_347	UTSW	14	51,100,486 (GRCm39)	splice site	probably benign
R0972_Tep1_893	UTSW	14	51,061,753 (GRCm39)	unclassified	probably benign
R1686_Tep1_375	UTSW	14	51,074,245 (GRCm39)	missense	probably benign	0.12
R7232_Tep1_671	UTSW	14	51,081,789 (GRCm39)	missense	unknown
R8009_Tep1_822	UTSW	14	51,061,687 (GRCm39)	missense	possibly damaging	0.93
PIT4305001:Tep1	UTSW	14	51,066,684 (GRCm39)	missense	possibly damaging	0.90
PIT4362001:Tep1	UTSW	14	51,103,510 (GRCm39)	missense	probably benign	0.23
R0058:Tep1	UTSW	14	51,071,522 (GRCm39)	missense	possibly damaging	0.85
R0060:Tep1	UTSW	14	51,103,486 (GRCm39)	missense	probably damaging	1.00
R0109:Tep1	UTSW	14	51,089,373 (GRCm39)	splice site	probably null
R0123:Tep1	UTSW	14	51,067,150 (GRCm39)	missense	possibly damaging	0.84
R0134:Tep1	UTSW	14	51,067,150 (GRCm39)	missense	possibly damaging	0.84
R0148:Tep1	UTSW	14	51,062,246 (GRCm39)	missense	possibly damaging	0.70
R0240:Tep1	UTSW	14	51,100,486 (GRCm39)	splice site	probably benign
R0243:Tep1	UTSW	14	51,084,444 (GRCm39)	missense	probably damaging	1.00
R0373:Tep1	UTSW	14	51,074,225 (GRCm39)	missense	possibly damaging	0.85
R0432:Tep1	UTSW	14	51,104,280 (GRCm39)	small deletion	probably benign
R0464:Tep1	UTSW	14	51,085,141 (GRCm39)	missense	probably benign	0.00
R0566:Tep1	UTSW	14	51,082,871 (GRCm39)	critical splice donor site	probably null
R0691:Tep1	UTSW	14	51,104,301 (GRCm39)	nonsense	probably null
R0787:Tep1	UTSW	14	51,066,687 (GRCm39)	missense	possibly damaging	0.85
R0972:Tep1	UTSW	14	51,061,753 (GRCm39)	unclassified	probably benign
R1263:Tep1	UTSW	14	51,082,970 (GRCm39)	missense	possibly damaging	0.84
R1300:Tep1	UTSW	14	51,064,512 (GRCm39)	critical splice donor site	probably null
R1327:Tep1	UTSW	14	51,090,556 (GRCm39)	missense	probably benign	0.18
R1556:Tep1	UTSW	14	51,090,499 (GRCm39)	missense	probably benign	0.06
R1584:Tep1	UTSW	14	51,103,494 (GRCm39)	missense	probably damaging	0.98
R1607:Tep1	UTSW	14	51,062,020 (GRCm39)	missense	probably null	0.99
R1686:Tep1	UTSW	14	51,074,245 (GRCm39)	missense	probably benign	0.12
R1715:Tep1	UTSW	14	51,092,024 (GRCm39)	missense	possibly damaging	0.92
R1778:Tep1	UTSW	14	51,067,079 (GRCm39)	intron	probably benign
R1993:Tep1	UTSW	14	51,061,641 (GRCm39)	missense	possibly damaging	0.93
R2071:Tep1	UTSW	14	51,091,739 (GRCm39)	missense	probably benign	0.23
R2104:Tep1	UTSW	14	51,088,037 (GRCm39)	splice site	probably benign
R2118:Tep1	UTSW	14	51,093,029 (GRCm39)	splice site	probably null
R2119:Tep1	UTSW	14	51,076,443 (GRCm39)	missense	probably benign	0.13
R2208:Tep1	UTSW	14	51,104,321 (GRCm39)	missense	probably benign	0.01
R2241:Tep1	UTSW	14	51,091,667 (GRCm39)	missense	probably benign	0.01
R2243:Tep1	UTSW	14	51,091,667 (GRCm39)	missense	probably benign	0.01
R2311:Tep1	UTSW	14	51,071,024 (GRCm39)	missense	possibly damaging	0.95
R2874:Tep1	UTSW	14	51,088,107 (GRCm39)	missense	possibly damaging	0.71
R3084:Tep1	UTSW	14	51,064,511 (GRCm39)	critical splice donor site	probably null
R3086:Tep1	UTSW	14	51,064,511 (GRCm39)	critical splice donor site	probably null
R3621:Tep1	UTSW	14	51,066,477 (GRCm39)	missense	probably damaging	0.99
R3815:Tep1	UTSW	14	51,105,772 (GRCm39)	missense	possibly damaging	0.71
R4124:Tep1	UTSW	14	51,081,191 (GRCm39)	missense	possibly damaging	0.93
R4125:Tep1	UTSW	14	51,081,191 (GRCm39)	missense	possibly damaging	0.93
R4127:Tep1	UTSW	14	51,081,191 (GRCm39)	missense	possibly damaging	0.93
R4134:Tep1	UTSW	14	51,082,317 (GRCm39)	missense	probably benign
R4152:Tep1	UTSW	14	51,075,051 (GRCm39)	missense	possibly damaging	0.72
R4153:Tep1	UTSW	14	51,075,051 (GRCm39)	missense	possibly damaging	0.72
R4191:Tep1	UTSW	14	51,074,263 (GRCm39)	missense	probably damaging	0.96
R4248:Tep1	UTSW	14	51,100,351 (GRCm39)	missense	possibly damaging	0.93
R4293:Tep1	UTSW	14	51,084,318 (GRCm39)	missense	probably benign
R4569:Tep1	UTSW	14	51,062,197 (GRCm39)	missense	probably benign	0.01
R4704:Tep1	UTSW	14	51,074,530 (GRCm39)	missense	probably benign	0.06
R4815:Tep1	UTSW	14	51,078,759 (GRCm39)	missense	probably damaging	0.99
R4978:Tep1	UTSW	14	51,082,891 (GRCm39)	missense	possibly damaging	0.93
R4989:Tep1	UTSW	14	51,076,457 (GRCm39)	missense	probably benign
R5022:Tep1	UTSW	14	51,066,456 (GRCm39)	missense	probably benign	0.27
R5057:Tep1	UTSW	14	51,066,456 (GRCm39)	missense	probably benign	0.27
R5063:Tep1	UTSW	14	51,088,084 (GRCm39)	missense	possibly damaging	0.86
R5118:Tep1	UTSW	14	51,093,044 (GRCm39)	splice site	probably null
R5128:Tep1	UTSW	14	51,081,736 (GRCm39)	makesense	probably null
R5149:Tep1	UTSW	14	51,074,855 (GRCm39)	nonsense	probably null
R5171:Tep1	UTSW	14	51,062,259 (GRCm39)	missense	probably benign	0.01
R5201:Tep1	UTSW	14	51,105,567 (GRCm39)	missense	probably benign	0.01
R5260:Tep1	UTSW	14	51,076,088 (GRCm39)	missense	probably benign
R5339:Tep1	UTSW	14	51,082,031 (GRCm39)	missense	probably damaging	0.99
R5384:Tep1	UTSW	14	51,105,774 (GRCm39)	missense	probably damaging	0.98
R5385:Tep1	UTSW	14	51,105,774 (GRCm39)	missense	probably damaging	0.98
R5386:Tep1	UTSW	14	51,105,774 (GRCm39)	missense	probably damaging	0.98
R5594:Tep1	UTSW	14	51,067,339 (GRCm39)	missense	possibly damaging	0.86
R5639:Tep1	UTSW	14	51,091,062 (GRCm39)	missense	possibly damaging	0.85
R5749:Tep1	UTSW	14	51,081,529 (GRCm39)	missense	possibly damaging	0.59
R5756:Tep1	UTSW	14	51,074,836 (GRCm39)	critical splice donor site	probably null
R6013:Tep1	UTSW	14	51,098,505 (GRCm39)	missense	probably damaging	0.97
R6014:Tep1	UTSW	14	51,084,457 (GRCm39)	missense	probably benign	0.12
R6248:Tep1	UTSW	14	51,067,715 (GRCm39)	missense	probably damaging	0.98
R6264:Tep1	UTSW	14	51,082,970 (GRCm39)	missense	probably damaging	0.99
R6363:Tep1	UTSW	14	51,062,005 (GRCm39)	missense	probably benign	0.04
R6381:Tep1	UTSW	14	51,082,888 (GRCm39)	missense	probably damaging	0.99
R6462:Tep1	UTSW	14	51,081,836 (GRCm39)	missense	probably benign
R6942:Tep1	UTSW	14	51,074,194 (GRCm39)	missense	possibly damaging	0.85
R6951:Tep1	UTSW	14	51,071,370 (GRCm39)	critical splice donor site	probably null
R6979:Tep1	UTSW	14	51,076,094 (GRCm39)	missense	possibly damaging	0.93
R6999:Tep1	UTSW	14	51,088,162 (GRCm39)	missense	possibly damaging	0.86
R7099:Tep1	UTSW	14	51,081,944 (GRCm39)	splice site	probably null
R7208:Tep1	UTSW	14	51,062,013 (GRCm39)	critical splice acceptor site	probably null
R7232:Tep1	UTSW	14	51,081,789 (GRCm39)	missense	unknown
R7249:Tep1	UTSW	14	51,061,732 (GRCm39)	missense	possibly damaging	0.86
R7325:Tep1	UTSW	14	51,103,495 (GRCm39)	missense	probably damaging	0.99
R7409:Tep1	UTSW	14	51,104,312 (GRCm39)	missense	possibly damaging	0.67
R7499:Tep1	UTSW	14	51,091,047 (GRCm39)	missense	probably damaging	0.99
R7542:Tep1	UTSW	14	51,099,948 (GRCm39)	nonsense	probably null
R7806:Tep1	UTSW	14	51,074,266 (GRCm39)	missense	possibly damaging	0.85
R7825:Tep1	UTSW	14	51,081,344 (GRCm39)	critical splice acceptor site	probably null
R7901:Tep1	UTSW	14	51,064,308 (GRCm39)	missense	possibly damaging	0.88
R7961:Tep1	UTSW	14	51,061,687 (GRCm39)	missense	possibly damaging	0.93
R7993:Tep1	UTSW	14	51,067,710 (GRCm39)	missense	probably benign	0.41
R8009:Tep1	UTSW	14	51,061,687 (GRCm39)	missense	possibly damaging	0.93
R8085:Tep1	UTSW	14	51,066,753 (GRCm39)	missense	probably benign	0.11
R8299:Tep1	UTSW	14	51,105,502 (GRCm39)	missense	probably benign	0.06
R8330:Tep1	UTSW	14	51,085,162 (GRCm39)	missense	possibly damaging	0.86
R8396:Tep1	UTSW	14	51,074,529 (GRCm39)	missense	probably benign	0.23
R8475:Tep1	UTSW	14	51,078,712 (GRCm39)	missense	probably damaging	1.00
R8695:Tep1	UTSW	14	51,082,894 (GRCm39)	missense	possibly damaging	0.85
R8726:Tep1	UTSW	14	51,085,080 (GRCm39)	missense	probably damaging	0.98
R8812:Tep1	UTSW	14	51,074,589 (GRCm39)	missense	probably damaging	0.98
R9152:Tep1	UTSW	14	51,104,162 (GRCm39)	missense	probably benign	0.14
R9269:Tep1	UTSW	14	51,081,766 (GRCm39)	missense	probably damaging	0.98
R9299:Tep1	UTSW	14	51,081,988 (GRCm39)	splice site	probably benign
R9365:Tep1	UTSW	14	51,064,597 (GRCm39)	missense	probably damaging	1.00
R9398:Tep1	UTSW	14	51,066,429 (GRCm39)	missense	possibly damaging	0.85
R9408:Tep1	UTSW	14	51,074,637 (GRCm39)	missense	possibly damaging	0.85
R9445:Tep1	UTSW	14	51,082,967 (GRCm39)	missense	possibly damaging	0.95
R9487:Tep1	UTSW	14	51,066,687 (GRCm39)	missense	possibly damaging	0.93
R9555:Tep1	UTSW	14	51,105,888 (GRCm39)	missense	possibly damaging	0.52
R9597:Tep1	UTSW	14	51,100,465 (GRCm39)	missense	probably damaging	0.99
R9715:Tep1	UTSW	14	51,081,759 (GRCm39)	missense
R9732:Tep1	UTSW	14	51,088,162 (GRCm39)	missense	probably benign	0.33
R9777:Tep1	UTSW	14	51,076,443 (GRCm39)	nonsense	probably null
RF007:Tep1	UTSW	14	51,098,402 (GRCm39)	missense	possibly damaging	0.92
X0024:Tep1	UTSW	14	51,064,576 (GRCm39)	missense	possibly damaging	0.86
X0060:Tep1	UTSW	14	51,074,221 (GRCm39)	missense	probably benign	0.25
Z1177:Tep1	UTSW	14	51,085,222 (GRCm39)	missense	probably damaging	0.99

Predicted Primers

PCR Primer
(F):5'- GACCATTCAGGAATCTAGGACCAG -3'
(R):5'- ATGACTGACTCTTGCCCAGG -3'

Sequencing Primer
(F):5'- TCTAGGACCAGAGAGGCTGTG -3'
(R):5'- GCCCGTTCTGGTGACTCAC -3'

Posted On

2014-11-12