Mutagenetix > Incidental Mutation

Incidental Mutation 'R0309:Dnah7a'

25015

Institutional Source

Beutler Lab

Gene Symbol

Dnah7a

Ensembl Gene

ENSMUSG00000096141

Gene Name

dynein, axonemal, heavy chain 7A

Synonyms

Dnahc7, LOC381341, Dnahc7a

MMRRC Submission

038519-MU

Accession Numbers

Essential gene?

Probably non essential (E-score: 0.147) question?

Stock #

R0309 (G1)

Quality Score

225

Status

Validated

Chromosome

Chromosomal Location

53436165-53745943 bp(-) (GRCm39)

Type of Mutation

missense

DNA Base Change (assembly)

C to G at 53444849 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Aspartic acid to Histidine at position 3952 (D3952H)

Ref Sequence

ENSEMBL: ENSMUSP00000092571 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000094964]

AlphaFold

no structure available at present

Predicted Effect

probably damaging
Transcript: ENSMUST00000094964
AA Change: D3952H

PolyPhen 2 Score 0.974 (Sensitivity: 0.76; Specificity: 0.96)

SMART Domains

Protein: ENSMUSP00000092571
Gene: ENSMUSG00000096141
AA Change: D3952H

Domain	Start	End	E-Value	Type
low complexity region	2	15	N/A	INTRINSIC
coiled coil region	504	537	N/A	INTRINSIC
Pfam:DHC_N2	756	1165	3.1e-149	PFAM
AAA	1320	1459	2.46e-1	SMART
Blast:AAA	1601	1879	1e-87	BLAST
AAA	1968	2116	5.39e-2	SMART
Pfam:AAA_8	2303	2574	6.9e-75	PFAM
Pfam:MT	2586	2936	2.1e-55	PFAM
Pfam:AAA_9	2957	3182	1.3e-98	PFAM
Pfam:Dynein_heavy	3318	4020	2.3e-287	PFAM

Meta Mutation Damage Score

0.3176

Coding Region Coverage

1x: 98.7%
3x: 97.6%
10x: 94.3%
20x: 86.4%

Validation Efficiency

98% (125/127)

Allele List at MGI

Other mutations in this stock

Total: 126 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
4930402F06Rik	T	C	2: 35,266,271 (GRCm39)	D133G	possibly damaging	Het
Abcb4	A	C	5: 8,989,835 (GRCm39)	D796A	probably damaging	Het
Actg2	A	T	6: 83,496,896 (GRCm39)	V147E	probably damaging	Het
Adamts13	A	C	2: 26,877,001 (GRCm39)	T534P	probably damaging	Het
Ago1	T	C	4: 126,336,959 (GRCm39)	T249A	probably benign	Het
Ahnak	T	A	19: 8,979,859 (GRCm39)	I381N	probably damaging	Het
Akap9	A	G	5: 4,119,038 (GRCm39)	D3515G	probably benign	Het
Angptl3	T	C	4: 98,922,706 (GRCm39)	V249A	probably benign	Het
Ank	A	G	15: 27,567,658 (GRCm39)	T294A	possibly damaging	Het
Ank1	A	T	8: 23,594,825 (GRCm39)	H204L	probably damaging	Het
Apbb2	A	G	5: 66,468,331 (GRCm39)		probably benign	Het
Arhgap28	A	T	17: 68,208,424 (GRCm39)	S15T	probably benign	Het
Aspm	T	C	1: 139,410,249 (GRCm39)		probably benign	Het
Atp1a4	T	C	1: 172,062,554 (GRCm39)	E651G	probably damaging	Het
B3gnt2	A	T	11: 22,786,860 (GRCm39)	F109L	probably damaging	Het
Bpifb4	T	C	2: 153,801,603 (GRCm39)	F575L	probably damaging	Het
Calhm4	A	G	10: 33,920,043 (GRCm39)	W75R	probably damaging	Het
Calr	C	A	8: 85,569,660 (GRCm39)	K322N	probably benign	Het
Ccdc188	T	C	16: 18,037,169 (GRCm39)	S247P	possibly damaging	Het
Cdr1	T	A	X: 60,228,908 (GRCm39)	D86V	unknown	Het
Cep97	C	T	16: 55,745,421 (GRCm39)	V48I	probably damaging	Het
Chaf1b	T	A	16: 93,681,399 (GRCm39)	C6S	probably damaging	Het
Chd3	C	T	11: 69,247,844 (GRCm39)	D920N	probably damaging	Het
Clk1	T	C	1: 58,452,192 (GRCm39)		probably benign	Het
Cntnap3	T	A	13: 64,905,250 (GRCm39)		probably benign	Het
Col12a1	T	A	9: 79,507,293 (GRCm39)		probably null	Het
Col17a1	G	T	19: 47,659,801 (GRCm39)		probably benign	Het
Coq7	T	A	7: 118,128,940 (GRCm39)	I32F	possibly damaging	Het
Cox6a2	A	T	7: 127,805,107 (GRCm39)	F59I	probably damaging	Het
Cpq	A	G	15: 33,594,297 (GRCm39)	D436G	probably damaging	Het
Ctso	G	A	3: 81,852,168 (GRCm39)		probably null	Het
Cxadr	A	T	16: 78,131,836 (GRCm39)	H274L	probably benign	Het
Cyp2c40	A	T	19: 39,766,495 (GRCm39)	C367S	possibly damaging	Het
Cyp2c70	T	G	19: 40,149,115 (GRCm39)	M344L	possibly damaging	Het
Defa35	G	A	8: 21,555,871 (GRCm39)	V77I	probably benign	Het
Dhx57	A	G	17: 80,582,310 (GRCm39)	Y432H	probably damaging	Het
Dhx9	A	T	1: 153,341,441 (GRCm39)	D601E	probably benign	Het
Dnah9	C	A	11: 65,917,798 (GRCm39)		probably benign	Het
Dstyk	C	A	1: 132,384,602 (GRCm39)		probably benign	Het
Efcab2	T	A	1: 178,303,469 (GRCm39)		probably benign	Het
Ehbp1l1	T	C	19: 5,770,598 (GRCm39)	E287G	possibly damaging	Het
Epgn	A	G	5: 91,180,073 (GRCm39)	T87A	probably benign	Het
Erc2	A	C	14: 27,863,182 (GRCm39)	E803A	probably damaging	Het
Fer	A	G	17: 64,446,011 (GRCm39)	*454W	probably null	Het
Glyr1	T	C	16: 4,849,836 (GRCm39)	D179G	probably damaging	Het
Gm12830	T	A	4: 114,702,173 (GRCm39)		probably benign	Het
Gm9922	C	A	14: 101,967,129 (GRCm39)		probably benign	Het
Gsta3	C	T	1: 21,335,118 (GRCm39)	P200S	possibly damaging	Het
Hmgxb3	G	A	18: 61,288,200 (GRCm39)		probably benign	Het
Hsh2d	G	A	8: 72,954,304 (GRCm39)	D229N	probably benign	Het
Il16	T	C	7: 83,371,762 (GRCm39)	K15E	probably damaging	Het
Kcnip2	T	A	19: 45,782,514 (GRCm39)		probably benign	Het
Kdm4c	T	C	4: 74,263,804 (GRCm39)	V696A	probably benign	Het
Kdr	A	G	5: 76,107,587 (GRCm39)		probably benign	Het
Klhl33	T	G	14: 51,128,868 (GRCm39)	H787P	probably damaging	Het
Klk14	A	T	7: 43,343,769 (GRCm39)	T159S	probably benign	Het
Lancl2	A	G	6: 57,680,117 (GRCm39)	N16D	probably damaging	Het
Lemd3	T	C	10: 120,773,015 (GRCm39)	N583S	possibly damaging	Het
Map3k4	TGCTGGCTTCAGGGCCACAGTCCGCTG	TGCTG	17: 12,489,902 (GRCm39)		probably null	Het
Mpl	T	G	4: 118,303,235 (GRCm39)		probably benign	Het
Myh7b	T	C	2: 155,472,592 (GRCm39)		probably benign	Het
Mylk	A	C	16: 34,732,667 (GRCm39)		probably benign	Het
Myof	A	T	19: 37,969,714 (GRCm39)	M316K	probably benign	Het
Nfib	T	A	4: 82,214,974 (GRCm39)	N543I	probably damaging	Het
Nfix	A	G	8: 85,448,403 (GRCm39)	S375P	probably damaging	Het
Nkrf	T	C	X: 36,153,769 (GRCm39)	Q171R	probably damaging	Het
Nmnat2	T	A	1: 152,952,747 (GRCm39)		probably benign	Het
Npffr2	G	A	5: 89,731,206 (GRCm39)	E379K	probably benign	Het
Npr2	T	C	4: 43,640,904 (GRCm39)		probably benign	Het
Nup98	A	C	7: 101,801,635 (GRCm39)	D212E	probably null	Het
Nwd2	T	C	5: 63,964,561 (GRCm39)	Y1382H	probably damaging	Het
Ocstamp	T	C	2: 165,237,912 (GRCm39)	R451G	possibly damaging	Het
Or52s1	T	A	7: 102,861,928 (GRCm39)	I287K	probably damaging	Het
Or6c6c	A	G	10: 129,541,008 (GRCm39)	D87G	probably benign	Het
Pabpc1	C	T	15: 36,597,737 (GRCm39)	A551T	possibly damaging	Het
Pard3	A	T	8: 128,103,378 (GRCm39)		probably benign	Het
Pcdhb12	G	T	18: 37,569,174 (GRCm39)	V107L	probably benign	Het
Pik3cd	A	T	4: 149,747,677 (GRCm39)	V22D	probably damaging	Het
Pkd1l2	A	G	8: 117,724,315 (GRCm39)	V2396A	probably damaging	Het
Pnpla7	T	C	2: 24,877,207 (GRCm39)	I167T	probably damaging	Het
Pphln1	A	T	15: 93,339,588 (GRCm39)	H114L	possibly damaging	Het
Ppm1h	A	G	10: 122,756,687 (GRCm39)	N444S	probably damaging	Het
Prdm9	G	A	17: 15,777,646 (GRCm39)	T146I	probably damaging	Het
Prrc2a	A	G	17: 35,369,891 (GRCm39)		probably benign	Het
Prrx1	T	C	1: 163,140,128 (GRCm39)	D26G	possibly damaging	Het
Ptpn5	T	C	7: 46,729,042 (GRCm39)	E495G	probably damaging	Het
Rab23	A	C	1: 33,773,942 (GRCm39)		probably null	Het
Ralgps1	C	T	2: 33,047,935 (GRCm39)	M348I	probably benign	Het
Ranbp2	A	G	10: 58,315,690 (GRCm39)	T2137A	probably benign	Het
Rapgef4	G	T	2: 72,056,374 (GRCm39)	G654V	probably benign	Het
Rc3h2	A	T	2: 37,269,020 (GRCm39)		probably benign	Het
Reg2	G	A	6: 78,383,169 (GRCm39)	A39T	possibly damaging	Het
Sema4d	C	A	13: 51,879,347 (GRCm39)	V7F	probably benign	Het
Sgip1	T	C	4: 102,772,354 (GRCm39)		probably benign	Het
Sgpl1	C	T	10: 60,949,216 (GRCm39)		probably null	Het
Shisa9	G	A	16: 11,814,987 (GRCm39)	V212M	probably damaging	Het
Shq1	G	A	6: 100,550,588 (GRCm39)	P450L	probably benign	Het
Sin3a	A	G	9: 57,018,196 (GRCm39)	T872A	probably benign	Het
Sipa1l3	C	T	7: 29,047,775 (GRCm39)	R1371Q	probably benign	Het
Skint8	T	C	4: 111,796,064 (GRCm39)	V246A	probably benign	Het
Slc22a20	A	T	19: 6,022,985 (GRCm39)	V386D	probably damaging	Het
Slc28a2b	A	T	2: 122,348,034 (GRCm39)	T253S	probably benign	Het
Slc2a7	G	A	4: 150,242,528 (GRCm39)		probably benign	Het
Slc35a2	T	A	X: 7,755,901 (GRCm39)	Y48N	probably damaging	Het
Slc4a2	G	T	5: 24,639,344 (GRCm39)	S413I	probably damaging	Het
Sntg2	T	C	12: 30,276,772 (GRCm39)	T427A	probably benign	Het
Soat1	T	C	1: 156,270,023 (GRCm39)	Y132C	probably damaging	Het
Stn1	G	T	19: 47,490,112 (GRCm39)	H342N	probably benign	Het
Tarbp1	T	A	8: 127,165,667 (GRCm39)		probably benign	Het
Tas2r113	A	C	6: 132,870,341 (GRCm39)	K123T	probably damaging	Het
Tbck	C	T	3: 132,440,168 (GRCm39)	Q504*	probably null	Het
Tenm3	C	T	8: 48,794,069 (GRCm39)	C380Y	probably damaging	Het
Tent4a	A	T	13: 69,648,051 (GRCm39)	V781E	possibly damaging	Het
Triobp	A	G	15: 78,860,740 (GRCm39)	D1389G	probably damaging	Het
Trpm4	A	T	7: 44,958,130 (GRCm39)	F780I	probably damaging	Het
Tubb4a	G	T	17: 57,388,182 (GRCm39)	Y281*	probably null	Het
Txndc15	T	C	13: 55,872,395 (GRCm39)	F261S	probably damaging	Het
Ube3b	T	C	5: 114,557,530 (GRCm39)		probably benign	Het
Unc5c	G	C	3: 141,439,694 (GRCm39)	V196L	probably benign	Het
Upf3a	G	A	8: 13,845,500 (GRCm39)		probably null	Het
Vmn2r20	T	C	6: 123,363,063 (GRCm39)	K574E	probably benign	Het
Vps50	A	G	6: 3,536,853 (GRCm39)	M275V	possibly damaging	Het
Xrcc5	A	G	1: 72,346,735 (GRCm39)		probably benign	Het
Zbtb18	T	C	1: 177,276,182 (GRCm39)	L505S	probably damaging	Het
Zbtb41	T	C	1: 139,366,722 (GRCm39)	I567T	probably damaging	Het
Zfp598	T	C	17: 24,897,558 (GRCm39)		probably benign	Het

Other mutations in Dnah7a

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00479:Dnah7a	APN	1	53,458,843 (GRCm39)	missense	probably damaging	0.99
IGL00510:Dnah7a	APN	1	53,540,701 (GRCm39)	missense	probably damaging	1.00
IGL00545:Dnah7a	APN	1	53,496,905 (GRCm39)	missense	possibly damaging	0.87
IGL01320:Dnah7a	APN	1	53,473,205 (GRCm39)	missense	probably benign	0.32
IGL01322:Dnah7a	APN	1	53,473,205 (GRCm39)	missense	probably benign	0.32
IGL01357:Dnah7a	APN	1	53,701,540 (GRCm39)	missense	probably benign
IGL01417:Dnah7a	APN	1	53,623,759 (GRCm39)	missense	probably benign	0.01
IGL01508:Dnah7a	APN	1	53,666,231 (GRCm39)	missense	probably benign	0.00
IGL01511:Dnah7a	APN	1	53,458,754 (GRCm39)	missense	probably damaging	1.00
IGL01545:Dnah7a	APN	1	53,557,941 (GRCm39)	missense	probably benign
IGL01575:Dnah7a	APN	1	53,466,979 (GRCm39)	splice site	probably benign
IGL01667:Dnah7a	APN	1	53,586,451 (GRCm39)	missense	probably damaging	1.00
IGL01712:Dnah7a	APN	1	53,462,429 (GRCm39)	missense	probably benign	0.23
IGL01824:Dnah7a	APN	1	53,543,429 (GRCm39)	missense	probably benign
IGL01829:Dnah7a	APN	1	53,657,227 (GRCm39)	missense	possibly damaging	0.64
IGL01861:Dnah7a	APN	1	53,623,608 (GRCm39)	splice site	probably benign
IGL01861:Dnah7a	APN	1	53,679,508 (GRCm39)	missense	probably benign	0.01
IGL01984:Dnah7a	APN	1	53,741,174 (GRCm39)	splice site	probably null
IGL02056:Dnah7a	APN	1	53,543,501 (GRCm39)	missense	probably benign	0.17
IGL02069:Dnah7a	APN	1	53,601,053 (GRCm39)	splice site	probably benign
IGL02072:Dnah7a	APN	1	53,644,986 (GRCm39)	missense	probably damaging	1.00
IGL02110:Dnah7a	APN	1	53,450,739 (GRCm39)	missense	possibly damaging	0.52
IGL02120:Dnah7a	APN	1	53,534,876 (GRCm39)	missense	possibly damaging	0.46
IGL02128:Dnah7a	APN	1	53,476,672 (GRCm39)	missense	probably damaging	1.00
IGL02135:Dnah7a	APN	1	53,662,632 (GRCm39)	missense	probably benign	0.01
IGL02151:Dnah7a	APN	1	53,512,023 (GRCm39)	missense	probably benign	0.08
IGL02156:Dnah7a	APN	1	53,458,882 (GRCm39)	missense	probably benign	0.27
IGL02270:Dnah7a	APN	1	53,512,052 (GRCm39)	missense	possibly damaging	0.93
IGL02282:Dnah7a	APN	1	53,682,669 (GRCm39)	missense	possibly damaging	0.93
IGL02328:Dnah7a	APN	1	53,564,096 (GRCm39)	critical splice donor site	probably null
IGL02370:Dnah7a	APN	1	53,674,556 (GRCm39)	missense	probably benign	0.00
IGL02420:Dnah7a	APN	1	53,725,702 (GRCm39)	missense	probably benign
IGL02458:Dnah7a	APN	1	53,657,487 (GRCm39)	nonsense	probably null
IGL02489:Dnah7a	APN	1	53,686,481 (GRCm39)	missense	possibly damaging	0.94
IGL02554:Dnah7a	APN	1	53,657,205 (GRCm39)	missense	possibly damaging	0.93
IGL02578:Dnah7a	APN	1	53,472,074 (GRCm39)	missense	probably benign	0.00
IGL02646:Dnah7a	APN	1	53,564,194 (GRCm39)	missense	probably damaging	0.99
IGL02675:Dnah7a	APN	1	53,543,183 (GRCm39)	missense	possibly damaging	0.96
IGL02688:Dnah7a	APN	1	53,483,631 (GRCm39)	missense	possibly damaging	0.93
IGL02858:Dnah7a	APN	1	53,512,118 (GRCm39)	splice site	probably benign
IGL02874:Dnah7a	APN	1	53,644,973 (GRCm39)	missense	possibly damaging	0.70
IGL02887:Dnah7a	APN	1	53,561,519 (GRCm39)	missense	possibly damaging	0.46
IGL02894:Dnah7a	APN	1	53,616,487 (GRCm39)	missense	probably benign	0.27
IGL02926:Dnah7a	APN	1	53,535,109 (GRCm39)	missense	possibly damaging	0.64
IGL03113:Dnah7a	APN	1	53,472,163 (GRCm39)	missense	possibly damaging	0.64
IGL03156:Dnah7a	APN	1	53,644,983 (GRCm39)	missense	probably damaging	0.97
IGL03195:Dnah7a	APN	1	53,458,766 (GRCm39)	missense	probably damaging	1.00
IGL03209:Dnah7a	APN	1	53,725,773 (GRCm39)	splice site	probably benign
IGL03214:Dnah7a	APN	1	53,561,368 (GRCm39)	critical splice donor site	probably null
IGL03242:Dnah7a	APN	1	53,659,882 (GRCm39)	missense	probably benign	0.02
IGL03251:Dnah7a	APN	1	53,686,433 (GRCm39)	missense	probably benign
IGL03265:Dnah7a	APN	1	53,568,007 (GRCm39)	missense	probably benign
IGL03277:Dnah7a	APN	1	53,669,481 (GRCm39)	missense	probably benign	0.00
IGL03278:Dnah7a	APN	1	53,536,124 (GRCm39)	missense	probably benign	0.07
IGL03356:Dnah7a	APN	1	53,543,093 (GRCm39)	missense	probably benign	0.01
PIT4378001:Dnah7a	UTSW	1	53,570,362 (GRCm39)	missense	probably damaging	0.99
R0046:Dnah7a	UTSW	1	53,496,033 (GRCm39)	splice site	probably null
R0051:Dnah7a	UTSW	1	53,560,245 (GRCm39)	splice site	probably benign
R0082:Dnah7a	UTSW	1	53,557,867 (GRCm39)	missense	probably damaging	1.00
R0111:Dnah7a	UTSW	1	53,507,843 (GRCm39)	missense	probably benign	0.03
R0122:Dnah7a	UTSW	1	53,436,301 (GRCm39)	missense	probably damaging	1.00
R0245:Dnah7a	UTSW	1	53,540,685 (GRCm39)	missense	probably damaging	1.00
R0278:Dnah7a	UTSW	1	53,543,305 (GRCm39)	missense	probably benign	0.00
R0334:Dnah7a	UTSW	1	53,472,213 (GRCm39)	missense	possibly damaging	0.61
R0392:Dnah7a	UTSW	1	53,543,357 (GRCm39)	missense	probably damaging	0.97
R0452:Dnah7a	UTSW	1	53,644,978 (GRCm39)	missense	probably benign	0.00
R0511:Dnah7a	UTSW	1	53,536,285 (GRCm39)	missense	probably benign
R0576:Dnah7a	UTSW	1	53,675,246 (GRCm39)	missense	probably benign	0.12
R0592:Dnah7a	UTSW	1	53,495,771 (GRCm39)	missense	possibly damaging	0.91
R0628:Dnah7a	UTSW	1	53,536,264 (GRCm39)	missense	probably benign	0.18
R0689:Dnah7a	UTSW	1	53,659,840 (GRCm39)	nonsense	probably null
R0735:Dnah7a	UTSW	1	53,583,670 (GRCm39)	missense	possibly damaging	0.70
R0800:Dnah7a	UTSW	1	53,604,855 (GRCm39)	missense	probably damaging	1.00
R0829:Dnah7a	UTSW	1	53,543,238 (GRCm39)	missense	probably benign	0.07
R0842:Dnah7a	UTSW	1	53,540,833 (GRCm39)	missense	possibly damaging	0.88
R0879:Dnah7a	UTSW	1	53,467,019 (GRCm39)	missense	possibly damaging	0.85
R1331:Dnah7a	UTSW	1	53,507,828 (GRCm39)	missense	probably damaging	0.99
R1418:Dnah7a	UTSW	1	53,686,395 (GRCm39)	splice site	probably benign
R1421:Dnah7a	UTSW	1	53,580,032 (GRCm39)	splice site	probably benign
R1445:Dnah7a	UTSW	1	53,567,956 (GRCm39)	missense	probably benign	0.02
R1473:Dnah7a	UTSW	1	53,535,173 (GRCm39)	missense	probably benign	0.00
R1538:Dnah7a	UTSW	1	53,535,148 (GRCm39)	missense	possibly damaging	0.71
R1742:Dnah7a	UTSW	1	53,495,843 (GRCm39)	missense	probably benign	0.39
R1754:Dnah7a	UTSW	1	53,601,059 (GRCm39)	critical splice donor site	probably null
R1754:Dnah7a	UTSW	1	53,543,344 (GRCm39)	missense	probably benign	0.18
R1773:Dnah7a	UTSW	1	53,472,046 (GRCm39)	splice site	probably null
R1779:Dnah7a	UTSW	1	53,616,382 (GRCm39)	missense	probably benign
R1816:Dnah7a	UTSW	1	53,670,901 (GRCm39)	splice site	probably benign
R1817:Dnah7a	UTSW	1	53,598,307 (GRCm39)	missense	probably benign
R1818:Dnah7a	UTSW	1	53,598,307 (GRCm39)	missense	probably benign
R1819:Dnah7a	UTSW	1	53,598,307 (GRCm39)	missense	probably benign
R1873:Dnah7a	UTSW	1	53,495,691 (GRCm39)	splice site	probably benign
R1875:Dnah7a	UTSW	1	53,495,691 (GRCm39)	splice site	probably benign
R1884:Dnah7a	UTSW	1	53,580,159 (GRCm39)	missense	probably damaging	0.99
R1902:Dnah7a	UTSW	1	53,574,637 (GRCm39)	missense	probably damaging	1.00
R1903:Dnah7a	UTSW	1	53,574,637 (GRCm39)	missense	probably damaging	1.00
R1908:Dnah7a	UTSW	1	53,670,721 (GRCm39)	missense	probably benign
R1959:Dnah7a	UTSW	1	53,724,142 (GRCm39)	missense	probably benign	0.00
R1960:Dnah7a	UTSW	1	53,724,142 (GRCm39)	missense	probably benign	0.00
R1985:Dnah7a	UTSW	1	53,543,093 (GRCm39)	missense	probably benign	0.01
R1992:Dnah7a	UTSW	1	53,621,835 (GRCm39)	missense	possibly damaging	0.91
R2037:Dnah7a	UTSW	1	53,621,741 (GRCm39)	missense	probably benign	0.00
R2074:Dnah7a	UTSW	1	53,496,855 (GRCm39)	missense	probably benign	0.45
R2076:Dnah7a	UTSW	1	53,542,968 (GRCm39)	missense	probably benign	0.01
R2124:Dnah7a	UTSW	1	53,536,101 (GRCm39)	missense	possibly damaging	0.58
R2191:Dnah7a	UTSW	1	53,645,034 (GRCm39)	missense	possibly damaging	0.54
R2211:Dnah7a	UTSW	1	53,518,932 (GRCm39)	missense	probably benign	0.21
R2220:Dnah7a	UTSW	1	53,560,333 (GRCm39)	missense	probably benign
R2355:Dnah7a	UTSW	1	53,621,661 (GRCm39)	missense	probably benign	0.00
R2495:Dnah7a	UTSW	1	53,645,040 (GRCm39)	missense	probably damaging	1.00
R2901:Dnah7a	UTSW	1	53,467,031 (GRCm39)	missense	probably damaging	0.99
R2911:Dnah7a	UTSW	1	53,466,983 (GRCm39)	critical splice donor site	probably null
R2993:Dnah7a	UTSW	1	53,542,713 (GRCm39)	missense	probably damaging	1.00
R3522:Dnah7a	UTSW	1	53,657,275 (GRCm39)	missense	probably damaging	1.00
R3683:Dnah7a	UTSW	1	53,483,675 (GRCm39)	missense	probably benign
R3723:Dnah7a	UTSW	1	53,486,505 (GRCm39)	missense	probably benign	0.04
R3847:Dnah7a	UTSW	1	53,540,815 (GRCm39)	missense	probably benign	0.01
R4002:Dnah7a	UTSW	1	53,670,840 (GRCm39)	missense	probably benign
R4009:Dnah7a	UTSW	1	53,564,164 (GRCm39)	missense	probably damaging	1.00
R4063:Dnah7a	UTSW	1	53,464,376 (GRCm39)	missense	probably benign
R4193:Dnah7a	UTSW	1	53,486,493 (GRCm39)	missense	probably benign	0.00
R4236:Dnah7a	UTSW	1	53,486,524 (GRCm39)	missense	probably benign	0.00
R4399:Dnah7a	UTSW	1	53,557,886 (GRCm39)	missense	probably damaging	1.00
R4469:Dnah7a	UTSW	1	53,483,685 (GRCm39)	missense	probably benign	0.01
R4494:Dnah7a	UTSW	1	53,488,197 (GRCm39)	missense	probably benign	0.01
R4569:Dnah7a	UTSW	1	53,450,818 (GRCm39)	missense	probably benign	0.01
R4609:Dnah7a	UTSW	1	53,495,816 (GRCm39)	missense	possibly damaging	0.80
R4632:Dnah7a	UTSW	1	53,467,110 (GRCm39)	missense	probably damaging	0.97
R4703:Dnah7a	UTSW	1	53,486,476 (GRCm39)	critical splice donor site	probably null
R4781:Dnah7a	UTSW	1	53,464,367 (GRCm39)	missense	probably benign	0.28
R4854:Dnah7a	UTSW	1	53,745,888 (GRCm39)	utr 5 prime	probably benign
R4932:Dnah7a	UTSW	1	53,542,737 (GRCm39)	missense	possibly damaging	0.90
R4976:Dnah7a	UTSW	1	53,737,851 (GRCm39)	missense	probably benign
R5000:Dnah7a	UTSW	1	53,606,201 (GRCm39)	missense	probably damaging	1.00
R5023:Dnah7a	UTSW	1	53,686,407 (GRCm39)	nonsense	probably null
R5026:Dnah7a	UTSW	1	53,701,657 (GRCm39)	missense	probably damaging	0.99
R5050:Dnah7a	UTSW	1	53,536,255 (GRCm39)	missense	probably benign	0.01
R5119:Dnah7a	UTSW	1	53,737,851 (GRCm39)	missense	probably benign
R5151:Dnah7a	UTSW	1	53,659,929 (GRCm39)	missense	probably benign	0.00
R5155:Dnah7a	UTSW	1	53,682,654 (GRCm39)	missense	probably benign	0.01
R5180:Dnah7a	UTSW	1	53,462,446 (GRCm39)	missense	probably damaging	0.97
R5228:Dnah7a	UTSW	1	53,476,768 (GRCm39)	critical splice acceptor site	probably null
R5237:Dnah7a	UTSW	1	53,486,690 (GRCm39)	splice site	probably null
R5267:Dnah7a	UTSW	1	53,518,851 (GRCm39)	missense	probably damaging	1.00
R5334:Dnah7a	UTSW	1	53,542,805 (GRCm39)	missense	probably benign	0.00
R5358:Dnah7a	UTSW	1	53,586,331 (GRCm39)	missense	probably damaging	1.00
R5401:Dnah7a	UTSW	1	53,670,812 (GRCm39)	missense	probably benign	0.01
R5412:Dnah7a	UTSW	1	53,674,503 (GRCm39)	missense	probably benign
R5496:Dnah7a	UTSW	1	53,496,927 (GRCm39)	missense	probably benign
R5531:Dnah7a	UTSW	1	53,458,907 (GRCm39)	missense	possibly damaging	0.50
R5536:Dnah7a	UTSW	1	53,464,412 (GRCm39)	missense	probably benign
R5543:Dnah7a	UTSW	1	53,543,228 (GRCm39)	missense	probably damaging	1.00
R5597:Dnah7a	UTSW	1	53,573,611 (GRCm39)	missense	probably benign	0.00
R5609:Dnah7a	UTSW	1	53,621,753 (GRCm39)	missense	probably benign	0.03
R5643:Dnah7a	UTSW	1	53,444,866 (GRCm39)	missense	probably benign
R5644:Dnah7a	UTSW	1	53,580,138 (GRCm39)	missense	probably benign	0.33
R5689:Dnah7a	UTSW	1	53,444,857 (GRCm39)	missense	possibly damaging	0.87
R5715:Dnah7a	UTSW	1	53,452,937 (GRCm39)	missense	probably damaging	1.00
R5780:Dnah7a	UTSW	1	53,522,478 (GRCm39)	missense	probably benign	0.03
R5893:Dnah7a	UTSW	1	53,496,944 (GRCm39)	missense	possibly damaging	0.66
R5946:Dnah7a	UTSW	1	53,598,467 (GRCm39)	missense	probably damaging	1.00
R5995:Dnah7a	UTSW	1	53,659,829 (GRCm39)	missense	probably benign	0.00
R6102:Dnah7a	UTSW	1	53,598,299 (GRCm39)	missense	probably benign	0.00
R6108:Dnah7a	UTSW	1	53,496,004 (GRCm39)	missense	probably damaging	1.00
R6133:Dnah7a	UTSW	1	53,458,814 (GRCm39)	missense	probably benign	0.05
R6168:Dnah7a	UTSW	1	53,450,727 (GRCm39)	missense	probably damaging	1.00
R6175:Dnah7a	UTSW	1	53,472,181 (GRCm39)	missense	probably damaging	1.00
R6211:Dnah7a	UTSW	1	53,458,795 (GRCm39)	missense	probably damaging	0.99
R6282:Dnah7a	UTSW	1	53,542,760 (GRCm39)	missense	probably damaging	1.00
R6329:Dnah7a	UTSW	1	53,580,273 (GRCm39)	missense	probably damaging	1.00
R6344:Dnah7a	UTSW	1	53,436,349 (GRCm39)	missense	probably benign	0.02
R6530:Dnah7a	UTSW	1	53,542,856 (GRCm39)	missense	probably benign	0.04
R6574:Dnah7a	UTSW	1	53,495,693 (GRCm39)	critical splice donor site	probably null
R6608:Dnah7a	UTSW	1	53,564,277 (GRCm39)	missense	probably benign
R6625:Dnah7a	UTSW	1	53,604,916 (GRCm39)	missense	probably benign	0.05
R6661:Dnah7a	UTSW	1	53,662,609 (GRCm39)	missense	probably benign	0.00
R6681:Dnah7a	UTSW	1	53,560,385 (GRCm39)	critical splice acceptor site	probably null
R6747:Dnah7a	UTSW	1	53,675,221 (GRCm39)	missense	probably benign	0.01
R6774:Dnah7a	UTSW	1	53,737,810 (GRCm39)	missense	probably benign
R6823:Dnah7a	UTSW	1	53,495,863 (GRCm39)	missense	probably benign
R6900:Dnah7a	UTSW	1	53,701,510 (GRCm39)	missense	probably damaging	0.97
R6940:Dnah7a	UTSW	1	53,670,836 (GRCm39)	missense	probably benign	0.09
R6956:Dnah7a	UTSW	1	53,616,446 (GRCm39)	missense	probably benign	0.02
R6978:Dnah7a	UTSW	1	53,701,526 (GRCm39)	missense	probably null
R6988:Dnah7a	UTSW	1	53,621,784 (GRCm39)	missense	possibly damaging	0.62
R7026:Dnah7a	UTSW	1	53,543,448 (GRCm39)	missense	probably benign
R7027:Dnah7a	UTSW	1	53,670,665 (GRCm39)	missense	probably benign	0.01
R7033:Dnah7a	UTSW	1	53,518,820 (GRCm39)	missense	probably damaging	1.00
R7072:Dnah7a	UTSW	1	53,458,912 (GRCm39)	missense	probably benign	0.00
R7096:Dnah7a	UTSW	1	53,522,599 (GRCm39)	missense	possibly damaging	0.90
R7142:Dnah7a	UTSW	1	53,452,927 (GRCm39)	nonsense	probably null
R7144:Dnah7a	UTSW	1	53,737,867 (GRCm39)	splice site	probably null
R7167:Dnah7a	UTSW	1	53,542,935 (GRCm39)	missense	probably benign	0.00
R7182:Dnah7a	UTSW	1	53,659,620 (GRCm39)	splice site	probably null
R7196:Dnah7a	UTSW	1	53,724,000 (GRCm39)	missense	probably benign	0.00
R7206:Dnah7a	UTSW	1	53,737,792 (GRCm39)	nonsense	probably null
R7215:Dnah7a	UTSW	1	53,657,509 (GRCm39)	missense	probably damaging	0.99
R7224:Dnah7a	UTSW	1	53,436,420 (GRCm39)	missense	probably benign	0.00
R7264:Dnah7a	UTSW	1	53,557,973 (GRCm39)	missense	probably benign
R7282:Dnah7a	UTSW	1	53,724,059 (GRCm39)	critical splice acceptor site	probably null
R7365:Dnah7a	UTSW	1	53,536,297 (GRCm39)	missense	probably benign
R7392:Dnah7a	UTSW	1	53,540,820 (GRCm39)	missense	probably benign	0.00
R7454:Dnah7a	UTSW	1	53,557,923 (GRCm39)	missense	probably benign
R7471:Dnah7a	UTSW	1	53,458,858 (GRCm39)	missense	probably damaging	1.00
R7547:Dnah7a	UTSW	1	53,702,996 (GRCm39)	missense	probably benign	0.00
R7554:Dnah7a	UTSW	1	53,567,857 (GRCm39)	missense	possibly damaging	0.87
R7655:Dnah7a	UTSW	1	53,535,164 (GRCm39)	missense	possibly damaging	0.50
R7656:Dnah7a	UTSW	1	53,535,164 (GRCm39)	missense	possibly damaging	0.50
R7666:Dnah7a	UTSW	1	53,586,456 (GRCm39)	missense	probably benign	0.00
R7721:Dnah7a	UTSW	1	53,670,842 (GRCm39)	missense	probably benign
R7813:Dnah7a	UTSW	1	53,657,245 (GRCm39)	missense	probably benign
R7839:Dnah7a	UTSW	1	53,606,334 (GRCm39)	missense	probably benign	0.08
R7959:Dnah7a	UTSW	1	53,682,621 (GRCm39)	missense	probably benign	0.00
R7984:Dnah7a	UTSW	1	53,543,377 (GRCm39)	missense	probably benign	0.01
R7985:Dnah7a	UTSW	1	53,557,886 (GRCm39)	missense	probably damaging	1.00
R8116:Dnah7a	UTSW	1	53,543,049 (GRCm39)	missense	probably benign
R8140:Dnah7a	UTSW	1	53,540,748 (GRCm39)	missense	probably benign	0.02
R8184:Dnah7a	UTSW	1	53,666,194 (GRCm39)	missense	probably benign	0.03
R8339:Dnah7a	UTSW	1	53,724,178 (GRCm39)	missense	probably benign
R8352:Dnah7a	UTSW	1	53,466,986 (GRCm39)	missense	probably null	0.01
R8423:Dnah7a	UTSW	1	53,512,063 (GRCm39)	missense	possibly damaging	0.84
R8428:Dnah7a	UTSW	1	53,512,112 (GRCm39)	missense	probably damaging	0.98
R8432:Dnah7a	UTSW	1	53,657,195 (GRCm39)	missense	possibly damaging	0.46
R8452:Dnah7a	UTSW	1	53,466,986 (GRCm39)	missense	probably null	0.01
R8458:Dnah7a	UTSW	1	53,657,142 (GRCm39)	missense	probably benign	0.01
R8493:Dnah7a	UTSW	1	53,512,067 (GRCm39)	missense	probably damaging	1.00
R8498:Dnah7a	UTSW	1	53,657,139 (GRCm39)	missense	probably benign	0.01
R8502:Dnah7a	UTSW	1	53,679,520 (GRCm39)	missense	probably benign	0.39
R8692:Dnah7a	UTSW	1	53,472,175 (GRCm39)	missense	probably benign	0.00
R8700:Dnah7a	UTSW	1	53,535,088 (GRCm39)	missense	possibly damaging	0.62
R8709:Dnah7a	UTSW	1	53,674,476 (GRCm39)	missense	probably benign
R8856:Dnah7a	UTSW	1	53,462,422 (GRCm39)	missense	probably damaging	1.00
R8875:Dnah7a	UTSW	1	53,682,682 (GRCm39)	missense	probably benign	0.10
R8967:Dnah7a	UTSW	1	53,682,594 (GRCm39)	splice site	probably benign
R8982:Dnah7a	UTSW	1	53,570,301 (GRCm39)	missense	probably benign
R8984:Dnah7a	UTSW	1	53,674,436 (GRCm39)	nonsense	probably null
R8993:Dnah7a	UTSW	1	53,543,262 (GRCm39)	missense	probably damaging	1.00
R9008:Dnah7a	UTSW	1	53,701,501 (GRCm39)	missense	possibly damaging	0.81
R9022:Dnah7a	UTSW	1	53,512,116 (GRCm39)	critical splice acceptor site	probably null
R9028:Dnah7a	UTSW	1	53,560,297 (GRCm39)	missense	probably benign	0.00
R9077:Dnah7a	UTSW	1	53,741,218 (GRCm39)	missense	unknown
R9167:Dnah7a	UTSW	1	53,657,370 (GRCm39)	missense	probably benign	0.00
R9206:Dnah7a	UTSW	1	53,540,757 (GRCm39)	missense	probably benign	0.11
R9226:Dnah7a	UTSW	1	53,560,326 (GRCm39)	missense	possibly damaging	0.93
R9251:Dnah7a	UTSW	1	53,621,671 (GRCm39)	missense	probably damaging	1.00
R9265:Dnah7a	UTSW	1	53,674,505 (GRCm39)	missense	probably benign
R9350:Dnah7a	UTSW	1	53,436,307 (GRCm39)	missense	probably benign	0.19
R9369:Dnah7a	UTSW	1	53,564,222 (GRCm39)	missense	possibly damaging	0.72
R9369:Dnah7a	UTSW	1	53,543,421 (GRCm39)	missense	probably benign
R9372:Dnah7a	UTSW	1	53,543,474 (GRCm39)	missense	probably benign
R9376:Dnah7a	UTSW	1	53,568,058 (GRCm39)	critical splice acceptor site	probably null
R9378:Dnah7a	UTSW	1	53,621,776 (GRCm39)	missense	probably benign	0.32
R9401:Dnah7a	UTSW	1	53,568,026 (GRCm39)	missense	probably benign	0.01
R9431:Dnah7a	UTSW	1	53,450,812 (GRCm39)	missense	possibly damaging	0.90
R9529:Dnah7a	UTSW	1	53,561,495 (GRCm39)	missense	probably damaging	1.00
R9701:Dnah7a	UTSW	1	53,561,388 (GRCm39)	missense	probably benign	0.03
R9712:Dnah7a	UTSW	1	53,598,299 (GRCm39)	missense	probably benign	0.00
R9799:Dnah7a	UTSW	1	53,557,968 (GRCm39)	missense	probably benign	0.00
R9802:Dnah7a	UTSW	1	53,561,388 (GRCm39)	missense	probably benign	0.03
X0027:Dnah7a	UTSW	1	53,512,089 (GRCm39)	missense	probably damaging	1.00
Z1088:Dnah7a	UTSW	1	53,507,802 (GRCm39)	missense	probably damaging	1.00
Z1176:Dnah7a	UTSW	1	53,522,622 (GRCm39)	missense	probably damaging	1.00
Z1176:Dnah7a	UTSW	1	53,458,858 (GRCm39)	missense	probably damaging	1.00
Z1177:Dnah7a	UTSW	1	53,598,261 (GRCm39)	missense	probably benign	0.21
Z1177:Dnah7a	UTSW	1	53,450,815 (GRCm39)	missense	probably benign	0.08
Z1177:Dnah7a	UTSW	1	53,682,616 (GRCm39)	missense	possibly damaging	0.92

Predicted Primers

PCR Primer
(F):5'- GACATTGCTCCTCACCGCTCATTAA -3'
(R):5'- ATGCAGGGCTCAGTCACCTATCATT -3'

Sequencing Primer
(F):5'- gcagtccagtccagtgttc -3'
(R):5'- AGTCACCTATCATTTTTGAGTGC -3'

Posted On

2013-04-16