Mutagenetix > Incidental Mutation

Incidental Mutation 'R2871:Hmcn1'

253668

Institutional Source

Beutler Lab

Gene Symbol

Hmcn1

Ensembl Gene

ENSMUSG00000066842

Gene Name

hemicentin 1

Synonyms

EG545370, LOC240793

MMRRC Submission

040459-MU

Accession Numbers

Essential gene?

Non essential (E-score: 0.000) question?

Stock #

R2871 (G1)

Quality Score

225

Status

Not validated

Chromosome

Chromosomal Location

150438275-150869186 bp(-) (GRCm39)

Type of Mutation

missense

DNA Base Change (assembly)

A to T at 150614467 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Valine to Aspartic acid at position 1313 (V1313D)

Ref Sequence

ENSEMBL: ENSMUSP00000121500 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000074783] [ENSMUST00000137197]

AlphaFold

no structure available at present

Predicted Effect

probably benign
Transcript: ENSMUST00000074783
AA Change: V1313D

PolyPhen 2 Score 0.189 (Sensitivity: 0.92; Specificity: 0.87)

SMART Domains

Protein: ENSMUSP00000074340
Gene: ENSMUSG00000066842
AA Change: V1313D

Domain	Start	End	E-Value	Type
signal peptide	1	21	N/A	INTRINSIC
VWA	39	213	3e-1	SMART
IG_like	445	506	1.13e0	SMART
IGc2	532	598	2.32e-8	SMART
IGc2	624	688	1.24e-8	SMART
IGc2	714	779	7.52e-8	SMART
IGc2	805	874	2.19e-9	SMART
IGc2	902	967	5.15e-15	SMART
IGc2	993	1058	1.28e-10	SMART
IGc2	1092	1157	1.69e-10	SMART
IGc2	1183	1247	1.09e-13	SMART
IGc2	1278	1344	6.49e-12	SMART
IGc2	1372	1437	5.2e-11	SMART
IGc2	1465	1531	1.34e-13	SMART
IGc2	1559	1624	6.25e-14	SMART
IGc2	1653	1718	4.06e-13	SMART
IGc2	1746	1811	4.12e-14	SMART
IGc2	1838	1904	5.92e-15	SMART
IGc2	1932	1997	7.69e-14	SMART
IGc2	2023	2089	3.3e-13	SMART
IGc2	2115	2180	5e-13	SMART
IGc2	2208	2275	1.32e-12	SMART
IGc2	2304	2369	2.91e-14	SMART
IGc2	2398	2463	4e-12	SMART
IGc2	2491	2556	1.94e-19	SMART
IGc2	2587	2652	2.54e-14	SMART
IGc2	2686	2751	7.57e-13	SMART
IGc2	2789	2854	4.88e-16	SMART
IGc2	2884	2949	2.7e-9	SMART
IGc2	2976	3041	1.47e-10	SMART
IGc2	3071	3136	2.24e-15	SMART
IGc2	3163	3230	8.83e-14	SMART
IGc2	3258	3325	9.76e-16	SMART
IGc2	3354	3419	1.54e-13	SMART
IGc2	3447	3512	4.35e-13	SMART
IGc2	3540	3605	2e-12	SMART
IGc2	3633	3698	7.69e-14	SMART
IGc2	3724	3789	1.92e-14	SMART
IGc2	3815	3882	2.58e-6	SMART
IGc2	3908	3973	6.4e-11	SMART
IGc2	3999	4064	2.78e-11	SMART
IGc2	4090	4154	1.74e-12	SMART
low complexity region	4155	4160	N/A	INTRINSIC
IGc2	4180	4245	3.35e-14	SMART
IGc2	4271	4334	8.12e-13	SMART
IGc2	4361	4425	1.79e-14	SMART
IGc2	4451	4515	1.06e-11	SMART
TSP1	4531	4583	4.72e-15	SMART
TSP1	4588	4640	2.39e-16	SMART
TSP1	4645	4697	1.67e-15	SMART
TSP1	4702	4754	2.2e-15	SMART
TSP1	4759	4811	2.77e-12	SMART
TSP1	4816	4868	2.67e-14	SMART
Pfam:G2F	4869	5051	1.5e-57	PFAM
EGF_CA	5106	5145	4.38e-11	SMART
EGF_CA	5146	5190	4.49e-8	SMART
EGF_CA	5191	5228	2.38e-12	SMART
EGF_CA	5229	5270	6.8e-8	SMART
EGF_CA	5271	5313	3.51e-10	SMART
EGF_CA	5314	5354	4.32e-10	SMART
low complexity region	5384	5400	N/A	INTRINSIC
low complexity region	5401	5412	N/A	INTRINSIC
EGF_CA	5431	5470	2.78e-13	SMART
EGF	5474	5516	1.44e1	SMART

Predicted Effect

possibly damaging
Transcript: ENSMUST00000137197
AA Change: V1313D

PolyPhen 2 Score 0.952 (Sensitivity: 0.79; Specificity: 0.95)

SMART Domains

Protein: ENSMUSP00000121500
Gene: ENSMUSG00000066842
AA Change: V1313D

Domain	Start	End	E-Value	Type
signal peptide	1	21	N/A	INTRINSIC
VWA	39	213	3e-1	SMART
IG_like	445	506	1.13e0	SMART
IGc2	532	598	2.32e-8	SMART
IGc2	624	688	1.24e-8	SMART
IGc2	714	779	7.52e-8	SMART
IGc2	805	874	2.19e-9	SMART
IGc2	902	967	5.15e-15	SMART
IGc2	993	1058	1.28e-10	SMART
IGc2	1092	1157	1.69e-10	SMART
IGc2	1183	1247	1.09e-13	SMART
IGc2	1278	1344	6.49e-12	SMART
IGc2	1372	1437	5.2e-11	SMART
IGc2	1465	1531	1.34e-13	SMART
IGc2	1559	1624	6.25e-14	SMART
IGc2	1653	1718	4.06e-13	SMART
IGc2	1746	1811	4.12e-14	SMART
IGc2	1838	1904	5.92e-15	SMART
IGc2	1932	1997	7.69e-14	SMART
IGc2	2023	2089	3.3e-13	SMART
IGc2	2115	2180	5e-13	SMART
IGc2	2208	2275	1.32e-12	SMART
IGc2	2304	2369	2.91e-14	SMART
IGc2	2398	2463	4e-12	SMART
IGc2	2491	2556	1.94e-19	SMART
IGc2	2587	2652	2.54e-14	SMART
IGc2	2686	2751	7.57e-13	SMART
IGc2	2789	2854	4.88e-16	SMART
IGc2	2884	2949	2.7e-9	SMART
IGc2	2976	3041	1.47e-10	SMART
IGc2	3071	3136	2.24e-15	SMART
IGc2	3163	3230	8.83e-14	SMART
IGc2	3258	3325	9.76e-16	SMART
IGc2	3354	3419	1.54e-13	SMART
IGc2	3447	3512	4.35e-13	SMART
IGc2	3540	3605	2e-12	SMART
IGc2	3633	3698	7.69e-14	SMART
IGc2	3724	3789	1.92e-14	SMART
IGc2	3815	3882	2.58e-6	SMART
IGc2	3908	3973	6.4e-11	SMART
IGc2	3999	4064	2.78e-11	SMART
IGc2	4090	4154	1.74e-12	SMART
low complexity region	4155	4160	N/A	INTRINSIC
IGc2	4180	4245	3.35e-14	SMART
IGc2	4271	4334	8.12e-13	SMART
IGc2	4361	4425	1.79e-14	SMART
IGc2	4451	4515	1.06e-11	SMART
TSP1	4531	4583	4.72e-15	SMART
TSP1	4588	4640	2.39e-16	SMART
TSP1	4645	4697	1.67e-15	SMART
TSP1	4702	4754	2.2e-15	SMART
TSP1	4759	4811	2.77e-12	SMART
TSP1	4816	4868	2.67e-14	SMART
PDB:1GL4\|A	4869	5082	3e-6	PDB
SCOP:d1gl4a1	4869	5082	3e-79	SMART
EGF_CA	5106	5145	4.38e-11	SMART
EGF_CA	5146	5190	4.49e-8	SMART
EGF_CA	5191	5228	2.38e-12	SMART
EGF_CA	5229	5270	6.8e-8	SMART
EGF_CA	5271	5313	3.51e-10	SMART
EGF_CA	5314	5353	2.78e-13	SMART
EGF	5357	5399	1.44e1	SMART

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000177268

Meta Mutation Damage Score

0.1795

Coding Region Coverage

1x: 99.5%
3x: 98.2%
10x: 92.4%
20x: 72.0%

Validation Efficiency

MGI Phenotype

FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a large extracellular member of the immunoglobulin superfamily. A similar protein in C. elegans forms long, fine tracks at specific extracellular sites that are involved in many processes such as stabilization of the germline syncytium, anchorage of mechanosensory neurons to the epidermis, and organization of hemidesmosomes in the epidermis. Mutations in this gene may be associated with age-related macular degeneration. [provided by RefSeq, Jul 2008]

Allele List at MGI

All alleles(4) : Targeted(3) Gene trapped(1)

Other mutations in this stock

Total: 72 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Abca8b	A	G	11: 109,846,002 (GRCm39)	C811R	possibly damaging	Het
Akap8l	G	A	17: 32,557,416 (GRCm39)	T65I	possibly damaging	Het
Arid4a	T	A	12: 71,069,034 (GRCm39)		probably null	Het
Armc2	C	T	10: 41,842,696 (GRCm39)		probably null	Het
Atp6v1g1	A	G	4: 63,468,258 (GRCm39)	Y87C	probably benign	Het
Cfap54	A	T	10: 92,757,281 (GRCm39)	F273I	possibly damaging	Het
Clasrp	C	A	7: 19,319,165 (GRCm39)		probably benign	Het
Csmd2	T	C	4: 128,451,511 (GRCm39)	F113S	unknown	Het
Cyp4a14	C	A	4: 115,344,498 (GRCm39)	G456W	probably damaging	Het
Cyp4a30b	A	G	4: 115,315,559 (GRCm39)	H260R	possibly damaging	Het
Ddrgk1	T	A	2: 130,506,564 (GRCm39)		probably benign	Het
Dennd2b	A	T	7: 109,156,637 (GRCm39)	Y38N	probably benign	Het
Dhx57	A	T	17: 80,558,805 (GRCm39)	D1051E	probably benign	Het
Eef2	GCCC	GCCCC	10: 81,014,601 (GRCm39)		probably null	Het
Eif4enif1	C	T	11: 3,192,586 (GRCm39)	P805S	probably damaging	Het
Eml5	C	T	12: 98,831,660 (GRCm39)	D433N	probably damaging	Het
Fan1	A	G	7: 64,012,938 (GRCm39)	I668T	probably benign	Het
Frmpd4	A	T	X: 166,260,243 (GRCm39)	D1166E	probably benign	Het
Ftdc1	A	T	16: 58,434,342 (GRCm39)	I125K	probably benign	Het
Gria2	G	A	3: 80,609,799 (GRCm39)	T670I	probably damaging	Het
Grid2ip	C	A	5: 143,343,684 (GRCm39)	Q127K	probably benign	Het
Hdhd2	T	C	18: 77,042,702 (GRCm39)	F44L	probably damaging	Het
Hjurp	GT	GTT	1: 88,194,246 (GRCm39)		probably null	Het
Ift172	C	T	5: 31,415,205 (GRCm39)	V1335I	probably benign	Het
Ighv2-2	G	A	12: 113,552,118 (GRCm39)	T40I	possibly damaging	Het
Kcnk10	T	A	12: 98,401,072 (GRCm39)	R520S	probably benign	Het
Kif1c	A	G	11: 70,614,907 (GRCm39)	E567G	probably damaging	Het
Klf8	A	T	X: 152,165,678 (GRCm39)	E82D	probably damaging	Het
Kpna7	T	C	5: 144,930,745 (GRCm39)	T367A	probably benign	Het
Lpo	A	G	11: 87,707,350 (GRCm39)	I221T	possibly damaging	Het
Lrrn3	T	C	12: 41,502,722 (GRCm39)	I532V	probably benign	Het
Matr3	T	A	18: 35,705,349 (GRCm39)	S91R	probably benign	Het
Mki67	G	A	7: 135,309,878 (GRCm39)	P191L	probably benign	Het
Mlxip	A	G	5: 123,590,730 (GRCm39)	M878V	probably benign	Het
Mpp7	G	A	18: 7,461,678 (GRCm39)	P65L	possibly damaging	Het
Mroh2a	C	A	1: 88,183,287 (GRCm39)	L1292I	probably damaging	Het
Msh2	C	A	17: 87,993,012 (GRCm39)	Q314K	possibly damaging	Het
Mtor	T	A	4: 148,624,487 (GRCm39)	M2089K	probably benign	Het
Myo9b	G	A	8: 71,786,981 (GRCm39)	R721Q	probably benign	Het
Nlrp4b	C	T	7: 10,444,170 (GRCm39)	Q40*	probably null	Het
Nomo1	C	A	7: 45,696,361 (GRCm39)	T293N	probably damaging	Het
Notum	A	G	11: 120,551,022 (GRCm39)	V48A	probably benign	Het
Npas3	C	T	12: 54,114,796 (GRCm39)	R542*	probably null	Het
Or10z1	T	C	1: 174,078,092 (GRCm39)	S134G	probably benign	Het
Or13a17	A	G	7: 140,271,198 (GRCm39)	I127V	possibly damaging	Het
Or13j1	C	A	4: 43,706,458 (GRCm39)	V37L	probably benign	Het
Or5t16	A	T	2: 86,819,192 (GRCm39)	C109*	probably null	Het
Ostc	T	C	3: 130,497,157 (GRCm39)	N80S	probably damaging	Het
Palmd	T	C	3: 116,717,400 (GRCm39)	R366G	possibly damaging	Het
Parp1	A	G	1: 180,401,230 (GRCm39)	D45G	probably damaging	Het
Pcdhga9	T	A	18: 37,870,524 (GRCm39)	Y118N	possibly damaging	Het
Pes1	C	A	11: 3,926,834 (GRCm39)	T372K	probably benign	Het
Pkp4	C	A	2: 59,138,500 (GRCm39)	T250K	probably benign	Het
Plekhg5	T	A	4: 152,191,960 (GRCm39)	C433S	probably benign	Het
Plin2	A	G	4: 86,586,915 (GRCm39)	M1T	probably null	Het
Prdx4	A	G	X: 154,123,460 (GRCm39)	V15A	probably benign	Het
Psmb8	T	C	17: 34,419,144 (GRCm39)	I146T	probably damaging	Het
Psmd13	A	T	7: 140,466,968 (GRCm39)	T116S	probably damaging	Het
Rel	T	C	11: 23,711,129 (GRCm39)	I13V	probably benign	Het
Reln	C	T	5: 22,254,789 (GRCm39)	V527I	possibly damaging	Het
Rnf6	T	C	5: 146,147,215 (GRCm39)	Y601C	probably benign	Het
Rps6kc1	T	C	1: 190,631,766 (GRCm39)	I48M	probably damaging	Het
Sfi1	CCTCTC	CCTCTCTC	11: 3,127,419 (GRCm39)		probably benign	Het
Shoc1	A	C	4: 59,093,850 (GRCm39)	L226R	probably damaging	Het
Slc39a8	T	A	3: 135,592,554 (GRCm39)		probably null	Het
Sppl2c	C	T	11: 104,078,141 (GRCm39)	P314S	probably benign	Het
Tnni3k	C	T	3: 154,644,387 (GRCm39)		probably null	Het
Ugt1a1	AT	A	1: 88,140,093 (GRCm39)		probably null	Het
Vmn2r68	A	C	7: 84,882,834 (GRCm39)	M306R	probably benign	Het
Vmn2r70	T	A	7: 85,208,227 (GRCm39)	Y750F	probably damaging	Het
Vwa7	G	A	17: 35,240,218 (GRCm39)	M395I	probably damaging	Het
Zfp53	A	T	17: 21,728,340 (GRCm39)	E124D	probably benign	Het

Other mutations in Hmcn1

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00417:Hmcn1	APN	1	150,553,029 (GRCm39)	missense	probably benign
IGL00571:Hmcn1	APN	1	150,514,750 (GRCm39)	missense	probably benign	0.05
IGL00726:Hmcn1	APN	1	150,682,117 (GRCm39)	critical splice donor site	probably null
IGL00802:Hmcn1	APN	1	150,540,687 (GRCm39)	missense	probably benign	0.19
IGL00824:Hmcn1	APN	1	150,532,485 (GRCm39)	missense	probably damaging	1.00
IGL00834:Hmcn1	APN	1	150,506,091 (GRCm39)	missense	probably benign	0.00
IGL00843:Hmcn1	APN	1	150,486,464 (GRCm39)	missense	possibly damaging	0.95
IGL00845:Hmcn1	APN	1	150,480,757 (GRCm39)	missense	probably damaging	0.98
IGL00851:Hmcn1	APN	1	150,458,052 (GRCm39)	missense	probably benign	0.02
IGL00909:Hmcn1	APN	1	150,514,620 (GRCm39)	missense	probably benign	0.12
IGL01074:Hmcn1	APN	1	150,502,784 (GRCm39)	missense	possibly damaging	0.82
IGL01112:Hmcn1	APN	1	150,508,303 (GRCm39)	splice site	probably benign
IGL01304:Hmcn1	APN	1	150,498,675 (GRCm39)	missense	probably damaging	0.99
IGL01307:Hmcn1	APN	1	150,620,752 (GRCm39)	missense	possibly damaging	0.84
IGL01318:Hmcn1	APN	1	150,594,991 (GRCm39)	missense	probably damaging	1.00
IGL01403:Hmcn1	APN	1	150,468,848 (GRCm39)	missense	probably damaging	1.00
IGL01417:Hmcn1	APN	1	150,734,990 (GRCm39)	missense	probably damaging	1.00
IGL01503:Hmcn1	APN	1	150,480,823 (GRCm39)	missense	probably benign	0.38
IGL01509:Hmcn1	APN	1	150,485,382 (GRCm39)	missense	probably damaging	1.00
IGL01550:Hmcn1	APN	1	150,474,148 (GRCm39)	missense	probably damaging	1.00
IGL01601:Hmcn1	APN	1	150,503,164 (GRCm39)	missense	probably benign	0.01
IGL01617:Hmcn1	APN	1	150,547,783 (GRCm39)	missense	probably benign	0.05
IGL01636:Hmcn1	APN	1	150,455,984 (GRCm39)	missense	probably damaging	1.00
IGL01662:Hmcn1	APN	1	150,613,050 (GRCm39)	missense	possibly damaging	0.46
IGL01693:Hmcn1	APN	1	150,459,031 (GRCm39)	missense	probably damaging	1.00
IGL01723:Hmcn1	APN	1	150,620,711 (GRCm39)	missense	probably benign	0.01
IGL01776:Hmcn1	APN	1	150,547,789 (GRCm39)	missense	possibly damaging	0.70
IGL01783:Hmcn1	APN	1	150,491,051 (GRCm39)	missense	possibly damaging	0.60
IGL01789:Hmcn1	APN	1	150,566,352 (GRCm39)	missense	probably damaging	1.00
IGL01900:Hmcn1	APN	1	150,618,011 (GRCm39)	splice site	probably benign
IGL01906:Hmcn1	APN	1	150,543,638 (GRCm39)	missense	probably benign	0.01
IGL01947:Hmcn1	APN	1	150,608,643 (GRCm39)	missense	possibly damaging	0.93
IGL01958:Hmcn1	APN	1	150,479,622 (GRCm39)	missense	probably benign	0.01
IGL02002:Hmcn1	APN	1	150,491,049 (GRCm39)	missense	probably damaging	1.00
IGL02058:Hmcn1	APN	1	150,579,932 (GRCm39)	missense	probably benign	0.02
IGL02115:Hmcn1	APN	1	150,506,479 (GRCm39)	missense	probably damaging	1.00
IGL02127:Hmcn1	APN	1	150,598,358 (GRCm39)	missense	probably benign
IGL02155:Hmcn1	APN	1	150,439,349 (GRCm39)	missense	probably damaging	1.00
IGL02222:Hmcn1	APN	1	150,682,152 (GRCm39)	missense	probably benign	0.05
IGL02293:Hmcn1	APN	1	150,540,666 (GRCm39)	missense	probably damaging	0.97
IGL02398:Hmcn1	APN	1	150,678,648 (GRCm39)	missense	possibly damaging	0.78
IGL02420:Hmcn1	APN	1	150,598,175 (GRCm39)	missense	probably damaging	1.00
IGL02553:Hmcn1	APN	1	150,868,774 (GRCm39)	missense	probably benign	0.12
IGL02561:Hmcn1	APN	1	150,685,477 (GRCm39)	missense	probably benign	0.32
IGL02569:Hmcn1	APN	1	150,573,244 (GRCm39)	missense	probably benign	0.01
IGL02607:Hmcn1	APN	1	150,620,746 (GRCm39)	missense	possibly damaging	0.88
IGL02676:Hmcn1	APN	1	150,494,760 (GRCm39)	missense	probably benign	0.01
IGL02725:Hmcn1	APN	1	150,480,654 (GRCm39)	missense	possibly damaging	0.92
IGL02726:Hmcn1	APN	1	150,532,445 (GRCm39)	nonsense	probably null
IGL02735:Hmcn1	APN	1	150,522,583 (GRCm39)	missense	probably benign	0.02
IGL02737:Hmcn1	APN	1	150,439,579 (GRCm39)	missense	probably damaging	1.00
IGL02892:Hmcn1	APN	1	150,551,725 (GRCm39)	critical splice donor site	probably null
IGL02927:Hmcn1	APN	1	150,453,029 (GRCm39)	missense	probably damaging	1.00
IGL02931:Hmcn1	APN	1	150,532,958 (GRCm39)	missense	probably benign	0.37
IGL02936:Hmcn1	APN	1	150,573,273 (GRCm39)	missense	probably damaging	0.98
IGL02985:Hmcn1	APN	1	150,547,668 (GRCm39)	missense	probably damaging	1.00
IGL03027:Hmcn1	APN	1	150,684,290 (GRCm39)	missense	probably benign
IGL03195:Hmcn1	APN	1	150,678,660 (GRCm39)	missense	probably benign	0.06
IGL03217:Hmcn1	APN	1	150,619,418 (GRCm39)	missense	possibly damaging	0.58
IGL03232:Hmcn1	APN	1	150,646,103 (GRCm39)	splice site	probably benign
IGL03268:Hmcn1	APN	1	150,648,261 (GRCm39)	missense	probably damaging	1.00
IGL03271:Hmcn1	APN	1	150,474,175 (GRCm39)	missense	possibly damaging	0.92
IGL03304:Hmcn1	APN	1	150,505,982 (GRCm39)	missense	probably damaging	0.97
IGL03329:Hmcn1	APN	1	150,608,661 (GRCm39)	missense	probably damaging	1.00
IGL03339:Hmcn1	APN	1	150,577,720 (GRCm39)	missense	probably benign	0.04
IGL03368:Hmcn1	APN	1	150,539,623 (GRCm39)	missense	probably damaging	1.00
Backbone	UTSW	1	150,498,745 (GRCm39)	missense	probably benign	0.09
Cambrian	UTSW	1	150,608,597 (GRCm39)	missense	probably damaging	1.00
chordate	UTSW	1	150,462,766 (GRCm39)	missense	probably benign	0.00
Justamere	UTSW	1	150,464,008 (GRCm39)	missense	probably damaging	1.00
Lancelet	UTSW	1	150,551,291 (GRCm39)	missense	probably benign	0.00
notochord	UTSW	1	150,646,044 (GRCm39)	missense	probably benign	0.00
wippoorwill	UTSW	1	150,608,697 (GRCm39)	missense	probably damaging	1.00
BB004:Hmcn1	UTSW	1	150,485,526 (GRCm39)	missense	probably damaging	1.00
BB014:Hmcn1	UTSW	1	150,485,526 (GRCm39)	missense	probably damaging	1.00
IGL02991:Hmcn1	UTSW	1	150,614,409 (GRCm39)	missense	possibly damaging	0.56
P0017:Hmcn1	UTSW	1	150,596,440 (GRCm39)	missense	possibly damaging	0.49
PIT1430001:Hmcn1	UTSW	1	150,684,488 (GRCm39)	missense	probably benign	0.00
PIT4514001:Hmcn1	UTSW	1	150,545,238 (GRCm39)	missense	possibly damaging	0.93
R0006:Hmcn1	UTSW	1	150,684,427 (GRCm39)	missense	probably damaging	0.99
R0018:Hmcn1	UTSW	1	150,528,302 (GRCm39)	missense	probably benign	0.16
R0052:Hmcn1	UTSW	1	150,553,157 (GRCm39)	missense	probably damaging	1.00
R0107:Hmcn1	UTSW	1	150,462,766 (GRCm39)	missense	probably benign	0.00
R0115:Hmcn1	UTSW	1	150,684,398 (GRCm39)	missense	possibly damaging	0.88
R0149:Hmcn1	UTSW	1	150,553,075 (GRCm39)	missense	probably benign	0.00
R0152:Hmcn1	UTSW	1	150,539,630 (GRCm39)	missense	probably benign	0.01
R0381:Hmcn1	UTSW	1	150,479,562 (GRCm39)	missense	probably damaging	1.00
R0398:Hmcn1	UTSW	1	150,674,565 (GRCm39)	missense	possibly damaging	0.83
R0414:Hmcn1	UTSW	1	150,591,573 (GRCm39)	missense	possibly damaging	0.72
R0494:Hmcn1	UTSW	1	150,608,543 (GRCm39)	splice site	probably benign
R0503:Hmcn1	UTSW	1	150,735,003 (GRCm39)	missense	probably damaging	1.00
R0504:Hmcn1	UTSW	1	150,752,170 (GRCm39)	splice site	probably benign
R0506:Hmcn1	UTSW	1	150,618,092 (GRCm39)	missense	possibly damaging	0.69
R0554:Hmcn1	UTSW	1	150,594,868 (GRCm39)	missense	probably benign	0.34
R0576:Hmcn1	UTSW	1	150,525,768 (GRCm39)	nonsense	probably null
R0599:Hmcn1	UTSW	1	150,485,552 (GRCm39)	missense	possibly damaging	0.91
R0605:Hmcn1	UTSW	1	150,533,127 (GRCm39)	critical splice donor site	probably null
R0607:Hmcn1	UTSW	1	150,514,651 (GRCm39)	missense	probably benign	0.01
R0620:Hmcn1	UTSW	1	150,469,767 (GRCm39)	missense	probably benign	0.04
R0626:Hmcn1	UTSW	1	150,674,470 (GRCm39)	splice site	probably null
R0699:Hmcn1	UTSW	1	150,695,161 (GRCm39)	missense	probably damaging	1.00
R0765:Hmcn1	UTSW	1	150,684,538 (GRCm39)	missense	probably damaging	1.00
R0782:Hmcn1	UTSW	1	150,629,416 (GRCm39)	missense	possibly damaging	0.82
R0783:Hmcn1	UTSW	1	150,525,824 (GRCm39)	missense	probably damaging	1.00
R0841:Hmcn1	UTSW	1	150,555,358 (GRCm39)	splice site	probably null
R0975:Hmcn1	UTSW	1	150,453,128 (GRCm39)	missense	probably benign	0.00
R1070:Hmcn1	UTSW	1	150,565,341 (GRCm39)	missense	probably damaging	0.98
R1118:Hmcn1	UTSW	1	150,494,679 (GRCm39)	missense	possibly damaging	0.56
R1119:Hmcn1	UTSW	1	150,494,679 (GRCm39)	missense	possibly damaging	0.56
R1145:Hmcn1	UTSW	1	150,555,358 (GRCm39)	splice site	probably null
R1145:Hmcn1	UTSW	1	150,555,358 (GRCm39)	splice site	probably null
R1233:Hmcn1	UTSW	1	150,624,777 (GRCm39)	missense	probably benign
R1234:Hmcn1	UTSW	1	150,629,405 (GRCm39)	nonsense	probably null
R1291:Hmcn1	UTSW	1	150,623,942 (GRCm39)	missense	probably damaging	1.00
R1334:Hmcn1	UTSW	1	150,462,219 (GRCm39)	missense	possibly damaging	0.73
R1372:Hmcn1	UTSW	1	150,556,466 (GRCm39)	missense	probably benign	0.22
R1424:Hmcn1	UTSW	1	150,522,545 (GRCm39)	missense	probably benign	0.00
R1450:Hmcn1	UTSW	1	150,528,257 (GRCm39)	splice site	probably benign
R1458:Hmcn1	UTSW	1	150,485,451 (GRCm39)	missense	probably damaging	1.00
R1467:Hmcn1	UTSW	1	150,565,341 (GRCm39)	missense	probably damaging	0.98
R1467:Hmcn1	UTSW	1	150,565,341 (GRCm39)	missense	probably damaging	0.98
R1473:Hmcn1	UTSW	1	150,648,303 (GRCm39)	missense	probably benign	0.03
R1517:Hmcn1	UTSW	1	150,545,172 (GRCm39)	missense	probably damaging	1.00
R1527:Hmcn1	UTSW	1	150,649,554 (GRCm39)	missense	probably benign	0.00
R1557:Hmcn1	UTSW	1	150,610,283 (GRCm39)	missense	possibly damaging	0.86
R1576:Hmcn1	UTSW	1	150,532,992 (GRCm39)	missense	possibly damaging	0.77
R1617:Hmcn1	UTSW	1	150,620,778 (GRCm39)	missense	probably damaging	0.98
R1635:Hmcn1	UTSW	1	150,545,309 (GRCm39)	missense	probably benign	0.00
R1655:Hmcn1	UTSW	1	150,506,084 (GRCm39)	missense	probably benign	0.03
R1698:Hmcn1	UTSW	1	150,441,120 (GRCm39)	nonsense	probably null
R1710:Hmcn1	UTSW	1	150,551,735 (GRCm39)	missense	probably damaging	1.00
R1717:Hmcn1	UTSW	1	150,734,937 (GRCm39)	missense	probably damaging	1.00
R1753:Hmcn1	UTSW	1	150,462,219 (GRCm39)	missense	possibly damaging	0.73
R1756:Hmcn1	UTSW	1	150,474,781 (GRCm39)	missense	probably damaging	1.00
R1772:Hmcn1	UTSW	1	150,439,319 (GRCm39)	missense	probably damaging	0.99
R1793:Hmcn1	UTSW	1	150,624,834 (GRCm39)	missense	probably benign	0.01
R1794:Hmcn1	UTSW	1	150,502,903 (GRCm39)	missense	probably damaging	0.98
R1794:Hmcn1	UTSW	1	150,474,036 (GRCm39)	missense	probably benign	0.00
R1856:Hmcn1	UTSW	1	150,597,415 (GRCm39)	missense	probably benign	0.02
R1859:Hmcn1	UTSW	1	150,532,944 (GRCm39)	missense	probably damaging	1.00
R1862:Hmcn1	UTSW	1	150,514,651 (GRCm39)	missense	probably benign	0.01
R1865:Hmcn1	UTSW	1	150,479,563 (GRCm39)	missense	probably damaging	1.00
R1874:Hmcn1	UTSW	1	150,596,446 (GRCm39)	missense	probably damaging	1.00
R1880:Hmcn1	UTSW	1	150,514,651 (GRCm39)	missense	probably benign	0.01
R1881:Hmcn1	UTSW	1	150,514,651 (GRCm39)	missense	probably benign	0.01
R1886:Hmcn1	UTSW	1	150,453,046 (GRCm39)	missense	probably benign	0.02
R1888:Hmcn1	UTSW	1	150,695,251 (GRCm39)	missense	possibly damaging	0.82
R1888:Hmcn1	UTSW	1	150,695,251 (GRCm39)	missense	possibly damaging	0.82
R1899:Hmcn1	UTSW	1	150,533,202 (GRCm39)	missense	probably damaging	1.00
R1905:Hmcn1	UTSW	1	150,868,606 (GRCm39)	missense	probably damaging	1.00
R1912:Hmcn1	UTSW	1	150,480,633 (GRCm39)	missense	probably benign	0.28
R1959:Hmcn1	UTSW	1	150,525,427 (GRCm39)	missense	probably benign	0.00
R1960:Hmcn1	UTSW	1	150,553,127 (GRCm39)	missense	possibly damaging	0.72
R1960:Hmcn1	UTSW	1	150,551,742 (GRCm39)	missense	probably benign	0.00
R2001:Hmcn1	UTSW	1	150,614,364 (GRCm39)	missense	possibly damaging	0.81
R2011:Hmcn1	UTSW	1	150,553,085 (GRCm39)	missense	probably benign	0.01
R2075:Hmcn1	UTSW	1	150,453,074 (GRCm39)	missense	possibly damaging	0.86
R2136:Hmcn1	UTSW	1	150,509,410 (GRCm39)	missense	probably damaging	1.00
R2192:Hmcn1	UTSW	1	150,591,566 (GRCm39)	missense	probably damaging	0.97
R2267:Hmcn1	UTSW	1	150,474,761 (GRCm39)	missense	probably benign	0.00
R2268:Hmcn1	UTSW	1	150,500,349 (GRCm39)	splice site	probably benign
R2303:Hmcn1	UTSW	1	150,579,977 (GRCm39)	missense	probably damaging	1.00
R2330:Hmcn1	UTSW	1	150,528,429 (GRCm39)	splice site	probably benign
R2338:Hmcn1	UTSW	1	150,498,685 (GRCm39)	missense	possibly damaging	0.89
R2380:Hmcn1	UTSW	1	150,441,135 (GRCm39)	missense	probably benign	0.01
R2405:Hmcn1	UTSW	1	150,736,092 (GRCm39)	missense	probably damaging	1.00
R2443:Hmcn1	UTSW	1	150,474,783 (GRCm39)	missense	probably benign	0.01
R2496:Hmcn1	UTSW	1	150,490,972 (GRCm39)	missense	probably benign	0.01
R2504:Hmcn1	UTSW	1	150,562,618 (GRCm39)	nonsense	probably null
R2519:Hmcn1	UTSW	1	150,649,571 (GRCm39)	nonsense	probably null
R2520:Hmcn1	UTSW	1	150,619,398 (GRCm39)	missense	possibly damaging	0.72
R2679:Hmcn1	UTSW	1	150,528,326 (GRCm39)	missense	possibly damaging	0.67
R2831:Hmcn1	UTSW	1	150,506,403 (GRCm39)	critical splice donor site	probably null
R2847:Hmcn1	UTSW	1	150,439,350 (GRCm39)	nonsense	probably null
R2849:Hmcn1	UTSW	1	150,439,350 (GRCm39)	nonsense	probably null
R2869:Hmcn1	UTSW	1	150,614,467 (GRCm39)	missense	possibly damaging	0.95
R2869:Hmcn1	UTSW	1	150,614,467 (GRCm39)	missense	possibly damaging	0.95
R2871:Hmcn1	UTSW	1	150,614,467 (GRCm39)	missense	possibly damaging	0.95
R2872:Hmcn1	UTSW	1	150,614,467 (GRCm39)	missense	possibly damaging	0.95
R2872:Hmcn1	UTSW	1	150,614,467 (GRCm39)	missense	possibly damaging	0.95
R2873:Hmcn1	UTSW	1	150,614,467 (GRCm39)	missense	possibly damaging	0.95
R2897:Hmcn1	UTSW	1	150,678,624 (GRCm39)	missense	probably damaging	1.00
R2905:Hmcn1	UTSW	1	150,624,786 (GRCm39)	missense	probably damaging	1.00
R3498:Hmcn1	UTSW	1	150,480,853 (GRCm39)	missense	probably damaging	0.98
R3499:Hmcn1	UTSW	1	150,480,853 (GRCm39)	missense	probably damaging	0.98
R3724:Hmcn1	UTSW	1	150,565,269 (GRCm39)	missense	possibly damaging	0.82
R3765:Hmcn1	UTSW	1	150,620,776 (GRCm39)	missense	possibly damaging	0.72
R3778:Hmcn1	UTSW	1	150,678,575 (GRCm39)	missense	possibly damaging	0.95
R3790:Hmcn1	UTSW	1	150,498,745 (GRCm39)	missense	probably benign	0.09
R3796:Hmcn1	UTSW	1	150,462,169 (GRCm39)	missense	probably damaging	1.00
R3811:Hmcn1	UTSW	1	150,525,328 (GRCm39)	critical splice donor site	probably null
R3825:Hmcn1	UTSW	1	150,462,716 (GRCm39)	missense	probably benign	0.28
R3890:Hmcn1	UTSW	1	150,510,946 (GRCm39)	missense	probably damaging	1.00
R3891:Hmcn1	UTSW	1	150,510,946 (GRCm39)	missense	probably damaging	1.00
R3892:Hmcn1	UTSW	1	150,510,946 (GRCm39)	missense	probably damaging	1.00
R3918:Hmcn1	UTSW	1	150,566,361 (GRCm39)	missense	probably benign	0.00
R3964:Hmcn1	UTSW	1	150,449,320 (GRCm39)	missense	probably benign	0.00
R4005:Hmcn1	UTSW	1	150,598,204 (GRCm39)	missense	possibly damaging	0.88
R4026:Hmcn1	UTSW	1	150,598,120 (GRCm39)	missense	probably benign	0.03
R4037:Hmcn1	UTSW	1	150,648,253 (GRCm39)	missense	probably benign	0.00
R4088:Hmcn1	UTSW	1	150,578,967 (GRCm39)	missense	possibly damaging	0.58
R4096:Hmcn1	UTSW	1	150,534,259 (GRCm39)	missense	probably benign	0.20
R4169:Hmcn1	UTSW	1	150,471,750 (GRCm39)	splice site	probably null
R4441:Hmcn1	UTSW	1	150,533,210 (GRCm39)	missense	probably null
R4493:Hmcn1	UTSW	1	150,577,650 (GRCm39)	missense	probably damaging	1.00
R4501:Hmcn1	UTSW	1	150,509,417 (GRCm39)	missense	probably damaging	1.00
R4535:Hmcn1	UTSW	1	150,439,531 (GRCm39)	missense	probably damaging	0.99
R4576:Hmcn1	UTSW	1	150,610,238 (GRCm39)	missense	probably benign
R4601:Hmcn1	UTSW	1	150,614,396 (GRCm39)	missense	probably damaging	0.99
R4627:Hmcn1	UTSW	1	150,471,645 (GRCm39)	missense	probably benign	0.11
R4647:Hmcn1	UTSW	1	150,551,262 (GRCm39)	critical splice donor site	probably null
R4657:Hmcn1	UTSW	1	150,500,301 (GRCm39)	missense	probably damaging	1.00
R4717:Hmcn1	UTSW	1	150,494,816 (GRCm39)	missense	probably benign	0.00
R4721:Hmcn1	UTSW	1	150,648,322 (GRCm39)	splice site	probably null
R4724:Hmcn1	UTSW	1	150,570,584 (GRCm39)	splice site	probably null
R4737:Hmcn1	UTSW	1	150,565,346 (GRCm39)	missense	possibly damaging	0.90
R4744:Hmcn1	UTSW	1	150,453,363 (GRCm39)	missense	probably damaging	1.00
R4795:Hmcn1	UTSW	1	150,629,362 (GRCm39)	missense	probably benign	0.00
R4796:Hmcn1	UTSW	1	150,629,362 (GRCm39)	missense	probably benign	0.00
R4871:Hmcn1	UTSW	1	150,468,836 (GRCm39)	missense	probably benign	0.02
R4895:Hmcn1	UTSW	1	150,553,130 (GRCm39)	missense	probably benign	0.00
R4934:Hmcn1	UTSW	1	150,598,286 (GRCm39)	missense	probably damaging	1.00
R4953:Hmcn1	UTSW	1	150,752,111 (GRCm39)	intron	probably benign
R4968:Hmcn1	UTSW	1	150,533,221 (GRCm39)	missense	possibly damaging	0.67
R4974:Hmcn1	UTSW	1	150,695,200 (GRCm39)	missense	probably benign	0.01
R5024:Hmcn1	UTSW	1	150,556,439 (GRCm39)	missense	possibly damaging	0.65
R5031:Hmcn1	UTSW	1	150,464,008 (GRCm39)	missense	probably damaging	1.00
R5093:Hmcn1	UTSW	1	150,613,007 (GRCm39)	missense	probably benign	0.14
R5096:Hmcn1	UTSW	1	150,486,420 (GRCm39)	missense	probably damaging	1.00
R5185:Hmcn1	UTSW	1	150,532,492 (GRCm39)	missense	probably benign	0.03
R5228:Hmcn1	UTSW	1	150,522,452 (GRCm39)	missense	probably benign	0.00
R5260:Hmcn1	UTSW	1	150,471,612 (GRCm39)	missense	possibly damaging	0.65
R5264:Hmcn1	UTSW	1	150,555,265 (GRCm39)	missense	probably benign	0.01
R5282:Hmcn1	UTSW	1	150,458,047 (GRCm39)	missense	probably damaging	1.00
R5334:Hmcn1	UTSW	1	150,631,123 (GRCm39)	missense	probably damaging	0.99
R5346:Hmcn1	UTSW	1	150,498,995 (GRCm39)	missense	probably damaging	1.00
R5423:Hmcn1	UTSW	1	150,577,723 (GRCm39)	missense	probably damaging	1.00
R5484:Hmcn1	UTSW	1	150,551,291 (GRCm39)	missense	probably benign	0.00
R5491:Hmcn1	UTSW	1	150,485,576 (GRCm39)	splice site	probably null
R5531:Hmcn1	UTSW	1	150,619,539 (GRCm39)	missense	probably damaging	1.00
R5536:Hmcn1	UTSW	1	150,631,042 (GRCm39)	missense	probably benign	0.01
R5547:Hmcn1	UTSW	1	150,613,257 (GRCm39)	missense	possibly damaging	0.64
R5580:Hmcn1	UTSW	1	150,453,290 (GRCm39)	missense	probably benign	0.43
R5626:Hmcn1	UTSW	1	150,532,318 (GRCm39)	missense	probably damaging	1.00
R5657:Hmcn1	UTSW	1	150,534,313 (GRCm39)	missense	probably benign	0.02
R5677:Hmcn1	UTSW	1	150,485,529 (GRCm39)	missense	probably benign	0.00
R5718:Hmcn1	UTSW	1	150,566,351 (GRCm39)	nonsense	probably null
R5718:Hmcn1	UTSW	1	150,485,417 (GRCm39)	missense	probably damaging	1.00
R5723:Hmcn1	UTSW	1	150,570,600 (GRCm39)	missense	possibly damaging	0.95
R5739:Hmcn1	UTSW	1	150,634,225 (GRCm39)	splice site	probably null
R5739:Hmcn1	UTSW	1	150,684,448 (GRCm39)	missense	probably benign	0.45
R5751:Hmcn1	UTSW	1	150,449,305 (GRCm39)	missense	probably damaging	1.00
R5772:Hmcn1	UTSW	1	150,570,629 (GRCm39)	missense	possibly damaging	0.47
R5804:Hmcn1	UTSW	1	150,550,098 (GRCm39)	nonsense	probably null
R5809:Hmcn1	UTSW	1	150,525,358 (GRCm39)	missense	probably damaging	1.00
R5817:Hmcn1	UTSW	1	150,613,275 (GRCm39)	missense	possibly damaging	0.77
R5824:Hmcn1	UTSW	1	150,868,774 (GRCm39)	missense	probably benign	0.12
R5881:Hmcn1	UTSW	1	150,506,078 (GRCm39)	missense	probably damaging	0.99
R5928:Hmcn1	UTSW	1	150,474,648 (GRCm39)	missense	possibly damaging	0.64
R5929:Hmcn1	UTSW	1	150,453,047 (GRCm39)	nonsense	probably null
R5940:Hmcn1	UTSW	1	150,532,973 (GRCm39)	missense	probably benign	0.41
R5973:Hmcn1	UTSW	1	150,439,568 (GRCm39)	missense	probably damaging	1.00
R5997:Hmcn1	UTSW	1	150,579,924 (GRCm39)	missense	possibly damaging	0.74
R6027:Hmcn1	UTSW	1	150,678,646 (GRCm39)	missense	possibly damaging	0.79
R6029:Hmcn1	UTSW	1	150,508,188 (GRCm39)	missense	probably benign	0.13
R6056:Hmcn1	UTSW	1	150,539,660 (GRCm39)	missense	probably damaging	1.00
R6065:Hmcn1	UTSW	1	150,646,081 (GRCm39)	missense	probably benign	0.06
R6083:Hmcn1	UTSW	1	150,631,045 (GRCm39)	missense	probably damaging	1.00
R6083:Hmcn1	UTSW	1	150,631,044 (GRCm39)	missense	probably damaging	1.00
R6108:Hmcn1	UTSW	1	150,506,978 (GRCm39)	missense	possibly damaging	0.95
R6112:Hmcn1	UTSW	1	150,494,687 (GRCm39)	missense	probably damaging	1.00
R6140:Hmcn1	UTSW	1	150,608,597 (GRCm39)	missense	probably damaging	1.00
R6144:Hmcn1	UTSW	1	150,598,175 (GRCm39)	missense	probably damaging	1.00
R6152:Hmcn1	UTSW	1	150,441,176 (GRCm39)	missense	probably damaging	1.00
R6174:Hmcn1	UTSW	1	150,522,535 (GRCm39)	missense	probably benign	0.06
R6185:Hmcn1	UTSW	1	150,491,189 (GRCm39)	splice site	probably null
R6187:Hmcn1	UTSW	1	150,506,479 (GRCm39)	missense	probably damaging	1.00
R6276:Hmcn1	UTSW	1	150,614,432 (GRCm39)	missense	possibly damaging	0.69
R6278:Hmcn1	UTSW	1	150,573,170 (GRCm39)	critical splice donor site	probably null
R6427:Hmcn1	UTSW	1	150,573,227 (GRCm39)	missense	possibly damaging	0.85
R6431:Hmcn1	UTSW	1	150,620,711 (GRCm39)	missense	probably benign	0.01
R6441:Hmcn1	UTSW	1	150,578,967 (GRCm39)	missense	possibly damaging	0.58
R6451:Hmcn1	UTSW	1	150,868,670 (GRCm39)	missense	probably damaging	1.00
R6478:Hmcn1	UTSW	1	150,540,535 (GRCm39)	missense	probably damaging	1.00
R6479:Hmcn1	UTSW	1	150,553,053 (GRCm39)	nonsense	probably null
R6490:Hmcn1	UTSW	1	150,459,029 (GRCm39)	missense	probably benign	0.00
R6525:Hmcn1	UTSW	1	150,573,317 (GRCm39)	missense	probably damaging	1.00
R6571:Hmcn1	UTSW	1	150,491,189 (GRCm39)	splice site	probably null
R6612:Hmcn1	UTSW	1	150,470,869 (GRCm39)	critical splice donor site	probably null
R6616:Hmcn1	UTSW	1	150,599,008 (GRCm39)	critical splice donor site	probably null
R6617:Hmcn1	UTSW	1	150,619,547 (GRCm39)	missense	probably benign	0.01
R6623:Hmcn1	UTSW	1	150,634,057 (GRCm39)	missense	probably benign
R6687:Hmcn1	UTSW	1	150,620,784 (GRCm39)	missense	probably benign	0.30
R6714:Hmcn1	UTSW	1	150,579,926 (GRCm39)	missense	probably damaging	0.97
R6751:Hmcn1	UTSW	1	150,610,269 (GRCm39)	missense	probably damaging	0.98
R6831:Hmcn1	UTSW	1	150,646,044 (GRCm39)	missense	probably benign	0.00
R6971:Hmcn1	UTSW	1	150,868,802 (GRCm39)	start codon destroyed	probably benign	0.00
R7048:Hmcn1	UTSW	1	150,475,404 (GRCm39)	critical splice acceptor site	probably null
R7058:Hmcn1	UTSW	1	150,649,641 (GRCm39)	missense	probably benign	0.43
R7071:Hmcn1	UTSW	1	150,479,853 (GRCm39)	missense	probably damaging	1.00
R7078:Hmcn1	UTSW	1	150,736,118 (GRCm39)	missense	probably damaging	1.00
R7092:Hmcn1	UTSW	1	150,479,997 (GRCm39)	missense	probably damaging	1.00
R7120:Hmcn1	UTSW	1	150,576,292 (GRCm39)	missense	probably damaging	0.98
R7129:Hmcn1	UTSW	1	150,452,961 (GRCm39)	splice site	probably null
R7144:Hmcn1	UTSW	1	150,539,624 (GRCm39)	missense	probably damaging	1.00
R7148:Hmcn1	UTSW	1	150,562,605 (GRCm39)	missense	probably benign	0.00
R7162:Hmcn1	UTSW	1	150,624,744 (GRCm39)	missense	probably benign	0.18
R7172:Hmcn1	UTSW	1	150,629,450 (GRCm39)	missense	possibly damaging	0.92
R7193:Hmcn1	UTSW	1	150,525,331 (GRCm39)	missense	probably null	1.00
R7231:Hmcn1	UTSW	1	150,514,627 (GRCm39)	missense	probably benign	0.00
R7237:Hmcn1	UTSW	1	150,598,394 (GRCm39)	missense	probably damaging	0.98
R7258:Hmcn1	UTSW	1	150,591,574 (GRCm39)	missense	probably benign	0.12
R7286:Hmcn1	UTSW	1	150,458,088 (GRCm39)	missense	probably damaging	0.98
R7289:Hmcn1	UTSW	1	150,559,466 (GRCm39)	missense	possibly damaging	0.52
R7292:Hmcn1	UTSW	1	150,608,880 (GRCm39)	splice site	probably null
R7316:Hmcn1	UTSW	1	150,608,697 (GRCm39)	missense	probably damaging	1.00
R7327:Hmcn1	UTSW	1	150,479,565 (GRCm39)	missense	probably benign	0.01
R7328:Hmcn1	UTSW	1	150,514,617 (GRCm39)	missense	possibly damaging	0.95
R7346:Hmcn1	UTSW	1	150,559,496 (GRCm39)	missense	probably damaging	1.00
R7351:Hmcn1	UTSW	1	150,543,640 (GRCm39)	missense	probably damaging	0.98
R7354:Hmcn1	UTSW	1	150,682,196 (GRCm39)	nonsense	probably null
R7360:Hmcn1	UTSW	1	150,494,597 (GRCm39)	missense	probably damaging	1.00
R7396:Hmcn1	UTSW	1	150,439,382 (GRCm39)	missense	possibly damaging	0.83
R7398:Hmcn1	UTSW	1	150,522,421 (GRCm39)	missense	probably benign	0.00
R7400:Hmcn1	UTSW	1	150,550,181 (GRCm39)	missense	probably damaging	1.00
R7404:Hmcn1	UTSW	1	150,596,510 (GRCm39)	missense	probably benign	0.00
R7424:Hmcn1	UTSW	1	150,506,017 (GRCm39)	nonsense	probably null
R7454:Hmcn1	UTSW	1	150,439,355 (GRCm39)	missense	probably damaging	1.00
R7476:Hmcn1	UTSW	1	150,456,018 (GRCm39)	missense	probably damaging	0.99
R7480:Hmcn1	UTSW	1	150,552,985 (GRCm39)	critical splice donor site	probably null
R7516:Hmcn1	UTSW	1	150,498,718 (GRCm39)	missense	probably benign	0.35
R7526:Hmcn1	UTSW	1	150,532,324 (GRCm39)	missense	probably damaging	1.00
R7531:Hmcn1	UTSW	1	150,562,531 (GRCm39)	missense	probably benign	0.06
R7555:Hmcn1	UTSW	1	150,480,625 (GRCm39)	missense	probably benign	0.40
R7564:Hmcn1	UTSW	1	150,531,586 (GRCm39)	missense	probably benign
R7588:Hmcn1	UTSW	1	150,532,885 (GRCm39)	missense	possibly damaging	0.90
R7719:Hmcn1	UTSW	1	150,441,080 (GRCm39)	missense	possibly damaging	0.95
R7720:Hmcn1	UTSW	1	150,522,460 (GRCm39)	missense	probably benign	0.00
R7722:Hmcn1	UTSW	1	150,543,631 (GRCm39)	missense	probably damaging	0.98
R7761:Hmcn1	UTSW	1	150,598,196 (GRCm39)	missense	possibly damaging	0.70
R7787:Hmcn1	UTSW	1	150,632,343 (GRCm39)	missense	probably damaging	1.00
R7803:Hmcn1	UTSW	1	150,646,030 (GRCm39)	missense	probably benign	0.32
R7862:Hmcn1	UTSW	1	150,682,172 (GRCm39)	missense	probably damaging	0.96
R7876:Hmcn1	UTSW	1	150,620,722 (GRCm39)	missense	probably benign	0.03
R7886:Hmcn1	UTSW	1	150,533,221 (GRCm39)	missense	possibly damaging	0.94
R7891:Hmcn1	UTSW	1	150,468,940 (GRCm39)	missense	probably damaging	1.00
R7892:Hmcn1	UTSW	1	150,540,643 (GRCm39)	missense	probably benign	0.00
R7927:Hmcn1	UTSW	1	150,485,526 (GRCm39)	missense	probably damaging	1.00
R7941:Hmcn1	UTSW	1	150,525,835 (GRCm39)	missense	possibly damaging	0.95
R7960:Hmcn1	UTSW	1	150,531,606 (GRCm39)	missense	probably damaging	1.00
R8001:Hmcn1	UTSW	1	150,540,629 (GRCm39)	nonsense	probably null
R8015:Hmcn1	UTSW	1	150,474,062 (GRCm39)	missense	possibly damaging	0.83
R8070:Hmcn1	UTSW	1	150,525,743 (GRCm39)	nonsense	probably null
R8072:Hmcn1	UTSW	1	150,532,256 (GRCm39)	missense	possibly damaging	0.62
R8113:Hmcn1	UTSW	1	150,624,841 (GRCm39)	missense	possibly damaging	0.50
R8143:Hmcn1	UTSW	1	150,734,957 (GRCm39)	missense	probably benign	0.03
R8145:Hmcn1	UTSW	1	150,629,411 (GRCm39)	missense	probably benign	0.33
R8155:Hmcn1	UTSW	1	150,480,705 (GRCm39)	missense	probably damaging	1.00
R8165:Hmcn1	UTSW	1	150,522,409 (GRCm39)	missense	probably benign	0.09
R8179:Hmcn1	UTSW	1	150,598,265 (GRCm39)	missense	probably benign	0.19
R8193:Hmcn1	UTSW	1	150,453,228 (GRCm39)	nonsense	probably null
R8234:Hmcn1	UTSW	1	150,469,761 (GRCm39)	missense	possibly damaging	0.83
R8249:Hmcn1	UTSW	1	150,695,117 (GRCm39)	missense	probably benign	0.24
R8267:Hmcn1	UTSW	1	150,735,005 (GRCm39)	missense	probably damaging	1.00
R8312:Hmcn1	UTSW	1	150,614,515 (GRCm39)	missense	probably damaging	0.99
R8338:Hmcn1	UTSW	1	150,614,485 (GRCm39)	missense	probably benign	0.35
R8354:Hmcn1	UTSW	1	150,634,142 (GRCm39)	missense	possibly damaging	0.79
R8440:Hmcn1	UTSW	1	150,570,671 (GRCm39)	missense	probably damaging	1.00
R8473:Hmcn1	UTSW	1	150,479,551 (GRCm39)	missense	possibly damaging	0.64
R8497:Hmcn1	UTSW	1	150,455,990 (GRCm39)	missense	probably benign	0.01
R8509:Hmcn1	UTSW	1	150,449,302 (GRCm39)	nonsense	probably null
R8559:Hmcn1	UTSW	1	150,551,789 (GRCm39)	missense	probably benign	0.25
R8701:Hmcn1	UTSW	1	150,631,008 (GRCm39)	missense	probably benign	0.00
R8755:Hmcn1	UTSW	1	150,509,371 (GRCm39)	missense	probably benign	0.19
R8765:Hmcn1	UTSW	1	150,556,413 (GRCm39)	missense	probably damaging	0.98
R8782:Hmcn1	UTSW	1	150,540,636 (GRCm39)	missense	probably benign	0.08
R8794:Hmcn1	UTSW	1	150,591,469 (GRCm39)	missense	probably benign	0.00
R8803:Hmcn1	UTSW	1	150,610,248 (GRCm39)	missense	probably damaging	1.00
R8808:Hmcn1	UTSW	1	150,531,570 (GRCm39)	missense	possibly damaging	0.64
R8853:Hmcn1	UTSW	1	150,547,726 (GRCm39)	missense	probably damaging	1.00
R8877:Hmcn1	UTSW	1	150,514,659 (GRCm39)	missense	probably benign	0.00
R8881:Hmcn1	UTSW	1	150,525,723 (GRCm39)	missense	probably damaging	1.00
R8916:Hmcn1	UTSW	1	150,649,530 (GRCm39)	missense	probably damaging	1.00
R9008:Hmcn1	UTSW	1	150,630,795 (GRCm39)	intron	probably benign
R9030:Hmcn1	UTSW	1	150,692,870 (GRCm39)	missense	probably benign	0.00
R9072:Hmcn1	UTSW	1	150,565,320 (GRCm39)	missense	probably benign	0.04
R9090:Hmcn1	UTSW	1	150,632,309 (GRCm39)	missense	probably damaging	1.00
R9096:Hmcn1	UTSW	1	150,532,869 (GRCm39)	missense	probably benign	0.04
R9102:Hmcn1	UTSW	1	150,573,331 (GRCm39)	missense	probably benign	0.01
R9146:Hmcn1	UTSW	1	150,474,141 (GRCm39)	missense	probably benign	0.02
R9157:Hmcn1	UTSW	1	150,522,343 (GRCm39)	missense	probably benign	0.06
R9169:Hmcn1	UTSW	1	150,506,092 (GRCm39)	missense	probably damaging	0.99
R9182:Hmcn1	UTSW	1	150,488,405 (GRCm39)	missense	probably damaging	1.00
R9182:Hmcn1	UTSW	1	150,500,337 (GRCm39)	nonsense	probably null
R9204:Hmcn1	UTSW	1	150,610,262 (GRCm39)	missense	probably benign	0.40
R9219:Hmcn1	UTSW	1	150,594,844 (GRCm39)	critical splice donor site	probably null
R9267:Hmcn1	UTSW	1	150,473,740 (GRCm39)	missense	probably benign	0.26
R9271:Hmcn1	UTSW	1	150,632,309 (GRCm39)	missense	probably damaging	1.00
R9274:Hmcn1	UTSW	1	150,506,046 (GRCm39)	missense	probably benign	0.01
R9313:Hmcn1	UTSW	1	150,522,343 (GRCm39)	missense	probably benign	0.06
R9414:Hmcn1	UTSW	1	150,545,187 (GRCm39)	missense	probably damaging	1.00
R9456:Hmcn1	UTSW	1	150,506,053 (GRCm39)	nonsense	probably null
R9464:Hmcn1	UTSW	1	150,599,248 (GRCm39)	missense	possibly damaging	0.80
R9474:Hmcn1	UTSW	1	150,506,471 (GRCm39)	missense	probably damaging	1.00
R9476:Hmcn1	UTSW	1	150,462,127 (GRCm39)	missense	probably benign	0.00
R9482:Hmcn1	UTSW	1	150,610,281 (GRCm39)	missense	probably benign	0.06
R9496:Hmcn1	UTSW	1	150,579,971 (GRCm39)	missense	probably benign	0.00
R9501:Hmcn1	UTSW	1	150,470,990 (GRCm39)	missense	possibly damaging	0.67
R9510:Hmcn1	UTSW	1	150,462,127 (GRCm39)	missense	probably benign	0.00
R9529:Hmcn1	UTSW	1	150,545,175 (GRCm39)	missense	probably damaging	1.00
R9566:Hmcn1	UTSW	1	150,498,660 (GRCm39)	missense	probably benign	0.00
R9608:Hmcn1	UTSW	1	150,475,303 (GRCm39)	missense	probably damaging	1.00
R9609:Hmcn1	UTSW	1	150,555,346 (GRCm39)	missense	probably damaging	0.96
R9616:Hmcn1	UTSW	1	150,684,473 (GRCm39)	missense	probably benign	0.16
R9627:Hmcn1	UTSW	1	150,506,054 (GRCm39)	missense	probably damaging	1.00
R9668:Hmcn1	UTSW	1	150,619,492 (GRCm39)	missense	probably benign	0.02
R9686:Hmcn1	UTSW	1	150,613,356 (GRCm39)	missense	probably damaging	0.99
R9717:Hmcn1	UTSW	1	150,485,378 (GRCm39)	missense	probably damaging	1.00
R9727:Hmcn1	UTSW	1	150,674,566 (GRCm39)	missense	probably benign	0.06
R9744:Hmcn1	UTSW	1	150,623,941 (GRCm39)	missense	probably damaging	1.00
R9749:Hmcn1	UTSW	1	150,632,339 (GRCm39)	missense	possibly damaging	0.94
R9761:Hmcn1	UTSW	1	150,868,625 (GRCm39)	missense	probably damaging	0.98
R9783:Hmcn1	UTSW	1	150,598,380 (GRCm39)	missense	probably benign	0.16
R9788:Hmcn1	UTSW	1	150,528,333 (GRCm39)	missense	probably benign	0.00
R9792:Hmcn1	UTSW	1	150,608,689 (GRCm39)	missense	possibly damaging	0.94
R9793:Hmcn1	UTSW	1	150,608,689 (GRCm39)	missense	possibly damaging	0.94
R9795:Hmcn1	UTSW	1	150,608,689 (GRCm39)	missense	possibly damaging	0.94
R9802:Hmcn1	UTSW	1	150,684,391 (GRCm39)	missense	probably benign	0.07
RF003:Hmcn1	UTSW	1	150,500,312 (GRCm39)	missense	probably damaging	1.00
RF005:Hmcn1	UTSW	1	150,510,897 (GRCm39)	nonsense	probably null
X0022:Hmcn1	UTSW	1	150,576,281 (GRCm39)	missense	probably benign	0.04
X0027:Hmcn1	UTSW	1	150,736,127 (GRCm39)	missense	probably damaging	1.00
X0028:Hmcn1	UTSW	1	150,539,652 (GRCm39)	missense	probably damaging	1.00
Z1088:Hmcn1	UTSW	1	150,524,688 (GRCm39)	missense	probably damaging	1.00
Z1176:Hmcn1	UTSW	1	150,539,668 (GRCm39)	missense	probably benign	0.12
Z1176:Hmcn1	UTSW	1	150,531,672 (GRCm39)	missense	possibly damaging	0.65
Z1176:Hmcn1	UTSW	1	150,462,196 (GRCm39)	missense	probably null	0.92

Predicted Primers

PCR Primer
(F):5'- AAGTGCAAACCAATTTCCTACCTTC -3'
(R):5'- GGCCTCAGGATACACATTAGAG -3'

Sequencing Primer
(F):5'- AGAAACAGTCATACTTTTAGCGATG -3'
(R):5'- CTCAGGATACACATTAGAGTCATAGC -3'

Posted On

2014-12-04