Mutagenetix > Incidental Mutation

Incidental Mutation 'R3697:Gm16380'

269858

Institutional Source

Beutler Lab

Gene Symbol

Gm16380

Ensembl Gene

ENSMUSG00000059830

Gene Name

predicted pseudogene 16380

Synonyms

MMRRC Submission

040691-MU

Accession Numbers

Essential gene?

Probably non essential (E-score: 0.162) question?

Stock #

R3697 (G1)

Quality Score

225

Status

Not validated

Chromosome

Chromosomal Location

53791368-53791845 bp(+) (GRCm39)

Type of Mutation

exon

DNA Base Change (assembly)

A to G at 53791736 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Gene Model

predicted gene model for transcript(s):

AlphaFold

no structure available at present

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000077997

SMART Domains

Protein: ENSMUSP00000129245
Gene: ENSMUSG00000059830

Domain	Start	End	E-Value	Type
Pfam:Siva	1	152	6.6e-65	PFAM

Coding Region Coverage

1x: 99.1%
3x: 98.5%
10x: 97.1%
20x: 94.4%

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 28 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Aldh4a1	A	G	4: 139,369,562 (GRCm39)	H371R	possibly damaging	Het
Arhgef4	A	G	1: 34,761,521 (GRCm39)	D259G	unknown	Het
Bckdk	C	A	7: 127,504,590 (GRCm39)	R105S	probably damaging	Het
Clcn3	T	C	8: 61,366,157 (GRCm39)	D805G	probably benign	Het
Cnmd	C	A	14: 79,875,421 (GRCm39)	R333L	probably damaging	Het
Col4a4	A	T	1: 82,518,958 (GRCm39)	I79N	unknown	Het
Emc1	T	G	4: 139,092,697 (GRCm39)	S546A	possibly damaging	Het
Ermard	T	C	17: 15,273,638 (GRCm39)	S408P	probably benign	Het
Gls	C	T	1: 52,238,923 (GRCm39)	M364I	possibly damaging	Het
Il12a	TCAC	TC	3: 68,605,320 (GRCm39)		probably null	Het
Il6st	T	G	13: 112,640,916 (GRCm39)	D897E	probably benign	Het
Itga3	T	C	11: 94,953,551 (GRCm39)	T233A	probably benign	Het
Kcnd3	C	T	3: 105,566,082 (GRCm39)	A421V	probably damaging	Het
Lemd3	CCCTCCTCCTCCTCCTCCTCC	CCCTCCTCCTCCTCCTCC	10: 120,814,432 (GRCm39)		probably benign	Het
Miga1	T	C	3: 152,028,073 (GRCm39)	N152S	probably damaging	Het
Nckipsd	G	A	9: 108,688,320 (GRCm39)	G83S	probably damaging	Het
Nedd4	T	C	9: 72,647,469 (GRCm39)	F728L	probably damaging	Het
Nid1	G	A	13: 13,661,344 (GRCm39)	C748Y	probably damaging	Het
Nop56	C	A	2: 130,119,507 (GRCm39)	N57K	probably damaging	Het
Nup205	A	G	6: 35,165,646 (GRCm39)	N197S	probably benign	Het
Pglyrp3	T	A	3: 91,935,481 (GRCm39)	C244S	probably damaging	Het
Rgs22	C	T	15: 36,100,038 (GRCm39)	V226I	probably benign	Het
Rtp3	T	A	9: 110,816,262 (GRCm39)	R96S	possibly damaging	Het
Serpinb8	A	T	1: 107,534,876 (GRCm39)	K316*	probably null	Het
Sp6	C	A	11: 96,912,580 (GRCm39)	P98T	possibly damaging	Het
Vmn1r15	A	T	6: 57,235,321 (GRCm39)	D63V	possibly damaging	Het
Vmn1r216	G	A	13: 23,283,849 (GRCm39)	W177*	probably null	Het
Zfp414	CAAACTCTTCCGA	CAAACTCTTCCGAAACTCTTCCGA	17: 33,849,551 (GRCm39)		probably null	Het

Other mutations in Gm16380

Allele	Source	Chr	Coord	Type	Predicted Effect
IGL02207:Gm16380	APN	9	53,791,823 (GRCm39)	exon	noncoding transcript
R0386:Gm16380	UTSW	9	53,791,727 (GRCm39)	exon	noncoding transcript
R0398:Gm16380	UTSW	9	53,791,453 (GRCm39)	exon	noncoding transcript
R0512:Gm16380	UTSW	9	53,791,529 (GRCm39)	exon	noncoding transcript
R1419:Gm16380	UTSW	9	53,791,471 (GRCm39)	exon	noncoding transcript
R2301:Gm16380	UTSW	9	53,791,484 (GRCm39)	exon	noncoding transcript
R5128:Gm16380	UTSW	9	53,791,397 (GRCm39)	exon	noncoding transcript

Predicted Primers

PCR Primer
(F):5'- ATTGTTCTGTGAACCACCTACG -3'
(R):5'- AGCGTGGACTTCTTTCAAAAGG -3'

Sequencing Primer
(F):5'- CTACGGGAGTCACTGAAGTCTG -3'
(R):5'- GGACTTCTTTCAAAAGGATCCCTGAG -3'

Posted On

2015-03-18