Incidental Mutation 'IGL00948:Vmn1r19'
| ID |
27657 |
| Institutional Source |
Australian Phenomics Network
(link to record)
|
| Gene Symbol |
Vmn1r19
|
| Ensembl Gene |
ENSMUSG00000115799 |
| Gene Name |
vomeronasal 1 receptor 19 |
| Synonyms |
V1rc27 |
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.094)
|
| Stock # |
IGL00948
|
| Quality Score |
|
|
Status
|
|
| Chromosome |
6 |
| Chromosomal Location |
57381449-57382375 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to C
at 57382247 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Phenylalanine to Leucine
at position 267
(F267L)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000087264
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000089830]
|
| AlphaFold |
Q8R2C7 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000089830
AA Change: F267L
PolyPhen 2
Score 0.030 (Sensitivity: 0.95; Specificity: 0.82)
|
| SMART Domains |
Protein: ENSMUSP00000087264
Gene: ENSMUSG00000115799
AA Change: F267L
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:V1R
|
28 |
293 |
6.6e-58 |
PFAM |
|
| Coding Region Coverage |
|
| Validation Efficiency |
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 25 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Ccl2 |
A |
T |
11: 81,926,558 (GRCm39) |
Q24L |
possibly damaging |
Het |
| Cd33 |
G |
A |
7: 43,178,982 (GRCm39) |
|
probably benign |
Het |
| Cmya5 |
T |
C |
13: 93,227,544 (GRCm39) |
I2515V |
probably benign |
Het |
| Cntnap5b |
A |
G |
1: 100,069,082 (GRCm39) |
T101A |
probably benign |
Het |
| Cyp4a12a |
T |
A |
4: 115,159,159 (GRCm39) |
M143K |
probably damaging |
Het |
| Ephb4 |
C |
A |
5: 137,364,921 (GRCm39) |
S663R |
probably damaging |
Het |
| Gm4847 |
T |
C |
1: 166,457,907 (GRCm39) |
D482G |
probably benign |
Het |
| Gskip |
C |
A |
12: 105,665,103 (GRCm39) |
N47K |
probably damaging |
Het |
| Kmt2c |
T |
C |
5: 25,582,159 (GRCm39) |
Y473C |
probably benign |
Het |
| Lrrc7 |
T |
A |
3: 157,867,194 (GRCm39) |
N849I |
probably damaging |
Het |
| Magel2 |
T |
A |
7: 62,029,070 (GRCm39) |
V658E |
unknown |
Het |
| Nmral1 |
C |
T |
16: 4,534,270 (GRCm39) |
G57E |
probably damaging |
Het |
| Or6c211 |
A |
T |
10: 129,505,756 (GRCm39) |
L211I |
probably damaging |
Het |
| Or8b54 |
C |
T |
9: 38,687,108 (GRCm39) |
Q186* |
probably null |
Het |
| Padi3 |
C |
A |
4: 140,516,254 (GRCm39) |
R542L |
possibly damaging |
Het |
| Plrg1 |
T |
C |
3: 82,975,426 (GRCm39) |
V260A |
probably damaging |
Het |
| Prex2 |
A |
G |
1: 11,240,838 (GRCm39) |
H982R |
probably damaging |
Het |
| Rbm26 |
T |
A |
14: 105,387,779 (GRCm39) |
T448S |
probably damaging |
Het |
| Ryr1 |
C |
T |
7: 28,719,620 (GRCm39) |
M4262I |
possibly damaging |
Het |
| Slc41a3 |
A |
T |
6: 90,622,696 (GRCm39) |
D441V |
probably damaging |
Het |
| Slc7a2 |
A |
G |
8: 41,365,561 (GRCm39) |
E448G |
probably benign |
Het |
| Smtnl2 |
C |
A |
11: 72,302,067 (GRCm39) |
|
probably null |
Het |
| Tox3 |
G |
A |
8: 90,997,062 (GRCm39) |
P66L |
probably damaging |
Het |
| Vmn2r12 |
A |
G |
5: 109,245,541 (GRCm39) |
S64P |
possibly damaging |
Het |
| Zfp764 |
T |
C |
7: 127,004,376 (GRCm39) |
S252G |
possibly damaging |
Het |
|
| Other mutations in Vmn1r19 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL01287:Vmn1r19
|
APN |
6 |
57,382,179 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01516:Vmn1r19
|
APN |
6 |
57,381,857 (GRCm39) |
missense |
probably benign |
0.03 |
|
IGL01895:Vmn1r19
|
APN |
6 |
57,382,245 (GRCm39) |
missense |
probably benign |
0.02 |
|
IGL02676:Vmn1r19
|
APN |
6 |
57,382,025 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
IGL03040:Vmn1r19
|
APN |
6 |
57,382,347 (GRCm39) |
missense |
unknown |
|
|
IGL03087:Vmn1r19
|
APN |
6 |
57,381,476 (GRCm39) |
missense |
probably benign |
0.01 |
|
PIT4802001:Vmn1r19
|
UTSW |
6 |
57,382,037 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0319:Vmn1r19
|
UTSW |
6 |
57,381,600 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R1368:Vmn1r19
|
UTSW |
6 |
57,381,656 (GRCm39) |
missense |
probably benign |
0.01 |
|
R1997:Vmn1r19
|
UTSW |
6 |
57,382,033 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2920:Vmn1r19
|
UTSW |
6 |
57,381,909 (GRCm39) |
missense |
probably benign |
0.03 |
|
R3857:Vmn1r19
|
UTSW |
6 |
57,382,098 (GRCm39) |
missense |
possibly damaging |
0.68 |
|
R4090:Vmn1r19
|
UTSW |
6 |
57,381,720 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4547:Vmn1r19
|
UTSW |
6 |
57,381,774 (GRCm39) |
missense |
possibly damaging |
0.56 |
|
R4823:Vmn1r19
|
UTSW |
6 |
57,382,219 (GRCm39) |
nonsense |
probably null |
|
|
R4951:Vmn1r19
|
UTSW |
6 |
57,381,927 (GRCm39) |
missense |
probably benign |
0.36 |
|
R5077:Vmn1r19
|
UTSW |
6 |
57,382,026 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5459:Vmn1r19
|
UTSW |
6 |
57,381,475 (GRCm39) |
nonsense |
probably null |
|
|
R5625:Vmn1r19
|
UTSW |
6 |
57,382,281 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5690:Vmn1r19
|
UTSW |
6 |
57,381,780 (GRCm39) |
missense |
probably benign |
0.10 |
|
R5761:Vmn1r19
|
UTSW |
6 |
57,382,338 (GRCm39) |
missense |
unknown |
|
|
R6124:Vmn1r19
|
UTSW |
6 |
57,381,602 (GRCm39) |
missense |
probably benign |
0.02 |
|
R6373:Vmn1r19
|
UTSW |
6 |
57,382,317 (GRCm39) |
missense |
unknown |
|
|
R6476:Vmn1r19
|
UTSW |
6 |
57,381,578 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6938:Vmn1r19
|
UTSW |
6 |
57,381,992 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R7027:Vmn1r19
|
UTSW |
6 |
57,381,475 (GRCm39) |
nonsense |
probably null |
|
|
R7359:Vmn1r19
|
UTSW |
6 |
57,382,080 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7568:Vmn1r19
|
UTSW |
6 |
57,381,813 (GRCm39) |
missense |
possibly damaging |
0.69 |
|
R7893:Vmn1r19
|
UTSW |
6 |
57,381,664 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8481:Vmn1r19
|
UTSW |
6 |
57,381,932 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8487:Vmn1r19
|
UTSW |
6 |
57,382,166 (GRCm39) |
missense |
probably benign |
0.03 |
|
R8812:Vmn1r19
|
UTSW |
6 |
57,381,436 (GRCm39) |
start gained |
probably benign |
|
|
R8907:Vmn1r19
|
UTSW |
6 |
57,381,991 (GRCm39) |
missense |
probably benign |
|
|
R8976:Vmn1r19
|
UTSW |
6 |
57,381,719 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9277:Vmn1r19
|
UTSW |
6 |
57,382,322 (GRCm39) |
missense |
unknown |
|
|
| Posted On |
2013-04-17 |
Incidental Mutation