Mutagenetix > Incidental Mutation

Incidental Mutation 'IGL00487:Dusp23'

26569

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Dusp23

Ensembl Gene

ENSMUSG00000026544

Gene Name

dual specificity phosphatase 23

Synonyms

1300005N15Rik, Ldp-3

Accession Numbers

Essential gene?

Probably non essential (E-score: 0.067) question?

Stock #

IGL00487

Quality Score

Status

Chromosome

Chromosomal Location

172458336-172460504 bp(-) (GRCm39)

Type of Mutation

utr 3 prime

DNA Base Change (assembly)

T to C at 172459199 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Ref Sequence

ENSEMBL: ENSMUSP00000027826 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000027826]

AlphaFold

Q6NT99

Predicted Effect

probably benign
Transcript: ENSMUST00000027826

SMART Domains

Protein: ENSMUSP00000027826
Gene: ENSMUSG00000026544

Domain	Start	End	E-Value	Type
Pfam:DSPc	26	148	1e-14	PFAM
Pfam:Y_phosphatase	36	147	7.6e-10	PFAM
Pfam:PTPlike_phytase	48	112	3.1e-14	PFAM

Coding Region Coverage

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 15 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Abca5	T	A	11: 110,200,276 (GRCm39)		probably null	Het
Cfap251	T	G	5: 123,412,240 (GRCm39)	I84S	probably damaging	Het
Invs	C	T	4: 48,407,689 (GRCm39)	Q555*	probably null	Het
Mak16	T	C	8: 31,656,778 (GRCm39)	N9D	probably benign	Het
Mrps7	T	C	11: 115,495,684 (GRCm39)	I74T	possibly damaging	Het
Nlrp4a	T	G	7: 26,149,410 (GRCm39)	V339G	possibly damaging	Het
Nucb1	A	G	7: 45,151,075 (GRCm39)	L102P	probably damaging	Het
Pdp2	T	C	8: 105,320,829 (GRCm39)	M226T	probably benign	Het
Pik3r2	T	C	8: 71,223,073 (GRCm39)	D449G	probably damaging	Het
Rnf157	G	A	11: 116,253,181 (GRCm39)	P76S	probably benign	Het
Senp6	C	A	9: 80,021,120 (GRCm39)	Q267K	probably damaging	Het
Slc9a2	A	G	1: 40,781,818 (GRCm39)	E349G	probably damaging	Het
Snx14	G	T	9: 88,284,243 (GRCm39)	S475Y	probably damaging	Het
Vmn1r180	A	T	7: 23,651,948 (GRCm39)	H37L	probably benign	Het
Xrn1	A	T	9: 95,921,002 (GRCm39)	H1371L	probably benign	Het

Other mutations in Dusp23

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
R4571:Dusp23	UTSW	1	172,460,181 (GRCm39)	critical splice donor site	probably null
R6991:Dusp23	UTSW	1	172,459,224 (GRCm39)	missense	probably benign	0.00
R7048:Dusp23	UTSW	1	172,459,253 (GRCm39)	nonsense	probably null
R8869:Dusp23	UTSW	1	172,460,293 (GRCm39)	missense	possibly damaging	0.92
R9043:Dusp23	UTSW	1	172,460,184 (GRCm39)	missense	probably null	0.71

Posted On

2013-04-17