Incidental Mutation 'R3110:Nlrp9a'
| ID |
263824 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Nlrp9a
|
| Ensembl Gene |
ENSMUSG00000054102 |
| Gene Name |
NLR family, pyrin domain containing 9A |
| Synonyms |
Nalp9a, Nalp-theta, D7Ertd565e |
| MMRRC Submission |
040584-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.060)
|
| Stock # |
R3110 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
|
| Chromosome |
7 |
| Chromosomal Location |
26234448-26273573 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to C
at 26257297 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Valine to Alanine
at position 305
(V305A)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000113318
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000071780]
[ENSMUST00000108387]
[ENSMUST00000117252]
[ENSMUST00000122040]
[ENSMUST00000153452]
|
| AlphaFold |
no structure available at present |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000071780
AA Change: V305A
PolyPhen 2
Score 0.078 (Sensitivity: 0.93; Specificity: 0.85)
|
| SMART Domains |
Protein: ENSMUSP00000071685
Gene: ENSMUSG00000054102
AA Change: V305A
| Domain | Start | End | E-Value | Type |
|---|
|
PYRIN
|
5 |
87 |
1.07e-25 |
SMART |
|
Pfam:NACHT
|
143 |
311 |
1e-32 |
PFAM |
|
LRR
|
637 |
664 |
1.42e0 |
SMART |
|
LRR
|
693 |
720 |
2.32e-1 |
SMART |
|
LRR
|
722 |
749 |
3e0 |
SMART |
|
LRR
|
750 |
777 |
1.12e-3 |
SMART |
|
LRR
|
779 |
806 |
2.17e0 |
SMART |
|
LRR
|
807 |
834 |
2.27e-4 |
SMART |
|
LRR
|
836 |
863 |
2.02e2 |
SMART |
|
LRR
|
864 |
891 |
6.24e1 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000108387
AA Change: V305A
PolyPhen 2
Score 0.078 (Sensitivity: 0.93; Specificity: 0.85)
|
| SMART Domains |
Protein: ENSMUSP00000104024
Gene: ENSMUSG00000054102
AA Change: V305A
| Domain | Start | End | E-Value | Type |
|---|
|
PYRIN
|
5 |
87 |
1.07e-25 |
SMART |
|
Pfam:NACHT
|
143 |
311 |
7.7e-33 |
PFAM |
|
LRR
|
631 |
658 |
1.42e0 |
SMART |
|
LRR
|
692 |
719 |
1.42e0 |
SMART |
|
LRR
|
748 |
775 |
2.32e-1 |
SMART |
|
LRR
|
777 |
804 |
3e0 |
SMART |
|
LRR
|
805 |
832 |
1.12e-3 |
SMART |
|
LRR
|
834 |
861 |
2.17e0 |
SMART |
|
LRR
|
862 |
889 |
2.27e-4 |
SMART |
|
LRR
|
891 |
918 |
2.02e2 |
SMART |
|
LRR
|
919 |
946 |
6.24e1 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000117252
AA Change: V305A
PolyPhen 2
Score 0.006 (Sensitivity: 0.97; Specificity: 0.75)
|
| SMART Domains |
Protein: ENSMUSP00000112398
Gene: ENSMUSG00000054102
AA Change: V305A
| Domain | Start | End | E-Value | Type |
|---|
|
PYRIN
|
5 |
87 |
1.07e-25 |
SMART |
|
Pfam:NACHT
|
143 |
311 |
8.8e-34 |
PFAM |
|
LRR
|
637 |
664 |
1.42e0 |
SMART |
|
Blast:LRR
|
666 |
692 |
1e-5 |
BLAST |
|
LRR
|
693 |
720 |
2.32e-1 |
SMART |
|
LRR
|
722 |
749 |
3e0 |
SMART |
|
LRR
|
750 |
777 |
1.12e-3 |
SMART |
|
LRR
|
779 |
806 |
2.39e0 |
SMART |
|
LRR
|
807 |
834 |
6.24e1 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000122040
AA Change: V305A
PolyPhen 2
Score 0.078 (Sensitivity: 0.93; Specificity: 0.85)
|
| SMART Domains |
Protein: ENSMUSP00000113318
Gene: ENSMUSG00000054102
AA Change: V305A
| Domain | Start | End | E-Value | Type |
|---|
|
PYRIN
|
5 |
87 |
1.07e-25 |
SMART |
|
Pfam:NACHT
|
143 |
311 |
1e-32 |
PFAM |
|
LRR
|
637 |
664 |
1.42e0 |
SMART |
|
LRR
|
693 |
720 |
2.32e-1 |
SMART |
|
LRR
|
722 |
749 |
3e0 |
SMART |
|
LRR
|
750 |
777 |
1.12e-3 |
SMART |
|
LRR
|
779 |
806 |
2.17e0 |
SMART |
|
LRR
|
807 |
834 |
2.27e-4 |
SMART |
|
LRR
|
836 |
863 |
2.02e2 |
SMART |
|
LRR
|
864 |
891 |
6.24e1 |
SMART |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000143149
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000153452
AA Change: V216A
PolyPhen 2
Score 0.017 (Sensitivity: 0.95; Specificity: 0.80)
|
| SMART Domains |
Protein: ENSMUSP00000120498
Gene: ENSMUSG00000054102
AA Change: V216A
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:NACHT
|
54 |
222 |
6.9e-33 |
PFAM |
|
LRR
|
542 |
569 |
1.42e0 |
SMART |
|
LRR
|
603 |
630 |
1.42e0 |
SMART |
|
Blast:LRR
|
632 |
657 |
1e-5 |
BLAST |
|
LRR
|
659 |
686 |
2.32e-1 |
SMART |
|
LRR
|
688 |
715 |
3e0 |
SMART |
|
LRR
|
716 |
743 |
1.12e-3 |
SMART |
|
| Meta Mutation Damage Score |
0.0898 |
| Coding Region Coverage |
- 1x: 99.2%
- 3x: 98.6%
- 10x: 97.2%
- 20x: 95.0%
|
| Validation Efficiency |
98% (51/52) |
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 77 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Abca6 |
T |
A |
11: 110,069,655 (GRCm39) |
K1554* |
probably null |
Het |
| Acads |
T |
C |
5: 115,255,757 (GRCm39) |
H26R |
probably benign |
Het |
| Acer1 |
G |
A |
17: 57,265,406 (GRCm39) |
T141I |
probably damaging |
Het |
| Adam15 |
C |
G |
3: 89,254,764 (GRCm39) |
V99L |
probably benign |
Het |
| Ankrd13b |
A |
G |
11: 77,368,331 (GRCm39) |
V97A |
possibly damaging |
Het |
| Anpep |
T |
C |
7: 79,491,720 (GRCm39) |
T94A |
probably benign |
Het |
| Atp1a3 |
T |
C |
7: 24,694,119 (GRCm39) |
N345S |
probably damaging |
Het |
| Btn1a1 |
T |
A |
13: 23,645,721 (GRCm39) |
N216I |
possibly damaging |
Het |
| Cacna1s |
G |
A |
1: 136,002,831 (GRCm39) |
W62* |
probably null |
Het |
| Ccdc141 |
C |
T |
2: 76,869,830 (GRCm39) |
V892I |
probably benign |
Het |
| Ccdc180 |
T |
A |
4: 45,900,470 (GRCm39) |
I278K |
possibly damaging |
Het |
| Cdc7 |
T |
G |
5: 107,122,564 (GRCm39) |
|
probably null |
Het |
| Cpb1 |
C |
T |
3: 20,319,521 (GRCm39) |
V188M |
probably damaging |
Het |
| Dock5 |
A |
G |
14: 68,095,371 (GRCm39) |
I101T |
possibly damaging |
Het |
| Dqx1 |
T |
C |
6: 83,035,953 (GRCm39) |
V95A |
probably damaging |
Het |
| Dvl1 |
T |
A |
4: 155,938,123 (GRCm39) |
D90E |
probably damaging |
Het |
| Ebf1 |
T |
A |
11: 44,534,225 (GRCm39) |
|
probably benign |
Het |
| Fam135b |
T |
C |
15: 71,335,879 (GRCm39) |
I438M |
probably benign |
Het |
| Fpr1 |
A |
T |
17: 18,096,897 (GRCm39) |
M364K |
probably benign |
Het |
| Gm9932 |
A |
T |
5: 100,346,794 (GRCm39) |
|
unknown |
Het |
| Gpat4 |
G |
A |
8: 23,670,171 (GRCm39) |
P286L |
probably damaging |
Het |
| Gpx7 |
C |
A |
4: 108,260,470 (GRCm39) |
V109F |
probably damaging |
Het |
| Grhl2 |
T |
C |
15: 37,336,591 (GRCm39) |
|
probably null |
Het |
| Grn |
A |
G |
11: 102,324,069 (GRCm39) |
T53A |
probably benign |
Het |
| H1f4 |
T |
C |
13: 23,805,829 (GRCm39) |
|
probably benign |
Het |
| H2-T9 |
T |
C |
17: 36,440,038 (GRCm39) |
Y32C |
probably damaging |
Het |
| Hmgxb3 |
T |
C |
18: 61,280,454 (GRCm39) |
N683S |
probably damaging |
Het |
| Iigp1 |
T |
C |
18: 60,523,983 (GRCm39) |
I367T |
probably benign |
Het |
| Itfg2 |
T |
C |
6: 128,388,632 (GRCm39) |
E285G |
probably damaging |
Het |
| Itgav |
T |
A |
2: 83,622,915 (GRCm39) |
C662* |
probably null |
Het |
| Jarid2 |
T |
A |
13: 45,059,752 (GRCm39) |
N661K |
probably damaging |
Het |
| Jmjd1c |
T |
A |
10: 67,075,863 (GRCm39) |
|
probably benign |
Het |
| Lipe |
T |
C |
7: 25,097,848 (GRCm39) |
T32A |
probably benign |
Het |
| Lrrk2 |
A |
G |
15: 91,698,898 (GRCm39) |
Y2475C |
probably benign |
Het |
| Mcc |
T |
C |
18: 44,582,330 (GRCm39) |
D607G |
probably damaging |
Het |
| Mip |
T |
A |
10: 128,061,875 (GRCm39) |
L42* |
probably null |
Het |
| Mlc1 |
A |
T |
15: 88,850,199 (GRCm39) |
D192E |
probably benign |
Het |
| Muc2 |
T |
C |
7: 141,299,225 (GRCm39) |
|
probably benign |
Het |
| Mybl1 |
T |
C |
1: 9,752,095 (GRCm39) |
D260G |
probably damaging |
Het |
| Ncln |
C |
T |
10: 81,323,519 (GRCm39) |
V51I |
probably benign |
Het |
| Nodal |
G |
A |
10: 61,260,276 (GRCm39) |
R309Q |
possibly damaging |
Het |
| Olr1 |
T |
C |
6: 129,476,881 (GRCm39) |
N128S |
possibly damaging |
Het |
| Or10ak14 |
A |
T |
4: 118,611,421 (GRCm39) |
F105I |
probably damaging |
Het |
| Or12j5 |
A |
G |
7: 140,083,832 (GRCm39) |
I180T |
probably damaging |
Het |
| Or14a256 |
T |
C |
7: 86,264,884 (GRCm39) |
Y323C |
probably benign |
Het |
| Orc1 |
T |
A |
4: 108,461,757 (GRCm39) |
C585S |
probably benign |
Het |
| Pcmtd2 |
A |
T |
2: 181,496,922 (GRCm39) |
I300F |
probably damaging |
Het |
| Phactr3 |
T |
A |
2: 177,920,810 (GRCm39) |
L180Q |
possibly damaging |
Het |
| Pigo |
T |
C |
4: 43,021,083 (GRCm39) |
T612A |
probably benign |
Het |
| Plch1 |
T |
A |
3: 63,616,952 (GRCm39) |
D766V |
probably damaging |
Het |
| Plekhh3 |
T |
C |
11: 101,054,973 (GRCm39) |
|
probably benign |
Het |
| Potefam1 |
T |
G |
2: 111,058,399 (GRCm39) |
L131F |
probably damaging |
Het |
| Ppp1r12b |
T |
A |
1: 134,800,570 (GRCm39) |
T547S |
probably damaging |
Het |
| Prkcb |
T |
A |
7: 122,116,079 (GRCm39) |
M186K |
probably damaging |
Het |
| Prpf3 |
A |
T |
3: 95,757,112 (GRCm39) |
|
probably benign |
Het |
| Psg23 |
T |
C |
7: 18,344,369 (GRCm39) |
D362G |
possibly damaging |
Het |
| Reg3a |
T |
C |
6: 78,358,114 (GRCm39) |
L15P |
probably damaging |
Het |
| Rsf1 |
ATGGCG |
ATGGCGACGGTGGCG |
7: 97,229,111 (GRCm39) |
|
probably benign |
Het |
| Scrib |
A |
T |
15: 75,941,223 (GRCm39) |
I5N |
probably damaging |
Het |
| Speg |
C |
T |
1: 75,399,326 (GRCm39) |
Q2005* |
probably null |
Het |
| Sppl3 |
A |
T |
5: 115,212,923 (GRCm39) |
S51C |
possibly damaging |
Het |
| Sspo |
A |
G |
6: 48,434,534 (GRCm39) |
T1009A |
probably damaging |
Het |
| Syce1l |
A |
G |
8: 114,381,579 (GRCm39) |
Q164R |
probably benign |
Het |
| Sympk |
T |
C |
7: 18,768,409 (GRCm39) |
V126A |
possibly damaging |
Het |
| Tas2r110 |
T |
A |
6: 132,844,987 (GRCm39) |
I6K |
unknown |
Het |
| Tas2r120 |
A |
T |
6: 132,634,731 (GRCm39) |
H271L |
probably damaging |
Het |
| Tlcd3a |
A |
G |
11: 76,093,057 (GRCm39) |
D33G |
probably benign |
Het |
| Tnn |
T |
A |
1: 159,943,856 (GRCm39) |
T986S |
possibly damaging |
Het |
| Trim5 |
T |
C |
7: 103,928,845 (GRCm39) |
H32R |
probably damaging |
Het |
| Ttc13 |
A |
G |
8: 125,410,573 (GRCm39) |
I360T |
possibly damaging |
Het |
| Uaca |
A |
G |
9: 60,778,781 (GRCm39) |
E1054G |
probably damaging |
Het |
| Usp16 |
T |
A |
16: 87,268,736 (GRCm39) |
|
probably null |
Het |
| Wee1 |
T |
A |
7: 109,730,043 (GRCm39) |
S382R |
probably damaging |
Het |
| Wnt11 |
T |
C |
7: 98,495,771 (GRCm39) |
S92P |
probably damaging |
Het |
| Zfp1004 |
C |
G |
2: 150,034,141 (GRCm39) |
P185R |
probably damaging |
Het |
| Zfp786 |
A |
G |
6: 47,797,160 (GRCm39) |
C593R |
probably damaging |
Het |
| Zfp879 |
T |
G |
11: 50,723,989 (GRCm39) |
I283L |
possibly damaging |
Het |
|
| Other mutations in Nlrp9a |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00659:Nlrp9a
|
APN |
7 |
26,257,050 (GRCm39) |
missense |
probably benign |
0.22 |
|
IGL00895:Nlrp9a
|
APN |
7 |
26,258,103 (GRCm39) |
missense |
probably benign |
|
|
IGL01081:Nlrp9a
|
APN |
7 |
26,257,519 (GRCm39) |
missense |
possibly damaging |
0.51 |
|
IGL01148:Nlrp9a
|
APN |
7 |
26,257,006 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01368:Nlrp9a
|
APN |
7 |
26,257,299 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01914:Nlrp9a
|
APN |
7 |
26,256,689 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL01952:Nlrp9a
|
APN |
7 |
26,257,444 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL02245:Nlrp9a
|
APN |
7 |
26,257,318 (GRCm39) |
missense |
probably benign |
0.02 |
|
IGL02449:Nlrp9a
|
APN |
7 |
26,264,396 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL02702:Nlrp9a
|
APN |
7 |
26,264,381 (GRCm39) |
missense |
possibly damaging |
0.67 |
|
IGL02944:Nlrp9a
|
APN |
7 |
26,258,076 (GRCm39) |
missense |
probably benign |
0.28 |
|
IGL03183:Nlrp9a
|
APN |
7 |
26,256,882 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0005:Nlrp9a
|
UTSW |
7 |
26,273,213 (GRCm39) |
splice site |
probably benign |
|
|
R0007:Nlrp9a
|
UTSW |
7 |
26,250,515 (GRCm39) |
intron |
probably benign |
|
|
R0007:Nlrp9a
|
UTSW |
7 |
26,250,515 (GRCm39) |
intron |
probably benign |
|
|
R0013:Nlrp9a
|
UTSW |
7 |
26,270,650 (GRCm39) |
splice site |
probably null |
|
|
R0086:Nlrp9a
|
UTSW |
7 |
26,257,972 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R0659:Nlrp9a
|
UTSW |
7 |
26,256,703 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1126:Nlrp9a
|
UTSW |
7 |
26,260,166 (GRCm39) |
missense |
probably benign |
0.12 |
|
R1500:Nlrp9a
|
UTSW |
7 |
26,267,316 (GRCm39) |
missense |
probably benign |
0.01 |
|
R1585:Nlrp9a
|
UTSW |
7 |
26,258,093 (GRCm39) |
missense |
probably benign |
0.41 |
|
R1594:Nlrp9a
|
UTSW |
7 |
26,269,932 (GRCm39) |
nonsense |
probably null |
|
|
R1968:Nlrp9a
|
UTSW |
7 |
26,264,366 (GRCm39) |
missense |
probably benign |
0.23 |
|
R1989:Nlrp9a
|
UTSW |
7 |
26,273,338 (GRCm39) |
missense |
probably benign |
0.24 |
|
R2057:Nlrp9a
|
UTSW |
7 |
26,256,787 (GRCm39) |
missense |
possibly damaging |
0.55 |
|
R2058:Nlrp9a
|
UTSW |
7 |
26,256,787 (GRCm39) |
missense |
possibly damaging |
0.55 |
|
R2059:Nlrp9a
|
UTSW |
7 |
26,256,787 (GRCm39) |
missense |
possibly damaging |
0.55 |
|
R2188:Nlrp9a
|
UTSW |
7 |
26,264,354 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2318:Nlrp9a
|
UTSW |
7 |
26,273,277 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R3112:Nlrp9a
|
UTSW |
7 |
26,257,297 (GRCm39) |
missense |
probably benign |
0.08 |
|
R3237:Nlrp9a
|
UTSW |
7 |
26,270,810 (GRCm39) |
nonsense |
probably null |
|
|
R3545:Nlrp9a
|
UTSW |
7 |
26,256,757 (GRCm39) |
missense |
probably benign |
0.03 |
|
R3805:Nlrp9a
|
UTSW |
7 |
26,264,277 (GRCm39) |
nonsense |
probably null |
|
|
R4005:Nlrp9a
|
UTSW |
7 |
26,257,975 (GRCm39) |
missense |
probably benign |
0.02 |
|
R4057:Nlrp9a
|
UTSW |
7 |
26,270,071 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4529:Nlrp9a
|
UTSW |
7 |
26,270,832 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4756:Nlrp9a
|
UTSW |
7 |
26,256,866 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4908:Nlrp9a
|
UTSW |
7 |
26,250,369 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4972:Nlrp9a
|
UTSW |
7 |
26,269,964 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4992:Nlrp9a
|
UTSW |
7 |
26,256,811 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5042:Nlrp9a
|
UTSW |
7 |
26,270,703 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5224:Nlrp9a
|
UTSW |
7 |
26,256,717 (GRCm39) |
missense |
probably benign |
0.43 |
|
R5449:Nlrp9a
|
UTSW |
7 |
26,257,254 (GRCm39) |
missense |
probably benign |
0.04 |
|
R5644:Nlrp9a
|
UTSW |
7 |
26,257,993 (GRCm39) |
missense |
possibly damaging |
0.51 |
|
R5734:Nlrp9a
|
UTSW |
7 |
26,270,065 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5905:Nlrp9a
|
UTSW |
7 |
26,257,762 (GRCm39) |
missense |
probably benign |
0.02 |
|
R5978:Nlrp9a
|
UTSW |
7 |
26,256,703 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6028:Nlrp9a
|
UTSW |
7 |
26,257,762 (GRCm39) |
missense |
probably benign |
0.02 |
|
R6066:Nlrp9a
|
UTSW |
7 |
26,257,510 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6082:Nlrp9a
|
UTSW |
7 |
26,267,402 (GRCm39) |
missense |
probably benign |
0.41 |
|
R6171:Nlrp9a
|
UTSW |
7 |
26,258,188 (GRCm39) |
missense |
possibly damaging |
0.71 |
|
R6352:Nlrp9a
|
UTSW |
7 |
26,257,051 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6490:Nlrp9a
|
UTSW |
7 |
26,250,311 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6540:Nlrp9a
|
UTSW |
7 |
26,256,817 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
R7039:Nlrp9a
|
UTSW |
7 |
26,267,367 (GRCm39) |
missense |
probably benign |
0.03 |
|
R7151:Nlrp9a
|
UTSW |
7 |
26,256,672 (GRCm39) |
nonsense |
probably null |
|
|
R7173:Nlrp9a
|
UTSW |
7 |
26,257,603 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7214:Nlrp9a
|
UTSW |
7 |
26,250,463 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R7226:Nlrp9a
|
UTSW |
7 |
26,258,149 (GRCm39) |
missense |
probably benign |
0.02 |
|
R7250:Nlrp9a
|
UTSW |
7 |
26,258,143 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
R7293:Nlrp9a
|
UTSW |
7 |
26,270,694 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7492:Nlrp9a
|
UTSW |
7 |
26,257,081 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7586:Nlrp9a
|
UTSW |
7 |
26,256,721 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R7844:Nlrp9a
|
UTSW |
7 |
26,262,006 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
R8073:Nlrp9a
|
UTSW |
7 |
26,260,260 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R8136:Nlrp9a
|
UTSW |
7 |
26,256,678 (GRCm39) |
missense |
probably benign |
0.34 |
|
R8400:Nlrp9a
|
UTSW |
7 |
26,264,431 (GRCm39) |
missense |
probably benign |
0.02 |
|
R8415:Nlrp9a
|
UTSW |
7 |
26,256,925 (GRCm39) |
missense |
probably benign |
|
|
R8774:Nlrp9a
|
UTSW |
7 |
26,257,984 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R8774-TAIL:Nlrp9a
|
UTSW |
7 |
26,257,984 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R8882:Nlrp9a
|
UTSW |
7 |
26,257,703 (GRCm39) |
nonsense |
probably null |
|
|
R9023:Nlrp9a
|
UTSW |
7 |
26,273,291 (GRCm39) |
missense |
possibly damaging |
0.62 |
|
R9031:Nlrp9a
|
UTSW |
7 |
26,257,698 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9063:Nlrp9a
|
UTSW |
7 |
26,273,291 (GRCm39) |
missense |
possibly damaging |
0.62 |
|
R9090:Nlrp9a
|
UTSW |
7 |
26,261,944 (GRCm39) |
missense |
probably benign |
|
|
R9196:Nlrp9a
|
UTSW |
7 |
26,258,158 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9206:Nlrp9a
|
UTSW |
7 |
26,257,656 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R9265:Nlrp9a
|
UTSW |
7 |
26,258,038 (GRCm39) |
missense |
possibly damaging |
0.67 |
|
R9271:Nlrp9a
|
UTSW |
7 |
26,261,944 (GRCm39) |
missense |
probably benign |
|
|
R9384:Nlrp9a
|
UTSW |
7 |
26,258,158 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9402:Nlrp9a
|
UTSW |
7 |
26,270,030 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
R9424:Nlrp9a
|
UTSW |
7 |
26,260,178 (GRCm39) |
missense |
probably benign |
0.13 |
|
R9620:Nlrp9a
|
UTSW |
7 |
26,250,469 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9660:Nlrp9a
|
UTSW |
7 |
26,256,915 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9696:Nlrp9a
|
UTSW |
7 |
26,275,033 (GRCm39) |
missense |
unknown |
|
|
R9728:Nlrp9a
|
UTSW |
7 |
26,256,915 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9744:Nlrp9a
|
UTSW |
7 |
26,267,266 (GRCm39) |
missense |
probably benign |
0.07 |
|
R9794:Nlrp9a
|
UTSW |
7 |
26,264,302 (GRCm39) |
missense |
probably benign |
0.03 |
|
Z1176:Nlrp9a
|
UTSW |
7 |
26,257,654 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1177:Nlrp9a
|
UTSW |
7 |
26,256,881 (GRCm39) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- GCTGCCAATACAAATTGTCTTGAG -3'
(R):5'- ACGGGCCCTGTTCTGTTTAG -3'
Sequencing Primer
(F):5'- ACAAATTGTCTTGAGTAGTTTGCTAC -3'
(R):5'- CCTGGCATATGTTGATTTAAATGCGC -3'
|
| Posted On |
2015-02-05 |
Incidental Mutation