Mutagenetix > Incidental Mutation

Incidental Mutation 'IGL00886:Lzic'

27194

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Lzic

Ensembl Gene

ENSMUSG00000028990

Gene Name

leucine zipper and CTNNBIP1 domain containing

Synonyms

1810030J04Rik

Accession Numbers

Essential gene?

Probably non essential (E-score: 0.152) question?

Stock #

IGL00886

Quality Score

Status

Chromosome

Chromosomal Location

149569686-149581125 bp(+) (GRCm39)

Type of Mutation

critical splice donor site (2 bp from exon)

DNA Base Change (assembly)

T to C at 149577753 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Ref Sequence

ENSEMBL: ENSMUSP00000030842 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000030842]

AlphaFold

Q8K3C3

Predicted Effect

probably null
Transcript: ENSMUST00000030842

SMART Domains

Protein: ENSMUSP00000030842
Gene: ENSMUSG00000028990

Domain	Start	End	E-Value	Type
coiled coil region	2	63	N/A	INTRINSIC
Pfam:ICAT	113	188	5.7e-36	PFAM

Coding Region Coverage

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 37 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Abca9	C	T	11: 110,054,101 (GRCm39)	R67H	possibly damaging	Het
Ak4	G	T	4: 101,304,386 (GRCm39)	E59*	probably null	Het
Ano10	T	C	9: 122,100,390 (GRCm39)	N116S	probably benign	Het
Arid1b	T	A	17: 5,177,254 (GRCm39)	H658Q	probably damaging	Het
Atf2	G	A	2: 73,675,847 (GRCm39)	T208I	possibly damaging	Het
Bco1	T	C	8: 117,857,376 (GRCm39)	W448R	probably damaging	Het
Cel	A	T	2: 28,449,397 (GRCm39)	C277S	probably damaging	Het
Chd5	T	A	4: 152,444,156 (GRCm39)	D296E	probably benign	Het
Crygd	C	T	1: 65,101,250 (GRCm39)	R115Q	probably benign	Het
Fmo9	T	C	1: 166,507,714 (GRCm39)		probably null	Het
Gdpgp1	T	G	7: 79,889,100 (GRCm39)	L377R	probably damaging	Het
Gm26938	T	A	5: 139,812,091 (GRCm39)	D3V	probably damaging	Het
Gpld1	T	A	13: 25,146,336 (GRCm39)	Y193*	probably null	Het
Gtf2h4	T	C	17: 35,980,874 (GRCm39)	H265R	probably damaging	Het
Hadh	G	T	3: 131,043,465 (GRCm39)	T83K	probably benign	Het
Hao1	T	C	2: 134,365,079 (GRCm39)	M183V	probably benign	Het
Hnrnpm	C	A	17: 33,868,876 (GRCm39)	R517L	probably damaging	Het
Ift88	T	C	14: 57,715,525 (GRCm39)	Y523H	probably damaging	Het
Il23r	G	T	6: 67,450,874 (GRCm39)	Q202K	possibly damaging	Het
Iyd	T	C	10: 3,540,444 (GRCm38)	D50A	probably benign	Het
Katnal2	A	T	18: 77,090,450 (GRCm39)	L248Q	probably damaging	Het
Krtap26-1	A	T	16: 88,444,267 (GRCm39)	V118E	possibly damaging	Het
Meak7	T	C	8: 120,500,007 (GRCm39)		probably benign	Het
Mical2	T	A	7: 111,914,279 (GRCm39)	N316K	probably benign	Het
Ndufc2	T	A	7: 97,049,397 (GRCm39)	M1K	probably null	Het
Net1	A	G	13: 3,943,391 (GRCm39)		probably benign	Het
Or13g1	G	A	7: 85,956,259 (GRCm39)	L21F	probably damaging	Het
Pde1c	A	G	6: 56,150,659 (GRCm39)	Y287H	probably damaging	Het
Pitpnm1	T	C	19: 4,160,665 (GRCm39)		probably null	Het
Pla2r1	T	A	2: 60,254,668 (GRCm39)	E1300V	probably damaging	Het
Polr3g	T	C	13: 81,842,796 (GRCm39)	Y73C	probably damaging	Het
Ryr1	T	A	7: 28,723,654 (GRCm39)	E4137V	probably damaging	Het
Scrib	T	C	15: 75,920,643 (GRCm39)	D1425G	possibly damaging	Het
Slc25a12	A	G	2: 71,174,376 (GRCm39)	Y23H	possibly damaging	Het
Spef2	C	A	15: 9,663,181 (GRCm39)	G867W	probably damaging	Het
Strn3	A	T	12: 51,656,933 (GRCm39)	Y698N	probably damaging	Het
Ube3a	T	A	7: 58,934,485 (GRCm39)	F533I	probably damaging	Het

Other mutations in Lzic

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL01433:Lzic	APN	4	149,572,604 (GRCm39)	missense	probably benign	0.00
IGL02480:Lzic	APN	4	149,571,260 (GRCm39)	missense	probably damaging	1.00
R0097:Lzic	UTSW	4	149,572,533 (GRCm39)	missense	probably damaging	1.00
R0097:Lzic	UTSW	4	149,572,533 (GRCm39)	missense	probably damaging	1.00
R1345:Lzic	UTSW	4	149,571,308 (GRCm39)	missense	probably damaging	1.00
R2162:Lzic	UTSW	4	149,573,185 (GRCm39)	missense	probably null	0.01
R3831:Lzic	UTSW	4	149,573,185 (GRCm39)	missense	probably null	0.01
R4589:Lzic	UTSW	4	149,572,561 (GRCm39)	missense	probably damaging	0.98
R4929:Lzic	UTSW	4	149,572,585 (GRCm39)	splice site	probably null
R5837:Lzic	UTSW	4	149,570,457 (GRCm39)	critical splice donor site	probably null
R7126:Lzic	UTSW	4	149,573,132 (GRCm39)	missense	probably damaging	0.99
R8154:Lzic	UTSW	4	149,573,141 (GRCm39)	missense	probably damaging	1.00
R8316:Lzic	UTSW	4	149,572,527 (GRCm39)	missense	probably benign	0.03
R9632:Lzic	UTSW	4	149,573,141 (GRCm39)	missense	probably damaging	1.00
R9710:Lzic	UTSW	4	149,573,141 (GRCm39)	missense	probably damaging	1.00

Posted On

2013-04-17