Incidental Mutation 'R3155:4933407L21Rik'
ID263441
Institutional Source Beutler Lab
Gene Symbol 4933407L21Rik
Ensembl Gene ENSMUSG00000026224
Gene NameRIKEN cDNA 4933407L21 gene
Synonyms
MMRRC Submission 040606-MU
Accession Numbers
Is this an essential gene? Probably non essential (E-score: 0.061) question?
Stock #R3155 (G1)
Quality Score225
Status Validated
Chromosome1
Chromosomal Location85928483-85940624 bp(+) (GRCm38)
Type of Mutationintron
DNA Base Change (assembly) T to C at 85931383 bp
ZygosityHeterozygous
Amino Acid Change
Ref Sequence ENSEMBL: ENSMUSP00000116804 (fasta)
Predicted Effect unknown
Transcript: ENSMUST00000027426
AA Change: I85T
Predicted Effect probably benign
Transcript: ENSMUST00000129392
Predicted Effect noncoding transcript
Transcript: ENSMUST00000188949
Predicted Effect noncoding transcript
Transcript: ENSMUST00000190367
Meta Mutation Damage Score 0.0608 question?
Coding Region Coverage
  • 1x: 99.2%
  • 3x: 98.6%
  • 10x: 97.4%
  • 20x: 95.5%
Validation Efficiency 100% (39/39)
Allele List at MGI
Other mutations in this stock
Total: 39 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
Aco1 T C 4: 40,182,915 V487A probably damaging Het
Adh1 A G 3: 138,280,489 E79G probably damaging Het
Aebp1 A G 11: 5,871,425 N608S probably benign Het
Ahctf1 G A 1: 179,755,583 R43C probably damaging Het
Ahnak A T 19: 9,010,177 I2942L possibly damaging Het
Anxa9 A T 3: 95,302,405 D134E probably benign Het
Ccdc14 A G 16: 34,723,852 D860G probably damaging Het
Cdhr3 T A 12: 33,049,153 I480F possibly damaging Het
Cldn34a C T X: 152,563,844 H171Y probably benign Het
Cyp2d9 T A 15: 82,452,642 probably null Het
Dmbt1 T A 7: 131,050,157 Y376* probably null Het
Fancm T C 12: 65,116,421 I1453T probably benign Het
Fbxw11 A G 11: 32,739,244 I456V possibly damaging Het
Fut2 A T 7: 45,650,667 L227Q probably damaging Het
Gbp5 T C 3: 142,503,127 probably null Het
Glrp1 C A 1: 88,503,254 Q131H unknown Het
Gm6871 T C 7: 41,573,655 N3S probably benign Het
H2-Eb1 C A 17: 34,314,374 T190K probably damaging Het
Kdr T A 5: 75,968,405 I194F probably benign Het
Klhdc7a A G 4: 139,967,189 V149A probably benign Het
Lrit3 A G 3: 129,791,395 F238S probably benign Het
Map10 A T 8: 125,671,574 I569F possibly damaging Het
Myh6 A G 14: 54,944,668 I1761T probably damaging Het
Npc1l1 A C 11: 6,221,840 D874E probably benign Het
Olfr726 T C 14: 50,084,525 D52G probably benign Het
Olfr895 T A 9: 38,268,540 M1K probably null Het
Pawr A G 10: 108,409,509 T193A probably benign Het
Ppp2r3a T C 9: 101,212,360 K255E possibly damaging Het
Rbp3 A T 14: 33,957,114 K1006N probably damaging Het
Rif1 GCCACCA GCCA 2: 52,110,324 probably benign Het
Rin2 A G 2: 145,860,851 K489R probably benign Het
Rlf A G 4: 121,149,332 V817A probably damaging Het
Rusc1 T C 3: 89,091,731 D248G probably benign Het
Slc15a4 A G 5: 127,604,536 probably null Het
Stk4 T A 2: 164,151,743 M98K probably benign Het
Taf15 T A 11: 83,502,773 H307Q probably benign Het
Urgcp A T 11: 5,716,327 F670L probably damaging Het
Vmn2r76 T C 7: 86,225,751 T673A probably damaging Het
Zfp324 G A 7: 12,968,890 M60I probably damaging Het
Other mutations in 4933407L21Rik
AlleleSourceChrCoordTypePredicted EffectPPH Score
R0308:4933407L21Rik UTSW 1 85931286 intron probably benign
R0458:4933407L21Rik UTSW 1 85929026 missense unknown
R3156:4933407L21Rik UTSW 1 85931383 intron probably benign
R3886:4933407L21Rik UTSW 1 85940551 splice site probably null
R3887:4933407L21Rik UTSW 1 85940551 splice site probably null
R3888:4933407L21Rik UTSW 1 85940551 splice site probably null
R3889:4933407L21Rik UTSW 1 85940551 splice site probably null
R4743:4933407L21Rik UTSW 1 85931251 intron probably benign
R4955:4933407L21Rik UTSW 1 85931287 intron probably benign
R5745:4933407L21Rik UTSW 1 85931274 splice site probably null
R7429:4933407L21Rik UTSW 1 85931307 missense unknown
Predicted Primers PCR Primer
(F):5'- TTCCTGGTAACCGGTGCATG -3'
(R):5'- ACACAAAGGTAGCCTGTTTGC -3'

Sequencing Primer
(F):5'- AACCGGTGCATGTGGGTCTATC -3'
(R):5'- AAAGGTAGCCTGTTTGCCTCAC -3'
Posted On2015-02-05