Mutagenetix > Incidental Mutation

Incidental Mutation 'R3087:Gm7275'

262876

Institutional Source

Beutler Lab

Gene Symbol

Gm7275

Ensembl Gene

ENSMUSG00000067716

Gene Name

predicted gene 7275

Synonyms

MMRRC Submission

040576-MU

Accession Numbers

Essential gene?

Possibly non essential (E-score: 0.260) question?

Stock #

R3087 (G1)

Quality Score

225

Status

Validated

Chromosome

Chromosomal Location

47893360-47894545 bp(+) (GRCm39)

Type of Mutation

exon

DNA Base Change (assembly)

A to G at 47894098 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Ref Sequence

ENSEMBL: ENSMUSP00000085634 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000088296]

AlphaFold

no structure available at present

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000088296

SMART Domains

Protein: ENSMUSP00000085634
Gene: ENSMUSG00000067716

Domain	Start	End	E-Value	Type
Pfam:Peptidase_C48	67	246	1e-43	PFAM

Meta Mutation Damage Score

0.8923

Coding Region Coverage

1x: 99.1%
3x: 98.5%
10x: 97.1%
20x: 94.6%

Validation Efficiency

97% (29/30)

Allele List at MGI

Other mutations in this stock

Total: 28 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Aknad1	C	T	3: 108,664,179 (GRCm39)	Q381*	probably null	Het
Arhgef39	C	T	4: 43,497,581 (GRCm39)		probably null	Het
Cblif	A	T	19: 11,737,737 (GRCm39)	K383*	probably null	Het
Ccdc85a	G	T	11: 28,342,857 (GRCm39)	C113*	probably null	Het
Cdc16	T	C	8: 13,809,004 (GRCm39)	Y19H	probably damaging	Het
Ces2e	T	A	8: 105,657,347 (GRCm39)	M289K	probably benign	Het
Cyp2u1	G	A	3: 131,096,676 (GRCm39)	A34V	probably benign	Het
Dkk2	A	C	3: 131,791,900 (GRCm39)	N36T	probably damaging	Het
Fam222a	A	G	5: 114,750,015 (GRCm39)	S404G	probably damaging	Het
Fbll1	A	T	11: 35,689,017 (GRCm39)	V82E	probably damaging	Het
Flt3	A	G	5: 147,284,856 (GRCm39)	S754P	probably benign	Het
Fmo5	T	C	3: 97,549,011 (GRCm39)	W220R	probably damaging	Het
Gmeb2	G	T	2: 180,897,433 (GRCm39)		probably benign	Het
Ifi44l	T	C	3: 151,468,494 (GRCm39)	H12R	unknown	Het
Itsn2	T	C	12: 4,716,303 (GRCm39)	Y1021H	probably damaging	Het
Map4	T	C	9: 109,882,257 (GRCm39)	S374P	possibly damaging	Het
Map4k4	A	T	1: 40,060,242 (GRCm39)		probably null	Het
Mast4	G	T	13: 102,990,434 (GRCm39)		probably benign	Het
Mdfic	T	A	6: 15,799,668 (GRCm39)	L265H	probably damaging	Het
Pabpc2	A	G	18: 39,907,319 (GRCm39)	I195V	probably benign	Het
Pramel25	A	G	4: 143,520,416 (GRCm39)	D56G	probably benign	Het
Prdm1	T	C	10: 44,322,823 (GRCm39)	Y224C	probably damaging	Het
Spidr	T	C	16: 15,786,483 (GRCm39)	Y420C	probably damaging	Het
Tlr6	A	T	5: 65,111,668 (GRCm39)	M413K	probably damaging	Het
Ttn	T	A	2: 76,585,168 (GRCm39)	I22042F	probably damaging	Het
Vmn1r11	A	C	6: 57,114,691 (GRCm39)	K81N	possibly damaging	Het
Vmn2r107	G	A	17: 20,580,607 (GRCm39)	E515K	probably benign	Het
Vstm4	T	C	14: 32,614,592 (GRCm39)	V178A	possibly damaging	Het

Other mutations in Gm7275

Allele	Source	Chr	Coord	Type	Predicted Effect
IGL01072:Gm7275	APN	16	47,894,519 (GRCm39)	exon	noncoding transcript
IGL01603:Gm7275	APN	16	47,893,942 (GRCm39)	exon	noncoding transcript
IGL01939:Gm7275	APN	16	47,893,946 (GRCm39)	exon	noncoding transcript
IGL02269:Gm7275	APN	16	47,894,185 (GRCm39)	exon	noncoding transcript
IGL02403:Gm7275	APN	16	47,893,991 (GRCm39)	exon	noncoding transcript
R0332:Gm7275	UTSW	16	47,894,132 (GRCm39)	exon	noncoding transcript
R1162:Gm7275	UTSW	16	47,894,395 (GRCm39)	exon	noncoding transcript
R1743:Gm7275	UTSW	16	47,894,120 (GRCm39)	exon	noncoding transcript
R4590:Gm7275	UTSW	16	47,893,982 (GRCm39)	exon	noncoding transcript
R5617:Gm7275	UTSW	16	47,894,527 (GRCm39)	exon	noncoding transcript
R5910:Gm7275	UTSW	16	47,893,826 (GRCm39)	exon	noncoding transcript

Predicted Primers

PCR Primer
(F):5'- GAATGCATTGGGTCCAGGAC -3'
(R):5'- CAATGCTCCTGCGTGTCTTG -3'

Sequencing Primer
(F):5'- GTCCAGGACCCCAAGAGGAAATC -3'
(R):5'- GGTCTCACAGATAAACTTGCCTG -3'

Posted On

2015-02-05