Incidental Mutation 'IGL00956:Clec4b2'
ID27675
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Clec4b2
Ensembl Gene ENSMUSG00000067767
Gene NameC-type lectin domain family 4, member b2
SynonymsF830043G12Rik, mDCAR1
Accession Numbers
Is this an essential gene? Probably non essential (E-score: 0.051) question?
Stock #IGL00956
Quality Score
Status
Chromosome6
Chromosomal Location123172893-123204671 bp(+) (GRCm38)
Type of Mutationnonsense
DNA Base Change (assembly) T to A at 123202151 bp
ZygosityHeterozygous
Amino Acid Change Tyrosine to Stop codon at position 137 (Y137*)
Ref Sequence ENSEMBL: ENSMUSP00000085802 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000088455]
Predicted Effect probably null
Transcript: ENSMUST00000088455
AA Change: Y137*
SMART Domains Protein: ENSMUSP00000085802
Gene: ENSMUSG00000067767
AA Change: Y137*

DomainStartEndE-ValueType
transmembrane domain 21 43 N/A INTRINSIC
CLECT 79 202 1.87e-33 SMART
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 20 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
Cdhr2 G T 13: 54,718,343 V319F probably damaging Het
Chac2 A G 11: 30,986,225 S8P probably damaging Het
Dbt G A 3: 116,546,114 G384S probably benign Het
Duox1 G T 2: 122,323,306 R370L probably benign Het
Gm21949 C A 3: 68,625,851 A255E probably damaging Het
Gm4951 A C 18: 60,246,190 T266P probably damaging Het
Hnrnpm C A 17: 33,649,902 R517L probably damaging Het
Kcnh7 G A 2: 62,777,639 R533C probably damaging Het
Nckap5 A C 1: 126,025,018 L1266V probably damaging Het
Opcml A G 9: 28,675,328 N121S possibly damaging Het
Rad54b T A 4: 11,597,833 N239K probably damaging Het
Rp1 T C 1: 4,352,212 D215G probably damaging Het
Scaf8 T C 17: 3,171,147 I303T unknown Het
Slc35f3 G A 8: 126,382,224 A171T probably damaging Het
Tlk2 T A 11: 105,247,592 I322N probably benign Het
Tubb4a A G 17: 57,086,072 V66A probably benign Het
Ubxn2a C T 12: 4,883,956 A152T probably benign Het
Ush2a A T 1: 188,753,522 D2943V probably damaging Het
Wdr62 A G 7: 30,261,339 V55A probably damaging Het
Zfp609 A G 9: 65,702,763 Y973H probably benign Het
Other mutations in Clec4b2
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL01753:Clec4b2 APN 6 123202210 missense possibly damaging 0.90
IGL02168:Clec4b2 APN 6 123204197 missense probably damaging 0.98
IGL02388:Clec4b2 APN 6 123202228 splice site probably null
IGL03194:Clec4b2 APN 6 123200987 missense probably benign 0.07
P0041:Clec4b2 UTSW 6 123181294 missense possibly damaging 0.72
R0013:Clec4b2 UTSW 6 123202149 missense probably damaging 1.00
R0121:Clec4b2 UTSW 6 123204172 missense probably benign 0.02
R0401:Clec4b2 UTSW 6 123181300 nonsense probably null
R1072:Clec4b2 UTSW 6 123204274 missense probably damaging 0.99
R2520:Clec4b2 UTSW 6 123200983 missense probably damaging 1.00
R4575:Clec4b2 UTSW 6 123173680 missense probably damaging 0.99
R4897:Clec4b2 UTSW 6 123201040 nonsense probably null
R4898:Clec4b2 UTSW 6 123204204 missense probably benign 0.36
R5022:Clec4b2 UTSW 6 123200956 missense probably null 1.00
R5023:Clec4b2 UTSW 6 123200956 missense probably null 1.00
R5057:Clec4b2 UTSW 6 123200956 missense probably null 1.00
R5404:Clec4b2 UTSW 6 123181349 missense probably benign 0.06
R5508:Clec4b2 UTSW 6 123173042 start gained probably benign
R6082:Clec4b2 UTSW 6 123204141 critical splice acceptor site probably null
R6333:Clec4b2 UTSW 6 123200678 unclassified probably null
R6902:Clec4b2 UTSW 6 123201028 nonsense probably null
R6946:Clec4b2 UTSW 6 123201028 nonsense probably null
R7144:Clec4b2 UTSW 6 123181384 missense probably benign 0.02
Posted On2013-04-17