Incidental Mutation 'R0323:Lrriq1'
| ID |
25666 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Lrriq1
|
| Ensembl Gene |
ENSMUSG00000019892 |
| Gene Name |
leucine-rich repeats and IQ motif containing 1 |
| Synonyms |
Gm1557, LOC380658, 4930503E15Rik |
| MMRRC Submission |
038533-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.073)
|
| Stock # |
R0323 (G1)
|
| Quality Score |
225 |
|
Status
|
Not validated
|
| Chromosome |
10 |
| Chromosomal Location |
102881892-103072183 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to T
at 103057150 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Cysteine to Serine
at position 217
(C217S)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000131419
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000020043]
[ENSMUST00000123364]
[ENSMUST00000166240]
|
| AlphaFold |
Q0P5X1 |
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000020043
AA Change: C217S
PolyPhen 2
Score 0.909 (Sensitivity: 0.81; Specificity: 0.94)
|
| SMART Domains |
Protein: ENSMUSP00000020043
Gene: ENSMUSG00000019892
AA Change: C217S
| Domain | Start | End | E-Value | Type |
|---|
|
coiled coil region
|
11 |
31 |
N/A |
INTRINSIC |
|
low complexity region
|
35 |
48 |
N/A |
INTRINSIC |
|
coiled coil region
|
183 |
286 |
N/A |
INTRINSIC |
|
Blast:IQ
|
290 |
312 |
1e-6 |
BLAST |
|
coiled coil region
|
314 |
390 |
N/A |
INTRINSIC |
|
low complexity region
|
550 |
559 |
N/A |
INTRINSIC |
|
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000123364
AA Change: C217S
PolyPhen 2
Score 0.909 (Sensitivity: 0.81; Specificity: 0.94)
|
| SMART Domains |
Protein: ENSMUSP00000119783
Gene: ENSMUSG00000019892
AA Change: C217S
| Domain | Start | End | E-Value | Type |
|---|
|
coiled coil region
|
11 |
31 |
N/A |
INTRINSIC |
|
low complexity region
|
35 |
48 |
N/A |
INTRINSIC |
|
coiled coil region
|
183 |
286 |
N/A |
INTRINSIC |
|
Blast:IQ
|
290 |
312 |
6e-6 |
BLAST |
|
coiled coil region
|
314 |
390 |
N/A |
INTRINSIC |
|
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000166240
AA Change: C217S
PolyPhen 2
Score 0.909 (Sensitivity: 0.81; Specificity: 0.94)
|
| SMART Domains |
Protein: ENSMUSP00000131419
Gene: ENSMUSG00000019892
AA Change: C217S
| Domain | Start | End | E-Value | Type |
|---|
|
coiled coil region
|
11 |
31 |
N/A |
INTRINSIC |
|
low complexity region
|
35 |
48 |
N/A |
INTRINSIC |
|
coiled coil region
|
183 |
286 |
N/A |
INTRINSIC |
|
IQ
|
290 |
312 |
9.78e1 |
SMART |
|
coiled coil region
|
314 |
390 |
N/A |
INTRINSIC |
|
low complexity region
|
550 |
559 |
N/A |
INTRINSIC |
|
LRR
|
873 |
894 |
2.14e1 |
SMART |
|
LRR
|
895 |
917 |
4.45e1 |
SMART |
|
LRR
|
984 |
1005 |
2.03e2 |
SMART |
|
LRR
|
1029 |
1052 |
3.65e0 |
SMART |
|
low complexity region
|
1244 |
1258 |
N/A |
INTRINSIC |
|
IQ
|
1279 |
1301 |
5.61e1 |
SMART |
|
IQ
|
1339 |
1361 |
6.7e-3 |
SMART |
|
low complexity region
|
1369 |
1394 |
N/A |
INTRINSIC |
|
low complexity region
|
1502 |
1518 |
N/A |
INTRINSIC |
|
low complexity region
|
1528 |
1543 |
N/A |
INTRINSIC |
|
| Coding Region Coverage |
- 1x: 98.7%
- 3x: 97.5%
- 10x: 94.2%
- 20x: 86.1%
|
| Validation Efficiency |
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 92 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 2210408I21Rik |
A |
T |
13: 77,446,674 (GRCm39) |
T816S |
possibly damaging |
Het |
| 4930527J03Rik |
ACCC |
ACC |
1: 178,276,503 (GRCm38) |
|
noncoding transcript |
Het |
| 4931429P17Rik |
A |
C |
13: 48,114,493 (GRCm39) |
|
noncoding transcript |
Het |
| Abca13 |
A |
C |
11: 9,244,701 (GRCm39) |
D2188A |
probably benign |
Het |
| Accsl |
T |
A |
2: 93,691,425 (GRCm39) |
Q351L |
probably benign |
Het |
| Acot6 |
A |
C |
12: 84,155,953 (GRCm39) |
E300D |
probably benign |
Het |
| Adgre1 |
T |
A |
17: 57,751,060 (GRCm39) |
I578N |
probably benign |
Het |
| Agbl4 |
T |
C |
4: 111,474,419 (GRCm39) |
S403P |
probably damaging |
Het |
| Agps |
T |
A |
2: 75,724,505 (GRCm39) |
Y506* |
probably null |
Het |
| Appl1 |
A |
T |
14: 26,664,695 (GRCm39) |
V446D |
possibly damaging |
Het |
| Arcn1 |
A |
T |
9: 44,670,356 (GRCm39) |
I90N |
probably damaging |
Het |
| Aspscr1 |
G |
A |
11: 120,569,246 (GRCm39) |
V15I |
probably damaging |
Het |
| Asxl2 |
A |
G |
12: 3,492,487 (GRCm39) |
Y24C |
probably damaging |
Het |
| Atp8b1 |
A |
G |
18: 64,701,323 (GRCm39) |
F345S |
possibly damaging |
Het |
| Barx1 |
A |
G |
13: 48,819,430 (GRCm39) |
T243A |
probably benign |
Het |
| Bltp1 |
T |
A |
3: 36,997,331 (GRCm39) |
C1129* |
probably null |
Het |
| Bmp2k |
A |
G |
5: 97,235,682 (GRCm39) |
|
probably benign |
Het |
| Cacul1 |
A |
G |
19: 60,531,498 (GRCm39) |
I257T |
probably benign |
Het |
| Chml |
A |
T |
1: 175,514,650 (GRCm39) |
F424I |
probably benign |
Het |
| Clcn1 |
A |
T |
6: 42,287,074 (GRCm39) |
E710D |
probably damaging |
Het |
| Col1a2 |
G |
A |
6: 4,518,822 (GRCm39) |
|
probably benign |
Het |
| Cylc2 |
T |
A |
4: 51,228,477 (GRCm39) |
S183T |
unknown |
Het |
| Dhtkd1 |
T |
A |
2: 5,919,699 (GRCm39) |
M561L |
probably benign |
Het |
| Dnajc13 |
A |
G |
9: 104,034,091 (GRCm39) |
S2188P |
probably damaging |
Het |
| Dyrk1b |
C |
A |
7: 27,884,781 (GRCm39) |
Q399K |
probably benign |
Het |
| Erc1 |
T |
C |
6: 119,597,289 (GRCm39) |
K1003E |
probably damaging |
Het |
| Ezr |
G |
A |
17: 7,022,164 (GRCm39) |
Q105* |
probably null |
Het |
| Fam83d |
T |
A |
2: 158,627,467 (GRCm39) |
D385E |
probably benign |
Het |
| Fbn2 |
A |
G |
18: 58,178,389 (GRCm39) |
C1950R |
probably damaging |
Het |
| Fbxo32 |
A |
T |
15: 58,047,605 (GRCm39) |
I236N |
probably damaging |
Het |
| Fcgr1 |
T |
C |
3: 96,193,145 (GRCm39) |
E284G |
possibly damaging |
Het |
| Foxe3 |
T |
C |
4: 114,782,805 (GRCm39) |
N136D |
probably damaging |
Het |
| Fscn2 |
A |
T |
11: 120,258,837 (GRCm39) |
I461F |
probably damaging |
Het |
| Fsip2 |
T |
C |
2: 82,816,240 (GRCm39) |
I3991T |
probably benign |
Het |
| Galnt15 |
A |
T |
14: 31,770,042 (GRCm39) |
H249L |
probably damaging |
Het |
| Gm10803 |
T |
A |
2: 93,394,415 (GRCm39) |
Y62* |
probably null |
Het |
| Gm20730 |
G |
A |
6: 43,058,449 (GRCm39) |
|
probably null |
Het |
| Gm4841 |
A |
G |
18: 60,403,718 (GRCm39) |
L125S |
possibly damaging |
Het |
| Gmpr2 |
A |
G |
14: 55,910,203 (GRCm39) |
D11G |
probably damaging |
Het |
| Gucy1b1 |
T |
A |
3: 81,945,463 (GRCm39) |
|
probably null |
Het |
| Hhla1 |
C |
A |
15: 65,820,352 (GRCm39) |
V133F |
probably benign |
Het |
| Hscb |
T |
C |
5: 110,982,556 (GRCm39) |
E177G |
possibly damaging |
Het |
| Hyal4 |
A |
T |
6: 24,756,193 (GRCm39) |
N137I |
probably benign |
Het |
| Lcp2 |
A |
G |
11: 34,004,322 (GRCm39) |
D53G |
probably damaging |
Het |
| Ldb3 |
G |
A |
14: 34,266,002 (GRCm39) |
T531I |
probably damaging |
Het |
| Llgl2 |
A |
G |
11: 115,741,546 (GRCm39) |
K559E |
probably damaging |
Het |
| Loxhd1 |
A |
G |
18: 77,456,833 (GRCm39) |
I499V |
probably benign |
Het |
| Lrp2 |
T |
C |
2: 69,299,983 (GRCm39) |
Y3023C |
probably damaging |
Het |
| Lrrc59 |
A |
C |
11: 94,534,248 (GRCm39) |
T269P |
probably damaging |
Het |
| Mmrn2 |
A |
T |
14: 34,119,991 (GRCm39) |
Q287L |
probably damaging |
Het |
| Mplkip |
A |
G |
13: 17,871,565 (GRCm39) |
I159V |
possibly damaging |
Het |
| Napg |
C |
T |
18: 63,120,034 (GRCm39) |
R149C |
probably damaging |
Het |
| Nrxn1 |
A |
C |
17: 91,008,170 (GRCm39) |
|
probably null |
Het |
| Or10ag60 |
G |
A |
2: 87,437,841 (GRCm39) |
M36I |
probably benign |
Het |
| Or1e17 |
A |
T |
11: 73,831,773 (GRCm39) |
I234F |
probably benign |
Het |
| Or6c70 |
T |
A |
10: 129,709,936 (GRCm39) |
Q230L |
probably damaging |
Het |
| Or6d15 |
A |
T |
6: 116,559,562 (GRCm39) |
V115E |
probably damaging |
Het |
| Or6n2 |
A |
G |
1: 173,896,893 (GRCm39) |
T10A |
probably benign |
Het |
| Orc4 |
A |
T |
2: 48,827,479 (GRCm39) |
V38E |
possibly damaging |
Het |
| Palm3 |
T |
A |
8: 84,755,349 (GRCm39) |
V287D |
probably damaging |
Het |
| Pde11a |
C |
T |
2: 75,877,118 (GRCm39) |
|
probably null |
Het |
| Pdss2 |
T |
A |
10: 43,248,172 (GRCm39) |
H225Q |
probably benign |
Het |
| Pkhd1 |
A |
T |
1: 20,345,762 (GRCm39) |
D2755E |
probably benign |
Het |
| Pla2g5 |
C |
T |
4: 138,527,967 (GRCm39) |
D100N |
probably benign |
Het |
| Polrmt |
T |
C |
10: 79,577,832 (GRCm39) |
T287A |
probably benign |
Het |
| Ppfia2 |
A |
G |
10: 106,732,281 (GRCm39) |
I943V |
possibly damaging |
Het |
| Pth2r |
A |
C |
1: 65,427,775 (GRCm39) |
I483L |
probably benign |
Het |
| Qrsl1 |
A |
G |
10: 43,772,003 (GRCm39) |
|
probably null |
Het |
| Ralgapa1 |
A |
T |
12: 55,724,023 (GRCm39) |
I1548N |
probably damaging |
Het |
| Scn9a |
T |
C |
2: 66,398,475 (GRCm39) |
E45G |
probably damaging |
Het |
| Sf3b1 |
T |
C |
1: 55,058,416 (GRCm39) |
I58V |
probably damaging |
Het |
| Sh3d19 |
T |
A |
3: 86,033,978 (GRCm39) |
M777K |
probably benign |
Het |
| Shc1 |
T |
C |
3: 89,331,020 (GRCm39) |
L106P |
probably damaging |
Het |
| Skint5 |
T |
C |
4: 113,794,818 (GRCm39) |
H255R |
probably benign |
Het |
| Slc28a3 |
C |
A |
13: 58,711,866 (GRCm39) |
G487* |
probably null |
Het |
| Slc49a4 |
ACC |
AC |
16: 35,539,730 (GRCm39) |
|
probably null |
Het |
| Slfn4 |
A |
T |
11: 83,077,777 (GRCm39) |
R188S |
probably damaging |
Het |
| Slitrk5 |
A |
G |
14: 111,919,055 (GRCm39) |
D893G |
probably damaging |
Het |
| Spta1 |
A |
G |
1: 174,046,017 (GRCm39) |
T1594A |
probably damaging |
Het |
| Srarp |
G |
A |
4: 141,160,690 (GRCm39) |
Q48* |
probably null |
Het |
| Srf |
T |
C |
17: 46,860,415 (GRCm39) |
T456A |
possibly damaging |
Het |
| Stx2 |
C |
T |
5: 129,065,967 (GRCm39) |
V230I |
probably benign |
Het |
| Tenm4 |
C |
A |
7: 96,344,157 (GRCm39) |
P250Q |
possibly damaging |
Het |
| Tnrc6c |
A |
G |
11: 117,630,707 (GRCm39) |
K1023E |
probably damaging |
Het |
| Trpc6 |
A |
T |
9: 8,610,276 (GRCm39) |
H248L |
probably damaging |
Het |
| Trpc6 |
A |
G |
9: 8,643,537 (GRCm39) |
K441E |
probably damaging |
Het |
| Uty |
T |
A |
Y: 1,169,979 (GRCm39) |
I326F |
probably damaging |
Het |
| Vmn1r63 |
A |
G |
7: 5,806,335 (GRCm39) |
V99A |
probably benign |
Het |
| Wnt11 |
A |
G |
7: 98,496,590 (GRCm39) |
K177E |
probably damaging |
Het |
| Wwc1 |
T |
A |
11: 35,743,175 (GRCm39) |
E882V |
probably damaging |
Het |
| Zfhx2 |
C |
A |
14: 55,303,436 (GRCm39) |
S1516I |
possibly damaging |
Het |
| Zmpste24 |
A |
G |
4: 120,940,050 (GRCm39) |
Y199H |
probably damaging |
Het |
|
| Other mutations in Lrriq1 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00988:Lrriq1
|
APN |
10 |
102,997,757 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL01523:Lrriq1
|
APN |
10 |
103,053,977 (GRCm39) |
nonsense |
probably null |
|
|
IGL01637:Lrriq1
|
APN |
10 |
103,051,489 (GRCm39) |
missense |
probably benign |
|
|
IGL02019:Lrriq1
|
APN |
10 |
103,014,661 (GRCm39) |
missense |
probably benign |
0.02 |
|
IGL02153:Lrriq1
|
APN |
10 |
103,006,340 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL02341:Lrriq1
|
APN |
10 |
103,060,802 (GRCm39) |
missense |
probably benign |
0.03 |
|
IGL02343:Lrriq1
|
APN |
10 |
103,070,024 (GRCm39) |
splice site |
probably benign |
|
|
IGL02408:Lrriq1
|
APN |
10 |
102,982,142 (GRCm39) |
missense |
probably benign |
0.17 |
|
IGL02431:Lrriq1
|
APN |
10 |
103,036,500 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02540:Lrriq1
|
APN |
10 |
103,050,880 (GRCm39) |
missense |
probably benign |
0.02 |
|
IGL02558:Lrriq1
|
APN |
10 |
102,982,144 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02613:Lrriq1
|
APN |
10 |
102,980,409 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL02642:Lrriq1
|
APN |
10 |
103,057,322 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
IGL03027:Lrriq1
|
APN |
10 |
103,063,057 (GRCm39) |
missense |
probably benign |
0.35 |
|
PIT4362001:Lrriq1
|
UTSW |
10 |
102,907,055 (GRCm39) |
missense |
probably benign |
0.26 |
|
R0050:Lrriq1
|
UTSW |
10 |
102,904,792 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0050:Lrriq1
|
UTSW |
10 |
102,904,792 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0068:Lrriq1
|
UTSW |
10 |
102,899,279 (GRCm39) |
missense |
probably benign |
0.02 |
|
R0068:Lrriq1
|
UTSW |
10 |
102,899,279 (GRCm39) |
missense |
probably benign |
0.02 |
|
R0124:Lrriq1
|
UTSW |
10 |
103,006,281 (GRCm39) |
critical splice donor site |
probably null |
|
|
R0244:Lrriq1
|
UTSW |
10 |
103,051,634 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R0515:Lrriq1
|
UTSW |
10 |
102,904,829 (GRCm39) |
splice site |
probably null |
|
|
R0522:Lrriq1
|
UTSW |
10 |
102,997,638 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0701:Lrriq1
|
UTSW |
10 |
103,069,905 (GRCm39) |
missense |
probably benign |
|
|
R1220:Lrriq1
|
UTSW |
10 |
102,906,990 (GRCm39) |
missense |
probably benign |
0.05 |
|
R1261:Lrriq1
|
UTSW |
10 |
103,069,998 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
R1262:Lrriq1
|
UTSW |
10 |
103,069,998 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
R1451:Lrriq1
|
UTSW |
10 |
103,038,376 (GRCm39) |
splice site |
probably benign |
|
|
R1642:Lrriq1
|
UTSW |
10 |
103,050,317 (GRCm39) |
missense |
probably benign |
0.13 |
|
R1643:Lrriq1
|
UTSW |
10 |
103,050,685 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1647:Lrriq1
|
UTSW |
10 |
103,006,509 (GRCm39) |
nonsense |
probably null |
|
|
R1830:Lrriq1
|
UTSW |
10 |
102,997,620 (GRCm39) |
missense |
probably benign |
|
|
R1843:Lrriq1
|
UTSW |
10 |
103,063,034 (GRCm39) |
splice site |
probably null |
|
|
R2128:Lrriq1
|
UTSW |
10 |
103,050,718 (GRCm39) |
missense |
probably benign |
0.01 |
|
R2129:Lrriq1
|
UTSW |
10 |
103,050,718 (GRCm39) |
missense |
probably benign |
0.01 |
|
R2199:Lrriq1
|
UTSW |
10 |
102,904,774 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2354:Lrriq1
|
UTSW |
10 |
103,025,848 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2495:Lrriq1
|
UTSW |
10 |
103,038,242 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R2897:Lrriq1
|
UTSW |
10 |
103,063,111 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R2898:Lrriq1
|
UTSW |
10 |
103,063,111 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R2922:Lrriq1
|
UTSW |
10 |
103,050,536 (GRCm39) |
missense |
probably benign |
0.00 |
|
R2939:Lrriq1
|
UTSW |
10 |
102,980,750 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R2965:Lrriq1
|
UTSW |
10 |
103,050,761 (GRCm39) |
missense |
probably benign |
0.07 |
|
R2966:Lrriq1
|
UTSW |
10 |
103,050,761 (GRCm39) |
missense |
probably benign |
0.07 |
|
R3081:Lrriq1
|
UTSW |
10 |
102,980,750 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R3115:Lrriq1
|
UTSW |
10 |
103,006,294 (GRCm39) |
missense |
probably benign |
0.00 |
|
R3745:Lrriq1
|
UTSW |
10 |
103,006,717 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R3813:Lrriq1
|
UTSW |
10 |
103,051,972 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3814:Lrriq1
|
UTSW |
10 |
103,051,972 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3885:Lrriq1
|
UTSW |
10 |
103,051,967 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R4378:Lrriq1
|
UTSW |
10 |
103,038,225 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4632:Lrriq1
|
UTSW |
10 |
103,057,288 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4633:Lrriq1
|
UTSW |
10 |
103,036,424 (GRCm39) |
nonsense |
probably null |
|
|
R4663:Lrriq1
|
UTSW |
10 |
102,899,273 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
R4702:Lrriq1
|
UTSW |
10 |
103,051,610 (GRCm39) |
missense |
possibly damaging |
0.65 |
|
R4793:Lrriq1
|
UTSW |
10 |
103,006,327 (GRCm39) |
missense |
probably benign |
0.25 |
|
R4801:Lrriq1
|
UTSW |
10 |
103,057,179 (GRCm39) |
missense |
probably benign |
0.02 |
|
R4802:Lrriq1
|
UTSW |
10 |
103,057,179 (GRCm39) |
missense |
probably benign |
0.02 |
|
R4815:Lrriq1
|
UTSW |
10 |
102,980,739 (GRCm39) |
missense |
probably benign |
0.10 |
|
R4872:Lrriq1
|
UTSW |
10 |
103,014,649 (GRCm39) |
missense |
possibly damaging |
0.56 |
|
R4877:Lrriq1
|
UTSW |
10 |
103,069,899 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
R4894:Lrriq1
|
UTSW |
10 |
102,997,613 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
R4990:Lrriq1
|
UTSW |
10 |
103,036,420 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4991:Lrriq1
|
UTSW |
10 |
103,036,420 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5011:Lrriq1
|
UTSW |
10 |
103,025,784 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5013:Lrriq1
|
UTSW |
10 |
103,025,784 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5122:Lrriq1
|
UTSW |
10 |
103,023,314 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5282:Lrriq1
|
UTSW |
10 |
103,051,206 (GRCm39) |
missense |
probably benign |
0.01 |
|
R5311:Lrriq1
|
UTSW |
10 |
103,050,448 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5567:Lrriq1
|
UTSW |
10 |
103,006,457 (GRCm39) |
missense |
possibly damaging |
0.56 |
|
R5643:Lrriq1
|
UTSW |
10 |
103,051,301 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5683:Lrriq1
|
UTSW |
10 |
103,009,236 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5916:Lrriq1
|
UTSW |
10 |
103,057,243 (GRCm39) |
nonsense |
probably null |
|
|
R6008:Lrriq1
|
UTSW |
10 |
103,006,325 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6022:Lrriq1
|
UTSW |
10 |
103,051,395 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R6224:Lrriq1
|
UTSW |
10 |
103,051,618 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6254:Lrriq1
|
UTSW |
10 |
103,051,312 (GRCm39) |
missense |
probably benign |
0.15 |
|
R6311:Lrriq1
|
UTSW |
10 |
103,009,254 (GRCm39) |
missense |
probably benign |
0.03 |
|
R6460:Lrriq1
|
UTSW |
10 |
103,036,559 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6502:Lrriq1
|
UTSW |
10 |
103,063,045 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6637:Lrriq1
|
UTSW |
10 |
103,057,293 (GRCm39) |
missense |
probably benign |
0.06 |
|
R6719:Lrriq1
|
UTSW |
10 |
102,906,977 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6736:Lrriq1
|
UTSW |
10 |
103,017,750 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R6928:Lrriq1
|
UTSW |
10 |
103,050,800 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R6991:Lrriq1
|
UTSW |
10 |
103,023,319 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7174:Lrriq1
|
UTSW |
10 |
103,060,826 (GRCm39) |
missense |
probably benign |
|
|
R7241:Lrriq1
|
UTSW |
10 |
103,051,834 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7248:Lrriq1
|
UTSW |
10 |
103,059,611 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R7287:Lrriq1
|
UTSW |
10 |
103,051,877 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7402:Lrriq1
|
UTSW |
10 |
103,057,185 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
R7439:Lrriq1
|
UTSW |
10 |
103,050,380 (GRCm39) |
missense |
probably benign |
0.21 |
|
R7585:Lrriq1
|
UTSW |
10 |
103,050,807 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R7611:Lrriq1
|
UTSW |
10 |
103,036,432 (GRCm39) |
missense |
possibly damaging |
0.54 |
|
R7634:Lrriq1
|
UTSW |
10 |
103,036,462 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7767:Lrriq1
|
UTSW |
10 |
103,051,815 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7809:Lrriq1
|
UTSW |
10 |
103,051,678 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7910:Lrriq1
|
UTSW |
10 |
103,051,055 (GRCm39) |
nonsense |
probably null |
|
|
R8131:Lrriq1
|
UTSW |
10 |
103,051,572 (GRCm39) |
missense |
possibly damaging |
0.57 |
|
R8156:Lrriq1
|
UTSW |
10 |
102,992,196 (GRCm39) |
critical splice donor site |
probably null |
|
|
R8211:Lrriq1
|
UTSW |
10 |
103,006,408 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8304:Lrriq1
|
UTSW |
10 |
103,069,929 (GRCm39) |
missense |
possibly damaging |
0.57 |
|
R8487:Lrriq1
|
UTSW |
10 |
103,050,914 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R8500:Lrriq1
|
UTSW |
10 |
102,882,016 (GRCm39) |
missense |
|
|
|
R9013:Lrriq1
|
UTSW |
10 |
103,050,931 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9099:Lrriq1
|
UTSW |
10 |
103,051,864 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R9155:Lrriq1
|
UTSW |
10 |
103,050,640 (GRCm39) |
missense |
probably benign |
0.03 |
|
R9320:Lrriq1
|
UTSW |
10 |
103,057,144 (GRCm39) |
missense |
probably benign |
|
|
R9384:Lrriq1
|
UTSW |
10 |
103,006,458 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9469:Lrriq1
|
UTSW |
10 |
103,050,761 (GRCm39) |
missense |
probably benign |
0.07 |
|
R9585:Lrriq1
|
UTSW |
10 |
103,051,250 (GRCm39) |
missense |
probably benign |
|
|
R9706:Lrriq1
|
UTSW |
10 |
102,881,902 (GRCm39) |
missense |
|
|
|
R9780:Lrriq1
|
UTSW |
10 |
103,025,824 (GRCm39) |
missense |
probably damaging |
1.00 |
|
X0026:Lrriq1
|
UTSW |
10 |
103,051,565 (GRCm39) |
nonsense |
probably null |
|
|
Z1088:Lrriq1
|
UTSW |
10 |
103,038,307 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1176:Lrriq1
|
UTSW |
10 |
103,069,946 (GRCm39) |
missense |
probably damaging |
0.99 |
|
Z1176:Lrriq1
|
UTSW |
10 |
103,038,221 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1176:Lrriq1
|
UTSW |
10 |
103,038,220 (GRCm39) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- TGGCCTCCAGGATCAAGAGTTCAC -3'
(R):5'- CACGCTTGTTTCTCTGAACGAATGC -3'
Sequencing Primer
(F):5'- TGAAGACTTACTCCATGAGCAG -3'
(R):5'- GTTTCTCTGAACGAATGCAGATGAG -3'
|
| Posted On |
2013-04-16 |
Incidental Mutation