Incidental Mutation 'R2509:Ift172'
| ID |
251715 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Ift172
|
| Ensembl Gene |
ENSMUSG00000038564 |
| Gene Name |
intraflagellar transport 172 |
| Synonyms |
4930553F24Rik, wim, avc1 |
| MMRRC Submission |
040415-MU
|
| Accession Numbers |
|
| Essential gene? |
Essential
(E-score: 1.000)
|
| Stock # |
R2509 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
|
| Chromosome |
5 |
| Chromosomal Location |
31410623-31448458 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to C
at 31420312 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Asparagine to Serine
at position 1108
(N1108S)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000049335
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000041565]
|
| AlphaFold |
Q6VH22 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000041565
AA Change: N1108S
PolyPhen 2
Score 0.000 (Sensitivity: 1.00; Specificity: 0.00)
|
| SMART Domains |
Protein: ENSMUSP00000049335
Gene: ENSMUSG00000038564
AA Change: N1108S
| Domain | Start | End | E-Value | Type |
|---|
|
WD40
|
2 |
44 |
6e-3 |
SMART |
|
WD40
|
55 |
94 |
2.22e0 |
SMART |
|
WD40
|
102 |
139 |
1.23e2 |
SMART |
|
WD40
|
141 |
180 |
4.6e0 |
SMART |
|
WD40
|
186 |
223 |
3.3e1 |
SMART |
|
WD40
|
225 |
267 |
4.42e1 |
SMART |
|
WD40
|
279 |
314 |
1.03e1 |
SMART |
|
Blast:WD40
|
516 |
550 |
5e-13 |
BLAST |
|
low complexity region
|
573 |
588 |
N/A |
INTRINSIC |
|
internal_repeat_1
|
625 |
1026 |
1.7e-10 |
PROSPERO |
|
Blast:TPR
|
1029 |
1062 |
2e-13 |
BLAST |
|
low complexity region
|
1077 |
1091 |
N/A |
INTRINSIC |
|
internal_repeat_1
|
1101 |
1498 |
1.7e-10 |
PROSPERO |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000200936
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000201057
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000201953
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000202585
|
| SMART Domains |
Protein: ENSMUSP00000144216
Gene: ENSMUSG00000038564
| Domain | Start | End | E-Value | Type |
|---|
|
Blast:WD40
|
46 |
78 |
2e-11 |
BLAST |
|
| Meta Mutation Damage Score |
0.0639 |
| Coding Region Coverage |
- 1x: 99.2%
- 3x: 98.6%
- 10x: 97.4%
- 20x: 95.4%
|
| Validation Efficiency |
96% (105/109) |
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a subunit of the intraflagellar transport subcomplex IFT-B. Subcomplexes IFT-A and IFT-B are necessary for ciliary assembly and maintenance. Mutations in this gene have been associated with skeletal ciliopathies, with or without polydactyly, such as such short-rib thoracic dysplasias 1, 9 or 10. [provided by RefSeq, Mar 2014]
PHENOTYPE: Mice homozygous for disruptions in this gene display embryonic lethality during organogenesis, neural tube defects, and developmental patterning abnormalities. Mice homozygous for a conditional allele activated in the early limb bud exhibit polydactyly and short limbs. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 108 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 1700006A11Rik |
T |
C |
3: 124,200,102 (GRCm39) |
I497V |
probably benign |
Het |
| 4930571K23Rik |
C |
A |
7: 124,968,311 (GRCm39) |
|
noncoding transcript |
Het |
| Abca17 |
G |
T |
17: 24,508,587 (GRCm39) |
|
probably benign |
Het |
| Ablim1 |
C |
T |
19: 57,140,791 (GRCm39) |
R196Q |
probably damaging |
Het |
| Acot11 |
T |
C |
4: 106,612,516 (GRCm39) |
I379V |
possibly damaging |
Het |
| Acot4 |
G |
A |
12: 84,088,647 (GRCm39) |
G165D |
probably damaging |
Het |
| Agrn |
A |
T |
4: 156,250,881 (GRCm39) |
|
probably null |
Het |
| Ahctf1 |
T |
C |
1: 179,598,258 (GRCm39) |
S945G |
possibly damaging |
Het |
| Akr1c13 |
C |
T |
13: 4,248,583 (GRCm39) |
R263C |
probably damaging |
Het |
| Arfgap1 |
T |
A |
2: 180,615,846 (GRCm39) |
|
probably benign |
Het |
| Arhgef3 |
A |
G |
14: 27,101,633 (GRCm39) |
K103R |
probably damaging |
Het |
| Cabp1 |
A |
T |
5: 115,310,843 (GRCm39) |
N211K |
probably damaging |
Het |
| Cacna1c |
T |
A |
6: 118,711,943 (GRCm39) |
D261V |
probably damaging |
Het |
| Car11 |
G |
A |
7: 45,350,783 (GRCm39) |
G93E |
probably damaging |
Het |
| Card10 |
A |
G |
15: 78,664,473 (GRCm39) |
I821T |
probably benign |
Het |
| Cast |
T |
C |
13: 74,885,735 (GRCm39) |
I277V |
probably benign |
Het |
| Cenpj |
T |
C |
14: 56,769,694 (GRCm39) |
K1165R |
probably null |
Het |
| Cenpk |
A |
G |
13: 104,370,675 (GRCm39) |
|
probably null |
Het |
| Cfap251 |
A |
G |
5: 123,394,169 (GRCm39) |
K353E |
probably benign |
Het |
| Cmya5 |
T |
C |
13: 93,230,066 (GRCm39) |
Q1674R |
probably benign |
Het |
| Cnnm1 |
T |
A |
19: 43,430,325 (GRCm39) |
V481D |
probably damaging |
Het |
| Cracdl |
T |
C |
1: 37,664,381 (GRCm39) |
M506V |
probably benign |
Het |
| Csmd3 |
CCTTTGCGCTT |
CCTT |
15: 47,604,632 (GRCm39) |
|
probably null |
Het |
| Cyp2c50 |
G |
A |
19: 40,079,013 (GRCm39) |
V119I |
probably benign |
Het |
| Dnah7b |
A |
G |
1: 46,234,447 (GRCm39) |
T1460A |
probably damaging |
Het |
| Dnah8 |
G |
A |
17: 30,994,019 (GRCm39) |
D3379N |
probably benign |
Het |
| Dnajc4 |
C |
T |
19: 6,968,111 (GRCm39) |
R55H |
probably damaging |
Het |
| Ebf4 |
C |
T |
2: 130,148,482 (GRCm39) |
R98* |
probably null |
Het |
| Epha4 |
G |
A |
1: 77,488,339 (GRCm39) |
A47V |
possibly damaging |
Het |
| Ercc8 |
T |
C |
13: 108,320,251 (GRCm39) |
|
probably benign |
Het |
| Exo1 |
T |
C |
1: 175,733,399 (GRCm39) |
F75S |
probably damaging |
Het |
| Fam168a |
G |
T |
7: 100,483,391 (GRCm39) |
|
probably null |
Het |
| Fat3 |
G |
A |
9: 15,836,310 (GRCm39) |
R4065W |
possibly damaging |
Het |
| Gm5431 |
T |
A |
11: 48,779,536 (GRCm39) |
N740I |
probably benign |
Het |
| Gm5900 |
T |
A |
7: 104,599,571 (GRCm39) |
|
noncoding transcript |
Het |
| Gpi1 |
A |
G |
7: 33,905,348 (GRCm39) |
S359P |
probably damaging |
Het |
| Gpr156 |
A |
G |
16: 37,768,149 (GRCm39) |
R22G |
probably benign |
Het |
| Greb1 |
A |
G |
12: 16,774,923 (GRCm39) |
V158A |
probably damaging |
Het |
| Grin2c |
T |
A |
11: 115,141,894 (GRCm39) |
K842* |
probably null |
Het |
| Gsta5 |
T |
A |
9: 78,202,089 (GRCm39) |
M1K |
probably null |
Het |
| Hnf4a |
T |
A |
2: 163,408,161 (GRCm39) |
L329Q |
probably damaging |
Het |
| Hsp90ab1 |
A |
G |
17: 45,880,267 (GRCm39) |
L92P |
probably damaging |
Het |
| Ido1 |
T |
A |
8: 25,074,501 (GRCm39) |
R290* |
probably null |
Het |
| Ifnlr1 |
G |
T |
4: 135,432,559 (GRCm39) |
D332Y |
probably damaging |
Het |
| Igkv3-9 |
T |
A |
6: 70,565,728 (GRCm39) |
M109K |
probably benign |
Het |
| Igsf10 |
T |
C |
3: 59,239,287 (GRCm39) |
D298G |
probably damaging |
Het |
| Iqck |
T |
G |
7: 118,475,505 (GRCm39) |
M98R |
probably benign |
Het |
| Klk1b1 |
T |
C |
7: 43,618,803 (GRCm39) |
V60A |
probably damaging |
Het |
| Krtap1-3 |
C |
T |
11: 99,481,653 (GRCm39) |
E165K |
unknown |
Het |
| Lair1 |
A |
G |
7: 4,013,782 (GRCm39) |
L155P |
probably damaging |
Het |
| Maco1 |
A |
G |
4: 134,531,699 (GRCm39) |
S657P |
probably damaging |
Het |
| Mast4 |
G |
T |
13: 102,990,350 (GRCm39) |
S57Y |
probably damaging |
Het |
| Mical3 |
T |
C |
6: 121,011,118 (GRCm39) |
H360R |
probably damaging |
Het |
| Muc5b |
A |
T |
7: 141,412,798 (GRCm39) |
N1915Y |
unknown |
Het |
| Myh1 |
A |
G |
11: 67,096,423 (GRCm39) |
I301V |
probably benign |
Het |
| Nck2 |
T |
A |
1: 43,593,393 (GRCm39) |
V200E |
probably damaging |
Het |
| Odad4 |
T |
G |
11: 100,444,361 (GRCm39) |
L222R |
probably damaging |
Het |
| Or2y1b |
T |
G |
11: 49,209,048 (GRCm39) |
L225R |
probably damaging |
Het |
| Or4b12 |
T |
C |
2: 90,096,030 (GRCm39) |
Y248C |
possibly damaging |
Het |
| Or4c109 |
T |
G |
2: 88,817,775 (GRCm39) |
Y257S |
probably damaging |
Het |
| Or4f60 |
T |
A |
2: 111,902,837 (GRCm39) |
L30F |
probably benign |
Het |
| Or4k38 |
C |
T |
2: 111,166,076 (GRCm39) |
V116I |
probably damaging |
Het |
| Or52n2c |
G |
A |
7: 104,574,894 (GRCm39) |
H26Y |
probably benign |
Het |
| Or5b101 |
T |
A |
19: 13,005,058 (GRCm39) |
I212F |
probably damaging |
Het |
| Or8b12i |
A |
G |
9: 20,082,525 (GRCm39) |
L114P |
probably damaging |
Het |
| Otoa |
C |
T |
7: 120,759,695 (GRCm39) |
T1099I |
probably benign |
Het |
| Pask |
T |
A |
1: 93,258,485 (GRCm39) |
I288F |
possibly damaging |
Het |
| Pcnx4 |
T |
C |
12: 72,613,746 (GRCm39) |
W564R |
probably damaging |
Het |
| Pip4p1 |
A |
T |
14: 51,167,115 (GRCm39) |
Y129* |
probably null |
Het |
| Pitpnm2 |
T |
C |
5: 124,274,389 (GRCm39) |
E240G |
probably damaging |
Het |
| Ppp1r16b |
A |
G |
2: 158,603,383 (GRCm39) |
Y436C |
possibly damaging |
Het |
| Pramel27 |
G |
A |
4: 143,578,561 (GRCm39) |
V274I |
probably benign |
Het |
| Prkca |
T |
C |
11: 107,870,032 (GRCm39) |
Y37C |
probably damaging |
Het |
| Rad18 |
T |
G |
6: 112,652,883 (GRCm39) |
H238P |
possibly damaging |
Het |
| Rap1b |
T |
A |
10: 117,654,444 (GRCm39) |
Q1L |
probably damaging |
Het |
| Rgs9 |
T |
C |
11: 109,159,798 (GRCm39) |
Y178C |
probably benign |
Het |
| Rpl3l |
A |
T |
17: 24,951,360 (GRCm39) |
D87V |
possibly damaging |
Het |
| Scrn2 |
T |
C |
11: 96,923,992 (GRCm39) |
V292A |
possibly damaging |
Het |
| Sdad1 |
A |
G |
5: 92,453,684 (GRCm39) |
Y35H |
probably benign |
Het |
| Sez6l2 |
T |
C |
7: 126,552,944 (GRCm39) |
S177P |
probably benign |
Het |
| Sh3bp1 |
C |
T |
15: 78,795,706 (GRCm39) |
P612S |
probably damaging |
Het |
| Shank1 |
T |
C |
7: 44,001,148 (GRCm39) |
S956P |
unknown |
Het |
| Shank1 |
G |
A |
7: 44,001,547 (GRCm39) |
A1089T |
unknown |
Het |
| Shprh |
G |
A |
10: 11,042,468 (GRCm39) |
C817Y |
probably damaging |
Het |
| Spata22 |
C |
T |
11: 73,236,593 (GRCm39) |
P300S |
probably damaging |
Het |
| Sstr2 |
A |
T |
11: 113,515,749 (GRCm39) |
I223F |
probably damaging |
Het |
| Stom |
C |
T |
2: 35,210,354 (GRCm39) |
A217T |
probably damaging |
Het |
| Stpg1 |
T |
C |
4: 135,263,960 (GRCm39) |
V341A |
probably benign |
Het |
| Tagap |
A |
G |
17: 8,147,586 (GRCm39) |
T99A |
probably benign |
Het |
| Tas1r2 |
A |
G |
4: 139,387,162 (GRCm39) |
N207S |
probably damaging |
Het |
| Thbs2 |
A |
G |
17: 14,906,105 (GRCm39) |
V265A |
probably benign |
Het |
| Thyn1 |
A |
G |
9: 26,911,316 (GRCm39) |
R3G |
possibly damaging |
Het |
| Tia1 |
T |
A |
6: 86,401,312 (GRCm39) |
|
probably null |
Het |
| Tktl2 |
A |
G |
8: 66,965,504 (GRCm39) |
E354G |
probably benign |
Het |
| Tmc8 |
A |
G |
11: 117,683,511 (GRCm39) |
T689A |
possibly damaging |
Het |
| Tmem11 |
A |
T |
11: 60,755,807 (GRCm39) |
|
probably null |
Het |
| Tnik |
T |
C |
3: 28,722,064 (GRCm39) |
V1310A |
probably damaging |
Het |
| Trappc10 |
A |
G |
10: 78,047,357 (GRCm39) |
S380P |
possibly damaging |
Het |
| Trim8 |
C |
T |
19: 46,503,734 (GRCm39) |
P429S |
probably benign |
Het |
| Ttn |
C |
A |
2: 76,687,756 (GRCm39) |
|
probably benign |
Het |
| Ulk2 |
T |
C |
11: 61,678,340 (GRCm39) |
Y793C |
probably benign |
Het |
| Vill |
G |
A |
9: 118,899,370 (GRCm39) |
V337M |
possibly damaging |
Het |
| Vps53 |
C |
A |
11: 75,957,661 (GRCm39) |
V364F |
possibly damaging |
Het |
| Zan |
A |
T |
5: 137,454,848 (GRCm39) |
I1396N |
unknown |
Het |
| Zfa-ps |
A |
C |
10: 52,420,339 (GRCm39) |
|
noncoding transcript |
Het |
| Zfp426 |
T |
C |
9: 20,381,977 (GRCm39) |
T337A |
possibly damaging |
Het |
| Zfp536 |
T |
C |
7: 37,267,403 (GRCm39) |
E671G |
possibly damaging |
Het |
| Zfp985 |
A |
G |
4: 147,667,443 (GRCm39) |
T104A |
possibly damaging |
Het |
|
| Other mutations in Ift172 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00476:Ift172
|
APN |
5 |
31,433,240 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01399:Ift172
|
APN |
5 |
31,423,592 (GRCm39) |
missense |
probably benign |
|
|
IGL01405:Ift172
|
APN |
5 |
31,419,196 (GRCm39) |
nonsense |
probably null |
|
|
IGL01562:Ift172
|
APN |
5 |
31,424,591 (GRCm39) |
missense |
probably damaging |
0.97 |
|
IGL01758:Ift172
|
APN |
5 |
31,438,058 (GRCm39) |
missense |
probably benign |
|
|
IGL01792:Ift172
|
APN |
5 |
31,434,215 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01830:Ift172
|
APN |
5 |
31,442,636 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01839:Ift172
|
APN |
5 |
31,423,694 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02007:Ift172
|
APN |
5 |
31,443,948 (GRCm39) |
missense |
probably benign |
0.17 |
|
IGL02172:Ift172
|
APN |
5 |
31,438,681 (GRCm39) |
splice site |
probably benign |
|
|
IGL02190:Ift172
|
APN |
5 |
31,411,802 (GRCm39) |
missense |
possibly damaging |
0.51 |
|
IGL02334:Ift172
|
APN |
5 |
31,440,402 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL02486:Ift172
|
APN |
5 |
31,414,927 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02517:Ift172
|
APN |
5 |
31,410,992 (GRCm39) |
splice site |
probably null |
|
|
IGL02571:Ift172
|
APN |
5 |
31,415,235 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02626:Ift172
|
APN |
5 |
31,421,840 (GRCm39) |
missense |
probably benign |
|
|
IGL03183:Ift172
|
APN |
5 |
31,429,348 (GRCm39) |
missense |
probably benign |
0.06 |
|
IGL03277:Ift172
|
APN |
5 |
31,424,642 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
IGL03349:Ift172
|
APN |
5 |
31,441,474 (GRCm39) |
missense |
probably benign |
0.05 |
|
ostinato
|
UTSW |
5 |
31,434,284 (GRCm39) |
missense |
probably benign |
0.10 |
|
pushback
|
UTSW |
5 |
31,444,289 (GRCm39) |
missense |
probably damaging |
1.00 |
|
P0042:Ift172
|
UTSW |
5 |
31,418,799 (GRCm39) |
missense |
probably benign |
0.35 |
|
PIT4802001:Ift172
|
UTSW |
5 |
31,442,610 (GRCm39) |
missense |
probably benign |
0.03 |
|
R0153:Ift172
|
UTSW |
5 |
31,417,968 (GRCm39) |
missense |
probably benign |
|
|
R0328:Ift172
|
UTSW |
5 |
31,421,195 (GRCm39) |
nonsense |
probably null |
|
|
R0357:Ift172
|
UTSW |
5 |
31,415,244 (GRCm39) |
missense |
possibly damaging |
0.51 |
|
R0369:Ift172
|
UTSW |
5 |
31,410,985 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0391:Ift172
|
UTSW |
5 |
31,444,011 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0512:Ift172
|
UTSW |
5 |
31,442,821 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R0546:Ift172
|
UTSW |
5 |
31,414,945 (GRCm39) |
missense |
probably benign |
0.14 |
|
R0553:Ift172
|
UTSW |
5 |
31,433,186 (GRCm39) |
splice site |
probably benign |
|
|
R0606:Ift172
|
UTSW |
5 |
31,411,657 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0834:Ift172
|
UTSW |
5 |
31,414,715 (GRCm39) |
missense |
probably benign |
|
|
R0973:Ift172
|
UTSW |
5 |
31,415,262 (GRCm39) |
unclassified |
probably benign |
|
|
R0973:Ift172
|
UTSW |
5 |
31,422,699 (GRCm39) |
missense |
probably benign |
|
|
R1189:Ift172
|
UTSW |
5 |
31,443,174 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R1205:Ift172
|
UTSW |
5 |
31,443,136 (GRCm39) |
missense |
probably benign |
|
|
R1289:Ift172
|
UTSW |
5 |
31,438,320 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R1342:Ift172
|
UTSW |
5 |
31,419,210 (GRCm39) |
missense |
probably benign |
|
|
R1395:Ift172
|
UTSW |
5 |
31,442,582 (GRCm39) |
unclassified |
probably benign |
|
|
R1417:Ift172
|
UTSW |
5 |
31,413,993 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2020:Ift172
|
UTSW |
5 |
31,424,585 (GRCm39) |
nonsense |
probably null |
|
|
R2111:Ift172
|
UTSW |
5 |
31,443,423 (GRCm39) |
missense |
probably benign |
0.04 |
|
R2175:Ift172
|
UTSW |
5 |
31,424,029 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2870:Ift172
|
UTSW |
5 |
31,415,205 (GRCm39) |
missense |
probably benign |
0.00 |
|
R2870:Ift172
|
UTSW |
5 |
31,415,205 (GRCm39) |
missense |
probably benign |
0.00 |
|
R2871:Ift172
|
UTSW |
5 |
31,415,205 (GRCm39) |
missense |
probably benign |
0.00 |
|
R2871:Ift172
|
UTSW |
5 |
31,415,205 (GRCm39) |
missense |
probably benign |
0.00 |
|
R2872:Ift172
|
UTSW |
5 |
31,415,205 (GRCm39) |
missense |
probably benign |
0.00 |
|
R2872:Ift172
|
UTSW |
5 |
31,415,205 (GRCm39) |
missense |
probably benign |
0.00 |
|
R3705:Ift172
|
UTSW |
5 |
31,418,781 (GRCm39) |
critical splice donor site |
probably null |
|
|
R3793:Ift172
|
UTSW |
5 |
31,414,925 (GRCm39) |
missense |
possibly damaging |
0.61 |
|
R4385:Ift172
|
UTSW |
5 |
31,444,311 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4477:Ift172
|
UTSW |
5 |
31,422,781 (GRCm39) |
missense |
probably benign |
0.38 |
|
R4590:Ift172
|
UTSW |
5 |
31,411,299 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4663:Ift172
|
UTSW |
5 |
31,441,559 (GRCm39) |
missense |
probably benign |
0.01 |
|
R4665:Ift172
|
UTSW |
5 |
31,442,598 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
R4977:Ift172
|
UTSW |
5 |
31,429,460 (GRCm39) |
missense |
possibly damaging |
0.79 |
|
R5109:Ift172
|
UTSW |
5 |
31,423,330 (GRCm39) |
missense |
probably benign |
0.06 |
|
R5182:Ift172
|
UTSW |
5 |
31,424,958 (GRCm39) |
missense |
possibly damaging |
0.51 |
|
R5343:Ift172
|
UTSW |
5 |
31,421,156 (GRCm39) |
missense |
probably benign |
0.05 |
|
R5465:Ift172
|
UTSW |
5 |
31,418,862 (GRCm39) |
splice site |
probably null |
|
|
R5622:Ift172
|
UTSW |
5 |
31,440,426 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5718:Ift172
|
UTSW |
5 |
31,412,621 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R5793:Ift172
|
UTSW |
5 |
31,434,292 (GRCm39) |
missense |
possibly damaging |
0.96 |
|
R5870:Ift172
|
UTSW |
5 |
31,434,284 (GRCm39) |
missense |
probably benign |
0.10 |
|
R5919:Ift172
|
UTSW |
5 |
31,418,006 (GRCm39) |
missense |
possibly damaging |
0.63 |
|
R5968:Ift172
|
UTSW |
5 |
31,418,828 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6112:Ift172
|
UTSW |
5 |
31,414,241 (GRCm39) |
missense |
probably benign |
|
|
R6339:Ift172
|
UTSW |
5 |
31,444,289 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6339:Ift172
|
UTSW |
5 |
31,413,927 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6355:Ift172
|
UTSW |
5 |
31,441,501 (GRCm39) |
missense |
probably benign |
0.33 |
|
R6565:Ift172
|
UTSW |
5 |
31,433,227 (GRCm39) |
missense |
possibly damaging |
0.68 |
|
R6668:Ift172
|
UTSW |
5 |
31,412,683 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6755:Ift172
|
UTSW |
5 |
31,418,342 (GRCm39) |
nonsense |
probably null |
|
|
R6818:Ift172
|
UTSW |
5 |
31,423,304 (GRCm39) |
missense |
probably benign |
0.01 |
|
R6939:Ift172
|
UTSW |
5 |
31,414,930 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6980:Ift172
|
UTSW |
5 |
31,414,730 (GRCm39) |
missense |
probably benign |
|
|
R7047:Ift172
|
UTSW |
5 |
31,433,238 (GRCm39) |
nonsense |
probably null |
|
|
R7156:Ift172
|
UTSW |
5 |
31,429,419 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7180:Ift172
|
UTSW |
5 |
31,411,606 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7288:Ift172
|
UTSW |
5 |
31,442,630 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7351:Ift172
|
UTSW |
5 |
31,433,240 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7706:Ift172
|
UTSW |
5 |
31,423,723 (GRCm39) |
nonsense |
probably null |
|
|
R7890:Ift172
|
UTSW |
5 |
31,440,425 (GRCm39) |
nonsense |
probably null |
|
|
R7980:Ift172
|
UTSW |
5 |
31,417,988 (GRCm39) |
missense |
probably benign |
|
|
R8263:Ift172
|
UTSW |
5 |
31,422,681 (GRCm39) |
missense |
possibly damaging |
0.48 |
|
R8559:Ift172
|
UTSW |
5 |
31,413,921 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R8717:Ift172
|
UTSW |
5 |
31,412,985 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8774:Ift172
|
UTSW |
5 |
31,415,207 (GRCm39) |
missense |
probably benign |
0.45 |
|
R8774-TAIL:Ift172
|
UTSW |
5 |
31,415,207 (GRCm39) |
missense |
probably benign |
0.45 |
|
R9037:Ift172
|
UTSW |
5 |
31,420,400 (GRCm39) |
missense |
possibly damaging |
0.56 |
|
R9038:Ift172
|
UTSW |
5 |
31,441,399 (GRCm39) |
missense |
possibly damaging |
0.53 |
|
R9133:Ift172
|
UTSW |
5 |
31,442,867 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9607:Ift172
|
UTSW |
5 |
31,410,913 (GRCm39) |
missense |
|
|
|
X0022:Ift172
|
UTSW |
5 |
31,442,664 (GRCm39) |
missense |
probably damaging |
0.97 |
|
Z1176:Ift172
|
UTSW |
5 |
31,434,268 (GRCm39) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- ACTTTTGCCTCAGCTTTTGGAG -3'
(R):5'- GTTTAGAGACCCGACACTTGG -3'
Sequencing Primer
(F):5'- GCCTCAGCTTTTGGAGTTATTTTTC -3'
(R):5'- TGATTAGCAGCAGGGTCCTGAC -3'
|
| Posted On |
2014-12-04 |
Incidental Mutation