Incidental Mutation 'R0309:Nwd2'
| ID |
25048 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Nwd2
|
| Ensembl Gene |
ENSMUSG00000090061 |
| Gene Name |
NACHT and WD repeat domain containing 2 |
| Synonyms |
3110047P20Rik, B830017A01Rik |
| MMRRC Submission |
038519-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.120)
|
| Stock # |
R0309 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
|
| Chromosome |
5 |
| Chromosomal Location |
63806446-63967889 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to C
at 63964561 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Tyrosine to Histidine
at position 1382
(Y1382H)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000124712
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000159584]
|
| AlphaFold |
Q6P5U7 |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000159584
AA Change: Y1382H
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000124712
Gene: ENSMUSG00000090061
AA Change: Y1382H
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:DUF4062
|
42 |
145 |
1.5e-8 |
PFAM |
|
Blast:AAA
|
408 |
691 |
3e-29 |
BLAST |
|
WD40
|
939 |
995 |
1.06e2 |
SMART |
|
WD40
|
998 |
1037 |
8.96e-2 |
SMART |
|
Blast:WD40
|
1091 |
1126 |
9e-19 |
BLAST |
|
Blast:WD40
|
1129 |
1170 |
1e-17 |
BLAST |
|
Blast:WD40
|
1220 |
1260 |
3e-16 |
BLAST |
|
WD40
|
1263 |
1302 |
3.4e-2 |
SMART |
|
WD40
|
1347 |
1385 |
2.65e1 |
SMART |
|
WD40
|
1386 |
1425 |
1.58e2 |
SMART |
|
Blast:WD40
|
1466 |
1507 |
3e-19 |
BLAST |
|
Blast:WD40
|
1606 |
1644 |
4e-18 |
BLAST |
|
Blast:KR
|
1686 |
1730 |
2e-16 |
BLAST |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000162757
|
| Meta Mutation Damage Score |
0.2997 |
| Coding Region Coverage |
- 1x: 98.7%
- 3x: 97.6%
- 10x: 94.3%
- 20x: 86.4%
|
| Validation Efficiency |
98% (125/127) |
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 126 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 4930402F06Rik |
T |
C |
2: 35,266,271 (GRCm39) |
D133G |
possibly damaging |
Het |
| Abcb4 |
A |
C |
5: 8,989,835 (GRCm39) |
D796A |
probably damaging |
Het |
| Actg2 |
A |
T |
6: 83,496,896 (GRCm39) |
V147E |
probably damaging |
Het |
| Adamts13 |
A |
C |
2: 26,877,001 (GRCm39) |
T534P |
probably damaging |
Het |
| Ago1 |
T |
C |
4: 126,336,959 (GRCm39) |
T249A |
probably benign |
Het |
| Ahnak |
T |
A |
19: 8,979,859 (GRCm39) |
I381N |
probably damaging |
Het |
| Akap9 |
A |
G |
5: 4,119,038 (GRCm39) |
D3515G |
probably benign |
Het |
| Angptl3 |
T |
C |
4: 98,922,706 (GRCm39) |
V249A |
probably benign |
Het |
| Ank |
A |
G |
15: 27,567,658 (GRCm39) |
T294A |
possibly damaging |
Het |
| Ank1 |
A |
T |
8: 23,594,825 (GRCm39) |
H204L |
probably damaging |
Het |
| Apbb2 |
A |
G |
5: 66,468,331 (GRCm39) |
|
probably benign |
Het |
| Arhgap28 |
A |
T |
17: 68,208,424 (GRCm39) |
S15T |
probably benign |
Het |
| Aspm |
T |
C |
1: 139,410,249 (GRCm39) |
|
probably benign |
Het |
| Atp1a4 |
T |
C |
1: 172,062,554 (GRCm39) |
E651G |
probably damaging |
Het |
| B3gnt2 |
A |
T |
11: 22,786,860 (GRCm39) |
F109L |
probably damaging |
Het |
| Bpifb4 |
T |
C |
2: 153,801,603 (GRCm39) |
F575L |
probably damaging |
Het |
| Calhm4 |
A |
G |
10: 33,920,043 (GRCm39) |
W75R |
probably damaging |
Het |
| Calr |
C |
A |
8: 85,569,660 (GRCm39) |
K322N |
probably benign |
Het |
| Ccdc188 |
T |
C |
16: 18,037,169 (GRCm39) |
S247P |
possibly damaging |
Het |
| Cdr1 |
T |
A |
X: 60,228,908 (GRCm39) |
D86V |
unknown |
Het |
| Cep97 |
C |
T |
16: 55,745,421 (GRCm39) |
V48I |
probably damaging |
Het |
| Chaf1b |
T |
A |
16: 93,681,399 (GRCm39) |
C6S |
probably damaging |
Het |
| Chd3 |
C |
T |
11: 69,247,844 (GRCm39) |
D920N |
probably damaging |
Het |
| Clk1 |
T |
C |
1: 58,452,192 (GRCm39) |
|
probably benign |
Het |
| Cntnap3 |
T |
A |
13: 64,905,250 (GRCm39) |
|
probably benign |
Het |
| Col12a1 |
T |
A |
9: 79,507,293 (GRCm39) |
|
probably null |
Het |
| Col17a1 |
G |
T |
19: 47,659,801 (GRCm39) |
|
probably benign |
Het |
| Coq7 |
T |
A |
7: 118,128,940 (GRCm39) |
I32F |
possibly damaging |
Het |
| Cox6a2 |
A |
T |
7: 127,805,107 (GRCm39) |
F59I |
probably damaging |
Het |
| Cpq |
A |
G |
15: 33,594,297 (GRCm39) |
D436G |
probably damaging |
Het |
| Ctso |
G |
A |
3: 81,852,168 (GRCm39) |
|
probably null |
Het |
| Cxadr |
A |
T |
16: 78,131,836 (GRCm39) |
H274L |
probably benign |
Het |
| Cyp2c40 |
A |
T |
19: 39,766,495 (GRCm39) |
C367S |
possibly damaging |
Het |
| Cyp2c70 |
T |
G |
19: 40,149,115 (GRCm39) |
M344L |
possibly damaging |
Het |
| Defa35 |
G |
A |
8: 21,555,871 (GRCm39) |
V77I |
probably benign |
Het |
| Dhx57 |
A |
G |
17: 80,582,310 (GRCm39) |
Y432H |
probably damaging |
Het |
| Dhx9 |
A |
T |
1: 153,341,441 (GRCm39) |
D601E |
probably benign |
Het |
| Dnah7a |
C |
G |
1: 53,444,849 (GRCm39) |
D3952H |
probably damaging |
Het |
| Dnah9 |
C |
A |
11: 65,917,798 (GRCm39) |
|
probably benign |
Het |
| Dstyk |
C |
A |
1: 132,384,602 (GRCm39) |
|
probably benign |
Het |
| Efcab2 |
T |
A |
1: 178,303,469 (GRCm39) |
|
probably benign |
Het |
| Ehbp1l1 |
T |
C |
19: 5,770,598 (GRCm39) |
E287G |
possibly damaging |
Het |
| Epgn |
A |
G |
5: 91,180,073 (GRCm39) |
T87A |
probably benign |
Het |
| Erc2 |
A |
C |
14: 27,863,182 (GRCm39) |
E803A |
probably damaging |
Het |
| Fer |
A |
G |
17: 64,446,011 (GRCm39) |
*454W |
probably null |
Het |
| Glyr1 |
T |
C |
16: 4,849,836 (GRCm39) |
D179G |
probably damaging |
Het |
| Gm12830 |
T |
A |
4: 114,702,173 (GRCm39) |
|
probably benign |
Het |
| Gm9922 |
C |
A |
14: 101,967,129 (GRCm39) |
|
probably benign |
Het |
| Gsta3 |
C |
T |
1: 21,335,118 (GRCm39) |
P200S |
possibly damaging |
Het |
| Hmgxb3 |
G |
A |
18: 61,288,200 (GRCm39) |
|
probably benign |
Het |
| Hsh2d |
G |
A |
8: 72,954,304 (GRCm39) |
D229N |
probably benign |
Het |
| Il16 |
T |
C |
7: 83,371,762 (GRCm39) |
K15E |
probably damaging |
Het |
| Kcnip2 |
T |
A |
19: 45,782,514 (GRCm39) |
|
probably benign |
Het |
| Kdm4c |
T |
C |
4: 74,263,804 (GRCm39) |
V696A |
probably benign |
Het |
| Kdr |
A |
G |
5: 76,107,587 (GRCm39) |
|
probably benign |
Het |
| Klhl33 |
T |
G |
14: 51,128,868 (GRCm39) |
H787P |
probably damaging |
Het |
| Klk14 |
A |
T |
7: 43,343,769 (GRCm39) |
T159S |
probably benign |
Het |
| Lancl2 |
A |
G |
6: 57,680,117 (GRCm39) |
N16D |
probably damaging |
Het |
| Lemd3 |
T |
C |
10: 120,773,015 (GRCm39) |
N583S |
possibly damaging |
Het |
| Map3k4 |
TGCTGGCTTCAGGGCCACAGTCCGCTG |
TGCTG |
17: 12,489,902 (GRCm39) |
|
probably null |
Het |
| Mpl |
T |
G |
4: 118,303,235 (GRCm39) |
|
probably benign |
Het |
| Myh7b |
T |
C |
2: 155,472,592 (GRCm39) |
|
probably benign |
Het |
| Mylk |
A |
C |
16: 34,732,667 (GRCm39) |
|
probably benign |
Het |
| Myof |
A |
T |
19: 37,969,714 (GRCm39) |
M316K |
probably benign |
Het |
| Nfib |
T |
A |
4: 82,214,974 (GRCm39) |
N543I |
probably damaging |
Het |
| Nfix |
A |
G |
8: 85,448,403 (GRCm39) |
S375P |
probably damaging |
Het |
| Nkrf |
T |
C |
X: 36,153,769 (GRCm39) |
Q171R |
probably damaging |
Het |
| Nmnat2 |
T |
A |
1: 152,952,747 (GRCm39) |
|
probably benign |
Het |
| Npffr2 |
G |
A |
5: 89,731,206 (GRCm39) |
E379K |
probably benign |
Het |
| Npr2 |
T |
C |
4: 43,640,904 (GRCm39) |
|
probably benign |
Het |
| Nup98 |
A |
C |
7: 101,801,635 (GRCm39) |
D212E |
probably null |
Het |
| Ocstamp |
T |
C |
2: 165,237,912 (GRCm39) |
R451G |
possibly damaging |
Het |
| Or52s1 |
T |
A |
7: 102,861,928 (GRCm39) |
I287K |
probably damaging |
Het |
| Or6c6c |
A |
G |
10: 129,541,008 (GRCm39) |
D87G |
probably benign |
Het |
| Pabpc1 |
C |
T |
15: 36,597,737 (GRCm39) |
A551T |
possibly damaging |
Het |
| Pard3 |
A |
T |
8: 128,103,378 (GRCm39) |
|
probably benign |
Het |
| Pcdhb12 |
G |
T |
18: 37,569,174 (GRCm39) |
V107L |
probably benign |
Het |
| Pik3cd |
A |
T |
4: 149,747,677 (GRCm39) |
V22D |
probably damaging |
Het |
| Pkd1l2 |
A |
G |
8: 117,724,315 (GRCm39) |
V2396A |
probably damaging |
Het |
| Pnpla7 |
T |
C |
2: 24,877,207 (GRCm39) |
I167T |
probably damaging |
Het |
| Pphln1 |
A |
T |
15: 93,339,588 (GRCm39) |
H114L |
possibly damaging |
Het |
| Ppm1h |
A |
G |
10: 122,756,687 (GRCm39) |
N444S |
probably damaging |
Het |
| Prdm9 |
G |
A |
17: 15,777,646 (GRCm39) |
T146I |
probably damaging |
Het |
| Prrc2a |
A |
G |
17: 35,369,891 (GRCm39) |
|
probably benign |
Het |
| Prrx1 |
T |
C |
1: 163,140,128 (GRCm39) |
D26G |
possibly damaging |
Het |
| Ptpn5 |
T |
C |
7: 46,729,042 (GRCm39) |
E495G |
probably damaging |
Het |
| Rab23 |
A |
C |
1: 33,773,942 (GRCm39) |
|
probably null |
Het |
| Ralgps1 |
C |
T |
2: 33,047,935 (GRCm39) |
M348I |
probably benign |
Het |
| Ranbp2 |
A |
G |
10: 58,315,690 (GRCm39) |
T2137A |
probably benign |
Het |
| Rapgef4 |
G |
T |
2: 72,056,374 (GRCm39) |
G654V |
probably benign |
Het |
| Rc3h2 |
A |
T |
2: 37,269,020 (GRCm39) |
|
probably benign |
Het |
| Reg2 |
G |
A |
6: 78,383,169 (GRCm39) |
A39T |
possibly damaging |
Het |
| Sema4d |
C |
A |
13: 51,879,347 (GRCm39) |
V7F |
probably benign |
Het |
| Sgip1 |
T |
C |
4: 102,772,354 (GRCm39) |
|
probably benign |
Het |
| Sgpl1 |
C |
T |
10: 60,949,216 (GRCm39) |
|
probably null |
Het |
| Shisa9 |
G |
A |
16: 11,814,987 (GRCm39) |
V212M |
probably damaging |
Het |
| Shq1 |
G |
A |
6: 100,550,588 (GRCm39) |
P450L |
probably benign |
Het |
| Sin3a |
A |
G |
9: 57,018,196 (GRCm39) |
T872A |
probably benign |
Het |
| Sipa1l3 |
C |
T |
7: 29,047,775 (GRCm39) |
R1371Q |
probably benign |
Het |
| Skint8 |
T |
C |
4: 111,796,064 (GRCm39) |
V246A |
probably benign |
Het |
| Slc22a20 |
A |
T |
19: 6,022,985 (GRCm39) |
V386D |
probably damaging |
Het |
| Slc28a2b |
A |
T |
2: 122,348,034 (GRCm39) |
T253S |
probably benign |
Het |
| Slc2a7 |
G |
A |
4: 150,242,528 (GRCm39) |
|
probably benign |
Het |
| Slc35a2 |
T |
A |
X: 7,755,901 (GRCm39) |
Y48N |
probably damaging |
Het |
| Slc4a2 |
G |
T |
5: 24,639,344 (GRCm39) |
S413I |
probably damaging |
Het |
| Sntg2 |
T |
C |
12: 30,276,772 (GRCm39) |
T427A |
probably benign |
Het |
| Soat1 |
T |
C |
1: 156,270,023 (GRCm39) |
Y132C |
probably damaging |
Het |
| Stn1 |
G |
T |
19: 47,490,112 (GRCm39) |
H342N |
probably benign |
Het |
| Tarbp1 |
T |
A |
8: 127,165,667 (GRCm39) |
|
probably benign |
Het |
| Tas2r113 |
A |
C |
6: 132,870,341 (GRCm39) |
K123T |
probably damaging |
Het |
| Tbck |
C |
T |
3: 132,440,168 (GRCm39) |
Q504* |
probably null |
Het |
| Tenm3 |
C |
T |
8: 48,794,069 (GRCm39) |
C380Y |
probably damaging |
Het |
| Tent4a |
A |
T |
13: 69,648,051 (GRCm39) |
V781E |
possibly damaging |
Het |
| Triobp |
A |
G |
15: 78,860,740 (GRCm39) |
D1389G |
probably damaging |
Het |
| Trpm4 |
A |
T |
7: 44,958,130 (GRCm39) |
F780I |
probably damaging |
Het |
| Tubb4a |
G |
T |
17: 57,388,182 (GRCm39) |
Y281* |
probably null |
Het |
| Txndc15 |
T |
C |
13: 55,872,395 (GRCm39) |
F261S |
probably damaging |
Het |
| Ube3b |
T |
C |
5: 114,557,530 (GRCm39) |
|
probably benign |
Het |
| Unc5c |
G |
C |
3: 141,439,694 (GRCm39) |
V196L |
probably benign |
Het |
| Upf3a |
G |
A |
8: 13,845,500 (GRCm39) |
|
probably null |
Het |
| Vmn2r20 |
T |
C |
6: 123,363,063 (GRCm39) |
K574E |
probably benign |
Het |
| Vps50 |
A |
G |
6: 3,536,853 (GRCm39) |
M275V |
possibly damaging |
Het |
| Xrcc5 |
A |
G |
1: 72,346,735 (GRCm39) |
|
probably benign |
Het |
| Zbtb18 |
T |
C |
1: 177,276,182 (GRCm39) |
L505S |
probably damaging |
Het |
| Zbtb41 |
T |
C |
1: 139,366,722 (GRCm39) |
I567T |
probably damaging |
Het |
| Zfp598 |
T |
C |
17: 24,897,558 (GRCm39) |
|
probably benign |
Het |
|
| Other mutations in Nwd2 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00325:Nwd2
|
APN |
5 |
63,962,818 (GRCm39) |
missense |
probably benign |
|
|
IGL01111:Nwd2
|
APN |
5 |
63,964,643 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01152:Nwd2
|
APN |
5 |
63,963,872 (GRCm39) |
missense |
possibly damaging |
0.74 |
|
IGL01307:Nwd2
|
APN |
5 |
63,965,626 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
IGL01449:Nwd2
|
APN |
5 |
63,962,937 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01624:Nwd2
|
APN |
5 |
63,964,153 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01997:Nwd2
|
APN |
5 |
63,961,938 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL02007:Nwd2
|
APN |
5 |
63,962,042 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
IGL02143:Nwd2
|
APN |
5 |
63,948,996 (GRCm39) |
splice site |
probably null |
|
|
IGL02184:Nwd2
|
APN |
5 |
63,963,020 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02379:Nwd2
|
APN |
5 |
63,962,644 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02489:Nwd2
|
APN |
5 |
63,962,570 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02580:Nwd2
|
APN |
5 |
63,965,512 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL02682:Nwd2
|
APN |
5 |
63,962,021 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02682:Nwd2
|
APN |
5 |
63,962,020 (GRCm39) |
missense |
probably benign |
0.03 |
|
IGL02891:Nwd2
|
APN |
5 |
63,882,570 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
IGL03135:Nwd2
|
APN |
5 |
63,963,338 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03149:Nwd2
|
APN |
5 |
63,963,338 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0113:Nwd2
|
UTSW |
5 |
63,965,241 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0172:Nwd2
|
UTSW |
5 |
63,963,712 (GRCm39) |
missense |
probably benign |
0.44 |
|
R0196:Nwd2
|
UTSW |
5 |
63,963,694 (GRCm39) |
missense |
probably benign |
0.37 |
|
R0239:Nwd2
|
UTSW |
5 |
63,957,467 (GRCm39) |
missense |
probably benign |
0.01 |
|
R0239:Nwd2
|
UTSW |
5 |
63,957,467 (GRCm39) |
missense |
probably benign |
0.01 |
|
R0311:Nwd2
|
UTSW |
5 |
63,962,341 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0335:Nwd2
|
UTSW |
5 |
63,962,116 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0384:Nwd2
|
UTSW |
5 |
63,963,025 (GRCm39) |
missense |
probably benign |
0.11 |
|
R0496:Nwd2
|
UTSW |
5 |
63,963,686 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0497:Nwd2
|
UTSW |
5 |
63,963,686 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0498:Nwd2
|
UTSW |
5 |
63,963,686 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0505:Nwd2
|
UTSW |
5 |
63,962,454 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0655:Nwd2
|
UTSW |
5 |
63,948,928 (GRCm39) |
missense |
possibly damaging |
0.73 |
|
R0762:Nwd2
|
UTSW |
5 |
63,957,757 (GRCm39) |
missense |
probably benign |
0.33 |
|
R0835:Nwd2
|
UTSW |
5 |
63,957,473 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0926:Nwd2
|
UTSW |
5 |
63,965,234 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0948:Nwd2
|
UTSW |
5 |
63,964,655 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1015:Nwd2
|
UTSW |
5 |
63,964,154 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1086:Nwd2
|
UTSW |
5 |
63,963,917 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1186:Nwd2
|
UTSW |
5 |
63,807,367 (GRCm39) |
utr 5 prime |
probably benign |
|
|
R1305:Nwd2
|
UTSW |
5 |
63,902,540 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R1542:Nwd2
|
UTSW |
5 |
63,964,318 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1548:Nwd2
|
UTSW |
5 |
63,957,525 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1553:Nwd2
|
UTSW |
5 |
63,957,848 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1636:Nwd2
|
UTSW |
5 |
63,964,900 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1658:Nwd2
|
UTSW |
5 |
63,964,589 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1763:Nwd2
|
UTSW |
5 |
63,965,614 (GRCm39) |
missense |
probably benign |
|
|
R1800:Nwd2
|
UTSW |
5 |
63,962,917 (GRCm39) |
missense |
probably benign |
0.15 |
|
R1813:Nwd2
|
UTSW |
5 |
63,962,753 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1861:Nwd2
|
UTSW |
5 |
63,962,197 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R1889:Nwd2
|
UTSW |
5 |
63,965,009 (GRCm39) |
missense |
possibly damaging |
0.49 |
|
R1896:Nwd2
|
UTSW |
5 |
63,962,753 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1919:Nwd2
|
UTSW |
5 |
63,963,523 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1922:Nwd2
|
UTSW |
5 |
63,951,585 (GRCm39) |
missense |
probably benign |
|
|
R2258:Nwd2
|
UTSW |
5 |
63,962,499 (GRCm39) |
missense |
probably benign |
0.00 |
|
R2292:Nwd2
|
UTSW |
5 |
63,962,917 (GRCm39) |
missense |
probably benign |
0.15 |
|
R2504:Nwd2
|
UTSW |
5 |
63,961,717 (GRCm39) |
missense |
probably benign |
0.02 |
|
R2869:Nwd2
|
UTSW |
5 |
63,957,671 (GRCm39) |
missense |
probably benign |
0.00 |
|
R2869:Nwd2
|
UTSW |
5 |
63,957,671 (GRCm39) |
missense |
probably benign |
0.00 |
|
R2958:Nwd2
|
UTSW |
5 |
63,963,325 (GRCm39) |
missense |
probably benign |
0.01 |
|
R3034:Nwd2
|
UTSW |
5 |
63,957,446 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3422:Nwd2
|
UTSW |
5 |
63,882,536 (GRCm39) |
missense |
possibly damaging |
0.46 |
|
R3423:Nwd2
|
UTSW |
5 |
63,957,504 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3439:Nwd2
|
UTSW |
5 |
63,961,895 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4193:Nwd2
|
UTSW |
5 |
63,964,808 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4254:Nwd2
|
UTSW |
5 |
63,963,889 (GRCm39) |
missense |
possibly damaging |
0.74 |
|
R4384:Nwd2
|
UTSW |
5 |
63,963,914 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4707:Nwd2
|
UTSW |
5 |
63,951,665 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4713:Nwd2
|
UTSW |
5 |
63,961,803 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4735:Nwd2
|
UTSW |
5 |
63,965,594 (GRCm39) |
missense |
probably benign |
0.34 |
|
R4744:Nwd2
|
UTSW |
5 |
63,964,310 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4795:Nwd2
|
UTSW |
5 |
63,962,776 (GRCm39) |
missense |
probably benign |
0.21 |
|
R4835:Nwd2
|
UTSW |
5 |
63,965,189 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4839:Nwd2
|
UTSW |
5 |
63,962,893 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R4896:Nwd2
|
UTSW |
5 |
63,962,151 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5017:Nwd2
|
UTSW |
5 |
63,807,484 (GRCm39) |
utr 5 prime |
probably benign |
|
|
R5170:Nwd2
|
UTSW |
5 |
63,963,380 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5312:Nwd2
|
UTSW |
5 |
63,963,415 (GRCm39) |
nonsense |
probably null |
|
|
R5330:Nwd2
|
UTSW |
5 |
63,963,859 (GRCm39) |
missense |
probably benign |
0.02 |
|
R5331:Nwd2
|
UTSW |
5 |
63,963,859 (GRCm39) |
missense |
probably benign |
0.02 |
|
R5419:Nwd2
|
UTSW |
5 |
63,965,051 (GRCm39) |
missense |
probably benign |
0.11 |
|
R5434:Nwd2
|
UTSW |
5 |
63,964,991 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5445:Nwd2
|
UTSW |
5 |
63,962,681 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5761:Nwd2
|
UTSW |
5 |
63,882,573 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5788:Nwd2
|
UTSW |
5 |
63,965,114 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5907:Nwd2
|
UTSW |
5 |
63,963,326 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5959:Nwd2
|
UTSW |
5 |
63,965,413 (GRCm39) |
missense |
probably benign |
0.32 |
|
R6002:Nwd2
|
UTSW |
5 |
63,962,143 (GRCm39) |
missense |
probably benign |
|
|
R6027:Nwd2
|
UTSW |
5 |
63,965,563 (GRCm39) |
missense |
possibly damaging |
0.65 |
|
R6082:Nwd2
|
UTSW |
5 |
63,962,374 (GRCm39) |
missense |
possibly damaging |
0.96 |
|
R6163:Nwd2
|
UTSW |
5 |
63,963,131 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6172:Nwd2
|
UTSW |
5 |
63,964,249 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R6334:Nwd2
|
UTSW |
5 |
63,957,596 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R6447:Nwd2
|
UTSW |
5 |
63,964,898 (GRCm39) |
missense |
probably benign |
0.41 |
|
R6649:Nwd2
|
UTSW |
5 |
63,882,527 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R6855:Nwd2
|
UTSW |
5 |
63,961,794 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7034:Nwd2
|
UTSW |
5 |
63,962,258 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7168:Nwd2
|
UTSW |
5 |
63,964,837 (GRCm39) |
missense |
probably benign |
0.04 |
|
R7326:Nwd2
|
UTSW |
5 |
63,957,752 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7561:Nwd2
|
UTSW |
5 |
63,964,434 (GRCm39) |
nonsense |
probably null |
|
|
R7576:Nwd2
|
UTSW |
5 |
63,964,736 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7580:Nwd2
|
UTSW |
5 |
63,965,624 (GRCm39) |
missense |
probably benign |
0.05 |
|
R7723:Nwd2
|
UTSW |
5 |
63,965,347 (GRCm39) |
missense |
possibly damaging |
0.69 |
|
R7769:Nwd2
|
UTSW |
5 |
63,961,847 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8293:Nwd2
|
UTSW |
5 |
63,962,663 (GRCm39) |
missense |
probably benign |
0.05 |
|
R8517:Nwd2
|
UTSW |
5 |
63,948,925 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8782:Nwd2
|
UTSW |
5 |
63,882,540 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8792:Nwd2
|
UTSW |
5 |
63,963,047 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R8888:Nwd2
|
UTSW |
5 |
63,963,241 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8895:Nwd2
|
UTSW |
5 |
63,963,241 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8901:Nwd2
|
UTSW |
5 |
63,963,685 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8913:Nwd2
|
UTSW |
5 |
63,963,440 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
R8920:Nwd2
|
UTSW |
5 |
63,948,863 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9052:Nwd2
|
UTSW |
5 |
63,961,773 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9362:Nwd2
|
UTSW |
5 |
63,961,747 (GRCm39) |
missense |
probably benign |
0.23 |
|
R9368:Nwd2
|
UTSW |
5 |
63,962,306 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9377:Nwd2
|
UTSW |
5 |
63,957,740 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9430:Nwd2
|
UTSW |
5 |
63,964,665 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9655:Nwd2
|
UTSW |
5 |
63,964,568 (GRCm39) |
nonsense |
probably null |
|
|
R9661:Nwd2
|
UTSW |
5 |
63,957,780 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R9736:Nwd2
|
UTSW |
5 |
63,951,600 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9793:Nwd2
|
UTSW |
5 |
63,964,232 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9795:Nwd2
|
UTSW |
5 |
63,964,232 (GRCm39) |
missense |
probably damaging |
1.00 |
|
RF020:Nwd2
|
UTSW |
5 |
63,963,066 (GRCm39) |
nonsense |
probably null |
|
|
X0023:Nwd2
|
UTSW |
5 |
63,964,306 (GRCm39) |
missense |
probably damaging |
0.99 |
|
Z1176:Nwd2
|
UTSW |
5 |
63,963,500 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1176:Nwd2
|
UTSW |
5 |
63,882,540 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1177:Nwd2
|
UTSW |
5 |
63,964,669 (GRCm39) |
nonsense |
probably null |
|
|
Z1177:Nwd2
|
UTSW |
5 |
63,962,327 (GRCm39) |
missense |
possibly damaging |
0.60 |
|
| Predicted Primers |
PCR Primer
(F):5'- TGTCTTTGTCAACCAGTGGCGTTC -3'
(R):5'- ATGGTGATCCCATCCTCACAGCAG -3'
Sequencing Primer
(F):5'- AACCCATTCAGAGTCTGGTG -3'
(R):5'- AGACTGACTGCCAGCACTTTG -3'
|
| Posted On |
2013-04-16 |
Incidental Mutation