Incidental Mutation 'R2959:Gm5407'
| ID |
255862 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Gm5407
|
| Ensembl Gene |
ENSMUSG00000058176 |
| Gene Name |
predicted gene 5407 |
| Synonyms |
|
| Accession Numbers |
|
| Essential gene? |
Possibly non essential
(E-score: 0.267)
|
| Stock # |
R2959 (G1)
|
| Quality Score |
225 |
|
Status
|
Not validated
|
| Chromosome |
16 |
| Chromosomal Location |
49117014-49118261 bp(-) (GRCm39) |
| Type of Mutation |
exon |
| DNA Base Change (assembly) |
A to T
at 49117326 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000079520
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000080694]
|
| AlphaFold |
no structure available at present |
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000080694
|
| SMART Domains |
Protein: ENSMUSP00000079520
Gene: ENSMUSG00000058176
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:Peptidase_C48
|
67 |
247 |
6.5e-43 |
PFAM |
|
| Coding Region Coverage |
- 1x: 99.2%
- 3x: 98.6%
- 10x: 97.3%
- 20x: 95.1%
|
| Validation Efficiency |
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 12 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Angptl4 |
G |
A |
17: 33,996,008 (GRCm39) |
P323S |
possibly damaging |
Het |
| Cdk5rap2 |
ATGTG |
ATG |
4: 70,208,214 (GRCm39) |
|
probably null |
Het |
| Dnajc16 |
T |
A |
4: 141,493,856 (GRCm39) |
K571* |
probably null |
Het |
| Gm10608 |
CAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGA |
CAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGA |
9: 118,989,784 (GRCm39) |
|
probably null |
Het |
| Gpd2 |
C |
T |
2: 57,228,987 (GRCm39) |
R264* |
probably null |
Het |
| H2-M2 |
T |
C |
17: 37,794,345 (GRCm39) |
T26A |
probably benign |
Het |
| Kirrel1 |
C |
T |
3: 86,996,458 (GRCm39) |
M380I |
probably null |
Het |
| Prpf39 |
T |
C |
12: 65,089,297 (GRCm39) |
S12P |
probably damaging |
Het |
| Prss1 |
G |
T |
6: 41,440,172 (GRCm39) |
D170Y |
probably damaging |
Het |
| Satb1 |
T |
C |
17: 52,082,331 (GRCm39) |
D441G |
possibly damaging |
Het |
| Tas2r106 |
A |
T |
6: 131,655,068 (GRCm39) |
L261* |
probably null |
Het |
| Zfp719 |
T |
A |
7: 43,239,851 (GRCm39) |
S480T |
possibly damaging |
Het |
|
| Other mutations in Gm5407 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL02416:Gm5407
|
APN |
16 |
49,117,250 (GRCm39) |
exon |
noncoding transcript |
|
|
IGL03110:Gm5407
|
APN |
16 |
49,117,757 (GRCm39) |
exon |
noncoding transcript |
|
|
R1913:Gm5407
|
UTSW |
16 |
49,117,283 (GRCm39) |
exon |
noncoding transcript |
|
|
R4728:Gm5407
|
UTSW |
16 |
49,117,283 (GRCm39) |
exon |
noncoding transcript |
|
|
R5771:Gm5407
|
UTSW |
16 |
49,117,229 (GRCm39) |
exon |
noncoding transcript |
|
|
R8292:Gm5407
|
UTSW |
16 |
49,117,550 (GRCm39) |
missense |
noncoding transcript |
|
|
| Predicted Primers |
PCR Primer
(F):5'- GTCCCTAGCGATGTAATCTGC -3'
(R):5'- CAAGGCTATCCACCTCTTCATG -3'
Sequencing Primer
(F):5'- TCCCATTCAGTTGCAGAGGAATC -3'
(R):5'- GGCTATCCACCTCTTCATGTCTTTAG -3'
|
| Posted On |
2014-12-29 |
Incidental Mutation