Incidental Mutation 'R0331:Shprh'
| ID |
26068 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Shprh
|
| Ensembl Gene |
ENSMUSG00000090112 |
| Gene Name |
SNF2 histone linker PHD RING helicase |
| Synonyms |
2610103K11Rik, D230017O13Rik |
| MMRRC Submission |
038540-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R0331 (G1)
|
| Quality Score |
215 |
|
Status
|
Validated
|
| Chromosome |
10 |
| Chromosomal Location |
11025171-11093339 bp(+) (GRCm39) |
| Type of Mutation |
splice site |
| DNA Base Change (assembly) |
T to C
at 11069914 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000132870
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000044053]
[ENSMUST00000054814]
[ENSMUST00000159541]
|
| AlphaFold |
Q7TPQ3 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000044053
|
| SMART Domains |
Protein: ENSMUSP00000039422
Gene: ENSMUSG00000090112
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
42 |
56 |
N/A |
INTRINSIC |
|
Blast:DEXDc
|
195 |
250 |
3e-12 |
BLAST |
|
low complexity region
|
253 |
265 |
N/A |
INTRINSIC |
|
DEXDc
|
295 |
866 |
4.02e-17 |
SMART |
|
H15
|
431 |
497 |
3.76e-5 |
SMART |
|
PHD
|
651 |
698 |
2.33e-5 |
SMART |
|
low complexity region
|
1393 |
1404 |
N/A |
INTRINSIC |
|
RING
|
1423 |
1469 |
9.68e-3 |
SMART |
|
Pfam:Helicase_C
|
1500 |
1613 |
1.6e-8 |
PFAM |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000054814
|
| SMART Domains |
Protein: ENSMUSP00000125849
Gene: ENSMUSG00000090112
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
42 |
56 |
N/A |
INTRINSIC |
|
Blast:DEXDc
|
195 |
250 |
3e-12 |
BLAST |
|
low complexity region
|
253 |
265 |
N/A |
INTRINSIC |
|
DEXDc
|
295 |
866 |
4.02e-17 |
SMART |
|
H15
|
431 |
497 |
3.76e-5 |
SMART |
|
PHD
|
651 |
698 |
2.33e-5 |
SMART |
|
low complexity region
|
1393 |
1404 |
N/A |
INTRINSIC |
|
RING
|
1423 |
1469 |
9.68e-3 |
SMART |
|
SCOP:d1fuka_
|
1504 |
1616 |
6e-8 |
SMART |
|
Blast:HELICc
|
1533 |
1613 |
4e-46 |
BLAST |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000159541
|
| SMART Domains |
Protein: ENSMUSP00000132870
Gene: ENSMUSG00000090112
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
42 |
56 |
N/A |
INTRINSIC |
|
Blast:DEXDc
|
195 |
250 |
3e-12 |
BLAST |
|
low complexity region
|
253 |
265 |
N/A |
INTRINSIC |
|
DEXDc
|
295 |
866 |
4.02e-17 |
SMART |
|
H15
|
431 |
497 |
3.76e-5 |
SMART |
|
PHD
|
651 |
698 |
2.33e-5 |
SMART |
|
low complexity region
|
1393 |
1404 |
N/A |
INTRINSIC |
|
RING
|
1423 |
1469 |
9.68e-3 |
SMART |
|
SCOP:d1fuka_
|
1504 |
1619 |
4e-8 |
SMART |
|
Blast:HELICc
|
1533 |
1613 |
6e-46 |
BLAST |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000159553
|
| Coding Region Coverage |
- 1x: 99.0%
- 3x: 98.0%
- 10x: 95.8%
- 20x: 91.7%
|
| Validation Efficiency |
100% (81/81) |
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] SHPRH is a ubiquitously expressed protein that contains motifs characteristics of several DNA repair proteins, transcription factors, and helicases. SHPRH is a functional homolog of S. cerevisiae RAD5 (Unk et al., 2006 [PubMed 17108083]).[supplied by OMIM, Mar 2008]
PHENOTYPE: The gene product is an E3 ligase involved in poly-ubiquitination of Pcna. Neither homozygous truncation nor KO affect B cell somatic hypermutation or class switching. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 80 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 1700011L22Rik |
T |
A |
8: 79,956,021 (GRCm39) |
T79S |
probably benign |
Het |
| Abtb1 |
T |
C |
6: 88,817,684 (GRCm39) |
|
probably benign |
Het |
| Acot12 |
G |
A |
13: 91,908,183 (GRCm39) |
|
probably null |
Het |
| Adamts4 |
T |
A |
1: 171,078,541 (GRCm39) |
S54T |
probably benign |
Het |
| Adgrl4 |
T |
C |
3: 151,203,577 (GRCm39) |
S96P |
probably benign |
Het |
| Aip |
G |
T |
19: 4,168,247 (GRCm39) |
T40K |
probably damaging |
Het |
| Anapc4 |
A |
G |
5: 53,012,984 (GRCm39) |
|
probably benign |
Het |
| Asz1 |
A |
G |
6: 18,103,618 (GRCm39) |
|
probably benign |
Het |
| Atf7ip |
A |
G |
6: 136,538,161 (GRCm39) |
T465A |
possibly damaging |
Het |
| Atp11a |
C |
T |
8: 12,866,953 (GRCm39) |
Q127* |
probably null |
Het |
| Axin1 |
A |
G |
17: 26,362,081 (GRCm39) |
R142G |
probably damaging |
Het |
| Bcat1 |
T |
A |
6: 144,993,040 (GRCm39) |
E86V |
probably benign |
Het |
| Brd4 |
G |
A |
17: 32,421,489 (GRCm39) |
P749L |
probably benign |
Het |
| C1ra |
G |
A |
6: 124,496,394 (GRCm39) |
|
probably null |
Het |
| Capza2 |
A |
T |
6: 17,665,102 (GRCm39) |
N237I |
probably benign |
Het |
| Cd2ap |
A |
T |
17: 43,116,192 (GRCm39) |
V556E |
probably benign |
Het |
| Cfap65 |
G |
A |
1: 74,968,460 (GRCm39) |
P124L |
probably damaging |
Het |
| Cfap65 |
G |
T |
1: 74,968,461 (GRCm39) |
P124T |
probably damaging |
Het |
| Cftr |
T |
C |
6: 18,235,225 (GRCm39) |
V488A |
possibly damaging |
Het |
| Ckmt1 |
A |
T |
2: 121,193,337 (GRCm39) |
|
probably null |
Het |
| Cmya5 |
T |
G |
13: 93,280,911 (GRCm39) |
E35A |
possibly damaging |
Het |
| Col7a1 |
A |
G |
9: 108,796,570 (GRCm39) |
|
probably benign |
Het |
| Crmp1 |
C |
T |
5: 37,422,657 (GRCm39) |
L155F |
possibly damaging |
Het |
| Cyp2d10 |
T |
A |
15: 82,291,227 (GRCm39) |
T33S |
probably benign |
Het |
| Dhdh |
T |
C |
7: 45,137,544 (GRCm39) |
K48E |
probably benign |
Het |
| Dlst |
T |
C |
12: 85,165,586 (GRCm39) |
V103A |
probably damaging |
Het |
| Dohh |
C |
T |
10: 81,223,646 (GRCm39) |
T233I |
probably benign |
Het |
| Dvl2 |
C |
A |
11: 69,897,043 (GRCm39) |
|
probably benign |
Het |
| Eipr1 |
C |
T |
12: 28,914,703 (GRCm39) |
Q286* |
probably null |
Het |
| Enpp6 |
C |
A |
8: 47,535,484 (GRCm39) |
T343K |
probably damaging |
Het |
| Fbxw11 |
T |
A |
11: 32,661,895 (GRCm39) |
F112I |
probably damaging |
Het |
| Gdpd4 |
T |
A |
7: 97,622,215 (GRCm39) |
N231K |
probably benign |
Het |
| Gm6370 |
A |
T |
5: 146,430,576 (GRCm39) |
T254S |
probably benign |
Het |
| Hapln4 |
G |
T |
8: 70,537,159 (GRCm39) |
Q31H |
probably damaging |
Het |
| Hic1 |
T |
A |
11: 75,056,316 (GRCm39) |
T858S |
possibly damaging |
Het |
| Isg20l2 |
T |
C |
3: 87,839,092 (GRCm39) |
L101P |
probably damaging |
Het |
| Itga10 |
T |
C |
3: 96,559,799 (GRCm39) |
Y485H |
probably damaging |
Het |
| Itgal |
T |
A |
7: 126,905,853 (GRCm39) |
|
probably null |
Het |
| Itln1 |
T |
C |
1: 171,359,117 (GRCm39) |
N62S |
probably damaging |
Het |
| Kdm4b |
T |
C |
17: 56,693,289 (GRCm39) |
|
probably benign |
Het |
| Lct |
T |
C |
1: 128,226,479 (GRCm39) |
|
probably benign |
Het |
| Lman2 |
A |
T |
13: 55,500,829 (GRCm39) |
H123Q |
probably damaging |
Het |
| Lztr1 |
T |
A |
16: 17,342,101 (GRCm39) |
|
probably benign |
Het |
| Myo3b |
G |
T |
2: 69,925,605 (GRCm39) |
G24V |
probably damaging |
Het |
| Nacad |
T |
A |
11: 6,549,441 (GRCm39) |
Q1250L |
possibly damaging |
Het |
| Ncor2 |
A |
T |
5: 125,161,981 (GRCm39) |
M431K |
unknown |
Het |
| Nek9 |
T |
A |
12: 85,374,149 (GRCm39) |
|
probably benign |
Het |
| Neu1 |
C |
A |
17: 35,153,146 (GRCm39) |
N255K |
possibly damaging |
Het |
| Nf2 |
T |
A |
11: 4,744,914 (GRCm39) |
T75S |
probably benign |
Het |
| Nipal4 |
T |
A |
11: 46,041,040 (GRCm39) |
D385V |
probably damaging |
Het |
| Olah |
T |
A |
2: 3,343,511 (GRCm39) |
N245I |
probably damaging |
Het |
| Or5p54 |
G |
T |
7: 107,554,077 (GRCm39) |
L76F |
probably benign |
Het |
| Pag1 |
T |
A |
3: 9,767,030 (GRCm39) |
T90S |
probably benign |
Het |
| Pald1 |
A |
G |
10: 61,176,708 (GRCm39) |
|
probably null |
Het |
| Parva |
A |
G |
7: 112,144,005 (GRCm39) |
M98V |
probably benign |
Het |
| Paxbp1 |
T |
A |
16: 90,834,255 (GRCm39) |
D177V |
possibly damaging |
Het |
| Paxip1 |
A |
G |
5: 27,970,230 (GRCm39) |
I587T |
probably damaging |
Het |
| Pclo |
T |
C |
5: 14,730,390 (GRCm39) |
|
probably benign |
Het |
| Pdgfra |
T |
A |
5: 75,355,713 (GRCm39) |
D1074E |
probably damaging |
Het |
| Pef1 |
A |
T |
4: 130,021,241 (GRCm39) |
D265V |
probably damaging |
Het |
| Plekhh2 |
G |
A |
17: 84,893,794 (GRCm39) |
E870K |
possibly damaging |
Het |
| Plscr4 |
G |
A |
9: 92,364,695 (GRCm39) |
G40D |
probably damaging |
Het |
| Psg18 |
A |
G |
7: 18,087,233 (GRCm39) |
Y142H |
probably benign |
Het |
| Ptchd3 |
A |
T |
11: 121,733,017 (GRCm39) |
M636L |
probably benign |
Het |
| Rab2a |
A |
G |
4: 8,572,559 (GRCm39) |
D51G |
probably benign |
Het |
| Rnf139 |
T |
A |
15: 58,771,755 (GRCm39) |
D593E |
probably benign |
Het |
| Septin7 |
A |
G |
9: 25,217,552 (GRCm39) |
N422S |
probably benign |
Het |
| Slc7a6os |
A |
G |
8: 106,937,199 (GRCm39) |
I87T |
probably damaging |
Het |
| Slc7a7 |
A |
G |
14: 54,615,381 (GRCm39) |
|
probably benign |
Het |
| Spc24 |
G |
T |
9: 21,668,609 (GRCm39) |
N129K |
possibly damaging |
Het |
| Strip2 |
C |
T |
6: 29,926,559 (GRCm39) |
T148I |
probably benign |
Het |
| Tmem150c |
A |
C |
5: 100,234,132 (GRCm39) |
|
probably null |
Het |
| Trav13-5 |
A |
G |
14: 54,033,205 (GRCm39) |
N38S |
probably benign |
Het |
| Ttn |
G |
T |
2: 76,641,364 (GRCm39) |
Y11801* |
probably null |
Het |
| Usp37 |
A |
T |
1: 74,493,223 (GRCm39) |
L688* |
probably null |
Het |
| Usp38 |
T |
C |
8: 81,722,469 (GRCm39) |
I351V |
probably benign |
Het |
| Vav2 |
T |
A |
2: 27,186,187 (GRCm39) |
M223L |
probably benign |
Het |
| Wdr36 |
A |
G |
18: 32,985,968 (GRCm39) |
I557M |
possibly damaging |
Het |
| Wwc2 |
A |
T |
8: 48,333,239 (GRCm39) |
M259K |
probably benign |
Het |
| Znfx1 |
G |
A |
2: 166,888,898 (GRCm39) |
S770L |
probably benign |
Het |
|
| Other mutations in Shprh |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00492:Shprh
|
APN |
10 |
11,063,902 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL00583:Shprh
|
APN |
10 |
11,063,764 (GRCm39) |
missense |
probably benign |
0.37 |
|
IGL00684:Shprh
|
APN |
10 |
11,038,781 (GRCm39) |
missense |
probably benign |
0.11 |
|
IGL01295:Shprh
|
APN |
10 |
11,059,612 (GRCm39) |
missense |
probably damaging |
0.96 |
|
IGL01387:Shprh
|
APN |
10 |
11,045,998 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01635:Shprh
|
APN |
10 |
11,045,763 (GRCm39) |
nonsense |
probably null |
|
|
IGL01833:Shprh
|
APN |
10 |
11,066,806 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02013:Shprh
|
APN |
10 |
11,057,246 (GRCm39) |
splice site |
probably benign |
|
|
IGL02502:Shprh
|
APN |
10 |
11,070,101 (GRCm39) |
missense |
possibly damaging |
0.66 |
|
IGL02819:Shprh
|
APN |
10 |
11,030,509 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
PIT4581001:Shprh
|
UTSW |
10 |
11,068,238 (GRCm39) |
frame shift |
probably null |
|
|
R0010:Shprh
|
UTSW |
10 |
11,027,675 (GRCm39) |
missense |
probably benign |
|
|
R0010:Shprh
|
UTSW |
10 |
11,027,675 (GRCm39) |
missense |
probably benign |
|
|
R0053:Shprh
|
UTSW |
10 |
11,070,116 (GRCm39) |
splice site |
probably null |
|
|
R0053:Shprh
|
UTSW |
10 |
11,070,116 (GRCm39) |
splice site |
probably null |
|
|
R0255:Shprh
|
UTSW |
10 |
11,062,135 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R0325:Shprh
|
UTSW |
10 |
11,045,853 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0494:Shprh
|
UTSW |
10 |
11,032,935 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0532:Shprh
|
UTSW |
10 |
11,038,556 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R0546:Shprh
|
UTSW |
10 |
11,059,631 (GRCm39) |
splice site |
probably benign |
|
|
R0574:Shprh
|
UTSW |
10 |
11,038,821 (GRCm39) |
unclassified |
probably benign |
|
|
R0605:Shprh
|
UTSW |
10 |
11,082,856 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0662:Shprh
|
UTSW |
10 |
11,062,591 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1148:Shprh
|
UTSW |
10 |
11,089,226 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R1148:Shprh
|
UTSW |
10 |
11,089,226 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R1263:Shprh
|
UTSW |
10 |
11,035,274 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1588:Shprh
|
UTSW |
10 |
11,040,488 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1638:Shprh
|
UTSW |
10 |
11,032,822 (GRCm39) |
missense |
probably benign |
|
|
R1830:Shprh
|
UTSW |
10 |
11,062,655 (GRCm39) |
splice site |
probably null |
|
|
R1898:Shprh
|
UTSW |
10 |
11,062,613 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1903:Shprh
|
UTSW |
10 |
11,059,541 (GRCm39) |
nonsense |
probably null |
|
|
R2060:Shprh
|
UTSW |
10 |
11,027,864 (GRCm39) |
missense |
probably benign |
0.03 |
|
R2225:Shprh
|
UTSW |
10 |
11,037,979 (GRCm39) |
unclassified |
probably benign |
|
|
R2363:Shprh
|
UTSW |
10 |
11,047,697 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2509:Shprh
|
UTSW |
10 |
11,042,468 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2891:Shprh
|
UTSW |
10 |
11,040,100 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3077:Shprh
|
UTSW |
10 |
11,046,157 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3150:Shprh
|
UTSW |
10 |
11,045,774 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R3796:Shprh
|
UTSW |
10 |
11,054,501 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R4196:Shprh
|
UTSW |
10 |
11,083,604 (GRCm39) |
utr 3 prime |
probably benign |
|
|
R4423:Shprh
|
UTSW |
10 |
11,062,262 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
R4488:Shprh
|
UTSW |
10 |
11,036,215 (GRCm39) |
missense |
probably benign |
0.17 |
|
R4748:Shprh
|
UTSW |
10 |
11,046,220 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4768:Shprh
|
UTSW |
10 |
11,057,284 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R4867:Shprh
|
UTSW |
10 |
11,040,301 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4937:Shprh
|
UTSW |
10 |
11,032,863 (GRCm39) |
missense |
probably benign |
|
|
R5140:Shprh
|
UTSW |
10 |
11,030,449 (GRCm39) |
missense |
probably benign |
0.03 |
|
R5318:Shprh
|
UTSW |
10 |
11,042,301 (GRCm39) |
missense |
probably benign |
0.04 |
|
R5323:Shprh
|
UTSW |
10 |
11,046,041 (GRCm39) |
splice site |
probably null |
|
|
R5450:Shprh
|
UTSW |
10 |
11,088,074 (GRCm39) |
missense |
possibly damaging |
0.70 |
|
R5872:Shprh
|
UTSW |
10 |
11,063,817 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6030:Shprh
|
UTSW |
10 |
11,027,735 (GRCm39) |
missense |
probably benign |
0.37 |
|
R6030:Shprh
|
UTSW |
10 |
11,027,735 (GRCm39) |
missense |
probably benign |
0.37 |
|
R6392:Shprh
|
UTSW |
10 |
11,054,485 (GRCm39) |
nonsense |
probably null |
|
|
R6416:Shprh
|
UTSW |
10 |
11,043,617 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6470:Shprh
|
UTSW |
10 |
11,047,681 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R6513:Shprh
|
UTSW |
10 |
11,062,637 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6530:Shprh
|
UTSW |
10 |
11,070,011 (GRCm39) |
missense |
probably benign |
0.02 |
|
R6678:Shprh
|
UTSW |
10 |
11,042,289 (GRCm39) |
missense |
probably benign |
0.16 |
|
R6757:Shprh
|
UTSW |
10 |
11,057,252 (GRCm39) |
splice site |
probably null |
|
|
R6971:Shprh
|
UTSW |
10 |
11,042,437 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7158:Shprh
|
UTSW |
10 |
11,042,474 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R7582:Shprh
|
UTSW |
10 |
11,040,449 (GRCm39) |
missense |
probably benign |
|
|
R7757:Shprh
|
UTSW |
10 |
11,037,924 (GRCm39) |
missense |
probably benign |
0.30 |
|
R7812:Shprh
|
UTSW |
10 |
11,027,735 (GRCm39) |
missense |
probably benign |
|
|
R7998:Shprh
|
UTSW |
10 |
11,061,085 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8061:Shprh
|
UTSW |
10 |
11,088,077 (GRCm39) |
missense |
possibly damaging |
0.71 |
|
R8082:Shprh
|
UTSW |
10 |
11,027,555 (GRCm39) |
missense |
probably benign |
0.22 |
|
R8116:Shprh
|
UTSW |
10 |
11,089,205 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8390:Shprh
|
UTSW |
10 |
11,063,727 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R8445:Shprh
|
UTSW |
10 |
11,057,313 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R8530:Shprh
|
UTSW |
10 |
11,027,678 (GRCm39) |
missense |
probably benign |
0.37 |
|
R8759:Shprh
|
UTSW |
10 |
11,032,908 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R8937:Shprh
|
UTSW |
10 |
11,061,181 (GRCm39) |
missense |
possibly damaging |
0.60 |
|
R8995:Shprh
|
UTSW |
10 |
11,040,574 (GRCm39) |
nonsense |
probably null |
|
|
R9053:Shprh
|
UTSW |
10 |
11,030,446 (GRCm39) |
missense |
probably benign |
0.04 |
|
R9131:Shprh
|
UTSW |
10 |
11,038,589 (GRCm39) |
missense |
possibly damaging |
0.58 |
|
R9176:Shprh
|
UTSW |
10 |
11,036,320 (GRCm39) |
missense |
probably benign |
0.02 |
|
R9391:Shprh
|
UTSW |
10 |
11,038,633 (GRCm39) |
missense |
probably benign |
0.05 |
|
R9423:Shprh
|
UTSW |
10 |
11,081,007 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9563:Shprh
|
UTSW |
10 |
11,042,235 (GRCm39) |
nonsense |
probably null |
|
|
R9668:Shprh
|
UTSW |
10 |
11,082,076 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R9709:Shprh
|
UTSW |
10 |
11,038,574 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R9718:Shprh
|
UTSW |
10 |
11,089,248 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9750:Shprh
|
UTSW |
10 |
11,040,204 (GRCm39) |
missense |
probably damaging |
0.98 |
|
RF012:Shprh
|
UTSW |
10 |
11,040,585 (GRCm39) |
missense |
probably benign |
0.02 |
|
V8831:Shprh
|
UTSW |
10 |
11,062,606 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1176:Shprh
|
UTSW |
10 |
11,062,191 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1176:Shprh
|
UTSW |
10 |
11,040,297 (GRCm39) |
missense |
probably benign |
|
|
Z1177:Shprh
|
UTSW |
10 |
11,027,506 (GRCm39) |
frame shift |
probably null |
|
|
| Predicted Primers |
PCR Primer
(F):5'- GCTGAGAGCCTAAAACCCATTGCC -3'
(R):5'- TACGCTCACTGTGCCAACTGTC -3'
Sequencing Primer
(F):5'- CAGTTCTGCATTATCTGCTGTTAAG -3'
(R):5'- CACAGGGATATCATCCTCTTGG -3'
|
| Posted On |
2013-04-16 |
Incidental Mutation